Papers Published

1. Zawadzki, R.J. and Jones, S.M. and Olivier, S.S. and Mingtao Zhao and Bower, B.A. and Izatt, J.A., Adaptive-optics optical coherence tomography for high-resolution and high-speed 3D retinal in vivo imaging, Opt. Express (USA), vol. 13 no. 21 (2005) .
   (last updated on 2007/04/13)

   Abstract:
   We have combined Fourier-domain optical coherence tomography (FD-OCT) with a closed-loop adaptive optics (AO) system using a Hartmann-Shack wavefront sensor and a bimorph deformable mirror. The adaptive optics system measures and corrects the wavefront aberration of the human eye for improved lateral resolution (~4 μm) of retinal images, while maintaining the high axial resolution ((~6 μm) of stand alone OCT. The AO-OCT instrument enables the three-dimensional (3D) visualization of different retinal structures in vivo with high 3D resolution (4×4×6 μm). Using this system, we have demonstrated the ability to image microscopic blood vessels and the cone photoreceptor mosaic

   Keywords:
   aberrations;adaptive optics;biomedical measurement;biomedical optical imaging;blood vessels;eye;image resolution;image sensors;mirrors;optical tomography;wavefront sensors;