publications by Joseph A. Izatt.


Papers Published

  1. Kulkarni, M.D. and Izatt, J.A., Digital signal processing in optical coherence tomography, Proc. SPIE - Int. Soc. Opt. Eng. (USA), vol. 2981 (1997), pp. 2 - 6 [12.274307] .
    (last updated on 2007/04/13)

    Abstract:
    Optical Coherence Tomography (OCT) is a novel medical imaging modality which utilizes coherence ranging to perform high resolution (~10 μm) non-invasive sub-surface imaging of biostructures. The authors have developed an OCT system consisting of a low-coherence interferometer and a calibration interferometer allowing sub-micron interferogram acquisition accuracy. They propose some digital signal processing strategies for image enhancement in optical coherence tomography. A linear shift invariant system model is presented for describing coherent light-tissue interactions in optical coherence tomography. In this model, the electric field backscattered from a target specimen is treated as a convolution of the incident field and a postulated tissue impulse response which describes the profile of scattering sites within the specimen. Based on this model, a novel technique for enhancing the sharpness of optical coherence tomographic images of biological structures using digital deconvolution is demonstrated. Using this approach, resolution improvement by a factor of >2.2 is achieved in the longitudinal direction

    Keywords:
    image enhancement;laser applications in medicine;light coherence;medical image processing;optical tomography;