Papers Published

1. Yazdanfar, Siavash and Kulkarni, Manish D. and Izatt, Joseph A., High resolution imaging of in vivo cardiac dynamics using color Doppler optical coherence tomography, Optics Express, vol. 1 no. 13 (1997), pp. 424 - 431 .
   (last updated on 2007/04/13)

   Abstract:
   Color Doppler optical coherence tomography (CDOCT) is a noninvasive technique for simultaneous high spatial resolution ( [similar to] 20 μm) imaging and high velocity resolution ( [similar to] 500 μm/s) imaging flowmetry in living tissues. In this paper, we demonstrate a reconstruction method which overcomes fundamental limitations on Doppler flow mapping associated with both high- and low-speed imaging. This algorithm is successful in retaining the high velocity resolution of CDOCT while eliminating motion artifact caused by slow image acquisition in samples which exhibit repetitive motion. We demonstrate reconstruction of blood flow throughout a beating Xenopus laevis heart and surrounding vasculature using gated CDOCT reconstruction. © 1997 Optical Society of America.

   Keywords:
   Tomography;Cardiology;Biomedical engineering;Noninvasive medical procedures;Doppler effect;Optical resolving power;Medical imaging;Microcirculation;Coherent light;Microstructure;Velocity measurement;Algorithms;