Dr. Tian's research interests include synthetic systems biology, genome science, and bionanoengineering. The lab is currently focusing on developing and applying high-throughput gene and genome synthesis and optimization technologies to create novel or better synthetic biomolecules and biosystems. Ongoing research projects include:

High-throughput gene and genome synthesis platforms
High-throughput protein design, evolution, and optimization
DNA vaccine and gene therapy
Metabolic engineering
BioMEMS, instrumentation, and software development

The lab conducts highly interdisciplinary research and welcomes talents with specialized knowledge and skills from diverse backgrounds, such as biomedical-, chemical-, electrical- and mechanical-engineering, as well as experimental and computational biology.

Contact Info:

Office Location:	1383 Fciemas
Office Phone:	+1 919 684 3494
Email Address:
Web Page:

Teaching (Fall 2008):  (typical courses)

• BME 258L.01, GENOME SCIENCE TECHNOLOGY LAB

  Teer 114, TuTh 10:05 AM-11:20 AM

Education:

PhD, SUNY Stony Brook

Postdoctoral, Harvard Medical School

Awards, Honors, and Distinctions

Hartwell Individual Biomedical Research Award, 2007
Beckman Young Investigator Award, 2006
Life Sciences Research Foundation Postdoctoral Fellow, 1999
Sigma Xi Excellence in Graduate Research Award, 1997

Representative Publications

1. Saaem I and Tian J, E-beam nanopatterned photo-responsive bacteriorhodopsin-containing hydrogels, Advanced Materials, vol. 19 (November, 2007), pp. 4268-71 .
2. Reza F, Chandran K, Feltz M, Heinz A, Josephs E, O’Brien P, Dyke B, Chung H, Indurkhya S, lakhani N, Lee J, Lin S, Tang N, LaBean T, You L, Yuan F, and Tian J, Engineering novel synthetic biological systems, IET Synthetic Biology, vol. 1 (2007), pp. 48-52 .
3. Reza F, Zuo P and Tian J., Protein interfacial pocket engineering via coupled computational filtering and biological focusing criterion, Annals of Biomedical Engineering (Special Issue: Systems Biology, Bioinformatics, and Computational Biology), vol. 35 (2007), pp. 1026-1036 .
4. Tian J, Gong H, Sheng N, Zhou X, Gulari E, Gao X, and Church GM, Accurate multiplex gene synthesis from programmable DNA microchips, Nature, vol. 432 no. 7020 (2004), pp. 1050 - 1054 [nature03151] .
5. Tian J, Kim S, Heilig E, Ruderman JV, Identification of xPR-1, a progesterone receptor required for Xenopus oocyte activation, Proc Natl Acad Sci USA, vol. 97 (2001), pp. 14358-63 .