Jingdong Tian, Assistant Professor  


Jingdong Tian

Dr. Tian's research interests include synthetic biology, advanced biomolecular and biosystems engineering and genome science.

The lab currently has two focus areas:
1) Developing enabling technologies for large scale synthetic biology and functional genomics.
2) Applying high-throughput gene and genome synthesis and optimization technologies for understanding design principles of natural and synthetic biological systems.

Ongoing projects include:
Developing high-throughput, high-fidelity and low-cost gene and genome synthesis platform;
Developing efficient and reliable gene design and protein expression optimization technology;
Developing efficient protein design and directed evolution strategies;
Metabolic engineering;
BioMEMS, instrumentation, and software development.

Contact Info:
Office Location:  1383 Fciemas
Office Phone:  (919) 684-3494
Email Address:   send me a message
Web Page:

Education:

PhD, Stony Brook University
Postdoctoral, Harvard Medical School
Research Interests: Dr. Tian's research interests include synthetic biology, advanced biomolecular and biosystems engineering and genome science.

Awards, Honors, and Distinctions

Hartwell Individual Biomedical Research Award
Beckman Young Investigator Award
Life Sciences Research Foundation Postdoctoral Fellow
Sigma Xi Excellence in Graduate Research Award
Typical Courses Taught:

  • BME 258L, GENOME SCIENCE TECHNOLOGY LAB
  • BME 83L, INTRO TO BIOMATERIALS Synopsis
Representative Publications   (More Publications)

  1. Quan J, Saaem I, Tang N, Ma S, Negre N, Gong H, White KP & Tian J., Parallel on-chip gene synthesis and application to optimization of protein expression, Nature Biotechnology, vol. 29 (2011), pp. 449-452 [html] .
  2. Quan J & Tian J, Circular polymerase extension cloning for high-throughput cloning of complex and combinatorial DNA libraries, Nature Protocols, vol. 6 (2011), pp. 242-251 [html] .
  3. Ma S, Saaem I, and Tian J, Error correction in gene synthesis technology, Trends in Biotechnology (2011) (Epub ahead of Print.) [S0167-7799(11)00179-X] .
  4. Saaem I, Ma S, Quan J, and Tian J, Error correction of microchip synthesized genes using Surveyor nuclease, Nucleic Acids Research (2011) (Epub ahead of Print.) [full] .
  5. Tian J, Gong H, Sheng N, Zhou X, Gulari E, Gao X, and Church GM, Accurate multiplex gene synthesis from programmable DNA microchips, Nature, vol. 432 (2004), pp. 1050-1054 [nature03151] .