Jingdong Tian, Assistant Professor
Dr. Tian's research interests include synthetic biology, advanced biomolecular and biosystems engineering and genome science.
The lab currently has two focus areas:
1) Developing enabling technologies for large scale synthetic biology and functional genomics.
2) Applying high-throughput gene and genome synthesis and optimization technologies for understanding design principles of natural and synthetic biological systems.
Ongoing projects include:
Developing high-throughput, high-fidelity and low-cost gene and genome synthesis platform;
Developing efficient and reliable gene design and protein expression optimization technology;
Developing efficient protein design and directed evolution strategies;
BioMEMS, instrumentation, and software development.
|Office Location:||1383 Fciemas|
|Office Phone:||(919) 684-3494|
- PhD, Stony Brook University
- Postdoctoral, Harvard Medical School
- Research Interests: Dr. Tian's research interests include synthetic biology, advanced biomolecular and biosystems engineering and genome science.
- Awards, Honors, and Distinctions
Hartwell Individual Biomedical Research Award
Beckman Young Investigator Award
Life Sciences Research Foundation Postdoctoral Fellow
Sigma Xi Excellence in Graduate Research Award
- BME 258L, GENOME SCIENCE TECHNOLOGY LAB
- BME 83L, INTRO TO BIOMATERIALS
- Representative Publications
- Quan J, Saaem I, Tang N, Ma S, Negre N, Gong H, White KP & Tian J., Parallel on-chip gene synthesis and application to optimization of protein expression, Nature Biotechnology, vol. 29 (2011), pp. 449-452 [html] .
- Quan J & Tian J, Circular polymerase extension cloning for high-throughput cloning of complex and combinatorial DNA libraries, Nature Protocols, vol. 6 (2011), pp. 242-251 [html] .
- Ma S, Saaem I, and Tian J, Error correction in gene synthesis technology, Trends in Biotechnology (2011) (Epub ahead of Print.) [S0167-7799(11)00179-X] .
- Saaem I, Ma S, Quan J, and Tian J, Error correction of microchip synthesized genes using Surveyor nuclease, Nucleic Acids Research (2011) (Epub ahead of Print.) [full] .
- Tian J, Gong H, Sheng N, Zhou X, Gulari E, Gao X, and Church GM, Accurate multiplex gene synthesis from programmable DNA microchips, Nature, vol. 432 (2004), pp. 1050-1054 [nature03151] .