publications by Kam W. Leong.


Papers Published

  1. K.W. Leong, Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes (2013) [PDF].
  2. K.W. Leong, Tuning Physical Properties of Nanocomplexes through Microfluidics-Assisted Confinement (2013) [PDF].
  3. K.W. Leong, Nucleic acid scavengers inhibit thrombosis without increasing bleeding (2013) [PDF].
  4. K.W. Leong, Nanotopography as modulator of human mesenchymal stem cell function (2013) [PDF].
  5. K.W. Leong, Efficacy of engineered FVIII-producing skeletal muscle enhanced by growth factor-releasing co-axial electrospun fibers (2013) [PDF].
  6. Zhao, F. and Veldhuis, J. J. and Duan, Y. J. and Yang, Y. and Christoforou, N. and Ma, T. and Leong, K. W., Low Oxygen Tension and Synthetic Nanogratings Improve the Uniformity and Stemness of Human Mesenchymal Stem Cell Layer, Molecular Therapy, vol. 18 no. 5 (2010), pp. 1010-1018  [abs].
  7. Kadiyala, I. and Loo, Y. H. and Roy, K. and Rice, J. and Leong, K. W., Transport of chitosan-DNA nanoparticles in human intestinal M-cell model versus normal intestinal enterocytes, European Journal of Pharmaceutical Sciences, vol. 39 no. 1-3 (2010), pp. 103-109  [abs].
  8. Wang, Y. and Quek, C. H. and Leong, K.W. and Fang, J., Synthesis and Cytotoxity of Luminescent InP Quantum Dots, MRS Symposium Proceeding, vol. 1241E (2010) .
  9. Jiang, X. and Zheng, Y. and Chen, H. H. and Leong, K. W. and Wang, T. H. and Mao, H. Q., Dual-Sensitive Micellar Nanoparticles Regulate DNA Unpacking and Enhance Gene-Delivery Efficiency, Adv Mater (2010) .
  10. Ho, Y. P. and Leong, K. W., Quantum dot-based theranostics, Nanoscale, vol. 2 no. 1 (2010), pp. 60-68 [PDF[abs].
  11. Phua, K. and Leong, K. W., Microscale oral delivery devices incorporating nanoparticles, Nanomedicine, vol. 5 no. 2 (2010), pp. 161-163 .
  12. Grigsby, C. L. and Leong, K. W., Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery, Journal of the Royal Society Interface, vol. 7 (2010), pp. S67-S82  [abs].
  13. Chalut, K. J. and Kulangara, K. and Giacomelli, M. G. and Wax, A. and Leong, K. W., Deformation of stem cell nuclei by nanotopographical cues, Soft Matter, vol. 6 no. 8 (2010), pp. 1675-1681  [abs].
  14. Chen, S. and Jones, J. A. and Xu, Y. and Low, H. Y. and Anderson, J. M. and Leong, K. W., Characterization of topographical effects on macrophage behavior in a foreign body response model, Biomaterials, vol. 31 no. 13 (2010), pp. 3479-91 [PDF[abs].
  15. Yim, E. K. F. and Darling, E. M. and Kulangara, K. and Guilak, F. and Leong, K. W., Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells, Biomaterials, vol. 31 no. 6 (2010), pp. 1299-1306 [PDF[abs].
  16. Yow, S. Z. and Quek, C. H. and Yim, E. K. F. and Lim, C. T. and Leong, K. W., Collagen-based fibrous scaffold for spatial organization of encapsulated and seeded human mesenchymal stem cells, Biomaterials, vol. 30 no. 6 (2009), pp. 1133-1142  [abs].
  17. Kunder, C. A. and John, A. L. S. and Li, G. J. and Leong, K. W. and Berwin, B. and Staats, H. F. and Abraham, S. N., Mast cell-derived particles deliver peripheral signals to remote lymph nodes, Journal of Experimental Medicine, vol. 206 no. 11 (2009), pp. 2455-2467  [abs].
  18. Ho, Y.P. and Chen, H.H. and Leong, K.W. and Wang, T.H., Combining QD-FRET and microfluidics to monitor DNA nanocomplex self-assembly in real-time, J Vis Exp (2009), pp. 1432 .
  19. Kulangara, K. and Leong, K. W., Substrate topography shapes cell function, Soft Matter, vol. 5 no. 21 (2009), pp. 4072-4076  [abs].
  20. Chakraborty, S. and Liao, I. C. and Adler, A. and Leong, K. W., Electrohydrodynamics: A facile technique to fabricate drug delivery systems, Advanced Drug Delivery Reviews, vol. 61 no. 12 (2009), pp. 1043-1054  [abs].
  21. Oney, S. and Lam, R. T. S. and Bompiani, K. M. and Blake, C. M. and Quick, G. and Heidel, J. D. and Liu, J. Y. C. and Mack, B. C. and Davis, M. E. and Leong, K. W. and Sullenger, B. A., Development of universal antidotes to control aptamer activity, Nature Medicine, vol. 15 no. 10 (2009), pp. 1224-1228 [PDF[abs].
  22. Chen, H. H. and Ho, Y. P. and Jiang, X. and Mao, H. Q. and Wang, T. H. and Leong, K. W., Simultaneous non-invasive analysis of DNA condensation and stability by two-step QD-FRET, Nano Today, vol. 4 no. 2 (2009), pp. 125-134 [PDF[abs].
  23. Ho, Y. P. and Chen, H. H. and Leong, K. W. and Wang, T. H., The convergence of quantum-dot-mediated fluorescence resonance energy transfer and microfluidics for monitoring DNA polyplex self-assembly in real time, Nanotechnology, vol. 20 no. 9 (2009), pp. -  [abs].
  24. Liao, I. C. and Chen, S. L. and Liu, J. B. and Leong, K. W., Sustained viral gene delivery through core-shell fibers, Journal of Controlled Release, vol. 139 no. 1 (2009), pp. 48-55  [abs].
  25. Lou, Y. L. and Peng, Y. S. and Chen, B. H. and Wang, L. F. and Leong, K. W., Poly(ethylene imine)-g-chitosan using EX-810 as a spacer for nonviral gene delivery vectors, Journal of Biomedical Materials Research Part A, vol. 88A no. 4 (2009), pp. 1058-1068  [abs].
  26. Chew, S. Y. and Mi, R. and Hoke, A. and Leong, K. W., The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation, Biomaterials, vol. 29 no. 6 (2008), pp. 653-61  [abs].
  27. Chen, H. H. and Ho, Y. P. and Jiang, X. and Mao, H. Q. and Wang, T. H. and Leong, K. W., Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum Dot-FRET, Molecular Therapy, vol. 16 no. 2 (2008), pp. 324-332  [abs].
  28. Chan, B. P. and Leong, K. W., Scaffolding in tissue engineering: general approaches and tissue-specific considerations, European Spine Journal, vol. 17 (2008), pp. S467-S479  [abs].
  29. Tsurushima, H. and Yuan, X. and Dillehay, L. E. and Leong, K. W., Radiation-inducible caspase-8 gene therapy for malignant brain tumors, International Journal of Radiation Oncology Biology Physics, vol. 71 no. 2 (2008), pp. 517-525  [abs].
  30. Bowman, K. and Sarkar, R. and Raut, S. and Leong, K. W., Gene transfer to hemophilia A mice via oral delivery of FVIII-chitosan nanoparticles, Journal of Controlled Release, vol. 132 no. 3 (2008), pp. 252-259  [abs].
  31. Choi, J. S. and Leong, K. W. and Yoo, H. S., In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF), Biomaterials, vol. 29 no. 5 (2008), pp. 587-96  [abs].
  32. Liao, I. C. and Liu, J. B. and Bursac, N. and Leong, K. W., Effect of Electromechanical Stimulation on the Maturation of Myotubes on Aligned Electrospun Fibers, Cellular and Molecular Bioengineering, vol. 1 no. 2-3 (2008), pp. 133-145  [abs].
  33. Prow, T. W. and Bhutto, I. and Kim, S. Y. and Grebe, R. and Merges, C. and McLeod, D. S. and Uno, K. and Mennon, M. and Rodriguez, L. and Leong, K. and Lutty, G. A., Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium, Nanomedicine-Nanotechnology Biology and Medicine, vol. 4 no. 4 (2008), pp. 340-349  [abs].
  34. Tan, S. C. W. and Pan, W. X. and Ma, G. and Cai, N. and Leong, K. W. and Liao, K., Viscoelastic behaviour of human mesenchymal stem cells, Bmc Cell Biology, vol. 9 (2008), pp. -  [abs].
  35. Chalut, K. J. and Chen, S. and Finan, J. D. and Giacomelli, M. G. and Guilak, F. and Leong, K. W. and Wax, A., Label-free, high-throughput measurements of dynamic changes in cell nuclei using angle-resolved low coherence interferometry, Biophysical Journal, vol. 94 no. 12 (2008), pp. 4948-4956  [abs].
  36. Haider, M. and Cappello, J. and Ghandehari, H. and Leong, K. W., In vitro chondrogenesis of mesenchymal stem cells in recombinant silk-elastinlike hydrogels, Pharmaceutical Research, vol. 25 no. 3 (2008), pp. 692-699  [abs].
  37. N. Bursac and Y. H. Loo and K. Leong and L. Tung, Novel anisotropic engineered cardiac tissues: Studies of electrical propagation, Biochemical And Biophysical Research Communications, vol. 361 no. 4 (October, 2007), pp. 847 -- 853  [abs].
  38. Chen, Beiyi and Dang, Jiyoung and Tan, Tuan Lin and Fang, Ning and Chen, Wei Ning and Leong, Kam W. and Chan, Vincent, Dynamics of smooth muscle cell deadhesion from thermosensitive hydroxybutyl chitosan, Biomaterials, vol. 28 no. 8 (2007), pp. 1503 - 1514 [027]  [abs].
  39. Chen, B. and Dang, J. and Tan, T. L. and Fang, N. and Chen, W. N. and Leong, K. W. and Chan, V., Dynamics of smooth muscle cell deadhesion from thermosensitive hydroxybutyl chitosan, Biomaterials, vol. 28 no. 8 (2007), pp. 1503-14  [abs].
  40. Park, D. J. and Choi, J. H. and Leong, K. W. and Kwon, J. W. and Eun, H. S., Tissue-engineered bone formation with gene transfer and mesenchymal stem cells in a minimally invasive technique, Laryngoscope, vol. 117 no. 7 (2007), pp. 1267-71  [abs].
  41. Tsurushima, H. and Yuan, X. and Dillehay, L. E. and Leong, K. W., Radioresponsive tumor necrosis factor-related apoptosisinducing ligand (TRAIL) gene therapy for malignant brain tumors, Cancer Gene Therapy, vol. 14 no. 8 (2007), pp. 706-716  [abs].
  42. Chai, C. and Leong, K. W., Biomaterials approach to expand and direct differentiation of stem cells, Molecular Therapy, vol. 15 no. 3 (2007), pp. 467-480  [abs].
  43. Zhang, Y. and Chai, C. and Jiang, X. S. and Teoh, S. H. and Leong, K. W., Fibronectin immobilized by covalent conjugation or physical adsorption shows different bioactivity on aminated-PET, Materials Science & Engineering C-Biomimetic and Supramolecular Systems, vol. 27 no. 2 (2007), pp. 213-219  [abs].
  44. Song, R. J. and Liu, S. Q. and Leong, K. W., Effects of MIP-1 alpha, MIP-3 alpha, and MIP-3 beta on the induction of HIV Gag-specific immune response with DNA vaccines, Molecular Therapy, vol. 15 no. 5 (2007), pp. 1007-1015  [abs].
  45. Yim, E. K. F. and Liao, I. C. and Leong, K. W., Tissue compatibility of interfacial polyelectrolyte complexation fibrous scaffold: Evaluation of blood compatibility and biocompatibility, Tissue Engineering, vol. 13 no. 2 (2007), pp. 423-433  [abs].
  46. Sharma, B. and Williams, C. G. and Kim, T. K. and Sun, D. N. and Malik, A. and Khan, M. and Leong, K. and Elisseeff, J. H., Designing zonal organization into tissue-engineered cartilage, Tissue Engineering, vol. 13 no. 2 (2007), pp. 405-414  [abs].
  47. Chua, K. N. and Tang, Y. N. and Quek, C. H. and Ramakrishna, S. and Leong, K. W. and Mao, H. Q., A dual-functional fibrous scaffold enhances P450 activity of cultured primary rat hepatocytes, Acta Biomaterialia, vol. 3 no. 5 (2007), pp. 643-650  [abs].
  48. Chua, K. N. and Chai, C. and Lee, P. C. and Ramakrishna, S. and Leong, K. W. and Mao, H. Q., Functional nanofiber scaffolds with different spacers modulate adhesion and expansion of cryopreserved umbilical cord blood hematopoietic stem/progenitor cells, Experimental Hematology, vol. 35 no. 5 (2007), pp. 771-781  [abs].
  49. Yim, E. K. F. and Pang, S. W. and Leong, K. W., Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage, Experimental Cell Research, vol. 313 no. 9 (2007), pp. 1820-1829  [abs].
  50. Chew, S. Y. and Mi, R. F. and Hoke, A. and Leong, K. W., Aligned protein-polymer composite fibers enhance nerve regeneration: A potential tissue-engineering platform, Advanced Functional Materials, vol. 17 no. 8 (2007), pp. 1288-1296  [abs].
  51. Tsurushima, H. and Yuan, X. and Dillehay, L. E. and Leong, K. W., Radio-responsive gene therapy for malignant glioma cells without the radiosensitive promoter: Caspase-3 gene therapy combined with radiation, Cancer Letters, vol. 246 no. 1-2 (2007), pp. 318-323  [abs].
  52. Dang, J.M. and Leong, K. W., Myogenic induction of aligned mesenchymal stem cell sheets by culture on thermally responsive electrospun nanofibers, Advanced Materials, vol. 19 no. 19 (2007), pp. 2775-2779 .
  53. Dai, H. and Jiang, X. and Tan, G. C. and Chen, Y. and Torbenson, M. and Leong, K. W. and Mao, H. Q., Chitosan-DNA nanoparticles delivered by intrabiliary infusion enhance liver-targeted gene delivery, International Journal of Nanomedicine, vol. 1 no. 4 (2006), pp. 507-522  [abs].
  54. Le Visage, C. and Kim, S. W. and Tateno, K. and Sieber, A. N. and Kostuik, J. P. and Leong, K. W., Interaction of human mesenchymal stem cells with disc cells - Changes in extracellular matrix biosynthesis, Spine, vol. 31 no. 18 (2006), pp. 2036-2042 .
  55. Ong, S. Y. and Dai, H. and Leong, K. W., Inducing hepatic differentiation of human mesenchymal stem cells in pellet culture, Biomaterials, vol. 27 no. 22 (2006), pp. 4087-4097 .
  56. Bright, C. and Park, Y. S. and Sieber, A. N. and Kostuik, J. P. and Leong, K. W., In vivo evaluation of plasmid DNA encoding OP-1 protein for spine fusion, Spine, vol. 31 no. 19 (2006), pp. 2163-2172 .
  57. Yim, E. K. and Wan, A. C. and Le Visage, C. and Liao, I. C. and Leong, K. W., Proliferation and differentiation of human mesenchymal stem cell encapsulated in polyelectrolyte complexation fibrous scaffold, Biomaterials, vol. 27 no. 36 (2006), pp. 6111-22  [abs].
  58. Luong-Van, E. and Grondahl, L. and Chua, K. N. and Leong, K. W. and Nurcombe, V. and Cool, S. M., Controlled release of heparin from poly(epsilon-caprolactone) electrospun fibers, Biomaterials, vol. 27 no. 9 (2006), pp. 2042-2050 .
  59. Dang, J. M. and Leong, K. W., Natural polymers for gene delivery and tissue engineering, Advanced Drug Delivery Reviews, vol. 58 no. 4 (2006), pp. 487-499 .
  60. Li, J. and Li, X. and Ni, X. P. and Wang, X. and Li, H. Z. and Leong, K. W., Self-assembled supramolecular hydrogels formed by biodegradable PEO-PHB-PEO triblock copolymers and alpha-cyclodextrin for controlled drug delivery, Biomaterials, vol. 27 no. 22 (2006), pp. 4132-4140 .
  61. Yim, E. K. F. and Wen, J. and Leong, K. W., Enhanced extracellular matrix production and differentiation of human embryonic germ cell derivatives in biodegradable poly(epsilon-caprolactone-co-ethyl ethylene phosphate) scaffold, Acta Biomaterialia, vol. 2 no. 4 (2006), pp. 365-376 .
  62. Chew, S. Y. and Hufnagel, T. C. and Lim, C. T. and Leong, K. W., Mechanical properties of single electrospun drug-encapsulated nanofibres, Nanotechnology, vol. 17 no. 15 (2006), pp. 3880-3891 .
  63. Zhang, Y. and Chai, C. and Jiang, X. S. and Teoh, S. H. and Leong, K. W., Co-culture of umbilical cord blood CD34(+) cells with human mesenchymal stem cells, Tissue Engineering, vol. 12 no. 8 (2006), pp. 2161-2170 .
  64. Chen, H. H. and Leong, K. W., Quantum-dots-FRET nanosensors for detecting unamplified nucleic acids by single molecule detection, Nanomedicine, vol. 1 no. 1 (2006), pp. 119-122  [abs].
  65. Wu, D. C. and Liu, Y. and Jiang, X. and He, C. B. and Goh, S. H. and Leong, K. W., Hyperbranched poly(amino ester)s with different terminal amine groups for DNA delivery, Biomacromolecules, vol. 7 no. 6 (2006), pp. 1879-1883 .
  66. Li, Q. and Wang, J. and Shahani, S. and Sun, D. D. N. and Sharma, B. and Elisseeff, J. H. and Leong, K. W., Biodegradable and photocrosslinkable polyphosphoester hydrogel, Biomaterials, vol. 27 no. 7 (2006), pp. 1027-1034 .
  67. Bowman, K. and Leong, K. W., Chitosan nanoparticles for oral drug and gene delivery, International Journal of Nanomedicine, vol. 1 no. 2 (2006), pp. 117-128  [abs].
  68. Jiang, X. S. and Chai, C. and Zhang, Y. and Zhuo, R. X. and Mao, H. Q. and Leong, K. W., Surface-immobilization of adhesion peptides on substrate for ex vivo expansion of cryopreserved umbilical cord blood CD34(+) cells, Biomaterials, vol. 27 no. 13 (2006), pp. 2723-2732 .
  69. Tsurushima, H. and Yoshii, Y. and Leong, K. and Ohno, T., Targeted tumor cell death induced by autologous tumor-specific T lymphocyte recognition of wild-type p53-derived peptides, Journal of Neuro-Oncology, vol. 76 no. 2 (2006), pp. 99-104 .
  70. Lim, S. H. and Liao, I. C. and Leong, K. W., Nonviral gene delivery from nonwoven fibrous scaffolds fabricated by interfacial complexation of polyelectrolytes, Molecular Therapy, vol. 13 no. 6 (2006), pp. 1163-1172 .
  71. Song, R. J. and Liu, S. Q. and Adams, R. J. and Leong, K. W., Enhancing efficacy of HIV Gag DNA vaccine by local delivery of GM-CSF in murine and macaque models, Journal of Interferon and Cytokine Research, vol. 26 no. 6 (2006), pp. 380-389 .
  72. Dang, J. M. and Sun, D. D. N. and Shin-Ya, Y. and Sieber, A. N. and Kostuik, J. P. and Leong, K. W., Temperature-responsive hydroxybutyl chitosan for the culture of mesenchymal stem cells and intervertebral disk cells, Biomaterials, vol. 27 no. 3 (2006), pp. 406-418 .
  73. Jiang, X. and Dai, H. and Leong, K. W. and Goh, S. H. and Mao, H. Q. and Yang, Y. Y., Chitosan-g-PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions, Journal of Gene Medicine, vol. 8 no. 4 (2006), pp. 477-487 .
  74. Li, J. and Yang, C. and Li, H. Z. and Wang, X. and Goh, S. H. and Ding, J. L. and Wang, D. Y. and Leong, K. W., Cationic supramolecules composed of multiple oligoethylenimine-grafted beta-cyclodextrins threaded on a polymer chain for efficient gene delivery, Advanced Materials, vol. 18 no. 22 (2006), pp. 2969-2974  [abs].
  75. Le Visage, C. and Yang, S. H. and Kadakia, L. and Sieber, A. N. and Kostuik, J. P. and Leong, K. W., Small intestinal submucosa as a potential bioscaffold for intervertebral disc regeneration, Spine, vol. 31 no. 21 (2006), pp. 2423-2430 .
  76. Chew, S. Y. and Wen, Y. and Dzenis, Y. and Leong, K. W., The role of electrospinning in the emerging field of nanomedicine, Current Pharmaceutical Design, vol. 12 no. 36 (2006), pp. 4751-4770  [abs].
  77. Chua, K. N. and Chai, C. and Lee, P. C. and Tang, Y. N. and Ramakrishna, S. and Leong, K. W. and Mao, H. Q., Surface-aminated electrospun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cells, Biomaterials, vol. 27 no. 36 (2006), pp. 6043-51  [abs].
  78. Feng, Q. and Chai, C. and Jiang, X. S. and Leong, K. W. and Mao, H. Q., Expansion of engrafting human hematopoietic stem/progenitor cells in three-dimensional scaffolds with surface-immobilized fibronectin, Journal of Biomedical Materials Research Part A, vol. 78A no. 4 (2006), pp. 781-791 .
  79. Wong, K. and Sun, G. B. and Zhang, X. Q. and Dai, H. and Liu, Y. and He, C. B. and Leong, K. W., PEI-g-chitosan, a novel gene delivery system with transfection efficiency comparable to polyethylenimine in vitro and after liver administration in vivo, Bioconjugate Chemistry, vol. 17 no. 1 (2006), pp. 152-158 .
  80. Ho, Y. P. and Chen, H. H. and Leong, K. W. and Wang, T. H., Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET, J Control Release, vol. 116 no. 1 (2006), pp. 83-9  [abs].
  81. Li, X. and Mya, K. Y. and Ni, X. P. and He, C. B. and Leong, K. W. and Li, J., Dynamic and static light scattering studies on self-aggregation behavior of biodegradable amphiphilic poly(ethylene oxide)-poly [(R)-3-hydroxybutyrate]-poly(ethylene oxide) triblock copolymers in aqueous solution, Journal of Physical Chemistry B, vol. 110 no. 12 (2006), pp. 5920-5926 .
  82. Liu, Ye and Wu, De-Cheng and Zhang, Wei-De and Jiang, Xuan and He, Chao-Bin and Chung, Tai Shung and Goh, Suat Hong and Leong, Kam W., Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA, Angewandte Chemie - International Edition, vol. 44 no. 30 (2005), pp. 4782 - 4785 [anie.200500042]  [abs].
  83. Lu, H. F. and Lim, W. S. and Zhang, P. C. and Chia, S. M. and Yu, H. and Mao, H. Q. and Leong, K. W., Galactosylated poly(vinylidene difluoride) hollow fiber bioreactor for hepatocyte culture, Tissue Engineering, vol. 11 no. 11-12 (2005), pp. 1667-1677 .
  84. Zhang, Xue-Qing and Wang, Xu-Li and Zhang, Peng-Chi and Liu, Zhi-Lan and Zhuo, Ren-Xi and Mao, Hai-Quan and Leong, Kam W., Galactosylated ternary DNA/polyphosphoramidate nanoparticles mediate high gene transfection efficiency in hepatocytes, Journal of Controlled Release, vol. 102 no. 3 (2005), pp. 749 - 763 [024]  [abs].
  85. Leong, Kam W., Polymeric controlled nucleic acid delivery, MRS Bulletin, vol. 30 no. 9 (2005), pp. 640 - 646  [abs].
  86. Zhang, Xue-Qing and Wang, Xu-Li and Huang, Shi-Wen and Zhuo, Ren-Xi and Liu, Zhi-Lan and Mao, Hai-Quan and Leong, Kam W., In vitro gene delivery using polyamidoamine dendrimers with a trimesyl core, Biomacromolecules, vol. 6 no. 1 (2005), pp. 341 - 350 [bm040060n]  [abs].
  87. Chia, Ser-Mien and Lin, Pao-Chun and Quek, Chai-Hoon and Yin, Chao and Mao, Hai-Quan and Leong, Kam W. and Xu, Xi and Goh, Cho-Hong and Ng, Mah-Lee and Yu, Hanry, Engineering microenvironment for expansion of sensitive anchorage-dependent mammalian cells, Journal of Biotechnology, vol. 118 no. 4 (2005), pp. 434 - 447 [012]  [abs].
  88. Zhang, X. Q. and Wang, X. L. and Huang, S. W. and Zhuo, R. X. and Liu, Z. L. and Mao, H. Q. and Leong, K. W., In vitro gene delivery using polyamidoamine dendrimers with a trimesyl core, Biomacromolecules, vol. 6 no. 1 (2005), pp. 341-350 .
  89. Chua, Kian-Ngiap and Lim, Wei-Seng and Zhang, Pengchi and Lu, Hongfang and Wen, Jie and Ramakrishna, Seeram and Leong, Kam W. and Mao, Hai-Quan, Stable immobilization of rat hepatocyte spheroids on galactosylated nanofiber scaffold, Biomaterials, vol. 26 no. 15 (2005), pp. 2537 - 2547 [040]  [abs].
  90. Pan, Wenxiao and Petersen, Erik and Cai, Ning and Ma, Gang and Lee, Jian Run and Feng, Zhiqin and Liao, Kin and Leong, Kam W., Viscoelastic properties of human mesenchymal stem cells, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, vol. 7 S (2005), pp. 4854 - 4857  [abs].
  91. Yim, Evelyn K.F. and Leong, Kam W., Significance of synthetic nanostructures in dictating cellular response, Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 1 no. 1 (2005), pp. 10 - 21 [008]  [abs].
  92. Chua, K. N. and Lim, W. S. and Zhang, P. C. and Lu, H. F. and Wen, J. and Ramakrishna, S. and Leong, K. W. and Mao, H. Q., Stable immobilization of rat hepatocyte spheroids on galactosylated nanofiber scaffold, Biomaterials, vol. 26 no. 15 (2005), pp. 2537-2547 .
  93. Lu, Hong-Fang and Lim, Wei Seng and Zhang, Peng-Chi and Chia, Ser Mien and Yu, Hanry and Mao, Hai-Quan and Leong, Kam W., Galactosylated poly(vinylidene difluoride) hollow fiber bioreactor for hepatocyte culture, Tissue Engineering, vol. 11 no. 11-12 (2005), pp. 1667 - 1677 [1667]  [abs].
  94. Fang, Ning and Wee, Jin Tan and Leong, Kam W. and Mao, Hai-Quan and Chan, Vincent, pH responsive adhesion of phospholipid vesicle on poly(acrylic acid) cushion grafted to poly(ethylene terephthalate) surface, Colloids and Surfaces B: Biointerfaces, vol. 42 no. 3-4 (2005), pp. 245 - 252 [002]  [abs].
  95. Liao, I-Chien and Wan, Andrew C.A. and Yim, Evelyn K.F. and Leong, Kam W., Controlled release from fibers of polyelectrolyte complexes, Journal of Controlled Release, vol. 104 no. 2 (2005), pp. 347 - 358 [013]  [abs].
  96. Li, Jun and Ni, Xiping and Li, Xu and Tan, Ngee Koon and Lim, Chwee Teck and Ramakrishna, Seeram and Leong, Kam W., Micellization phenomena of biodegradable amphiphilic triblock copolymers consisting of poly(β-hydroxyalkanoic acid) and poly(ethylene oxide), Langmuir, vol. 21 no. 19 (2005), pp. 8681 - 8685 [la0515266]  [abs].
  97. Zhang, Peng-Chi and Wang, Jun and Leong, Kam W. and Mao, Hai-Quan, Ternary complexes comprising polyphosphoramidate gene carriers with different types of charge groups improve transfection efficiency, Biomacromolecules, vol. 6 no. 1 (2005), pp. 54 - 60 [bm040010i]  [abs].
  98. Chia, S. M. and Lin, P. C. and Quek, C. H. and Yin, C. and Mao, H. Q. and Leong, K. W. and Xu, X. and Goh, C. H. and Ng, M. L. and Yu, H., Engineering microenvironment for expansion of sensitive anchorage-dependent mammalian cells, Journal of Biotechnology, vol. 118 no. 4 (2005), pp. 434-447 .
  99. Li, J. and Ni, X. P. and Li, X. and Tan, N. K. and Lim, C. T. and Ramakrishna, S. and Leong, K. W., Micellization phenomena of biodegradable amphiphilic triblock copolymers consisting of poly(beta-hydroxyalkanoic acid) and poly(ethylene oxide), Langmuir, vol. 21 no. 19 (2005), pp. 8681-8685 .
  100. Tan, W. J. and Teo, G. P. and Liao, K. and Leong, K. W. and Mao, H. Q. and Chan, V., Adhesion contact dynamics of primary hepatocytes on poly(ethylene terephthalate) surface, Biomaterials, vol. 26 no. 8 (2005), pp. 891-898 .
  101. Kim, M. S. and Hwang, N. S. and Lee, J. and Kim, T. K. and Leong, K. and Shamblott, M. J. and Gearhart, J. and Elisseeff, J., Musculoskeletal differentiation of cells derived from human embryonic germ cells, Stem Cells, vol. 23 no. 1 (2005), pp. 113-123 .
  102. Liu, Y. and Wu, D. C. and Zhang, W. D. and Jiang, X. and He, C. B. and Chung, T. S. and Goh, S. H. and Leong, K. W., Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA, Angewandte Chemie-International Edition, vol. 44 no. 30 (2005), pp. 4782-4785 .
  103. Zhang, P. C. and Wang, J. and Leong, K. W. and Mao, H. Q., Ternary complexes comprising polyphosphoramidate gene carriers with different types of charge groups improve transfection efficiency, Biomacromolecules, vol. 6 no. 1 (2005), pp. 54-60 .
  104. Mao, H. Q. and Shipanova-Kadiyala, I. and Zhao, Z. and Dang, W. B. and Brown, A. and Leong, K. W., Biodegradable poly(terephthalate-co-phosphate)s: synthesis, characterization and drug-release properties, Journal of Biomaterials Science-Polymer Edition, vol. 16 no. 2 (2005), pp. 135-161 .
  105. Chen, H. H. and Le Visage, C. and Qiu, B. S. and Du, X. Y. and Ouwerkerk, R. and Leong, K. W. and Yang, X. M., MR imaging of biodegradable polymeric microparticles: A potential method of monitoring local drug delivery, Magnetic Resonance in Medicine, vol. 53 no. 3 (2005), pp. 614-620 .
  106. Wu, D. C. and Liu, Y. and Jiang, X. and Chen, L. and He, C. B. and Goh, S. H. and Leong, K. W., Evaluation of hyperbranched poly(amino ester)s of amine constitutions similar to polyethylenimine for DNA delivery, Biomacromolecules, vol. 6 no. 6 (2005), pp. 3166-3173 .
  107. Salem, A. K. and Hung, C. F. and Kim, T. W. and Wu, T. C. and Searson, P. C. and Leong, K. W., Multi-component nanorods for vaccination applications, Nanotechnology, vol. 16 no. 4 (2005), pp. 484-487 .
  108. Yim, E. K. F. and Reano, R. M. and Pang, S. W. and Yee, A. F. and Chen, C. S. and Leong, K. W., Nanopattern-induced changes in morphology and motility of smooth muscle cells, Biomaterials, vol. 26 no. 26 (2005), pp. 5405-5413 .
  109. Lu, H. F. and Chua, K. N. and Zhang, P. C. and Lim, W. S. and Ramakrishna, S. and Leong, K. W. and Mao, H. Q., Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance, Acta Biomaterialia, vol. 1 no. 4 (2005), pp. 399-410 .
  110. Chew, S. Y. and Wen, J. and Yim, E. K. F. and Leong, K. W., Sustained release of proteins from electrospun biodegradable fibers, Biomacromolecules, vol. 6 no. 4 (2005), pp. 2017-2024 .
  111. Fang, N. and Tan, W. J. and Leong, K. W. and Mao, H. Q. and Chan, V., pH responsive adhesion of phospholipid vesicle on poly(acrylic acid) cushion grafted to poly(ethylene terephthalate) surface, Colloids and Surfaces B-Biointerfaces, vol. 42 no. 3-4 (2005), pp. 245-252 .
  112. Yim, E. K. F. and Leong, K. W., Proliferation and differentiation of human embryonic germ cell derivatives in bioactive polymeric fibrous scaffold, Journal of Biomaterials Science-Polymer Edition, vol. 16 no. 10 (2005), pp. 1193-1217 .
  113. Kuang, M. and Liu, S. Q. and Saijo, K. and Uchimura, E. and Huang, L. and Leong, K. W. and Lu, M. D. and Huang, J. F. and Ohno, T., Microwave tumour coagulation plus in situ treatment with cytokine-microparticles: Induction of potent anti-residual tumour immunity, International Journal of Hyperthermia, vol. 21 no. 3 (2005), pp. 247-257 .
  114. Zhang, X. Q. and Wang, X. L. and Zhang, P. C. and Liu, Z. L. and Zhuo, R. X. and Mao, H. Q. and Leong, K. W., Galactosylated ternary DNA/polyphosphoramidate nanoparticles mediate high gene transfection efficiency in hepatocytes, Journal of Controlled Release, vol. 102 no. 3 (2005), pp. 749-763 .
  115. Mao, H. Q. and Leong, K. W., Design of polyphosphoester-DNA nanoparticles for non-viral gene delivery, Adv Genet, vol. 53 (2005), pp. 275-306  [abs].
  116. Liao, I. C. and Wan, A. C. A. and Yim, E. K. F. and Leong, K. W., Controlled release from fibers of polyelectrolyte complexes, Journal of Controlled Release, vol. 104 no. 2 (2005), pp. 347-358 .
  117. Hu, W. and Yim, E. K. F. and Reano, R. M. and Leong, K. W. and Pang, S. W., Effects of nanoimprinted patterns in tissue-culture polystyrene on cell behavior, Journal of Vacuum Science & Technology B, vol. 23 no. 6 (2005), pp. 2984-2989 .
  118. Chen, H.H. and Le Visage, C. and Bensheng Qiu and Xiangying Du and Ouwerkerk, R. and Leong, K.W. and Xiaoming Yang, MR imaging of biodegradable polymeric microparticles: a potential method of monitoring local drug delivery, Magn. Reson. Med. (USA), vol. 53 no. 3 (2005), pp. 614 - 20 [mrm.20395]  [abs].
  119. Li, Y. and Wang, J. and Lee, C. G. L. and Wang, C. Y. and Gao, S. J. and Tang, G. P. and Ma, Y. X. and Yu, H. and Mao, H. Q. and Leong, K. W. and Wang, S., CNS gene transfer mediated by a novel controlled release system based on DNA complexes of degradable polycation PPE-EA: a comparison with polyethylenimine/DNA complexes, Gene Therapy, vol. 11 no. 1 (2004), pp. 109-114 .
  120. Shin-Ya, Yoshitsune and Tsurushima, Hideo and Tsurumi, Taro and Kajiuchi, Toshio and Leong, Kam W., Polyelectrolyte complex films derived from polyethyleneoxide-maleic acid copolymer and chitosan: Preparation and characterization, Macromolecular Bioscience, vol. 4 no. 5 (2004), pp. 526 - 531 [mabi.200300110]  [abs].
  121. Kiang, T. and Bright, C. and Cheung, C.Y. and Stayton, P.S. and Hoffman, A.S. and Leong, K.W., Formulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expression, J. Biomater. Sci., Polym. Ed. (Netherlands), vol. 15 no. 11 (2004), pp. 1405 - 21 [1568562042368112]  [abs].
  122. Le Visage, Catherine and Dunham, Brian and Flint, Paul and Leong, Kam W., Coculture of mesenchymal stem cells and respiratory epithelial cells to engineer a human composite respiratory mucosa, Tissue Engineering, vol. 10 no. 9-10 (2004), pp. 1426 - 1435 [1076327042500247]  [abs].
  123. Kuang, M. and Peng, B. G. and Lu, M. D. and Liang, L. J. and Huang, J. F. and He, Q. and Hua, Y. P. and Totsuka, S. and Liu, S. Q. and Leong, K. W. and Ohno, T., Phase II randomized trial of autologous formalin-fixed tumor vaccine for postsurgical recurrence of hepatocellular carcinoma, Clinical Cancer Research, vol. 10 no. 5 (2004), pp. 1574-1579 .
  124. Wan, A.C.A. and Yim, E.K.F. and Liao, I.-C. and Chai, C. and Leong, K.W., The assembly of "biostructural units" as a new strategy for tissue engineering, Transactions - 7th World Biomaterials Congress (2004), pp. 1543 -  [abs].
  125. Chai, C. and Feng, Q. and Jiang, X.S. and Leong, K.W. and Mao, H.Q., Expansion of CD34+ cells on polymeric scaffolds surface-immobilized with hematopoietic growth factors, Transactions - 7th World Biomaterials Congress (2004), pp. 897 -  [abs].
  126. Wan, Andrew C.A. and Liao, I.-Chien and Yim, Evelyn K.F. and Leong, Kam W., Mechanism of fiber formation by interfacial polyelectrolyte complexation, Macromolecules, vol. 37 no. 18 (2004), pp. 7019 - 7025 [ma0498868]  [abs].
  127. Li, X. and Li, J. and Leong, K. W., Role of intermolecular interaction between hydrophobic blocks in block-selected inclusion complexation of amphiphilic poly(ethylene oxide)-poly[(R)-3-hydroxybutyrate]-poly(ethylene oxide) triblock copolymers with cyclodextrins, Polymer, vol. 45 no. 20 (2004), pp. 6845-6851 .
  128. Faranesh, A. Z. and Nastley, M. T. and de la Cruz, C. P. and Haller, M. F. and Laquerriere, P. and Leong, K. W. and McVeigh, E. R., In vitro release of vascular endothelial growth factor from gadolinium-doped biodegradable microspheres, Magnetic Resonance in Medicine, vol. 51 no. 6 (2004), pp. 1265-1271 .
  129. Chua, K.N. and Lim, W.S. and Lu, H.F. and Chai, C. and Zhang, P.C. and Wen, J. and Ramakrishna, S. and Leong, K.W. and Mao, H.Q., Immobilized hepatocyte spheroids on galactose ligand-conjugated nanofiber scaffold, Transactions - 7th World Biomaterials Congress (2004), pp. 1753 -  [abs].
  130. Lim, W.S. and Chua, K.N. and Wang, X.L. and Zhang, P.C. and Lu, H.F. and Leong, K.W. and Mao, H.Q., Transfection of rat primary hepatocytes using a novel polyphosphoramidate gene carrier, Transactions - 7th World Biomaterials Congress (2004), pp. 1813 -  [abs].
  131. Bini, T.B. and Gao, Shujun and Xu, Xiaoyun and Wang, Shu and Ramakrishna, S. and Leong, Kam W., Peripheral nerve regeneration by microbraided poly(L-lactide-co-glycolide) biodegradable polymer fibers, Journal of Biomedical Materials Research - Part A, vol. 68 no. 2 (2004), pp. 286 - 295 [jbm.a.20050]  [abs].
  132. Chan, Vincent and Liu, Kuo-Kang and Le Visage, Catherine and Ju, Bin-Feng and Leong, Kam W., Bioadhesive characterization of poly(methylidene malonate 2.12) microparticle on model extracellular matrix, Biomaterials, vol. 25 no. 18 (2004), pp. 4327 - 4332 [021]  [abs].
  133. Yim, E.K.F. and Wan, A. and Liao, I. and Le Visage, C. and Leong, K.W., Osteogenic and chondrogenic differentiation of human mesenchymal stem cells incorporated into polyelectrolyte fibrous scaffold, Transactions - 7th World Biomaterials Congress (2004), pp. 165 -  [abs].
  134. Sun, Daniel D.N. and Leong, Kam W., A nonlinear hyperelastic mixture theory model for anisotropy, transport, and swelling of annulus fibrosus, Annals of Biomedical Engineering, vol. 32 no. 1 (2004), pp. 92 - 102 [1e]  [abs].
  135. Li, X. and Ni, X.P. and Zhou, Z.H. and Leong, K.W. and Li, J., Injectable supramolecular hydrogels based on poly(ethylene oxide)-b-poly[(R)-3-hydroxybutyrate]-b-poly(ethylene oxide) triblock copolymers and α-cyclodextrin, Transactions - 7th World Biomaterials Congress (2004), pp. 670 -  [abs].
  136. Huang, Shi-Wen and Wang, Jun and Zhang, Peng-Chi and Mao, Hai-Quan and Zhuo, Ren-Xi and Leong, Kam W., Water-soluble and nonionic polyphosphoester: Synthesis, degradation, biocompatibility and enhancement of gene expression in mouse muscle, Biomacromolecules, vol. 5 no. 2 (2004), pp. 306 - 311 [bm034241l]  [abs].
  137. Li, J. and Ni, X. and Li, X. and Wang, X. and Zhou, Z. and Leong, K.W., A novel biodegradable amphiphilic triblock copolymer consisting of poly[(R)-β-hydroxybutyrate] and poly(ethylene oxide) and Its self-association property, Transactions - 7th World Biomaterials Congress (2004), pp. 1178 -  [abs].
  138. Sun, D. D. N. and Leong, K. W., A Nonlinear hyperelastic mixture theory model for anisotropy, transport, and swelling of annulus fibrosus, Annals of Biomedical Engineering, vol. 32 no. 1 (2004), pp. 92-102 .
  139. Leong, K.W. and Liao, I.C. and Yim, E. and Lim, S. and Wan, A. and Wen, J. and Chew, S.Y. and Chua, K.N. and Ramakrishna, S. and Mao, H.Q., Controlled release systems designed for regenerative medicine, Transactions - 7th World Biomaterials Congress (2004), pp. 189 -  [abs].
  140. Kiang, Tina and Wen, Jie and Lim, Huay Wen and Leong, Kam W., The effect of the degree of chitosan deacetylation on the efficiency of gene transfection, Biomaterials, vol. 25 no. 22 (2004), pp. 5293 - 5301 [036]  [abs].
  141. Wan, A. C. A. and Mao, H. Q. and Wang, S. and Phua, S. H. and Lee, G. P. and Pan, J. S. and Lu, S. and Wang, J. and Leong, K. W., Poly(phosphoester) ionomers as tissue-engineering scaffolds, Journal of Biomedical Materials Research Part B-Applied Biomaterials, vol. 70B no. 1 (2004), pp. 91-102 .
  142. Wan, Andrew C. A. and Yim, Evelyn K. F. and Liao, I-Chien and Le Visage, Catherine and Leong, Kam W., Encapsulation of biologics in self-assembled fibers as biostructural units for tissue engineering, Journal of Biomedical Materials Research - Part A, vol. 71 no. 4 (2004), pp. 586 - 595 [jbm.a.30158]  [abs].
  143. Salem, Aliasger K. and Chao, Johnny and Leong, Kam W. and Searson, Peter C., Receptor-mediated self-assembly of multi-component magnetic nanowires, Advanced Materials, vol. 16 no. 3 (2004), pp. 268 - 271 [adma.200305700]  [abs].
  144. Salem, Aliasger K. and Searson, Peter C. and Leong, Kam W., Multifunctional nanorods for gene delivery, Materials Research Society Symposium Proceedings, vol. EXS no. 1 (2004), pp. 455 - 457  [abs].
  145. Wang, Jun and Sun, Daniel N. and Shin-ya, Yoshitsune and Leong, Kam W., Stimuli-responsive hydrogel based on poly(propylene phosphate), Macromolecules, vol. 37 no. 2 (2004), pp. 670 - 672 [ma035453d]  [abs].
  146. Wan, Andrew C. A. and Mao, Hai-Quan and Wang, Shu and Phua, Su Hui and Lee, Gin Ping and Pan, Jisheng and Lu, Shen and Wang, Jun and Leong, Kam W., Poly(phosphoester) ionomers as tissue-engineering scaffolds, Journal of Biomedical Materials Research - Part B Applied Biomaterials, vol. 70 no. 1 (2004), pp. 91 - 102  [abs].
  147. Feng, Q. and Jiang, X.S. and Chai, C. and Lim, W.S. and Leong, K.W. and Mao, H.Q., Ex vivo expansion of hematopoietic primitive cells on ECM molecule-immobilized scaffold, Transactions - 7th World Biomaterials Congress (2004), pp. 898 -  [abs].
  148. Quek, C.H. and Li, J. and Sun, T. and Chan, M.L.H. and Mao, H.Q. and Gan, L.M. and Leong, K.W. and Yu, H., Photo-crosslinkable microcapsules formed by polyelectrolyte copolymer and modified collagen for rat hepatocyte encapsulation, Transactions - 7th World Biomaterials Congress (2004), pp. 330 -  [abs].
  149. Quek, Chai-Hoon and Li, Jun and Sun, Tao and Chan, Melinda Ling Hou and Mao, Hai-Quan and Gan, Leong Ming and Leong, Kam W. and Yu, Hanry, Photo-crosslinkable microcapsules formed by polyelectrolyte copolymer and modified collagen for rat hepatocyte encapsulation, Biomaterials, vol. 25 no. 17 (2004), pp. 3531 - 3540 [112]  [abs].
  150. Li, Xu and Li, Jun and Leong, Kam W., Role of intermolecular interaction between hydrophobic blocks in block-selected inclusion complexation of amphiphilic poly(ethylene oxide)-poly[(R)-3-hydroxybutyrate]-poly(ethylene oxide) triblock copolymers with cyclodextrins, Polymer, vol. 45 no. 20 (2004), pp. 6845 - 6851 [038]  [abs].
  151. Salem, A. K. and Chao, J. and Leong, K. W. and Searson, P. C., Receptor-mediated self-assembly of multi-component magnetic nanowires, Advanced Materials, vol. 16 no. 3 (2004), pp. 268-+ .
  152. Le Visage, C. and Dunham, B. and Flint, P. and Leong, K. W., Coculture of mesenchymal stem cells and respiratory epithelial cells to engineer a human composite respiratory mucosa, Tissue Engineering, vol. 10 no. 9-10 (2004), pp. 1426-1435 .
  153. Wen, J. and Mao, H. Q. and Li, W. P. and Lin, K. Y. and Leong, K. W., Biodegradable polyphosphoester micelles for gene delivery, Journal of Pharmaceutical Sciences, vol. 93 no. 8 (2004), pp. 2142-2157 .
  154. Chan, V. and Liu, K. K. and Le Visage, C. and Ju, B. F. and Leong, K. W., Bioadhesive characterization of poly(methylidene malonate 2.12) microparticle on model extracellular matrix, Biomaterials, vol. 25 no. 18 (2004), pp. 4327-4332 .
  155. Wang, J. and Sun, D. D. N. and Shin-ya, Y. and Leong, K. W., Stimuli-responsive hydrogel based on poly(propylene phosphate), Macromolecules, vol. 37 no. 2 (2004), pp. 670-672 .
  156. Huang, S. W. and Wang, J. and Zhang, P. C. and Mao, H. Q. and Zhuo, R. X. and Leong, K. W., Water-soluble and nonionic polyphosphoester: Synthesis, degradation, biocompatibility and enhancement of gene expression in mouse muscle, Biomacromolecules, vol. 5 no. 2 (2004), pp. 306-311 .
  157. Quek, C. H. and Li, J. and Sun, T. and Ling, M. and Chan, H. and Mao, H. Q. and Gan, L. M. and Leong, K. W. and Yu, H., Photo-crosslinkable microcapsules formed by polyelectrolyte copolymer and modified collagen for rat hepatocyte encapsulation, Biomaterials, vol. 25 no. 17 (2004), pp. 3531-3540 .
  158. Wang, J. and Gao, S. J. and Zhang, P. C. and Wang, S. and Mao, M. Q. and Leong, K. W., Polyphosphoramidate gene carriers: effect of charge group on gene transfer efficiency, Gene Therapy, vol. 11 no. 12 (2004), pp. 1001-1010 .
  159. Bini, T. B. and Gao, S. J. and Xu, X. Y. and Wang, S. and Ramakrishna, S. and Leong, K. W., Peripheral nerve regeneration by microbraided poly(L-lactide-co-glycolide) biodegradable polymer fibers, Journal of Biomedical Materials Research Part A, vol. 68A no. 2 (2004), pp. 286-295 .
  160. Wang, J. and Lee, I. L. and Lim, W. S. and Chia, S. M. and Yu, H. and Leong, K. W. and Mao, H. Q., Evaluation of collagen and methylated collagen as gene carriers, International Journal of Pharmaceutics, vol. 279 no. 1-2 (2004), pp. 115-126 .
  161. Wan, A. C. A. and Liao, I. C. and Yim, E. K. F. and Leong, K. W., Mechanism of fiber formation by interfacial polyelectrolyte complexation, Macromolecules, vol. 37 no. 18 (2004), pp. 7019-7025 .
  162. Li, Q. and Williams, C. G. and Sun, D. D. N. and Wang, J. and Leong, K. and Elisseeff, J. H., Photocrosslinkable polysaccharides based on chondroitin sulfate, Journal of Biomedical Materials Research Part A, vol. 68A no. 1 (2004), pp. 28-33 .
  163. Shin-Ya, Y. and Tsurushima, H. and Tsurumi, T. and Kajiuchi, T. and Leong, K. W., Polyelectrolyte complex films derived from polyethyleneoxide-maleic acid copolymer and chitosan: Preparation and characterization, Macromolecular Bioscience, vol. 4 no. 5 (2004), pp. 526-531 .
  164. Kiang, T. and Bright, C. and Cheung, C. Y. and Stayton, P. S. and Hoffman, A. S. and Leong, K. W., Formulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expression, Journal of Biomaterials Science-Polymer Edition, vol. 15 no. 11 (2004), pp. 1405-1421 .
  165. Kiang, T. and Wen, H. and Lim, H. W. and Leong, K. W., The effect of the degree of chitosan deacetylation on the efficiency of gene transfection, Biomaterials, vol. 25 no. 22 (2004), pp. 5293-5301 .
  166. Salem, A. K. and Chen, M. and Hayden, J. and Leong, K. W. and Searson, P. C., Directed assembly of multisegment Au/Pt/Au nanowires, Nano Letters, vol. 4 no. 6 (2004), pp. 1163-1165 .
  167. Le Visage, C. and Rioux-Leclercq, N. and Haller, M. and Breton, P. and Malavaud, B. and Leong, K., Efficacy of paclitaxel released from bio-adhesive polymer microspheres on model superficial bladder cancer, Journal of Urology, vol. 171 no. 3 (2004), pp. 1324-1329 .
  168. Wan, A. C. A. and Yim, E. K. F. and Liao, I. C. and Le Visage, C. and Leong, K. W., Encapsulation of biologics in self-assembled fibers as biostructural units for tissue engineering, Journal of Biomedical Materials Research Part A, vol. 71A no. 4 (2004), pp. 586-595 .
  169. Salem, A.K. and Min Chen and Hayden, J. and Leong, K.W. and Searson, P.C., Directed assembly of multisegment Au/Pt/Au nanowires, Nano Lett. (USA), vol. 4 no. 6 (2004), pp. 1163 - 5 [nl049462r]  [abs].
  170. Faranesh, A.Z. and Nastley, M.T. and de la Cruz, C.P. and Haller, M.F. and Laquerriere, P. and Leong, K.W. and McVeigh, E.R., In vitro release of vascular endothelial growth factor from gadolinium-doped biodegradable microspheres, Magn. Reson. Med. (USA), vol. 51 no. 6 (2004), pp. 1265 - 71 [mrm.20092]  [abs].
  171. Salem, A.K. and Searson, P.C. and Leong, K.W., Multifunctional nanorods for gene delivery, Nature Mater. (UK), vol. 2 no. 10 (2003), pp. 668 - 71 [nmat974]  [abs].
  172. Liu, X. M. and Yang, Y. Y. and Leong, K. W., Thermally responsive polymeric micellar nanoparticles self-assembled from cholesteryl end-capped random poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide): synthesis, temperature-sensitivity, and morphologies, Journal of Colloid and Interface Science, vol. 266 no. 2 (2003), pp. 295-303 .
  173. Li, J. and Li, X. and Ni, X. P. and Leong, K. W., Synthesis and characterization of new biodegradable amphiphilic poly(ethylene oxide)-b-poly[(R)-3-hydroxy butyratel-b-poly(ethylene oxide) triblock copolymers, Macromolecules, vol. 36 no. 8 (2003), pp. 2661-2667 .
  174. Lu, Hong-Fang and Lim, Wei Seng and Wang, Jun and Tang, Zhi-Qun and Zhang, Peng-Chi and Leong, Kam W. and Chia, Ser Mien and Yu, Hanry and Mao, Hai-Quan, Galactosylated PVDF membrane promotes hepatocyte attachment and functional maintenance, Biomaterials, vol. 24 no. 27 (2003), pp. 4893 - 4903 [S0142-9612(03)00404-6]  [abs].
  175. Li, Jun and Ni, Xiping and Zhou, Zhihan and Leong, Kam W., Preparation and characterization of polypseudorotaxanes based on block-selected inclusion complexation between poly(propylene oxide)-poly(ethylene oxide)-poly(propylene oxide) triblock copolymers and α-cyclodextrin, Journal of the American Chemical Society, vol. 125 no. 7 (2003), pp. 1788 - 1795 [ja026623p]  [abs].
  176. Chao Yin and Ser Mien Chia and Chai Hoon Quek and Hanry Yu and Ren-Xi Zhuo and Leong, K.W. and Hai-Quan Mao, Microcapsules with improved mechanical stability for hepatocyte culture, Biomaterials (UK), vol. 24 no. 10 (2003), pp. 1771 - 80 [S0142-9612(02)00580-X]  [abs].
  177. Li, Jun and Ni, Xiping and Leong, Kam W., Injectable drug-delivery systems based on supramolecular hydrogels formed by poly(ethylene oxide)s and α-cyclodextrin, Journal of Biomedical Materials Research - Part A, vol. 65 no. 2 (2003), pp. 196 - 202 [jbm.a.10444]  [abs].
  178. Xu, X. Y. and Yee, W. C. and Hwang, P. Y. K. and Yu, H. and Wan, A. C. A. and Gao, S. J. and Boon, K. L. and Mao, H. Q. and Leong, K. W. and Wang, S., Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits, Biomaterials, vol. 24 no. 13 (2003), pp. 2405-2412 .
  179. Li, Xu and Li, Jun and Leong, Kam W., Preparation and characterization of inclusion complexes of biodegradable amphiphilic poly(ethylene oxide)-poly[(R)-3-hydroxybutyrate]-poly(ethylene oxide) triblock copolymers with cyclodextrins, Macromolecules, vol. 36 no. 4 (2003), pp. 1209 - 1214 [ma0213347]  [abs].
  180. Yin, Chao and Ying, Lei and Zhang, Peng-Chi and Zhuo, Ren-Xi and Kang, En-Tang and Leong, Kam W. and Mao, Hai-Quan, High density of immobilized galactose ligand enhances hepatocyte attachment and function, Journal of Biomedical Materials Research - Part A, vol. 67 no. 4 (2003), pp. 1093 - 1104 [jbm.a.10033]  [abs].
  181. Li, Jun and Li, Xu and Ni, Xiping and Leong, Kam W., Synthesis and characterization of new biodegradable amphiphilic poly(ethylene oxide)-b-poly [(R)-3-hydroxy butyrate]-b-poly(ethylene oxide) triblock copolymers, Macromolecules, vol. 36 no. 8 (2003), pp. 2661 - 2667 [ma025725x]  [abs].
  182. Wen, J. and Kim, G. J. A. and Leong, K. W., Poly(D,Llactide-co-ethyl ethylene phosphate)s as new drug carriers, Journal of Controlled Release, vol. 92 no. 1-2 (2003), pp. 39-48 .
  183. Yin, C. and Chia, S. M. and Quek, C. H. and Yu, H. R. and Zhuo, R. X. and Leong, K. W. and Mao, H. Q., Microcapsules with improved mechanical stability for hepatocyte culture, Biomaterials, vol. 24 no. 10 (2003), pp. 1771-1780 .
  184. Xu, Xiaoyun and Yee, Woon-Chee and Hwang, Peter Y.K. and Yu, Hanry and Wan, Andrew C.A. and Gao, Shujun and Boon, Kum-Loong and Mao, Hai-Quan and Leong, Kam W. and Wang, Shu, Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits, Biomaterials, vol. 24 no. 13 (2003), pp. 2405 - 2412 [S0142-9612(03)00109-1]  [abs].
  185. Liu, Xue-Ming and Yang, Yi-Yan and Leong, Kam W., Thermally responsive polymeric micellar nanoparticles self-assembled from cholesteryl end-capped random poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide): Synthesis, temperature-sensitivity, and morphologies, Journal of Colloid and Interface Science, vol. 266 no. 2 (2003), pp. 295 - 303 [S0021-9797(03)00691-X]  [abs].
  186. Zhao, Zhong and Wang, Jun and Mao, Hai-Quan and Leong, Kam W., Polyphosphoesters in drug and gene delivery, Advanced Drug Delivery Reviews, vol. 55 no. 4 (2003), pp. 483 - 499 [S0169-409X(03)00040-1]  [abs].
  187. Ying, Lei and Yin, Chao and Zhuo, R.X. and Leong, K.W. and Mao, H.Q. and Kang, E.T. and Neoh, K.G., Immobilization of galactose ligands on acrylic acid graft-copolymerized poly(ethylene terephthalate) film and its application to hepatocyte culture, Biomacromolecules, vol. 4 no. 1 (2003), pp. 157 - 165 [bm025676w]  [abs].
  188. Fang, Ning and Wang, Jun and Mao, Hai-Quan and Leong, Kam W. and Chan, Vincent, BHEM-Chol/DOPE liposome induced perturbation of phospholipid bilayer, Colloids and Surfaces B: Biointerfaces, vol. 29 no. 4 (2003), pp. 233 - 245 [S0927-7765(02)00207-2]  [abs].
  189. Wen, Jie and Kim, Gloria J.A. and Leong, Kam W., Poly(D,Llactide-co-ethyl ethylene phosphate)s as new drug carriers, Journal of Controlled Release, vol. 92 no. 1-2 (2003), pp. 39 - 48 [S0168-3659(03)00294-3]  [abs].
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  191. Li, J. and Ni, X. P. and Leong, K. W., Injectable drug-delivery systems based on supramolecular hydrogels formed by poly(ethylene oxide) and alpha-cyclodextrin, Journal of Biomedical Materials Research Part A, vol. 65A no. 2 (2003), pp. 196-202 .
  192. Salem, A. K. and Searson, P. C. and Leong, K. W., Multifunctional nanorods for gene delivery, Nature Materials, vol. 2 no. 10 (2003), pp. 668-671 .
  193. Du, X. Y. and Yang, Y. S. and Le Visage, C. and Chen, H. H. and DeJong, R. and Qiu, B. S. and Wang, D. M. and Leong, K. W. and Hamper, U. M. and Yang, X. M., In vivo US monitoring of catheter-based vascular delivery of gene microspheres in pigs: Feasibility, Radiology, vol. 228 no. 2 (2003), pp. 555-559 .
  194. Chew, J. L. and Wolfowicz, C. B. and Mao, H. Q. and Leong, K. W. and Chua, K. Y., Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice, Vaccine, vol. 21 no. 21-22 (2003), pp. 2720-2729 .
  195. Lu, H. F. and Lim, W. S. and Wang, J. and Tang, Z. Q. and Zhang, P. C. and Leong, K. W. and Chia, S. M. and Yu, H. and Mao, H. Q., Galactosylated PVDF membrane promotes hepatocyte attachment and functional maintenance, Biomaterials, vol. 24 no. 27 (2003), pp. 4893-4903 .
  196. Ying, L. and Yin, C. and Zhuo, R. X. and Leong, K. W. and Mao, H. Q. and Kang, E. T. and Neoh, K. G., Immobilization of galactose ligands on acrylic acid graft-copolymerized poly(ethylene terephthalate) film and its application to hepatocyte culture, Biomacromolecules, vol. 4 no. 1 (2003), pp. 157-165 .
  197. Fang, N. and Wang, J. and Mao, H. Q. and Leong, K. W. and Chan, V., BHEM-Chol/DOPE liposome induced perturbation of phospholipid bilayer, Colloids and Surfaces B-Biointerfaces, vol. 29 no. 4 (2003), pp. 233-245 .
  198. Zhao, Z. and Wang, J. and Mao, H. Q. and Leong, K. W., Polyphosphoesters in drug and gene delivery, Advanced Drug Delivery Reviews, vol. 55 no. 4 (2003), pp. 483-499 .
  199. Shi, L. and Tang, G. P. and Gao, S. J. and Ma, Y. X. and Liu, B. H. and Li, Y. and Zeng, J. M. and Ng, Y. K. and Leong, K. W. and Wang, S., Repeated intrathecal administration of plasmid DNA complexed with polyethylene glycol-grafted polyethylenimine led to prolonged transgene expression in the spinal cord, Gene Therapy, vol. 10 no. 14 (2003), pp. 1179-1188 .
  200. Li, X. and Li, J. and Leong, K. W., Preparation and characterization of inclusion complexes of biodegradable amphiphilic poly(ethylene oxide)-poly[(R)-3-hydroxybutyrate]-poly(ethylene oxide) triblock copolymers with cyclodextrins, Macromolecules, vol. 36 no. 4 (2003), pp. 1209-1214 .
  201. Li, J. and Ni, X. P. and Leong, K., Block-selected molecular recognition and formation of polypseudorotaxanes between poly(propylene oxide)-poly (ethylene oxide)poly(propylene oxide) triblock copolymers and alpha-cyclodextrin, Angewandte Chemie-International Edition, vol. 42 no. 1 (2003), pp. 69-72 .
  202. Wang, J. and Huang, S. W. and Zhang, P. C. and Mao, H. Q. and Leong, K. W., Effect of side-chain structures on gene transfer efficiency of biodegradable cationic polyphosphoesters, International Journal of Pharmaceutics, vol. 265 no. 1-2 (2003), pp. 75-84 .
  203. Yin, C. and Ying, L. and Zhang, P. C. and Zhuo, R. X. and Kang, E. T. and Leong, K. W. and Mao, H. Q., High density of immobilized galactose ligand enhances hepatocyte attachment and function, Journal of Biomedical Materials Research Part A, vol. 67A no. 4 (2003), pp. 1093-1104 .
  204. Sun, T. and Chan, M. L. H. and Zhou, Y. and Xu, X. and Zhang, J. and Lao, X. J. and Wang, X. W. and Quek, C. H. and Chen, J. P. and Leong, K. W. and Yu, H., Use of ultrathin shell microcapsules of hepatocytes in bioartificial liver-assist device, Tissue Engineering, vol. 9 (2003), pp. S65-S75 .
  205. Li, J. and Ni, X. P. and Zhou, Z. H. and Leong, K. W., Preparation and characterization of polypseudorotaxanes based on block-selected inclusion complexation between poly(propylene oxide)-poly(ethylene oxide)-poly(propylene oxide) triblock copolymers and alpha-cyclodextrin, Journal of the American Chemical Society, vol. 125 no. 7 (2003), pp. 1788-1795 .
  206. Yin, C. and Liao, K. and Mao, H. Q. and Leong, K. W. and Zhuo, R. X. and Chan, V., Adhesion contact dynamics of HepG2 cells on galactose-immobilized substrates, Biomaterials, vol. 24 no. 5 (2003), pp. 837-850 .
  207. Xiangying Du and Yuesong Yang and Le Visage, C. and Chen, H.H. and DeJong, R. and Bensheng Qiu and Danming Wang and Leong, K.W. and Hamper, U.M. and Xiaoming Yang, Microsphere as a contrast agent/gene vector in ultrasound imaging-based vascular gene delivery, 2002 IEEE International Symposium on Biomedical Imaging (Cat. No.02EX608) (2002), pp. 989 - 92 [ISBI.2002.1029429]  [abs].
  208. Chia, S.M. and Wan, A.C.A. and Quek, C.H. and Mao, H.Q. and Xu, X. and Shen, L. and Ng, M.L. and Leong, K.W. and Yu, H., Multi-layered microcapsules for cell encapsulation, Biomaterials, vol. 23 no. 3 (2002), pp. 849 - 856 [S0142-9612(01)00191-0]  [abs].
  209. Chia, Ser-Mien and Zhou, Yi and Sun, Tao and Mao, Hai-Quan and Leong, Kam W. and Chen, Jia-Ping and Yu, Hanry, Issues and technologies leading to a new bio-artificial liver with microencapsulated hepatocytes, Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products (2002), pp. 71 -  [abs].
  210. Chen, H.H. and Le Visage, C. and Bensheng Qiu and Xiangying Du and Ouwerkerk, R. and Leong, K.W. and Xiaoming Yang, Novel method for imaging biodegradable polymeric microparticles using MRI: application toward monitoring drug delivery, 2002 IEEE International Symposium on Biomedical Imaging (Cat. No.02EX608) (2002), pp. 145 - 8 [ISBI.2002.1029214]  [abs].
  211. Xu, Xiaoyun and Yu, Hanry and Gao, Shujun and Mao, Hai-Quan and Leong, Kam W. and Wang, Shu, Polyphosphoester microspheres for sustained release of biologically active nerve growth factor, Biomaterials, vol. 23 no. 17 (2002), pp. 3765 - 3772 [S0142-9612(02)00116-3]  [abs].
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  213. Chen, H.H. and Le Visage, C. and Qiu, B. and Du, X. and Ouwerkerk, R. and Leong, K.W. and Yang, X., Novel method for imaging biodegradable polymeric microparticles using MRI: application toward monitoring drug delivery, 2002 IEEE International Symposium on Biomedical Imaging (2002), pp. 4 pp. -  [abs].
  214. Chia, S. M. and Wan, A. C. A. and Quek, C. H. and Mao, H. Q. and Xu, X. and Shen, L. and Ng, M. L. and Leong, K. W. and Yu, H., Multi-layered microcapsules for cell encapsulation, Biomaterials, vol. 23 no. 3 (2002), pp. 849-856 .
  215. Wang, J. and Zhang, P. C. and Lu, H. F. and Ma, N. and Wang, S. and Mao, H. Q. and Leong, K. W., New polyphosphoramidate with a spermidine side chain as a gene carrier, Journal of Controlled Release, vol. 83 no. 1 (2002), pp. 157-168 .
  216. Chew, J. L. and Fu, T. Q. H. and Mao, H. Q. and Leong, K. W. and Chua, K. Y., Oral administration of major house dust mite allergen genes complexed with chitosan elicits protective Th1-skewed immunity in mice, Allergy, vol. 57 (2002), pp. 64-64 .
  217. Fang, N. and Chan, V. and Wan, K. T. and Mao, H. Q. and Leong, K. W., Colloidal adhesion of phospholipid vesicles: high-resolution reflection interference contrast microscopy and theory, Colloids and Surfaces B-Biointerfaces, vol. 25 no. 4 (2002), pp. 347-362 .
  218. Xu, X. Y. and Yu, H. and Gao, S. J. and Mao, H. Q. and Leong, K. W. and Wang, S., Polyphosphoester microspheres for sustained release of biologically active nerve growth factor, Biomaterials, vol. 23 no. 17 (2002), pp. 3765-3772 .
  219. Wang, J. and Zhang, P. C. and Mao, H. Q. and Leong, K. W., Enhanced gene expression in mouse muscle by sustained release of plasmid DNA using PPE-EA as a carrier, Gene Therapy, vol. 9 no. 18 (2002), pp. 1254-1261 .
  220. Kumar, M. and Behera, A. K. and Lockey, R. F. and Zhang, J. and Bhullar, G. and De La Cruz, C. P. and Chen, L. C. and Leong, K. W. and Huang, S. K. and Mohapatra, S. S., Intranasal gene transfer by chitosan-DNA nanospheres protects BALB/c mice against acute respiratory syncytial virus infection, Human Gene Therapy, vol. 13 no. 12 (2002), pp. 1415-1425 .
  221. Peng, B. G. and Liu, S. Q. and Kuang, M. and He, Q. and Totsuka, S. and Huang, L. and Huang, J. F. and Lu, M. D. and Liang, L. J. and Leong, K. W. and Ohno, T., Autologous fixed tumor vaccine: A formulation with cytokine-microparticles for protective immunity against recurrence of human hepatocellular carcinoma, Japanese Journal of Cancer Research, vol. 93 no. 4 (2002), pp. 363-368 .
  222. Ning Fang and Chan, V. and Kai-Tak Wan and Hai-Quan Mao and Leong, K.W., Colloidal adhesion of phospholipid vesicles: high-resolution reflection interference contrast microscopy and theory, Colloids Surf. B, Biointerfaces (Netherlands), vol. 25 no. 4 (2002), pp. 347 - 62 [S0927-7765(01)00336-8]  [abs].
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  225. Li, Jun and Li, Xu and Toh, Kee Chua and Ni, Xiping and Zhou, Zhihan and Leong, Kam W., Inclusion complexation and formation of polypseudorotaxanes between poly[(ethylene oxide)-ran-(propylene oxide)] and cyclodextrins, Macromolecules, vol. 34 no. 26 (2001), pp. 8829 - 8831 [ma011129b]  [abs].
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  227. Ramakrishna, S. and Mayer, J. and Wintermantel, E. and Leong, K.W., Biomedical applications of polymer-composite materials: A review, Compos. Sci. Technol. (UK), vol. 61 no. 9 (2001), pp. 1189 - 224 [S0266-3538(00)00241-4]  [abs].
  228. Hanes, J. and Sills, A. and Zhao, Z. and Suh, K. W. and Tyler, B. and DiMeco, F. and Brat, D. J. and Choti, M. A. and Leong, K. W. and Pardoll, D. M. and Brem, H., Controlled local delivery of interleukin-2 by biodegradable polymers protects animals from experimental brain tumors and liver tumors, Pharmaceutical Research, vol. 18 no. 7 (2001), pp. 899-906 .
  229. Chan, Vincent and Mao, Hai-Quan and Leong, Kam W., Chitosan-induced perturbation of dipalmitoyl-sn-glycero-3-phosphocholine membrane bilayer, Langmuir, vol. 17 no. 12 (2001), pp. 3749 - 3756 [la001754u]  [abs].
  230. Wang, S. and Ma, N. and Gao, S. J. and Yu, H. and Leong, K. W., Transgene expression in the brain stem effected by intramuscular injection of polyethylenimine/DNA complexes, Molecular Therapy, vol. 3 no. 5 (2001), pp. 658-664 .
  231. Li, J. and Li, X. and Zhou, Z. H. and Ni, X. P. and Leong, K. W., Formation of supramolecular hydrogels induced by inclusion complexation between pluronics and alpha-cyclodextrin, Macromolecules, vol. 34 no. 21 (2001), pp. 7236-7237 .
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  233. Chan, V. and Mao, H. Q. and Leong, K. W., Chitosan-induced perturbation of dipalmitoyl-sn-glycero-3-phosphocholine membrane bilayer, Langmuir, vol. 17 no. 12 (2001), pp. 3749-3756 .
  234. Mao, H. Q. and Roy, K. and Troung-Le, V. L. and Janes, K. A. and Lin, K. Y. and Wang, Y. and August, J. T. and Leong, K. W., Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency, Journal of Controlled Release, vol. 70 no. 3 (2001), pp. 399-421 .
  235. Wang, S. and Wan, A. C. A. and Xu, X. Y. and Gao, S. J. and Mao, H. Q. and Leong, K. W. and Yu, H., A new nerve guide conduit material composed of a biodegradable poly(phosphoester), Biomaterials, vol. 22 no. 10 (2001), pp. 1157-1169 .
  236. Wang, J. and Mao, H. Q. and Leong, K. W., A novel biodegradable gene carrier based on polyphosphoester, Journal of the American Chemical Society, vol. 123 no. 38 (2001), pp. 9480-9481 .
  237. Fang, N. and Chan, V. and Mao, H. Q. and Leong, K. W., Interactions of phospholipid bilayer with chitosan: effect of molecular weight and pH, Biomacromolecules, vol. 2 no. 4 (2001), pp. 1161-1168 .
  238. Li, J. and Li, X. and Toh, K. C. and Ni, X. P. and Zhou, Z. H. and Leong, K. W., Inclusion complexation and formation of polypseudorotaxanes between poly[(ethylene oxide)-ran-(propylene oxide)] and cyclodextrins, Macromolecules, vol. 34 no. 26 (2001), pp. 8829-8831 .
  239. Georgantas, R. W. and Leong, K. W. and August, J. T., Antigen-specific induction of peripheral T cell tolerance in vivo by codelivery of DNA vectors encoding antigen and Fas ligand, Human Gene Therapy, vol. 11 no. 6 (2000), pp. 851-858 .
  240. Chia, S. M. and Leong, K. W. and Li, J. and Xu, X. and Zeng, K. Y. and Er, P. N. and Gao, S. J. and Yu, H., Hepatocyte encapsulation for enhanced cellular functions, Tissue Engineering, vol. 6 no. 5 (2000), pp. 481-495 .
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  242. Kalyanasundaram, S. and Feinstein, S. and Nicholson, J. P. and Leong, K. W. and Garver, R. I., Coacervate microspheres as carriers of recombinant adenoviruses, Cancer Gene Therapy, vol. 6 no. 2 (1999), pp. 107-112 .
  243. Truong-Le, V. L. and Walsh, S. M. and Schweibert, E. and Mao, H. Q. and Guggino, W. B. and August, J. T. and Leong, K. W., Gene transfer by DNA-gelatin nanospheres, Archives of Biochemistry and Biophysics, vol. 361 no. 1 (1999), pp. 47-56 .
  244. Roy, K. and Mao, H. Q. and Huang, S. K. and Leong, K. W., Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy, Nature Medicine, vol. 5 no. 4 (1999), pp. 387-391 .
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  248. Brown, K. E. and Leong, K. and Huang, C. H. and Dalal, R. and Green, G. D. and Haimes, H. B. and Jimenez, P. A. and Bathon, J., Gelatin/chondroitin 6-sulfate microspheres for the delivery of therapeutic proteins to the joint, Arthritis and Rheumatism, vol. 41 no. 12 (1998), pp. 2185-2195 .
  249. Hu, W. P. and Wang, L. F. and Leong, K. W., Synthesis and characterization of methacrylic derivatives as drug carriers, Drug Development and Industrial Pharmacy, vol. 23 no. 7 (1997), pp. 671-678 .
  250. Kalyanasundaram, S. and Leong, K. W., Intracranial drug delivery systems, Stp Pharma Sciences, vol. 7 no. 1 (1997), pp. 62-70 .
  251. Kalyanasundaram, S. and Calhoun, V. D. and Leong, K. W., A finite element model for predicting the distribution of drugs delivered intracranially to the brain, American Journal of Physiology-Regulatory Integrative and Comparative Physiology, vol. 42 no. 5 (1997), pp. R1810-R1821 .
  252. Kalyanasundaram, S. and Feinstein, S. and Nicholson, J. P. and Leong, K. W. and Garver, R. I., Recombinant adenovirus can be encapsulated and released from coacervate microspheres in a time-dependent fashion, Cancer Gene Therapy, vol. 4 no. 6 (1997), pp. O40-O40 .
  253. Lo, H. and Kadiyala, S. and Guggino, S. E. and Leong, K. W., Poly(L-lactic acid) foams with cell seeding and controlled-release capacity, Journal of Biomedical Materials Research, vol. 30 no. 4 (1996), pp. 475-484 .
  254. Gutsche, Annie Tang and Lo, Hungnan and Zurlo, Joanne and Yager, James and Leong, Kam W., Engineering of a sugar-derivatized porous network for hepatocyte culture, Biomaterials, vol. 17 no. 3 (1996), pp. 387 - 393 [0142-9612(96)85577-3]  [abs].
  255. Kadiyala, S. and Lo, H. and Ponticiello, M.S. and Reddi, A.H. and Leong, K.W., Bone induction achieved by controlled release of BMP from PLA/hydroxyapatite foams, Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium, vol. 1 (1996), pp. 289 -  [abs].
  256. Lo, H. and Kadiyala, S. and Guggino, S.E. and Leong, K.W., Poly(L-lactic acid) foams with cell seeding and controlled-release capacity, Journal of Biomedical Materials Research, vol. 30 no. 4 (1996), pp. 475 - 484 [(SICI)1097-4636(199604)30:4<475::AID-JBM5>3.0.CO;2-M]  [abs].
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  258. Lesser, G. J. and Grossman, S. A. and Leong, K. W. and Lo, H. N. and Eller, S., In vitro and in vivo studies of subcutaneous hydromorphone implants designed for the treatment of cancer pain, Pain, vol. 65 no. 2-3 (1996), pp. 265-272 .
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  260. Zhao, Z. and Leong, K. W., Controlled delivery of antigens and adjuvants in vaccine development, Journal of Pharmaceutical Sciences, vol. 85 no. 12 (1996), pp. 1261-1270 .
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  267. Shao, Wen and Leong, Kam W., Enzymatically degradable synthetic polymers, Materials Research Society Symposium - Proceedings, vol. 394 (1995), pp. 199 - 204  [abs].
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  274. Gutsche, A.T. and Parsons-Wingerter, P. and Chand, D. and Saltzman, W.M. and Leong, K.W., N-acetylglucosamine and adenosine derivatized surfaces for cell culture: 3T3 fibroblast and chicken hepatocyte response, Biotechnology and Bioengineering, vol. 43 no. 8 (1994), pp. 801 - 809  [abs].
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  276. Tang Gutsche, Annie and Zurlo, Joanne and Lo, Hungnan and Leong, Kam W., Synthesis and characterization of polymer substrates for rat hepatocyte culture, Materials Research Society Symposium - Proceedings, vol. 330 (1994), pp. 243 - 248  [abs].
  277. Lin, Steve T. and Krebs, Steve L. and Kadiyala, Sudha and Leong, Kam W. and LaCourse, William C. and Kumar, Binod, Development of bioabsorbable glass fibres, Biomaterials, vol. 15 no. 13 (1994), pp. 1057 - 1061 [0142-9612(94)90091-4]  [abs].
  278. Lin, S. T. and Krebs, S. L. and Kadiyala, S. and Leong, K. W. and Lacourse, W. C. and Kumar, B., Development of Bioabsorbable Glass-Fibers, Biomaterials, vol. 15 no. 13 (1994), pp. 1057-1061 .
  279. Uppal, P. and Jampel, H. D. and Quigley, H. A. and Leong, K. W., Pharmacokinetics of Etoposide Delivery by a Bioerodible Drug Carrier Implanted at Glaucoma Surgery, Journal of Ocular Pharmacology, vol. 10 no. 2 (1994), pp. 471-479 .
  280. Gutsche, A. T. and Parsonswingerter, P. and Chand, D. and Saltzman, W. M. and Leong, K. W., N-Acetylglucosamine and Adenosine Derivatized Surfaces for Cell-Culture - 3t3 Fibroblast and Chicken Hepatocyte Response, Biotechnology and Bioengineering, vol. 43 no. 8 (1994), pp. 801-809 .
  281. Kalyanasundaram, S. and Calhoun, V. D. and Leong, K. W., Coupled Convective-Diffusive Mass-Transport in the Brain, Faseb Journal, vol. 8 no. 4 (1994), pp. A14-A14 .
  282. Golumbek, P. T. and Azhari, R. and Jaffee, E. M. and Levitsky, H. I. and Lazenby, A. and Leong, K. and Pardoll, D. M., Controlled-Release, Biodegradable Cytokine Depots - a New Approach in Cancer Vaccine Design, Cancer Research, vol. 53 no. 24 (1993), pp. 5841-5844 .
  283. Dahiyat, B. I. and Hostin, E. and Posadas, E. M. and Leong, K. W., Synthesis and Characterization of Putrescine-Based Poly(Phosphoester-Urethanes), Journal of Biomaterials Science-Polymer Edition, vol. 4 no. 5 (1993), pp. 529-543 .
  284. Leong, K. W. and Truong, V. L., P-Glycoprotein-Specific Binding of Immuno-Microspheres to Drug-Resistant Kb-V-1 Cells, Faseb Journal, vol. 7 no. 4 (1993), pp. A690-A690 .
  285. Jampel, H. D. and Thibault, D. and Leong, K. W. and Uppal, P. and Quigley, H. A., Glaucoma Filtration Surgery in Nonhuman-Primates Using Taxol and Etoposide in Polyanhydride Carriers, Investigative Ophthalmology & Visual Science, vol. 34 no. 11 (1993), pp. 3076-3083 .
  286. Reisfeld, B. and Blackband, S. and Calhoun, V. and Grossman, S. and Eller, S. and Leong, K., The Use of Magnetic-Resonance-Imaging to Track Controlled Drug Release and Transport in the Brain, Magnetic Resonance Imaging, vol. 11 no. 2 (1993), pp. 247-252 .
  287. Heffez, D. S. and Leong, K. W., Sustained-Release of Papaverine for the Treatment of Cerebral Vasospasm - Invitro Evaluation of Release Kinetics and Biological-Activity, Journal of Neurosurgery, vol. 77 no. 5 (1992), pp. 783-787 .
  288. Richards, M. and Dahiyat, B.I. and Arm, D.M. and Lin, S. and Leong, K.W., Interfacial polycondensation and characterization of polyphosphates and polyphosphonates, Journal of Polymer Science, Part A: Polymer Chemistry, vol. 29 no. 8 (1991), pp. 1157 - 1165 [pola.1991.080290809]  [abs].
  289. Jampel, H. D. and Koya, P. and Leong, K. and Quigley, H. A., Invitro Release of Hydrophobic Drugs from Polyanhydride Disks, Ophthalmic Surgery and Lasers, vol. 22 no. 11 (1991), pp. 676-680 .
  290. Saltzman, W. M. and Parsonswingerter, P. and Leong, K. W. and Lin, S., Fibroblast and Hepatocyte Behavior on Synthetic-Polymer Surfaces, Journal of Biomedical Materials Research, vol. 25 no. 6 (1991), pp. 741-759 .
  291. Richards, M. and Dahiyat, B.I. and Arm, D.M. and Brown, P.R. and Leong, K.W., Evaluation of polyphosphates and polyphosphonates as degradable biomaterials, Journal of Biomedical Materials Research, vol. 25 no. 9 (1991), pp. 1151 - 1167  [abs].
  292. Saltzman, W. Mark and Parsons-Wingerter, Patricia and Leong, Kam W. and Lin, Shin, Fibroblast and hepatocyte behavior on synthetic polymer surfaces, Journal of Biomedical Materials Research, vol. 25 no. 6 (1991), pp. 741 - 759  [abs].
  293. Richards, M. and Dahiyat, B. I. and Arm, D. M. and Brown, P. R. and Leong, K. W., Evaluation of Polyphosphates and Polyphosphonates as Degradable Biomaterials, Journal of Biomedical Materials Research, vol. 25 no. 9 (1991), pp. 1151-1167 .
  294. Charles, J. B. and Ganthier, R. and Wilson, M. R. and Lee, D. A. and Baker, R. S. and Leong, K. W. and Glasgow, B. J., Use of Bioerodible Polymers Impregnated with Mitomycin in Glaucoma Filtration Surgery in Rabbits, Ophthalmology, vol. 98 no. 4 (1991), pp. 503-508 .
  295. Koya, P. and Jampel, H. and Quigley, H. and Leong, K., Pharmacokinetics of Vp-16 Release from Polyanhydrides after Experimental Filtration Surgery, Investigative Ophthalmology & Visual Science, vol. 32 no. 4 (1991), pp. 745-745 .
  296. Shi, F. Y. and Wang, L. F. and Tashev, E. and Leong, K. W., Synthesis and Characterization of Hydrolytically Labile Poly(Phosphoester Urethanes), Acs Symposium Series, vol. 469 (1991), pp. 141-154 .
  297. Lewis, H. and Schwartz, S. and Lee, D. and Leong, K., The Use of Bioerodible Polymer and 5-Fluorouracil in the Treatment of Experimental Proliferative Vitreoretinopathy, Investigative Ophthalmology & Visual Science, vol. 32 no. 4 (1991), pp. 1047-1047 .
  298. Richards, M. and Dahiyat, B. I. and Arm, D. M. and Lin, S. and Leong, K. W., Interfacial Polycondensation and Characterization of Polyphosphates and Polyphosphonates, Journal of Polymer Science Part a-Polymer Chemistry, vol. 29 no. 8 (1991), pp. 1157-1165 .
  299. Shi, F.Y. and Wang, L.F. and Leong, K.W., Synthesis and characterization of hydrolytically labile polyurethanes, Polymer Preprints, Division of Polymer Chemistry, American Chemical Society, vol. 31 no. 2 (1990), pp. 177 -  [abs].
  300. Tashev, E. and Shi, F.Y. and Leong, K.W., Potential applications of poly(phosphoester-urethanes) in controlled drug delivery, Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering, vol. 63 (1990), pp. 43 - 46  [abs].
  301. Jampel, H. D. and Leong, K. W. and Dunkelburger, G. R. and Quigley, H. A., Glaucoma Filtration Surgery in Monkeys Using 5-Fluorouridine in Polyanhydride Disks, Archives of Ophthalmology, vol. 108 no. 3 (1990), pp. 430-435 .
  302. Wong, Ngai C. and Leong, K. W. and Shapiro, Jeffrey H., Nonclassical intensity correlation from a type I phase matched optical parametric oscillator (1990), pp. 68 - 70  [abs].
  303. Leong, Kam W., Poly(phosphoesters) as biomaterials, Polymer Preprints, Division of Polymer Chemistry, American Chemical Society, vol. 31 no. 1 (1990), pp. 251 -  [abs].
  304. Tamargo, R. J. and Leong, K. W. and Brem, H., Growth-Inhibition of the 9l Glioma Using Polymers to Release Heparin and Cortisone-Acetate, Journal of Neuro-Oncology, vol. 9 no. 2 (1990), pp. 131-138 .
  305. Brem, H. and Kader, A. and Epstein, J. I. and Tamargo, R. J. and Domb, A. and Langer, R. and Leong, K. W., Biocompatibility of a Biodegradable, Controlled-Release Polymer in the Rabbit Brain, Selective Cancer Therapeutics, vol. 5 no. 2 (1989), pp. 55-65 .
  306. Kost, J. and Leong, K. and Langer, R., Ultrasound-Enhanced Polymer Degradation and Release of Incorporated Substances - (Controlled Release Drug Delivery Systems), Proceedings of the National Academy of Sciences of the United States of America, vol. 86 no. 20 (1989), pp. 7663-7666 .
  307. Kost, J. and Leong, K. and Langer, R., Ultrasonically Controlled Polymeric Drug Delivery, Makromolekulare Chemie-Macromolecular Symposia, vol. 19 (1988), pp. 275-285 .
  308. Bindschaedler, C. and Leong, K. and Mathiowitz, E. and Langer, R., Polyanhydride Microsphere Formulation by Solvent-Extraction, Journal of Pharmaceutical Sciences, vol. 77 no. 8 (1988), pp. 696-698 .
  309. Lee, D. A. and Leong, K. W. and Panek, W. C. and Eng, C. T. and Glasgow, B. J., The Use of Bioerodible Polymers and 5-Fluorouracil in Glaucoma Filtration Surgery, Investigative Ophthalmology & Visual Science, vol. 29 no. 11 (1988), pp. 1692-1697 .
  310. Lee, D. A. and Flores, R. A. and Anderson, P. J. and Leong, K. W. and Teekhasaenee, C. and Dekater, A. W. and Hertzmark, E., Glaucoma Filtration Surgery in Rabbits Using Bioerodible Polymers and 5-Fluorouracil, Ophthalmology, vol. 94 no. 12 (1987), pp. 1523-1530 .
  311. Leong, K. W. and Simonte, V. and Langer, R., Synthesis of Polyanhydrides - Melt-Polycondensation, Dehydrochlorination, and Dehydrative Coupling, Macromolecules, vol. 20 no. 4 (1987), pp. 705-712 .
  312. Leong, K. W. and D'Amore, P. and Marletta, M. and Langer, R., BIOERODIBLE POLYANHYDRIDES AS DRUG-CARRIER MATRICES. II. BIOCOMPATIBILITY AND CHEMICAL REACTIVITY., Journal of Biomedical Materials Research, vol. 20 no. 1 (1986), pp. 51 - 64  [abs].
  313. Leong, K. W. and Damore, P. and Marletta, M. and Langer, R., Bioerodible Polyanhydrides as Drug-Carrier Matrices .2. Biocompatibility and Chemical-Reactivity, Journal of Biomedical Materials Research, vol. 20 no. 1 (1986), pp. 51-64 .
  314. Leong, K. W. and Kost, J. and Mathiowitz, E. and Langer, R., Polyanhydrides for Controlled Release of Bioactive Agents, Biomaterials, vol. 7 no. 5 (1986), pp. 364-371 .
  315. Langer, R. and Siegel, R. and Brown, L. and Leong, K. and Kost, J. and Edelman, E., Controlled Release - 3 Mechanisms, Chemtech, vol. 16 no. 2 (1986), pp. 108-110 .
  316. Leong, K. W. and Brott, B. C. and Langer, R., BIOERODIBLE POLYANHYDRIDES AS DRUG-CARRIER MATRICES. I: CHARACTERIZATION, DEGRADATION, AND RELEASE CHARACTERISTICS., Journal of Biomedical Materials Research, vol. 19 no. 8 (1985), pp. 941 - 955  [abs].
  317. Leong, K. W. and Brott, B. C. and Langer, R., Bioerodible Polyanhydrides as Drug-Carrier Matrices .1. Characterization, Degradation, and Release Characteristics, Journal of Biomedical Materials Research, vol. 19 no. 8 (1985), pp. 941-955 .
  318. Langer, R. and Siegel, R. and Brown, L. and Leong, K. and Kost, J. and Edelman, E., Controlled Release and Magnetically Modulated Systems for Macromolecular Drugs, Annals of the New York Academy of Sciences, vol. 446 (1985), pp. 1-13 .
  319. Leong, K. W. and Brott, B. C. and Langer, R., BIOERODIBLE POLYANHYDRIDES AS A DRUG CARRIER MATRIX., Polymer Preprints, Division of Polymer Chemistry, American Chemical Society, vol. 25 no. 1 (1984), pp. 201 - 202 .
  320. Leong, K. and Forsman, W. C. and Vogel, F. L., Conversion of Carbon Graphite Fibers to Fibers of Graphite Oxide, Materials Science and Engineering, vol. 64 no. 2 (1984), pp. 149-155 .
  321. Leong, K. and Forsman, W. C., Electron-Transfer to Protons in Graphite-Intercalation, Synthetic Metals, vol. 6 no. 1 (1983), pp. 61-63 .
  322. Leong, K. and Tome, A. and Dziemianowicz, T. and Forsman, W., Intercalation of Transition-Metal Dichlorides with No as Coreagent, Synthetic Metals, vol. 7 no. 1-2 (1983), pp. 141-141 .
  323. Forsman, W. C. and Dziemianowicz, T. and Leong, K. and Carl, D., Graphite-Intercalation Chemistry - an Interpretive Review, Synthetic Metals, vol. 5 no. 2 (1983), pp. 77-100 .
  324. Leong, K. and Forsman, W. C. and Vogel, F. L., Intercalation of Graphite with the Adducts of Nitrosyl Chloride and Metal Chlorides, Carbon, vol. 20 no. 2 (1982), pp. 135-135 .
  325. Leong, K. and Forsman, W. C., Vapor-Phase Intercalation by Alcl3-Hcl Mixtures, Carbon, vol. 20 no. 2 (1982), pp. 132-132 .
  326. Yim, E.K.F. and Reano, R.M. and Pang, S.W. and Yee, A.F. and Chen, C.S. and Leong, K.W., Nanopattern-induced changes in morphology and motility of smooth muscle cells, Biomaterials (UK), vol. 26 no. 26 , pp. 5405 - 13 [058]  [abs].