Dr. You's research interest focus on computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.

Contact Info:

Office Location:	2345 CIEMAS
Office Phone:	(919) 660-8408
Email Address:
Web Page:	www.duke.edu/~you

Teaching (Fall 2009):

• BME 265.07, ADVANCED TOPICS

  Hudson 201, TuTh 02:50 PM-04:05 PM

• BME 100L.001, MODELS CELL & MOL SYSTEMS Synopsis

• BME 100L.01L, MODELS CELL & MOL SYSTEMS

  Teer P013, M 01:15 PM-03:15 PM

• BME 100L.02L, MODELS CELL & MOL SYSTEMS

  Teer P013, M 04:25 PM-06:25 PM

Education:

PhD, University of Wisconsin, 2002

MS, USTC-China, 1997

BE, Chengdu University, 1994

Specialties:

Genomics
Computational Biology
Nonlinear Dynamics

Research Interests:

Dr. You's research interest focus on computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.

Curriculum Vitae

Awards, Honors, and Distinctions

Packard Fellowship, November, 2006

Recent Publications

1. Y. Tanouchi and D. Tu and J. Kim and L. You, Noise Reduction by Diffusional Dissipation in a Minimal Quorum Sensing Motif, Plos Computational Biology, vol. 4 no. 8 (August, 2008)  [abs].
2. L. You and J. Yin, Evolutionary design on a budget: robustness and optimality of bacteriophage T7, Iee Proceedings Systems Biology, vol. 153 no. 2 (March, 2006), pp. 46 -- 52  [abs].
3. R. Srivastava and L. You and J. Summers and J. Yin, Stochastic vs. deterministic modeling of intracellular viral kinetics, Journal Of Theoretical Biology, vol. 218 no. 3 (October, 2002), pp. 309 -- 321  [abs].
4. D. Endy and L. You and I. J. Molineux and J. Yin, Prediction, design, and characterization of alternate genetic element orders for bacteriophage T7., Abstracts Of Papers Of The American Chemical Society, vol. 217 (March, 1999), pp. U205 -- U205 .
5. L. You and F. H. Arnold, Directed evolution of subtilisin E in Bacillus subtilis to enhance total activity in aqueous dimethylformamide, Protein Engineering, vol. 9 no. 1 (January, 1996), pp. 77 -- 83  [abs].