Papers Published

1. Henriquez, C.S. and Trayanova, N. and Plonsey, R., Potential and current distributions in a cylindrical bundle of cardiac tissue, Biophys. J. (USA), vol. 53 no. 6 (1988), pp. 907 - 18 .
   (last updated on 2007/04/16)

   Abstract:
   The intracellular and interstitial potentials associated with each cell or fiber in multicellular preparations carrying a uniformly propagating wave are important for characterizing the electrophysiological behavior of the preparation and in particular, for evaluating the source contributed by each fiber. The aforementioned potentials depend on a number of factors including the conductivities characterizing the intracellular, interstitial, and extracellular domains, the thickness of the tissue, and the distance (depth) of the field point from the surface of the tissue. A model study is presented describing the extracellular and interstitial potential distribution and current flow in a cylindrical bundle of cardiac muscle arising from a planar wavefront. For simplicity, the bundle is considered as a bidomain. Using typical values of conductivity, the results show that the intracellular and interstitial potential of fibers near the center of a very large bundle (>10 mm) may be approximated by the potentials of a single fiber surrounded by a limited extracellular space (a fiber in oil), hence justifying a core-conductor model

   Keywords:
   bioelectric phenomena;cardiology;muscle;