Papers Published

1. Barr, R.C. and Plonsey, R., Repolarizing stimuli followed by calcium transmembrane currents, 1995 IEEE Engineering in Medicine and Biology 17th Annual Conference and 21 Canadian Medical and Biological Engineering Conference (Cat. No.95CH35746), vol. vol.1 (1997), pp. 15 - 16 [IEMBS.1995.574977] .
   (last updated on 2007/04/12)

   Abstract:
   Repolarizing stimuli applied during the plateau phase of a cardiac action potential do not always cause the membrane to return to a resting state. Instead, the repolarizing stimulus may be followed immediately by a subsequent action potential. The subsequent action potential occurs even though the repolarizing stimulus returns the transmembrane potential to its resting level. This study used the Di Francesco-Noble membrane model in a patch geometry to evaluate the membrane currents that initiated the subsequent action potential. These initiating currents were found to be predominently calcium currents

   Keywords:
   bioelectric potentials;biomembrane transport;calcium;cardiology;physiological models;