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Harold P Erickson, Professor of Cell Biology and Biomedical Engineering  


Harold P Erickson
Contact Info:
Office Location:  367 Nanaline H Duke
Email Address:   send me a message
Web Page: http://note.cellbio.duke.edu/Faculty/Research/Erickson.html

Education:

Ph.D., Johns Hopkins University, 1968
Specialties:

Contraception, Biofluid Mechanics
Representative Publications   (More Publications)

  1. T Ohashi, SD Galiacy, G Briscoe, HP Erickson, An experimental study of GFP-based FRET, with application to intrinsically unstructured proteins., Protein science : a publication of the Protein Society, United States, vol. 16 no. 7 (July, 2007), pp. 1429-38  [abs].
  2. HP Erickson, Evolution of the cytoskeleton., BioEssays : news and reviews in molecular, cellular and developmental biology, United States, vol. 29 no. 7 (July, 2007), pp. 668-77  [abs].
  3. S Takahashi, M Leiss, M Moser, T Ohashi, T Kitao, D Heckmann, A Pfeifer, H Kessler, J Takagi, HP Erickson, R Fässler, The RGD motif in fibronectin is essential for development but dispensable for fibril assembly., The Journal of cell biology, United States, vol. 178 no. 1 (July, 2007), pp. 167-78  [abs].
  4. -PDFs of most of my recent papers are available at
    http://www.cellbio.duke.edu/Faculty/Research/Erickson.html     .
  5. M Osawa, HP Erickson, FtsZ from divergent foreign bacteria can function for cell division in Escherichia coli., Journal of bacteriology, United States, vol. 188 no. 20 (October, 2006), pp. 7132-40  [abs].
  6. GE White, HP Erickson, Sequence divergence of coiled coils--structural rods, myosin filament packing, and the extraordinary conservation of cohesins., Journal of structural biology, United States, vol. 154 no. 2 (May, 2006), pp. 111-21  [abs].
  7. M Osawa, HP Erickson, Probing the domain structure of FtsZ by random truncation and insertion of GFP., Microbiology (Reading, England), England, vol. 151 no. Pt 12 (December, 2005), pp. 4033-43  [abs].
  8. T Ohashi, HP Erickson, Domain unfolding plays a role in superfibronectin formation., The Journal of biological chemistry, United States, vol. 280 no. 47 (November, 2005), pp. 39143-51  [abs].
  9. Y Chen, HP Erickson, Rapid in vitro assembly dynamics and subunit turnover of FtsZ demonstrated by fluorescence resonance energy transfer., The Journal of biological chemistry, United States, vol. 280 no. 23 (June, 2005), pp. 22549-54  [abs].
  10. CA Sontag, JT Staley, HP Erickson, In vitro assembly and GTP hydrolysis by bacterial tubulins BtubA and BtubB., The Journal of cell biology, United States, vol. 169 no. 2 (April, 2005), pp. 233-8  [abs].
  11. SD Redick, J Stricker, G Briscoe, HP Erickson, Mutants of FtsZ targeting the protofilament interface: effects on cell division and GTPase activity., Journal of bacteriology, United States, vol. 187 no. 8 (April, 2005), pp. 2727-36  [abs].
  12. Y Chen, K Bjornson, SD Redick, HP Erickson, A rapid fluorescence assay for FtsZ assembly indicates cooperative assembly with a dimer nucleus., Biophysical journal, United States, vol. 88 no. 1 (January, 2005), pp. 505-14  [abs].
  13. DE Anderson, FJ Gueiros-Filho, HP Erickson, Assembly dynamics of FtsZ rings in Bacillus subtilis and Escherichia coli and effects of FtsZ-regulating proteins., Journal of bacteriology, United States, vol. 186 no. 17 (September, 2004), pp. 5775-81  [abs].
  14. T Ohashi, HP Erickson, The disulfide bonding pattern in ficolin multimers., The Journal of biological chemistry, United States, vol. 279 no. 8 (February, 2004), pp. 6534-9  [abs].
  15. J Stricker, HP Erickson, In vivo characterization of Escherichia coli ftsZ mutants: effects on Z-ring structure and function., Journal of bacteriology, United States, vol. 185 no. 16 (August, 2003), pp. 4796-805  [abs].
  16. T Ohashi, DP Kiehart, HP Erickson, Dual labeling of the fibronectin matrix and actin cytoskeleton with green fluorescent protein variants., Journal of cell science, England, vol. 115 no. Pt 6 (March, 2002), pp. 1221-9  [abs].
  17. J Stricker, P Maddox, ED Salmon, HP Erickson, Rapid assembly dynamics of the Escherichia coli FtsZ-ring demonstrated by fluorescence recovery after photobleaching., Proceedings of the National Academy of Sciences of the United States of America, United States, vol. 99 no. 5 (March, 2002), pp. 3171-5  [abs].
  18. HP Erickson, Stretching fibronectin., Journal of muscle research and cell motility, Netherlands, vol. 23 no. 5-6 (2002), pp. 575-80  [abs].
  19. HP Erickson, Gamma-tubulin nucleation: template or protofilament?, Nature cell biology, ENGLAND, vol. 2 no. 6 (June, 2000), pp. E93-6  [abs].
  20. SD Redick, DL Settles, G Briscoe, HP Erickson, Defining fibronectin's cell adhesion synergy site by site-directed mutagenesis., The Journal of cell biology, UNITED STATES, vol. 149 no. 2 (April, 2000), pp. 521-7  [abs].
  21. T Ohashi, DP Kiehart, HP Erickson, Dynamics and elasticity of the fibronectin matrix in living cell culture visualized by fibronectin-green fluorescent protein., Proceedings of the National Academy of Sciences of the United States of America, UNITED STATES, vol. 96 no. 5 (March, 1999), pp. 2153-8  [abs].
  22. T Ohashi, HP Erickson, Oligomeric structure and tissue distribution of ficolins from mouse, pig and human., Archives of biochemistry and biophysics, UNITED STATES, vol. 360 no. 2 (December, 1998), pp. 223-32  [abs].
  23. TE Melby, CN Ciampaglio, G Briscoe, HP Erickson, The symmetrical structure of structural maintenance of chromosomes (SMC) and MukB proteins: long, antiparallel coiled coils, folded at a flexible hinge., The Journal of cell biology, UNITED STATES, vol. 142 no. 6 (September, 1998), pp. 1595-604  [abs].
  24. ET O'Brien, ED Salmon, HP Erickson, How calcium causes microtubule depolymerization., Cell motility and the cytoskeleton, UNITED STATES, vol. 36 no. 2 (1997), pp. 125-35  [abs].
  25. DJ Leahy, I Aukhil, HP Erickson, 2.0 A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region., Cell, UNITED STATES, vol. 84 no. 1 (January, 1996), pp. 155-64  [abs].
  26. HP Erickson, DW Taylor, KA Taylor, D Bramhill, Bacterial cell division protein FtsZ assembles into protofilament sheets and minirings, structural homologs of tubulin polymers., Proceedings of the National Academy of Sciences of the United States of America, UNITED STATES, vol. 93 no. 1 (January, 1996), pp. 519-23  [abs].
  27. HP Erickson, Reversible unfolding of fibronectin type III and immunoglobulin domains provides the structural basis for stretch and elasticity of titin and fibronectin., Proceedings of the National Academy of Sciences of the United States of America, UNITED STATES, vol. 91 no. 21 (October, 1994), pp. 10114-8  [abs].
  28. HP Erickson, Gene knockouts of c-src, transforming growth factor beta 1, and tenascin suggest superfluous, nonfunctional expression of proteins., The Journal of cell biology, UNITED STATES, vol. 120 no. 5 (March, 1993), pp. 1079-81 .
  29. DJ Leahy, WA Hendrickson, I Aukhil, HP Erickson, Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein., Science (New York, N.Y.), UNITED STATES, vol. 258 no. 5084 (November, 1992), pp. 987-91  [abs].
  30. SH Northrup, HP Erickson, Kinetics of protein-protein association explained by Brownian dynamics computer simulation., Proceedings of the National Academy of Sciences of the United States of America, UNITED STATES, vol. 89 no. 8 (April, 1992), pp. 3338-42  [abs].
  31. HP Erickson, Co-operativity in protein-protein association. The structure and stability of the actin filament., Journal of molecular biology, ENGLAND, vol. 206 no. 3 (April, 1989), pp. 465-74  [abs].
  32. RA Walker, ET O'Brien, NK Pryer, MF Soboeiro, WA Voter, HP Erickson, ED Salmon, Dynamic instability of individual microtubules analyzed by video light microscopy: rate constants and transition frequencies., The Journal of cell biology, UNITED STATES, vol. 107 no. 4 (October, 1988), pp. 1437-48  [abs].
  33. WA Voter, HP Erickson, The kinetics of microtubule assembly. Evidence for a two-stage nucleation mechanism., The Journal of biological chemistry, UNITED STATES, vol. 259 no. 16 (August, 1984), pp. 10430-8  [abs].
  34. WE Fowler, HP Erickson, Trinodular structure of fibrinogen. Confirmation by both shadowing and negative stain electron microscopy., Journal of molecular biology, UNITED STATES, vol. 134 no. 2 (October, 1979), pp. 241-9 .
  35. HP Erickson, Microtubule surface lattice and subunit structure and observations on reassembly., The Journal of cell biology, UNITED STATES, vol. 60 no. 1 (January, 1974), pp. 153-67 .
  36. HP Erickson, JL Inglesias, A six-armed oligomer isolated from cell surface fibronectin preparations., Nature, ENGLAND, vol. 311 no. 5983 , pp. 267-9  [abs].
Biomedical Engineering Department
Pratt School of Engineering | Duke University
Room 136 Hudson Hall • Box 90281 • Durham, NC 27708-0281
Phone: (919) 660-5131 • Fax: (919) 684-4488