Publications [#63184] of Mark W. Dewhirst

Papers Published

1. Dewhirst, M. W. and Gross, J. F. and Sim, D. A., EFFECTS OF HEATING RATE ON NORMAL AND TUMOR MICROCIRCULATORY FUNCTION., American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD, vol. 61 (1986), pp. 75 - 80, Anaheim, CA, USA
   (last updated on 2007/04/14)

   Abstract:
   Single vessel responses to hyperthermia were studied in tumor and healing subcutaneous tissues using a transparent access window chamber. Arterioles and venules, with diameters ranging from 15 to 150 mu were studied in both tissues. Rates of heating less than equivalent to 0. 68 degree C/min resulted in persistent normal arteriolar flow up to 45 degree C, but resulted in vascular stasis at a mean of 42. 5 degree C in tumor vessels. Mean times for stoppage of arteriolar flow were 45. 2 plus or minus 13. 1 and 25. 5 plus or minus 2. 6 min for each tissue, respectively, for a 0. 1 degree C/min heating rate.

   Keywords:
   BIOMEDICAL ENGINEERING - Patient Treatment;