Publications [#64522] of Bruce M. Klitzman

Papers Published

1. Sharkawy, A.A. and Klitzman, B. and Truskey, G.A. and Reichert, W.M., Diffusion properties of capsular tissue, Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium, vol. 2 (1996), pp. 132 -, Toronto, Can
   (last updated on 2007/04/15)

   Abstract:
   The effect of capsule formation around a subcutaneous implant is discussed. Polyvinyl alcohol sponge and stainless steel wire mesh materials were implanted. The results show that the diffusion coefficients of fluorescein through capsular tissue are approximately 25% lower than those through the subcutaneous tissue. The tissue which encapsulates subcutaneously implanted sensors will retard the diffusion of low molecular weight analytes diffusing from the microvasculature and the extent of diffusion depends on the thickness and vascularity of the capsule.

   Keywords:
   Tissue;Diffusion in solids;Biocompatibility;Morphology;Computer simulation;Mathematical models;Transport properties;Polyvinyl alcohols;Stainless steel;Physiological models;Finite difference method;