- Dwyer, C. and Vicci, L. and Poulton, J. and Erie, D. and Superfine, R. and Washburn, S. and Taylor, R.M., II, The design of DNA self-assembled computing circuitry,
IEEE Trans. Very Large Scale Integr. (VLSI) Syst. (USA), vol. 12 no. 11
pp. 1214 - 20 [TVLSI.2004.836322] .
(last updated on 2007/04/17)
We present a design methodology for a nanoscale self-assembling fabrication process that uses the specificity of DNA hybridization to guide the formation of electrical circuitry. Custom design software allows us to specify the function of a structure in a way similar to that used by VLSI circuit designers. In an analogous manner to generating masks for a photolithographic process, our software generates an assembly procedure including DNA sequence allocation. We have found that the number of unique DNA sequences needed to assemble a structure scales with its surface area. Using a simple face-serial assembly order we can specify an unambiguous assembly sequence for a structure of any size with only 15 unique DNA sequences
computer architecture;DNA;logic gates;masks;nanoelectronics;parallel processing;photolithography;self-assembly;