Papers Published

1. Zhang, Tianhao and Chakrabarty, Krishnendu and Fair, Richard B., Behavioral modeling and performance evaluation of microelectrofluidics- based PCR systems using systemC, IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems, vol. 23 no. 6 (2004), pp. 843 - 858 [TCAD.2004.828115] .
   (last updated on 2007/04/17)

   Abstract:
   Composite microsystems that incorporate microelectromechanical and microelectrofluidic devices are emerging as the next generation of system-on-a-chip (SOC). We present a performance comparison between two types of microelectrofluidic systems (MEFS): continuous-flow systems and droplet-based systems. The comparison is based on a specific microelectrofluidic application - a polymerase chain reaction (PCR) system. The behavioral modeling, simulation, and performance evaluation are based on a SystemC design environment. The performance comparison includes the system throughput, system-correction capacity, system-processing capacity, and system-design complexity. By using our system-performance evaluation environment, we demonstrated that the droplet-based MEFS provides higher performance, as well as lower design and integration complexity.

   Keywords:
   Channel flow;Microprocessor chips;Systems analysis;Microstructure;DNA;Enzyme kinetics;Purification;Computer simulation;Optimization;