| Publications [#260831] of Ashutosh Chilkoti
search scholar.google.com.Papers Published
- Nettles, DL; Chilkoti, A; Setton, LA, Applications of elastin-like polypeptides in tissue engineering.,
Advanced drug delivery reviews, vol. 62 no. 15
(December, 2010),
pp. 1479-1485 [20385185], [doi]
(last updated on 2024/04/19)
Abstract: Elastin-like polypeptides (ELPs) have found utility in tissue engineering applications, not only because they are biocompatible, biodegradable, and non-immunogenic, but also because their amino acid sequence and molecular weight can be precisely controlled at the genetic or synthetic level, affording exquisite control over final protein functionality. This review presents a basic overview of ELP properties and modifications that are relevant to tissue engineering, as well as a discussion of the application of ELPs to cartilage, intervertebral disc, vascular graft, liver, ocular, and cell sheet engineering.
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