Publications [#260912] of Ashutosh Chilkoti

Papers Published

1. Chilkoti, A; Christensen, T; MacKay, JA, Stimulus responsive elastin biopolymers: Applications in medicine and biotechnology., Current opinion in chemical biology, vol. 10 no. 6 (December, 2006), pp. 652-657, ISSN 1367-5931 [17055770], [doi]
   (last updated on 2024/04/25)

   Abstract:
   Elastin-like polypeptides (ELPs) are artificial polypeptides, derived from Val-Pro-Gly-Xaa-Gly (VPGXG) pentapeptide repeats found in human tropoelastin, that reversibly coacervate above a critical temperature. Genetically encodable ELPs are monodisperse, stimuli responsive, and biocompatible, properties that make them attractive for drug delivery and tissue engineering. The potential of ELPs to self-assemble into nanostructures in response to environmental triggers is another interesting feature of these polypeptides that promises to lead to a host of new applications.