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Pratt School of Engineering
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Publications [#260920] of Ashutosh Chilkoti

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Papers Published

  1. Xu, F; Joon, HM; Trabbic-Carlson, K; Chilkoti, A; Knoll, W, Surface plasmon optical study of the interfacial phase transition of elastinlike polypeptide grafted on gold., Biointerphases, vol. 3 no. 3 (September, 2008), pp. 66-74, ISSN 1559-4106 [20408702], [doi]
    (last updated on 2024/03/29)

    Abstract:
    The conformational changes in elastinlike polypeptides (ELPs) grafted to a solid/solution interface via different architectures were studied using surface plasmon resonance spectroscopy and surface plasmon field-enhanced fluorescence spectroscopy (SPFS). SPFS provides a simple and convenient optical method to study the influence of the grafting method and the graft density on the conformational changes in ELPs at the solid-solution interface as a function of environmental variables. A typical response of the ELP, consistent with its stimuli responsiveness, was a gradual collapse upon increasing the ionic strength; this effect was inversely correlated with the surface graft density of the ELP.


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