Publications [#63260] of Mark W. Dewhirst

Papers Published

1. Waterman, F.M. and Dewhirst, M.W. and Fessenden, P. and Samulski, T.V. and Stauffer, P. and Emami, B. and Corry, P. and Prionas, S.D. and Sapozink, M. and Herman, T. and Kapp, D.S. and Myerson, R.J. and Ryan, T. and Sapareto, S.A. and Shrivastava, P., RTOG quality assurance guidelines for clinical trials using hyperthermia administered by ultrasound, Int. J. Radiat. Oncol. Biol. Phys. (UK), vol. 20 no. 5 (1991), pp. 1099 - 107
   (last updated on 2007/04/14)

   Abstract:
   Clinical quality assurance guidelines are established for RTOG hyperthermia protocols in which unfocused planar ultrasound may be used to administer hyperthermia. Measurement of temperature at a few fixed points is no longer considered to be adequate. Thermal mapping is required to obtain profiles of the temperature across the tumor dimensions, including margins of normal tissue. The thermometry strategies established for microwaves are to be adhered to with oblique insertion of the probes recommended. Two types of errors arise which are generally not present with microwaves. A measurement error, commonly referred to as a temperature artifact, arises because of absorption and/or viscous heating of the probe. Another error arises when thermocouples are used due to the conduction of heat along the wire leads, especially the copper wire. Several thermometry systems are evaluated with regard to the expected artifact and conduction errors

   Keywords:
   biomedical ultrasonics;biothermics;measurement errors;quality control;radiation therapy;