Publications [#132795] of G. Allan Johnson
- GA Johnson, GP Cofer, SL Gewalt, LW Hedlund, Morphologic phenotyping with MR microscopy: the visible mouse.,
Radiology, United States, vol. 222 no. 3
pp. 789-93, ISSN 0033-8419
(last updated on 2005/08/03)
A method for rapid morphologic phenotyping is demonstrated by using magnetic resonance microscopy. Whole fixed C57BL/6J mice were imaged at 110-microm isotropic resolution; limited volumes of the intact specimen, at 50-microm isotropic resolution; and isolated organs, at 25-microm isotropic resolution. The three-dimensional imaging technique was applied to uricase knockout mice to demonstrate the method for the evaluation of morphologic phenotype.
Animals • Contrast Media • Gadolinium DTPA • Imaging, Three-Dimensional* • Magnetic Resonance Imaging • Male • Mice • Mice, Inbred C57BL • Mice, Knockout • Microscopy • Phenotype • Urate Oxidase • administration & dosage • anatomy & histology* • diagnostic use • genetics • methods*