Research Interests for Glenn S. Edwards

Glenn Edwards investigates biological systems using a range of experimental techniques and theoretical methods from physics. His interests include Investigations of energy transduction where laser energy transforms into vibrational energy of biological molecules which then transforms into heat and pressure pulses that selectively drive tissue-scale dynamics. This line of research has led to human surgical applications of Free-Electron Lasers and spin-off laser technology. Another interest includes investigations of how biology harnesses physical mechanisms in biomechanical processes. This line of research investigates tissue dynamics and pattern formation during early development in Drosophila embryos.

Keywords:

Actins, Adolescent, Aged, Animal Structures, Animals, Animals, Genetically Modified, Apoptosis, Biology, Brain, Brain Chemistry, Cadherins, Cattle, Cell Adhesion, Cell Movement, Cell Polarity, Cell Shape, Computer Simulation, Corneal Stroma, Cytochromes c, Drosophila, Drosophila melanogaster, Drosophila Proteins, Electron Spin Resonance Spectroscopy, Electrons, Embryo, Nonmammalian, Embryonic Development, Epidermis, Epithelial Cells, Epithelium, Equipment Design, Female, Gene Expression Regulation, Developmental, Genes, Insect, Green Fluorescent Proteins, Humans, Image Processing, Computer-Assisted, Infrared Rays, Integrin alpha Chains, Integrins, Laser Therapy, Lasers, Light, Lipofuscin, Mathematics, Mechanotransduction, Cellular, Melanins, Melanosomes, Microscopy, Atomic Force, Microscopy, Confocal, Microscopy, Electron, Microscopy, Electron, Scanning, Microscopy, Fluorescence, Microsurgery, Middle Aged, Models, Biological, Morphogenesis, Mutation, Optics and Photonics, Oscillometry, Oxidation-Reduction, Oxygen, Photochemical Processes, Photochemistry, Pigment Epithelium of Eye, Proteins, Pseudopodia, Rats, Rats, Sprague-Dawley, Recombinant Fusion Proteins, Retina, Scattering, Radiation, Sepia, Serous Membrane, Skin Neoplasms, Sodium Chloride, Spectrophotometry, Spectrophotometry, Ultraviolet, Spectrum Analysis, Spectrum Analysis, Raman, Stress, Mechanical, Substantia Nigra, Surface Properties, Surgical Procedures, Operative, Swine, Time Factors, Ultraviolet Rays, Up-Regulation

Recent Publications

1. with Shape changes of cytoskeletal actin filaments, Biophysical Journal (Submitted, 2019) [abs]
2. Aristotelous, AC; Crawford, JM; Edwards, GS; Kiehart, DP; Venakides, S, Mathematical models of dorsal closure., Progress in biophysics and molecular biology, vol. 137 (September, 2018), pp. 111-131 [doi] [abs]
3. Lo, W-C; Madrak, C; Kiehart, DP; Edwards, GS, Unified biophysical mechanism for cell-shape oscillations and cell ingression., Physical review. E, vol. 97 no. 6-1 (June, 2018), pp. 062414 [doi] [abs]
4. Kiehart, DP; Crawford, JM; Aristotelous, A; Venakides, S; Edwards, GS, Cell Sheet Morphogenesis: Dorsal Closure in Drosophila melanogaster as a Model System., Annual review of cell and developmental biology, vol. 33 (October, 2017), pp. 169-202 [doi] [abs]
5. Lu, H; Sokolow, A; Kiehart, DP; Edwards, GS, Quantifying dorsal closure in three dimensions., Molecular biology of the cell, vol. 27 no. 25 (December, 2016), pp. 3948-3955 [doi] [abs]