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Publications [#113090] of Harold P. Erickson

Papers Published

  1. T Ohashi, CA Hale, PA de Boer, HP Erickson, Structural evidence that the P/Q domain of ZipA is an unstructured, flexible tether between the membrane and the C-terminal FtsZ-binding domain., Journal of bacteriology, United States, vol. 184 no. 15 (August, 2002), pp. 4313-5, ISSN 0021-9193
    (last updated on 2009/02/12)

    Abstract:
    The cell division protein ZipA has an N-terminal transmembrane domain and a C-terminal globular domain that binds FtsZ. Between them are a charged domain and a P/Q domain rich in proline and glutamine that has been proposed to be an unfolded polypeptide. Here we provide evidence obtained by electron microscopy that the P/Q domain is a flexible tether ranging in length from 8 to 20 nm and invisible in rotary shadowing electron microscopy. We estimated a persistence length of 0.66 nm, which is similar to the persistence lengths of other unfolded and unstructured polypeptides.

    Keywords:
    Bacterial Proteins • Carrier Proteins • Cell Cycle Proteins • Cell Division • Cytoskeletal Proteins* • Escherichia coli • Escherichia coli Proteins* • Glutamine • Green Fluorescent Proteins • Luminescent Proteins • Microscopy, Electron • Models, Molecular • Proline • Protein Binding • Protein Conformation • chemistry • chemistry* • ultrastructure


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