| Publications [#113157] of Harold P. Erickson
Papers Published
- HP Erickson, The FtsZ protofilament and attachment of ZipA--structural constraints on the FtsZ power stroke.,
Current opinion in cell biology, United States, vol. 13 no. 1
(February, 2001),
pp. 55-60, ISSN 0955-0674
(last updated on 2009/02/12)
Abstract: Bacterial cell division protein FtsZ forms protofilaments in vitro that can shift from a straight to a curved conformation. The inside of the curved protofilaments, which corresponds to the carboxyl terminus, should face the center of the cell as curvature increases during constriction of the Z-ring. ZipA, a membrane-tethered division protein, binds to a highly conserved short peptide on the carboxyl terminus of FtsZ. A model is proposed here for how membrane-bound ZipA can reach around the FtsZ protofilament to bind the carboxy-terminal peptide, which faces away from the membrane.
Keywords: Amino Acid Sequence • Bacterial Proteins • Carrier Proteins • Cell Cycle Proteins • Cell Division • Cytoskeletal Proteins* • Escherichia coli Proteins* • Models, Molecular • Molecular Sequence Data • Protein Conformation • Structure-Activity Relationship • chemistry* • physiology • physiology*
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