| Publications [#113179] of Harold P. Erickson
Papers Published
- FA Lai, HP Erickson, E Rousseau, QY Liu, G Meissner, Purification and reconstitution of the calcium release channel from skeletal muscle.,
Nature, ENGLAND, vol. 331 no. 6154
(January, 1988),
pp. 315-9, ISSN 0028-0836
(last updated on 2009/02/12)
Abstract: The calcium release channel from rabbit muscle sarcoplasmic reticulum (SR) has been purified and reconstituted as a functional unit in lipid bilayers. Electron microscopy reveals the four-leaf clover structure previously described for the 'feet' that span the transverse tubule (T)-SR junction. Ca2+ release from the SR induced by T-system depolarization during excitation-contraction coupling in muscle may thus be effected through a direct association of the T-system with SR Ca2+-release channels.
Keywords: Animals • Calcium • Ion Channels • Liposomes • Membrane Potentials • Rabbits • Receptors, Cholinergic • Ryanodine Receptor Calcium Release Channel • Sarcoplasmic Reticulum • analysis* • isolation & purification* • metabolism • ultrastructure
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