Lingchong You, Professor of Biomedical Engineering

Dr. You's research interest focus on computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.

Office Location:	1381 CIEMAS
Office Phone:	(919) 660-8408
Email Address:
Web Page:	http://www.genome.duke.edu/labs/YouLab/

Teaching (Spring 2024):

BME 590.09, SPECIAL TOPICS Synopsis
Hudson 201, MW 01:25 PM-02:40 PM
BME 713S.01, QBIO SEMINAR SERIES Synopsis
021, F 03:00 PM-04:00 PM

Teaching (Fall 2024):

BME 574.01, GENE CIRCUITS Synopsis
Hudson 224, MW 01:25 PM-02:40 PM
(also cross-listed as CBB 574.01)

Education:

PhD	University of Wisconsin	2002
MS	USTC-China	1997
BE	Chengdu University	1994

Specialties:: Genomics
Computational Biology
Nonlinear Dynamics

Research Interests:: Dr. You's research interest focus on computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.

Recent Publications

Y. Tanouchi and D. Tu and J. Kim and L. You, Noise Reduction by Diffusional Dissipation in a Minimal Quorum Sensing Motif, Plos Computational Biology, vol. 4 no. 8 (August, 2008), ISSN 1553-734X [abs]
L. You and J. Yin, Evolutionary design on a budget: robustness and optimality of bacteriophage T7, Iee Proceedings Systems Biology, vol. 153 no. 2 (March, 2006), pp. 46 -- 52, ISSN 1741-2471 [abs]
R. Srivastava and L. You and J. Summers and J. Yin, Stochastic vs. deterministic modeling of intracellular viral kinetics, Journal Of Theoretical Biology, vol. 218 no. 3 (October, 2002), pp. 309 -- 321, ISSN 0022-5193 [abs]
D. Endy and L. You and I. J. Molineux and J. Yin, Prediction, design, and characterization of alternate genetic element orders for bacteriophage T7., Abstracts Of Papers Of The American Chemical Society, vol. 217 (March, 1999), pp. U205 -- U205, ISSN 0065-7727
L. You and F. H. Arnold, Directed evolution of subtilisin E in Bacillus subtilis to enhance total activity in aqueous dimethylformamide, Protein Engineering, vol. 9 no. 1 (January, 1996), pp. 77 -- 83, ISSN 0269-2139 [abs]