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Pratt School of Engineering
Duke University

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Publications of Nimmi Ramanujam    :chronological  alphabetical  combined  bibtex listing:

Books

  1. Handbook of Biomedical Optics, edited by Boas DA, Pitris C, Ramanujam N. (2011), CRC Press

Book Chapters

  1. Vishwanath K, Palmer GM, Brown JQ, and Ramanujam N, Non-invasive and quantitative sensing of tumor physiology and function via steady-state diffuse optical spectroscopy, in Biosensors and Biodetection Technologies for Cancer Detection, Diagnostics and Research (2012)
  2. Ramanujam N, Vishwanath K, Palmer GM, Brown JQ, Non-invasive and quantitative sensing of tumor physiology and function via steady-state diffuse optical spectroscopy, in Biosensors and biodetection technologies for cancer detection, diagnostics and research, edited by Rasooly, A. and Herold, K. (2011), CRC Press
  3. Brown JQ, Vishwanath K, Chang TVC, Ramanujam N, Clinical Applications of UV-VIS Optical Spectroscopy in Cervix, Head and Neck, and Breast Cancer, in In Vivo Clinical Imaging and Diagnosis, edited by J. Tunnell (2011), pp. 239-285
  4. Brown JQ, Bydlon TM, Richards LM, Yu B, Kennedy SA, Wilke LG, Geradts J, Junker M, Gallagher J, Ramanujam N, Optical assessment of tumor resection margins in the breast, in IEEE Journal of Selected Topics on Quantum Electronics, vol. 20 (submitted, August 2009.), pp. 119-131
  5. Skala MC and Ramanujam N., Multiphoton Redox Ratio Imaging for Metabolic Monitoring in vivo, in Advanced Protocols in Oxidative Stress, edited by Ed. Don Armstrong, vol. 594 (2010), pp. 155-162
  6. Brown JQ, Vishwanath K, Palmer GM, Ramanujam N., Advances in quantitative UV-visible spectroscopy for clinical and pre-clinical application in cancer, in Current Opinion in Biotechnology, vol. 20 (2009), pp. 119-131
  7. Palmer GM, Ramanujam N, Diagnosis of breast cancer using optical spectroscopy, in Medical Laser Applications, vol. 18 no. 3 (2003), pp. 233-48
  8. Gill EM, Palmer GM, Ramanujam N, Steady-state fluorescence imaging of Neoplasia, in Methods in Enzymology, vol. 361 (2003), pp. 452-481, Academic Press
  9. Ramanujam N, Fluorescence spectroscopy of neoplastic and non-neoplastic tissues, in Neoplasia (2000)
  10. Ramanujam N, Fluorescence Spectroscopy In Vivo, in Encyclopedia of Analytical Chemistry (2000), pp. 20-56, ohn Wiley & Sons
  11. Ramanujam N, Boas DA, Li Y, Laser spectroscopy and imaging for characterization of tissue, In: Lasers in Surface Engineering, in ASM International Materials Park OH, 523-594 (1998)
  12. Ramanujam N, Mitchell MF, Mahadevan A, Thomsen S, Silva E, Richards-Kortum RR, Fluorescence spectroscopy: a diagnostic tool for Cervical Intraepithelial Neoplasia, In: Female Genital Tract, in Stoler MH (Eds.) Mosby-Year Book (1995)

Papers Published

  1. Lo JY, Brown JQ, Dhar S, Yu B, Jokerst NM, Ramanujam N, Wavelength optimization for quantitative spectral imaging of breast tumor margins, PLoS ONE (April, 2013)
  2. Zhong J, Rajaram N, Brizel DM, Frees AE, Ramanujam N, Batinic-Haberle I, Dewhirst MW, Radiation induces aerobic glycolysis through reactive oxygen species, Radiotherapy and Oncology (March, 2013)
  3. Fu H, Mueller J, Javid M, Mito J, Kirsch D, Ramanujam N, Brown Q, Optimization of a Widefield Structured Illumination Microscope for Non-Destructive Assessment and Quantification of Nuclear Features in Tumor Margins of a Primary Mouse Model of Sarcoma, PLoS one (2013)
  4. Mueller J, Harmany Z, Mito K, Kennedy S, Kim Y, Dodd L, Geradts J, Kirsch D, Willett R, Brown Q, Ramanujam N, Quantitative segmentation of fluorescence microscopy images of heterogeneous tissue: Application to the detection of residual disease in tumor margins (2013)
  5. Brown JQ, Ramanujam N, Leveraging tissue composition and micro-morpholoy or breast tumor margin assessment via quantitative diffuse optical spectral imaging, PLoS ONE (2013)
  6. Liu C, Rajaram N, Vishwanath K, Jiang T, Palmer G, and N. Ramanujam, Experimental Validation of an Inverse Fluorescence Monte Carlo Model to Extract Concentrations of Metabolically Relevant Fluorophores from Turbid Phantoms and a Murine Tumor Model, Journal of Biomedical Optics (2012)
  7. Dhar S, Lo JY, Palmer GM, Brooke MA, Nichols BS, Yu B, Ramanujam N, Jokerst NM, A diffuse reflectance spectral imaging system for tumor margin assessment using custom annular photodiode arrays, Biomedical Optics Express, vol. 3 no. 12 (2012), pp. 3211-3222
  8. Bydlon TM, Barry WT, Kennedy SA, Brown JQ, Gallagher JE, Ramanujam N, Advancing Optical Imaging for Breast Margin Assessment: An Analysis of Excisional Time, Cautery, and Patent Blue Dye on Underlying Sources of Contrast, PLoS ONE (2012)
  9. Yu B, Shah A, Wang B, Rajaram N, Wang Q, Ramanujam N, Palmer GM, Dewhirst MW, Measuring tumor cycling hypoxia and angiogenesis using a side-firing fiber optic probe, Journal of Biophotonics (2012)
  10. Vishwanath K, Chang K, Klein D, Chang V, Deng YF, Phelps JE, Ramanujam N, Portable Fiber Based Diffuse Reflectance Spectroscopy Systems for Estimating Tissue Optical Parameters, Applied Spectroscopy, vol. 65 no. 2 (2011), pp. 011010-12
  11. Beumer, W.H., Vishwanath, K., Puscas, L., Afshari, H., Ramanujam, N. and Lee, W, Detection of Squamous Cell Carcinoma and corresponding biomarkers using optical spectroscopy, Otolaryngology Head and Neck Surgery, vol. 144 no. 3 (2011), pp. 390-394
  12. Lo JY, Yu B, Kuech TF, Ramanujam N, A compact, cost-effective diffuse reflectance spectroscopic imaging system for quantitative tissue absorption and scattering, Proc. of SPIE, Vol. 7890, San Francisco, CA. (2011)
  13. Yu B, Fu HL and Ramanujam N, Instrument-Independent Diffuse Reflectance Spectroscopy, JBO, vol. 16 no. 1 (2011), pp. 011010
  14. Chang VTC, Merisier D, Yu B, Walmer DK, and Ramanujam N, Towards a field-compatible optical Spectroscopic device for cervical cancer screening in resource-limited settings: effects of calibration and pressure, Optics Express, in press (2011)
  15. Millon SR, Ostrander JH, Brown JQ, Rajeha AM, Seewaldt VL, Ramanujam N, Uptake of 2-NBDG as a method to monitor therapy response in breast cancer cell lines, Breast Cancer Research and Treatment, vol. 126 no. 1 (2011), pp. 55-62
  16. J.H. Ostrander, C.M. McMahon, S. Lem, S.R. Millon, V.L. Seewaldt, N. Ramanujam, The Optical Redox Ratio Differentiates Breast Cancer Cell Lines Based on Receptor Status, Cancer Research, vol. 70 no. 11 (2010), pp. 4759-4766
  17. Bydlon TM, Kennedy SA, Richards LM, Brown JQ, Yu B, Junker MS, Gallagher J, Geradts J, Wilke LG, Ramanujam N, Performance metrics of an optical spectral imaging system for intra-operative assessment of breast tumor margins, Optics Express, vol. 19 no. 8 (2010), pp. 8058-8076
  18. Chang VTC, Bean SM, Cartwright PS, Ramanujam N, CD34 Immunohistochemical Validation of Increased Hemoglobin through Optical Spectroscopy in the Precancerous Cervix, JBO, vol. 15 no. 5 (2010)
  19. Fu HL, Yu B, Lo JY, Palmer GM, Kuech TF, Ramanujam N, A Cost-Effective, Portable, and Quantitative Spectral Imaging System for Application to Biological Tissues, Optics Express, vol. 18 no. 12 (2010), pp. 12630-12645
  20. Gill EM, Straseki JA, Rasmussen CA, Liliensiek SJ, Eliceiri KW, Ramanujam N, Visualization of morphological and molecular features associated with chronic ischemia in bioengineered human skin, Microsc Microanal, vol. 16 no. 2 (2010), pp. 117-131
  21. 75. Phelps JE, Vishwanath K, Chang VTC, Ramanujam N, Rapid ratiometric determination of hemoglobin concentration using UV-VIS diffuse reflectance at isosbestic wavelengths, Optics Express, vol. 18 no. 18 (2010), pp. 18779-18792
  22. Brown JQ, Bydlon TM, Richards LM, Yu B, Kennedy SA, Geradts J, Wilke LG, Junker M, Gallagher J, Barry W, Ramanujam N, Optical assessment of tumor resection margins in the breast, IEEE Journal of Selected Topics in Quantum Electronics, vol. 12 no. 3 (2010), pp. 530-544
  23. Kennedy SA, Geradts G, Bydlon T, Brown JQ, Gallagher J, Junker M, Barry W, Ramanujam N, Wilke L, Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast, Breast Cancer Research, vol. 12 no. 6 (2010), pp. R91
  24. Millon SR, Ostrander JH, Yazdanfar S, Brown JQ, Raheja AM, Ramanujam N., Preferential accumulation of 5-aminolevulinic acid-induced protoporphyrin IX in breast cancer: A comprehensive study on six breast cell lines with varying phenotypes, Journal of Biomedical Optics, vol. 15 no. 1 (2010), pp. 018002
  25. J. E. Bender, A. B. Shang, E. W. Moretti, B. Yu, L. M. Richards, N. Ramanujam, Noninvasive Monitoring of Tissue Hemoglobin Using UV-VIS Diffuse Reflectance Spectroscopy: A Pilot Study, Optics Express, vol. 17 no. 26 (December, 2009), pp. 23396-23409
  26. L. G. Wilke and J. Q. Brown and T. M. Bydlon and S. A. Kennedy and L. M. Richards and M. K. Junker and J. Gallagher and W. T. Barry and J. Geradts and N. Ramanujam, Rapid noninvasive optical imaging of tissue composition in breast tumor margins, American Journal Of Surgery, vol. 198 no. 4 (October, 2009), pp. 566 -- 574, ISSN 0002-9610  [abs]
  27. C. F. Zhu and E. S. Burnside and G. A. Sisney and L. R. Salkowski and J. M. Harter and B. Yu and N. Ramanujam, Fluorescence Spectroscopy: An Adjunct Diagnostic Tool to Image-Guided Core Needle Biopsy of the Breast, Ieee Transactions On Biomedical Engineering, vol. 56 no. 10 (October, 2009), pp. 2518 -- 2528, ISSN 0018-9294  [abs]
  28. K. Vishwanath and D. Klein and K. Chang and T. Schroeder and M. W. Dewhirst and N. Ramanujam, Quantitative optical spectroscopy can identify long-term local tumor control in irradiated murine head and neck xenografts, Journal Of Biomedical Optics, vol. 14 no. 5 (September, 2009), ISSN 1083-3668  [abs]
  29. K. Vishwanath and H. Yuan and W. T. Barry and M. W. Dewhirst and N. Ramanujam, Using Optical Spectroscopy to Longitudinally Monitor Physiological Changes within Solid Tumors, Neoplasia, vol. 11 no. 9 (September, 2009), pp. 889 -- 900, ISSN 1522-8002  [abs]
  30. J. E. Bender and K. Vishwanath and L. K. Moore and J. Q. Brown and V. Chang and G. M. Palmer and N. Ramanujam, A Robust-Monte Carlo Model for the Extraction of Biological Absorption and Scattering In Vivo, Ieee Transactions On Biomedical Engineering, vol. 56 no. 4 (April, 2009), pp. 960 -- 968, ISSN 0018-9294  [abs]
  31. J. Q. Brown and L. G. Wilke and J. Geradts and S. A. Kennedy and G. M. Palmer and N. Ramanujam, Quantitative Optical Spectroscopy: A Robust Tool for Direct Measurement of Breast Cancer Vascular Oxygenation and Total Hemoglobin Content In vivo, Cancer Research, vol. 69 no. 7 (April, 2009), pp. 2919 -- 2926, ISSN 0008-5472  [abs]
  32. G. M. Palmer and R. J. Viola and T. Schroeder and P. S. Yarmolenko and M. W. Dewhirst and N. Ramanujam, Quantitative diffuse reflectance and fluorescence spectroscopy: tool to monitor tumor physiology in vivo, Journal Of Biomedical Optics, vol. 14 no. 2 (March, 2009), ISSN 1083-3668  [abs]
  33. J. Q. Brown and K. Vishwanath and G. M. Palmer and N. Ramanujam, Advances in quantitative UV-visible spectroscopy for clinical and pre-clinical application in cancer, Current Opinion In Biotechnology, vol. 20 no. 1 (February, 2009), pp. 119 -- 131, ISSN 0958-1669  [abs]
  34. J. Y. Lo and B. Yu and H. L. Fu and J. E. Bender and G. M. Palmer and T. F. Kuech and N. Ramanujam, A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes, Optics Express, vol. 17 no. 3 (February, 2009), pp. 1372 -- 1384, ISSN 1094-4087  [abs]
  35. J. Q. Brown and T. M. Bydlon and S. A. Kennedy and L. Richards and M. S. Junker and G. M. Palmer and J. Geradts and L. G. Wilke and N. Ramanujam, Intraoperative optical breast tissue characterization device for tumor margin assessment, Cancer Research, vol. 69 no. 2 (January, 2009), pp. 101S -- 101S, ISSN 0008-5472
  36. Chang VTC, Cartwright PS, Bean SM, Palmer GM, Bentley RC, Ramanujam N., Quantitative physiology of the precancerous cervix in vivo via optical spectroscopy, Neoplasia, vol. 11 no. 4 (2009), pp. 325-332
  37. B. Yu and J. Y. Lo and T. F. Kuech and G. M. Palmer and J. E. Bender and N. Ramanujam, Cost-effective diffuse reflectance spectroscopy device for quantifying tissue absorption and scattering in vivo, Journal Of Biomedical Optics, vol. 13 no. 6 (November, 2008), ISSN 1083-3668  [abs]
  38. M. Lazebnik and C. F. Zhu and G. M. Palmer and J. Harter and S. Sewall and N. Ramanujam and S. C. Hagness, Electromagnetic Spectroscopy of Normal Breast Tissue Specimens Obtained From Reduction Surgeries: Comparison of Optical and Microwave Properties, Ieee Transactions On Biomedical Engineering, vol. 55 no. 10 (October, 2008), pp. 2444 -- 2451, ISSN 0018-9294  [abs]
  39. C. F. Zhu and T. M. Breslin and J. Harter and N. Ramanujam, Model based and empirical spectral analysis for the diagnosis of breast cancer, Optics Express, vol. 16 no. 19 (September, 2008), pp. 14961 -- 14978, ISSN 1094-4087  [abs]
  40. B. Yu and H. Fu and T. Bydlon and J. E. Bender and N. Ramanujam, Diffuse reflectance spectroscopy with a self-calibrating fiber optic probe, Optics Letters, vol. 33 no. 16 (August, 2008), pp. 1783 -- 1785, ISSN 0146-9592  [abs]
  41. C. F. Zhu and G. M. Palmer and T. M. Breslin and J. Harter and N. Ramanujam, Diagnosis of breast cancer using fluorescence and diffuse reflectance spectroscopy: a Monte-Carlo-model-based approach, Journal Of Biomedical Optics, vol. 13 no. 3 (2008), ISSN 1083-3668  [abs]
  42. G. M. Palmer and N. Ramanujam, Monte-Carlo-based model for the extraction of intrinsic fluorescence from turbid media, Journal Of Biomedical Optics, vol. 13 no. 2 (2008), ISSN 1083-3668  [abs]
  43. J. Q. Brown and L. G. Wilke and S. Kennedy and G. M. Palmer and J. Geradts and N. Ramanujam, Intraoperative in vivo reflectance spectroscopy for discrimination of normal, benign, and malignant breast tissues, Breast Cancer Research And Treatment, vol. 106 (December, 2007), pp. S209 -- S210, ISSN 0167-6806
  44. M. C. Skala and K. M. Riching and A. Gendron-fitzpatrick and J. Eickhoff and K. W. Eliceiri and J. G. White and N. Ramanujam, In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia, Proceedings Of The National Academy Of Sciences Of The United States Of America, vol. 104 no. 49 (December, 2007), pp. 19494 -- 19499, ISSN 0027-8424  [abs]
  45. G. M. Palmer and N. Ramanujam, Monte Carlo-based inverse model for calculating tissue optical properties. Part I: Theory and validation on synthetic phantoms (vol 45, pg 1062, 2006), Applied Optics, vol. 46 no. 27 (September, 2007), pp. 6847 -- 6847, ISSN 0003-6935
  46. G. M. Palmer and N. Ramanujam, Use of genetic algorithms to optimize fiber optic probe design for the extraction of tissue optical properties, Ieee Transactions On Biomedical Engineering, vol. 54 no. 8 (August, 2007), pp. 1533 -- 1535, ISSN 0018-9294  [abs]
  47. B. Yu and E. S. Burnside and G. A. Sisney and J. M. Harter and C. Zhu and A. H. Dhalla and N. Ramanujam, Feasibility of near-infrared diffuse optical spectroscopy on patients undergoing image-guided core-needle biopsy, Optics Express, vol. 15 no. 12 (June, 2007), pp. 7335 -- 7350, ISSN 1094-4087  [abs]
  48. M. C. Skala and G. M. Palmer and K. M. Vrotsos and A. Gendron-fitzpatrick and N. Ramanujam, Comparison of a physical model and principal component analysis for the diagnosis of epithelial neoplasias in vivo using diffuse reflectance spectroscopy, Optics Express, vol. 15 no. 12 (June, 2007), pp. 7863 -- 7875, ISSN 1094-4087  [abs]
  49. Q. Liu and N. Ramanujam, Scaling method for fast Monte Carlo simulation of diffuse reflectance spectra from multilayered turbid media, Journal Of The Optical Society Of America A-optics Image Science And Vision, vol. 24 no. 4 (April, 2007), pp. 1011 -- 1025, ISSN 1084-7529  [abs]
  50. Yu B, Burnside Rollins E, Sisney GA, Harter JM, Zhu C, Dhalla AH, and Ramanujam N, Feasibility of Near-Infrared Diffuse Optical Spectroscopy on Patients Undergoing Image-Guided Core-Needle Biopsy, Optics Express, vol. 15 no. 12 (2007), pp. 7335-50
  51. Skala MC, Riching KM, Bird DK, Gendron-Fitzpatrick A, Eickhoff J, Eliceiri KW, Keely PJ, Ramanujam N, In vivo Multiphoton Fluorescence Lifetime Imaging of Protein-bound and Free NADH in Normal and Pre-cancerous Epithelia, Journal of Biomedical Optics, vol. 12 no. 2 (2007), pp. 024014
  52. Skala MC , Riching KM, Gendron-Fitzpatrick A, Eliceiri KW, and Ramanujam N, In vivo multiphoton microscopy of metabolic oxidation-reduction states and fluorescence lifetimes in normal and pre-cancerous epithelia, Proc Nat Acad Sci (2007) (Accepted for publication.)
  53. Skala MC, Palmer GM, Vrotsos KM, Gendron-Fitzpatrick A, Ramanujam N., Comparison of a Monte Carlo based physical model and principal component analysis for the diagnosis of normal and neoplastic epithelial tissues in vivo using diffuse reflectance spectroscopy., Optics Express, vol. 15 no. 12 (2007), pp. 7863-7875
  54. Quan Liu and Ramanujam, N., Scaling method for fast Monte Carlo simulation of diffuse reflectance spectra from multilayered turbid media, J. Opt. Soc. Am. A, Opt. Image Sci. Vis. (USA), vol. 24 no. 4 (2007), pp. 1011 - 25 [JOSAA.24.001011]  [abs]
  55. M. C. Skala and K. M. Riching and D. K. Bird and A. Gendron-fitzpatrick and J. Eickhoff and K. W. Eliceiri and P. J. Keely and N. Ramanujam, In vivo multiphoton fluorescence lifetime imaging of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia, Journal Of Biomedical Optics, vol. 12 no. 2 (2007), ISSN 1083-3668  [abs]
  56. S. R. Millon and K. M. Roldan-perez and K. M. Riching and G. M. Palmer and N. Ramanujam, Effect of optical clearing agents on the in vivo optical properties of squamous epithelial tissue, Lasers In Surgery And Medicine, vol. 38 no. 10 (December, 2006), pp. 920 -- 927, ISSN 0196-8092  [abs]
  57. C. F. Zhu and G. M. Palmer and T. M. Breslin and J. Harter and N. Ramanujam, Diagnosis of breast cancer using diffuse reflectance spectroscopy: Comparison of a Monte Carlo versus partial least squares analysis based feature extraction technique, Lasers In Surgery And Medicine, vol. 38 no. 7 (August, 2006), pp. 714 -- 724, ISSN 0196-8092  [abs]
  58. Q. Liu and N. Ramanujam, Sequential estimation of optical properties of a two-layered epithelial tissue model from depth-resolved ultraviolet-visible diffuse reflectance spectra, Applied Optics, vol. 45 no. 19 (July, 2006), pp. 4776 -- 4790, ISSN 0003-6935  [abs]
  59. E. M. Gill and C. A. Ivarie and K. W. Eliceiri and N. Ramanujam and J. G. White and B. L. Allen-hoffmann, Imaging human stratified squamous epithelia using nonlinear optical microscopy, Journal Of Investigative Dermatology, vol. 126 (April, 2006), ISSN 0022-202X
  60. G. M. Palmer and N. Ramanujam, Monte Carlo-based inverse model for calculating tissue optical properties. Part I: Theory and validation on synthetic phantoms, Applied Optics, vol. 45 no. 5 (February, 2006), pp. 1062 -- 1071, ISSN 0003-6935  [abs]
  61. G. M. Palmer and C. F. Zhu and T. M. Breslin and F. S. Xu and K. W. Gilchrist and N. Ramanujam, Monte Carlo-based inverse model for calculating tissue optical properties. Part II: Application to breast cancer diagnosis, Applied Optics, vol. 45 no. 5 (February, 2006), pp. 1072 -- 1078, ISSN 0003-6935  [abs]
  62. S. Chiles and K. Roldan-perez and K. Riching and G. Palmer and N. Ramanujam, Effect of optical clearing agents on the optical properties of squamous epithelial tissue, Lasers In Surgery And Medicine (2006), ISSN 0196-8092
  63. Quan Liu and Ramanujam, N., Sequential estimation of optical properties of a two-layered epithelial tissue model from depth-resolved ultraviolet-visible diffuse reflectance spectra, Appl. Opt. (USA), vol. 45 no. 19 (2006), pp. 4776 - 90 [AO.45.004776]  [abs]
  64. Palmer, G.M. and Ramanujam, N., Monte Carlo-based inverse model for calculating tissue optical properties. Part I: Theory and validation on synthetic phantoms, Appl. Opt. (USA), vol. 45 no. 5 (2006), pp. 1062 - 71 [AO.45.001062]  [abs]
  65. Palmer, G.M. and Changfang Zhu and Breslin, T.M. and Fushen Xu and Gilchrist, K.W. and Ramanujam, N., Monte Carlo-based inverse model for calculating tissue optical properties. Part II: Application to breast cancer diagnosis, Appl. Opt. (USA), vol. 45 no. 5 (2006), pp. 1072 - 8 [AO.45.001072]  [abs]
  66. Changfang Zhu and Palmer, G.M. and Breslin, T.M. and Fushen Xu and Ramanujam, N., Use of a multiseparation fiber optic probe for the optical diagnosis of breast cancer, J. Biomed. Opt. (USA), vol. 10 no. 2 (2005), pp. 24032 - 1 [1.1897398]  [abs]
  67. Palmer, G.M. and Changfang Zhu and Breslin, T.M. and Fushen Xu and Gilchrist, K.W. and Ramanujam, N., Comparison of multiexcitation fluorescence and diffuse reflectance spectroscopy for the diagnosis of breast cancer (March 2003), IEEE Trans. Biomed. Eng. (USA), vol. 50 no. 11 (2003), pp. 1233 - 42 [TBME.2003.818488]  [abs]
  68. Palmer, Gregory M. and Ramanujam, Nirmala, Diagnosis of Breast Cancer Using Optical Spectroscopy, Medical Laser Application, vol. 18 no. 3 (2003), pp. 233 - 248  [abs]
  69. Changfang Zhu and Quan Liu and Ramanujam, N., Effect of fiber optic probe geometry on depth-resolved fluorescence measurements from epithelial tissues: a Monte Carlo simulation, J. Biomed. Opt. (USA), vol. 8 no. 2 (2003), pp. 237 - 47 [1.1559058]  [abs]
  70. Quan Liu and Changfang Zhu and Ramanujam, N., Experimental validation of Monte Carlo modeling of fluorescence in tissues in the UV-visible spectrum, J. Biomed. Opt. (USA), vol. 8 no. 2 (2003), pp. 223 - 36 [1.1559057]  [abs]
  71. Liu Quan and Ramanujam, N., Relationship between depth of a target in a turbid medium and fluorescence measured by a variable-aperture method, Opt. Lett. (USA), vol. 27 no. 2 (2002), pp. 104 - 6  [abs]
  72. Yueqing Gu and Zhiyu Qian and Jinxian Chen and Blessington, D. and Ramanujam, N. and Chance, B., High-resolution three-dimensional scanning optical image system for intrinsic and extrinsic contrast agents in tissue, Rev. Sci. Instrum. (USA), vol. 73 no. 1 (2002), pp. 172 - 8 [1.1424907]  [abs]
  73. Cai, Y. and Ramanujam, N. and Morris, J.M. and Adali, T. and Lenner, G. and Puc, A.B. and Pilipetskii, A., Performance limit of forward error correction codes in optical fiber communications, Conference on Optical Fiber Communication, Technical Digest Series, vol. 54 no. 2 (2001), pp. 2 - 1, Anaheim, CA  [abs]
  74. Ramanujam, Nirmala and Richards-Kortum, Rebecca and Thomsen, Sharon and Mahadevan-Jansen, Anita and Follen, Michele and Chance, Britton, Low temperature fluorescence imaging of freeze-trapped human cervical tissues, Optics Express, vol. 8 no. 6 (2001), pp. 335 - 343  [abs]
  75. Vishnoi, G. and Choe, R. and Ramanujam, N. and Rode, M.E. and Chance, B., On-line monitoring of oxy- and deoxy-hemoglobin using near infra-red spectroscopic techniques, Proc. SPIE - Int. Soc. Opt. Eng. (USA), vol. 4417 (2001), pp. 493 - 9, Calcutta, India [12.441341]  [abs]
  76. Ramanujam, N. and Richards-Kortum, R. and Thomsen, S. and Mahadevan-Jansen, A. and Follen, M. and Chance, B., Low temperature fluorescence imaging of freeze-trapped human cervical tissues, Opt. Express (USA), vol. 8 no. 6 (2001)  [abs]
  77. Kidorf, H. and Ramanujam, N. and Hayee, I. and Nissov, M. and Cai, J.-X. and Pedersen, B. and Puc, A. and Rivers, C., Performance improvement in high capacity, ultra-long distance, WDM systems using forward error correction codes, Optical Fiber Communication Conference. Technical Digest Postconference Edition. Trends in Optics and Photonics Vol.37 (IEEE Cat. No. 00CH37079), vol. vol.3 (2000), pp. 274 - 6, Baltimore, MD, USA [OFC.2000.868589]  [abs]
  78. Ramanujam, N. and Lifeng Li and Burke, J.J., A novel design technique for mode control in multilayer waveguides, Trends in Optics and Photonics. Integrated Photonics Research. Vol.45. Technical Digest. Postconference Edition (2000), pp. 165 - 7, Quebec, Que., Canada  [abs]
  79. Jacques, S.L. and Ramanujam, N. and Vishnoi, G. and Choe, R. and Chance, B., Modeling photon transport in transabdominal fetal oximetry, J. Biomed. Opt. (USA), vol. 5 no. 3 (2000), pp. 277 - 82 [1.429996]  [abs]
  80. Vishnoi, G. and Hielscher, A.H. and Ramanujam, N. and Chance, B., Photon migration through fetal head in utero using continuous wave, near-infrared spectroscopy: development and evaluation of experimental and numerical models, J. Biomed. Opt. (USA), vol. 5 no. 2 (2000), pp. 163 - 72 [1.429983]  [abs]
  81. Ramanujam, N. and Vishnoi, G. and Hielscher, A. and Rode, M. and Forouzan, I. and Chance, B., Photon migration through fetal head in utero using continuous wave, near infrared spectroscopy: clinical and experimental model studies, J. Biomed. Opt. (USA), vol. 5 no. 2 (2000), pp. 173 - 84 [1.429984]  [abs]
  82. Natesan, S. and Ramanujam, N., Booster method for singularly-perturbed one-dimensional reaction-diffusion Neumann problems, J. Optim. Theory Appl. (USA), vol. 104 no. 1 (2000), pp. 175 - 94 [A:1004637024562]  [abs]
  83. Yazdi, Youseph and Ramanujam, Nirmala and Lotan, Reuben and Mitchell, Michele Follen and Hittelman, Walter and Richards-Kortum, Rebecca, Resonance Raman spectroscopy at 257 nm excitation of normal and malignant cultured breast and cervical cells, Applied Spectroscopy, vol. 53 no. 1 (1999), pp. 82 - 85 [0003702991945254]  [abs]
  84. Chance, B. and Cope, M. and Gratton, E. and Ramanujam, N. and Tromberg, B., Phase measurement of light absorption and scatter in human tissue, Rev. Sci. Instrum. (USA), vol. 69 no. 10 (1998), pp. 3457 - 81 [1.1149123]  [abs]
  85. Mahadevan-Jansen, Anita and Mitchell, Michele Follen and Ramanujam, Nirmala and Malpica, Anais and Thomsen, Sharon and Richards-Kortum, Rebecca, Near-infrared Raman spectroscopy for in vitro detection of cervical precancers, Photochemistry and Photobiology, vol. 68 no. 1 (1998), pp. 123 - [0031-8655(1998)068<0123:NIRSFV>2.3.CO;2]
  86. Mahadevan-Jansen, Anita and Mitchell, Michele Follen and Ramanujam, Nirmala and Utzinger, Urs and Richards-Kortum, Rebecca, Development of a fiber optic probe to measure NIR Raman spectra of cervical tissue in vivo, Photochemistry and Photobiology, vol. 68 no. 3 (1998), pp. 427 - [0031-8655(1998)068<0427:DOAFOP>2.3.CO;2]
  87. Ramanujam, N. and Du, C. and Ma, H.Y. and Chance, B., Sources of phase noise in homodyne and heterodyne phase modulation devices used for tissue oximetry studies, Rev. Sci. Instrum. (USA), vol. 69 no. 8 (1998), pp. 3042 - 54 [1.1149053]  [abs]
  88. Tumer, K. and Ramanujam, N. and Ghosh, J. and Richards-Kortum, R., Ensembles of radial basis function networks for spectroscopic detection of cervical precancer, IEEE Trans. Biomed. Eng. (USA), vol. 45 no. 8 (1998), pp. 953 - 61 [10.704864]  [abs]
  89. Trujillo, E.V. and Sandison, D.R. and Utzinger, U. and Ramanujam, N. and Mitchell, M.F. and Richards-Kortum, R., Method to determine tissue fluorescence efficiency in vivo and predict signal-to-noise ratio for spectrometers, Appl. Spectrosc. (USA), vol. 52 no. 7 (1998), pp. 943 - 51 [0003702981944751]  [abs]
  90. Ramanujam, Nirmala and Mitchell, Michele Follen and Mahadevan-Jansen, Anita and Thomsen, Sharon L. and Staerkel, Gregg and Malpica, Anais and Wright, Thomas and Atkinson, Neely and Richards-Kortum, Rebecca, Cervical precancer detection using a multivariate statistical algorithm based on laser-induced fluorescence spectra at multiple excitation wavelengths, Photochemistry and Photobiology, vol. 64 no. 4 (1996), pp. 720 -
  91. Richards-Kortum, R. and Mahadevan-Jansen, A. and Ramanujam, N., Optical spectroscopy vs. the surgical suite [cancer detection], IEEE Circuits Devices Mag. (USA), vol. 12 no. 4 (1996), pp. 34 - 40 [101.526878]  [abs]
  92. Mahadevan, Anita and Ramanujam, Nirmala and Mitchell, Michele F. M.D. and Malpica, Anais M.D. and Thomsen, Sharon L. M.D. and Richards-Kortum, Rebecca R., Optical techniques for diagnosis of cervical precancers: a comparison of Raman and fluorescence spectroscopies, Proceedings of SPIE - The International Society for Optical Engineering, vol. 2388 (1995), pp. 110 - 120, San Jose, CA, USA [12.208469]  [abs]
  93. Jayakumar, J. and Ramanujam, N., A computational method for solving quasilinear singular perturbation problems, Appl. Math. Comput. (USA), vol. 71 no. 1 (1995), pp. 1 - 14 [0096-3003(94)00077-H]  [abs]
  94. Jayakumar, J. and Ramanujam, N., A numerical method for singular perturbation problems arising in chemical reactor theory, Comput. Math. Appl. (UK), vol. 27 no. 5 (1994), pp. 83 - 99 [0898-1221(94)90078-7]  [abs]
  95. Durkin, A.J. and Jaikumar, S. and Ramanujam, N. and Richards-Kortum, R., Relation between fluorescence spectra of dilute and turbid samples, Appl. Opt. (USA), vol. 33 no. 3 (1994), pp. 414 - 23  [abs]
  96. Lubawy, C. and Ramanujam, N., Endoscopically compatible near-infrared photon migration probe, Opt. Lett. (USA), vol. 29 no. 17 (1), pp. 2022 - 4  [abs]
  97. Quan Liu and Ramanujam, N., Experimental proof of the feasibility of using an angled fiber-optic probe for depth-sensitive fluorescence spectroscopy of turbid media, Opt. Lett. (USA), vol. 29 no. 17 (1), pp. 2034 - 6 [OL.29.002034]  [abs]
  98. Ramanujam, N. and Jinxian Chen and Gossage, K. and Richards-Kortum, R. and Chance, B., Fast and noninvasive fluorescence imaging of biological tissues in vivo using a flying-spot scanner, IEEE Trans. Biomed. Eng. (USA), vol. 48 no. 9 , pp. 1034 - 41 [10.942594]  [abs]

Other

  1. Kennedy S, Mueller J, Bydlon T, Brown JQ, Ramanujam N, Using wide-field quantitative diffuse reflectance spectroscopy in combination with high-resolution imaging for margin assessment, Proc. of SPIE, Vol. 7890, San Francisco, CA. (2011)
  2. Chang VTC, Merisier D, Yu B, Walmer D, Ramanujam N, Calibration Schemes of a Field-compatible Optical Spectroscopic System to Quantify Neovascular Changes in the Dysplastic Cervix, Proc. of SPIE, Vol. 7890, San Francisco, CA. (2011)
  3. Brown JQ, Bydlon TM, Kennedy SA, Geradts J, Wilke LG, Richards LM, Junker M, Gallagher J, Ramanujam N, Assessment of breast tumor margins via quantitative spectral reflectance imaging, Invited paper, Biomedical Applications of Light Scattering IV, SPIE Photonics West - BIOS Conference Proceedings v. 7573, San Francisco, CA. (2010)
  4. Brown JQ, Yu B, Ramanujam N, Tissue-mimicking phantoms for system calibration and validation in Quantitative Diffuse Reflectance Spectroscopy (Q-DRS), Design and Performance Validation of Phantoms used in Conjunction with Optical Measurement of Tissue III, SPIE Photonics West - BIOS, San Francisco, CA. (2010)
  5. Lazebnik, M. and Changfang Zhu and Palmer, G. and Harter, J. and Sewall, S. and Ramanujam, N. and Hagness, S.C., Comparison of electromagnetic properties of normal breast tissue at optical and microwave frequencies, 2006 IEEE Antennas and Propagation Society International Symposium (IEEE Cat. No. 06CH37758C) (2006), pp. 397 -, Albuquerque, NM, USA  [abs]
  6. Choe, R. and Durduran, T. and Guoqiang Yu and Nijland, M.J.M. and Nathanielsz, P.W. and Chance, B. and Yodh, A.G. and Ramanujam, N., Noninvasive cerebral hemoglobin oxygenation quantification of fetal sheep under hypoxic stress in-utero using frequency-domain diffuse optical two-layer model, Proc. SPIE - Int. Soc. Opt. Eng. (USA), vol. 4955 no. 1 (2003), pp. 379 - 87, San Jose, CA, USA [12.478175]  [abs]
  7. Ramanujam, N. and Palmer, G. and Breslin, T. and Gichrist, K., Diagnosis of breast cancer using auto fluorescence and diffuse reflectance spectroscopy, Conference Proceedings. Second Joint EMBS-BMES Conference 2002. 24th Annual International Conference of the Engineering in Medicine and Biology Society. Annual Fall Meeting of the Biomedical Engineering Society (Cat. No.02CH37392), vol. vol.3 (2002), pp. 2279 - 80, Houston, TX, USA [IEMBS.2002.1053281]  [abs]
  8. Tompkins, W.J. and Beebe, D. and Gimm, J.A. and Nicosia, M. and Ramanujam, N. and Thompson, P. and Tyler, M.E. and Webster, J.G., A design backbone for the biomedical engineering curriculum, Conference Proceedings. Second Joint EMBS-BMES Conference 2002. 24th Annual International Conference of the Engineering in Medicine and Biology Society. Annual Fall Meeting of the Biomedical Engineering Society (Cat. No.02CH37392), vol. vol.3 (2002), pp. 2595 - 6, Houston, TX, USA [IEMBS.2002.1053443]  [abs]
  9. Vishnoi, G. and Choe, R. and Ramanujam, N. and Rode, M.E. and Nioka, S. and Chance, B., Quantification of fetal blood parameters using non-invasive optical techniques, Technical Digest. CLEO/Pacific Rim 2001. 4th Pacific Rim Conference on Lasers and Electro-Optics (Cat. No.01TH8557), vol. vol.1 (2001), pp. 380 - 1, Chiba, Japan [CLEOPR.2001.967884]  [abs]
  10. Ramanujam, N. and Puc, A.B. and Lenner, G. and Kidorf, H.D. and Davidson, C.R. and Hayee, I. and Cai, J.-X. and Nissov, M. and Pilipetskii, A. and Rivers, C. and Bergano, N.S., Forward error correction (FEC) techniques in long-haul optical transmission systems, LEOS 2000. 2000 IEEE Annual Meeting Conference Proceedings. 13th Annual Meeting. IEEE Lasers and Electro-Optics Society 2000 Annual Meeting (Cat. No.00CH37080), vol. vol.2 (2000), pp. 405 - 6, Rio Grande, Puerto Rico [LEOS.2000.893884]  [abs]
  11. Choe, Regine and Vishnoi, Gargi and Ramanujam, Nirmala and Ntziachristos, Vasilis and Nioka, Shoko and Chance, Britton and Yodh, Arjun G. and Rode, Martha and Forouzan, Iraj and Morgan, Mark, Feasibility of frequency domain NIR spectrometer to measure fetal cerebral blood oxygenation in-utero, Proceedings of SPIE - The International Society for Optical Engineering, vol. 3597 (1999), pp. 661 - 668, San Jose, CA, USA [12.356782]  [abs]
  12. Zourabian, A. and Siegel, A. and Ramanujam, N. and Chance, B. and Boas, D.A. and Vishnoi, B.G. and Choe, R., Non-invasive trans-abdominal monitoring of fetal cerebral oxygenation using pulse oximetry, Proceedings of SPIE - The International Society for Optical Engineering, vol. 3597 (1999), pp. 669 - 675, San Jose, CA, USA [12.356783]  [abs]
  13. Vishnoi, Gargi and Hielscher, Andreas H. and Ramanujam, Nirmala and Nioka, Shoko and Chance, Britton, Tissue phantom studies on photon migration through fetal brain in-utero using near infra-red spectroscopy, Proceedings of SPIE - The International Society for Optical Engineering, vol. 3597 (1999), pp. 650 - 660, San Jose, CA, USA [12.356788]  [abs]
  14. Trujillo, E.V. and Sandison, D. and Ramanujam, N. and Follen-Mitchell, M. and Cantor, S. and Richards-Kortum, R., Development of a cost-effective optical system for detection of cervical pre-cancer, Proceedings of the 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. `Bridging Disciplines for Biomedicine' (Cat. No.96CH36036), vol. vol.1 (1997), pp. 191 - 3, Amsterdam, Netherlands [IEMBS.1996.656911]  [abs]
  15. Tumer, K. and Ramanujam, N. and Richards-Kortum, R. and Ghosh, J., Spectroscopic detection of cervical pre-cancer through radial basis function networks, Advances in Neural Information Processing Systems 9. Proceedings of the 1996 Conference (1997), pp. 981 - 7, Denver, CO, USA  [abs]
  16. Ramanujam, Nirmala and Follen-Mitchell, Michele and Mahadevan-Jansen, Anita and Pitris, Costas and Agrawal, Anant and Thomsen, Sharon L. M.D. and Staerkel, Gregg and Wright, Thomas and Richards-Kortum, Rebecca R., Detection of cervical precancer using optical spectroscopy (Extended Abstract), Proceedings of SPIE - The International Society for Optical Engineering, vol. 2926 (1996), pp. 21 - 22, Vienna, Austria [12.260814]  [abs]
  17. Trujillo, E.V. and Sandison, D. and Ramanujam, N. and Follen-Mitchell, M. and Cantor, S. and Richards-Kortum, R., Development of a cost-effective optical system for detection of cervical pre-cancer, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings no. 1 (1996), pp. 191 - 193, Amsterdam, Neth  [abs]
  18. Ramanujam, N. and Burke, J.J. and Lifeng Li, Ferroelectric channel waveguides with high SHG conversion efficiency and non-critical phasematching characteristics, Proc. SPIE - Int. Soc. Opt. Eng. (USA), vol. 2700 (1996), pp. 130 - 9, San Jose, CA, USA  [abs]

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