Publications [#162121] of Nimmi Ramanujam
- B. Yu and H. Fu and T. Bydlon and J. E. Bender and N. Ramanujam, Diffuse reflectance spectroscopy with a self-calibrating fiber optic probe,
Optics Letters, vol. 33 no. 16
pp. 1783 -- 1785, ISSN 0146-9592
(last updated on 2009/09/02)
Calibration of the diffuse reflectance spectrum for instrument response and time-dependent fluctuation as well as interdevice variations is complicated, time consuming, and potentially inaccurate. We describe a novel fiber optic probe with a real-time self-calibration capability that can be used for tissue optical spectroscopy. The probe was tested in a number of liquid phantoms over a relevant range of tissue optical properties. Absorption and scattering coefficients are extracted with an average absolute error and standard deviation of 6.9\%+/- 7.2\% and 3.5\%+/- 1.5\%, respectively. (C) 2008 Optical Society of America.