Publications [#62301] of Nimmi Ramanujam

Papers Published

1. Quan Liu and Ramanujam, N., Experimental proof of the feasibility of using an angled fiber-optic probe for depth-sensitive fluorescence spectroscopy of turbid media, Opt. Lett. (USA), vol. 29 no. 17 (1), pp. 2034 - 6 [OL.29.002034]
   (last updated on 2007/04/13)

   Abstract:
   An angled fiber-optic probe that facilitates depth-sensitive fluorescence measurements was developed for enhancing detection of epithelial precancers. The probe was tested on solid, two-layered phantoms and proved to be effective in selectively detecting fluorescence from different layers. Specifically, a larger illumination angle provides greater sensitivity to fluorescence from the top layer as well as yielding an overall higher fluorescence signal. Monte Carlo simulations of a theoretical model of the phantoms demonstrate that increasing the illumination angle results in an increased excitation photon density and, thus, in increased fluorescence generated in the top layer

   Keywords:
   bio-optics;biomedical measurement;biomedical optical imaging;cancer;fibre optic sensors;fluorescence;Monte Carlo methods;phantoms;physiological models;skin;turbidity;