Publications [#62322] of Nimmi Ramanujam

Papers Published

1. Yazdi, Youseph and Ramanujam, Nirmala and Lotan, Reuben and Mitchell, Michele Follen and Hittelman, Walter and Richards-Kortum, Rebecca, Resonance Raman spectroscopy at 257 nm excitation of normal and malignant cultured breast and cervical cells, Applied Spectroscopy, vol. 53 no. 1 (1999), pp. 82 - 85 [0003702991945254]
   (last updated on 2007/04/13)

   Abstract:
   The sensitivity and selectivity of ultraviolet (UV)-excited resonance Raman spectroscopy indicate that this technique may be useful in studying certain biochemical changes in cells, especially changes in DNA that occur during the development of cancer. To determine whether this technique can distinguish normal from malignant cells, UV resonance Raman spectra at 257.26 nm excitation of suspensions of normal and malignant cultured breast and cervical samples were measured. Samples were excited using an intracavity doubled argon-ion laser, and the spectra were recorded with a single grating spectrograph and a liquid nitrogen-cooled charge-coupled device.

   Keywords:
   Ultraviolet spectroscopy;Oncology;Gynecology;Biochemistry;Cell culture;DNA;Laser applications;Spectrographs;Charge coupled devices;Cytology;