Publications [#131987] of James M Provenzale

Papers Published

1. JM Provenzale, DP Barboriak, TL Ortel, Dural sinus thrombosis associated with activated protein C resistance: MR imaging findings and proband identification., AJR. American journal of roentgenology, UNITED STATES, vol. 170 no. 2 (February, 1998), pp. 499-502, ISSN 0361-803X
   (last updated on 2007/02/06)

   Abstract:
   OBJECTIVE: The purpose of this study was to report the association of dural sinus thrombosis with a hypercoagulable state associated with activated protein C resistance. CONCLUSION: In our small study population, hemorrhagic venous infarction was common (three of four patients) among patients with dural sinus thrombosis and activated protein C resistance. Four of five patients with dural sinus thrombosis had positive tests for activated protein C resistance. This finding, in conjunction with data from other studies, suggests that patients with dural sinus thrombosis may need to be studied for the presence of activated protein C resistance. A positive finding for activated protein C resistance can be important not only in helping to explain the cause of thrombosis in affected individuals but also in identifying families at risk for thrombosis.

   Keywords:
   Adult • Dura Mater • Female • Genetic Predisposition to Disease • Humans • Magnetic Resonance Imaging* • Male • Protein C • Risk Factors • Sinus Thrombosis, Intracranial • blood • genetics* • pathology* • physiology*