Publications [#158212] of James M Provenzale
- JM Provenzale, M Wintermark, Optimization of perfusion imaging for acute cerebral ischemia: review of recent clinical trials and recommendations for future studies.,
AJR. American journal of roentgenology, vol. 191 no. 4
pp. 1263-70, ISSN 1546-3141 [doi]
(last updated on 2011/07/12)
OBJECTIVE: The use of thrombolytic agents and other forms of reperfusion therapy has provided a means to reverse ischemia and minimize the size of infarctions. The purpose of this review is to examine various clinical trials of reperfusion agents and address key imaging issues. CONCLUSION: Advanced MRI and CT play a growing role in selection of patients for therapy. Numerous clinical trials have shed light on the efficacy of various reperfusion therapies; disparities in trial design have also left unanswered questions.
Acute Disease • Brain Ischemia • Clinical Trials as Topic • Humans • Magnetic Resonance Imaging • Tomography, X-Ray Computed • diagnosis* • methods* • radiography