Publications [#192784] of James M Provenzale

Papers Published

1. AM Mohs, JM Provenzale, Applications of nanotechnology to imaging and therapy of brain tumors., Neuroimaging clinics of North America, vol. 20 no. 3 (August, 2010), pp. 283-92, ISSN 1557-9867 [doi]
   (last updated on 2013/05/16)

   Abstract:
   In the past decade, numerous advances in the understanding of brain tumor physiology, tumor imaging, and tumor therapy have been attained. In some cases, these advances have resulted from refinements of pre-existing technologies (eg, improvements of contrast-enhanced magnetic resonance imaging). In other instances, advances have resulted from development of novel technologies. The development of nanomedicine (ie, applications of nanotechnology to the field of medicine) is an example of the latter. In this review, the authors explain the principles that underlay nanoparticle design and function as well as the means by which nanoparticles can be used for imaging and therapy of brain tumors.

   Keywords:
   Animals • Blood-Brain Barrier • Brain • Brain Neoplasms • Drug Delivery Systems • Humans • Magnetic Resonance Imaging • Nanoparticles • Nanotechnology • Rats • diagnosis* • drug effects • methods • methods* • pathology • surgery • therapy*