- A. Hucknall and D. H. Kim and S. Rangarajan and R. T. Hill and W. M. Reichert and A. Chilkoti, Simple Fabrication of Antibody Microarrays on Nonfouling Polymer Brushes with Femtomolar Sensitivity for Protein Analytes in Serum and Blood,
Advanced Materials, vol. 21 no. 19
pp. 1968 -- 1971 .
(last updated on 2009/09/02)
A multianalyte antibody array that is spotted on a poly(oligo(ethylene glycol) methacrylate) brush 100 nm thick, grown on glass via surface-initiated atom transfer radical polymerization, has femtomolar limit-of-detection (LOD) of cytokines in serum and whole blood, and a dynamic range of six orders of magnitude for a range of protein analytes.