- Chilkoti, A. and Ratner, B.D. and Briggs, D., Structural elucidation of oxygen-containing plasma deposited films by static secondary ion mass spectrometry,
Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium, vol. 14
pp. 180 - .
(last updated on 2007/04/12)
This study focusses on the use of static secondary ion mass spectrometry (SIMS) to unravel the surface chemistry of oxygen-containing organic PDF of interest in cell growth applications. The aims of this study are (1) to elucidate the identity of secondary ions emitted from the PDF surface (2) relate these ions to structural features on the PDF surface (3) develop a quantitative model that is capable of predicting aspects of the surface structure of these PDF. This has been achieved by (1) analysis of stable-isotope labeled PDF to identify the PDF secondary ions, followed by (2) comparison of PDF spectra with appropriate model polymers to relate them to known structural features and (3) the use of multivariate statistical techniques to predict both the concentration of functional groups of interest and the various types of structural units that could be present on the PDF surface.
Films--Spectroscopic Analysis;Spectroscopy, X-ray;Spectroscopy, Photoelectron;Biological Materials--Cells;Polymers--Medical Applications;