- Yang, Zhongping and Chilkoti, Ashutosh, Microstamping of a biological ligand onto an activated polymer surface,
Advanced Materials, vol. 12 no. 6
pp. 413 - 417 [(SICI)1521-4095(200003)12:6<413::AID-ADMA413>3.0.CO;2-#] .
(last updated on 2007/04/12)
A method for patterning biological ligands and proteins were patterned onto polymer surfaces is described. Called microstamping onto an activated polymer surface (MAPS), the method is based on a reaction between a microcontact-printed biological ligand and the surface of a polymer that has been derivatized to react specifically with the ligand. Using biotin ligands and polyethylene terephthalate, the method was demonstrated to yield a spatial resolution of at least 5 µm, high contrast and good reproducibility.