- A. M. Ponce and A. Wright and M. W. Dewhirts and D. Needham, Targeted bioavailability of drugs by triggered release from liposomes,
Future Lipidology, vol. 1 no. 1
pp. 25 -- 34 .
(last updated on 2009/08/04)
The temperature-sensitive liposome is now in Phase I human clinical trials. This review will provide an update, recapping earlier work and presenting new data that show unexpected mechanistic features that make this triggered-release system an emerging new paradigm for local drug delivery.