- Corbitt, Thomas S. and Sommer, Jonathan R. and Chemburu, Sireesha and Ogawa, Katsu and Ista, Linnea K. and Lopez, Gabriel P. and Whitten, David G. and Schanze, Kirk S., Conjugated Polyelectrolyte Capsules: Light-Activated Antimicrobial Micro ``Roach Motels'',
ACS APPLIED MATERIALS & INTERFACES, vol. 1 no. 1
pp. 48--52 [doi] .
(last updated on 2010/02/08)
Microcapsules consisting of alternating layers of oppositely charged poly(phenylene ethynylene)-type conjugated polyelectrolytes (CPEs) were prepared via layer-by-layer deposition onto MnCO3 template particles followed by dissolution of the template particles using an ethylenediaminetetraacetate solution. The resulting microcapsules exhibit bright-green fluorescence emission characteristics of the CPEs. Strong antimicrobial activity was observed upon mixing Of polyelectrolyte capsules with Cobetia marina or Pseudomonas aeruginosa followed by white-light irradiation. It was demonstrated that the materials act as highly effective light-activated micro ``Roach Motels'' with greater than 95\% kill after exposure to similar to 1h of white light.