Papers Published

  1. Yu, Q. and Shivapooja, P. and Johnson, L. M. and Tizazu, G. and Leggett, G. J. and Lopez, G. P., Nanopatterned polymer brushes as switchable bioactive interfaces, Nanoscale, vol. 5 no. 9 (2013), pp. 3632--3637 [doi] .
    (last updated on 2013/06/21)

    We report convenient methods for synthesis of nanopatterned, thermally responsive brushes of poly(N-isopropyl acrylamide) over large areas (e.g., 1 cm(2)) to form model, dynamic, biofunctional surfaces. The new nanopatterned brush structure can be used to control (i) the rate of both nonspecific and biospecific adsorption processes at the polymer-graft-free regions of the substrate, and (ii) the rate of cell detachment. These capabilities have potential implications in a number of areas of biotechnology including biosensing, separations and cell culture.