- Kennedy, Laura C. and Bickford, Lissett R. and Lewinski, Nastassja A. and Coughlin, Andrew J. and Hu, Ying and Day, Emily S. and West, Jennifer L. and Drezek, Rebekah A., A New Era for Cancer Treatment: Gold-Nanoparticle-Mediated Thermal Therapies,
SMALL, vol. 7 no. 2
pp. 169--183 [doi] .
(last updated on 2012/02/23)
Nanotechnology-based cancer treatment approaches potentially provide localized, targeted therapies that aim to enhance efficacy, reduce side effects, and improve patient quality of life. Gold-nanoparticle-mediated hyperthermia shows particular promise in animal studies, and early clinical testing is currently underway. In this article, the rapidly evolving field of gold nanoparticle thermal therapy is reviewed, highlighting recent literature and describing current challenges to clinical translation of the technology.