- Li, J. and Ni, X. and Li, X. and Wang, X. and Zhou, Z. and Leong, K.W., A novel biodegradable amphiphilic triblock copolymer consisting of poly[(R)-β-hydroxybutyrate] and poly(ethylene oxide) and Its self-association property,
Transactions - 7th World Biomaterials Congress
pp. 1178 - .
(last updated on 2007/04/13)
The synthesis of a new polyethylene oxide (PEO) PHB-PEO triblock copolymers was discussed. It was observed that the resulting triblock copolymers have a strong tendency toward micelle formation in aqueous medium. The micelles formed with the PEO-PHB-PEO triblock copolymers were stable and readily handled. The results show the synthesis of amphiphilic PEO-PHB-PEO triblock copolymers and their micelle formation was unexpectedly found to be thermosensitive.
Biodegradation;Polyethylene oxides;Association reactions;Polyesters;Biopolymers;Hydrophobicity;Critical micelle concentration;Crystalline materials;Molecular weight;Fluorescence;Precipitation (chemical);Nuclear magnetic resonance spectroscopy;Fourier transform infrared spectroscopy;