- Salem, Aliasger K. and Searson, Peter C. and Leong, Kam W., Multifunctional nanorods for gene delivery,
Materials Research Society Symposium Proceedings, vol. EXS no. 1
pp. 455 - 457 .
(last updated on 2007/04/13)
The potential of multi-segment metallic nanorods in gene delivery system were investigated to achieve the control of size and composition by inorganic synthesis. Au/Ni nanorods were deposited by template synthesis method, which involved electrochemical deposition into a non-conducting membrane with an array of cylindrical pores. The nanorods were then used for the synthesis of a wide range of materials and structures. The unique properties of the nanorods that allow for defined aspect ratios and the addition of magnetic segments were utilized as a probe to determine the effects and inter-relationships of size, magnetism and cell targeting proteins in gene delivery.
Genetic engineering;Drug products;Genes;Synthesis (chemical);Gold compounds;Electrochemistry;Etching;Cell membranes;DNA;Energy dispersive spectroscopy;Transmission electron microscopy;Ultraviolet spectroscopy;