Papers Published

  1. Hochmuth, R.M. and Evans, E.A., Extensional flow of erythrocyte membrane from cell body to elastic tether. I. Analysis, Biophys. J. (USA), vol. 39 no. 1 (1982), pp. 71 - 81 .
    (last updated on 2007/04/10)

    It is shown that an application of the principle of conservation of mass permits the tether radius (~200 Å or less) to be measured with a light microscope as the tether is formed and extended at a constant rate. A static analysis of the axisymmetric cell deformation and tether formation process reveals that the tether radius is uniquely determined by the isotropic tension in the membrane and the elastic constitutive (material) behavior of the tether itself. A dynamic analysis of the extensional flow process reveals that the tether radius must decrease as the velocity of the tether is increased and that the decrease depends on both the viscosity of the membrane and the elasticity of the tether. The analysis also shows that these two factors (membrane viscosity and tether elasticity) are readily decomposed and determined separately when flow experiments are performed at different isotropic tensions

    biomembranes;biorheology;blood;cellular transport and dynamics;