Papers Published

  1. Hochmuth, R. M. and Mohandas, N., UNIAXIAL LOADING OF THE RED-CELL MEMBRANE., Journal of Biomechanics, vol. 5 no. 5 (1972), pp. 501 - 509 [0021-9290(72)90007-3] .
    (last updated on 2007/04/10)

    The overall strain in the direction of flow of human red blood cells which adhere to a glass surface is measured for a fluid shear stress at the surface between 1 and 10 dyn/cm**2. At a given shear stress, the overall strain depends on the width of attachment of the cell at the leading (upstream) edge and the strain increases with decreasing width of attachment. At a shear stress of 10 dyn/cm**2, overall strains as high as 60 per cent are observed for small widths of attachment. An analysis of cell deformation as a function of shear stress gives a modulus of elasticity for cell membrane of approximately 10**4 dyn/cm**2 if a membrane thickness of 0. 01 mu m is assumed.