- Guilak, Farshid and Ting-Beall, H. Ping and Baer, Anthony E. and Erickson, Geoffrey R. and Jones, Wendy R. and Pearsall, Richard L. and Setton, Lori A., Identification of two biomechanically distinct cell populations in the intervertebral disc,
American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, vol. 42
pp. 337 - 338 .
(last updated on 2007/04/10)
A study was carried out to quantify the morphology and the viscoelastic mechanical properties of isolated cells from the anulus fibrosus (AF), transition zone (TZ), and nucleus pulposus (NP) and to examine the hypothesis that cellular properties may influence the biophysical environment of the cells. Pronounced differences were observed in the morphology of the NP cells as compared to the AF and TZ cells. Evidence was obtained concerning the existence of two biomechanically distinct cell populations in the intervertebral disc (IVD).
Biomechanics;Bone;Cell culture;Proteins;Microscopic examination;Mathematical models;Regression analysis;