- Baer, Anthony E. and Laursen, Tod A. and Setton, Lori A., A finite-deformation, anisotropic, biphasic finite element model of cell-matrix interactions in the intervertebral disc,
American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, vol. 50
pp. 799 - 800 .
(last updated on 2007/04/10)
The finite deformation, anisotropic, biphasic finite element model of cell matrix interactions in the intervertebral disc was discussed. The model was used as a reference for validation of the nonlinear FEM predictions at equilibrium. The results suggested that zonal differences in cell micromechanical environment play a role in known differences in the biosynthetic response of the disc cells.
Deformation;Anisotropy;Strain;Stress relaxation;Computational complexity;Finite element method;