Papers Published

  1. Setton, L.A. and Zhu, W. and Mow, V.C., The biphasic poroviscoelastic behavior of articular cartilage: role of the surface zone in governing the compressive behavior, J. Biomech. (UK), vol. 26 no. 4-5 (1993), pp. 581 - 92 .
    (last updated on 2007/04/10)

    To assess the influence of the surface zone on the viscoelastic properties of cartilage under compressive loading, the authors prepared osteochondral plugs from skeletally mature steers, with and without the surface zone of articular cartilage, for study in the confined compression creep experiment. The relative contributions of two viscoelastic mechanisms, i.e. a flow-independent mechanism (Hayes and Bodine, ibid., vol.11, p407-19, 1978), and a flow-dependent mechanism (Mow et al., J. Biomech. Engng. ibid., vol.102, p.73-84, 1980), to the compressive creep response of these two types of specimens were determined using the biphasic poroviscoelastic theory proposed by (Mak., ibid., vol.20, p.703-14, 1986). From the experimental results and the biphasic poroviscoelastic theory, the authors found that frictional drag associated with interstitial fluid flow and fluid pressurization are the dominant mechanisms of load support in the intact specimens, i.e. the flow-dependent mechanisms alone with sufficient to describe normal articular cartilage compressive creep behavior. For specimens with the surface removed, the authors found an increased creep rate which was derived from an increased tissue permeability, as well as significant changes in the flow-independent parameters of the viscoelastic solid matrix