- Yang, Ye and Erb, Randall M. and Wiley, Benjamin J. and Zauscher, Stefan and Yellen, Benjamin B., Imaginary Magnetic Tweezers for Massively Parallel Surface Adhesion Spectroscopy,
NANO LETTERS, vol. 11 no. 4
pp. 1681-1684 [doi] .
(last updated on 2011/08/19)
A massively parallel magnetic tweezer system has been constructed that utilizes the self-repulsion of colloidal beads from a planar interface via a magnetic dipole image force. Self repulsion enables the application of a uniform magnetic force to thousands of beads simultaneously, which permits the measurement of unbinding histograms at the lowest loading rates ever tested. The adhesion of 9.8 mu m polystyrene beads to a fluorocarbon, PEG, and UV-irradiated PEG surfaces were measured between 10(-3)-10 degrees pN/s force loading rates, revealing the presence of both kinetic and quasi-equilibrium unbinding regimes.