Psychology and Neuroscience : Publications since January 2023
%% Adcock, Rachel A.
@article{fds373515,
Author = {Hsiung, A and Poh, J-H and Huettel, SA and Adcock,
RA},
Title = {Curiosity evolves as information unfolds.},
Journal = {Proc Natl Acad Sci U S A},
Volume = {120},
Number = {43},
Pages = {e2301974120},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1073/pnas.2301974120},
Abstract = {When people feel curious, they often seek information to
resolve their curiosity. Reaching resolution, however, does
not always occur in a single step but instead may follow the
accumulation of information over time. Here, we investigated
changes in curiosity over a dynamic information-gathering
process and how these changes related to affective and
cognitive states as well as behavior. Human participants
performed an Evolving Line Drawing Task, during which they
reported guesses about the drawings' identities and made
choices about whether to keep watching. In Study 1, the
timing of choices was predetermined and externally imposed,
while in Study 2, participants had agency in the timing of
guesses and choices. Using this dynamic paradigm, we found
that even within a single information-gathering episode,
curiosity evolved in concert with other emotional states and
with confidence. In both studies, we showed that the
relationship between curiosity and confidence depended on
stimulus entropy (unique guesses across participants) and on
guess accuracy. We demonstrated that curiosity is
multifaceted and can be experienced as either positive or
negative depending on the state of information gathering.
Critically, even when given the choice to alleviate
uncertainty immediately (i.e., view a spoiler), higher
curiosity promoted continuing to engage in the
information-gathering process. Collectively, we show that
curiosity changes over information accumulation to drive
engagement with external stimuli, rather than to shortcut
the path to resolution, highlighting the value inherent in
the process of discovery.},
Doi = {10.1073/pnas.2301974120},
Key = {fds373515}
}
@article{fds372794,
Author = {Wang, YC and Adcock, RA and Egner, T},
Title = {Toward an integrative account of internal and external
determinants of event segmentation.},
Journal = {Psychon Bull Rev},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.3758/s13423-023-02375-2},
Abstract = {Our daily experiences unfold continuously, but we remember
them as a series of discrete events through a process called
event segmentation. Prominent theories of event segmentation
suggest that event boundaries in memory are triggered by
significant shifts in the external environment, such as a
change in one's physical surroundings. In this review, we
argue for a fundamental extension of this research field to
also encompass internal state changes as playing a key role
in structuring event memory. Accordingly, we propose an
expanded taxonomy of event boundary-triggering processes,
and review behavioral and neuroscience research on internal
state changes in three core domains: affective states, goal
states, and motivational states. Finally, we evaluate how
well current theoretical frameworks can accommodate the
unique and interactive contributions of internal states to
event memory. We conclude that a theoretical perspective on
event memory that integrates both external environment and
internal state changes allows for a more complete
understanding of how the brain structures experiences, with
important implications for future research in cognitive and
clinical neuroscience.},
Doi = {10.3758/s13423-023-02375-2},
Key = {fds372794}
}
@article{fds371224,
Author = {Sinclair, AH and Wang, YC and Adcock, RA},
Title = {Instructed motivational states bias reinforcement learning
and memory formation.},
Journal = {Proc Natl Acad Sci U S A},
Volume = {120},
Number = {31},
Pages = {e2304881120},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1073/pnas.2304881120},
Abstract = {Motivation influences goals, decisions, and memory
formation. Imperative motivation links urgent goals to
actions, narrowing the focus of attention and memory.
Conversely, interrogative motivation integrates goals over
time and space, supporting rich memory encoding for flexible
future use. We manipulated motivational states via cover
stories for a reinforcement learning task: The imperative
group imagined executing a museum heist, whereas the
interrogative group imagined planning a future heist.
Participants repeatedly chose among four doors, representing
different museum rooms, to sample trial-unique paintings
with variable rewards (later converted to bonus payments).
The next day, participants performed a surprise memory test.
Crucially, only the cover stories differed between the
imperative and interrogative groups; the reinforcement
learning task was identical, and all participants had the
same expectations about how and when bonus payments would be
awarded. In an initial sample and a preregistered
replication, we demonstrated that imperative motivation
increased exploitation during reinforcement learning.
Conversely, interrogative motivation increased directed (but
not random) exploration, despite the cost to participants'
earnings. At test, the interrogative group was more accurate
at recognizing paintings and recalling associated values. In
the interrogative group, higher value paintings were more
likely to be remembered; imperative motivation disrupted
this effect of reward modulating memory. Overall, we
demonstrate that a prelearning motivational manipulation can
bias learning and memory, bearing implications for
education, behavior change, clinical interventions, and
communication.},
Doi = {10.1073/pnas.2304881120},
Key = {fds371224}
}
@article{fds373427,
Author = {Sinclair, AH and Taylor, MK and Brandel-Tanis, F and Davidson, A and Chande, AT and Rishishwar, L and Andris, C and Adcock, RA and Weitz, JS and Samanez-Larkin, GR and Beckett, SJ},
Title = {Communicating COVID-19 exposure risk with an interactive
website counteracts risk misestimation.},
Journal = {PLoS One},
Volume = {18},
Number = {10},
Pages = {e0290708},
Year = {2023},
url = {http://dx.doi.org/10.1371/journal.pone.0290708},
Abstract = {During the COVID-19 pandemic, individuals depended on risk
information to make decisions about everyday behaviors and
public policy. Here, we assessed whether an interactive
website influenced individuals' risk tolerance to support
public health goals. We collected data from 11,169 unique
users who engaged with the online COVID-19 Event Risk Tool
(https://covid19risk.biosci.gatech.edu/) between 9/22/21 and
1/22/22. The website featured interactive elements,
including a dynamic risk map, survey questions, and a risk
quiz with accuracy feedback. After learning about the risk
of COVID-19 exposure, participants reported being less
willing to participate in events that could spread COVID-19,
especially for high-risk large events. We also uncovered a
bias in risk estimation: Participants tended to overestimate
the risk of small events but underestimate the risk of large
events. Importantly, even participants who voluntarily
sought information about COVID risks tended to misestimate
exposure risk, demonstrating the need for intervention.
Participants from liberal-leaning counties were more likely
to use the website tools and more responsive to feedback
about risk misestimation, indicating that political
partisanship influences how individuals seek and engage with
COVID-19 information. Lastly, we explored temporal dynamics
and found that user engagement and risk estimation
fluctuated over the course of the Omicron variant outbreak.
Overall, we report an effective large-scale method for
communicating viral exposure risk; our findings are relevant
to broader research on risk communication, epidemiological
modeling, and risky decision-making.},
Doi = {10.1371/journal.pone.0290708},
Key = {fds373427}
}
%% Appelbaum, Lawrence G.
@article{fds367627,
Author = {Subramaniam, A and Liu, S and Lochhead, L and Appelbaum,
LG},
Title = {A systematic review of transcranial direct current
stimulation on eye movements and associated psychological
function.},
Journal = {Rev Neurosci},
Volume = {34},
Number = {3},
Pages = {349-364},
Publisher = {WALTER DE GRUYTER GMBH},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1515/revneuro-2022-0082},
Abstract = {The last decades have seen a rise in the use of transcranial
direct current stimulation (tDCS) approaches to modulate
brain activity and associated behavior. Concurrently, eye
tracking (ET) technology has improved to allow more precise
quantitative measurement of gaze behavior, offering a window
into the mechanisms of vision and cognition. When combined,
tDCS and ET provide a powerful system to probe brain
function and measure the impact on visual function, leading
to an increasing number of studies that utilize these
techniques together. The current pre-registered, systematic
review seeks to describe the literature that integrates
these approaches with the goal of changing brain activity
with tDCS and measuring associated changes in eye movements
with ET. The literature search identified 26 articles that
combined ET and tDCS in a probe-and-measure model and are
systematically reviewed here. All studies implemented
controlled interventional designs to address topics related
to oculomotor control, cognitive processing, emotion
regulation, or cravings in healthy volunteers and patient
populations. Across these studies, active stimulation
typically led to changes in the number, duration, and timing
of fixations compared to control stimulation. Notably, half
the studies addressed emotion regulation, each showing
hypothesized effects of tDCS on ET metrics, while tDCS
targeting the frontal cortex was widely used and also
generally produced expected modulation of ET. This review
reveals promising evidence of the impact of tDCS on eye
movements and associated psychological function, offering a
framework for effective designs with recommendations for
future studies.},
Doi = {10.1515/revneuro-2022-0082},
Key = {fds367627}
}
@article{fds367447,
Author = {Bukhari-Parlakturk, N and Lutz, MW and Al-Khalidi, HR and Unnithan,
S and Wang, JE-H and Scott, B and Termsarasab, P and Appelbaum, LG and Calakos, N},
Title = {Suitability of Automated Writing Measures for Clinical Trial
Outcome in Writer's Cramp.},
Journal = {Mov Disord},
Volume = {38},
Number = {1},
Pages = {123-132},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1002/mds.29237},
Abstract = {BACKGROUND: Writer's cramp (WC) dystonia is a rare disease
that causes abnormal postures during the writing task.
Successful research studies for WC and other forms of
dystonia are contingent on identifying sensitive and
specific measures that relate to the clinical syndrome and
achieve a realistic sample size to power research studies
for a rare disease. Although prior studies have used writing
kinematics, their diagnostic performance remains unclear.
OBJECTIVE: This study aimed to evaluate the diagnostic
performance of automated measures that distinguish subjects
with WC from healthy volunteers. METHODS: A total of 21
subjects with WC and 22 healthy volunteers performed a
sentence-copying assessment on a digital tablet using
kinematic and hand recognition softwares. The sensitivity
and specificity of automated measures were calculated using
a logistic regression model. Power analysis was performed
for two clinical research designs using these measures. The
test and retest reliability of select automated measures was
compared across repeat sentence-copying assessments. Lastly,
a correlational analysis with subject- and clinician-rated
outcomes was performed to understand the clinical meaning of
automated measures. RESULTS: Of the 23 measures analyzed,
the measures of word legibility and peak accelerations
distinguished subjects with WC from healthy volunteers with
high sensitivity and specificity and demonstrated smaller
sample sizes suitable for rare disease studies, and the
kinematic measures showed high reliability across repeat
visits, while both word legibility and peak accelerations
measures showed significant correlations with the subject-
and clinician-rated outcomes. CONCLUSIONS: Novel automated
measures that capture key aspects of the disease and are
suitable for use in clinical research studies of WC dystonia
were identified. © 2022 International Parkinson and
Movement Disorder Society.},
Doi = {10.1002/mds.29237},
Key = {fds367447}
}
@article{fds369099,
Author = {Ho, J and Liu, S and Feng, Z and Appelbaum, LG},
Title = {Psychomotor and visual skills underlying position
specialization in 1352 elite youth baseball
players.},
Journal = {Plos One},
Volume = {18},
Number = {1},
Pages = {e0278689},
Publisher = {Public Library of Science (PLoS)},
Editor = {Gu, Y},
Year = {2023},
url = {http://dx.doi.org/10.1371/journal.pone.0278689},
Abstract = {Baseball is an international sport with participation from
tens of thousands of people worldwide. In the United States,
the Prospect Development Pipeline (PDP) is a collaborative
effort between Major League Baseball and USA Baseball to
establish a developmental pipeline leading to the
professional draft. Players participating in the PDP undergo
comprehensive evaluations that measure athletic performance,
speed-of-processing, visual function, and on-field talent.
The present study evaluated data from 1352 elite junior male
PDP participants (aged 14 to 21) who signed informed
consent, collected between 2017 and 2020, to identify latent
abilities and their association with player specialization.
Data were first subjected to Exploratory Factor Analysis
(EFA) to reduce the 22 measured variables to a smaller set
of latent abilities. The resulting factors were evaluated
using multiple linear regression to predict each factor
using age, height, weight, and position. EFA revealed a
combination of physical and psychomotor skills accounting
for 52% of the overall variance that grouped into four
abilities: grip strength, functional vision, explosiveness,
and rapid decision-making. Regression analyses demonstrated
that these skills are associated with position assignments,
controlling for age, weight, and height, and revealed that
outfielders are the most explosive, infielders perform best
on psychomotor measures, and catchers perform best on
functional vision tests (ps < 0.001). These findings
indicate skills that contribute to player specialization,
providing new information about the developmental trajectory
of junior elite baseball athletes that can be used for
scouting and player development.},
Doi = {10.1371/journal.pone.0278689},
Key = {fds369099}
}
%% Arthur, Sarah
@article{fds375163,
Author = {Coleman, JN and Arthur, SS and Shelby, RA},
Title = {Psychological distress and pain related to gynecologic exams
among female survivors of sexual and physical violence: A
systematic review.},
Journal = {J Trauma Stress},
Volume = {37},
Number = {2},
Pages = {217-230},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1002/jts.23006},
Abstract = {Gender-based violence is prevalent globally, yet the impacts
of sexual and physical violence on women's experiences of
routine gynecologic care are not well understood. The
purpose of this systematic review of quantitative research
is to describe (a) psychological distress and pain related
to gynecologic exams among female survivors of sexual and
physical violence and (b) differences in distress or pain
between survivors and women without this history. Fourteen
articles based on 12 discrete studies met the inclusion
criteria. Studies were heterogeneous, with a moderate risk
of bias; therefore, a descriptive summary approach was
utilized rather than a meta-analytic approach. Synthesized
results indicated that survivors of violence experience
mild-to-severe levels of distress and mild-to-moderate
levels of pain related to gynecologic exams. The findings
suggest that survivors of sexual or physical violence
experience higher levels of distress than women without this
history (i.e., moderate to severe), and this difference was
further accentuated among women with more severe
posttraumatic stress symptoms (PTSS). Differences in pain by
violence history and PTSS severity were not consistently
observed, possibly due to a lack of variability in ratings
and small sample sizes. Additional research is needed that
bolsters the measurement of exam-related distress and pain,
adjusts for confounding variables, and explores mechanisms
by which sexual and physical violence impact care
experiences. Further empirical work will be critical to
developing interventions at the patient and provider levels
to improve women's experiences of care.},
Doi = {10.1002/jts.23006},
Key = {fds375163}
}
@article{fds375164,
Author = {Martin, S and Arthur, SS and Bovbjerg, DH and Huang, M and Keefe, FJ and Manculich, J and Soo, MSC and Zuley, ML and Shelby,
RA},
Title = {The Role Of Psychological Factors As Predictors Of
Mammography Pain Experienced By Breast Cancer Survivors
During Their First Surveillance Screening After
Breast-Conserving Surgery},
Journal = {JOURNAL OF PAIN},
Volume = {24},
Number = {4},
Pages = {100-100},
Year = {2023},
Key = {fds375164}
}
%% Asher, Steven R.
@article{fds376111,
Author = {Cerda-Smith, J and Yust, PKS and Weeks, MS and Asher, SR and Mulvey,
KL},
Title = {A Novel Approach for Evaluating a Schoolwide Antiracist
Curriculum Intervention},
Journal = {AERA Open},
Volume = {10},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1177/23328584231223476},
Abstract = {This manuscript describes our effort to apply a novel
approach to understanding student outcomes associated with a
schoolwide antiracist intervention. We report a multimethod
quantitative approach to evaluate a 10-week antiracist
intervention designed and implemented by school staff by
examining patterns of student intervention engagement and
measures of key constructs that connect to antiracism,
psychological well-being, and school connectedness. Our
novel approach combines schoolwide surveys with smaller
samples of daily diary participants, documenting variation
in intervention engagement and examining postintervention
outcomes. Our findings are limited by high attrition rates,
small sample size, and data collection during the COVID-19
pandemic; however, our methods offer a promising
transferable approach to evaluate school-based antiracist
interventions by examining patterns and predictors of
intervention engagement, as well as daily fluctuations in
student experience throughout the intervention
period.},
Doi = {10.1177/23328584231223476},
Key = {fds376111}
}
@article{fds371504,
Author = {Yust, PKS and Weeks, MS and Williams, GA and Asher,
SR},
Title = {Social relationship provisions and loneliness in school:
Child- and classroom-level effects.},
Journal = {Journal of school psychology},
Volume = {99},
Pages = {101218},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1016/j.jsp.2023.05.001},
Abstract = {Building on social needs theory (Weiss, 1974), this study
introduces the construct of classroom provision richness and
examines the association between the exchange of social
provisions among children in classrooms and children's
feelings of loneliness in school. We examined the receipt of
provisions from reciprocally nominated friends versus
unilateral (one-sided) and non-friend classmates and
examined associations between social provisions and
loneliness at the child and classroom levels. Participants
were 998 third- through fifth-grade children (468 girls, 530
boys; 88.5% White) in 38 classrooms who indicated which
classmates they played with, helped, validated, and provided
opportunities for self-disclosure. In addition to the social
provisions nomination measure, children responded to (a) a
measure of loneliness that avoided content overlapping with
social provisions, (b) a rating-scale sociometric measure of
peer acceptance, and (c) a measure that asked them to
indicate which classmates engaged in prosocial, aggressive,
or withdrawn-type behaviors. Multilevel analyses indicated
that social provisions received from reciprocal friends and
from unilateral-received friends were associated with
children's feelings of loneliness in school. Furthermore, a
measure of the provision richness of classrooms moderated
the association between child-level provisions received and
feelings of loneliness, such that children who received
fewer provisions were less lonely in classrooms that were
more provision-rich. Classroom provision richness was also
associated with the general level of prosocial behavior and
peer acceptance in the classroom. Together, findings suggest
that efforts to foster the exchange of social provisions in
classrooms could reduce loneliness and facilitate a more
caring classroom environment.},
Doi = {10.1016/j.jsp.2023.05.001},
Key = {fds371504}
}
%% Babinski, Leslie M
@article{fds373884,
Author = {Synergy for the Influence of the Month of Birth in ADHD
(SIMBA) study group},
Title = {Association between relative age at school and persistence
of ADHD in prospective studies: an individual participant
data meta-analysis.},
Journal = {Lancet Psychiatry},
Volume = {10},
Number = {12},
Pages = {922-933},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1016/S2215-0366(23)00272-9},
Abstract = {BACKGROUND: The youngest children in a school class are more
likely than the oldest to be diagnosed with ADHD, but this
relative age effect is less frequent in older than in
younger school-grade children. However, no study has
explored the association between relative age and the
persistence of ADHD diagnosis at older ages. We aimed to
quantify the association between relative age and
persistence of ADHD at older ages. METHODS: For this
meta-analysis, we searched MEDLINE, Embase, CINAHL,
PsycINFO, and PubPsych up to April 1, 2022, with terms
related to "cohort" and "ADHD" with no date, publication
type, or language restrictions. We gathered individual
participant data from prospective cohorts that included at
least ten children identified with ADHD before age 10 years.
ADHD was defined by either a clinical diagnosis or symptoms
exceeding clinical cutoffs. Relative age was recorded as the
month of birth in relation to the school-entry cutoff date.
Study authors were invited to share raw data or to apply a
script to analyse data locally and generate anonymised
results. Our outcome was ADHD status at a diagnostic
reassessment, conducted at least 4 years after the initial
assessment and after age 10 years. No information on sex,
gender, or ethnicity was collected. We did a two-stage
random-effects individual participant data meta-analysis to
assess the association of relative age with persistence of
ADHD at follow-up. This study was registered with PROSPERO,
CRD42020212650. FINDINGS: Of 33 119 studies generated by
our search, we identified 130 eligible unique studies and
were able to gather individual participant data from 57
prospective studies following up 6504 children with ADHD.
After exclusion of 16 studies in regions with a flexible
school entry system that did not allow confident linkage of
birthdate to relative age, the primary analysis included 41
studies in 15 countries following up 4708 children for a
period of 4 to 33 years. We found that younger relative age
was not statistically significantly associated with ADHD
persistence at follow-up (odds ratio 1·02, 95% CI
0·99-1·06; p=0·19). We observed statistically significant
heterogeneity in our model (Q=75·82, p=0·0011, I2=45%).
Participant-level sensitivity analyses showed similar
results in cohorts with a robust relative age effect at
baseline and when restricting to cohorts involving children
with a clinical diagnosis of ADHD or with a follow-up
duration of more than 10 years. INTERPRETATION: The
diagnosis of ADHD in younger children in a class is no more
likely to be disconfirmed over time than that of older
children in the class. One interpretation is that the
relative age effect decreases the likelihood of children of
older relative age receiving a diagnosis of ADHD, and
another is that assigning a diagnostic label of ADHD leads
to unexplored carryover effects of the initial diagnosis
that persist over time. Future studies should be conducted
to explore these interpretations further. FUNDING:
None.},
Doi = {10.1016/S2215-0366(23)00272-9},
Key = {fds373884}
}
@article{fds370921,
Author = {Babinski, LM and Murray, DW and Hamm, JV},
Title = {Self-Regulation Challenges and Supports in Middle Level
Education: Health Education Teachers’ and School
Counselors’ Views},
Journal = {RMLE Online},
Volume = {46},
Number = {6},
Pages = {1-16},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/19404476.2023.2204780},
Abstract = {Adolescents are in a dynamic period of cognitive, emotional,
and behavioral development. School-based interventions that
focus on social-emotional learning, including the
development of self-regulation skills, have been shown to
have positive impacts on students’ mental health and
academic achievement. In this qualitative study, we examine
health education teachers’ and school counselors’ views
of their students’ challenges and their strategies for
supporting students’ social and emotional development. We
conducted 16 focus groups and interviews with 24 educators:
16 middle level health education teachers and eight school
counselors. Our qualitative analysis of the transcripts
indicated that both teachers and counselors described the
contexts for students’ challenges as related to
academic/school pressures, social media, peer relationships,
and home influences. Educators also identified students’
challenges as being related to their developmental stage,
challenges with impulsive behaviors, and difficulty
regulating emotions. Strategies for supporting students’
self-regulation included day-to-day interactions, skills
instruction and practice, positive teacher-student
relationships, and a structured classroom environment.
Implications for professional development for middle level
educators and the implementation of preventive interventions
are discussed.},
Doi = {10.1080/19404476.2023.2204780},
Key = {fds370921}
}
%% Bagdasarov, Armen
@article{fds376293,
Author = {Bagdasarov, A and Brunet, D and Michel, CM and Gaffrey,
MS},
Title = {Microstate Analysis of Continuous Infant EEG: Tutorial and
Reliability.},
Journal = {Brain topography},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1007/s10548-024-01043-5},
Abstract = {Microstate analysis of resting-state EEG is a unique
data-driven method for identifying patterns of scalp
potential topographies, or microstates, that reflect stable
but transient periods of synchronized neural activity
evolving dynamically over time. During infancy - a critical
period of rapid brain development and plasticity -
microstate analysis offers a unique opportunity for
characterizing the spatial and temporal dynamics of brain
activity. However, whether measurements derived from this
approach (e.g., temporal properties, transition
probabilities, neural sources) show strong psychometric
properties (i.e., reliability) during infancy is unknown and
key information for advancing our understanding of how
microstates are shaped by early life experiences and whether
they relate to individual differences in infant abilities. A
lack of methodological resources for performing microstate
analysis of infant EEG has further hindered adoption of this
cutting-edge approach by infant researchers. As a result, in
the current study, we systematically addressed these
knowledge gaps and report that most microstate-based
measurements of brain organization and functioning except
for transition probabilities were stable with four minutes
of video-watching resting-state data and highly internally
consistent with just one minute. In addition to these
results, we provide a step-by-step tutorial, accompanying
website, and open-access data for performing microstate
analysis using a free, user-friendly software called
Cartool. Taken together, the current study supports the
reliability and feasibility of using EEG microstate analysis
to study infant brain development and increases the
accessibility of this approach for the field of
developmental neuroscience.},
Doi = {10.1007/s10548-024-01043-5},
Key = {fds376293}
}
@article{fds374968,
Author = {Bagdasarov, A and Roberts, K and Brunet, D and Michel, CM and Gaffrey,
MS},
Title = {Exploring the Association Between EEG Microstates During
Resting-State and Error-Related Activity in Young
Children.},
Journal = {Brain topography},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1007/s10548-023-01030-2},
Abstract = {The error-related negativity (ERN) is a negative deflection
in the electroencephalography (EEG) waveform at
frontal-central scalp sites that occurs after error
commission. The relationship between the ERN and broader
patterns of brain activity measured across the entire scalp
that support error processing during early childhood is
unclear. We examined the relationship between the ERN and
EEG microstates - whole-brain patterns of dynamically
evolving scalp potential topographies that reflect periods
of synchronized neural activity - during both a go/no-go
task and resting-state in 90, 4-8-year-old children. The
mean amplitude of the ERN was quantified during the -64 to
108 millisecond (ms) period of time relative to error
commission, which was determined by data-driven microstate
segmentation of error-related activity. We found that
greater magnitude of the ERN associated with greater global
explained variance (GEV; i.e., the percentage of total
variance in the data explained by a given microstate) of an
error-related microstate observed during the same -64 to 108
ms period (i.e., error-related microstate 3), and to greater
anxiety risk as measured by parent-reported behavioral
inhibition. During resting-state, six data-driven
microstates were identified. Both greater magnitude of the
ERN and greater GEV values of error-related microstate 3
associated with greater GEV values of resting-state
microstate 4, which showed a frontal-central scalp
topography. Source localization results revealed overlap
between the underlying neural generators of error-related
microstate 3 and resting-state microstate 4 and canonical
brain networks (e.g., ventral attention) known to support
the higher-order cognitive processes involved in error
processing. Taken together, our results clarify how
individual differences in error-related and intrinsic brain
activity are related and enhance our understanding of
developing brain network function and organization
supporting error processing during early
childhood.},
Doi = {10.1007/s10548-023-01030-2},
Key = {fds374968}
}
%% Bellaiche, Lucas
@article{fds374172,
Author = {Bellaiche, L and Shahi, R and Turpin, MH and Ragnhildstveit, A and Sprockett, S and Barr, N and Christensen, A and Seli,
P},
Title = {Humans versus AI: whether and why we prefer human-created
compared to AI-created artwork.},
Journal = {Cognitive research: principles and implications},
Volume = {8},
Number = {1},
Pages = {42},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1186/s41235-023-00499-6},
Abstract = {With the recent proliferation of advanced artificial
intelligence (AI) models capable of mimicking human
artworks, AI creations might soon replace products of human
creativity, although skeptics argue that this outcome is
unlikely. One possible reason this may be unlikely is that,
independent of the physical properties of art, we place
great value on the imbuement of the human experience in art.
An interesting question, then, is whether and why people
might prefer human-compared to AI-created artworks. To
explore these questions, we manipulated the purported
creator of pieces of art by randomly assigning a
"Human-created" or "AI-created" label to paintings actually
created by AI, and then assessed participants' judgements of
the artworks across four rating criteria (Liking, Beauty,
Profundity, and Worth). Study 1 found increased positive
judgements for human- compared to AI-labelled art across
all criteria. Study 2 aimed to replicate and extend Study 1
with additional ratings (Emotion, Story, Meaningful, Effort,
and Time to create) intended to elucidate why people
more-positively appraise Human-labelled artworks. The main
findings from Study 1 were replicated, with narrativity
(Story) and perceived effort behind artworks (Effort)
moderating the label effects ("Human-created" vs.
"AI-created"), but only for the sensory-level judgements
(Liking, Beauty). Positive personal attitudes toward
AI moderated label effects for more-communicative
judgements (Profundity, Worth). These studies demonstrate
that people tend to be negatively biased against AI-created
artworks relative to purportedly human-created artwork, and
suggest that knowledge of human engagement in the artistic
process contributes positively to appraisals of
art.},
Doi = {10.1186/s41235-023-00499-6},
Key = {fds374172}
}
@article{fds372230,
Author = {Bellaiche, L and Smith, AP and Barr, N and Christensen, A and Williams,
C and Ragnhildstveit, A and Schooler, J and Beaty, R and Chatterjee, A and Seli, P},
Title = {Back to the basics: Abstract painting as an index of
creativity},
Journal = {Creativity Research Journal},
Volume = {35},
Number = {4},
Pages = {698-713},
Publisher = {Informa UK Limited},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/10400419.2023.2243100},
Abstract = {Researchers have invested a great deal in creating reliable,
“gold-standard” creativity assessments that can be
administered in controlled laboratory settings, though these
efforts have come at the cost of not using ecologically and
face-valid tasks. To help fill this critical gap, we
developed and implemented a novel, face-valid paradigm that
required participants to paint abstract pieces of art, which
were later rated for creative quality. We first sought to
evaluate whether there was good convergence among creativity
ratings provided by independent raters. Next, we examined
whether its measure of creativity correlated with (a)
existing creativity measures and (b) individual traits (e.g.
openness, fluid intelligence) that are typically correlated
with indices of creativity. Our findings indicate that our
abstract-painting paradigm is feasible to implement
(independent ratings of the creativity of the paintings
converged well), and that its measure of creativity
significantly correlated with some of the gold-standard
indices of creativity (thereby providing convergent
validity). These findings suggest that having participants
engage in abstract painting provides a valid index of
creativity, thereby opening new opportunities for future
research to index a more-face-valid measure of
creativity.},
Doi = {10.1080/10400419.2023.2243100},
Key = {fds372230}
}
%% Bennett, Gary G.
@article{fds370933,
Author = {Ruiz, JM and Bacon, SL and Bennett, GG and Brondolo, E and Czajkowski,
SM and Davidson, KW and Epel, ES and Revenson, TA and Behavioral
Medicine Research Council},
Title = {Behavioral Medicine Research Council (BMRC) Statement
Papers: A New Approach to Consensus Building in Behavioral
Medicine Science.},
Journal = {Psychosomatic medicine},
Volume = {85},
Number = {4},
Pages = {296-297},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1097/psy.0000000000001185},
Doi = {10.1097/psy.0000000000001185},
Key = {fds370933}
}
@article{fds370371,
Author = {Berger, MB and Chisholm, M and Miller, HN and Askew, S and Kay, MC and Bennett, GG},
Title = {"We bleed for our community:" A qualitative exploration of
the implementation of a pragmatic weight gain prevention
trial from the perspectives of community health center
professionals.},
Journal = {BMC Public Health},
Volume = {23},
Number = {1},
Pages = {695},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1186/s12889-023-15574-2},
Abstract = {BACKGROUND: Clinical trial implementation continues to shift
toward pragmatic design, with the goal of increasing future
adoption in clinical practice. Yet, few pragmatic trials
within clinical settings have qualitatively assessed
stakeholder input, especially from those most impacted by
research implementation and outcomes, i.e., providers and
staff. Within this context, we conducted a qualitative study
of the implementation of a pragmatic digital health obesity
trial with employees at a Federally qualified health center
(FQHC) network in central North Carolina. METHODS:
Participant recruitment was conducted through purposive
sampling of FQHC employees from a variety of backgrounds.
Two researchers conducted semi-structured qualitative
interviews and collected demographic data. Interviews were
digitally recorded, professionally transcribed and
double-coded by two independent researchers using NVivo 12.
Coding discrepancies were reviewed by a third researcher
until intercoder consensus was reached. Responses were
compared within and across participants to elucidate
emergent themes. RESULTS: Eighteen qualitative interviews
were conducted, of whom 39% provided direct medical care to
patients and 44% worked at the FQHC for at least seven
years. Results illuminated the challenges and successes of a
pragmatically designed obesity treatment intervention within
the community that serves medically vulnerable patients.
Although limited time and staffing shortages may have
challenged recruitment processes, respondents described
early buy-in from leadership; an alignment of organizational
and research goals; and consideration of patient needs as
facilitators to implementation. Respondents also described
the need for personnel power to sustain novel research
interventions and considerations of health center resource
constraints. CONCLUSIONS: Results from this study contribute
to the limited literature on pragmatic trials utilizing
qualitative methods, particularly in community-based obesity
treatment. To continue to merge the gaps between research
implementation and clinical care, qualitative assessments
that solicit stakeholder input are needed within pragmatic
trial design. For maximum impact, researchers may wish to
solicit input from a variety of professionals at trial onset
and ensure that shared common goals and open collaboration
between all partners is maintained throughout the trial.
TRIAL REGISTRATION: This trial was registered with
ClinicalTrials.gov (NCT03003403) on December 28,
2016.},
Doi = {10.1186/s12889-023-15574-2},
Key = {fds370371}
}
@article{fds370717,
Author = {Ruiz, JM and Bacon, SL and Bennett, GG and Brondolo, E and Czajkowski,
SM and Davidson, KW and Epel, ES and Revenson, TA},
Title = {Behavioral Medicine Research Council (BMRC) Statement
Papers: A New Approach to Consensus Building in Behavioral
Medicine Science.},
Journal = {Annals of behavioral medicine : a publication of the Society
of Behavioral Medicine},
Volume = {57},
Number = {5},
Pages = {355-356},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1093/abm/kaac038},
Doi = {10.1093/abm/kaac038},
Key = {fds370717}
}
@article{fds369356,
Author = {Kay, MC and Hammad, NM and Truong, T and Herring, SJ and Bennett,
GG},
Title = {Feasibility, Acceptability, and Initial Efficacy of a
Digital Intervention to Improve Consumption of Foods
Received within a National Nutrition Assistance
Program.},
Journal = {Nutrients},
Volume = {15},
Number = {2},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.3390/nu15020438},
Abstract = {Many mothers are vulnerable to poor diet quality,
particularly those living in low-income households. The
Special Supplemental Nutrition Program for Women, Infants,
and Children (WIC) provides nutrient-rich foods through its
benefits packages, but many WIC participants are not
redeeming them. We assessed the feasibility and
acceptability of a digital intervention to support
redemption and consumption of WIC-approved foods to
ultimately improve diet quality. We enrolled 54
maternal-child dyads receiving WIC benefits to receive three
to four weekly text messages for 12 weeks focused on
behavioral goals to improve consumption of WIC-approved
foods. We assessed engagement with weekly tracking messages
and satisfaction and collected 24 h dietary recalls to
assess preliminary efficacy on dietary intake. Participants
were mostly non-Hispanic white (63%) and working (63%), and
responded to 7.4 (standard deviation: 4.6) of the 12 weekly
messages. Half (n = 27) were high engagers (responded to 80%
or more of weekly messages), with 28% (n = 15) responding to
all messages. Most felt the feedback (94%) and tips (87%)
were helpful and would recommend the program (91%). More
were consuming leafy green vegetables compared to baseline
(p = 0.01). Mothers of children enrolled in WIC found a text
messaging intervention focused on consumption of
WIC-approved foods enjoyable and helpful.},
Doi = {10.3390/nu15020438},
Key = {fds369356}
}
@article{fds364179,
Author = {Tyson, CC and Svetkey, LP and Lin, P-H and Granados, I and Kennedy, D and Dunbar, KT and Redd, C and Bennett, G and Boulware, LE and Fish,
LJ},
Title = {Self-Perceived Barriers and Facilitators to Dietary
Approaches to Stop Hypertension Diet Adherence Among Black
Americans With Chronic Kidney Disease: A Qualitative
Study.},
Journal = {J Ren Nutr},
Volume = {33},
Number = {1},
Pages = {59-68},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1053/j.jrn.2022.05.002},
Abstract = {OBJECTIVE: The Dietary Approaches to Stop Hypertension
(DASH) eating plan improves hypertension in Black
individuals and is associated with favorable chronic kidney
disease (CKD) outcomes. Yet, adherence to DASH is low among
US adults in general, particularly among Black Americans. We
assessed perceptions about DASH, its cultural compatibility,
and barriers and facilitators to DASH adherence in Black
adults with CKD. DESIGN AND METHODS: We conducted focus
groups and semistructured individual interviews involving 22
Black men and women with CKD Stages 3-4 from outpatient
clinics at a US academic medical center. Transcripts of
audio-recorded interviews were analyzed using thematic
analysis. RESULTS: Among participants (2 focus groups
[N = 8 and 5] and 9 individual interviews), 13 (59%) had
CKD Stage 3, 13 (59%) were female, the median age was
61 years, and 19 (90%) had hypertension. After receiving
information about DASH, participants perceived it as
culturally compatible based on 3 emergent themes: (1) Black
individuals already eat DASH-recommended foods ("Blacks eat
pretty much like this"), (2) traditional recipes (e.g.,
southern or soul food) can be modified into healthy versions
("you can come up with decent substitutes to make it just as
good"), and ( 3) diet is not uniform among Black individuals
("I can't say that I eat traditional"). Perceived barriers
to DASH adherence included unfamiliarity with serving sizes,
poor cooking skills, unsupportive household members, and
high cost of healthy food. Eleven (52%) reported after
paying monthly bills that they "rarely" or "never" had
leftover money to purchase healthy food. Perceived
facilitators included having local access to healthy food,
living alone or with supportive household members, and
having willpower and internal/external motivation for
change. CONCLUSIONS: Black adults with CKD viewed DASH as a
healthy, culturally compatible diet. Recognizing that diet
in Black adults is not uniform, interventions should
emphasize person-centered, rather than stereotypically
culture-centered, approaches to DASH adherence.},
Doi = {10.1053/j.jrn.2022.05.002},
Key = {fds364179}
}
@article{fds367657,
Author = {Miller, HN and Berger, MB and Askew, S and Kay, MC and Chisholm, M and Sirdeshmukh, G and Hopkins, CM and Brewer, A and DeVries, A and Holder,
M and Bennett, GG},
Title = {Recruitment of diverse community health center patients in a
pragmatic weight gain prevention trial.},
Journal = {J Clin Transl Sci},
Volume = {7},
Number = {1},
Pages = {e22},
Year = {2023},
url = {http://dx.doi.org/10.1017/cts.2022.475},
Abstract = {INTRODUCTION: Pragmatic trials are needed to establish
evidence-based obesity treatment in primary care settings,
particularly in community health centers (CHCs) that serve
populations at heightened risk of obesity. Recruiting a
representative trial sample is a critical first step to
informing care for diverse communities. We described
recruitment strategies utilized in a pragmatic obesity trial
and assessed the sociodemographic characteristics and odds
of enrollment by recruitment strategy. METHODS: We analyzed
data from Balance, a pragmatic trial implemented within a
network of CHCs. We recruited participants via health
center-based and electronic health record (EHR)-informed
mail recruitment. We analyzed associations between
sociodemographic characteristics and the return rate of
patient authorization forms (required for participation)
from EHR-informed mail recruitment. We also compared
sociodemographic characteristics and randomization odds by
recruitment strategy after returning authorization forms.
RESULTS: Of the individuals recruited through EHR-informed
mail recruitment, females were more likely than males to
return authorization forms; however, there were no
differences in rates of return by preferred language
(English/Spanish) or age. Females; underrepresented racial
and ethnic groups; Spanish speakers; younger adults; and
those with lower education levels were recruited more
successfully in the health center. In contrast, their
counterparts were more responsive to mail recruitment. Once
authorization forms were returned, the odds of being
randomized did not significantly differ by recruitment
method. CONCLUSION: Health center-based recruitment was
essential to meeting recruitment targets in a pragmatic
weight gain prevention trial, specifically for Hispanic and
Spanish-speaking communities. Future pragmatic trials should
consider leveraging in-person recruitment for
underrepresented groups in research.},
Doi = {10.1017/cts.2022.475},
Key = {fds367657}
}
%% Bergelson, Elika
@article{fds376037,
Author = {Moore, C and Bergelson, E},
Title = {Wordform variability in infants' language environment and
its effects on early word learning.},
Journal = {Cognition},
Volume = {245},
Pages = {105694},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1016/j.cognition.2023.105694},
Abstract = {Most research regarding early word learning in English tends
to make the simplifying assumption that there exists a
one-to-one mapping between concrete objects and their
labels. In the current work, we provide evidence that runs
counter to this assumption, aligning English with more
morphologically-rich languages. We suggest that even in a
morphologically-poor language like English, real world
language input to infants does not provide tidy 1-to-1
mappings. Instead, infants encounter many variant wordforms
for familiar nouns (e.g. dog∼doggy∼dogs). We explore
this wordform variability in 44 English-learning infants'
naturalistic environments using a longitudinal corpus of
infant-available speech. We look at both the frequency and
composition of wordform variability. We find two broad
categories of variability: referent-changing alterations,
where words were pluralized or compounded (e.g.
coat∼raincoats); and wordplay, where words changed form
without a notable change in referent (e.g. bird∼birdie).
We further find that wordplay occurs with a limited number
of lemmas that are usually early-learned, high-frequency,
and shorter. When looking at all wordform variability, we
find that individual words with higher levels of wordform
variability are learned earlier than words with fewer
wordforms, over and above the effect of frequency.},
Doi = {10.1016/j.cognition.2023.105694},
Key = {fds376037}
}
@article{fds375235,
Author = {Laing, C and Bergelson, E},
Title = {Analyzing the effect of sibling number on input and output
in the first 18 months.},
Journal = {Infancy : the official journal of the International Society
on Infant Studies},
Volume = {29},
Number = {2},
Pages = {175-195},
Publisher = {WILEY},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1111/infa.12578},
Abstract = {Prior research suggests that across a wide range of
cognitive, educational, and health-based measures,
first-born children outperform their later-born peers.
Expanding on this literature using naturalistic
home-recorded data and parental vocabulary reports, we find
that early language outcomes vary by number of siblings in a
sample of 43 English-learning U.S. children from mid-to-high
socioeconomic status homes. More specifically, we find that
children in our sample with two or more-but not one-older
siblings had smaller productive vocabularies at 18 months,
and heard less input from caregivers across several measures
than their peers with less than two siblings. We discuss
implications regarding what infants experience and learn
across a range of family sizes in infancy.},
Doi = {10.1111/infa.12578},
Key = {fds375235}
}
@article{fds375505,
Author = {Campbell, E and Casillas, R and Bergelson, E},
Title = {The role of vision in the acquisition of words: Vocabulary
development in blind toddlers.},
Journal = {Developmental science},
Pages = {e13475},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1111/desc.13475},
Abstract = {What is vision's role in driving early word production? To
answer this, we assessed parent-report vocabulary
questionnaires administered to congenitally blind children
(N = 40, Mean age = 24 months [R: 7-57 months]) and
compared the size and contents of their productive
vocabulary to those of a large normative sample of sighted
children (N = 6574). We found that on average, blind
children showed a roughly half-year vocabulary delay
relative to sighted children, amid considerable variability.
However, the content of blind and sighted children's
vocabulary was statistically indistinguishable in word
length, part of speech, semantic category, concreteness,
interactiveness, and perceptual modality. At a finer-grained
level, we also found that words' perceptual properties
intersect with children's perceptual abilities. Our findings
suggest that while an absence of visual input may initially
make vocabulary development more difficult, the content of
the early productive vocabulary is largely resilient to
differences in perceptual access. RESEARCH HIGHLIGHTS:
Infants and toddlers born blind (with no other diagnoses)
show a 7.5 month productive vocabulary delay on average,
with wide variability. Across the studied age range
(7-57 months), vocabulary delays widened with age. Blind
and sighted children's early vocabularies contain similar
distributions of word lengths, parts of speech, semantic
categories, and perceptual modalities. Blind children (but
not sighted children) were more likely to say visual words
which could also be experienced through other
senses.},
Doi = {10.1111/desc.13475},
Key = {fds375505}
}
@article{fds373687,
Author = {Meylan, SC and Foushee, R and Wong, NH and Bergelson, E and Levy,
RP},
Title = {How adults understand what young children
say.},
Journal = {Nature human behaviour},
Volume = {7},
Number = {12},
Pages = {2111-2125},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1038/s41562-023-01698-3},
Abstract = {Children's early speech often bears little resemblance to
that of adults, and yet parents and other caregivers are
able to interpret that speech and react accordingly. Here we
investigate how adult listeners' inferences reflect
sophisticated beliefs about what children are trying to
communicate, as well as how children are likely to pronounce
words. Using a Bayesian framework for modelling spoken word
recognition, we find that computational models can replicate
adult interpretations of children's speech only when they
include strong, context-specific prior expectations about
the messages that children will want to communicate. This
points to a critical role of adult cognitive processes in
supporting early communication and reveals how children can
actively prompt adults to take actions on their behalf even
when they have only a nascent understanding of the adult
language. We discuss the wide-ranging implications of the
powerful listening capabilities of adults for theories of
first language acquisition.},
Doi = {10.1038/s41562-023-01698-3},
Key = {fds373687}
}
@article{fds374572,
Author = {Bergelson, E and Soderstrom, M and Schwarz, I-C and Rowland, CF and Ramírez-Esparza, N and R Hamrick and L and Marklund, E and Kalashnikova, M and Guez, A and Casillas, M and Benetti, L and Alphen,
PV and Cristia, A},
Title = {Everyday language input and production in 1,001 children
from six continents.},
Journal = {Proceedings of the National Academy of Sciences of the
United States of America},
Volume = {120},
Number = {52},
Pages = {e2300671120},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1073/pnas.2300671120},
Abstract = {Language is a universal human ability, acquired readily by
young children, who otherwise struggle with many basics of
survival. And yet, language ability is variable across
individuals. Naturalistic and experimental observations
suggest that children's linguistic skills vary with factors
like socioeconomic status and children's gender. But which
factors really influence children's day-to-day language use?
Here, we leverage speech technology in a big-data approach
to report on a unique cross-cultural and diverse data set:
>2,500 d-long, child-centered audio-recordings of 1,001 2-
to 48-mo-olds from 12 countries spanning six continents
across urban, farmer-forager, and subsistence-farming
contexts. As expected, age and language-relevant clinical
risks and diagnoses predicted how much speech (and
speech-like vocalization) children produced. Critically, so
too did adult talk in children's environments: Children who
heard more talk from adults produced more speech. In
contrast to previous conclusions based on more limited
sampling methods and a different set of language proxies,
socioeconomic status (operationalized as maternal education)
was not significantly associated with children's productions
over the first 4 y of life, and neither were gender or
multilingualism. These findings from large-scale
naturalistic data advance our understanding of which factors
are robust predictors of variability in the speech behaviors
of young learners in a wide range of everyday
contexts.},
Doi = {10.1073/pnas.2300671120},
Key = {fds374572}
}
@article{fds370372,
Author = {Liu, J and Hilton, CB and Bergelson, E and Mehr, SA},
Title = {Language experience predicts music processing in a
half-million speakers of fifty-four languages.},
Journal = {Current biology : CB},
Volume = {33},
Number = {10},
Pages = {1916-1925.e4},
Publisher = {Elsevier BV},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1016/j.cub.2023.03.067},
Abstract = {Tonal languages differ from other languages in their use of
pitch (tones) to distinguish words. Lifelong experience
speaking and hearing tonal languages has been argued to
shape auditory processing in ways that generalize beyond the
perception of linguistic pitch to the perception of pitch in
other domains like music. We conducted a meta-analysis of
prior studies testing this idea, finding moderate evidence
supporting it. But prior studies were limited by mostly
small sample sizes representing a small number of languages
and countries, making it challenging to disentangle the
effects of linguistic experience from variability in music
training, cultural differences, and other potential
confounds. To address these issues, we used web-based
citizen science to assess music perception skill on a global
scale in 34,034 native speakers of 19 tonal languages (e.g.,
Mandarin, Yoruba). We compared their performance to 459,066
native speakers of other languages, including 6
pitch-accented (e.g., Japanese) and 29 non-tonal languages
(e.g., Hungarian). Whether or not participants had taken
music lessons, native speakers of all 19 tonal languages had
an improved ability to discriminate musical melodies on
average, relative to speakers of non-tonal languages. But
this improvement came with a trade-off: tonal language
speakers were also worse at processing the musical beat. The
results, which held across native speakers of many diverse
languages and were robust to geographic and demographic
variation, demonstrate that linguistic experience shapes
music perception, with implications for relations between
music, language, and culture in the human
mind.},
Doi = {10.1016/j.cub.2023.03.067},
Key = {fds370372}
}
@article{fds367924,
Author = {Bulgarelli, F and Bergelson, E},
Title = {Talker variability is not always the right noise: 14 month
olds struggle to learn dissimilar word-object pairs under
talker variability conditions.},
Journal = {Journal of experimental child psychology},
Volume = {227},
Pages = {105575},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1016/j.jecp.2022.105575},
Abstract = {Seminal work by Stager & Werker (1997) finds that
14-month-olds can rapidly learn two word-object pairings if
the words are distinct (e.g. "neem" and "lif") but not
similar (e.g. the minimal pair "bih" and "dih"). More
recently, studies have found that adding talker variability
during exposure to new word-object pairs lets 14-month-olds
succeed on the more challenging minimal pair task,
presumably due to talker variability highlighting the
"relevant" consistencies between the similar words (Rost &
McMurray, 2009; Galle et al., 2015; Hohle et al., 2020). It
remains an open question, however, whether talker
variability would be similarly useful for learning new
word-object pairings when the words themselves are already
distinct, or whether instead this extra variability may
extinguish learning due to increased task demands. We find
evidence for the latter. Namely, in our sample of 54
English-learning 14-month-olds, training infants on two
word-object pairings (e.g. "neem" with a dog toy and "lof"
with a kitchen tool) only led them to notice when the words
and objects were switched if they were trained with
single-speaker identical word tokens. When the training
featured talker variability (from one or multiple talkers)
infants failed to learn the pairings. We suggest that when
talker variability is not necessary to highlight the
invariant differences between similar words, it may actually
increase task difficulty, making it harder for infants to
determine what to attend to in the earliest phases of word
learning.},
Doi = {10.1016/j.jecp.2022.105575},
Key = {fds367924}
}
@article{fds376090,
Author = {Lavechin, M and Metais, M and Titeux, H and Boissonnet, A and Copet, J and Riviere, M and Bergelson, E and Cristia, A and Dupoux, E and Bredin,
H},
Title = {Brouhaha: Multi-Task Training for Voice Activity Detection,
Speech-to-Noise Ratio, and C50 Room Acoustics
Estimation},
Journal = {2023 IEEE Automatic Speech Recognition and Understanding
Workshop, ASRU 2023},
Year = {2023},
Month = {January},
ISBN = {9798350306897},
url = {http://dx.doi.org/10.1109/ASRU57964.2023.10389718},
Abstract = {Most automatic speech processing systems register degraded
performance when applied to noisy or reverberant speech. But
how can one tell whether speech is noisy or reverberant? We
propose Brouhaha, a neural network jointly trained to
extract speech/non-speech segments, speech-to-noise ratios,
and C50 room acoustics from single-channel recordings.
Brouhaha is trained using a data-driven approach in which
noisy and reverberant audio segments are synthesized. We
first evaluate its performance and demonstrate that the
proposed multi-task regime is beneficial. We then present
two scenarios illustrating how Brouhaha can be used on
naturally noisy and reverberant data: 1) to investigate the
errors made by a speaker diarization model (pyannote.audio);
and 2) to assess the reliability of an automatic speech
recognition model (Whisper from OpenAI). Both our pipeline
and a pretrained model are open source and shared with the
speech community.},
Doi = {10.1109/ASRU57964.2023.10389718},
Key = {fds376090}
}
%% Bettman, James R.
@article{fds369095,
Author = {Brick, DJ and Wight, KG and Bettman, JR and Chartrand, TL and Fitzsimons, GJ},
Title = {Celebrate Good Times: How Celebrations Increase Perceived
Social Support},
Journal = {Journal of Public Policy and Marketing},
Volume = {42},
Number = {2},
Pages = {115-132},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1177/07439156221145696},
Abstract = {Despite the ubiquity of celebrations in everyday life,
little is known about how celebrations may contribute to
consumer well-being. In the current work, the authors
propose that celebrations promote perceived social support,
which prior work has conceptualized as the belief that
others will be there for you for future negative life
events. The authors further theorize that celebrations
require three key characteristics that, in combination, are
necessary for increasing perceived social support.
Specifically, celebrations must (1) mark an individual's
separate positive event and (2) involve consumption (3) with
others (i.e., social). They test this theory across eight
studies and demonstrate a process mechanism for this effect:
these characteristics lead to increases in enacted support
and perceived responsiveness, which in turn lead to
increases in more general perceived social support. They
then extend these findings by investigating virtually held
celebrations, the individual's role at the celebration, and
a downstream prosocial outcome. By doing so, this work
highlights the broader benefits of celebrations beyond the
focal individual and the immediate experience. Finally,
specific policy implications and suggestions for enhancing
consumer well-being are provided.},
Doi = {10.1177/07439156221145696},
Key = {fds369095}
}
@article{fds372840,
Author = {Wiener, HJD and Bettman, JR and Luce, MF},
Title = {Product-facilitated conversations: When does starting a
conversation by mentioning a product lead to better
conversational outcomes?},
Journal = {Journal of Consumer Psychology},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1002/jcpy.1387},
Abstract = {This paper examines product-facilitated conversations. In
three studies, we show that the products consumers publicly
display influence how other consumers start conversations
with them and how enjoyable and self-disclosing these
conversations are. Study 1 is an experiment in the field
that shows that product-facilitated conversations are deeper
and more enjoyable than non-product-facilitated ones. Study
2 examines the characteristics of products that, when
mentioned, lead to good conversations and identifies
uniqueness and commonality as key characteristics. Study 3
is an additional experiment in the field that tests these
characteristics and shows that products with those
characteristics are better conversation starters than the
weather. Overall, these studies show novel social benefits
to talking about products and generate new ideas about how
talking about products can help consumers meet new people,
smooth awkward social situations, and build
relationships.},
Doi = {10.1002/jcpy.1387},
Key = {fds372840}
}
%% Bilbo, Staci D.
@article{fds374234,
Author = {Bordt, EA and Moya, HA and Jo, YC and Ravichandran, CT and Bankowski,
IM and Ceasrine, AM and McDougle, CJ and Carlezon, WA and Bilbo,
SD},
Title = {Gonadal hormones impart male-biased behavioral
vulnerabilities to immune activation via microglial
mitochondrial function.},
Journal = {Brain, behavior, and immunity},
Volume = {115},
Pages = {680-695},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.bbi.2023.11.010},
Abstract = {There is a strong male bias in the prevalence of many
neurodevelopmental disorders such as autism spectrum
disorder. However, the mechanisms underlying this sex bias
remain elusive. Infection during the perinatal period is
associated with an increased risk of neurodevelopmental
disorder development. Here, we used a mouse model of
early-life immune activation that reliably induces deficits
in social behaviors only in males. We demonstrate that
male-biased alterations in social behavior are dependent
upon microglial immune signaling and are coupled to
alterations in mitochondrial morphology, gene expression,
and function specifically within microglia, the innate
immune cells of the brain. Additionally, we show that this
behavioral and microglial mitochondrial vulnerability to
early-life immune activation is programmed by the
male-typical perinatal gonadal hormone surge. These findings
demonstrate that social behavior in males over the lifespan
are regulated by microglia-specific mechanisms that are
shaped by events that occur in early development.},
Doi = {10.1016/j.bbi.2023.11.010},
Key = {fds374234}
}
@article{fds370885,
Author = {Smith, CJ and Rendina, DN and Kingsbury, MA and Malacon, KE and Nguyen,
DM and Tran, JJ and Devlin, BA and Raju, RM and Clark, MJ and Burgett, L and Zhang, JH and Cetinbas, M and Sadreyev, RI and Chen, K and Iyer, MS and Bilbo, SD},
Title = {Microbial modulation via cross-fostering prevents the
effects of pervasive environmental stressors on microglia
and social behavior, but not the dopamine
system.},
Journal = {Molecular psychiatry},
Volume = {28},
Number = {6},
Pages = {2549-2562},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1038/s41380-023-02108-w},
Abstract = {Environmental toxicant exposure, including air pollution, is
increasing worldwide. However, toxicant exposures are not
equitably distributed. Rather, low-income and minority
communities bear the greatest burden, along with higher
levels of psychosocial stress. Both air pollution and
maternal stress during pregnancy have been linked to
neurodevelopmental disorders such as autism, but biological
mechanisms and targets for therapeutic intervention remain
poorly understood. We demonstrate that combined prenatal
exposure to air pollution (diesel exhaust particles, DEP)
and maternal stress (MS) in mice induces social behavior
deficits only in male offspring, in line with the male bias
in autism. These behavioral deficits are accompanied by
changes in microglial morphology and gene expression as well
as decreased dopamine receptor expression and dopaminergic
fiber input in the nucleus accumbens (NAc). Importantly, the
gut-brain axis has been implicated in ASD, and both
microglia and the dopamine system are sensitive to the
composition of the gut microbiome. In line with this, we
find that the composition of the gut microbiome and the
structure of the intestinal epithelium are significantly
shifted in DEP/MS-exposed males. Excitingly, both the
DEP/MS-induced social deficits and microglial alterations in
males are prevented by shifting the gut microbiome at birth
via a cross-fostering procedure. However, while social
deficits in DEP/MS males can be reversed by chemogenetic
activation of dopamine neurons in the ventral tegmental
area, modulation of the gut microbiome does not impact
dopamine endpoints. These findings demonstrate male-specific
changes in the gut-brain axis following DEP/MS and suggest
that the gut microbiome is an important modulator of both
social behavior and microglia.},
Doi = {10.1038/s41380-023-02108-w},
Key = {fds370885}
}
@article{fds369662,
Author = {Bilbo, S and Smith, C and Rendina, D and Kingsbury, M and Malacon, K and Nguyen, D and Tran, J and Devlin, B and Raju, R and Clark, M and Burgett,
L and Zhang, J and Cetinbas, M and Sadreyev, R and Chen, K and Iyer,
M},
Title = {Microbial modulation prevents the effects of pervasive
environmental stressors on microglia and social behavior,
but not the dopamine system.},
Journal = {Res Sq},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.21203/rs.3.rs-2548369/v1},
Abstract = {Environmental toxicant exposure, including air pollution, is
increasing worldwide. However, toxicant exposures are not
equitably distributed. Rather, low-income and minority
communities bear the greatest burden, along with higher
levels of psychosocial stress. Both air pollution and
maternal stress during pregnancy have been linked to
neurodevelopmental disorders such as autism, but biological
mechanisms and targets for therapeutic intervention remain
poorly understood. We demonstrate that combined prenatal
exposure to air pollution (diesel exhaust particles, DEP)
and maternal stress (MS) in mice induces social behavior
deficits only in male offspring, in line with the male bias
in autism. These behavioral deficits are accompanied by
changes in microglial morphology and gene expression as well
as decreased dopamine receptor expression and dopaminergic
fiber input in the nucleus accumbens (NAc). Importantly, the
gut-brain axis has been implicated in ASD, and both
microglia and the dopamine system are sensitive to the
composition of the gut microbiome. In line with this, we
find that the composition of the gut microbiome and the
structure of the intestinal epithelium are significantly
shifted in DEP/MS-exposed males. Excitingly, both the
DEP/MS-induced social deficits and microglial alterations in
males are prevented by shifting the gut microbiome at birth
via a cross-fostering procedure. However, while social
deficits in DEP/MS males can be reversed by chemogenetic
activation of dopamine neurons in the ventral tegmental
area, modulation of the gut microbiome does not impact
dopamine endpoints. These findings demonstrate male-specific
changes in the gut-brain axis following DEP/MS and suggest
that the gut microbiome is an important modulator of both
social behavior and microglia.},
Doi = {10.21203/rs.3.rs-2548369/v1},
Key = {fds369662}
}
%% Blumenthal, James A.
@article{fds374579,
Author = {Hughes, GC and Chen, EP and Browndyke, JN and Szeto, WY and DiMaio, JM and Brinkman, WT and Gaca, JG and Blumenthal, JA and Karhausen, JA and Bisanar, T and James, ML and Yanez, D and Li, Y-J and Mathew,
JP},
Title = {Cognitive Effects of Body Temperature During Hypothermic
Circulatory Arrest Trial (GOT ICE): A Randomized Clinical
Trial Comparing Outcomes After Aortic Arch
Surgery.},
Journal = {Circulation},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1161/CIRCULATIONAHA.123.067022},
Abstract = {BACKGROUND: Deep hypothermia has been the standard for
hypothermic circulatory arrest (HCA) during aortic arch
surgery. However, centers worldwide have shifted toward
lesser hypothermia with antegrade cerebral perfusion. This
has been supported by retrospective data, but there has yet
to be a multicenter, prospective randomized study comparing
deep versus moderate hypothermia during HCA. METHODS: This
was a randomized single-blind trial (GOT ICE) of patients
undergoing arch surgery with HCA plus antegrade cerebral
perfusion at 4 US referral aortic centers (August
2016-December 2021). Patients were randomized to 1 of 3
hypothermia groups: DP, deep (≤20.0 °C); LM,
low-moderate (20.1-24.0 °C); and HM, high-moderate
(24.1-28.0 °C). The primary outcome was composite global
cognitive change score between baseline and 4 weeks
postoperatively. Intention-to-treat analysis to evaluate if:
(1) LM noninferior to DP on global cognitive change score;
(2) DP superior to HM. The secondary outcomes were
domain-specific cognitive change scores, neuroimaging
findings, quality of life, and adverse events. RESULTS: A
total of 308 patients consented; 282 met inclusion and were
randomized. A total of 273 completed surgery, and 251
completed the 4-week follow-up (DP, 85 [34%]; LM, 80 [34%];
HM, 86 [34%]). Mean global cognitive change score from
baseline to 4 weeks in the LM group was noninferior to the
DP group; likewise, no significant difference was observed
between DP and HM. Noninferiority of LM versus DP, and lack
of difference between DP and HM, remained for
domain-specific cognitive change scores, except structured
verbal memory, with noninferiority of LM versus DP not
established and structured verbal memory better preserved in
DP versus HM (P = 0.036). There were no significant
differences in structural or functional magnetic resonance
imaging brain imaging between groups postoperatively.
Regardless of temperature, patients who underwent HCA
demonstrated significant reductions in cerebral gray matter
volume, cortical thickness, and regional brain functional
connectivity. Thirty-day in-hospital mortality, major
morbidity, and quality of life were not different between
groups. CONCLUSIONS: This randomized multicenter study
evaluating arch surgery HCA temperature strategies found
low-moderate hypothermia noninferior to traditional deep
hypothermia on global cognitive change 4 weeks after
surgery, although in secondary analysis, structured verbal
memory was better preserved in the deep group. The verbal
memory differences in the low- and high-moderate groups and
structural and functional connectivity reductions from
baseline merit further investigation and suggest
opportunities to further optimize brain perfusion during
HCA. REGISTRATION: URL: https://www.clinicaltrials.gov;
Unique identifier: NCT02834065.},
Doi = {10.1161/CIRCULATIONAHA.123.067022},
Key = {fds374579}
}
@article{fds371880,
Author = {Ribeiro, F and Teixeira, M and Alves, AJ and Sherwood, A and Blumenthal,
JA},
Title = {Lifestyle Medicine as a Treatment for Resistant
Hypertension.},
Journal = {Curr Hypertens Rep},
Volume = {25},
Number = {10},
Pages = {313-328},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1007/s11906-023-01253-5},
Abstract = {PURPOSE OF REVIEW: Approximately 10% of the adults with
hypertension fail to achieve the recommended blood
pressure treatment targets on 3 antihypertensive medications
or require ≥ 4 medications to achieve goal. These
patients with 'resistant hypertension' have an increased
risk of target organ damage, adverse clinical events, and
all-cause mortality. Although lifestyle modification is
widely recommended as a first-line approach for the
management of high blood pressure, the effects of lifestyle
modifications in patients with resistant hypertension has
not been widely studied. This review aims to provide an
overview of the emerging evidence on the benefits of
lifestyle modifications in patients with resistant
hypertension, reviews potential mechanisms by which
lifestyles may reduce blood pressure, and discusses the
clinical implications of the recent findings in this field.
RECENT FINDINGS: Evidence from single-component randomized
clinical trials demonstrated that aerobic exercise, weight
loss and dietary modification can reduce clinic and
ambulatory blood pressure in patients with resistant
hypertension. Moreover, evidence from multi-component trials
involving exercise and dietary modification and weight
management can facilitate lifestyle change, reduce clinic
and ambulatory blood pressure, and improve biomarkers of
cardiovascular risk. This new evidence supports the efficacy
of lifestyle modifications added to optimized medical
therapy in reducing blood pressure and improving
cardiovascular risk biomarkers in patients with resistant
hypertension. These findings need to be confirmed in larger
studies, and the persistence of benefit over extended
follow-up needs further study.},
Doi = {10.1007/s11906-023-01253-5},
Key = {fds371880}
}
@article{fds370322,
Author = {Avorgbedor, F and McCoy, TP and Silva, S and Blumenthal, JA and Merwin,
E and Yeo, S and Holditch-Davis, D},
Title = {Infant Outcomes in Hypertensive Women: Are there Moderating
Effects of Prenatal Care and Race/Ethnicity?},
Journal = {Matern Child Health J},
Volume = {27},
Number = {7},
Pages = {1277-1283},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1007/s10995-023-03661-0},
Abstract = {BACKGROUND: Hypertensive disorders of pregnancy is one of
the leading causes of adverse infant outcomes. Black women
are disproportionately affected by hypertensive disorders of
pregnancy, and it associated adverse outcomes. Adequate
prenatal care may improve adverse infant outcomes. However,
the evidence on adequate prenatal care improving birth
outcomes for women with hypertensive disorders of pregnancy
especially for Blacks is limited. This study examined the
role of adequate prenatal care and race/ethnicity as
moderators of hypertensive disorders of pregnancy on infant
outcomes. METHODS: The sample was obtained from the
2016-2019 Pregnancy Risk Assessment Monitoring Surveillance
dataset from North Carolina. We compared adequate prenatal
care among women with hypertensive disorders of pregnancy
(n = 610) to women without(n = 2,827), and women
with hypertensive disorders of pregnancy with adequate
prenatal care to women hypertensive disorders of pregnancy
with inadequate prenatal care. RESULTS: The weighted
prevalence of hypertensive disorders of pregnancy was 14.1%.
Adequate prenatal care was associated with better infant
outcomes for low birth weight (AOR = 0.72; 95%
CI = 0.58, 0.90) and preterm birth (AOR = 0.62; 95%
CI = 0.46, 0.82). Although these effects were not
moderated by Black race/ethnicity, Black women independently
also had worse outcomes for preterm birth (AOR = 1.59;
95% CI = 1.11, 2.28) and low birth weight
(AOR = 1.81; 95% CI = 1.42, 2.29). CONCLUSIONS:
Moderation of hypertensive disorders of pregnancy effects on
infant outcomes by prenatal care and race/ethnicity was not
found. Women with hypertensive disorders of pregnancy who
received inadequate prenatal care experienced worse adverse
birth outcomes compared to women without hypertensive
disorders of pregnancy. Strategies to improve prenatal care,
particularly among underserved populations at risk for
hypertensive disorders of pregnancy, need to be a public
health priority.},
Doi = {10.1007/s10995-023-03661-0},
Key = {fds370322}
}
@article{fds367444,
Author = {Marx, W and Manger, SH and Blencowe, M and Murray, G and Ho, FY-Y and Lawn,
S and Blumenthal, JA and Schuch, F and Stubbs, B and Ruusunen, A and Desyibelew, HD and Dinan, TG and Jacka, F and Ravindran, A and Berk, M and O'Neil, A},
Title = {Clinical guidelines for the use of lifestyle-based mental
health care in major depressive disorder: World Federation
of Societies for Biological Psychiatry (WFSBP) and
Australasian Society of Lifestyle Medicine (ASLM)
taskforce.},
Journal = {World J Biol Psychiatry},
Volume = {24},
Number = {5},
Pages = {333-386},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1080/15622975.2022.2112074},
Abstract = {OBJECTIVES: The primary objectives of these international
guidelines were to provide a global audience of clinicians
with (a) a series of evidence-based recommendations for the
provision of lifestyle-based mental health care in clinical
practice for adults with Major Depressive Disorder (MDD) and
(b) a series of implementation considerations that may be
applicable across a range of settings. METHODS:
Recommendations and associated evidence-based gradings were
based on a series of systematic literature searches of
published research as well as the clinical expertise of
taskforce members. The focus of the guidelines was eight
lifestyle domains: physical activity and exercise, smoking
cessation, work-directed interventions, mindfulness-based
and stress management therapies, diet, sleep, loneliness and
social support, and green space interaction. The following
electronic bibliographic databases were searched for
articles published prior to June 2020: PubMed, EMBASE, The
Cochrane Library (Cochrane Database of Systematic Reviews,
Cochrane Central Register of Controlled Trials (CENTRAL),
Cochrane Methodology Register), CINAHL, PsycINFO. Evidence
grading was based on the level of evidence specific to MDD
and risk of bias, in accordance with the World Federation of
Societies for Biological Psychiatry criteria. RESULTS: Nine
recommendations were formed. The recommendations with the
highest ratings to improve MDD were the use of physical
activity and exercise, relaxation techniques, work-directed
interventions, sleep, and mindfulness-based therapies (Grade
2). Interventions related to diet and green space were
recommended, but with a lower strength of evidence (Grade
3). Recommendations regarding smoking cessation and
loneliness and social support were based on expert opinion.
Key implementation considerations included the need for
input from allied health professionals and support networks
to implement this type of approach, the importance of
partnering such recommendations with behaviour change
support, and the need to deliver interventions using a
biopsychosocial-cultural framework. CONCLUSIONS:
Lifestyle-based interventions are recommended as a
foundational component of mental health care in clinical
practice for adults with Major Depressive Disorder, where
other evidence-based therapies can be added or used in
combination. The findings and recommendations of these
guidelines support the need for further research to address
existing gaps in efficacy and implementation research,
especially for emerging lifestyle-based approaches (e.g.
green space, loneliness and social support interventions)
where data are limited. Further work is also needed to
develop innovative approaches for delivery and models of
care, and to support the training of health professionals
regarding lifestyle-based mental health care.},
Doi = {10.1080/15622975.2022.2112074},
Key = {fds367444}
}
@misc{fds371519,
Author = {Smith, PJ and Blumenthal, JA},
Title = {Exercise and physical activity in the prevention and
treatment of depression},
Pages = {145-160},
Booktitle = {Routledge Handbook of Physical Activity and Mental
Health},
Year = {2023},
Month = {May},
ISBN = {9780415782999},
Key = {fds371519}
}
@article{fds371017,
Author = {Stonerock, GL and Gupta, RP and Blumenthal, JA},
Title = {Is exercise a viable therapy for anxiety? Systematic review
of recent literature and critical analysis.},
Journal = {Prog Cardiovasc Dis},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1016/j.pcad.2023.05.006},
Abstract = {OBJECTIVES: Exercise has been promoted as a treatment for a
variety of psychiatric conditions. The benefits of exercise
for depression are widely recognized, but the benefits of
exercise for anxiety are uncertain. Although several reviews
promoted exercise as a treatment for anxiety, concerns about
the quality of studies prompted us to provide a critical
review of the recent literature to re-assess the value of
exercise for treating anxiety. METHODS AND MATERIALS: We
conducted a systematic review of all peer-reviewed
randomized clinical trials (RCTs) among adults, published
between January 2014 and December 2021, with an exercise
intervention and anxiety as the a priori primary outcome.
Two reviewers independently extracted data from studies
meeting inclusion criteria, including sample
characteristics, exercise intervention, control conditions,
primary anxiety measure, relevant findings, and
methodological quality quantified by PEDro scores. RESULTS:
7240 published studies from CINAHL, EMBASE, MEDLINE, and
PsycINFO were screened in April 2022, with 1831 participants
across 25 eligible RCTs, of which 13 included elevated
anxiety at study entry as an eligibility criterion. Only two
of these 13 studies, and five of 12 studies of non-anxious
individuals, found anxiety to be reduced unequivocally with
exercise. Most studies suffered from significant
methodological limitations including concurrent therapies
and lack of intention-to-treat analyses. CONCLUSION: There
remains considerable uncertainty about the value of exercise
in reducing symptoms of anxiety, particularly among anxious
individuals. The paucity of methodologically sound studies
of patients with anxiety represents a significant gap in our
knowledge and calls for more research in the area. Word
count: 249.},
Doi = {10.1016/j.pcad.2023.05.006},
Key = {fds371017}
}
@article{fds371018,
Author = {Blumenthal, JA and Smith, PJ and Mabe, S and Hinderliter, A and Craighead, L and Watkins, LL and Ingle, K and Tyson, CC and Lin, P-H and Kraus, WE and Liao, L and Sherwood, A},
Title = {Effects of Lifestyle Modification on Psychosocial Function
in Patients With Resistant Hypertension: SECONDARY OUTCOMES
FROM THE TRIUMPH RANDOMIZED CLINICAL TRIAL.},
Journal = {J Cardiopulm Rehabil Prev},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1097/HCR.0000000000000801},
Abstract = {PURPOSE: In a secondary analysis of the TRIUMPH clinical
trial, psychological outcomes in patients with resistant
hypertension (RH) receiving a diet and exercise intervention
delivered in a cardiac rehabilitation setting were compared
with those receiving a similar prescription of diet and
exercise provided in a single counseling session by a health
educator. METHODS: One hundred forty patients with RH were
randomly assigned to a 4-mo program of dietary counseling,
behavioral weight management, and exercise (C-LIFE) or a
single counseling session providing standardized education
and physician advice (SEPA). Participants completed a
battery of questionnaires to assess psychological
functioning before and after the intervention. A global
measure of psychological functioning was derived from the
General Health Questionnaire (GHQ), Perceived Stress Scale
(PSS), Medical Outcomes Study 36-item Short Form Health
Survey, Spielberger State-Trait Anxiety Inventory, Hospital
Anxiety and Depression Scale (HADS), Beck Depression
Inventory-II, and Patient-Reported Outcomes Measurement
Information System (PROMIS) Anger scale. RESULTS:
Participants in the C-LIFE intervention achieved greater
improvements in psychological functioning compared with SEPA
(C-LIFE: 58.9 [56.1, 61.8] vs SEPA: 66.5 [62.1, 70.9]; P =
.024). Greater improvements were especially evident for the
GHQ, PSS, and HADS. Examination of mediation revealed that
greater weight loss (B =-0.17, P = .004) and improved oxygen
uptake (B =-0.12, P = .044) were associated with improved
psychological functioning. CONCLUSION: Compared with
standard education and physician advice, a structured
program of diet and exercise not only reduced blood pressure
but also improved psychological functioning in patients with
RH.},
Doi = {10.1097/HCR.0000000000000801},
Key = {fds371018}
}
@article{fds368555,
Author = {Avorgbedor, F and Blumenthal, JA and Hinderliter, A and Ingle, K and Lin, P-H and Craighead, L and Tyson, C and Kraus, W and Sherwood, A and Smith, PJ},
Title = {Inflammation moderates the effects of lifestyle modification
on neurocognition among individuals with resistant
hypertension.},
Journal = {J Clin Hypertens (Greenwich)},
Volume = {25},
Number = {1},
Pages = {106-110},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1111/jch.14591},
Abstract = {Individuals with resistant hypertension (RH) have the
greatest risk of cerebrovascular disease and cognitive
impairment among individuals with hypertension. Elevated
levels of pro-inflammatory cytokines may represent a
critical yet unexamined factor influencing the impact of
healthy lifestyle changes on cognitive function. We explored
the influence of inflammation on changes in cognition
following lifestyle modification among individuals with RH
participating in the TRIUMPH clinical trial. One hundred
forty participants with RH completed a battery of
neurocognitive tests along with the inflammatory marker
C-reactive protein (hsCRP) and were subsequently randomized
to an intensive 4-month lifestyle modification intervention
or to education and physician advice control. Results
indicated that the effects of lifestyle modification on
Executive Function and Learning were moderated by
pre-intervention hsCRP levels (P = .049), with treatment
efficacy increasing across levels of baseline inflammation
levels (low: d = 0.12; mild: d = 0.43; moderate:
d = 0.81). We conclude that inflammatory profiles may help
identify individuals more likely to improve executive
functioning resulting from lifestyle modification.},
Doi = {10.1111/jch.14591},
Key = {fds368555}
}
@article{fds370064,
Author = {Blumenthal, JA and Rozanski, A},
Title = {Exercise as a therapeutic modality for the prevention and
treatment of depression.},
Journal = {Prog Cardiovasc Dis},
Volume = {77},
Pages = {50-58},
Year = {2023},
url = {http://dx.doi.org/10.1016/j.pcad.2023.02.008},
Abstract = {While maintaining an active lifestyle and engaging in
regular exercise are known to promote cardiovascular (CV)
health, increasing evidence has emerged to indicate that
these lifestyle behaviors also can promote psychological
health and well-being. This has led to research to determine
if exercise can serve as a potential therapeutic modality
for major depressive disorder (MDD), which is a leading
cause of mental-health impairment and overall disability
worldwide. The strongest evidence to support this use comes
from an increasing number of randomized clinical trials
(RCTs) that have compared exercise to usual care, placebo
controls, or established therapies in healthy adults and in
various clinical populations. The relatively large number of
RCTs has led to numerous reviews and meta-analyses, which
generally have been concordant in indicating that exercise
ameliorates depressive symptoms, improves self-esteem, and
enhances various aspects of quality of life. Together, these
data indicate that exercise should be considered as a
therapeutic modality for improving CV health and
psychological well-being. The emerging evidence also has led
to a new proposed subspecialty of "lifestyle psychiatry",
which promotes the use of exercise as an adjunctive
treatment for patients with MDD. Indeed, some medical
organizations have now endorsed lifestyle-based approaches
as foundational aspects of depression management, with
adoption of exercise as a treatment option for MDD. This
review summarizes research in the area and provides
practical suggestions for the use of exercise in clinical
practice.},
Doi = {10.1016/j.pcad.2023.02.008},
Key = {fds370064}
}
@article{fds370644,
Author = {Rozanski, A and Blumenthal, JA and Hinderliter, AL and Cole, S and Lavie, CJ},
Title = {Cardiology and lifestyle medicine.},
Journal = {Prog Cardiovasc Dis},
Volume = {77},
Pages = {4-13},
Year = {2023},
url = {http://dx.doi.org/10.1016/j.pcad.2023.04.004},
Abstract = {Poor lifestyle habits, such as physical inactivity and poor
diets, are highly prevalent within society and even more so
among patients with chronic disease. The need to stem poor
lifestyle habits has led to the development of a new field
of Lifestyle Medicine, whose mission is to prevent, treat,
and even reverse chronic diseases through lifestyle
interventions. Three fields within Cardiology relate to this
mission: Cardiac Rehabilitation, Preventive Cardiology, and
Behavioral Cardiology. Each of these three fields have
contributed substantially to the reduction of cardiovascular
disease (CVD) morbidity and mortality. The historic
contributions of these three cardiac fields are reviewed as
well as the challenges each of these fields has faced in
optimizing the application of lifestyle medicine practices.
A shared agenda between Cardiology and the American College
of Lifestyle Medicine could further the utilization of
behavioral interventions. This review suggests seven steps
that could be shared by these organizations and other
medical societies. First, there is a need to develop and
promulgate the assessment of lifestyle factors as "vital
signs" during patient visits. Second, developing a strong
partnership between the fields of Cardiology and Physiatry
could improve important aspects of cardiac care, including a
potential redesign of cardiac stress testing. Third,
behavioral evaluations should be optimized at patients'
entrée points into medical care since these may be
considered "windows of opportunity". Fourth, there is a need
to broaden cardiac rehabilitation into inexpensive programs
and make this program eligible for patients with risk
factors but no known CVD. Fifth, lifestyle medicine
education should be integrated into the core competencies
for relevant specialties. Sixth, there is a need for
inter-societal advocacy to promote lifestyle medicine
practices. Seventh, the well-being effects of healthy
lifestyle behaviors, such as their impact on one's sense of
vitality, should be emphasized.},
Doi = {10.1016/j.pcad.2023.04.004},
Key = {fds370644}
}
@article{fds371019,
Author = {Smith, PJ and Sherwood, A and Avorgbedor, F and Ingle, KK and Kraus, WE and Hinderliter, AE and Blumenthal, JA},
Title = {Sleep Quality, Metabolic Function, Physical Activity, and
Neurocognition Among Individuals with Resistant
Hypertension.},
Journal = {J Alzheimers Dis},
Volume = {93},
Number = {3},
Pages = {995-1006},
Year = {2023},
url = {http://dx.doi.org/10.3233/JAD-230029},
Abstract = {BACKGROUND: Resistant hypertension (RH) is a major risk
factor for stroke, cognitive decline, and dementia. Sleep
quality is increasingly suggested to play an important role
linking RH to cognitive outcomes, although the mechanisms
linking sleep quality to poor cognitive function have yet to
be fully delineated. OBJECTIVE: To delineate biobehavioral
mechanisms linking sleep quality, metabolic function, and
cognitive function among 140 overweight/obese adults with RH
in the TRIUMPH clinical trial. METHODS: Sleep quality was
indexed using actigraphy measures of sleep quality and sleep
fragmentation, as well as self-reported sleep quality from
the Pittsburgh Sleep Quality Index (PSQI). Cognitive
function was assessed using a 45-minute battery assessing
executive function, processing speed, and memory.
Participants were randomized to a cardiac
rehabilitation-based lifestyle program (C-LIFE) or a
standardized education and physician advice condition (SEPA)
for 4 months. RESULTS: Better sleep quality at baseline was
associated with better executive function (B = 0.18
p = 0.027), as well as greater fitness (B = 0.27,
p = 0.007) and lower HBA1c (B = -0.25,
p = 0.010). Cross-sectional analyses revealed that the
sleep quality executive function association was mediated by
HBA1c (B = 0.71 [0.05, 2.05]). C-LIFE improved sleep
quality (-1.1 [-1.5, -0.6] versus+-0.1 [-0.8, 0.7]) and
actigraphy steps (+922 [529, 1316] versus+56 [-548, 661]),
with actigraphy mediating improvements in executive function
(B = 0.40 [0.02, 1.07]). CONCLUSION: Better metabolic
function and improved physical activity patterns levels play
important roles linking sleep quality and executive function
in RH.},
Doi = {10.3233/JAD-230029},
Key = {fds371019}
}
%% Bourassa, Kyle
@article{fds366153,
Author = {Bourassa, KJ and Moffitt, TE and Harrington, H and Houts, R and Poulton,
R and Ramrakha, S and Rasmussen, LJH and Wertz, J and Caspi,
A},
Title = {Childhood Adversity and Midlife Health: Shining a Light on
the Black Box of Psychosocial Mechanisms.},
Journal = {Prevention Science : the Official Journal of the Society for
Prevention Research},
Volume = {24},
Number = {5},
Pages = {817-828},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1007/s11121-022-01431-y},
Abstract = {Adverse childhood experiences (ACEs) are associated with
poorer health, which has spurred public health efforts to
reduce the number of adverse events children experience.
Unfortunately, it is unlikely that all ACEs can be
prevented. For adults who already experienced ACEs in
childhood, what psychological, social, and behavioral
intervention targets might reduce risk for negative health
outcomes? To provide insight into the "black box" of
psychosocial mechanisms linking ACEs to poor health, our
study used data from the Dunedin Study, a longitudinal
cohort assessed from birth to age 45. Mediation models
(N = 859) were used to examine whether candidate
psychosocial variables in adulthood explained the
association between childhood ACEs and health in midlife.
Potential psychosocial mediators included stressful life
events, perceived stress, negative emotionality, and health
behaviors. Children who experienced more ACEs had poorer
health in midlife. They also had significantly more
stressful life events, more perceived stress, more negative
emotionality, and unhealthier behaviors as adults. These
mediators were each independently associated with poorer
health in midlife and statistically mediated the association
between ACEs and midlife health. Health behaviors evidenced
the strongest indirect effect from ACEs to midlife health.
Together, these psychosocial mediators accounted for the
association between ACEs in childhood and health three
decades later. Public health efforts to mitigate the health
consequences of ACEs could aim to reduce the stressful life
events people experience, reduce negative emotionality,
reduce perceived stress, or improve health behaviors among
adults who experienced childhood adversity.},
Doi = {10.1007/s11121-022-01431-y},
Key = {fds366153}
}
@article{fds370508,
Author = {Bourassa, KJ and Caspi, A and Brennan, GM and Hall, KS and Harrington,
H and Houts, R and Kimbrel, NA and Poulton, R and Ramrakha, S and Taylor,
GA and Moffitt, TE},
Title = {Which Types of Stress Are Associated With Accelerated
Biological Aging? Comparing Perceived Stress, Stressful Life
Events, Childhood Adversity, and Posttraumatic Stress
Disorder.},
Journal = {Psychosom Med},
Volume = {85},
Number = {5},
Pages = {389-396},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1097/PSY.0000000000001197},
Abstract = {OBJECTIVE: Stress and stressful events are associated with
poorer health; however, there are multiple ways to
conceptualize and measure stress and stress responses. One
physiological mechanism through which stress could result in
poorer health is accelerated biological aging. This study
tested which types of stress were associated with
accelerated biological aging in adulthood. METHODS: Studying
955 participants from the Dunedin Longitudinal Study, we
tested whether four types of stress assessed from ages 32 to
45 years-perceived stress, number of stressful life events,
adverse childhood experiences, and posttraumatic stress
disorder-were associated with accelerated biological aging.
RESULTS: Higher levels of all four measures of stress were
significantly associated with accelerated aging in separate
models. In a combined model, more perceived stress and more
stressful life events remained associated with faster aging,
and the stress measures explained 6.9% of the variance in
aging. The magnitudes of the associations between the four
measures of stress and biological aging were comparable to
associations for smoking and low education, two established
risk factors for accelerated aging. People with high levels
of perceived stress, numerous adverse childhood experiences
(4+), high stressful life event counts, or posttraumatic
stress disorder were aging an additional estimated 2.4
months, 1.1 additional months, 1.4 months, and 1.4 months
per year, respectively. CONCLUSIONS: Assessing stress,
particularly perceived stress, could help identify people at
risk of accelerated aging. Intervening to treat stress or
the health-relevant sequelae of stress could potentially
slow the rate at which people are aging, improving their
health as they age.},
Doi = {10.1097/PSY.0000000000001197},
Key = {fds370508}
}
%% Brennan, Grace
@article{fds375249,
Author = {Brennan, GM and Moffitt, TE and Bourassa, KJ and Harrington, H and Hogan, S and Houts, RM and Poulton, R and Ramrakha, S and Caspi,
A},
Title = {The Continuity of Adversity: Negative Emotionality Links
Early Life Adversity With Adult Stressful Life
Events},
Journal = {Clinical Psychological Science : a Journal of the
Association for Psychological Science},
Publisher = {SAGE Publications},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1177/21677026231220337},
Abstract = {<jats:p> Adversity that exhibits continuity across the life
course has long-term detrimental effects on physical and
mental health. Using 920 participants from the Dunedin
Study, we tested the following hypotheses: (a) Children
(ages 3–15) who experienced adversity would also tend to
experience adversity in adulthood (ages 32–45), and (2)
interim personality traits in young adulthood (ages 18–26)
would help account for this longitudinal association.
Children who experienced more adversity tended to also
experience more stressful life events as adults, β = 0.11,
95% confidence interval [CI] = [0.04, 0.18], p = .002.
Negative emotionality—particularly its subfacet
alienation, characterized by mistrust of others—helped
explain this childhood-to-midlife association (indirect
effect: β = 0.06, 95% CI = [0.04, 0.09], p < .001).
Results were robust to adjustment for sex, socioeconomic
origins, childhood IQ, preschool temperament, and other
young-adult personality traits. Prevention of early life
adversity and treatment of young-adult negative emotionality
may reduce vulnerability to later life stress and thereby
promote the health of aging adults. </jats:p>},
Doi = {10.1177/21677026231220337},
Key = {fds375249}
}
@article{fds373039,
Author = {Brennan, GM and Moffitt, TE and Ambler, A and Harrington, H and Hogan,
S and Houts, RM and Mani, R and Poulton, R and Ramrakha, S and Caspi,
A},
Title = {Tracing the origins of midlife despair: association of
psychopathology during adolescence with a syndrome of
despair-related maladies at midlife.},
Journal = {Psychological Medicine},
Volume = {53},
Number = {16},
Pages = {7569-7580},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1017/s0033291723001320},
Abstract = {<h4>Background</h4>Midlife adults are experiencing a crisis
of deaths of despair (i.e. deaths from suicide, drug
overdose, and alcohol-related liver disease). We tested the
hypothesis that a syndrome of despair-related maladies at
midlife is preceded by psychopathology during
adolescence.<h4>Methods</h4>Participants are members of a
representative cohort of 1037 individuals born in Dunedin,
New Zealand in 1972-73 and followed to age 45 years, with
94% retention. Adolescent mental disorders were assessed in
three diagnostic assessments at ages 11, 13, and 15 years.
Indicators of despair-related maladies across four domains -
suicidality, substance misuse, sleep problems, and pain -
were assessed at age 45 using multi-modal measures including
self-report, informant-report, and national register
data.<h4>Results</h4>We identified and validated a syndrome
of despair-related maladies at midlife involving
suicidality, substance misuse, sleep problems, and pain.
Adults who exhibited a more severe syndrome of
despair-related maladies at midlife tended to have had
early-onset emotional and behavioral disorders [<i>β</i> =
0.23, 95% CI (0.16-0.30), <i>p</i> < 0.001], even after
adjusting for sex, childhood SES, and childhood IQ. A more
pronounced midlife despair syndrome was observed among
adults who, as adolescents, were diagnosed with a greater
number of mental disorders [<i>β</i> = 0.26, 95% CI
(0.19-0.33), <i>p</i> < 0.001]. Tests of diagnostic
specificity revealed that associations generalized across
different adolescent mental disorders.<h4>Conclusions</h4>Midlife
adults who exhibited a more severe syndrome of
despair-related maladies tended to have had psychopathology
as adolescents. Prevention and treatment of adolescent
psychopathology may mitigate despair-related maladies at
midlife and ultimately reduce deaths of despair.},
Doi = {10.1017/s0033291723001320},
Key = {fds373039}
}
@article{fds373038,
Author = {Bourassa, KJ and Caspi, A and Brennan, GM and Hall, KS and Harrington,
H and Houts, R and Kimbrel, NA and Poulton, R and Ramrakha, S and Taylor,
GA and Moffitt, TE},
Title = {Which Types of Stress Are Associated With Accelerated
Biological Aging? Comparing Perceived Stress, Stressful Life
Events, Childhood Adversity, and Posttraumatic Stress
Disorder.},
Journal = {Psychosom Med},
Volume = {85},
Number = {5},
Pages = {389-396},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1097/PSY.0000000000001197},
Abstract = {OBJECTIVE: Stress and stressful events are associated with
poorer health; however, there are multiple ways to
conceptualize and measure stress and stress responses. One
physiological mechanism through which stress could result in
poorer health is accelerated biological aging. This study
tested which types of stress were associated with
accelerated biological aging in adulthood. METHODS: Studying
955 participants from the Dunedin Longitudinal Study, we
tested whether four types of stress assessed from ages 32 to
45 years-perceived stress, number of stressful life events,
adverse childhood experiences, and posttraumatic stress
disorder-were associated with accelerated biological aging.
RESULTS: Higher levels of all four measures of stress were
significantly associated with accelerated aging in separate
models. In a combined model, more perceived stress and more
stressful life events remained associated with faster aging,
and the stress measures explained 6.9% of the variance in
aging. The magnitudes of the associations between the four
measures of stress and biological aging were comparable to
associations for smoking and low education, two established
risk factors for accelerated aging. People with high levels
of perceived stress, numerous adverse childhood experiences
(4+), high stressful life event counts, or posttraumatic
stress disorder were aging an additional estimated 2.4
months, 1.1 additional months, 1.4 months, and 1.4 months
per year, respectively. CONCLUSIONS: Assessing stress,
particularly perceived stress, could help identify people at
risk of accelerated aging. Intervening to treat stress or
the health-relevant sequelae of stress could potentially
slow the rate at which people are aging, improving their
health as they age.},
Doi = {10.1097/PSY.0000000000001197},
Key = {fds373038}
}
%% Briggs-King, Ernestine C.
@article{fds373871,
Author = {Briggs, E and Hanson, R and Klika, JB and LeBlanc, S and Maddux, J and Merritt, D and Palusci, V and Panlilio, CC and Roygardner, D and Schelbe, L and Stormer, B and Valentino, K and Vaughan-Eden, V and Barboza, G},
Title = {Addressing Systemic Racism in the American Professional
Society on the Abuse of Children Publications.},
Journal = {Child Maltreat},
Volume = {28},
Number = {4},
Pages = {550-555},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1177/10775595231191394},
Abstract = {The United States continues to grapple with longstanding
policies and systems that have adversely impacted
historically marginalized communities who identify (and are
racialized) as non-White. These stem from a legacy of
structural and systemic racism, and the long-term
consequences of sanctioned colonization. This legacy rests
upon a field of scholarly research that is similarly fraught
with white supremacy. As a field, we must examine the
process of producing and publishing the body of evidence
that has codified harmful policies and practices. Although
racial and ethnic disparities have been discussed for
decades in the child welfare and health systems, systemic
racism has received comparatively little attention in
academic research and journals. In this commentary, the
authors detail concrete steps over the coming years that
will advance diversity, equity, inclusion and justice
through American Professional Society on the Abuse of
Children's (APSACs) flagship journal, Child Maltreatment.
The journal is committed to anti-racist publication
processes, such that the journal pledges to develop
procedures, processes, structures, and culture for scholarly
research that promotes diversity, equity, inclusion, and
justice in all forms.},
Doi = {10.1177/10775595231191394},
Key = {fds373871}
}
@article{fds369784,
Author = {Hodgdon, HB and Lord, KA and Suvak, MK and Martin, L and Briggs, EC and Beserra, K},
Title = {Predictors of symptom severity and change among youth in
trauma-informed residential care.},
Journal = {Child Abuse Negl},
Volume = {137},
Pages = {106056},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1016/j.chiabu.2023.106056},
Abstract = {BACKGROUND: Trauma-informed residential care is an intensive
intervention setting for youth, but research on its
effectiveness is limited and yields mixed findings.
OBJECTIVES: The study aims were to; 1) evaluate change over
time of mental health (MH) symptoms over 21 months of
trauma-informed residential care, and 2) examine the
influence of demographic and risk factor variables (e.g.
age, gender, trauma and placement history) on baseline
symptoms and treatment response. PARTICIPANTS: A sample of
547 youth ages 12 to18 in trauma-informed residential care
(M age = 15.84 (SD = 1.56), 43.2 % male) were examined,
with notable attrition over the study period. METHOD: Latent
curve analysis (LCA) was used to estimate MH symptom
severity at intake and change during 21 months (8
assessments total, intake and every 3 months) of care.
RESULTS: Trauma-informed residential care was associated
with significant reductions in symptoms of PTSD
(d = -0.76), depression (d = -0.59), dissociation
(d = -0.60), psychological dysregulation (d = -0.94),
and externalizing (d = -0.31), but not internalizing
(d = 0.01) problems. Females had greater symptoms at
intake across multiple indicators and showed equivalent or
greater treatment response than males, although both groups
improved. Neither cumulative trauma nor previous placement
were associated with attenuated treatment response, but
trauma history was positively associated with severity of
multiple clinical measures at intake. CONCLUSIONS:
Trauma-informed residential treatment can lead to reductions
in clinical symptoms, even among multiply trauma-impacted
youth. The extent of youth's trauma history did not
negatively influence treatment response.},
Doi = {10.1016/j.chiabu.2023.106056},
Key = {fds369784}
}
@article{fds373872,
Author = {Richardson, SM and Pflieger, JC and Hisle-Gorman, E and Briggs, EC and Fairbank, JA and Stander, VA},
Title = {Family separation from military service and children's
externalizing symptoms: Exploring moderation by non-military
spouse employment, family financial stress, marital quality,
and the parenting alliance},
Journal = {Social Development (Oxford, England)},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1111/sode.12713},
Abstract = {Military separation is a well-documented vulnerability point
for service members, yet little is known regarding how
children fare across this transition. The current study
examined 909 military-connected children from the Millennium
Cohort Family Study (Wave 1 Mage = 3.88 years, SD =.095)
across a 3-year period to explore whether separation
predicted child externalizing symptoms over and above Wave 1
externalizing levels, by comparing separated versus not
separated military families over time. We also explored if
non-military spouse employment, financial stress, marital
quality, or parenting alliance moderated the relation of
separation with child externalizing. Data were collected via
a parent-reported online questionnaire and administrative
military records. Results showed that separation was
unrelated to externalizing. However, moderation analyses
suggested that for those who separated, non-military
spouses’ employment prior to separation was related to
less externalizing, whereas the parenting alliance was
related to less externalizing only for families who remained
in the military. Recommendations include assistance with
spouse employment prior to military separation and parenting
support throughout military service.},
Doi = {10.1111/sode.12713},
Key = {fds373872}
}
%% Cabeza, Roberto
@article{fds376852,
Author = {Morales-Torres, R and Wing, EA and Deng, L and Davis, SW and Cabeza,
R},
Title = {Visual recognition memory of scenes is driven by
categorical, not sensory, visual representations.},
Journal = {The Journal of neuroscience : the official journal of the
Society for Neuroscience},
Pages = {e1479232024},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1523/jneurosci.1479-23.2024},
Abstract = {When we perceive a scene, our brain processes various types
of visual information simultaneously, ranging from sensory
features, such as line orientations and colors, to
categorical features, such as objects and their
arrangements. Whereas the role of sensory and categorical
visual representations in predicting subsequent memory has
been studied using isolated objects, their impact on memory
for complex scenes remains largely unknown. To address this
gap, we conducted an fMRI study in which female and male
participants encoded pictures of familiar scenes (e.g., an
airport picture) and later recalled them, while rating the
vividness of their visual recall. Outside the scanner,
participants had to distinguish each seen scene (e.g., an
airport picture) from three similar lures (e.g., 3 airport
pictures). We modeled the sensory and categorical visual
features of multiple scenes using both early and late layers
of a deep convolutional neural network. Then, we applied
representational similarity analysis to determine which
brain regions represented stimuli in accordance with the
sensory and categorical models. We found that categorical,
but not sensory, representations predicted subsequent
memory. In line with the previous result, only for the
categorical model, the average recognition performance of
each scene exhibited a positive correlation with the average
visual dissimilarity between the item in question and its
respective lures. These results strongly suggest that even
in memory tests that ostensibly rely solely on visual cues
(such as force-choice visual recognition with similar
distractors), memory decisions for scenes may be primarily
influenced by categorical rather than sensory
representations.<b>Significance Statement</b> Our memory for
real-world scenes often comprises a tableau of complex
visual features, but recent findings challenge the view that
our memories of such stimuli rely on purely visual
information. Instead, it appears that our memory for scenes
is heavily influenced by higher-level categorical
information. Analyzing cortical representations in regions
responsive to both categorical and sensory features, we
discovered that only the former can reliably predict memory
outcomes. Moreover, the distinctiveness of scenes in terms
of their categoric features among similar examples is
positively associated with our ability to accurately
recognize previously encountered scenes. In essence, this
study sheds light on how our brains rely on categorical
information to recognize natural scenes.},
Doi = {10.1523/jneurosci.1479-23.2024},
Key = {fds376852}
}
@article{fds375232,
Author = {Huang, S and Howard, CM and Hovhannisyan, M and Ritchey, M and Cabeza,
R and Davis, SW},
Title = {Hippocampal Functions Modulate Transfer-Appropriate Cortical
Representations Supporting Subsequent Memory.},
Journal = {J Neurosci},
Volume = {44},
Number = {1},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1523/JNEUROSCI.1135-23.2023},
Abstract = {The hippocampus plays a central role as a coordinate system
or index of information stored in neocortical loci.
Nonetheless, it remains unclear how hippocampal processes
integrate with cortical information to facilitate successful
memory encoding. Thus, the goal of the current study was to
identify specific hippocampal-cortical interactions that
support object encoding. We collected fMRI data while 19
human participants (7 female and 12 male) encoded images of
real-world objects and tested their memory for object
concepts and image exemplars (i.e., conceptual and
perceptual memory). Representational similarity analysis
revealed robust representations of visual and semantic
information in canonical visual (e.g., occipital cortex) and
semantic (e.g., angular gyrus) regions in the cortex, but
not in the hippocampus. Critically, hippocampal functions
modulated the mnemonic impact of cortical representations
that are most pertinent to future memory demands, or
transfer-appropriate representations Subsequent perceptual
memory was best predicted by the strength of visual
representations in ventromedial occipital cortex in
coordination with hippocampal activity and pattern
information during encoding. In parallel, subsequent
conceptual memory was best predicted by the strength of
semantic representations in left inferior frontal gyrus and
angular gyrus in coordination with either hippocampal
activity or semantic representational strength during
encoding. We found no evidence for transfer-incongruent
hippocampal-cortical interactions supporting subsequent
memory (i.e., no hippocampal interactions with cortical
visual/semantic representations supported
conceptual/perceptual memory). Collectively, these results
suggest that diverse hippocampal functions flexibly modulate
cortical representations of object properties to satisfy
distinct future memory demands.Significance Statement The
hippocampus is theorized to index pieces of information
stored throughout the cortex to support episodic memory. Yet
how hippocampal processes integrate with cortical
representation of stimulus information remains unclear.
Using fMRI, we examined various forms of
hippocampal-cortical interactions during object encoding in
relation to subsequent performance on conceptual and
perceptual memory tests. Our results revealed novel
hippocampal-cortical interactions that utilize semantic and
visual representations in transfer-appropriate manners:
conceptual memory supported by hippocampal modulation of
frontoparietal semantic representations, and perceptual
memory supported by hippocampal modulation of occipital
visual representations. These findings provide important
insights into the neural mechanisms underlying the formation
of information-rich episodic memory and underscore the value
of studying the flexible interplay between brain regions for
complex cognition.},
Doi = {10.1523/JNEUROSCI.1135-23.2023},
Key = {fds375232}
}
@article{fds375274,
Author = {Cabeza, R and Düzel, E},
Title = {Endel Tulving (1927-2023).},
Journal = {Science (New York, N.Y.)},
Volume = {382},
Number = {6677},
Pages = {1365},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1126/science.adn2158},
Abstract = {Explorer, innovator, and theorist of human
memory.},
Doi = {10.1126/science.adn2158},
Key = {fds375274}
}
@article{fds374274,
Author = {Naspi, L and Stensholt, C and Karlsson, AE and Monge, ZA and Cabeza,
R},
Title = {Effects of Aging on Successful Object Encoding: Enhanced
Semantic Representations Compensate for Impaired Visual
Representations.},
Journal = {The Journal of neuroscience : the official journal of the
Society for Neuroscience},
Volume = {43},
Number = {44},
Pages = {7337-7350},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1523/jneurosci.2265-22.2023},
Abstract = {Although episodic memory and visual processing decline
substantially with healthy aging, semantic knowledge is
generally spared. There is evidence that older adults'
spared semantic knowledge can support episodic memory. Here,
we used functional magnetic resonance imaging (fMRI)
combined with representational similarity analyses (RSAs) to
examine how novel visual and preexisting semantic
representations at encoding predict subjective memory
vividness at retrieval. Eighteen young and seventeen older
adults (female and male participants) encoded images of
objects during fMRI scanning and recalled these images while
rating the vividness of their memories. After scanning,
participants discriminated between studied images and
similar lures. RSA based on a deep convolutional neural
network and normative concept feature data were used to link
patterns of neural activity during encoding to visual and
semantic representations. Relative to young adults, the
specificity of activation patterns for visual features was
reduced in older adults, consistent with dedifferentiation.
However, the specificity of activation patterns for semantic
features was enhanced in older adults, consistent with
hyperdifferentiation. Despite dedifferentiation, visual
representations in early visual cortex (EVC) predicted high
memory vividness in both age groups. In contrast, semantic
representations in lingual gyrus (LG) and fusiform gyrus
(FG) were associated with high memory vividness only in the
older adults. Intriguingly, data suggests that older adults
with lower specificity of visual representations in
combination with higher specificity of semantic
representations tended to rate their memories as more vivid.
Our findings suggest that memory vividness in aging relies
more on semantic representations over anterior regions,
potentially compensating for age-related dedifferentiation
of visual information in posterior regions.<b>SIGNIFICANCE
STATEMENT</b> Normal aging is associated with impaired
memory for events while semantic knowledge might even
improve. We investigated the effects of aging on the
specificity of visual and semantic information in the brain
when viewing common objects and how this information enables
subsequent memory vividness for these objects. Using
functional magnetic resonance imaging (fMRI) combined with
modeling of the stimuli we found that visual information was
represented with less specificity in older than young adults
while still supporting memory vividness. In contrast
semantic information supported memory vividness only in
older adults and especially in those individuals that had
the lowest specificity of visual information. These findings
provide evidence for a spared semantic memory system
increasingly recruited to compensate for degraded visual
representations in older age.},
Doi = {10.1523/jneurosci.2265-22.2023},
Key = {fds374274}
}
@article{fds373554,
Author = {Becker, M and Yu, Y and Cabeza, R},
Title = {The influence of insight on risky decision making and
nucleus accumbens activation.},
Journal = {Scientific reports},
Volume = {13},
Number = {1},
Pages = {17159},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1038/s41598-023-44293-2},
Abstract = {During insightful problem solving, the solution appears
unexpectedly and is accompanied by the feeling of an AHA!.
Research suggests that this affective component of insight
can have consequences beyond the solution itself by
motivating future behavior, such as risky (high reward and
high uncertainty) decision making. Here, we investigate the
behavioral and neural support for the motivational role of
AHA in decision making involving monetary choices. The
positive affect of the AHA! experience has been linked to
internal reward. Reward in turn has been linked to
dopaminergic signal transmission in the Nucleus Accumbens
(NAcc) and risky decision making. Therefore, we hypothesized
that insight activates reward-related brain areas,
modulating risky decision making. We tested this hypothesis
in two studies. First, in a pre-registered online study
(Study 1), we demonstrated the behavioral effect of
insight-related increase in risky decision making using a
visual Mooney identification paradigm. Participants were
more likely to choose the riskier monetary payout when they
had previously solved the Mooney image with high compared to
low accompanied AHA!. Second, in an fMRI study (Study 2), we
measured the effects of insight on NAcc activity using a
similar Mooney identification paradigm to the one of Study
1. Greater NAcc activity was found when participants solved
the Mooney image with high vs low AHA!. Taken together, our
results link insight to enhanced NAcc activity and a
preference for high but uncertain rewards, suggesting that
insight enhances reward-related brain areas possibly via
dopaminergic signal transmission, promoting risky decision
making.},
Doi = {10.1038/s41598-023-44293-2},
Key = {fds373554}
}
@article{fds373555,
Author = {Gjorgieva, E and Morales-Torres, R and Cabeza, R and Woldorff,
MG},
Title = {Neural retrieval processes occur more rapidly for visual
mental images that were previously encoded with
high-vividness.},
Journal = {Cereb Cortex},
Volume = {33},
Number = {19},
Pages = {10234-10244},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1093/cercor/bhad278},
Abstract = {Visual mental imagery refers to our ability to experience
visual images in the absence of sensory stimulation. Studies
have shown that visual mental imagery can improve episodic
memory. However, we have limited understanding of the neural
mechanisms underlying this improvement. Using
electroencephalography, we examined the neural processes
associated with the retrieval of previously generated visual
mental images, focusing on how the vividness at generation
can modulate retrieval processes. Participants viewed word
stimuli referring to common objects, forming a visual mental
image of each word and rating the vividness of the mental
image. This was followed by a surprise old/new recognition
task. We compared retrieval performance for items rated as
high- versus low-vividness at encoding. High-vividness items
were retrieved with faster reaction times and higher
confidence ratings in the memory judgment. While controlling
for confidence, neural measures indicated that
high-vividness items produced an earlier decrease in
alpha-band activity at retrieval compared with low-vividness
items, suggesting an earlier memory reinstatement. Even when
low-vividness items were remembered with high confidence,
they were not retrieved as quickly as high-vividness items.
These results indicate that when highly vivid mental images
are encoded, the speed of their retrieval occurs more
rapidly, relative to low-vivid items.},
Doi = {10.1093/cercor/bhad278},
Key = {fds373555}
}
@article{fds371261,
Author = {Garcia De La Santa Ramos and A and Cabeza, R and Villanueva,
A},
Title = {Calibration free eye tracking solution for mobile and
embedded devices},
Journal = {Eye Tracking Research and Applications Symposium
(ETRA)},
Year = {2023},
Month = {May},
ISBN = {9798400701504},
url = {http://dx.doi.org/10.1145/3588015.3589539},
Abstract = {In this study we propose a competent low-cost eye tracking
solution that is able to run on any mobile device,
independently of the hardware that is equipped with. The
rapid evolution of technologies has enabled to work with
many neural network structures that some years ago were out
of reach. The project will start from a solution which
Irisbond (https://www.irisbond.com/) company has been
working on, which gives precision values of 3 and 6 degrees
for calibration and calibration-free use cases respectively.
The goal of the solution is to try to develop a usable
solution in the Augmented and Alternative Communication
(AAC) field across different types of devices, from mobile
to embedded devices. To achieve such an objective, two main
goals have been set out during this study. One the one hand
I (we) aim at removing the initial calibration step to reach
a calibration-free solution. On the other hand, I (we) seek
to separate the functionality of a software into
independent, interchangeable modules to fit the different
target device limitations.},
Doi = {10.1145/3588015.3589539},
Key = {fds371261}
}
@article{fds369070,
Author = {Stern, Y and Albert, M and Barnes, CA and Cabeza, R and Pascual-Leone,
A and Rapp, PR},
Title = {A framework for concepts of reserve and resilience in
aging.},
Journal = {Neurobiology of aging},
Volume = {124},
Pages = {100-103},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1016/j.neurobiolaging.2022.10.015},
Abstract = {The study of factors, across species, that allow some
individuals to age more successfully than others has
important implications for individual wellbeing as well as
health education, policy and intervention. Design of studies
and communication across investigators in this area has been
hampered by a diversity of terminology. The Collaboratory on
Research Definitions for Reserve and Resilience in Cognitive
Aging and Dementia was funded by the National Institute on
Aging and established in 2019 as a 3-year process of
developing consensus definitions and research guidelines.
The proposed Framework is based on an iterative process
including 3 annual Workshops, focused workgroups, and input
from numerous international investigators. It suggests the
overarching term: resilience, and presents operational
definitions for 3 concepts: cognitive reserve, brain
maintenance, and brain reserve. Twelve pilot studies that
integrate these definitions are presented. The use of a
common vocabulary and operational definitions will
facilitate even greater progress in understanding the
factors that are associated with successful
aging.},
Doi = {10.1016/j.neurobiolaging.2022.10.015},
Key = {fds369070}
}
@article{fds365720,
Author = {Gjorgieva, E and Geib, BR and Cabeza, R and Woldorff,
MG},
Title = {The influence of imagery vividness and internally-directed
attention on the neural mechanisms underlying the encoding
of visual mental images into episodic memory.},
Journal = {Cereb Cortex},
Volume = {33},
Number = {6},
Pages = {3207-3220},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1093/cercor/bhac270},
Abstract = {Attention can be directed externally toward sensory
information or internally toward self-generated information.
Using electroencephalography (EEG), we investigated the
attentional processes underlying the formation and encoding
of self-generated mental images into episodic memory.
Participants viewed flickering words referring to common
objects and were tasked with forming visual mental images of
the objects and rating their vividness. Subsequent memory
for the presented object words was assessed using an old-new
recognition task. Internally-directed attention during image
generation was indexed as a reduction in steady-state visual
evoked potentials (SSVEPs), oscillatory EEG responses at the
frequency of a flickering stimulus. The results yielded 3
main findings. First, SSVEP power driven by the flickering
word stimuli decreased as subjects directed attention
internally to form the corresponding mental image. Second,
SSVEP power returned to pre-imagery baseline more slowly for
low- than high-vividness later remembered items, suggesting
that longer internally-directed attention is required to
generate subsequently remembered low-vividness images.
Finally, the event-related-potential difference due to
memory was more sustained for subsequently remembered low-
versus high-vividness items, suggesting that additional
conceptual processing may have been needed to remember the
low-vividness visual images. Taken together, the results
clarify the neural mechanisms supporting the encoding of
self-generated information.},
Doi = {10.1093/cercor/bhac270},
Key = {fds365720}
}
@article{fds362514,
Author = {Becker, M and Cabeza, R},
Title = {Assessing creativity independently of language: A
language-independent remote associate task
(LI-RAT).},
Journal = {Behavior research methods},
Volume = {55},
Number = {1},
Pages = {85-102},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.3758/s13428-021-01773-5},
Abstract = {Most creativity measures are either complex or
language-dependent, hindering cross-cultural creativity
assessment. We have therefore developed and tested a simple,
language-independent insight task based on pictures in the
style of the widely used verbal remote associate task (RAT).
We demonstrate that the language-independent RAT (LI-RAT)
allows assessment of different aspects of insight across
large samples with different languages. It also correlates
with other creativity and general problem-solving tasks. The
entire stimulus set, including its preliminary normative
data, is made freely available. This information can be used
to select items based on accuracy, mean solution time,
likelihood to produce an insight, or conceptual and
perceptual similarity between the pictures per
item.},
Doi = {10.3758/s13428-021-01773-5},
Key = {fds362514}
}
@misc{fds373394,
Author = {Becker, M and Cabeza, R and Kizilirmak, JM},
Title = {A COGNITIVE NEUROSCIENCE PERSPECTIVE ON INSIGHT AS A MEMORY
PROCESS: Searching for the Solution},
Pages = {491-510},
Booktitle = {The Routledge International Handbook of Creative
Cognition},
Year = {2023},
Month = {January},
ISBN = {9780367443788},
url = {http://dx.doi.org/10.4324/9781003009351-31},
Abstract = {What are the cognitive and brain processes that lead to an
insight? In this chapter, we will describe the
insight-solution process from a neurocognitive perspective.
Inspired by cognitive theories, we translate some of
insight’s main cognitive subprocesses (problem
representation, search, representational change and
solution) into related neurocognitive ones and summarize
them in a descriptive framework. Those described processes
focus primarily on verbal insight and are explained using
the remote associates task. In this task, the solver is
provided with several problem elements (e.g., drop, coat and
summer) and needs to find the (remotely related) target that
matches those cues (e.g., rain). In a nutshell, insight is
the consequence of a problem-solving process where the
target is encoded in long-term memory but cannot be
retrieved at first because the relationship between the
problem elements and the target is unknown, precluding a
simple memory search. Upon problem display, the problem
elements and a whole network of associated concepts are
automatically activated in long-term memory in distinct
areas of the brain that represent those concepts (=problem
representation). Insight is assumed to occur when automatic
processes suddenly activate the target after control
processes associated with inferior frontal gyrus (IFG) and
anterior cingulate cortex (ACC) activation manage to
overcome prior knowledge and/or perceptual constraints by
revising the current activation pattern (=representational
change).},
Doi = {10.4324/9781003009351-31},
Key = {fds373394}
}
%% Camacho, Nicolas
@article{fds372783,
Author = {Heaton, KG and Camacho, NL and Gaffrey, MS},
Title = {Associations between pre-pandemic authoritative parenting,
pandemic stressors, and children's depression and anxiety at
the initial stage of the COVID-19 pandemic.},
Journal = {Scientific reports},
Volume = {13},
Number = {1},
Pages = {15592},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1038/s41598-023-42268-x},
Abstract = {Large-scale changes due to the Novel Coronavirus (COVID-19)
pandemic negatively affected children's mental health. Prior
research suggests that children's mental health problems
during the pandemic may have been concurrently attenuated by
an authoritative parenting style and exacerbated by family
stress. However, there is a gap in the literature
investigating these mechanisms and whether pre-pandemic
authoritative parenting had a lasting positive influence on
children's mental health while they were exposed to
pandemic-related family stressors. The current study begins
to fill this gap by investigating these unique relationships
in a sample of 106 4-8 year old children (51% female).
Before the pandemic, caregivers completed questionnaires on
their parenting style and their children's depression and
anxiety symptoms. Shortly after the onset of COVID-19's
stay-at-home mandate, parents answered questionnaires about
their children's depression and anxiety symptoms and
pandemic-related family stressors. Child depression and
anxiety symptom severity increased. Higher levels of
pandemic-related family stress were associated with
increases only in child anxiety scores. Further, greater
endorsement of a pre-pandemic authoritative parenting style
was associated with smaller changes only in child depression
scores. Study findings elucidate unique and complex
associations between young children's anxiety and depression
symptoms severity and pre-pandemic parenting and
pandemic-related family stressors.},
Doi = {10.1038/s41598-023-42268-x},
Key = {fds372783}
}
@article{fds372784,
Author = {Fowler, CH and Bagdasarov, A and Camacho, NL and Reuben, A and Gaffrey,
MS},
Title = {Toxicant exposure and the developing brain: A systematic
review of the structural and functional MRI
literature.},
Journal = {Neuroscience and biobehavioral reviews},
Volume = {144},
Pages = {105006},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1016/j.neubiorev.2022.105006},
Abstract = {Youth worldwide are regularly exposed to pollutants and
chemicals (i.e., toxicants) that may interfere with healthy
brain development, and a surge in MRI research has begun to
characterize the neurobiological consequences of these
exposures. Here, a systematic review following PRISMA
guidelines was conducted on developmental MRI studies of
toxicants with known or suspected neurobiological impact.
Associations were reviewed for 9 toxicant classes, including
metals, air pollution, and flame retardants. Of 1264
identified studies, 46 met inclusion criteria. Qualitative
synthesis revealed that most studies: (1) investigated air
pollutants or metals, (2) assessed exposures prenatally, (3)
assessed the brain in late middle childhood, (4) took place
in North America or Western Europe, (5) drew samples from
existing cohort studies, and (6) have been published since
2017. Given substantial heterogeneity in MRI measures,
toxicant measures, and age groups assessed, more research is
needed on all toxicants reviewed here. Future studies should
also include larger samples, employ personal exposure
monitoring, study independent samples in diverse world
regions, and assess toxicant mixtures.},
Doi = {10.1016/j.neubiorev.2022.105006},
Key = {fds372784}
}
%% Carmody, Karen A.
@article{fds372850,
Author = {Appleyard Carmody and K and Murray, KJ and Williams, B and Frost, A and Coleman, C and Sullivan, K},
Title = {Enhancing early parenting in the community: Preliminary
results from a learning collaborative approach to scale up
Attachment and Biobehavioral Catch-up.},
Journal = {Infant Ment Health J},
Volume = {44},
Number = {6},
Pages = {752-766},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1002/imhj.22081},
Abstract = {Attachment and Biobehavioral Catch-up (ABC) is a promising
home-visiting intervention promoting sensitive caregiving
and secure parent-child attachment in families with young
children. The goal of this study was to examine a learning
collaborative approach to disseminating ABC in a community
setting. Training outcomes (e.g., trainee completion,
satisfaction, effectiveness of training methods) and
intervention outcomes (e.g., parent behavior, parent
beliefs, child socioemotional development) were examined.
Eighteen practitioners participated in the ABC learning
collaborative; 13 completed training. Quantitative and
qualitative measures indicated that trainees were satisfied
with their experience and valued the unique collaboration
opportunities offered by the learning collaborative. In
addition, trainees served 67 families in the community, 37
of whom completed all sessions of ABC. The study was
conducted in the United States. Racial demographics of the
children in the sample included: 56.7% White, 22.4%
Black/African-American, 17.9% Bi- or Multi-racial, and 3.0%
unknown. Regarding ethnicity, 80.6% were
Non-Hispanic/Latino, 10.4% were Hispanic/Latino, and 9.0%
were unknown. Caregivers who completed ABC showed more
sensitive parenting behavior and reported positive changes
in their perceived self-efficacy and their beliefs around
infant crying. Children who received ABC showed increased
socioemotional functioning. Results demonstrate successful
dissemination of ABC in the community using a learning
collaborative approach.},
Doi = {10.1002/imhj.22081},
Key = {fds372850}
}
%% Caspi, Avshalom
@article{fds376907,
Author = {Theadom, A and Barker-Collo, S and Parag, V and Caspi, A and Moffitt,
TE and Hogan, S and Ramrakha, S and Poulton, R},
Title = {Mild Traumatic Brain Injury Does Not Significantly Affect
Midlife Cognitive Functioning Within the General Population:
Findings From a Prospective Longitudinal Birth Cohort
Study.},
Journal = {The Journal of head trauma rehabilitation},
Volume = {39},
Number = {2},
Pages = {E70-E82},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1097/htr.0000000000000875},
Abstract = {<h4>Objective</h4>To determine whether differences exist in
mid-adulthood cognitive functioning in people with and
without history of mild traumatic brain injury
(mTBI).<h4>Setting</h4>Community-based study.<h4>Participants</h4>People
born between April 1, 1972, and March 31, 1973, recruited
into the Dunedin Multidisciplinary Health and Development
Longitudinal Study, who completed neuropsychological
assessments in mid-adulthood. Participants who had
experienced a moderate or severe TBI or mTBI in the past 12
months were excluded.<h4>Design</h4>Longitudinal,
prospective, observational study.<h4>Main measures</h4>Data
were collected on sociodemographic characteristics, medical
history, childhood cognition (between 7 and 11 years), and
alcohol and substance dependence (from 21 years of age).
mTBI history was determined from accident and medical
records (from birth to 45 years of age). Participants were
classified as having 1 mTBI and more in their lifetime or no
mTBI. The Wechsler Adult Intelligence Scale (WAIS-IV) and
Trail Making Tests A and B (between 38 and 45 years of age)
were used to assess cognitive functioning. T tests and
effect sizes were used to identify any differences on
cognitive functioning domains between the mTBI and no mTBI
groups. Regression models explored the relative contribution
of number of mTBIs and age of first mTBI and
sociodemographic/lifestyle variables on cognitive
functioning.<h4>Results</h4>Of the 885 participants, 518
(58.5%) had experienced at least 1 mTBI over their lifetime,
with a mean number of 2.5 mTBIs. The mTBI group had
significantly slower processing speed ( P < .01, d = 0.23)
in mid-adulthood than the no TBI controls, with a medium
effect size. However, the relationship no longer remained
significant after controlling for childhood cognition,
sociodemographic and lifestyle factors. No significant
differences were observed for overall intelligence, verbal
comprehension, perceptual reasoning, working memory,
attention, or cognitive flexibility. Childhood cognition was
not linked to likelihood of sustaining mTBI later in
life.<h4>Conclusion</h4>mTBI histories in the general
population were not associated with lower cognitive
functioning in mid-adulthood once sociodemographic and
lifestyle factors were taken into account.},
Doi = {10.1097/htr.0000000000000875},
Key = {fds376907}
}
@article{fds375234,
Author = {Bourassa, KJ and Garrett, ME and Caspi, A and Dennis, M and Hall, KS and Moffitt, TE and Taylor, GA and VA Mid Atlantic MIRECC Workgroup, and Ashley-Koch, AE and Beckham, JC and Kimbrel, NA},
Title = {Posttraumatic stress disorder, trauma, and accelerated
biological aging among post-9/11 veterans.},
Journal = {Transl Psychiatry},
Volume = {14},
Number = {1},
Pages = {4},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1038/s41398-023-02704-y},
Abstract = {People who experience trauma and develop posttraumatic
stress disorder (PTSD) are at increased risk for poor
health. One mechanism that could explain this risk is
accelerated biological aging, which is associated with the
accumulation of chronic diseases, disability, and premature
mortality. Using data from 2309 post-9/11 United States
military veterans who participated in the VISN 6 MIRECC's
Post-Deployment Mental Health Study, we tested whether PTSD
and trauma exposure were associated with accelerated rate of
biological aging, assessed using a validated DNA methylation
(DNAm) measure of epigenetic aging-DunedinPACE. Veterans
with current PTSD were aging faster than those who did not
have current PTSD, β = 0.18, 95% CI [0.11, 0.27],
p < .001. This effect represented an additional 0.4
months of biological aging each year. Veterans were also
aging faster if they reported more PTSD symptoms,
β = 0.13, 95% CI [0.09, 0.16], p < 0.001, or higher
levels of trauma exposure, β = 0.09, 95% CI [0.05,
0.13], p < 0.001. Notably, veterans with past PTSD were
aging more slowly than those with current PTSD,
β = -0.21, 95% CI [-0.35, -0.07], p = .003. All
reported results accounted for age, gender, self-reported
race/ethnicity, and education, and remained when controlling
for smoking. Our findings suggest that an accelerated rate
of biological aging could help explain how PTSD contributes
to poor health and highlights the potential benefits of
providing efficacious treatment to populations at increased
risk of trauma and PTSD.},
Doi = {10.1038/s41398-023-02704-y},
Key = {fds375234}
}
@article{fds370625,
Author = {Caspi, A and Houts, RM and Fisher, HL and Danese, A and Moffitt,
TE},
Title = {The general factor of psychopathology (p): Choosing among
competing models and interpreting p.},
Journal = {Clinical psychological science : a journal of the
Association for Psychological Science},
Volume = {12},
Number = {1},
Pages = {53-82},
Publisher = {SAGE Publications},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1177/21677026221147872},
Abstract = {Over the past 10 years, the general factor of
psychopathology, p, has attracted interest and scrutiny. We
review the history of the idea that all mental disorders
share something in common, p; how we arrived at this idea;
and how it became conflated with a statistical
representation, the Bi-Factor Model. We then leverage the
Environmental Risk (E-Risk) longitudinal twin study to
examine the properties and nomological network of different
statistical representations of p. We find that p performed
similarly regardless of how it was modelled, suggesting that
if the sample and content are the same the resulting p
factor will be similar. We suggest that the meaning of p is
not to be found by dueling over statistical models but by
conducting well-specified criterion-validation studies and
developing new measurement approaches. We outline new
directions to refresh research efforts to uncover what all
mental disorders have in common.},
Doi = {10.1177/21677026221147872},
Key = {fds370625}
}
@article{fds375233,
Author = {Brennan, GM and Moffitt, TE and Bourassa, KJ and Harrington, HL and Hogan, S and Houts, RM and Poulton, R and Ramrakha, S and Caspi,
A},
Title = {The Continuity of Adversity: Negative Emotionality Links
Early Life Adversity With Adult Stressful Life
Events},
Journal = {Clinical Psychological Science},
Publisher = {SAGE Publications},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1177/21677026231220337},
Abstract = {Adversity that exhibits continuity across the life course
has long-term detrimental effects on physical and mental
health. Using 920 participants from the Dunedin Study, we
tested the following hypotheses: (a) Children (ages 3–15)
who experienced adversity would also tend to experience
adversity in adulthood (ages 32–45), and (2) interim
personality traits in young adulthood (ages 18–26) would
help account for this longitudinal association. Children who
experienced more adversity tended to also experience more
stressful life events as adults, β = 0.11, 95% confidence
interval [CI] = [0.04, 0.18], p =.002. Negative
emotionality—particularly its subfacet alienation,
characterized by mistrust of others—helped explain this
childhood-to-midlife association (indirect effect: β =
0.06, 95% CI = [0.04, 0.09], p <.001). Results were robust
to adjustment for sex, socioeconomic origins, childhood IQ,
preschool temperament, and other young-adult personality
traits. Prevention of early life adversity and treatment of
young-adult negative emotionality may reduce vulnerability
to later life stress and thereby promote the health of aging
adults.},
Doi = {10.1177/21677026231220337},
Key = {fds375233}
}
@article{fds373507,
Author = {Knodt, AR and Elliott, ML and Whitman, ET and Winn, A and Addae, A and Ireland, D and Poulton, R and Ramrakha, S and Caspi, A and Moffitt, TE and Hariri, AR},
Title = {Test-retest reliability and predictive utility of a
macroscale principal functional connectivity
gradient.},
Journal = {Human brain mapping},
Volume = {44},
Number = {18},
Pages = {6399-6417},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1002/hbm.26517},
Abstract = {Mapping individual differences in brain function has been
hampered by poor reliability as well as limited
interpretability. Leveraging patterns of brain-wide
functional connectivity (FC) offers some promise in this
endeavor. In particular, a macroscale principal FC gradient
that recapitulates a hierarchical organization spanning
molecular, cellular, and circuit level features along a
sensory-to-association cortical axis has emerged as both a
parsimonious and interpretable measure of individual
differences in behavior. However, the measurement
reliabilities of this FC gradient have not been fully
evaluated. Here, we assess the reliabilities of both global
and regional principal FC gradient measures using
test-retest data from the young adult Human Connectome
Project (HCP-YA) and the Dunedin Study. Analyses revealed
that the reliabilities of principal FC gradient measures
were (1) consistently higher than those for traditional
edge-wise FC measures, (2) higher for FC measures derived
from general FC (GFC) in comparison with resting-state FC,
and (3) higher for longer scan lengths. We additionally
examined the relative utility of these principal FC gradient
measures in predicting cognition and aging in both datasets
as well as the HCP-aging dataset. These analyses revealed
that regional FC gradient measures and global gradient range
were significantly associated with aging in all three
datasets, and moderately associated with cognition in the
HCP-YA and Dunedin Study datasets, reflecting contractions
and expansions of the cortical hierarchy, respectively.
Collectively, these results demonstrate that measures of the
principal FC gradient, especially derived using GFC,
effectively capture a reliable feature of the human brain
subject to interpretable and biologically meaningful
individual variation, offering some advantages over
traditional edge-wise FC measures in the search for
brain-behavior associations.},
Doi = {10.1002/hbm.26517},
Key = {fds373507}
}
@article{fds373927,
Author = {Synergy for the Influence of the Month of Birth in ADHD
(SIMBA) study group},
Title = {Association between relative age at school and persistence
of ADHD in prospective studies: an individual participant
data meta-analysis.},
Journal = {Lancet Psychiatry},
Volume = {10},
Number = {12},
Pages = {922-933},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1016/S2215-0366(23)00272-9},
Abstract = {BACKGROUND: The youngest children in a school class are more
likely than the oldest to be diagnosed with ADHD, but this
relative age effect is less frequent in older than in
younger school-grade children. However, no study has
explored the association between relative age and the
persistence of ADHD diagnosis at older ages. We aimed to
quantify the association between relative age and
persistence of ADHD at older ages. METHODS: For this
meta-analysis, we searched MEDLINE, Embase, CINAHL,
PsycINFO, and PubPsych up to April 1, 2022, with terms
related to "cohort" and "ADHD" with no date, publication
type, or language restrictions. We gathered individual
participant data from prospective cohorts that included at
least ten children identified with ADHD before age 10 years.
ADHD was defined by either a clinical diagnosis or symptoms
exceeding clinical cutoffs. Relative age was recorded as the
month of birth in relation to the school-entry cutoff date.
Study authors were invited to share raw data or to apply a
script to analyse data locally and generate anonymised
results. Our outcome was ADHD status at a diagnostic
reassessment, conducted at least 4 years after the initial
assessment and after age 10 years. No information on sex,
gender, or ethnicity was collected. We did a two-stage
random-effects individual participant data meta-analysis to
assess the association of relative age with persistence of
ADHD at follow-up. This study was registered with PROSPERO,
CRD42020212650. FINDINGS: Of 33 119 studies generated by
our search, we identified 130 eligible unique studies and
were able to gather individual participant data from 57
prospective studies following up 6504 children with ADHD.
After exclusion of 16 studies in regions with a flexible
school entry system that did not allow confident linkage of
birthdate to relative age, the primary analysis included 41
studies in 15 countries following up 4708 children for a
period of 4 to 33 years. We found that younger relative age
was not statistically significantly associated with ADHD
persistence at follow-up (odds ratio 1·02, 95% CI
0·99-1·06; p=0·19). We observed statistically significant
heterogeneity in our model (Q=75·82, p=0·0011, I2=45%).
Participant-level sensitivity analyses showed similar
results in cohorts with a robust relative age effect at
baseline and when restricting to cohorts involving children
with a clinical diagnosis of ADHD or with a follow-up
duration of more than 10 years. INTERPRETATION: The
diagnosis of ADHD in younger children in a class is no more
likely to be disconfirmed over time than that of older
children in the class. One interpretation is that the
relative age effect decreases the likelihood of children of
older relative age receiving a diagnosis of ADHD, and
another is that assigning a diagnostic label of ADHD leads
to unexplored carryover effects of the initial diagnosis
that persist over time. Future studies should be conducted
to explore these interpretations further. FUNDING:
None.},
Doi = {10.1016/S2215-0366(23)00272-9},
Key = {fds373927}
}
@article{fds375276,
Author = {Brennan, GM and Moffitt, TE and Ambler, A and Harrington, H and Hogan,
S and Houts, RM and Mani, R and Poulton, R and Ramrakha, S and Caspi,
A},
Title = {Tracing the origins of midlife despair: association of
psychopathology during adolescence with a syndrome of
despair-related maladies at midlife.},
Journal = {Psychological medicine},
Volume = {53},
Number = {16},
Pages = {7569-7580},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1017/s0033291723001320},
Abstract = {<h4>Background</h4>Midlife adults are experiencing a crisis
of deaths of despair (i.e. deaths from suicide, drug
overdose, and alcohol-related liver disease). We tested the
hypothesis that a syndrome of despair-related maladies at
midlife is preceded by psychopathology during
adolescence.<h4>Methods</h4>Participants are members of a
representative cohort of 1037 individuals born in Dunedin,
New Zealand in 1972-73 and followed to age 45 years, with
94% retention. Adolescent mental disorders were assessed in
three diagnostic assessments at ages 11, 13, and 15 years.
Indicators of despair-related maladies across four domains -
suicidality, substance misuse, sleep problems, and pain -
were assessed at age 45 using multi-modal measures including
self-report, informant-report, and national register
data.<h4>Results</h4>We identified and validated a syndrome
of despair-related maladies at midlife involving
suicidality, substance misuse, sleep problems, and pain.
Adults who exhibited a more severe syndrome of
despair-related maladies at midlife tended to have had
early-onset emotional and behavioral disorders [<i>β</i> =
0.23, 95% CI (0.16-0.30), <i>p</i> < 0.001], even after
adjusting for sex, childhood SES, and childhood IQ. A more
pronounced midlife despair syndrome was observed among
adults who, as adolescents, were diagnosed with a greater
number of mental disorders [<i>β</i> = 0.26, 95% CI
(0.19-0.33), <i>p</i> < 0.001]. Tests of diagnostic
specificity revealed that associations generalized across
different adolescent mental disorders.<h4>Conclusions</h4>Midlife
adults who exhibited a more severe syndrome of
despair-related maladies tended to have had psychopathology
as adolescents. Prevention and treatment of adolescent
psychopathology may mitigate despair-related maladies at
midlife and ultimately reduce deaths of despair.},
Doi = {10.1017/s0033291723001320},
Key = {fds375276}
}
@article{fds371465,
Author = {Røysamb, E and Moffitt, TE and Caspi, A and Ystrøm, E and Nes,
RB},
Title = {Worldwide Well-Being: Simulated Twins Reveal Genetic and
(Hidden) Environmental Influences.},
Journal = {Perspectives on psychological science : a journal of the
Association for Psychological Science},
Volume = {18},
Number = {6},
Pages = {1562-1574},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1177/17456916231178716},
Abstract = {What are the major sources of worldwide variability in
subjective well-being (SWB)? Twin and family studies of SWB
have found substantial heritability and strong effects from
unique environments but virtually no effects from shared
environments. However, extant findings are not necessarily
valid at the global level. Prior studies have examined
within-countries variability but did not take into account
mean differences across nations. In this article, we aim to
estimate the effects of genetic factors, individual
environmental exposures, and shared environments for the
global population. We combine a set of knowns from national
well-being studies (means and standard deviations) and
behavioral-genetic studies (heritability) to model a
scenario of twin studies across 157 countries. For each
country, we simulate data for a set of twin pairs and pool
the data into a global sample. We find a worldwide
heritability of 31% to 32% for SWB. Individual environmental
factors explain 46% to 52% of the variance (including
measurement error), and shared environments account for 16%
to 23% of the global variance in SWB. Worldwide, well-being
is somewhat less heritable than within nations. In contrast
to previous within-countries studies, we find a notable
effect of shared environments. This effect is not limited to
within families but operates at a national
level.},
Doi = {10.1177/17456916231178716},
Key = {fds371465}
}
@article{fds373926,
Author = {Caspi, A and Shireby, G and Mill, J and Moffitt, TE and Sugden, K and Hannon, E},
Title = {Accelerated Pace of Aging in Schizophrenia: Five
Case-Control Studies.},
Journal = {Biological psychiatry},
Pages = {S0006-3223(23)01693-1},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1016/j.biopsych.2023.10.023},
Abstract = {<h4>Background</h4>Schizophrenia is associated with
increased risk of developing multiple aging-related
diseases, including metabolic, respiratory, and
cardiovascular diseases, and Alzheimer's and related
dementias, leading to the hypothesis that schizophrenia is
accompanied by accelerated biological aging. This has been
difficult to test because there is no widely accepted
measure of biological aging. Epigenetic clocks are promising
algorithms that are used to calculate biological age on the
basis of information from combined cytosine-phosphate-guanine
sites (CpGs) across the genome, but they have yielded
inconsistent and often negative results about the
association between schizophrenia and accelerated aging.
Here, we tested the schizophrenia-aging hypothesis using a
DNA methylation measure that is uniquely designed to predict
an individual's rate of aging.<h4>Methods</h4>We brought
together 5 case-control datasets to calculate DunedinPACE
(Pace of Aging Calculated from the Epigenome), a new measure
trained on longitudinal data to detect differences between
people in their pace of aging over time. Data were available
from 1812 psychosis cases (schizophrenia or first-episode
psychosis) and 1753 controls. Mean chronological age was
38.9 (SD = 13.6) years.<h4>Results</h4>We observed
consistent associations across datasets between
schizophrenia and accelerated aging as measured by
DunedinPACE. These associations were not attributable to
tobacco smoking or clozapine medication.<h4>Conclusions</h4>Schizophrenia
is accompanied by accelerated biological aging by midlife.
This may explain the wide-ranging risk among people with
schizophrenia for developing multiple different age-related
physical diseases, including metabolic, respiratory, and
cardiovascular diseases, and dementia. Measures of
biological aging could prove valuable for assessing
patients' risk for physical and cognitive decline and for
evaluating intervention effectiveness.},
Doi = {10.1016/j.biopsych.2023.10.023},
Key = {fds373926}
}
@article{fds367655,
Author = {Conway, CC and Kotov, R and Krueger, RF and Caspi,
A},
Title = {Translating the hierarchical taxonomy of psychopathology
(HiTOP) from potential to practice: Ten research
questions.},
Journal = {The American psychologist},
Volume = {78},
Number = {7},
Pages = {873-885},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1037/amp0001046},
Abstract = {The Hierarchical Taxonomy of Psychopathology (HiTOP) is a
novel diagnostic system grounded in empirical research into
the architecture of mental illness. Its basic units are
continuous dimensions-as opposed to categories-that are
organized into a hierarchy according to patterns of symptom
co-occurrence observed in quantitative studies. Previous
HiTOP discussions have focused on existing evidence
regarding the model's structure and ability to account for
neurobiological, social, cultural, and clinical variation.
The present article looks ahead to the next decade of
applied research and clinical practice using the HiTOP
rubric. We highlight 10 topics where HiTOP has the potential
to make significant breakthroughs. Research areas include
genetic influences, environmental contributions, neural
mechanisms, real-time dynamics, and lifespan development of
psychopathology. We also discuss development of novel
assessments, forecasting methods, and treatments. Finally,
we consider implications for clinicians and educators. For
each of these domains, we propose directions for future
research and venture hypotheses as to what HiTOP will reveal
about psychopathology. (PsycInfo Database Record (c) 2023
APA, all rights reserved).},
Doi = {10.1037/amp0001046},
Key = {fds367655}
}
@article{fds373558,
Author = {Kessing, LV and Ziersen, SC and Caspi, A and Moffitt, TE and Andersen,
PK},
Title = {Lifetime Incidence of Treated Mental Health Disorders and
Psychotropic Drug Prescriptions and Associated Socioeconomic
Functioning.},
Journal = {JAMA psychiatry},
Volume = {80},
Number = {10},
Pages = {1000-1008},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1001/jamapsychiatry.2023.2206},
Abstract = {<h4>Importance</h4>Few studies have estimated the lifetime
incidence of mental health disorders and the association
with socioeconomic functioning.<h4>Objective</h4>To
investigate whether the lifetime incidence of treated mental
health disorders is substantially higher than previously
reported and estimate associations with long-term
socioeconomic difficulties.<h4>Design, setting, and
participants</h4>This nationwide population-based register
linkage study includes a randomly selected sample of 1.5
million individuals from the population of Denmark from 1995
to 2018. Data were analyzed from May 2022 to March
2023.<h4>Main outcomes and measures</h4>Lifetime incidence
of any treated mental health disorder in the general
population was estimated from birth to age 100 years taking
into account the competing risk of all-cause death and
associations with socioeconomic functioning. Register
measures were (1) from hospitals, a diagnosis of any mental
health disorder at an inpatient/outpatient hospital contact;
(2) from hospitals and prescription statistics, any mental
health disorder/psychotropic prescription, including a
hospital-contact diagnosis, or any psychotropic medication
prescribed by physicians, including general practitioners or
private psychiatrists; and (3) socioeconomic functioning as
indicated by highest educational achievement, employment,
income, residential status, and marital status.<h4>Results</h4>Among
a sample of 462 864 individuals with any mental health
disorder, the median (IQR) age was 36.6 years (21.0-53.6
years), 233 747 (50.5%) were male, and 229 117 (49.5%)
were female. Of these, 112 641 were registered with a
hospital-contact mental health disorder diagnosis and
422 080 with a prescription of psychotropic medication.
The cumulative incidence of a hospital-contact mental health
disorder diagnosis was 29.0% (95% CI, 28.8-29.1), 31.8% (95%
CI, 31.6-32.0) for females, and 26.1% (95% CI, 25.9-26.3)
for males. When also considering psychotropic prescriptions,
the cumulative incidence of any mental health
disorder/psychotropic prescription was 82.6% (95% CI,
82.4-82.6), 87.5% (95% CI, 87.4-87.7) for females, and 76.7%
(95% CI, 76.5-76.8) for males. Socioeconomic difficulties
were associated with mental health disorder/psychotropic
prescriptions, including lower income (hazard ratio [HR],
1.55; 95% CI, 1.53-1.56), increased unemployment or
disability benefit (HR, 2.50; 95% CI, 2.47-2.53), and a
greater likelihood of living alone (HR, 1.78; 95% CI,
1.76-1.80) and being unmarried (HR, 2.02; 95% CI, 2.01-2.04)
during long-term follow-up. These rates were confirmed in 4
sensitivity analyses with the lowest being 74.8% (95% CI,
74.7-75.0) (1) by using varying exclusion periods, (2) by
excluding prescriptions of anxiolytics and quetiapine that
may be used for off-label indications, (3) by defining any
mental health disorder/psychotropic prescription as any
hospital-contact mental health disorder diagnosis or any
psychotropic medication prescribed at least 2 times, and (4)
by excluding individuals with somatic diagnoses for which
psychotropics may be prescribed off-label.<h4>Conclusions
and relevance</h4>This registry study of data from a large
representative sample of the Danish population showed that
the majority of individuals either received a diagnosis of a
mental health disorder or were prescribed psychotropic
medication during their lifetime, which was associated with
subsequent socioeconomic difficulties. These findings may
help change our understanding of normalcy and mental
illness, reduce stigmatization, and further prompt
rethinking the primary prevention of mental illness and
future mental health clinical resources.},
Doi = {10.1001/jamapsychiatry.2023.2206},
Key = {fds373558}
}
@article{fds372970,
Author = {Slutske, WS and Richmond-Rakerd, LS and Piasecki, TM and Ramrakha, S and Poulton, R and Moffitt, TE and Caspi, A},
Title = {Disordered gambling in a longitudinal birth cohort: from
childhood precursors to adult life outcomes.},
Journal = {Psychological medicine},
Volume = {53},
Number = {12},
Pages = {5800-5808},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1017/s0033291722003051},
Abstract = {<h4>Background</h4>Despite its introduction into the
diagnostic nomenclature over four decades ago, there remain
large knowledge gaps about disordered gambling. The primary
aims of the present study were to document the long-term
course, childhood precursors, and adult life outcomes
associated with disordered gambling.<h4>Methods</h4>Participants
enrolled in the population-representative Dunedin Study were
prospectively followed from birth through age 45. Disordered
gambling was assessed six times from age 18; composite
measures of childhood social class, general intelligence,
and low self-control were based on assessments obtained from
birth through age 15; adult socioeconomic, financial, and
legal outcomes were obtained through age 45. Lifetime
disordered gambling was predicted from the three childhood
precursors and the adult outcomes were predicted from
lifetime disordered gambling.<h4>Results</h4>Past-year
disordered gambling usually occurred at only a single time
point and recurrence was relatively uncommon. Lower
childhood social class, general intelligence, and
self-control significantly predicted lifetime disordered
gambling in adulthood. In turn, lifetime disordered gambling
in adulthood significantly predicted occupational,
educational, and financial problems in adulthood (<i>ds</i>
= 0.23-0.41). These associations were markedly reduced and
sometimes rendered nonsignificant after adjusting for
childhood precursors (<i>ds</i> = 0.04-0.32).<h4>Conclusions</h4>Socioeconomic,
financial, and legal outcomes in adulthood are not merely
consequences of disordered gambling, but also are predicted
from childhood precursors. Deflecting the trajectories of
young people at risk for developing disordered gambling may
help to ameliorate not just the development of later
disordered gambling, but also other associated adverse
outcomes.},
Doi = {10.1017/s0033291722003051},
Key = {fds372970}
}
@article{fds373925,
Author = {Ruiz, B and Broadbent, JM and Thomson, WM and Ramrakha, S and Moffitt,
TE and Caspi, A and Poulton, R},
Title = {Childhood caries is associated with poor health and a faster
pace of aging by midlife.},
Journal = {Journal of public health dentistry},
Volume = {83},
Number = {4},
Pages = {381-388},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1111/jphd.12591},
Abstract = {<h4>Objectives</h4>Childhood caries is associated with
poorer self-rated general health in adulthood, but it
remains unclear whether that holds for physical health and
aging. The aim of this study was to identify whether age-5
caries is associated with (a) biomarkers for poor physical
health, and (b) the pace of aging (PoA) by age
45 years.<h4>Methods</h4>Participants are members of the
Dunedin Multidisciplinary Health and Development Study birth
cohort. At age 45, 94.1% (n = 938) of those still alive
took part. Data on age-5 caries experience and age-45 health
biomarkers were collected. The PoA captures age-related
decline across the cardiovascular, metabolic, renal, immune,
dental and pulmonary systems from age 26 to 45 years. We
used (a) generalized estimating equations to examine
associations between age-5 caries and poor physical health
by age 45 years, and (b) ordinary least squares regression
to examine whether age-5 caries was associated with the PoA.
Analyses adjusted for sex, perinatal health, childhood SES
and childhood IQ.<h4>Results</h4>High caries experience at
age-5 was associated with higher risk for some metabolic
abnormalities, including BMI ≥30, high waist
circumference, and high serum leptin. Those with high caries
experience at age-5 were aging at a faster rate by age
45 years than those who had been caries-free.<h4>Conclusions</h4>Oral
health is essential for wellbeing. Poor oral health can be
an early signal of a trajectory towards poor health in
adulthood. Management for both conditions should be
better-integrated; and integrated population-level
prevention strategies should be foundational to any health
system.},
Doi = {10.1111/jphd.12591},
Key = {fds373925}
}
@article{fds370242,
Author = {Sugden, K and Moffitt, TE and Arpawong, TE and Arseneault, L and Belsky,
DW and Corcoran, DL and Crimmins, EM and Hannon, E and Houts, R and Mill,
JS and Poulton, R and Ramrakha, S and Wertz, J and Williams, BS and Caspi,
A},
Title = {Cross-National and Cross-Generational Evidence That
Educational Attainment May Slow the Pace of Aging in
European-Descent Individuals.},
Journal = {The journals of gerontology. Series B, Psychological
sciences and social sciences},
Volume = {78},
Number = {8},
Pages = {1375-1385},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1093/geronb/gbad056},
Abstract = {<h4>Objectives</h4>Individuals with more education are at
lower risk of developing multiple, different age-related
diseases than their less-educated peers. A reason for this
might be that individuals with more education age slower.
There are 2 complications in testing this hypothesis. First,
there exists no definitive measure of biological aging.
Second, shared genetic factors contribute toward both lower
educational attainment and the development of age-related
diseases. Here, we tested whether the protective effect of
educational attainment was associated with the pace of aging
after accounting for genetic factors.<h4>Methods</h4>We
examined data from 5 studies together totaling almost 17,000
individuals with European ancestry born in different
countries during different historical periods, ranging in
age from 16 to 98 years old. To assess the pace of aging, we
used DunedinPACE, a DNA methylation algorithm that reflects
an individual's rate of aging and predicts age-related
decline and Alzheimer's disease and related disorders. To
assess genetic factors related to education, we created a
polygenic score based on the results of a genome-wide
association study of educational attainment.<h4>Results</h4>Across
the 5 studies, and across the life span, higher educational
attainment was associated with a slower pace of aging even
after accounting for genetic factors (meta-analysis effect
size = -0.20; 95% confidence interval [CI]: -0.30 to -0.10;
p = .006). Further, this effect persisted after taking into
account tobacco smoking (meta-analysis effect size = -0.13;
95% CI: -0.21 to -0.05; p = .01).<h4>Discussion</h4>These
results indicate that higher levels of education have
positive effects on the pace of aging, and that the benefits
can be realized irrespective of individuals'
genetics.},
Doi = {10.1093/geronb/gbad056},
Key = {fds370242}
}
@article{fds371464,
Author = {Wertz, J and Moffitt, TE and Arseneault, L and Barnes, JC and Boivin, M and Corcoran, DL and Danese, A and Hancox, RJ and Harrington, H and Houts,
RM and Langevin, S and Liu, H and Poulton, R and Sugden, K and Tanksley,
PT and Williams, BS and Caspi, A},
Title = {Genetic associations with parental investment from
conception to wealth inheritance in six cohorts.},
Journal = {Nature human behaviour},
Volume = {7},
Number = {8},
Pages = {1388-1401},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1038/s41562-023-01618-5},
Abstract = {Genetic inheritance is not the only way parents' genes may
affect children. It is also possible that parents' genes are
associated with investments into children's development. We
examined evidence for links between parental genetics and
parental investments, from the prenatal period through to
adulthood, using data from six population-based cohorts in
the UK, US and New Zealand, together totalling 36,566
parents. Our findings revealed associations between parental
genetics-summarized in a genome-wide polygenic score-and
parental behaviour across development, from smoking in
pregnancy, breastfeeding in infancy, parenting in childhood
and adolescence, to leaving a wealth inheritance to adult
children. Effect sizes tended to be small at any given time
point, ranging from RR = 1.12 (95% confidence interval
(95%CI) 1.09, 1.15) to RR = 0.76 (95%CI 0.72, 0.80)
during the prenatal period and infancy; β = 0.07 (95%CI
0.04, 0.11) to β = 0.29 (95%CI 0.27, 0.32) in childhood
and adolescence, and RR = 1.04 (95%CI 1.01, 1.06) to
RR = 1.11 (95%CI 1.07, 1.15) in adulthood. There was
evidence for accumulating effects across development,
ranging from β = 0.15 (95%CI 0.11, 0.18) to
β = 0.23 (95%CI 0.16, 0.29) depending on cohort. Our
findings are consistent with the interpretation that parents
pass on advantages to offspring not only via direct genetic
transmission or purely environmental paths, but also via
genetic associations with parental investment from
conception to wealth inheritance.},
Doi = {10.1038/s41562-023-01618-5},
Key = {fds371464}
}
@article{fds366662,
Author = {Bourassa, KJ and Moffitt, TE and Harrington, H and Houts, R and Poulton,
R and Ramrakha, S and Rasmussen, LJH and Wertz, J and Caspi,
A},
Title = {Childhood Adversity and Midlife Health: Shining a Light on
the Black Box of Psychosocial Mechanisms.},
Journal = {Prevention science : the official journal of the Society for
Prevention Research},
Volume = {24},
Number = {5},
Pages = {817-828},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1007/s11121-022-01431-y},
Abstract = {Adverse childhood experiences (ACEs) are associated with
poorer health, which has spurred public health efforts to
reduce the number of adverse events children experience.
Unfortunately, it is unlikely that all ACEs can be
prevented. For adults who already experienced ACEs in
childhood, what psychological, social, and behavioral
intervention targets might reduce risk for negative health
outcomes? To provide insight into the "black box" of
psychosocial mechanisms linking ACEs to poor health, our
study used data from the Dunedin Study, a longitudinal
cohort assessed from birth to age 45. Mediation models
(N = 859) were used to examine whether candidate
psychosocial variables in adulthood explained the
association between childhood ACEs and health in midlife.
Potential psychosocial mediators included stressful life
events, perceived stress, negative emotionality, and health
behaviors. Children who experienced more ACEs had poorer
health in midlife. They also had significantly more
stressful life events, more perceived stress, more negative
emotionality, and unhealthier behaviors as adults. These
mediators were each independently associated with poorer
health in midlife and statistically mediated the association
between ACEs and midlife health. Health behaviors evidenced
the strongest indirect effect from ACEs to midlife health.
Together, these psychosocial mediators accounted for the
association between ACEs in childhood and health three
decades later. Public health efforts to mitigate the health
consequences of ACEs could aim to reduce the stressful life
events people experience, reduce negative emotionality,
reduce perceived stress, or improve health behaviors among
adults who experienced childhood adversity.},
Doi = {10.1007/s11121-022-01431-y},
Key = {fds366662}
}
@article{fds369353,
Author = {Gjerde, LC and Eilertsen, EM and McAdams, TA and Cheesman, R and Moffitt, TE and Caspi, A and Eley, TC and Røysamb, E and Rosenström,
TH and Ystrom, E},
Title = {The p factor of psychopathology and personality in
middle childhood: genetic and gestational risk
factors.},
Journal = {Psychological medicine},
Volume = {53},
Number = {9},
Pages = {4275-4285},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1017/s0033291723000077},
Abstract = {<h4>Background</h4>A joint, hierarchical structure of
psychopathology and personality has been reported in adults
but should also be investigated at earlier ages, as
psychopathology often develops before adulthood. Here, we
investigate the joint factor structure of psychopathology
and personality in eight-year-old children, estimate factor
heritability and explore external validity through
associations with established developmental risk
factors.<h4>Methods</h4>Phenotypic and biometric exploratory
factor analyses with bifactor rotation on genetically
informative data from the Norwegian Mother, Father, and
Child Cohort (MoBa) study. The analytic sub-sample comprised
10 739 children (49% girls). Mothers reported their
children's symptoms of depression (Short Moods and Feelings
Questionnaire), anxiety (Screen for Anxiety Related
Disorders), attention-deficit/hyperactivity disorder
inattention and hyperactivity, oppositional-defiant
disorder, conduct disorder (Parent/Teacher Rating Scale for
Disruptive Behavior Disorders), and Big Five personality
(short Hierarchical Personality Inventory for Children).
Developmental risk factors (early gestational age and being
small for gestational age) were collected from the Medical
Birth Registry.<h4>Results</h4>Goodness-of-fit indices
favored a <i>p</i> factor model with three residual latent
factors interpreted as negative affectivity, positive
affectivity, and antagonism, whereas psychometric indices
favored a one-factor model. ADE solutions fitted best, and
regression analyses indicated a negative association between
gestational age and the <i>p</i> factor, for both the one-
and four-factor solutions.<h4>Conclusion</h4>Correlations
between normative and pathological traits in middle
childhood mostly reflect one heritable and psychometrically
interpretable <i>p</i> factor, although optimal fit to data
required less interpretable residual latent factors. The
association between the <i>p</i> factor and low gestational
age warrants further study of early developmental
mechanisms.},
Doi = {10.1017/s0033291723000077},
Key = {fds369353}
}
@article{fds370626,
Author = {Gjerde, LC and Eilertsen, EM and McAdams, TA and Cheesman, R and Moffitt, TE and Caspi, A and Eley, TC and Røysamb, E and Rosenström,
TH and Ystrom, E},
Title = {The p factor of psychopathology and personality in
middle childhood: Genetic and gestational risk factors -
Corrigendum.},
Journal = {Psychological medicine},
Volume = {53},
Number = {9},
Pages = {4303-4304},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1017/s0033291723000879},
Doi = {10.1017/s0033291723000879},
Key = {fds370626}
}
@article{fds370369,
Author = {Madrid-Valero, JJ and Matthews, T and Barclay, NL and Odgers, CL and Moffitt, TE and Caspi, A and Arseneault, L and Gregory,
AM},
Title = {Problematic technology use and sleep quality in young
adulthood: novel insights from a nationally representative
twin study.},
Journal = {Sleep},
Volume = {46},
Number = {6},
Pages = {zsad038},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1093/sleep/zsad038},
Abstract = {<h4>Study objectives</h4>Digital technology use is
associated with poor sleep quality in adolescence and young
adulthood although research findings have been mixed. No
studies have addressed the association between the two using
a genetically informative twin design which could extend our
understanding of the etiology of this relationship. This
study aimed to test: (1) the association between
adolescents' perceived problematic use of digital technology
and poor sleep quality, (2) whether the association between
problematic use of technology and poor sleep quality remains
after controlling for familial factors, and (3) genetic and
environmental influences on the association between
problematic use of technology and poor sleep
quality.<h4>Methods</h4>Participants were 2232 study members
(18-year-old twins) of the Environmental Risk (E-Risk)
Longitudinal Twin Study. The sample was 48.9% male, 90%
white, and 55.6% monozygotic. We conducted regression and
twin difference analyses and fitted twin
models.<h4>Results</h4>Twin differences for problematic use
of technology were associated with differences for poor
sleep quality in the whole sample (p < 0.001; B = 0.15) and
also when we limited the analyses to identical twins only (p
< 0.001; B = 0.21). We observed a substantial genetic
correlation between problematic use of technology and sleep
quality (rA = 0.31), whereas the environmental correlation
was lower (rE = 0.16).<h4>Conclusions</h4>Adolescent
reported problematic use of digital technology is associated
with poor sleep quality-even after controlling for familial
factors including genetic confounds. Our results suggest
that the association between adolescents' sleep and
problematic digital technology use is not accounted for by
shared genetic liability or familial factors but could
reflect a causal association. This robust association needs
to be examined in future research designed to test causal
associations.},
Doi = {10.1093/sleep/zsad038},
Key = {fds370369}
}
@article{fds371264,
Author = {Bourassa, KJ and Caspi, A and Brennan, GM and Hall, KS and Harrington,
H and Houts, R and Kimbrel, NA and Poulton, R and Ramrakha, S and Taylor,
GA and Moffitt, TE},
Title = {Which Types of Stress Are Associated With Accelerated
Biological Aging? Comparing Perceived Stress, Stressful Life
Events, Childhood Adversity, and Posttraumatic Stress
Disorder.},
Journal = {Psychosom Med},
Volume = {85},
Number = {5},
Pages = {389-396},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1097/PSY.0000000000001197},
Abstract = {OBJECTIVE: Stress and stressful events are associated with
poorer health; however, there are multiple ways to
conceptualize and measure stress and stress responses. One
physiological mechanism through which stress could result in
poorer health is accelerated biological aging. This study
tested which types of stress were associated with
accelerated biological aging in adulthood. METHODS: Studying
955 participants from the Dunedin Longitudinal Study, we
tested whether four types of stress assessed from ages 32 to
45 years-perceived stress, number of stressful life events,
adverse childhood experiences, and posttraumatic stress
disorder-were associated with accelerated biological aging.
RESULTS: Higher levels of all four measures of stress were
significantly associated with accelerated aging in separate
models. In a combined model, more perceived stress and more
stressful life events remained associated with faster aging,
and the stress measures explained 6.9% of the variance in
aging. The magnitudes of the associations between the four
measures of stress and biological aging were comparable to
associations for smoking and low education, two established
risk factors for accelerated aging. People with high levels
of perceived stress, numerous adverse childhood experiences
(4+), high stressful life event counts, or posttraumatic
stress disorder were aging an additional estimated 2.4
months, 1.1 additional months, 1.4 months, and 1.4 months
per year, respectively. CONCLUSIONS: Assessing stress,
particularly perceived stress, could help identify people at
risk of accelerated aging. Intervening to treat stress or
the health-relevant sequelae of stress could potentially
slow the rate at which people are aging, improving their
health as they age.},
Doi = {10.1097/PSY.0000000000001197},
Key = {fds371264}
}
@article{fds371653,
Author = {Whitman, ET and Knodt, AR and Elliott, ML and Abraham, WC and Cheyne, K and Hogan, S and Ireland, D and Keenan, R and Leung, JH and Melzer, TR and Poulton, R and Purdy, SC and Ramrakha, S and Thorne, PR and Caspi, A and Moffitt, TE and Hariri, AR},
Title = {Functional topography of the neocortex predicts covariation
in complex cognitive and basic motor abilities.},
Journal = {Cerebral cortex (New York, N.Y. : 1991)},
Volume = {33},
Number = {13},
Pages = {8218-8231},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1093/cercor/bhad109},
Abstract = {Although higher-order cognitive and lower-order sensorimotor
abilities are generally regarded as distinct and studied
separately, there is evidence that they not only covary but
also that this covariation increases across the lifespan.
This pattern has been leveraged in clinical settings where a
simple assessment of sensory or motor ability (e.g. hearing,
gait speed) can forecast age-related cognitive decline and
risk for dementia. However, the brain mechanisms underlying
cognitive, sensory, and motor covariation are largely
unknown. Here, we examined whether such covariation in
midlife reflects variability in common versus distinct
neocortical networks using individualized maps of functional
topography derived from BOLD fMRI data collected in 769
45-year-old members of a population-representative cohort.
Analyses revealed that variability in basic motor but not
hearing ability reflected individual differences in the
functional topography of neocortical networks typically
supporting cognitive ability. These patterns suggest that
covariation in motor and cognitive abilities in midlife
reflects convergence of function in higher-order neocortical
networks and that gait speed may not be simply a measure of
physical function but rather an integrative index of nervous
system health.},
Doi = {10.1093/cercor/bhad109},
Key = {fds371653}
}
@article{fds362162,
Author = {Matthews, T and Qualter, P and Bryan, BT and Caspi, A and Danese, A and Moffitt, TE and Odgers, CL and Strange, L and Arseneault,
L},
Title = {The developmental course of loneliness in adolescence:
Implications for mental health, educational attainment, and
psychosocial functioning.},
Journal = {Development and psychopathology},
Volume = {35},
Number = {2},
Pages = {537-546},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1017/s0954579421001632},
Abstract = {The present study examined patterns of stability and change
in loneliness across adolescence. Data were drawn from the
Environmental Risk (E-Risk) Longitudinal Twin Study, a UK
population-representative cohort of 2,232 individuals born
in 1994 and 1995. Loneliness was assessed when participants
were aged 12 and 18. Loneliness showed modest stability
across these ages (<i>r</i> = .25). Behavioral genetic
modeling indicated that stability in loneliness was
explained largely by genetic influences (66%), while change
was explained by nonshared environmental effects (58%).
Individuals who reported loneliness at both ages were
broadly similar to individuals who only reported it at age
18, with both groups at elevated risk of mental health
problems, physical health risk behaviors, and education and
employment difficulties. Individuals who were lonely only at
age 12 generally fared better; however, they were still more
likely to finish school with lower qualifications. Positive
family influences in childhood predicted reduced risk of
loneliness at age 12, while negative peer experiences
increased the risk. Together, the findings show that while
early adolescent loneliness does not appear to exert a
cumulative burden when it persists, it is nonetheless a risk
for a range of concomitant impairments, some of which can
endure.},
Doi = {10.1017/s0954579421001632},
Key = {fds362162}
}
@article{fds370048,
Author = {Poulton, R and Caspi, A and Moffitt, TE},
Title = {Fear and anxiety: Lessons learned from the Dunedin
longitudinal study.},
Journal = {Neuroscience and biobehavioral reviews},
Volume = {148},
Pages = {105118},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1016/j.neubiorev.2023.105118},
Abstract = {Four related lines of research on anxiety were reviewed from
the 'Dunedin Study', an investigation of a representative
longitudinal birth cohort of 50-years duration, with 94%
retention at the last follow-up. Findings include: (i)
Childhood fears deemed evolutionarily-relevant may have
different pathways and/or mechanisms underlying their
emergence when compared to evolutionarilyneutral fears. (ii)
Sequential comorbidity both inside and external to the
family of disorders is the rule not the exception,
highlighting the importance of developmental history. (iii)
The developmental relationship between GAD and MDE is more
symmetric that previously assumed, with equal numbers of
persons having GAD preceding MDE and MDE preceding GAD. (iv)
PTSD in adulthood is influenced by a broad range of
childhood risk factors, sequential comorbidity is near
universal, and both high-stress life events and
mental-disorder history influence the development of PTSD.
The implications for epidemiology, nosology, the importance
of developmental history, and prevention/treatment options
are considered.},
Doi = {10.1016/j.neubiorev.2023.105118},
Key = {fds370048}
}
@article{fds370884,
Author = {Doherty, T and Dempster, E and Hannon, E and Mill, J and Poulton, R and Corcoran, D and Sugden, K and Williams, B and Caspi, A and Moffitt, TE and Delany, SJ and Murphy, TM},
Title = {A comparison of feature selection methodologies and learning
algorithms in the development of a DNA methylation-based
telomere length estimator.},
Journal = {BMC bioinformatics},
Volume = {24},
Number = {1},
Pages = {178},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1186/s12859-023-05282-4},
Abstract = {<h4>Background</h4>The field of epigenomics holds great
promise in understanding and treating disease with advances
in machine learning (ML) and artificial intelligence being
vitally important in this pursuit. Increasingly, research
now utilises DNA methylation measures at cytosine-guanine
dinucleotides (CpG) to detect disease and estimate
biological traits such as aging. Given the challenge of high
dimensionality of DNA methylation data, feature-selection
techniques are commonly employed to reduce dimensionality
and identify the most important subset of features. In this
study, our aim was to test and compare a range of
feature-selection methods and ML algorithms in the
development of a novel DNA methylation-based telomere length
(TL) estimator. We utilised both nested cross-validation and
two independent test sets for the comparisons.<h4>Results</h4>We
found that principal component analysis in advance of
elastic net regression led to the overall best performing
estimator when evaluated using a nested cross-validation
analysis and two independent test cohorts. This approach
achieved a correlation between estimated and actual TL of
0.295 (83.4% CI [0.201, 0.384]) on the EXTEND test data set.
Contrastingly, the baseline model of elastic net regression
with no prior feature reduction stage performed less well in
general-suggesting a prior feature-selection stage may have
important utility. A previously developed TL estimator,
DNAmTL, achieved a correlation of 0.216 (83.4% CI [0.118,
0.310]) on the EXTEND data. Additionally, we observed that
different DNA methylation-based TL estimators, which have
few common CpGs, are associated with many of the same
biological entities.<h4>Conclusions</h4>The variance in
performance across tested approaches shows that estimators
are sensitive to data set heterogeneity and the development
of an optimal DNA methylation-based estimator should benefit
from the robust methodological approach used in this study.
Moreover, our methodology which utilises a range of
feature-selection approaches and ML algorithms could be
applied to other biological markers and disease phenotypes,
to examine their relationship with DNA methylation and
predictive value.},
Doi = {10.1186/s12859-023-05282-4},
Key = {fds370884}
}
@article{fds368071,
Author = {Lay-Yee, R and Matthews, T and Moffitt, T and Poulton, R and Caspi, A and Milne, B},
Title = {Are trajectories of social isolation from childhood to
mid-adulthood associated with adult depression or suicide
outcomes.},
Journal = {Social psychiatry and psychiatric epidemiology},
Volume = {58},
Number = {3},
Pages = {373-382},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1007/s00127-022-02389-6},
Abstract = {<h4>Purpose</h4>Social isolation has been shown to have
negative effects on mental health outcomes though little is
known about trajectories across the life course. We examined
the relationship between trajectory groups and selected
mental health outcomes in mid-adulthood.<h4>Methods</h4>We
previously created a typology of social isolation based on
onset during the life course and persistence into adulthood,
using group-based trajectory analysis of longitudinal data
from a New Zealand birth cohort. The typology comprises four
groups: 'never-isolated', 'adult-only', 'child-only', and
'persistent (child-adult) isolation'. We undertook logistic
regression analyses of three mental health outcomes with
trajectory group as the predictor, adjusting for sex and a
range of familial and child-behavioural factors.<h4>Results</h4>Lifetime
suicide attempt, and depression and suicide ideation in
mid-adulthood were each associated with adult-only but not
child-only social isolation. Depression in mid-adulthood was
also associated with persistent child-adult social
isolation.<h4>Conclusion</h4>Although our findings are
associational and not causal, they indicate that
interrupting persistent social isolation may help to prevent
adult depression whereas halting adult social isolation may
ameliorate both depression and suicide outcomes.},
Doi = {10.1007/s00127-022-02389-6},
Key = {fds368071}
}
@article{fds361195,
Author = {Wilson, GA and Cheyne, K and Ramrakha, S and Ambler, A and Tan, GS and Caspi, A and Williams, B and Sugden, K and Houts, R and Niederer, RL and Wong, TY and Moffitt, TE and Poulton, R},
Title = {Are macular drusen in midlife a marker of accelerated
biological ageing?},
Journal = {Clinical & experimental optometry},
Volume = {106},
Number = {1},
Pages = {41-46},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/08164622.2021.2012428},
Abstract = {<h4>Clinical relevance</h4>Macular drusen are associated
with age-related maculopathy but are not an ocular
manifestation or biomarker of systemic ageing.<h4>Background</h4>Macular
drusen are the first sign of age-related maculopathy, an eye
disease for which age is the strongest risk factor. The aim
of this cohort study was to investigate whether macular
drusen in midlife - a sign of the earliest stages of
age-related macular degeneration (AMD) - are associated with
accelerated biological ageing more generally.<h4>Methods</h4>Members
of the long-running Dunedin Multidisciplinary Health and
Development Study (hereafter the Dunedin Study, n = 1037)
underwent retinal photography at their most recent
assessment at the age of 45 years. Images were graded for
the presence of AMD using a simplified scale from the
Age-Related Eye Disease Study (AREDS). Accelerated ageing
was assessed by (i) a measure of Pace of Ageing defined from
a combination of clinical and serum biomarkers obtained at
ages 26, 32, 38, and 45 years and (ii) Facial Ageing,
defined from photographs obtained at age 38 and
45 years.<h4>Results</h4>Of the 938 participants who
participated at the age 45 assessments, 834 had gradable
retinal photographs, and of these 165 (19.8%) had macular
drusen. There was no significant difference in Pace of
Ageing (<i>p</i> = .743) or Facial Ageing (<i>p</i>
= .945) among participants with and without macular
drusen.<h4>Conclusions</h4>In this representative general
population sample, macular drusen in midlife were not
associated with accelerated ageing. Future studies tracking
longitudinal changes in drusen number and severity at older
ages may reveal whether drusen are a biomarker of
accelerated ageing.},
Doi = {10.1080/08164622.2021.2012428},
Key = {fds361195}
}
@article{fds368323,
Author = {Guiney, H and Walker, R and Broadbent, J and Caspi, A and Goodin, E and Kokaua, J and Moffitt, TE and Robertson, S and Theodore, R and Poulton,
R and Endre, Z},
Title = {Kidney-Function Trajectories From Young Adulthood to
Midlife: Identifying Risk Strata and Opportunities for
Intervention.},
Journal = {Kidney international reports},
Volume = {8},
Number = {1},
Pages = {51-63},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1016/j.ekir.2022.10.005},
Abstract = {<h4>Introduction</h4>Understanding normative patterns of
change in kidney function over the life course may allow
targeting of early interventions to slow or prevent the
onset of kidney disease, but knowledge about kidney
functional change before middle age is limited. This study
used prospective longitudinal data from a representative
birth cohort to examine common patterns of change from young
to midadulthood and to identify risk factors and outcomes
associated with poorer trajectories.<h4>Methods</h4>We used
group-based trajectory modeling in the Dunedin study birth
cohort (<i>n</i> = 857) to identify the following: (i)
common kidney function trajectories between the ages 32 and
45 years, (ii) early-life factors associated with those
trajectories, (iii) modifiable physical and psychosocial
factors across adulthood associated with differences in
trajectory slope, and (iv) links between trajectories and
kidney-related outcomes at age 45 years.<h4>Results</h4>Three
trajectory groups were identified and could be
differentiated by age 32 years as follows: normal (58% of
participants), low-normal (36%), and high-risk (6%) groups.
Those from low socioeconomic backgrounds had higher odds of
following a high-risk (vs. normal) trajectory. Modifiable
factors (blood pressure, body mass index, inflammation,
glycated hemoglobin, smoking, and socioeconomic status)
across adulthood were associated with steeper age-related
declines in kidney function, particularly among those in the
low-normal and high-risk groups. Those in the low-normal and
high-risk groups also had more adverse kidney-related
outcomes at age 45 years.<h4>Conclusion</h4>The current
findings could be used to inform the development of early
interventions and point to socioeconomic conditions across
the life course and health-related risk factors and
behaviors in adulthood as kidney health promotion
targets.},
Doi = {10.1016/j.ekir.2022.10.005},
Key = {fds368323}
}
%% Chardulo Dias De Andrade, Fernanda
@article{fds375860,
Author = {Andrade, FC and Burnell, K and Godwin, J and Hoyle,
RH},
Title = {Alcohol Use and Abstinence throughout Adolescence: The
Changing Contributions of Perceived Risk of Drinking,
Opportunities to Drink, and Self-Control.},
Journal = {Substance use & misuse},
Volume = {59},
Number = {6},
Pages = {910-919},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1080/10826084.2024.2310489},
Abstract = {<i>Objective</i>: Adolescence is characterized by
psychosocial and cognitive changes that can alter the
perceived risk of negative effects of alcohol, opportunities
to drink, and self-control. Few studies have investigated
whether these factors change in their contribution to
adolescent drinking over time. This study examined
associations between perceived risk, opportunities to drink,
self-control, and past-year drinking and investigated
whether self-control buffers the effect of lower perceived
risk and frequent drinking opportunities on the probability
of past-year drinking. <i>Method</i>: Data from a four-wave
longitudinal study (2015-2020) of 2,104 North Carolina
adolescents (<i>M<sub>age</sub></i> = 12.36,
<i>SD<sub>age</sub></i> = 1.12, at Time 1) were used to
assess changes in associations between self-control,
perceived risk of drinking, and drinking opportunities on
the frequency of past-year drinking. Hypotheses were tested
using latent trajectory models. <i>Results</i>: At all
timepoints, greater perceived risk, fewer drinking
opportunities, and higher self-control were associated with
drinking abstinence in the past year. Self-control buffered
the impact of frequent drinking opportunities and lower
perceived risk on the probability of alcohol use at Times
1-3. <i>Conclusions</i>: Despite expectations that
adolescents' ability to navigate their environments improves
as they age, associations between risk, protective factors,
and past-year drinking were relatively stable over time.
Nevertheless, self-control protected against frequent
drinking opportunities and lower perceived risk. Strategies
that support or relieve the need for self-control (e.g.,
situation modification) may protect against alcohol use
throughout adolescence.},
Doi = {10.1080/10826084.2024.2310489},
Key = {fds375860}
}
@article{fds368909,
Author = {Andrade, FC and Hoyle, RH and Burnell, K},
Title = {Adjusting to the COVID-19 outbreak in the United States: The
impact of disruptions on habits and changes in health
behaviors.},
Journal = {Journal of health psychology},
Volume = {28},
Number = {14},
Pages = {1307-1319},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1177/13591053221144440},
Abstract = {The COVID-19 pandemic provides a naturalistic test of
whether pandemic-related disruptions weaken habits and
undermine behavior stability. We hypothesized that better
capacity to effortfully guide behavior (self-regulation)
would buffer this effect and be associated with behavior
stability and development of new habits to accomplish daily
behaviors. A cross-sectional study of 416 MTurk workers
recruited in April 2020 (<i>M</i><sub>age</sub> = 34.60,
<i>SD</i> = 11.51) indicated that pandemic-related
disruptions generally exceeded people's capacity to
effortfully modify their behavior. Self-regulation related
to the development of new habits and to lower likelihood
that work productivity decreased. Self-regulation also
protected against the effect of disruption on the likelihood
that substance use increased. Besides these associations,
self-regulation was largely unrelated to health-related
behaviors and, in some instances, associated with poorer
outcomes. These findings underscore the need to appreciate
the impact of contextual disruptions in interpreting and
promoting change in health-related behaviors.},
Doi = {10.1177/13591053221144440},
Key = {fds368909}
}
@article{fds370374,
Author = {Andrade, FC and Erwin, S and Burnell, K and Jackson, J and Storch, M and Nicholas, J and Zucker, N},
Title = {Intervening on Social Comparisons on Social Media:
Electronic Daily Diary Pilot Study.},
Journal = {JMIR Ment Health},
Volume = {10},
Pages = {e42024},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.2196/42024},
Abstract = {BACKGROUND: Literature has underscored the dark aspects of
social media use, including associations with depressive
symptoms, feelings of social isolation, and diminished
self-esteem. Social comparison, the process of evaluating
oneself relative to another person, is thought to contribute
to these negative experiences such that people with a
stronger tendency to compare themselves with others are
particularly susceptible to the detrimental effects of
social media. Social media as a form of social connection
and communication is nevertheless an inevitable-and arguably
integral-part of life, particularly for young adults.
Therefore, there is a need to investigate strategies that
could alter the manner in which people interact with social
media to minimize its detrimental effects and maximize the
feelings of affiliation and connection. OBJECTIVE: This
pilot study examined the feasibility, acceptability, and
effectiveness of a brief web-based intervention designed to
alter engagement with social media and promote psychological
well-being by encouraging social savoring as an alternative
to social comparison. Social savoring was operationalized as
experiencing joyful emotions related to the happiness of
someone else's experiences (ie, feeling happy for someone
else). METHODS: Following an intensive longitudinal design,
55 college students (mean age 19.29, SD 0.93 years; n=43,
78% women and n=23, 42% White) completed baseline measures
(individual differences, psychological well-being,
connectedness, and social media use) and then 14 days of
daily surveys on their social media activity and well-being.
On day 8, the group that was randomized to receive the
intervention watched a video instructing them on the skill
of social savoring and was asked to practice this skill
during days 8 to 14. RESULTS: Overall, participants reported
positive perceptions of the intervention. Participants who
watched the intervention video reported significantly higher
performance self-esteem (P=.02) at posttest than those in
the control condition, after controlling for baseline
levels. Participants also reported significantly higher
state self-esteem (P=.01) on days in which they engaged in
more social savoring while using social media, and the use
of social savoring increased significantly (P=.01) over
time, suggesting that participants found it helpful.
Participants in both conditions reported significantly lower
levels of social comparison (control: P=.01; intervention:
P=.002) and higher levels of connectedness (control: P<.001;
intervention: P=.001) at posttest than at baseline.
CONCLUSIONS: Initial evidence from this pilot study suggests
that a web-based social savoring intervention may help
minimize the potentially harmful consequences of social
media use, at least in some domains. Future work is needed
to examine the effectiveness and acceptance of this
intervention in different age groups and in clinical samples
that are in part characterized by higher levels of
comparison with others (eg, people with eating
disorders).},
Doi = {10.2196/42024},
Key = {fds370374}
}
@article{fds369357,
Author = {Andrade, FC and Hoyle, RH},
Title = {A synthesis and meta-analysis of the relationship between
trait self-control and healthier practices in physical
activity, eating, and sleep domains},
Journal = {Personality and Individual Differences},
Volume = {205},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1016/j.paid.2023.112095},
Abstract = {This paper updates and extends prior work by meta-analyzing
the fast-growing literature on the association between
individual differences in trait self-control and multiple
outcomes within the domains of physical activity, eating,
and sleep. Random-effects models with nesting by study and
sample were estimated for the aggregate association between
self-control and all health-related domains, for each domain
independently, and for moderated meta-regressions testing
whether effect sizes varied by method, measurement, and
sampling within each domain. Self-control was modestly
associated with engagement in health-related activities,
with significantly stronger associations for sleep relative
to eating and physical activity-related outcomes. Within
eating and sleep domains, associations significantly varied
as a function of outcome type and whether they were assessed
in terms of health-promotion or health-risk practices.
Findings suggest that the upper bound of what can be
predicted by individual differences in self-control varies
by health-related outcome. Importantly, smaller associations
point to the potential role of other individual differences,
contextual affordances, and biological factors in explaining
healthier physical activity, eating, and sleep-related
practices. The granular approach taken in this investigation
may ultimately aid the translation of a growing literature
on the role of individual differences in self-control into
effective health behavior maintenance and change
interventions.},
Doi = {10.1016/j.paid.2023.112095},
Key = {fds369357}
}
@article{fds369074,
Author = {Meyerson, WU and Fineberg, SK and Song, YK and Faber, A and Ash, G and Andrade, FC and Corlett, P and Gerstein, MB and Hoyle,
RH},
Title = {Estimation of Bedtimes of Reddit Users: Integrated Analysis
of Time Stamps and Surveys.},
Journal = {JMIR formative research},
Volume = {7},
Pages = {e38112},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.2196/38112},
Abstract = {<h4>Background</h4>Individuals with later bedtimes have an
increased risk of difficulties with mood and substances. To
investigate the causes and consequences of late bedtimes and
other sleep patterns, researchers are exploring social media
as a data source. Pioneering studies inferred sleep patterns
directly from social media data. While innovative, these
efforts are variously unscalable, context dependent,
confined to specific sleep parameters, or rest on untested
assumptions, and none of the reviewed studies apply to the
popular Reddit platform or release software to the research
community.<h4>Objective</h4>This study builds on this prior
work. We estimate the bedtimes of Reddit users from the
times tamps of their posts, test inference validity against
survey data, and release our model as an R package (The R
Foundation).<h4>Methods</h4>We included 159 sufficiently
active Reddit users with known time zones and known,
nonanomalous bedtimes, together with the time stamps of
their 2.1 million posts. The model's form was chosen by
visualizing the aggregate distribution of the timing of
users' posts relative to their reported bedtimes. The chosen
model represents a user's frequency of Reddit posting by
time of day, with a flat portion before bedtime and a
quadratic depletion that begins near the user's bedtime,
with parameters fitted to the data. This model estimates the
bedtimes of individual Reddit users from the time stamps of
their posts. Model performance is assessed through k-fold
cross-validation. We then apply the model to estimate the
bedtimes of 51,372 sufficiently active, nonbot Reddit users
with known time zones from the time stamps of their 140
million posts.<h4>Results</h4>The Pearson correlation
between expected and observed Reddit posting frequencies in
our model was 0.997 on aggregate data. On average, posting
starts declining 45 minutes before bedtime, reaches a nadir
4.75 hours after bedtime that is 87% lower than the daytime
rate, and returns to baseline 10.25 hours after bedtime. The
Pearson correlation between inferred and reported bedtimes
for individual users was 0.61 (P<.001). In 90 of 159 cases
(56.6%), our estimate was within 1 hour of the reported
bedtime; 128 cases (80.5%) were within 2 hours. There was
equivalent accuracy in hold-out sets versus training sets of
k-fold cross-validation, arguing against overfitting. The
model was more accurate than a random forest
approach.<h4>Conclusions</h4>We uncovered a simple,
reproducible relationship between Reddit users' reported
bedtimes and the time of day when high daytime posting rates
transition to low nighttime posting rates. We captured this
relationship in a model that estimates users' bedtimes from
the time stamps of their posts. Limitations include
applicability only to users who post frequently, the
requirement for time zone data, and limits on
generalizability. Nonetheless, it is a step forward for
inferring the sleep parameters of social media users
passively at scale. Our model and precomputed estimated
bedtimes of 50,000 Reddit users are freely
available.},
Doi = {10.2196/38112},
Key = {fds369074}
}
%% Chartrand, Tanya L.
@article{fds369097,
Author = {Brick, DJ and Wight, KG and Bettman, JR and Chartrand, TL and Fitzsimons, GJ},
Title = {Celebrate Good Times: How Celebrations Increase Perceived
Social Support},
Journal = {Journal of Public Policy and Marketing},
Volume = {42},
Number = {2},
Pages = {115-132},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1177/07439156221145696},
Abstract = {Despite the ubiquity of celebrations in everyday life,
little is known about how celebrations may contribute to
consumer well-being. In the current work, the authors
propose that celebrations promote perceived social support,
which prior work has conceptualized as the belief that
others will be there for you for future negative life
events. The authors further theorize that celebrations
require three key characteristics that, in combination, are
necessary for increasing perceived social support.
Specifically, celebrations must (1) mark an individual's
separate positive event and (2) involve consumption (3) with
others (i.e., social). They test this theory across eight
studies and demonstrate a process mechanism for this effect:
these characteristics lead to increases in enacted support
and perceived responsiveness, which in turn lead to
increases in more general perceived social support. They
then extend these findings by investigating virtually held
celebrations, the individual's role at the celebration, and
a downstream prosocial outcome. By doing so, this work
highlights the broader benefits of celebrations beyond the
focal individual and the immediate experience. Finally,
specific policy implications and suggestions for enhancing
consumer well-being are provided.},
Doi = {10.1177/07439156221145696},
Key = {fds369097}
}
%% Cogan, Gregory
@article{fds370963,
Author = {Barth, KJ and Sun, J and Chiang, C-H and Qiao, S and Wang, C and Rahimpour,
S and Trumpis, M and Duraivel, S and Dubey, A and Wingel, KE and Voinas,
AE and Ferrentino, B and Doyle, W and Southwell, DG and Haglund, MM and Vestal, M and Harward, SC and Solzbacher, F and Devore, S and Devinsky,
O and Friedman, D and Pesaran, B and Sinha, SR and Cogan, GB and Blanco, J and Viventi, J},
Title = {Flexible, high-resolution cortical arrays with large
coverage capture microscale high-frequency oscillations in
patients with epilepsy.},
Journal = {Epilepsia},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1111/epi.17642},
Abstract = {OBJECTIVE: Effective surgical treatment of drug-resistant
epilepsy depends on accurate localization of the
epileptogenic zone (EZ). High-frequency oscillations (HFOs)
are potential biomarkers of the EZ. Previous research has
shown that HFOs often occur within submillimeter areas of
brain tissue and that the coarse spatial sampling of
clinical intracranial electrode arrays may limit the
accurate capture of HFO activity. In this study, we sought
to characterize microscale HFO activity captured on thin,
flexible microelectrocorticographic (μECoG) arrays, which
provide high spatial resolution over large cortical surface
areas. METHODS: We used novel liquid crystal polymer
thin-film μECoG arrays (.76-1.72-mm intercontact spacing)
to capture HFOs in eight intraoperative recordings from
seven patients with epilepsy. We identified ripple
(80-250 Hz) and fast ripple (250-600 Hz) HFOs using a
common energy thresholding detection algorithm along with
two stages of artifact rejection. We visualized microscale
subregions of HFO activity using spatial maps of HFO rate,
signal-to-noise ratio, and mean peak frequency. We
quantified the spatial extent of HFO events by measuring
covariance between detected HFOs and surrounding activity.
We also compared HFO detection rates on microcontacts to
simulated macrocontacts by spatially averaging data.
RESULTS: We found visually delineable subregions of elevated
HFO activity within each μECoG recording. Forty-seven
percent of HFOs occurred on single 200-μm-diameter
recording contacts, with minimal high-frequency activity on
surrounding contacts. Other HFO events occurred across
multiple contacts simultaneously, with covarying activity
most often limited to a .95-mm radius. Through spatial
averaging, we estimated that macrocontacts with 2-3-mm
diameter would only capture 44% of the HFOs detected in our
μECoG recordings. SIGNIFICANCE: These results demonstrate
that thin-film microcontact surface arrays with both
highresolution and large coverage accurately capture
microscale HFO activity and may improve the utility of HFOs
to localize the EZ for treatment of drug-resistant
epilepsy.},
Doi = {10.1111/epi.17642},
Key = {fds370963}
}
%% Coie, John D.
@article{fds374396,
Author = {Musci, RJ and Kush, JM and Masyn, KE and Esmaeili, MA and Susukida, R and Goulter, N and McMahon, R and Eddy, JM and Ialongo, NS and Tolan, P and Godwin, J and Conduct Problems Prevention Research Group6, and Wilcox, HC},
Title = {Psychosis Symptom Trajectories Across Childhood and
Adolescence in Three Longitudinal Studies: An Integrative
Data Analysis with Mixture Modeling.},
Journal = {Prevention science : the official journal of the Society for
Prevention Research},
Volume = {24},
Number = {8},
Pages = {1636-1647},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1007/s11121-023-01581-7},
Abstract = {Psychotic-like experiences (PLEs) are common throughout
childhood, and the presence of these experiences is a
significant risk factor for poor mental health later in
development. Given the association of PLEs with a broad
number of mental health diagnoses, these experiences serve
as an important malleable target for early preventive
interventions. However, little is known about these
experiences across childhood. While these experiences may be
common, longitudinal measurement in non-clinical settings is
not. Therefore, in order to explore longitudinal
trajectories of PLEs in childhood, we harmonized three
school-based randomized control trials with longitudinal
follow-up to identify heterogeneity in trajectories of these
experiences. In an integrative data analysis (IDA) using
growth mixture modeling, we identified three latent
trajectory classes. One trajectory class was characterized
by persistent PLEs, one was characterized by high initial
probabilities but improving across the analytic period, and
one was characterized by no reports of PLEs. Compared to the
class without PLEs, those in the improving class were more
likely to be male and have higher levels of aggressive and
disruptive behavior at baseline. In addition to the
substantive impact this work has on PLE research, we also
discuss the methodological innovation as it relates to IDA.
This IDA demonstrates the complexity of pooling data across
multiple studies to estimate longitudinal mixture
models.},
Doi = {10.1007/s11121-023-01581-7},
Key = {fds374396}
}
%% Compton, Scott N.
@article{fds376089,
Author = {Barber, KE and Woods, DW and Ely, LJ and Saunders, SM and Compton, SN and Neal-Barnett, A and Franklin, ME and Capriotti, MR and Conelea, CA and Twohig, MP},
Title = {Long-term follow-up of acceptance-enhanced behavior therapy
for trichotillomania.},
Journal = {Psychiatry Res},
Volume = {333},
Pages = {115767},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1016/j.psychres.2024.115767},
Abstract = {Acceptance-enhanced behavior therapy for trichotillomania
(AEBT-TTM) is effective in reducing trichotillomania (TTM)
symptoms, but the durability of treatment effects remains in
question. This study analyzed 6-month follow-up data from a
large randomized clinical trial comparing AEBT-TTM to an
active psychoeducation and supportive therapy control (PST).
Adults with TTM (N=85; 92% women) received 10 sessions of
AEBT-TTM or PST across 12 weeks. Independent evaluators
assessed participants at baseline, post-treatment, and 6
months follow-up. For both AEBT-TTM and PST, self-reported
and evaluator-rated TTM symptom severity decreased from
baseline to follow-up. TTM symptoms did not worsen from
post-treatment to follow-up. At follow-up, AEBT-TTM and PST
did not differ in rates of treatment response, TTM
diagnosis, or symptom severity. High baseline TTM symptom
severity was a stronger predictor of high follow-up severity
for PST than for AEBT-TTM, suggesting AEBT-TTM may be a
better option for more severe TTM. Results support the
efficacy of AEBT-TTM and show that treatment gains were
maintained over time. Although AEBT-TTM yielded lower
symptoms at post-treatment, 6-month follow-up outcomes
suggest AEBT-TTM and PST may lead to similar symptom levels
in the longer term. Future research should examine
mechanisms that contribute to long-term gain
maintenance.},
Doi = {10.1016/j.psychres.2024.115767},
Key = {fds376089}
}
@article{fds376738,
Author = {Kolitsopoulos, F and Ramaker, S and Chappell, P and Broderick, S and Bao, W and Lokhnygina, Y and Compton, S and Orazem,
J},
Title = {Response to Chadi A. Calarge re: "Effects of Long-Term
Sertraline Use on Pediatric Growth and Development: The
Sertraline Pediatric Registry for the Evaluation of Safety
(SPRITES)".},
Journal = {J Child Adolesc Psychopharmacol},
Volume = {34},
Number = {2},
Pages = {104-105},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1089/cap.2023.0085},
Doi = {10.1089/cap.2023.0085},
Key = {fds376738}
}
@article{fds371870,
Author = {Barber, KE and Woods, DW and Bauer, CC and Twohig, MP and Saunders, SM and Compton, SN and Franklin, ME},
Title = {Psychometric Properties of Trichotillomania Severity
Measures},
Journal = {Cognitive Therapy and Research},
Volume = {48},
Number = {1},
Pages = {18-29},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1007/s10608-023-10406-4},
Abstract = {Background: Trichotillomania (TTM) is a psychiatric disorder
that leads to significant hair loss, distress, and
impairment. Few validated measures exist to assess TTM, and
psychometric research examining these tools is sparse. This
study evaluated the psychometric properties of commonly used
TTM severity measures and extended prior research by
including hair loss severity ratings in our analyses.
Methods: Participants included 91 adults (92.3% Female; M
age = 35.0) with TTM who completed baseline assessments as
part of a randomized clinical trial of psychotherapy for
TTM. TTM measures included the Massachusetts General
Hospital Hairpulling Scale (MGH-HS) and National Institute
of Mental Health Trichotillomania Severity Scale (NIMH-TSS).
Independent evaluators rated photos of participants’ most
severely affected pulling sites using a one-item hair loss
severity scale. Results: Results showed mixed psychometric
properties for TTM measures. The MGH-HS showed acceptable
internal consistency (alpha = 0.83; omega = 0.89), while the
NIMH-TSS had lower internal consistency (alpha = 0.52; omega
= 0.73). Both the MGH-HS and NIMH-TSS demonstrated low
test-retest reliability. Total scores on the MGH-HS and
NIMH-TSS were not associated with hair loss severity.
Conclusions: Given these findings, it is imperative to
develop new, psychometrically-sound TTM measures. These
results also emphasize the importance of a multi-method
approach to TTM assessment. In addition to self-report and
clinician-administered measures, hair loss severity ratings
may offer valuable information as part of a comprehensive
assessment of TTM.},
Doi = {10.1007/s10608-023-10406-4},
Key = {fds371870}
}
@article{fds372713,
Author = {Barber, KE and Capel, LK and Merl, N and Twohig, MP and Saunders, SM and Compton, SN and Franklin, ME and Woods, DW},
Title = {Pulling Sites in Trichotillomania: Exploring Differences in
Characteristics, Phenomenology, and Contextual
Variables},
Journal = {Cognitive Therapy and Research},
Volume = {48},
Number = {1},
Pages = {164-176},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1007/s10608-023-10419-z},
Abstract = {Introduction: Trichotillomania is a heterogeneous disorder
with a wide range of presentations. Past studies have
described the phenomenology of trichotillomania, but
individual differences based on the body site from which
hair is pulled have not been thoroughly explored. Contextual
variables relevant to pulling (e.g., settings, tool use) may
vary as a function of pulling site. We constructed a
detailed profile of individual and clinical characteristics
based on pulling site and describe contextual factors
associated with different pulling sites. Methods: Data were
drawn from two randomized control trials of psychotherapy
for trichotillomania. Participants included
treatment-seeking adults with trichotillomania (N = 153; 89%
women; Mage=33.41) who took part in either a face-to-face (n
= 92) or an online (n = 61) trial. Study 1 explored
differences in age, gender, trichotillomania symptom
severity, and levels of automatic and focused pulling as a
function of pulling site. Study 2 included a subset of Study
1 participants (n = 65) and examined pulling site
differences for relevant contextual variables. Results:
Study 1 revealed differences in age, gender, and level of
automatic vs. focused pulling based on pulling site. Study 2
showed that pulling from different bodily sites was more
likely to occur in specific settings and with certain tools.
Discussion: These results reflect considerable variability
in the phenomenology of trichotillomania across pulling
sites and contribute to the overall understanding of
trichotillomania. A clearer picture of contextual cues and
clinical characteristics for different hair pulling sites
has treatment implications. Clinical applications and future
research directions are discussed.},
Doi = {10.1007/s10608-023-10419-z},
Key = {fds372713}
}
@article{fds375366,
Author = {Rabner, J and Olino, TM and Albano, AM and Keeton, CP and Sakolsky, D and Birmaher, B and Piacentini, J and Peris, TS and Compton, SN and Gosch,
E and Ginsburg, GS and Pinney, EL and Kendall, PC},
Title = {Substance use outcomes from the Child/Adolescent Anxiety
Multimodal Extended Long-term Study (CAMELS).},
Journal = {J Child Psychol Psychiatry},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1111/jcpp.13926},
Abstract = {BACKGROUND: Substance use problems and anxiety disorders are
both highly prevalent and frequently cooccur in youth. The
present study examined the benefits of successful anxiety
treatment at 3-12 years after treatment completion on
substance use outcomes (i.e. diagnoses and lifetime expected
use). METHODS: The sample was from the Child/Adolescent
Anxiety Multimodal Extended Long-term Study (CAMELS), a
naturalistic follow-up study to the Child/Adolescent Anxiety
Multimodal Study (CAMS) which randomized youth to cognitive
behavioral therapy (CBT; Coping cat), medication
(sertraline), their combination, or pill placebo. The first
CAMELS visit occurred an average of 6.5 years following
CAMS randomization. Participants were 319 youth (65.4% of
the CAMS sample), aged 7-17 years at CAMS baseline
assessment with a mean age of 17.6 years (range:
11-26 years) at the time of the first CAMELS follow-up.
Substance use outcomes included diagnoses as well as
lifetime substance use (i.e. alcohol and tobacco use).
RESULTS: Eleven of 319 (3.4%) CAMELS participants were
diagnosed with a substance use disorder at the initial
follow-up visit. When compared to the population lifetime
rate of 11.4%, the rate of diagnoses in the posttreated
sample was significantly lower. Additionally, rates of
lifetime alcohol use were lower than population rates at the
initial and final follow-up visits. Rates of lifetime
tobacco use were similarly lower than lifetime population
rates at the initial visit (driven by significantly lower
rates in the CBT treatment condition), but higher by the
final visit. Furthermore, treatment remission (but not
treatment response) was associated with a lower rate of
substance use diagnoses at the initial follow-up visit,
although rates of lifetime alcohol and tobacco use did not
differ by treatment outcome. CONCLUSIONS: Anxiety treatments
confer a beneficial impact on problematic substance use
(i.e. diagnoses) as well as on expected substance use (i.e.
alcohol and tobacco use) for on average, a period of
6.5 years.},
Doi = {10.1111/jcpp.13926},
Key = {fds375366}
}
@article{fds363252,
Author = {Babiano-Espinosa, L and Skarphedinsson, G and Weidle, B and Wolters,
LH and Compton, S and Ivarsson, T and Skokauskas,
N},
Title = {eCBT Versus Standard Individual CBT for Paediatric
Obsessive-Compulsive Disorder.},
Journal = {Child Psychiatry Hum Dev},
Volume = {54},
Number = {6},
Pages = {1567-1576},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1007/s10578-022-01350-7},
Abstract = {Obsessive-compulsive disorder (OCD) is characterized by
recurring obsessions and compulsions often with severe
impairment affecting 1-3% of children and adolescents.
Cognitive behavioural therapy (CBT) is the therapeutic
golden standard for paediatric OCD. However, face-to-face
CBT is limited by accessibility, availability, and quality
of delivery. Enhanced CBT (eCBT) a combination of
face-to-face sessions at the clinic and treatment at home
via webcam and a supportive app system aims to address some
of these barriers. In this pilot study, we compared eCBT
outcomes of 25 paediatric patients with OCD benchmarked
against traditional face-to-face CBT (n = 269) from the
Nordic Long-term OCD Treatment Study, the largest paediatric
OCD CBT study to date. Pairwise comparisons showed no
difference between eCBT and NordLOTS treatment outcomes.
Mean estimate difference was 2.5 in favour of eCBT (95% CI
- 0.3 to 5.3). eCBT compared to NordLOTS showed no
significant differences between response and remission
rates, suggesting similar effectiveness.},
Doi = {10.1007/s10578-022-01350-7},
Key = {fds363252}
}
@article{fds373921,
Author = {Fleischer, NJ and Gosch, E and Roberts, MB and Albano, AM and Ginsburg,
G and Piacentini, J and Birmaher, B and Compton, SN and Walkup, J and Kendall, PC and Carper, MM},
Title = {Asthma and anxiety in children and adolescents:
characteristics and treatment outcomes.},
Journal = {J Asthma},
Pages = {1-9},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1080/02770903.2023.2280906},
Abstract = {OBJECTIVE: This study (a) examined anxious youth with and
without asthma on measures of negative self-talk, parental
psychopathology, worry content, physical symptoms, panic
symptoms, generalized symptoms, and separation anxiety
symptoms, and (b) tested if outpatient CBT or medication
were differentially effective in reducing anxiety for youth
with asthma and anxiety. METHODS: This secondary analysis
separated youth with an anxiety disorder into asthma and
non-asthma groups. Youth were also compared on response to
treatments (i.e. CBT, sertraline, combined, and placebo).
RESULTS: A total of 488 participants participated in the
original study, with an average age of 10 years (SD 2.87).
Youth with comorbid asthma and anxiety demonstrated higher
rates of negative self-talk. Youth with comorbid asthma and
anxiety did not differ from the non-asthma group on measures
of physical symptoms, anxiety disorder specific symptoms,
parental psychopathology, or worry content. Youth with
asthma and anxiety responded similarly to the non-asthma
group to treatment across treatment conditions. CONCLUSIONS:
Treatment was comparably effective for youth with comorbid
asthma and anxiety and youth with anxiety. Future research
could examine the effects of psychopharmaceuticals on asthma
and anxiety comorbidity.},
Doi = {10.1080/02770903.2023.2280906},
Key = {fds373921}
}
@article{fds373395,
Author = {Perochon, S and Di Martino and JM and Carpenter, KLH and Compton, S and Davis, N and Eichner, B and Espinosa, S and Franz, L and Krishnappa
Babu, PR and Sapiro, G and Dawson, G},
Title = {Early detection of autism using digital behavioral
phenotyping.},
Journal = {Nat Med},
Volume = {29},
Number = {10},
Pages = {2489-2497},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1038/s41591-023-02574-3},
Abstract = {Early detection of autism, a neurodevelopmental condition
associated with challenges in social communication, ensures
timely access to intervention. Autism screening
questionnaires have been shown to have lower accuracy when
used in real-world settings, such as primary care, as
compared to research studies, particularly for children of
color and girls. Here we report findings from a multiclinic,
prospective study assessing the accuracy of an autism
screening digital application (app) administered during a
pediatric well-child visit to 475 (17-36 months old)
children (269 boys and 206 girls), of which 49 were
diagnosed with autism and 98 were diagnosed with
developmental delay without autism. The app displayed
stimuli that elicited behavioral signs of autism, quantified
using computer vision and machine learning. An algorithm
combining multiple digital phenotypes showed high diagnostic
accuracy with the area under the receiver operating
characteristic curve = 0.90, sensitivity = 87.8%,
specificity = 80.8%, negative predictive
value = 97.8% and positive predictive value = 40.6%.
The algorithm had similar sensitivity performance across
subgroups as defined by sex, race and ethnicity. These
results demonstrate the potential for digital phenotyping to
provide an objective, scalable approach to autism screening
in real-world settings. Moreover, combining results from
digital phenotyping and caregiver questionnaires may
increase autism screening accuracy and help reduce
disparities in access to diagnosis and intervention.},
Doi = {10.1038/s41591-023-02574-3},
Key = {fds373395}
}
@article{fds370238,
Author = {Bai, S and Rolon-Arroyo, B and Walkup, JT and Kendall, PC and Ginsburg,
GS and Keeton, CP and Albano, AM and Compton, SN and Sakolsky, D and Piacentini, J and Peris, TS},
Title = {Anxiety symptom trajectories from treatment to 5- to 12-year
follow-up across childhood and adolescence.},
Journal = {J Child Psychol Psychiatry},
Volume = {64},
Number = {9},
Pages = {1336-1345},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1111/jcpp.13796},
Abstract = {OBJECTIVE: The current study examined trajectories of
anxiety during (a) acute treatment and (b) extended
follow-up to better characterize the long-term symptom
trajectories of youth who received evidence-based
intervention for anxiety disorders using a person-centered
approach. METHOD: Participants were 319 youth (age
7-17 years at enrollment), who participated in a
multicenter randomized controlled trial for the treatment of
pediatric anxiety disorders, Child/Adolescent Anxiety
Multimodal Study, and a 4-year naturalistic follow-up,
Child/Adolescent Anxiety Multimodal Extended Long-term
Study, an average of 6.5 years later. Using growth mixture
modeling, the study identified distinct trajectories of
anxiety across acute treatment (Weeks 0-12), posttreatment
(Weeks 12-36), and the 4-year-long follow-up, and identified
baseline predictors of these trajectories. RESULTS: Three
nonlinear anxiety trajectories emerged: "short-term
responders" who showed rapid treatment response but had
higher levels of anxiety during the extended follow-up;
"durable responders" who sustained treatment gains; and
"delayed remitters" who did not show an initial response to
treatment, but showed low levels of anxiety during the
maintenance and extended follow-up periods. Worse anxiety
severity and better family functioning at baseline predicted
membership in the delayed remitters group. Caregiver strain
differentiated short-term responders from durable
responders. CONCLUSIONS: Findings suggest that initial
response to treatment does not guarantee sustained treatment
gains over time for some youth. Future follow-up studies
that track treated youth across key developmental
transitions and in the context of changing social
environments are needed to inform best practices for the
long-term management of anxiety.},
Doi = {10.1111/jcpp.13796},
Key = {fds370238}
}
@article{fds371262,
Author = {Coffman, M and Di Martino and JM and Aiello, R and Carpenter, KLH and Chang, Z and Compton, S and Eichner, B and Espinosa, S and Flowers, J and Franz, L and Perochon, S and Krishnappa Babu and PR and Sapiro, G and Dawson, G},
Title = {Relationship between quantitative digital behavioral
features and clinical profiles in young autistic
children.},
Journal = {Autism Res},
Volume = {16},
Number = {7},
Pages = {1360-1374},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1002/aur.2955},
Abstract = {Early behavioral markers for autism include differences in
social attention and orienting in response to one's name
when called, and differences in body movements and motor
abilities. More efficient, scalable, objective, and reliable
measures of these behaviors could improve early screening
for autism. This study evaluated whether objective and
quantitative measures of autism-related behaviors elicited
from an app (SenseToKnow) administered on a smartphone or
tablet and measured via computer vision analysis (CVA) are
correlated with standardized caregiver-report and clinician
administered measures of autism-related behaviors and
cognitive, language, and motor abilities. This is an
essential step in establishing the concurrent validity of a
digital phenotyping approach. In a sample of 485 toddlers,
43 of whom were diagnosed with autism, we found that
CVA-based gaze variables related to social attention were
associated with the level of autism-related behaviors. Two
language-related behaviors measured via the app, attention
to people during a conversation and responding to one's name
being called, were associated with children's language
skills. Finally, performance during a bubble popping game
was associated with fine motor skills. These findings
provide initial support for the concurrent validity of the
SenseToKnow app and its potential utility in identifying
clinical profiles associated with autism. Future research is
needed to determine whether the app can be used as an autism
screening tool, can reliably stratify autism-related
behaviors, and measure changes in autism-related behaviors
over time.},
Doi = {10.1002/aur.2955},
Key = {fds371262}
}
@article{fds371745,
Author = {Krishnappa Babu and PR and Aikat, V and Di Martino and JM and Chang, Z and Perochon, S and Espinosa, S and Aiello, R and L H Carpenter and K and Compton, S and Davis, N and Eichner, B and Flowers, J and Franz, L and Dawson, G and Sapiro, G},
Title = {Blink rate and facial orientation reveal distinctive
patterns of attentional engagement in autistic toddlers: a
digital phenotyping approach.},
Journal = {Sci Rep},
Volume = {13},
Number = {1},
Pages = {7158},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1038/s41598-023-34293-7},
Abstract = {Differences in social attention are well-documented in
autistic individuals, representing one of the earliest signs
of autism. Spontaneous blink rate has been used to index
attentional engagement, with lower blink rates reflecting
increased engagement. We evaluated novel methods using
computer vision analysis (CVA) for automatically quantifying
patterns of attentional engagement in young autistic
children, based on facial orientation and blink rate, which
were captured via mobile devices. Participants were 474
children (17-36 months old), 43 of whom were diagnosed with
autism. Movies containing social or nonsocial content were
presented via an iPad app, and simultaneously, the device's
camera recorded the children's behavior while they watched
the movies. CVA was used to extract the duration of time the
child oriented towards the screen and their blink rate as
indices of attentional engagement. Overall, autistic
children spent less time facing the screen and had a higher
mean blink rate compared to neurotypical children.
Neurotypical children faced the screen more often and
blinked at a lower rate during the social movies compared to
the nonsocial movies. In contrast, autistic children faced
the screen less often during social movies than during
nonsocial movies and showed no differential blink rate to
social versus nonsocial movies.},
Doi = {10.1038/s41598-023-34293-7},
Key = {fds371745}
}
@article{fds370239,
Author = {Ong, CW and Woods, DW and Franklin, ME and Saunders, SM and Neal-Barnett, AM and Compton, SN and Twohig, MP},
Title = {The role of psychological flexibility in acceptance-enhanced
behavior therapy for trichotillomania: Moderation and
mediation findings.},
Journal = {Behav Res Ther},
Volume = {164},
Pages = {104302},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1016/j.brat.2023.104302},
Abstract = {Trichotillomania is characterized by recurrent pulling out
of one's hair, leading to significant hair loss and
accompanied by clinically significant distress and/or
functional impairment. The current study used data from a
randomized controlled trial comparing the effectiveness of
acceptance-enhanced behavior therapy (AEBT) to
psychoeducation plus supportive therapy (PST; active
control) for trichotillomania in an adult sample. The
objectives were to examine the moderating and mediating
influence of trichotillomania-specific psychological
flexibility in treatment for trichotillomania. Participants
with lower baseline flexibility performed better in AEBT
than PST in terms of greater symptom reduction and quality
of life. Lower baseline flexibility also predicted higher
likelihood of disorder recovery in AEBT relative to PST. In
addition, relative to PST, symptom reduction in AEBT was
mediated by psychological flexibility, controlling for
anxiety and depression. These findings suggest that
psychological flexibility is a relevant process of change in
the treatment of trichotillomania. Clinical implications and
directions for future research are discussed.},
Doi = {10.1016/j.brat.2023.104302},
Key = {fds370239}
}
@article{fds370624,
Author = {Isaev, DY and Sabatos-DeVito, M and Di Martino and JM and Carpenter, K and Aiello, R and Compton, S and Davis, N and Franz, L and Sullivan, C and Dawson, G and Sapiro, G},
Title = {Computer Vision Analysis of Caregiver-Child Interactions in
Children with Neurodevelopmental Disorders: A Preliminary
Report.},
Journal = {J Autism Dev Disord},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1007/s10803-023-05973-0},
Abstract = {We report preliminary results of computer vision analysis of
caregiver-child interactions during free play with children
diagnosed with autism (N = 29, 41-91 months),
attention-deficit/hyperactivity disorder (ADHD, N = 22,
48-100 months), or combined autism + ADHD (N = 20,
56-98 months), and neurotypical children (NT, N = 7,
55-95 months). We conducted micro-analytic analysis of
'reaching to a toy,' as a proxy for initiating or responding
to a toy play bout. Dyadic analysis revealed two clusters of
interaction patterns, which differed in frequency of
'reaching to a toy' and caregivers' contingent responding to
the child's reach for a toy by also reaching for a toy.
Children in dyads with higher caregiver responsiveness had
less developed language, communication, and socialization
skills. Clusters were not associated with diagnostic groups.
These results hold promise for automated methods of
characterizing caregiver responsiveness in dyadic
interactions for assessment and outcome monitoring in
clinical trials.},
Doi = {10.1007/s10803-023-05973-0},
Key = {fds370624}
}
@article{fds369896,
Author = {Rabner, JC and Olino, TM and Albano, AM and Ginsburg, GS and Compton,
SN and Piacentini, J and Sakolsky, D and Birmaher, B and Gosch, E and Kendall, PC},
Title = {Do youth anxiety measures assess the same construct
consistently throughout treatment? Results
are...complicated.},
Journal = {Child Psychiatry Hum Dev},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1007/s10578-023-01515-y},
Abstract = {Interventionists interpret changes in symptoms as reflecting
response to treatment. However, changes in symptom
functioning and the measurement of the underlying constructs
may be reflected in reported change. Longitudinal
measurement invariance (LMI) is a statistical approach that
assesses the degree to which measures consistently capture
the same construct over time. We examined LMI in measures of
anxiety severity/symptoms [i.e., Pediatric Anxiety Rating
Scale (PARS), Multidimensional Anxiety Scale for Children
(MASC), Screen for Child Anxiety and Related Disorders
(SCARED)] in anxious youth at baseline and posttreatment.
Initial fit was inadequate for 27 of 38 baseline and
posttreatment models, but model modifications resulted in
acceptable fit. Tests of LMI supported scalar invariance for
the PARS and many, but not all, MASC and SCARED subscales.
Findings suggest that the PARS, and many MASC and SCARED
subscales can accurately be used to measure change over
time, however, others may reflect changes in measurement
properties.},
Doi = {10.1007/s10578-023-01515-y},
Key = {fds369896}
}
@article{fds369350,
Author = {Perochon, S and Matias Di Martino and J and Carpenter, KLH and Compton,
S and Davis, N and Espinosa, S and Franz, L and Rieder, AD and Sullivan, C and Sapiro, G and Dawson, G},
Title = {A tablet-based game for the assessment of visual motor
skills in autistic children.},
Journal = {NPJ Digit Med},
Volume = {6},
Number = {1},
Pages = {17},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1038/s41746-023-00762-6},
Abstract = {Increasing evidence suggests that early motor impairments
are a common feature of autism. Thus, scalable, quantitative
methods for measuring motor behavior in young autistic
children are needed. This work presents an engaging and
scalable assessment of visual-motor abilities based on a
bubble-popping game administered on a tablet. Participants
are 233 children ranging from 1.5 to 10 years of age (147
neurotypical children and 86 children diagnosed with autism
spectrum disorder [autistic], of which 32 are also diagnosed
with co-occurring attention-deficit/hyperactivity disorder
[autistic+ADHD]). Computer vision analyses are used to
extract several game-based touch features, which are
compared across autistic, autistic+ADHD, and neurotypical
participants. Results show that younger (1.5-3 years)
autistic children pop the bubbles at a lower rate, and their
ability to touch the bubble's center is less accurate
compared to neurotypical children. When they pop a bubble,
their finger lingers for a longer period, and they show more
variability in their performance. In older children
(3-10-years), consistent with previous research, the
presence of co-occurring ADHD is associated with greater
motor impairment, reflected in lower accuracy and more
variable performance. Several motor features are correlated
with standardized assessments of fine motor and cognitive
abilities, as evaluated by an independent clinical
assessment. These results highlight the potential of
touch-based games as an efficient and scalable approach for
assessing children's visual-motor skills, which can be part
of a broader screening tool for identifying early signs
associated with autism.},
Doi = {10.1038/s41746-023-00762-6},
Key = {fds369350}
}
@article{fds369776,
Author = {Kolitsopoulos, F and Ramaker, S and Compton, SN and Broderick, S and Orazem, J and Bao, W and Lokhnygina, Y and Marschall, K and Chappell,
P},
Title = {Effects of Long-Term Sertraline Use on Pediatric Growth and
Development: The Sertraline Pediatric Registry for The
Evaluation of Safety (SPRITES).},
Journal = {J Child Adolesc Psychopharmacol},
Volume = {33},
Number = {1},
Pages = {2-13},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1089/cap.2022.0048},
Abstract = {Objective: To describe the results of the Sertraline
Pediatric Registry for The Evaluation of Safety (SPRITES)
outcome measures of cognitive, emotional, and physical
development following long-term treatment with sertraline
(for up to 3 years) in children and adolescents aged 6-16
years. Methods: SPRITES was a long-term, multicenter,
open-label, prospective observational study designed to
compare physical and psychological development in pediatric
patients exposed to sertraline (with or without
psychotherapy) or psychotherapy alone in usual care
settings. Data were summarized descriptively, and outcomes
were evaluated using a marginal structural model. Results:
Between April 2012 and September 2020, 941 patients across
44 U.S. sites participated in the study. At baseline, 695
participants were exposed to sertraline (physician
prescribed) with or without psychotherapy, and 245
participants were exposed to psychotherapy alone. Of these,
432 participants (46.0%) completed the full 3-year study
follow-up. No significant changes across time were found in
standardized height, BRIEF (Behavior Rating Inventory of
Executive Function), Trails B, and Tanner stage based on
cumulative sertraline exposure or exposure since the last
visit. Change in mean standardized weight across time was
positively associated with both cumulative sertraline
exposure (p = 0.02) and exposure since the last visit
(p = 0.029). The mean changes from baseline across time
in standardized weight were standard deviations of 0.02,
0.03, 0.16, and 0.17 at months 3, 6, 30, and 36,
respectively. However, this finding was not observed in the
mean change across time in standardized body mass index,
which was not statistically significant. Conclusions:
Results are consistent with normal development. Although a
statistically significant finding for standardized weight
was observed in comparative analyses, the magnitude of the
change is small and observed at higher doses of sertraline
only. No other significant differences were observed between
the "sertraline" group and the "no pharmacological therapy"
group on other primary outcome measures. ClinicalTrials.gov
identifier: NCT01302080.},
Doi = {10.1089/cap.2022.0048},
Key = {fds369776}
}
@article{fds365567,
Author = {Krishnappa Babu and PR and Di Martino and JM and Chang, Z and Perochon, S and Aiello, R and Carpenter, KLH and Compton, S and Davis, N and Franz, L and Espinosa, S and Flowers, J and Dawson, G and Sapiro,
G},
Title = {Complexity analysis of head movements in autistic
toddlers.},
Journal = {J Child Psychol Psychiatry},
Volume = {64},
Number = {1},
Pages = {156-166},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1111/jcpp.13681},
Abstract = {BACKGROUND: Early differences in sensorimotor functioning
have been documented in young autistic children and infants
who are later diagnosed with autism. Previous research has
demonstrated that autistic toddlers exhibit more frequent
head movement when viewing dynamic audiovisual stimuli,
compared to neurotypical toddlers. To further explore this
behavioral characteristic, in this study, computer vision
(CV) analysis was used to measure several aspects of head
movement dynamics of autistic and neurotypical toddlers
while they watched a set of brief movies with social and
nonsocial content presented on a tablet. METHODS: Data were
collected from 457 toddlers, 17-36 months old, during
their well-child visit to four pediatric primary care
clinics. Forty-one toddlers were subsequently diagnosed with
autism. An application (app) displayed several brief movies
on a tablet, and the toddlers watched these movies while
sitting on their caregiver's lap. The front-facing camera in
the tablet recorded the toddlers' behavioral responses. CV
was used to measure the participants' head movement rate,
movement acceleration, and complexity using multiscale
entropy. RESULTS: Autistic toddlers exhibited significantly
higher rate, acceleration, and complexity in their head
movements while watching the movies compared to neurotypical
toddlers, regardless of the type of movie content (social
vs. nonsocial). The combined features of head movement
acceleration and complexity reliably distinguished the
autistic and neurotypical toddlers. CONCLUSIONS: Autistic
toddlers exhibit differences in their head movement dynamics
when viewing audiovisual stimuli. Higher complexity of their
head movements suggests that their movements were less
predictable and less stable compared to neurotypical
toddlers. CV offers a scalable means of detecting subtle
differences in head movement dynamics, which may be helpful
in identifying early behaviors associated with autism and
providing insight into the nature of sensorimotor
differences associated with autism.},
Doi = {10.1111/jcpp.13681},
Key = {fds365567}
}
@article{fds359489,
Author = {Babu, PRK and Di Martino and JM and Chang, Z and Perochon, S and Carpenter,
KLH and Compton, S and Espinosa, S and Dawson, G and Sapiro,
G},
Title = {Exploring Complexity of Facial Dynamics in Autism Spectrum
Disorder.},
Journal = {IEEE Trans Affect Comput},
Volume = {14},
Number = {2},
Pages = {919-930},
Year = {2023},
url = {http://dx.doi.org/10.1109/taffc.2021.3113876},
Abstract = {Atypical facial expression is one of the early symptoms of
autism spectrum disorder (ASD) characterized by reduced
regularity and lack of coordination of facial movements.
Automatic quantification of these behaviors can offer novel
biomarkers for screening, diagnosis, and treatment
monitoring of ASD. In this work, 40 toddlers with ASD and
396 typically developing toddlers were shown
developmentally-appropriate and engaging movies presented on
a smart tablet during a well-child pediatric visit. The
movies consisted of social and non-social dynamic scenes
designed to evoke certain behavioral and affective
responses. The front-facing camera of the tablet was used to
capture the toddlers' face. Facial landmarks' dynamics were
then automatically computed using computer vision
algorithms. Subsequently, the complexity of the landmarks'
dynamics was estimated for the eyebrows and mouth regions
using multiscale entropy. Compared to typically developing
toddlers, toddlers with ASD showed higher complexity (i.e.,
less predictability) in these landmarks' dynamics. This
complexity in facial dynamics contained novel information
not captured by traditional facial affect analyses. These
results suggest that computer vision analysis of facial
landmark movements is a promising approach for detecting and
quantifying early behavioral symptoms associated with
ASD.},
Doi = {10.1109/taffc.2021.3113876},
Key = {fds359489}
}
%% Craig, Maureen A.
@article{fds372821,
Author = {Wallace, LE and Craig, MA and Wegener, DT},
Title = {Biased, but expert: Trade-offs in how stigmatized versus
non-stigmatized advocates are perceived and consequences for
persuasion},
Journal = {Journal of Experimental Social Psychology},
Volume = {110},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.jesp.2023.104519},
Abstract = {Stigmatized versus non-stigmatized people advocating on
behalf of the stigmatized group are perceived as more
biased, suggesting that they might be less effective
advocates. Yet, research testing whether stigmatized or
non-stigmatized advocates are more persuasive has yielded
mixed results. The current work builds on previous research
to clarify that this occurs because stigmatized advocates
are also perceived as more expert on social justice issues.
Six studies document these trade-offs in perceptions. Three
studies demonstrate that stigmatized and non-stigmatized
advocates seem not to differ in their effectiveness because
while perceived expertise boosts the effectiveness of
stigmatized advocates, perceived bias undermines it. This
occurs both when people confront societal inequality and
interpersonal prejudice. Despite the lack of difference in
persuasiveness, people predict that the stigmatized advocate
will be more effective, suggesting that observers may not
recognize perceived bias's role in undermining
effectiveness. The present findings differ not only from
participants' lay theories, but also from conclusions
commonly reached by reviews of the literature which suggest
that stigmatized advocates may be less effective than their
non-stigmatized counterparts. By examining a broader range
of perceptions and effects on audience members' attitudes
and intentions to behave consistently with advocacy, we
provide a more complete view of these effects.},
Doi = {10.1016/j.jesp.2023.104519},
Key = {fds372821}
}
@article{fds374969,
Author = {Brown, RM and Dietze, P and Craig, MA},
Title = {Highlighting health consequences of racial disparities
sparks support for action.},
Journal = {Science (New York, N.Y.)},
Volume = {382},
Number = {6677},
Pages = {1394-1398},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1126/science.adh4262},
Abstract = {Racial disparities arise across many vital areas of American
life, including employment, health, and interpersonal
treatment. For example, one in three Black children lives in
poverty (versus one in nine white children), and, on
average, Black Americans live four fewer years compared with
white Americans. Which disparity is more likely to spark
reduction efforts? We find that highlighting disparities in
health-related (versus economic) outcomes spurs greater
social media engagement and support for disparity-mitigating
policy. Further, reading about racial health disparities
elicits greater support for action (e.g., protesting)
compared with economic- or belonging-based disparities. This
occurs in part because people view health disparities as
violating morally sacred values, which enhances perceived
injustice. This work elucidates which manifestations of
racial inequality are most likely to prompt Americans to
action.},
Doi = {10.1126/science.adh4262},
Key = {fds374969}
}
@article{fds371153,
Author = {Brown, RM and Craig, MA},
Title = {Understanding tactical responses to social problems through
the lens of regulatory scope},
Journal = {Nature Reviews Psychology},
Volume = {2},
Number = {7},
Pages = {440-449},
Publisher = {Springer Science and Business Media LLC},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1038/s44159-023-00184-x},
Abstract = {People may address societal problems either by engaging in
collective action, aiming to change underlying structural
systems, or by engaging in prosocial behaviours, aiming to
help those affected. In this Perspective, we draw on
construal level theory and regulatory scope theory to
understand how people might choose to mitigate social
problems. Specifically, we propose that people pursue
solutions that alleviate the suffering of those affected by
the problem (consequence-focused solutions) when they focus
on lower-level or more psychologically proximal features and
that they pursue solutions that address the underlying
causes of the problem (cause-focused solutions) when they
focus on higher-level or more psychologically distant
features. Thus, people’s preferences for different
solutions might be explained by understanding how people
view the underlying problem. This framework explains the
different ways people seek to address perceived social
problems, providing insights into when and why people devote
their time and energy to pursuing different forms of social
action.},
Doi = {10.1038/s44159-023-00184-x},
Key = {fds371153}
}
%% Davis, Charles
@article{fds368530,
Author = {Langland-Hassan, P and Davis, CP},
Title = {A context-sensitive and non-linguistic approach to abstract
concepts.},
Journal = {Philosophical transactions of the Royal Society of London.
Series B, Biological sciences},
Volume = {378},
Number = {1870},
Pages = {20210355},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1098/rstb.2021.0355},
Abstract = {Despite the recent upsurge in research on abstract concepts,
there remain puzzles at the foundation of their empirical
study. These are most evident when we consider what is
required to assess a person's abstract conceptual abilities
without using language as a prompt or requiring it as a
response-as in classic non-verbal categorization tasks,
which are standardly considered tests of conceptual
understanding. After distinguishing two divergent strands in
the most common conception of what it is for a concept to be
abstract, we argue that neither reliably captures the kind
of abstraction required to successfully categorize in
non-verbal tasks. We then present a new conception of
concept abstractness-termed 'trial concreteness'-that is
keyed to individual categorization trials. It has advantages
in capturing the context-relativity of the degree of
abstraction required for the application of a concept and
fittingly correlates with participant success in recent
experiments. This article is part of the theme issue
'Concepts in interaction: social engagement and inner
experiences'.},
Doi = {10.1098/rstb.2021.0355},
Key = {fds368530}
}
@article{fds370328,
Author = {Davis, CP},
Title = {Emergence of Covid‐19 as a Novel Concept Shifts Existing
Semantic Spaces},
Journal = {Cognitive Science},
Volume = {47},
Number = {1},
Publisher = {Wiley},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1111/cogs.13237},
Abstract = {<jats:title>Abstract</jats:title><jats:p>Conceptual
knowledge is dynamic, fluid, and flexible, changing as a
function of contextual factors at multiple scales. The
Covid‐19 pandemic can be considered a large‐scale,
global context that has fundamentally altered most people's
experiences with the world. It has also introduced a new
concept, <jats:italic>COVID</jats:italic> (or
<jats:italic>COVID‐19</jats:italic>), into our collective
knowledgebase. What are the implications of this
introduction for how existing conceptual knowledge is
structured? Our collective emotional and social experiences
with the world have been profoundly impacted by the
Covid‐19 pandemic, and experience‐based perspectives on
concept representation suggest that emotional and social
experiences are critical components of conceptual knowledge.
Such changes in collective experience should, then, have
downstream consequences on knowledge of emotion‐ and
social‐related concepts. Using a naturally occurring
dataset derived from the social media platform Twitter, we
show that semantic spaces for concepts related to our
emotional experiences with Covid‐19 (i.e., emotional
concepts like <jats:italic>FEAR</jats:italic>)—but not for
unrelated concepts (i.e., animals like <jats:italic>CAT</jats:italic>)—show
quantifiable shifts as a function of the emergence of
<jats:italic>COVID‐19</jats:italic> as a concept and its
associated emotional and social experiences, shifts which
persist 6 months after the onset of the pandemic. The
findings support a dynamic view of conceptual knowledge
wherein shared experiences affect conceptual
structure.</jats:p>},
Doi = {10.1111/cogs.13237},
Key = {fds370328}
}
@article{fds372715,
Author = {Davis, CP and Yee, E},
Title = {Is time an embodied property of concepts?},
Journal = {PloS one},
Volume = {18},
Number = {9},
Pages = {e0290997},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1371/journal.pone.0290997},
Abstract = {A haircut usually lasts under an hour. But how long does it
take to recognize that something is an instance of a
haircut? And is this "time-to-perceive" a part of the
representation of concepts like haircut? Across three
experiments testing lexical decision, word recognition, and
semantic decision, we show that the amount of time people
say it takes to perceive a concept in the world (e.g.,
haircut, dandelion, or merit) predicts how long it takes for
them to respond to a word referring to that thing, over and
above the effects of other lexical-semantic variables (e.g.,
word frequency, concreteness) and other variables related to
conceptual complexity (e.g., how confusable a concept is
with other, similar concepts, or the diversity of the
contexts in which a concept appears). These results suggest
that our experience of how long it takes to recognize an
instance of a concept can become a part of its
representation, and that we simulate this information when
reading words. Consequently, we suggest that time may be an
embodied property of concepts.},
Doi = {10.1371/journal.pone.0290997},
Key = {fds372715}
}
%% Dawson, Geraldine
@article{fds376260,
Author = {Griffin, JW and Webb, SJ and Keehn, B and Dawson, G and McPartland,
JC},
Title = {Autistic Individuals Do Not Alter Visual Processing Strategy
During Encoding Versus Recognition of Faces: A Hidden Markov
Modeling Approach.},
Journal = {J Autism Dev Disord},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1007/s10803-024-06259-9},
Abstract = {PURPOSE: Visual face recognition-the ability to encode,
discriminate, and recognize the faces of others-is
fundamentally supported by eye movements and is a common
source of difficulty for autistic individuals. We aimed to
evaluate how visual processing strategies (i.e., eye
movement patterns) directly support encoding and recognition
of faces in autistic and neurotypical (NT) individuals.
METHODS: We used a hidden Markov modeling approach to
evaluate the spatiotemporal dynamics of eye movements in
autistic (n = 15) and neurotypical (NT) adolescents
(n = 17) during a face identity recognition task.
RESULTS: We discovered distinct eye movement patterns among
all participants, which included a focused and exploratory
strategy. When evaluating change in visual processing
strategy across encoding and recognition phases, autistic
individuals did not shift their eye movement patterns like
their NT peers, who shifted to a more exploratory visual
processing strategy during recognition. CONCLUSION: These
findings suggest that autistic individuals do not modulate
their visual processing strategy across encoding and
recognition of faces, which may be an indicator of less
efficient face processing.},
Doi = {10.1007/s10803-024-06259-9},
Key = {fds376260}
}
@article{fds371480,
Author = {Posner, J and Dawson, G},
Title = {Addressing the Gap in Research Training in Child Psychiatry
and Neurodevelopment.},
Journal = {J Am Acad Child Adolesc Psychiatry},
Volume = {63},
Number = {2},
Pages = {105-108},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1016/j.jaac.2023.05.026},
Abstract = {Psychiatric and neurodevelopmental conditions in children
are common, often co-occur, and can be highly impairing.
Moreover, psychiatric disorders that typically do not fully
manifest until adulthood, such as schizophrenia, have their
roots in early development, with atypical brain and
behavioral patterns arising well before a clinical diagnosis
is made. The relevance of brain development to improving
outcomes of psychiatric and neurodevelopmental conditions
underscores the need to cultivate a pipeline of
investigators with the necessary training to conduct
rigorous, developmentally focused research.},
Doi = {10.1016/j.jaac.2023.05.026},
Key = {fds371480}
}
@article{fds376099,
Author = {Brandsen, S and Chandrasekhar, T and Franz, L and Grapel, J and Dawson,
G and Carlson, D},
Title = {Prevalence of bias against neurodivergence-related terms in
artificial intelligence language models.},
Journal = {Autism Res},
Volume = {17},
Number = {2},
Pages = {234-248},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1002/aur.3094},
Abstract = {Given the increasing role of artificial intelligence (AI) in
many decision-making processes, we investigate the presence
of AI bias towards terms related to a range of
neurodivergent conditions, including autism, ADHD,
schizophrenia, and obsessive-compulsive disorder (OCD). We
use 11 different language model encoders to test the degree
to which words related to neurodiversity are associated with
groups of words related to danger, disease, badness, and
other negative concepts. For each group of words tested, we
report the mean strength of association (Word Embedding
Association Test [WEAT] score) averaged over all encoders
and find generally high levels of bias. Additionally, we
show that bias occurs even when testing words associated
with autistic or neurodivergent strengths. For example,
embedders had a negative average association between words
related to autism and words related to honesty, despite
honesty being considered a common strength of autistic
individuals. Finally, we introduce a sentence similarity
ratio test and demonstrate that many sentences describing
types of disabilities, for example, "I have autism" or "I
have epilepsy," have even stronger negative associations
than control sentences such as "I am a bank
robber."},
Doi = {10.1002/aur.3094},
Key = {fds376099}
}
@article{fds373964,
Author = {Gu, Z and Dawson, G and Engelhard, M},
Title = {Sex differences in the age of childhood autism diagnosis and
the impact of co-occurring conditions.},
Journal = {Autism Res},
Volume = {16},
Number = {12},
Pages = {2391-2402},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1002/aur.3043},
Abstract = {Sex differences in the age of autism diagnosis during
childhood have been documented consistently but remain
poorly understood. In this study, we used electronic health
records data from a diverse, academic medical center to
quantify differences in the age of autism diagnosis between
boys and girls and identify associations between the age of
diagnosis and co-occurring neurodevelopmental, psychiatric,
and medical conditions. An established computable phenotype
was used to identify all autism diagnoses within the Duke
University Health System between 2014 and 2021. Co-occurring
neurodevelopmental and psychiatric diagnoses as well as
visits to specific medical and supportive services were
identified in the 2 years prior to the autism diagnosis.
Cox proportional hazards models were fitted to quantify
associations between diagnosis age and sex with and without
controlling for the presence of each co-occurring diagnosis
and visit type. Records from 1438 individuals (1142 boys and
296 girls) were included. Girls were more likely to be
diagnosed either before age 3 ( χ 2 = 497.720,
p < 0.001) or after age 11 ( χ 2 = 4.014,
p = 0.047), whereas boys were more likely to be
diagnosed between ages 3 and 11 ( χ 2 = 5.532,
p = 0.019). Visits for anxiety ( χ 2 = 4.200,
p = 0.040) and mood disorders ( χ 2 = 7.033,
p = 0.008) were more common in girls and associated with
later autism diagnosis (HR = 0.615, p < 0.001; and
HR = 0.493, p < 0.001). Visits for otolaryngology
were more common in boys and associated with an earlier
autism diagnosis (HR = 1.691, p < 0.001). After
controlling for these conditions, associations between sex
and diagnosis age were reduced and not statistically
significant. These results show that the age of autism
diagnosis differs in girls compared to boys, but these
differences were neutralized when controlling for
co-occurring neurodevelopmental and psychiatric conditions
prior to autism diagnosis. Understanding sex differences and
the possible mediating role of other diagnoses may suggest
targets for intervention to promote earlier and more
equitable diagnosis.},
Doi = {10.1002/aur.3043},
Key = {fds373964}
}
@article{fds370379,
Author = {Herkert, D and Sullivan, C and Zhu, Y and Dawson,
G},
Title = {Prevalence and nature of prior developmental and medical
concerns in toddlers who screen positive for autism in
primary care.},
Journal = {Autism},
Volume = {27},
Number = {8},
Pages = {2361-2371},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1177/13623613231162146},
Abstract = {The American Academy of Pediatrics recommends that all
children be screened for autism at their 18- and 24-month
well-child visit. For children who screen positive for
autism, it is unknown whether this usually represents the
first time a developmental concern has been raised or if
other developmental concerns typically precede a positive
autism screen. Such knowledge could help guide providers in
how to appropriately convey feedback regarding autism
screening. This study found that, for close to 80% of
children with a positive autism screen, caregivers or
providers had a prior autism, language, motor, or other
developmental concern documented in the electronic health
record. Many also had other prior concerns frequently linked
to autism, such as sleep and gastrointestinal problems, and
received physical or speech therapy. On average, prior to
screening children who received a positive
Modified-Checklist for Autism in Toddlers had two documented
concerns by at 1 year of age and three concerns by
2 years of age. These findings imply that screening for
autism as a part of routine pediatric care likely takes
place in the context of larger conversations regarding
existing developmental concerns, allowing for a less
stigmatizing discussion of autism. Framing the presence of
prior concerns in the setting of a positive screen in this
context may create a reaffirming space for existing
caregiver concerns and a lessened emotional burden on
caregivers.},
Doi = {10.1177/13623613231162146},
Key = {fds370379}
}
@article{fds370900,
Author = {Yuan, A and Sabatos-DeVito, M and Bey, AL and Major, S and Carpenter,
KL and Franz, L and Howard, J and Vermeer, S and Simmons, R and Troy, J and Dawson, G},
Title = {Automated movement tracking of young autistic children
during free play is correlated with clinical features
associated with autism.},
Journal = {Autism},
Volume = {27},
Number = {8},
Pages = {2530-2541},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1177/13623613231169546},
Abstract = {Play-based observations allow researchers to observe
autistic children across a wide range of ages and skills. We
recorded autistic children playing with toys in the center
of a room and at a corner table while a caregiver remained
seated off to the side and used video tracking technology to
track children's movement and location. We examined how time
children spent in room regions and whether or not they
approached each region during play related to their
cognitive, social, communication, and adaptive skills to
determine if tracking child movement and location can
meaningfully demonstrate clinical variation among autistic
children representing a range of ages and skills. One
significant finding was that autistic children who spent
more time in the toy-containing center of the room had
higher cognitive and language abilities, whereas those who
spent less time in the center had higher levels of
autism-related behaviors. In contrast, children who spent
more time in the caregiver region had lower daily living
skills and those who were quicker to approach the caregiver
had lower adaptive behavior and language skills. These
findings support the use of movement tracking as a
complementary method of measuring clinical differences among
autistic children. Furthermore, over 90% of autistic
children representing a range of ages and skills in this
study provided analyzable play observation data,
demonstrating that this method allows autistic children of
all levels of support needs to participate in research and
demonstrate their social, communication, and attention
skills without wearing any devices.},
Doi = {10.1177/13623613231169546},
Key = {fds370900}
}
@article{fds372989,
Author = {Shic, F and Barney, EC and Naples, AJ and Dommer, KJ and Chang, SA and Li,
B and McAllister, T and Atyabi, A and Wang, Q and Bernier, R and Dawson, G and Dziura, J and Faja, S and Jeste, SS and Murias, M and Johnson, SP and Sabatos-DeVito, M and Helleman, G and Senturk, D and Sugar, CA and Webb,
SJ and McPartland, JC and Chawarska, K and Autism Biomarkers
Consortium for Clinical Trials},
Title = {The Selective Social Attention task in children with autism
spectrum disorder: Results from the Autism Biomarkers
Consortium for Clinical Trials (ABC-CT) feasibility
study.},
Journal = {Autism Res},
Volume = {16},
Number = {11},
Pages = {2150-2159},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1002/aur.3026},
Abstract = {The Selective Social Attention (SSA) task is a brief
eye-tracking task involving experimental conditions varying
along socio-communicative axes. Traditionally the SSA has
been used to probe socially-specific attentional patterns in
infants and toddlers who develop autism spectrum disorder
(ASD). This current work extends these findings to preschool
and school-age children. Children 4- to 12-years-old with
ASD (N = 23) and a typically-developing comparison group
(TD; N = 25) completed the SSA task as well as
standardized clinical assessments. Linear mixed models
examined group and condition effects on two outcome
variables: percent of time spent looking at the scene
relative to scene presentation time (%Valid), and percent of
time looking at the face relative to time spent looking at
the scene (%Face). Age and IQ were included as covariates.
Outcome variables' relationships to clinical data were
assessed via correlation analysis. The ASD group, compared
to the TD group, looked less at the scene and focused less
on the actress' face during the most socially-engaging
experimental conditions. Additionally, within the ASD group,
%Face negatively correlated with SRS total T-scores with a
particularly strong negative correlation with the Autistic
Mannerism subscale T-score. These results highlight the
extensibility of the SSA to older children with ASD,
including replication of between-group differences
previously seen in infants and toddlers, as well as its
ability to capture meaningful clinical variation within the
autism spectrum across a wide developmental span inclusive
of preschool and school-aged children. The properties
suggest that the SSA may have broad potential as a biomarker
for ASD.},
Doi = {10.1002/aur.3026},
Key = {fds372989}
}
@article{fds369711,
Author = {Howard, J and Herold, B and Major, S and Leahy, C and Ramseur, K and Franz,
L and Deaver, M and Vermeer, S and Carpenter, KL and Murias, M and Huang,
WA and Dawson, G},
Title = {Associations between executive function and attention
abilities and language and social communication skills in
young autistic children.},
Journal = {Autism},
Volume = {27},
Number = {7},
Pages = {2135-2144},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1177/13623613231154310},
Abstract = {Executive functioning describes a set of cognitive processes
that affect thinking and behavior. Past research has shown
that autistic individuals often have delays in the
acquisition of executive function abilities. Our study
explored how differences in executive function and attention
abilities relate to social abilities and
communication/language in 180 young autistic children. Data
were gathered via caregiver report (questionnaires/interviews)
and an assessment of vocabulary skills. The ability to
sustain attention to a dynamic video was measured via eye
tracking. We found that children with higher levels of
executive function skills demonstrated lower levels of
social pragmatic problems, a measure of having difficulties
in social contexts. Furthermore, children who were able to
sustain their attention longer to the video displayed higher
levels of expressive language. Our results emphasize the
importance of executive function and attention skills across
multiple areas of functioning in autistic children, in
particular those that involve language and social
communication.},
Doi = {10.1177/13623613231154310},
Key = {fds369711}
}
@article{fds373014,
Author = {Perochon, S and Di Martino and JM and Carpenter, KLH and Compton, S and Davis, N and Eichner, B and Espinosa, S and Franz, L and Krishnappa
Babu, PR and Sapiro, G and Dawson, G},
Title = {Early detection of autism using digital behavioral
phenotyping.},
Journal = {Nat Med},
Volume = {29},
Number = {10},
Pages = {2489-2497},
Publisher = {Springer Science and Business Media LLC},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1038/s41591-023-02574-3},
Abstract = {Early detection of autism, a neurodevelopmental condition
associated with challenges in social communication, ensures
timely access to intervention. Autism screening
questionnaires have been shown to have lower accuracy when
used in real-world settings, such as primary care, as
compared to research studies, particularly for children of
color and girls. Here we report findings from a multiclinic,
prospective study assessing the accuracy of an autism
screening digital application (app) administered during a
pediatric well-child visit to 475 (17-36 months old)
children (269 boys and 206 girls), of which 49 were
diagnosed with autism and 98 were diagnosed with
developmental delay without autism. The app displayed
stimuli that elicited behavioral signs of autism, quantified
using computer vision and machine learning. An algorithm
combining multiple digital phenotypes showed high diagnostic
accuracy with the area under the receiver operating
characteristic curve = 0.90, sensitivity = 87.8%,
specificity = 80.8%, negative predictive
value = 97.8% and positive predictive value = 40.6%.
The algorithm had similar sensitivity performance across
subgroups as defined by sex, race and ethnicity. These
results demonstrate the potential for digital phenotyping to
provide an objective, scalable approach to autism screening
in real-world settings. Moreover, combining results from
digital phenotyping and caregiver questionnaires may
increase autism screening accuracy and help reduce
disparities in access to diagnosis and intervention.},
Doi = {10.1038/s41591-023-02574-3},
Key = {fds373014}
}
@misc{fds374977,
Author = {Feibel, AB and DeVito, MS and Carpenter, KLH and Compton, SN and Dawson,
G},
Title = {6.12 Home Video Analysis of Affect and Attention at 12
Months in ASD and ADHD},
Journal = {Journal of the American Academy of Child & Adolescent
Psychiatry},
Volume = {62},
Number = {10},
Pages = {S289-S290},
Publisher = {Elsevier BV},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1016/j.jaac.2023.09.419},
Doi = {10.1016/j.jaac.2023.09.419},
Key = {fds374977}
}
@misc{fds374978,
Author = {Barnes, LB and DeVito, MS and Carpenter, KLH and Compton, SN and Dawson,
G},
Title = {6.3 Early Motor and Communication Indicators of ASD and ADHD
and Prediction of Later Skills Based on Home Video Coding at
12 Months},
Journal = {Journal of the American Academy of Child & Adolescent
Psychiatry},
Volume = {62},
Number = {10},
Pages = {S286-S287},
Publisher = {Elsevier BV},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1016/j.jaac.2023.09.410},
Doi = {10.1016/j.jaac.2023.09.410},
Key = {fds374978}
}
@article{fds373635,
Author = {Franz, L and Viljoen, M and Askew, S and Brown, M and Dawson, G and Di
Martino, JM and Sapiro, G and Sebolai, K and Seris, N and Shabalala, N and Stahmer, A and Turner, EL and de Vries, PJ},
Title = {Autism Caregiver Coaching in Africa (ACACIA): Protocol for a
type 1-hybrid effectiveness-implementation
trial.},
Journal = {medRxiv},
Volume = {19},
Number = {1},
Pages = {e0291883},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1101/2023.09.10.23295331},
Abstract = {BACKGROUND: While early autism intervention can
significantly improve outcomes, gaps in implementation exist
globally. These gaps are clearest in Africa, where forty
percent of the world's children will live by 2050.
Task-sharing early intervention to non-specialists is a key
implementation strategy, given the lack of specialists in
Africa. Naturalistic Developmental Behavioral Interventions
(NDBI) are a class of early autism intervention that can be
delivered by caregivers. As a foundational step to address
the early autism intervention gap, we adapted a
non-specialist delivered caregiver coaching NDBI for the
South African context, and pre-piloted this cascaded
task-sharing approach in an existing system of care.
OBJECTIVES: First, we will test the effectiveness of the
caregiver coaching NDBI compared to usual care. Second, we
will describe coaching implementation factors within the
Western Cape Department of Education in South Africa.
METHODS: This is a type 1 effectiveness-implementation
hybrid design; assessor-blinded, group randomized controlled
trial. Participants include 150 autistic children (18-72
months) and their caregivers who live in Cape Town, South
Africa, and those involved in intervention implementation.
Early Childhood Development practitioners, employed by the
Department of Education, will deliver 12, one hour, coaching
sessions to the intervention group. The control group will
receive usual care. Distal co-primary outcomes include the
Communication Domain Standard Score (Vineland Adaptive
Behavior Scales, Third Edition) and the Language and
Communication Developmental Quotient (Griffiths Scales of
Child Development, Third Edition). Proximal secondary
outcome include caregiver strategies measured by the sum of
five items from the Joint Engagement Rating Inventory. We
will describe key implementation determinants. RESULTS:
Participant enrolment started in April 2023. Estimated
primary completion date is March 2027. CONCLUSION: The
ACACIA trial will determine whether a cascaded task-sharing
intervention delivered in an educational setting leads to
meaningful improvements in communication abilities of
autistic children, and identify implementation barriers and
facilitators.},
Doi = {10.1101/2023.09.10.23295331},
Key = {fds373635}
}
@article{fds372830,
Author = {Dawson, G},
Title = {Could an Eye-Tracking Test Aid Clinicians in Making an
Autism Diagnosis?: New Findings and a Look to the
Future.},
Journal = {JAMA},
Volume = {330},
Number = {9},
Pages = {815-817},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1001/jama.2023.3092},
Doi = {10.1001/jama.2023.3092},
Key = {fds372830}
}
@article{fds372475,
Author = {Bey, AL and Sabatos-DeVito, M and Carpenter, KLH and Franz, L and Howard, J and Vermeer, S and Simmons, R and Troy, JD and Dawson,
G},
Title = {Automated Video Tracking of Autistic Children's Movement
During Caregiver-Child Interaction: An Exploratory
Study.},
Journal = {J Autism Dev Disord},
Publisher = {Springer Science and Business Media LLC},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1007/s10803-023-06107-2},
Abstract = {Objective, quantitative measures of caregiver-child
interaction during play are needed to complement caregiver
or examiner ratings for clinical assessment and tracking
intervention responses. In this exploratory study, we
examined the feasibility of using automated video tracking,
Noldus EthoVision XT, to measure 159 2-to-7-year-old
autistic children's patterns of movement during play-based,
caregiver-child interactions and examined their associations
with standard clinical measures and human observational
coding of caregiver-child joint engagement. Results revealed
that autistic children who exhibited higher durations and
velocity of movement were, on average, younger, had lower
cognitive abilities, greater autism-related features, spent
less time attending to the caregiver, and showed lower
levels of joint engagement. After adjusting for age and
nonverbal cognitive abilities, we found that children who
remained in close proximity to their caregiver were more
likely to engage in joint engagement that required support
from the caregiver. These findings suggest that video
tracking offers promise as a scalable, quantitative, and
relevant measure of autism-related behaviors.},
Doi = {10.1007/s10803-023-06107-2},
Key = {fds372475}
}
@article{fds363734,
Author = {Tsang, T and Naples, AJ and Barney, EC and Xie, M and Bernier, R and Dawson, G and Dziura, J and Faja, S and Jeste, SS and McPartland, JC and Nelson, CA and Murias, M and Seow, H and Sugar, C and Webb, SJ and Shic, F and Johnson, SP},
Title = {Attention Allocation During Exploration of Visual Arrays in
ASD: Results from the ABC-CT Feasibility
Study.},
Journal = {J Autism Dev Disord},
Volume = {53},
Number = {8},
Pages = {3220-3229},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1007/s10803-022-05569-0},
Abstract = {Visual exploration paradigms involving object arrays have
been used to examine salience of social stimuli such as
faces in ASD. Recent work suggests performance on these
paradigms may associate with clinical features of ASD. We
evaluate metrics from a visual exploration paradigm in
4-to-11-year-old children with ASD (n = 23; 18 males)
and typical development (TD; n = 23; 13 males).
Presented with arrays containing faces and nonsocial
stimuli, children with ASD looked less at (p = 0.002)
and showed fewer fixations to (p = 0.022) faces than TD
children, and spent less time looking at each object on
average (p = 0.004). Attention to the screen and faces
correlated positively with social and cognitive skills in
the ASD group (ps < .05). This work furthers our
understanding of objective measures of visual exploration in
ASD and its potential for quantifying features of
ASD.},
Doi = {10.1007/s10803-022-05569-0},
Key = {fds363734}
}
@article{fds371014,
Author = {Chen, J and Engelhard, M and Henao, R and Berchuck, S and Eichner, B and Perrin, EM and Sapiro, G and Dawson, G},
Title = {Enhancing early autism prediction based on electronic
records using clinical narratives.},
Journal = {J Biomed Inform},
Volume = {144},
Pages = {104390},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1016/j.jbi.2023.104390},
Abstract = {Recent work has shown that predictive models can be applied
to structured electronic health record (EHR) data to
stratify autism likelihood from an early age (<1 year).
Integrating clinical narratives (or notes) with structured
data has been shown to improve prediction performance in
other clinical applications, but the added predictive value
of this information in early autism prediction has not yet
been explored. In this study, we aimed to enhance the
performance of early autism prediction by using both
structured EHR data and clinical narratives. We built models
based on structured data and clinical narratives separately,
and then an ensemble model that integrated both sources of
data. We assessed the predictive value of these models from
Duke University Health System over a 14-year span to
evaluate ensemble models predicting later autism diagnosis
(by age 4 years) from data collected from ages 30 to
360 days. Our sample included 11,750 children above by age
3 years (385 meeting autism diagnostic criteria). The
ensemble model for autism prediction showed superior
performance and at age 30 days achieved 46.8% sensitivity
(95% confidence interval, CI: 22.0%, 52.9%), 28.0% positive
predictive value (PPV) at high (90%) specificity (CI: 2.0%,
33.1%), and AUC4 (with at least 4-year follow-up for
controls) reaching 0.769 (CI: 0.715, 0.811). Prediction by
360 days achieved 44.5% sensitivity (CI: 23.6%, 62.9%),
and 13.7% PPV at high (90%) specificity (CI: 9.6%, 18.9%),
and AUC4 reaching 0.797 (CI: 0.746, 0.840). Results show
that incorporating clinical narratives in early autism
prediction achieved promising accuracy by age 30 days,
outperforming models based on structured data only.
Furthermore, findings suggest that additional features
learned from clinician narratives might be hypothesis
generating for understanding early development in
autism.},
Doi = {10.1016/j.jbi.2023.104390},
Key = {fds371014}
}
@article{fds371094,
Author = {Coffman, M and Di Martino and JM and Aiello, R and Carpenter, KLH and Chang, Z and Compton, S and Eichner, B and Espinosa, S and Flowers, J and Franz, L and Perochon, S and Krishnappa Babu and PR and Sapiro, G and Dawson, G},
Title = {Relationship between quantitative digital behavioral
features and clinical profiles in young autistic
children.},
Journal = {Autism Res},
Volume = {16},
Number = {7},
Pages = {1360-1374},
Publisher = {WILEY},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1002/aur.2955},
Abstract = {Early behavioral markers for autism include differences in
social attention and orienting in response to one's name
when called, and differences in body movements and motor
abilities. More efficient, scalable, objective, and reliable
measures of these behaviors could improve early screening
for autism. This study evaluated whether objective and
quantitative measures of autism-related behaviors elicited
from an app (SenseToKnow) administered on a smartphone or
tablet and measured via computer vision analysis (CVA) are
correlated with standardized caregiver-report and clinician
administered measures of autism-related behaviors and
cognitive, language, and motor abilities. This is an
essential step in establishing the concurrent validity of a
digital phenotyping approach. In a sample of 485 toddlers,
43 of whom were diagnosed with autism, we found that
CVA-based gaze variables related to social attention were
associated with the level of autism-related behaviors. Two
language-related behaviors measured via the app, attention
to people during a conversation and responding to one's name
being called, were associated with children's language
skills. Finally, performance during a bubble popping game
was associated with fine motor skills. These findings
provide initial support for the concurrent validity of the
SenseToKnow app and its potential utility in identifying
clinical profiles associated with autism. Future research is
needed to determine whether the app can be used as an autism
screening tool, can reliably stratify autism-related
behaviors, and measure changes in autism-related behaviors
over time.},
Doi = {10.1002/aur.2955},
Key = {fds371094}
}
@article{fds370636,
Author = {Krishnappa Babu and PR and Aikat, V and Di Martino and JM and Chang, Z and Perochon, S and Espinosa, S and Aiello, R and L H Carpenter and K and Compton, S and Davis, N and Eichner, B and Flowers, J and Franz, L and Dawson, G and Sapiro, G},
Title = {Blink rate and facial orientation reveal distinctive
patterns of attentional engagement in autistic toddlers: a
digital phenotyping approach.},
Journal = {Sci Rep},
Volume = {13},
Number = {1},
Pages = {7158},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1038/s41598-023-34293-7},
Abstract = {Differences in social attention are well-documented in
autistic individuals, representing one of the earliest signs
of autism. Spontaneous blink rate has been used to index
attentional engagement, with lower blink rates reflecting
increased engagement. We evaluated novel methods using
computer vision analysis (CVA) for automatically quantifying
patterns of attentional engagement in young autistic
children, based on facial orientation and blink rate, which
were captured via mobile devices. Participants were 474
children (17-36 months old), 43 of whom were diagnosed with
autism. Movies containing social or nonsocial content were
presented via an iPad app, and simultaneously, the device's
camera recorded the children's behavior while they watched
the movies. CVA was used to extract the duration of time the
child oriented towards the screen and their blink rate as
indices of attentional engagement. Overall, autistic
children spent less time facing the screen and had a higher
mean blink rate compared to neurotypical children.
Neurotypical children faced the screen more often and
blinked at a lower rate during the social movies compared to
the nonsocial movies. In contrast, autistic children faced
the screen less often during social movies than during
nonsocial movies and showed no differential blink rate to
social versus nonsocial movies.},
Doi = {10.1038/s41598-023-34293-7},
Key = {fds370636}
}
@article{fds367086,
Author = {Shurtz, L and Schwartz, C and DiStefano, C and McPartland, JC and Levin,
AR and Dawson, G and Kleinhans, NM and Faja, S and Webb, SJ and Shic, F and Naples, AJ and Seow, H and Bernier, RA and Chawarska, K and Sugar, CA and Dziura, J and Senturk, D and Santhosh, M and Jeste,
SS},
Title = {Concomitant medication use in children with autism spectrum
disorder: Data from the Autism Biomarkers Consortium for
Clinical Trials.},
Journal = {Autism},
Volume = {27},
Number = {4},
Pages = {952-966},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1177/13623613221121425},
Abstract = {Children with autism spectrum disorder are prescribed a
variety of medications that affect the central nervous
system (psychotropic medications) to address behavior and
mood. In clinical trials, individuals taking concomitant
psychotropic medications often are excluded to maintain
homogeneity of the sample and prevent contamination of
biomarkers or clinical endpoints. However, this choice may
significantly diminish the clinical representativeness of
the sample. In a recent multisite study designed to identify
biomarkers and behavioral endpoints for clinical trials (the
Autism Biomarkers Consortium for Clinical Trials),
school-age children with autism spectrum disorder were
enrolled without excluding for medications, thus providing a
unique opportunity to examine characteristics of
psychotropic medication use in a research cohort and to
guide future decisions on medication-related inclusion
criteria. The aims of the current analysis were (1) to
quantify the frequency and type of psychotropic medications
reported in school-age children enrolled in the ABC-CT and
(2) to examine behavioral features of children with autism
spectrum disorder based on medication classes. Of the 280
children with autism spectrum disorder in the cohort, 42.5%
were taking psychotropic medications, with polypharmacy in
half of these children. The most commonly reported
psychotropic medications included melatonin, stimulants,
selective serotonin reuptake inhibitors, alpha agonists, and
antipsychotics. Descriptive analysis showed that children
taking antipsychotics displayed a trend toward greater
overall impairment. Our findings suggest that exclusion of
children taking concomitant psychotropic medications in
trials could limit the clinical representativeness of the
study population, perhaps even excluding children who may
most benefit from new treatment options.},
Doi = {10.1177/13623613221121425},
Key = {fds367086}
}
@article{fds370254,
Author = {Wall, CA and Sabatos-DeVito, M and Franz, L and Howard, J and Major, S and Bey, A and Dawson, G},
Title = {Eye-tracking measures of social versus nonsocial attention
are related to level of social engagement during
naturalistic caregiver-child interactions in autistic
children.},
Journal = {Autism Res},
Volume = {16},
Number = {5},
Pages = {1052-1062},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1002/aur.2920},
Abstract = {Eye-tracking (ET) measures indexing social attention have
been proposed as sensitive measures related to autism, but
less is known about the relationship between social and
nonsocial attention and naturalistic measures of social
engagement and whether sex moderates this relationship. This
study investigated ET measures of social attention as
predictors of social engagement during a naturalistic
caregiver-child interaction (CCI). Participants included
132, 2-7-year-old autistic children (77% male) and their
caregivers. Participants engaged in a CCI and an ET task in
which they viewed a video of an actor making dyadic bids
toward the child with toys in the background. Pearson
correlations and multiple regression analyzes revealed that
ET measures correlated with social engagement behaviors,
including degree of attention to the caregiver and objects,
joint engagement with the caregiver, and language-based
joint engagement. Children who spent more time looking at
toys were more likely to be unengaged during social
interaction. Those who spent more time looking at the
actor's mouth were more likely to engage in coordinated play
with and without language. Sex moderated the relationship
between time looking at toys and unengagement during play;
males who spent more time looking at toys spent more time
unengaged during play, whereas females who spent more time
looking at toys spent less time unengaged during play.
Overall, ET measures of social and nonsocial attention
correlated with the level of social engagement during
naturalistic play, with some sex differences. Eye-tracking
measures that predict interaction patterns may provide
insight into promoting social engagement between caregivers
and their autistic children and can inform outcome
monitoring and intervention development.},
Doi = {10.1002/aur.2920},
Key = {fds370254}
}
@article{fds370255,
Author = {Faja, S and Sabatos-DeVito, M and Sridhar, A and Kuhn, JL and Nikolaeva,
JI and Sugar, CA and Webb, SJ and Bernier, RA and Sikich, L and Hellemann,
G and Senturk, D and Naples, AJ and Shic, F and Levin, AR and Seow, HA and Dziura, JD and Jeste, SS and Chawarska, K and Nelson, CA and Dawson, G and McPartland, JC and Autism Biomarkers Consortium for Clinical
Trials},
Title = {Evaluation of clinical assessments of social abilities for
use in autism clinical trials by the autism biomarkers
consortium for clinical trials.},
Journal = {Autism Res},
Volume = {16},
Number = {5},
Pages = {981-996},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1002/aur.2905},
Abstract = {Clinical trials in autism spectrum disorder (ASD) often rely
on clinician rating scales and parent surveys to measure
autism-related features and social behaviors. To aid in the
selection of these assessments for future clinical trials,
the Autism Biomarkers Consortium for Clinical Trials
(ABC-CT) directly compared eight common instruments with
respect to acquisition rates, sensitivity to group
differences, equivalence across demographic sub-groups,
convergent validity, and stability over a 6-week period. The
sample included 280 children diagnosed with ASD (65 girls)
and 119 neurotypical children (36 girls) aged from 6 to
11 years. Full scale IQ for ASD ranged from 60 to 150 and
for neurotypical ranged from 86 to 150. Instruments measured
clinician global assessment and autism-related behaviors,
social communication abilities, adaptive function, and
social withdrawal behavior. For each instrument, we examined
only the scales that measured social or communication
functioning. Data acquisition rates were at least 97.5% at
T1 and 95.7% at T2. All scales distinguished diagnostic
groups. Some scales significantly differed by participant
and/or family demographic characteristics. Within the ASD
group, most clinical instruments exhibited weak (≥ |0.1|)
to moderate (≥ |0.4|) intercorrelations. Short-term
stability was moderate (ICC: 0.5-0.75) to excellent (ICC:
>0.9) within the ASD group. Variations in the degree of
stability may inform viability for different contexts of
use, such as identifying clinical subgroups for trials
versus serving as a modifiable clinical outcome. All
instruments were evaluated in terms of their advantages and
potential concerns for use in clinical trials.},
Doi = {10.1002/aur.2905},
Key = {fds370255}
}
@article{fds370523,
Author = {Isaev, DY and Sabatos-DeVito, M and Di Martino and JM and Carpenter, K and Aiello, R and Compton, S and Davis, N and Franz, L and Sullivan, C and Dawson, G and Sapiro, G},
Title = {Computer Vision Analysis of Caregiver-Child Interactions in
Children with Neurodevelopmental Disorders: A Preliminary
Report.},
Journal = {J Autism Dev Disord},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1007/s10803-023-05973-0},
Abstract = {We report preliminary results of computer vision analysis of
caregiver-child interactions during free play with children
diagnosed with autism (N = 29, 41-91 months),
attention-deficit/hyperactivity disorder (ADHD, N = 22,
48-100 months), or combined autism + ADHD (N = 20,
56-98 months), and neurotypical children (NT, N = 7,
55-95 months). We conducted micro-analytic analysis of
'reaching to a toy,' as a proxy for initiating or responding
to a toy play bout. Dyadic analysis revealed two clusters of
interaction patterns, which differed in frequency of
'reaching to a toy' and caregivers' contingent responding to
the child's reach for a toy by also reaching for a toy.
Children in dyads with higher caregiver responsiveness had
less developed language, communication, and socialization
skills. Clusters were not associated with diagnostic groups.
These results hold promise for automated methods of
characterizing caregiver responsiveness in dyadic
interactions for assessment and outcome monitoring in
clinical trials.},
Doi = {10.1007/s10803-023-05973-0},
Key = {fds370523}
}
@article{fds366205,
Author = {Dong, M and Telesca, D and Sugar, C and Shic, F and Naples, A and Johnson,
SP and Li, B and Atyabi, A and Xie, M and Webb, SJ and Jeste, S and Faja, S and Levin, AR and Dawson, G and McPartland, JC and Şentürk, D and Autism
Biomarkers Consortium for Clinical Trials},
Title = {A functional model for studying common trends across trial
time in eye tracking experiments.},
Journal = {Statistics in biosciences},
Volume = {15},
Number = {1},
Pages = {261-287},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1007/s12561-022-09354-6},
Abstract = {Eye tracking (ET) experiments commonly record the continuous
trajectory of a subject's gaze on a two-dimensional screen
throughout repeated presentations of stimuli (referred to as
trials). Even though the continuous path of gaze is recorded
during each trial, commonly derived outcomes for analysis
collapse the data into simple summaries, such as looking
times in regions of interest, latency to looking at stimuli,
number of stimuli viewed, number of fixations or fixation
length. In order to retain information in trial time, we
utilize functional data analysis (FDA) for the first time in
literature in the analysis of ET data. More specifically,
novel functional outcomes for ET data, referred to as
viewing profiles, are introduced that capture the common
gazing trends across trial time which are lost in
traditional data summaries. Mean and variation of the
proposed functional outcomes across subjects are then
modeled using functional principal components analysis.
Applications to data from a visual exploration paradigm
conducted by the Autism Biomarkers Consortium for Clinical
Trials showcase the novel insights gained from the proposed
FDA approach, including significant group differences
between children diagnosed with autism and their typically
developing peers in their consistency of looking at faces
early on in trial time.},
Doi = {10.1007/s12561-022-09354-6},
Key = {fds366205}
}
@article{fds367885,
Author = {Dawson, G and Rieder, AD and Johnson, MH},
Title = {Prediction of autism in infants: progress and
challenges.},
Journal = {Lancet Neurol},
Volume = {22},
Number = {3},
Pages = {244-254},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1016/S1474-4422(22)00407-0},
Abstract = {Autism spectrum disorder (henceforth autism) is a
neurodevelopmental condition that can be reliably diagnosed
in children by age 18-24 months. Prospective longitudinal
studies of infants aged 1 year and younger who are later
diagnosed with autism are elucidating the early
developmental course of autism and identifying ways of
predicting autism before diagnosis is possible. Studies that
use MRI, EEG, and near-infrared spectroscopy have identified
differences in brain development in infants later diagnosed
with autism compared with infants without autism.
Retrospective studies of infants younger than 1 year who
received a later diagnosis of autism have also showed an
increased prevalence of health conditions, such as sleep
disorders, gastrointestinal disorders, and vision problems.
Behavioural features of infants later diagnosed with autism
include differences in attention, vocalisations, gestures,
affect, temperament, social engagement, sensory processing,
and motor abilities. Although research findings offer
insight on promising screening approaches for predicting
autism in infants, individual-level predictions remain a
future goal. Multiple scientific challenges and ethical
questions remain to be addressed to translate research on
early brain-based and behavioural predictors of autism into
feasible and reliable screening tools for clinical
practice.},
Doi = {10.1016/S1474-4422(22)00407-0},
Key = {fds367885}
}
@article{fds369254,
Author = {Perochon, S and Matias Di Martino and J and Carpenter, KLH and Compton,
S and Davis, N and Espinosa, S and Franz, L and Rieder, AD and Sullivan, C and Sapiro, G and Dawson, G},
Title = {A tablet-based game for the assessment of visual motor
skills in autistic children.},
Journal = {NPJ Digit Med},
Volume = {6},
Number = {1},
Pages = {17},
Publisher = {Springer Science and Business Media LLC},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1038/s41746-023-00762-6},
Abstract = {Increasing evidence suggests that early motor impairments
are a common feature of autism. Thus, scalable, quantitative
methods for measuring motor behavior in young autistic
children are needed. This work presents an engaging and
scalable assessment of visual-motor abilities based on a
bubble-popping game administered on a tablet. Participants
are 233 children ranging from 1.5 to 10 years of age (147
neurotypical children and 86 children diagnosed with autism
spectrum disorder [autistic], of which 32 are also diagnosed
with co-occurring attention-deficit/hyperactivity disorder
[autistic+ADHD]). Computer vision analyses are used to
extract several game-based touch features, which are
compared across autistic, autistic+ADHD, and neurotypical
participants. Results show that younger (1.5-3 years)
autistic children pop the bubbles at a lower rate, and their
ability to touch the bubble's center is less accurate
compared to neurotypical children. When they pop a bubble,
their finger lingers for a longer period, and they show more
variability in their performance. In older children
(3-10-years), consistent with previous research, the
presence of co-occurring ADHD is associated with greater
motor impairment, reflected in lower accuracy and more
variable performance. Several motor features are correlated
with standardized assessments of fine motor and cognitive
abilities, as evaluated by an independent clinical
assessment. These results highlight the potential of
touch-based games as an efficient and scalable approach for
assessing children's visual-motor skills, which can be part
of a broader screening tool for identifying early signs
associated with autism.},
Doi = {10.1038/s41746-023-00762-6},
Key = {fds369254}
}
@article{fds369360,
Author = {Engelhard, MM and Henao, R and Berchuck, SI and Chen, J and Eichner, B and Herkert, D and Kollins, SH and Olson, A and Perrin, EM and Rogers, U and Sullivan, C and Zhu, Y and Sapiro, G and Dawson, G},
Title = {Predictive Value of Early Autism Detection Models Based on
Electronic Health Record Data Collected Before Age 1
Year.},
Journal = {JAMA Netw Open},
Volume = {6},
Number = {2},
Pages = {e2254303},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1001/jamanetworkopen.2022.54303},
Abstract = {IMPORTANCE: Autism detection early in childhood is critical
to ensure that autistic children and their families have
access to early behavioral support. Early correlates of
autism documented in electronic health records (EHRs) during
routine care could allow passive, predictive model-based
monitoring to improve the accuracy of early detection.
OBJECTIVE: To quantify the predictive value of early autism
detection models based on EHR data collected before age 1
year. DESIGN, SETTING, AND PARTICIPANTS: This retrospective
diagnostic study used EHR data from children seen within the
Duke University Health System before age 30 days between
January 2006 and December 2020. These data were used to
train and evaluate L2-regularized Cox proportional hazards
models predicting later autism diagnosis based on data
collected from birth up to the time of prediction (ages
30-360 days). Statistical analyses were performed between
August 1, 2020, and April 1, 2022. MAIN OUTCOMES AND
MEASURES: Prediction performance was quantified in terms of
sensitivity, specificity, and positive predictive value
(PPV) at clinically relevant model operating thresholds.
RESULTS: Data from 45 080 children, including 924 (1.5%)
meeting autism criteria, were included in this study.
Model-based autism detection at age 30 days achieved 45.5%
sensitivity and 23.0% PPV at 90.0% specificity. Detection by
age 360 days achieved 59.8% sensitivity and 17.6% PPV at
81.5% specificity and 38.8% sensitivity and 31.0% PPV at
94.3% specificity. CONCLUSIONS AND RELEVANCE: In this
diagnostic study of an autism screening test, EHR-based
autism detection achieved clinically meaningful accuracy by
age 30 days, improving by age 1 year. This automated
approach could be integrated with caregiver surveys to
improve the accuracy of early autism screening.},
Doi = {10.1001/jamanetworkopen.2022.54303},
Key = {fds369360}
}
@article{fds365562,
Author = {Krishnappa Babu and PR and Di Martino and JM and Chang, Z and Perochon, S and Aiello, R and Carpenter, KLH and Compton, S and Davis, N and Franz, L and Espinosa, S and Flowers, J and Dawson, G and Sapiro,
G},
Title = {Complexity analysis of head movements in autistic
toddlers.},
Journal = {J Child Psychol Psychiatry},
Volume = {64},
Number = {1},
Pages = {156-166},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1111/jcpp.13681},
Abstract = {BACKGROUND: Early differences in sensorimotor functioning
have been documented in young autistic children and infants
who are later diagnosed with autism. Previous research has
demonstrated that autistic toddlers exhibit more frequent
head movement when viewing dynamic audiovisual stimuli,
compared to neurotypical toddlers. To further explore this
behavioral characteristic, in this study, computer vision
(CV) analysis was used to measure several aspects of head
movement dynamics of autistic and neurotypical toddlers
while they watched a set of brief movies with social and
nonsocial content presented on a tablet. METHODS: Data were
collected from 457 toddlers, 17-36 months old, during
their well-child visit to four pediatric primary care
clinics. Forty-one toddlers were subsequently diagnosed with
autism. An application (app) displayed several brief movies
on a tablet, and the toddlers watched these movies while
sitting on their caregiver's lap. The front-facing camera in
the tablet recorded the toddlers' behavioral responses. CV
was used to measure the participants' head movement rate,
movement acceleration, and complexity using multiscale
entropy. RESULTS: Autistic toddlers exhibited significantly
higher rate, acceleration, and complexity in their head
movements while watching the movies compared to neurotypical
toddlers, regardless of the type of movie content (social
vs. nonsocial). The combined features of head movement
acceleration and complexity reliably distinguished the
autistic and neurotypical toddlers. CONCLUSIONS: Autistic
toddlers exhibit differences in their head movement dynamics
when viewing audiovisual stimuli. Higher complexity of their
head movements suggests that their movements were less
predictable and less stable compared to neurotypical
toddlers. CV offers a scalable means of detecting subtle
differences in head movement dynamics, which may be helpful
in identifying early behaviors associated with autism and
providing insight into the nature of sensorimotor
differences associated with autism.},
Doi = {10.1111/jcpp.13681},
Key = {fds365562}
}
@article{fds367087,
Author = {Webb, SJ and Naples, AJ and Levin, AR and Hellemann, G and Borland, H and Benton, J and Carlos, C and McAllister, T and Santhosh, M and Seow, H and Atyabi, A and Bernier, R and Chawarska, K and Dawson, G and Dziura, J and Faja, S and Jeste, S and Murias, M and Nelson, CA and Sabatos-DeVito, M and Senturk, D and Shic, F and Sugar, CA and McPartland,
JC},
Title = {The Autism Biomarkers Consortium for Clinical Trials:
Initial Evaluation of a Battery of Candidate EEG
Biomarkers.},
Journal = {Am J Psychiatry},
Volume = {180},
Number = {1},
Pages = {41-49},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1176/appi.ajp.21050485},
Abstract = {OBJECTIVE: Numerous candidate EEG biomarkers have been put
forward for use in clinical research on autism spectrum
disorder (ASD), but biomarker development has been hindered
by limited attention to the psychometric properties of
derived variables, inconsistent results across small
studies, and variable methodology. The authors evaluated the
basic psychometric properties of a battery of EEG assays for
their potential suitability as biomarkers in clinical
trials. METHODS: This was a large, multisite, naturalistic
study in 6- to 11-year-old children who either had an ASD
diagnosis (N=280) or were typically developing (N=119). The
authors evaluated an EEG battery composed of well-studied
assays of resting-state activity, face perception (faces
task), biological motion perception, and visual evoked
potentials (VEPs). Biomarker psychometrics were evaluated in
terms of acquisition rates, construct performance, and
6-week stability. Preliminary evaluation of use was explored
through group discrimination and phenotypic correlations.
RESULTS: Three assays (resting state, faces task, and VEP)
show promise in terms of acquisition rates and construct
performance. Six-week stability values in the ASD group were
moderate (intraclass correlations ≥0.66) for the faces
task latency of the P1 and N170, the VEP amplitude of N1 and
P1, and resting alpha power. Group discrimination and
phenotype correlations were primarily observed for the faces
task P1 and N170. CONCLUSIONS: In the context of a
large-scale, rigorous evaluation of candidate EEG biomarkers
for use in ASD clinical trials, neural response to faces
emerged as a promising biomarker for continued evaluation.
Resting-state activity and VEP yielded mixed results. The
study's biological motion perception assay failed to display
construct performance. The results provide information about
EEG biomarker performance that is relevant for the next
stage of biomarker development efforts focused on context of
use.},
Doi = {10.1176/appi.ajp.21050485},
Key = {fds367087}
}
@article{fds374238,
Author = {Kwan, B and Sugar, CA and Qian, Q and Shic, F and Naples, A and Johnson,
SP and Webb, SJ and Jeste, S and Faja, S and Levin, AR and Dawson, G and McPartland, JC and Şentürk, D},
Title = {Constrained Multivariate Functional Principal Components
Analysis for Novel Outcomes in Eye-Tracking
Experiments},
Journal = {Statistics in Biosciences},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1007/s12561-023-09399-1},
Abstract = {Individuals with autism spectrum disorder (ASD) tend to
experience greater difficulties with social communication
and sensory information processing. Of particular interest
in ASD biomarker research is the study of visual attention,
effectively quantified in eye tracking (ET) experiments. Eye
tracking offers a powerful, safe, and feasible platform for
gaining insights into attentional processes by measuring
moment-by-moment gaze patterns in response to stimuli. Even
though recording is done with millisecond granularity,
analyses commonly collapse data across trials into variables
such as proportion time spent looking at a region of
interest (ROI). In addition, looking times in different ROIs
are typically analyzed separately. We propose a novel
multivariate functional outcome that carries proportion
looking time information from multiple regions of interest
jointly as a function of trial type, along with a novel
constrained multivariate functional principal components
analysis procedure to capture the variation in this outcome.
The method incorporates the natural constraint that the
proportion looking times from the multiple regions of
interest must sum up to one. Our approach is motivated by
the Activity Monitoring task, a social-attentional assay
within the ET battery of the Autism Biomarkers Consortium
for Clinical Trials (ABC-CT). Application of our methods to
the ABC-CT data yields new insights into dominant modes of
variation of proportion looking times from multiple regions
of interest for school-age children with ASD and their
typically developing (TD) peers, as well as richer analysis
of diagnostic group differences in social
attention.},
Doi = {10.1007/s12561-023-09399-1},
Key = {fds374238}
}
@article{fds359477,
Author = {Babu, PRK and Di Martino and JM and Chang, Z and Perochon, S and Carpenter,
KLH and Compton, S and Espinosa, S and Dawson, G and Sapiro,
G},
Title = {Exploring Complexity of Facial Dynamics in Autism Spectrum
Disorder.},
Journal = {IEEE Trans Affect Comput},
Volume = {14},
Number = {2},
Pages = {919-930},
Year = {2023},
url = {http://dx.doi.org/10.1109/taffc.2021.3113876},
Abstract = {Atypical facial expression is one of the early symptoms of
autism spectrum disorder (ASD) characterized by reduced
regularity and lack of coordination of facial movements.
Automatic quantification of these behaviors can offer novel
biomarkers for screening, diagnosis, and treatment
monitoring of ASD. In this work, 40 toddlers with ASD and
396 typically developing toddlers were shown
developmentally-appropriate and engaging movies presented on
a smart tablet during a well-child pediatric visit. The
movies consisted of social and non-social dynamic scenes
designed to evoke certain behavioral and affective
responses. The front-facing camera of the tablet was used to
capture the toddlers' face. Facial landmarks' dynamics were
then automatically computed using computer vision
algorithms. Subsequently, the complexity of the landmarks'
dynamics was estimated for the eyebrows and mouth regions
using multiscale entropy. Compared to typically developing
toddlers, toddlers with ASD showed higher complexity (i.e.,
less predictability) in these landmarks' dynamics. This
complexity in facial dynamics contained novel information
not captured by traditional facial affect analyses. These
results suggest that computer vision analysis of facial
landmark movements is a promising approach for detecting and
quantifying early behavioral symptoms associated with
ASD.},
Doi = {10.1109/taffc.2021.3113876},
Key = {fds359477}
}
%% De Brigard, Felipe
@article{fds376061,
Author = {Niemi, L and Washington, N and Workman, C and Arcila-Valenzuela, M and De Brigard and F},
Title = {The emotional impact of baseless discrediting of knowledge:
An empirical investigation of epistemic injustice.},
Journal = {Acta psychologica},
Volume = {244},
Pages = {104157},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1016/j.actpsy.2024.104157},
Abstract = {According to theoretical work on epistemic injustice,
baseless discrediting of the knowledge of people with
marginalized social identities is a central driver of
prejudice and discrimination. Discrediting of knowledge may
sometimes be subtle, but it is pernicious, inducing chronic
stress and coping strategies such as emotional avoidance. In
this research, we sought to deepen the understanding of
epistemic injustice's impact by examining emotional
responses to being discredited and assessing if marginalized
social group membership predicts these responses. We
conducted a novel series of three experiments (Total
N = 1690) in which participants (1) shared their factual
knowledge about how a game worked or their personal feelings
about the game; (2) received discrediting feedback
(invalidating remarks), validating feedback (affirming
remarks), or insulting feedback (general negative social
evaluation); and then (3) reported their affect. In all
three studies, on average, affective responses to
discrediting feedback were less negative than to insulting
feedback, and more negative than to validating feedback.
Participants who shared their knowledge reported more
negative affect after discrediting feedback than
participants who shared their feelings. There were
consistent individual differences, including a
twice-replicated finding of reduced negative affect after
receiving discrediting and insulting feedback for Black men
compared to White men and women and Black women. Black men's
race-based traumatic symptom scores predicted their
affective responses to discrediting and insulting feedback,
suggesting that experience with discrimination contributed
to the emotional processing of a key aspect of epistemic
injustice: remarks conveying baseless discrediting of
knowledge.},
Doi = {10.1016/j.actpsy.2024.104157},
Key = {fds376061}
}
@article{fds376898,
Author = {Krasich, K and O'Neill, K and De Brigard and F},
Title = {Looking at Mental Images: Eye-Tracking Mental Simulation
During Retrospective Causal Judgment.},
Journal = {Cognitive science},
Volume = {48},
Number = {3},
Pages = {e13426},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1111/cogs.13426},
Abstract = {How do people evaluate causal relationships? Do they just
consider what actually happened, or do they also consider
what could have counterfactually happened? Using eye
tracking and Gaussian process modeling, we investigated how
people mentally simulated past events to judge what caused
the outcomes to occur. Participants played a virtual
ball-shooting game and then-while looking at a blank
screen-mentally simulated (a) what actually happened, (b)
what counterfactually could have happened, or (c) what
caused the outcome to happen. Our findings showed that
participants moved their eyes in patterns consistent with
the actual or counterfactual events that they mentally
simulated. When simulating what caused the outcome to occur,
participants moved their eyes consistent with simulations of
counterfactual possibilities. These results favor
counterfactual theories of causal reasoning, demonstrate how
eye movements can reflect simulation during this reasoning
and provide a novel approach for investigating retrospective
causal reasoning and counterfactual thinking.},
Doi = {10.1111/cogs.13426},
Key = {fds376898}
}
@article{fds373975,
Author = {Krasich, K and O'Neill, K and Murray, S and Brockmole, JR and De
Brigard, F and Nuthmann, A},
Title = {A computational modeling approach to investigating mind
wandering-related adjustments to gaze behavior during scene
viewing.},
Journal = {Cognition},
Volume = {242},
Pages = {105624},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.cognition.2023.105624},
Abstract = {Research on gaze control has long shown that increased
visual-cognitive processing demands in scene viewing are
associated with longer fixation durations. More recently,
though, longer durations have also been linked to mind
wandering, a perceptually decoupled state of attention
marked by decreased visual-cognitive processing. Toward
better understanding the relationship between fixation
durations and visual-cognitive processing, we ran
simulations using an established random-walk model for
saccade timing and programming and assessed which model
parameters best predicted modulations in fixation durations
associated with mind wandering compared to attentive
viewing. Mind wandering-related fixation durations were best
described as an increase in the variability of the
fixation-generating process, leading to more
variable-sometimes very long-durations. In contrast, past
research showed that increased processing demands increased
the mean duration of the fixation-generating process. The
findings thus illustrate that mind wandering and processing
demands modulate fixation durations through different
mechanisms in scene viewing. This suggests that processing
demands cannot be inferred from changes in fixation
durations without understanding the underlying mechanism by
which these changes were generated.},
Doi = {10.1016/j.cognition.2023.105624},
Key = {fds373975}
}
@article{fds373542,
Author = {Miceli, K and Morales-Torres, R and Khoudary, A and Faul, L and Parikh,
N and De Brigard and F},
Title = {Perceived plausibility modulates hippocampal activity in
episodic counterfactual thinking.},
Journal = {Hippocampus},
Volume = {34},
Number = {1},
Pages = {2-6},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1002/hipo.23583},
Abstract = {Episodic counterfactual thinking (ECT) consists of imagining
alternative outcomes to past personal events. Previous
research has shown that ECT shares common neural substrates
with episodic future thinking (EFT): our ability to imagine
possible future events. Both ECT and EFT have been shown to
critically depend on the hippocampus, and past research has
explored hippocampal engagement as a function of the
perceived plausibility of an imagined future event. However,
the extent to which the hippocampus is modulated by
perceived plausibility during ECT is unknown. In this study,
we combine two functional magnetic resonance imaging
datasets to investigate whether perceived plausibility
modulates hippocampal activity during ECT. Our results
indicate that plausibility parametrically modulates
hippocampal activity during ECT, and that such modulation is
confined to the left anterior portion of the hippocampus.
Moreover, our results indicate that this modulation is
positive, such that increased activity in the left anterior
hippocampus is associated with higher ratings of ECT
plausibility. We suggest that neither effort nor difficulty
alone can account for these results, and instead suggest
possible alternatives to explain the role of the hippocampus
during the construction of plausible and implausible
ECT.},
Doi = {10.1002/hipo.23583},
Key = {fds373542}
}
@article{fds374206,
Author = {Morales-Torres, R and De Brigard and F},
Title = {On the frequency and nature of the cues that elicit déjà
vu and involuntary autobiographical memories.},
Journal = {The Behavioral and brain sciences},
Volume = {46},
Pages = {e370},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1017/s0140525x23000134},
Abstract = {Barzykowski and Moulin suggest that déjà vu and
involuntary autobiographical memories recruit similar
retrieval processes. Here, we invite the authors to clarify
three issues: (1) What mechanism prevents déjà vu to
happen more frequently? (2) What is the role of semantic
cues in involuntary autobiographical retrieval? and (3) How
déjà vu relates to non-believed memories?},
Doi = {10.1017/s0140525x23000134},
Key = {fds374206}
}
@article{fds369853,
Author = {Murray, S and Bermúdez, JP and De Brigard and F},
Title = {Moralization and self-control strategy selection.},
Journal = {Psychonomic bulletin & review},
Volume = {30},
Number = {4},
Pages = {1586-1595},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.3758/s13423-023-02257-7},
Abstract = {To manage conflicts between temptation and commitment,
people use self-control. The process model of self-control
outlines different strategies for managing the onset and
experience of temptation. However, little is known about the
decision-making factors underlying strategy selection.
Across three experiments (N = 317), we tested whether the
moral valence of a commitment predicts how people advise
attentional self-control strategies. In Experiments 1 and 2,
people rated attentional focus strategies as significantly
more effective for people tempted to break moral relative to
immoral commitments, even when controlling for perceived
temptation and trait self-control. Experiment 3 showed that
as people perceived commitments to have more positive moral
valence, they judged attentional focus strategies to be
significantly more effective relative to attentional
distraction strategies. Moreover, this effect was partly
mediated by perceived differences in motivation. These
results indicate that moralization informs decision-making
processes related to self-control strategy
selection.},
Doi = {10.3758/s13423-023-02257-7},
Key = {fds369853}
}
@article{fds371448,
Author = {De Brigard and F},
Title = {"Repressed Memory" Makes No Sense.},
Journal = {Topics in cognitive science},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1111/tops.12677},
Abstract = {The expression "repressed memory" was introduced over 100
years ago as a theoretical term purportedly referring to an
unobservable psychological entity postulated by Freud's
seduction theory. That theory, however, and its hypothesized
cognitive architecture, have been thoroughly debunked-yet
the term "repressed memory" seems to remain. In this paper,
I offer a philosophical evaluation of the meaning of this
theoretical term as well as an argument to question its
scientific status by comparing it to other cases of
theoretical terms that have either survived scientific
change-such as "atom" or "gene"-or that have perished, such
as "black bile." Ultimately, I argue that "repressed memory"
is more like "black bile" than "atom" or "gene" and, thus,
recommend its demotion from our scientific
vocabulary.},
Doi = {10.1111/tops.12677},
Key = {fds371448}
}
@article{fds369341,
Author = {Boone, T and Van Rooy and N and De Brigard and F},
Title = {Not Every Thing Must Go.},
Journal = {Journal of cognitive neuroscience},
Volume = {35},
Number = {3},
Pages = {376-379},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1162/jocn_a_01931},
Abstract = {In The Entangled Brain, Pessoa criticizes standard
approaches in cognitive neuroscience in which the brain is
seen as a functionally decomposable, modular system with
causal operations built up hierarchically. Instead, he
advocates for an emergentist perspective whereby dynamic
brain networks are associated, not with traditional
psychological categories, but with behavioral functions
characterized in evolutionary terms. Here, we raise a number
of concerns with such a radical approach. We ultimately
believe that although much revision to cognitive
neuroscience is welcome and needed, Pessoa's more radical
proposals may be counterproductive.},
Doi = {10.1162/jocn_a_01931},
Key = {fds369341}
}
@article{fds365621,
Author = {Murray, S and Krasich, K and Irving, Z and Nadelhoffer, T and De
Brigard, F},
Title = {Mental control and attributions of blame for negligent
wrongdoing.},
Journal = {Journal of experimental psychology. General},
Volume = {152},
Number = {1},
Pages = {120-138},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1037/xge0001262},
Abstract = {Third-personal judgments of blame are typically sensitive to
what an agent knows and desires. However, when people act
negligently, they do not know what they are doing and do not
desire the outcomes of their negligence. How, then, do
people attribute blame for negligent wrongdoing? We propose
that people attribute blame for negligent wrongdoing based
on perceived <i>mental</i> <i>control</i>, or the degree to
which an agent guides their thoughts and attention over
time. To acquire information about others' mental control,
people self-project their own perceived mental control to
anchor third-personal judgments about mental control and
concomitant responsibility for negligent wrongdoing. In four
experiments (<i>N</i> = 841), we tested whether perceptions
of mental control drive third-personal judgments of blame
for negligent wrongdoing. Study 1 showed that the ease with
which people can counterfactually imagine an individual
being non-negligent mediated the relationship between
judgments of control and blame. Studies 2a and 2b indicated
that perceived mental control has a strong effect on
judgments of blame for negligent wrongdoing and that
first-personal judgments of mental control are moderately
correlated with third-personal judgments of blame for
negligent wrongdoing. Finally, we used an autobiographical
memory manipulation in Study 3 to make personal episodes of
forgetfulness salient. Participants for whom past personal
episodes of forgetfulness were made salient judged negligent
wrongdoers less harshly compared with a control group for
whom past episodes of negligence were not salient.
Collectively, these findings suggest that first-personal
judgments of mental control drive third-personal judgments
of blame for negligent wrongdoing and indicate a novel role
for counterfactual thinking in the attribution of
responsibility. (PsycInfo Database Record (c) 2023 APA, all
rights reserved).},
Doi = {10.1037/xge0001262},
Key = {fds365621}
}
@article{fds372917,
Author = {Uddin, LQ and Betzel, RF and Cohen, JR and Damoiseaux, JS and De
Brigard, F and Eickhoff, SB and Fornito, A and Gratton, C and Gordon,
EM and Laird, AR and Larson-Prior, L and McIntosh, AR and Nickerson, LD and Pessoa, L and Pinho, AL and Poldrack, RA and Razi, A and Sadaghiani, S and Shine, JM and Yendiki, A and Yeo, BTT and Spreng,
RN},
Title = {Controversies and progress on standardization of large-scale
brain network nomenclature.},
Journal = {Network neuroscience (Cambridge, Mass.)},
Volume = {7},
Number = {3},
Pages = {864-905},
Publisher = {M I T PRESS},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1162/netn_a_00323},
Abstract = {Progress in scientific disciplines is accompanied by
standardization of terminology. Network neuroscience, at the
level of macroscale organization of the brain, is beginning
to confront the challenges associated with developing a
taxonomy of its fundamental explanatory constructs. The
Workgroup for HArmonized Taxonomy of NETworks (WHATNET) was
formed in 2020 as an Organization for Human Brain Mapping
(OHBM)-endorsed best practices committee to provide
recommendations on points of consensus, identify open
questions, and highlight areas of ongoing debate in the
service of moving the field toward standardized reporting of
network neuroscience results. The committee conducted a
survey to catalog current practices in large-scale brain
network nomenclature. A few well-known network names (e.g.,
default mode network) dominated responses to the survey, and
a number of illuminating points of disagreement emerged. We
summarize survey results and provide initial considerations
and recommendations from the workgroup. This perspective
piece includes a selective review of challenges to this
enterprise, including (1) network scale, resolution, and
hierarchies; (2) interindividual variability of networks;
(3) dynamics and nonstationarity of networks; (4)
consideration of network affiliations of subcortical
structures; and (5) consideration of multimodal information.
We close with minimal reporting guidelines for the cognitive
and network neuroscience communities to adopt.},
Doi = {10.1162/netn_a_00323},
Key = {fds372917}
}
%% Dodge, Kenneth A.
@article{fds374184,
Author = {Buchanan, CM and Glatz, T and Selçuk, Ş and Skinner, AT and Lansford,
JE and Al-Hassan, SM and Bacchini, D and Bornstein, MH and Chang, L and Deater-Deckard, K and Di Giunta and L and Dodge, KA and Gurdal, S and Liu,
Q and Long, Q and Oburu, P and Pastorelli, C and Sorbring, E and Tapanya,
S and Steinberg, L and Tirado, LMU and Yotanyamaneewong, S and Alampay,
LP},
Title = {Developmental Trajectories of Parental Self-Efficacy as
Children Transition to Adolescence in Nine Countries: Latent
Growth Curve Analyses.},
Journal = {Journal of youth and adolescence},
Volume = {53},
Number = {5},
Pages = {1047-1065},
Year = {2024},
Month = {May},
url = {http://dx.doi.org/10.1007/s10964-023-01899-z},
Abstract = {Little is known about the developmental trajectories of
parental self-efficacy as children transition into
adolescence. This study examined parental self-efficacy
among mothers and fathers over 3 1/2 years representing this
transition, and whether the level and developmental
trajectory of parental self-efficacy varied by cultural
group. Data were drawn from three waves of the Parenting
Across Cultures (PAC) project, a large-scale longitudinal,
cross-cultural study, and included 1178 mothers and 1041
fathers of children who averaged 9.72 years of age at T1
(51.2% girls). Parents were from nine countries (12
ethnic/cultural groups), which were categorized into those
with a predominant collectivistic (i.e., China, Kenya,
Philippines, Thailand, Colombia, and Jordan) or
individualistic (i.e., Italy, Sweden, and USA) cultural
orientation based on Hofstede's Individualism Index
(Hofstede Insights, 2021). Latent growth curve analyses
supported the hypothesis that parental self-efficacy would
decline as children transition into adolescence only for
parents from more individualistic countries; parental
self-efficacy increased over the same years among parents
from more collectivistic countries. Secondary exploratory
analyses showed that some demographic characteristics
predicted the level and trajectory of parental self-efficacy
differently for parents in more individualistic and more
collectivistic countries. Results suggest that declines in
parental self-efficacy documented in previous research are
culturally influenced.},
Doi = {10.1007/s10964-023-01899-z},
Key = {fds374184}
}
@article{fds371229,
Author = {Goulter, N and Hur, YS and Jones, DE and Godwin, J and McMahon, RJ and Dodge, KA and Lansford, JE and Lochman, JE and Bates, JE and Pettit, GS and Crowley, DM},
Title = {Kindergarten conduct problems are associated with monetized
outcomes in adolescence and adulthood.},
Journal = {Journal of child psychology and psychiatry, and allied
disciplines},
Volume = {65},
Number = {3},
Pages = {328-339},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1111/jcpp.13837},
Abstract = {<h4>Background</h4>Across several sites in the United
States, we examined whether kindergarten conduct problems
among mostly population-representative samples of children
were associated with increased criminal and related
(criminal + lost offender productivity + victim;
described as criminal + victim hereafter) costs across
adolescence and adulthood, as well as government and medical
services costs in adulthood.<h4>Methods</h4>Participants
(N = 1,339) were from two multisite longitudinal
studies: Fast Track (n = 754) and the Child Development
Project (n = 585). Parents and teachers reported on
kindergarten conduct problems, administrative and national
database records yielded indexes of criminal offending, and
participants self-reported their government and medical
service use. Outcomes were assigned costs, and significant
associations were adjusted for inflation to determine USD
2020 costs.<h4>Results</h4>A 1SD increase in kindergarten
conduct problems was associated with a $21,934 increase in
adolescent criminal + victim costs, a $63,998 increase in
adult criminal + victim costs, a $12,753 increase in
medical services costs, and a $146,279 increase in total
costs. In the male sample, a 1SD increase in kindergarten
conduct problems was associated with a $28,530 increase in
adolescent criminal + victim costs, a $58,872 increase in
adult criminal + victim costs, and a $144,140 increase
in total costs. In the female sample, a 1SD increase in
kindergarten conduct problems was associated with a $15,481
increase in adolescent criminal + victim costs, a
$62,916 increase in adult criminal + victim costs, a
$24,105 increase in medical services costs, and a $144,823
increase in total costs.<h4>Conclusions</h4>This
investigation provides evidence of the long-term costs
associated with early-starting conduct problems, which is
important information that can be used by policymakers to
support research and programs investing in a strong start
for children.},
Doi = {10.1111/jcpp.13837},
Key = {fds371229}
}
@article{fds372754,
Author = {Copeland, WE and Tong, G and Shanahan, L and Rothenberg, WA and Lansford, JE and Godwin, JW and Rybińska, A and Odgers, CL and Dodge,
KA},
Title = {Intergenerational Effects of a Family Cash Transfer on the
Home Environment.},
Journal = {J Am Acad Child Adolesc Psychiatry},
Volume = {63},
Number = {3},
Pages = {336-344},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1016/j.jaac.2023.08.001},
Abstract = {OBJECTIVE: A natural experiment that provided income
supplements to families has been associated with beneficial
outcomes for children that persisted into adulthood. The
children in this study are now adults, and many are parents.
METHOD: The study builds on the longitudinal, representative
Great Smoky Mountains study conducted from 1993 to 2020. At
follow-up in their late 30s, 1,094 of the 1,348 living
participants (81.2%) were assessed. Of these participants
(67.6%), 739 were parents. A tribe in the area implemented a
cash transfer program of approximately $5,000 annually per
person to every tribal member based on the profits received
from operating a casino. Ten aspects of the home environment
of participants were assessed (eg, family chaos, substance
use, and food insecurity) as well as a composite measure
across all home environment indicators. The proposed
analyses were preregistered (https://osf.io/ex638). RESULTS:
Of the 739 parents assessed, 192 (26.0%) were American
Indians. Parents whose families received cash transfers
during childhood did not differ from parents whose families
did not receive cash transfers on any of the home
environment indicators or the composite measure. At the same
time, there was little evidence of elevated risk for
participants in either group in measures of parental mental
health, substance use, and violence. CONCLUSION: A family
cash transfer in childhood that had long-term effects on
individual functioning did not impact the home environment
of participants who became parents. Rather, parents in both
groups were providing home environments generally conducive
to their children's growth and development. STUDY
PREREGISTRATION INFORMATION: Intergenerational Effects of a
Family Cash Transfer on the Home Environment;
https://osf.io/; ex638.},
Doi = {10.1016/j.jaac.2023.08.001},
Key = {fds372754}
}
@article{fds375376,
Author = {Folker, AE and Deater-Deckard, K and Lansford, JE and Di Giunta and L and Dodge, KA and Gurdal, S and Liu, Q and Long, Q and Oburu, P and Pastorelli,
C and Rothenberg, WA and Skinner, AT and Sorbring, E and Steinberg, L and Tapanya, S and Tirado, LMU and Yotanyamaneewong, S and Alampay, LP and Al-Hassan, SM and Bacchini, D and Bornstein, MH and Chang,
L},
Title = {Intraindividual variability in parental acceptance-rejection
predicts externalizing and internalizing symptoms across
childhood/adolescence in nine countries.},
Journal = {Journal of family psychology : JFP : journal of the Division
of Family Psychology of the American Psychological
Association (Division 43)},
Volume = {38},
Number = {2},
Pages = {333-344},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1037/fam0001133},
Abstract = {Parenting that is high in rejection and low in acceptance is
associated with higher levels of internalizing (INT) and
externalizing (EXT) problems in children and adolescents.
These symptoms develop and can increase in severity to
negatively impact adolescents' social, academic, and
emotional functioning. However, there are two major gaps in
the extant literature: (a) nearly all prior research has
focused on between-person differences in
acceptance/rejection at the expense of examining
intraindividual variability (IIV) across time in
acceptance/rejection; and (b) no prior studies examine IIV
in acceptance/rejection in diverse international samples.
The present study utilized six waves of data with 1,199
adolescents' families living in nine countries from the
Parenting Across Cultures study to test the hypotheses that
(1) higher amounts of youth IIV in mother
acceptance/rejection predict higher internalizing and (2)
externalizing symptoms, and (3) that higher youth IIV in
father acceptance/rejection predict higher internalizing,
and (4) externalizing symptoms. Meta-analytic techniques
indicated a significant, positive effect of IIV in
child-reported mother and father acceptance/rejection on
adolescent externalizing symptoms, and a significant
positive effect of IIV in father acceptance/rejection on
internalizing symptoms. The weighted effect for mother
acceptance/rejection on internalizing symptoms was not
statistically significant. Additionally, there was
significant heterogeneity in all meta-analytic estimates.
More variability over time in experiences of parental
acceptance/rejection predicts internalizing and
externalizing symptoms as children transition into
adolescence, and this effect is present across multiple
diverse samples. (PsycInfo Database Record (c) 2024 APA, all
rights reserved).},
Doi = {10.1037/fam0001133},
Key = {fds375376}
}
@article{fds376228,
Author = {Rothenberg, WA and Lansford, JE and Godwin, JW and Dodge, KA and Copeland, WE and Odgers, CL and McMahon, RJ and Rybinska, A and Conduct
Problems Prevention Research Group},
Title = {Intergenerational Effects of the Fast Track Intervention on
Next-Generation Child Outcomes: A Preregistered Randomized
Clinical Trial.},
Journal = {Am J Psychiatry},
Volume = {181},
Number = {3},
Pages = {213-222},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1176/appi.ajp.20220927},
Abstract = {OBJECTIVE: The authors sought to determine whether the Fast
Track mental health intervention delivered to individuals in
childhood decreased mental health problems and the need for
health services among the children of these individuals.
METHODS: The authors examined whether Fast Track assignment
in one generation of children (generation 2; G2) from grades
1 through 10 reduced parent-reported mental health problems
and health services use in these children's children
(generation 3; G3) 18 years later relative to a control
group. The Fast Track intervention blended parent
behavior-management training, child social-cognitive skills
tutoring, home visits, and classroom social-ecology changes
across grades 1-10 to ameliorate emerging conduct problems
among the G2 children. For this study, 1,057 G3 children of
Fast Track participants (N=581 intervention group, N=476
control group) were evaluated. RESULTS: G3 children of G2
parents who were randomized to the Fast Track intervention
group used fewer general inpatient services and fewer
inpatient or outpatient mental health services compared with
G3 children of G2 parents randomized to the control group.
Some of these effects were mediated: randomization to Fast
Track predicted fewer internalizing problems and less use of
corporal punishment among G2 adults at age 25, which
subsequently predicted less general inpatient service use
and outpatient mental health service use among the G3
children by the time the G2 parents were 34 years old. There
were no significant differences between G3 children from
these two groups on the use of other health services or on
mental health measures. CONCLUSIONS: Fast Track was
associated with lower use of general inpatient services and
inpatient and outpatient mental health services
intergenerationally, but effects on parent-reported mental
health of the children were not apparent across generations.
Investing in interventions for the mental health of children
could reduce service use burdens across generations.},
Doi = {10.1176/appi.ajp.20220927},
Key = {fds376228}
}
@article{fds376229,
Author = {Bustos, B and Lopez, M and Dodge, KA and Lansford, JE and Copeland, WE and Odgers, CL and Bruckner, TA},
Title = {Family cash transfers in childhood and birthing persons and
birth outcomes later in life.},
Journal = {SSM Popul Health},
Volume = {25},
Pages = {101623},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1016/j.ssmph.2024.101623},
Abstract = {Much literature in the US documents an intergenerational
transmission of birthing person and perinatal morbidity in
socioeconomically disadvantaged groups. A separate line of
work indicates that family cash transfers may improve life
chances of low-income families well into adulthood. By
exploiting a quasi-random natural experiment of a large
family cash transfer among a southeastern American Indian
(AI) tribe in rural North Carolina, we examine whether a
"perturbation" in socioeconomic status during childhood
improves birthing person/perinatal outcomes when they become
parents themselves. We acquired birth records on 6805 AI and
non-AI infants born from 1995 to 2018. Regression methods to
examine effect modification tested whether the birthing
person's American Indian (AI) status and exposure to the
family cash transfer during their childhood years
corresponds with improvements in birthing person and
perinatal outcomes. Findings show an increase in age at
childbearing (coef: 0.15 years, 95% confidence interval
[CI]: 0.05, 0.25) and a decrease in pre-pregnancy body mass
index (BMI; coef: -0.42, 95% CI: -0.76, -0.09) with
increased duration of cash transfer exposure during
childhood. The odds of large-for-gestational age at
delivery, as well as mean infant birthweight, is also
reduced among AI births whose birthing person had relatively
longer duration of exposure to the cash transfer. We,
however, observe no relation with other birthing
person/perinatal outcomes (e.g., tobacco use during
pregnancy, preterm birth). In this rural AI population, cash
transfers in one generation correspond with improved
birthing person and infant health in the next
generation.},
Doi = {10.1016/j.ssmph.2024.101623},
Key = {fds376229}
}
@article{fds376272,
Author = {Dodge, KA},
Title = {How a defensive mindset develops from early adverse
experiences and guides antisocial outcomes.},
Journal = {Development and psychopathology},
Pages = {1-7},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1017/s0954579424000348},
Abstract = {Dante Cicchetti has had a lasting impact on our
understanding of the development of externalizing
psychopathology through at least two seminal contributions,
including establishment of the field of developmental
psychopathology and assertion of the hypothesis that early
physical abuse and neglect trigger a cascade of maladaptive
outcomes across the life course. These ideas have guided a
program of research on children's deviant social information
processing and defensive mindset as the psychological
mechanisms through which early physical abuse leads to
long-term psychopathology. Longitudinal studies following
children from early life through mid-adulthood show that
physical abuse in the first five years of life leads
children to adopt a defensive mindset that, in turn,
cascades into long-term outcomes of externalizing
psychopathology, incarceration, and dysfunction. Cicchetti's
ideas have also guided the development of preventive
interventions to interrupt this life course.},
Doi = {10.1017/s0954579424000348},
Key = {fds376272}
}
@article{fds364192,
Author = {Lansford, JE and Rothenberg, WA and Yotanyamaneewong, S and Alampay,
LP and Al-Hassan, SM and Bacchini, D and Bornstein, MH and Chang, L and Deater-Deckard, K and Di Giunta and L and Dodge, KA and Gurdal, S and Liu,
Q and Long, Q and Morgenstern, G and Oburu, P and Pastorelli, C and Skinner, AT and Sorbring, E and Tapanya, S and Steinberg, L and Uribe
Tirado, LM},
Title = {Compliance with Health Recommendations and Vaccine Hesitancy
During the COVID Pandemic in Nine Countries.},
Journal = {Prevention science : the official journal of the Society for
Prevention Research},
Volume = {25},
Number = {2},
Pages = {230-244},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1007/s11121-022-01399-9},
Abstract = {Longitudinal data from the Parenting Across Cultures study
of children, mothers, and fathers in 12 cultural groups in
nine countries (China, Colombia, Italy, Jordan, Kenya, the
Philippines, Sweden, Thailand, and the USA; N = 1331
families) were used to understand predictors of compliance
with COVID-19 mitigation strategies and vaccine hesitancy.
Confidence in government responses to the COVID pandemic was
also examined as a potential moderator of links between
pre-COVID risk factors and compliance with COVID mitigation
strategies and vaccine hesitancy. Greater confidence in
government responses to the COVID pandemic was associated
with greater compliance with COVID mitigation strategies and
less vaccine hesitancy across cultures and reporters.
Pre-COVID financial strain and family stress were less
consistent predictors of compliance with COVID mitigation
strategies and vaccine hesitancy than confidence in
government responses to the pandemic. Findings suggest the
importance of bolstering confidence in government responses
to future human ecosystem disruptions, perhaps through
consistent, clear, non-partisan messaging and transparency
in acknowledging limitations and admitting mistakes to
inspire compliance with government and public health
recommendations.},
Doi = {10.1007/s11121-022-01399-9},
Key = {fds364192}
}
@article{fds375832,
Author = {Carr, RC and Jenkins, JM and Watts, TW and Peisner-Feinberg, ES and Dodge, KA},
Title = {Investigating if high-quality kindergarten teachers sustain
the pre-K boost to children's emergent literacy skill
development in North Carolina.},
Journal = {Child development},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1111/cdev.14076},
Abstract = {This study tested the hypothesis that high-quality
kindergarten teachers sustain and amplify the skill
development of children who participated in North Carolina's
NC Pre-K program during the previous year, compared to
matched non-participants (N = 17,330; 42% African
American, 40% Non-Hispanic White, 15% Hispanic; 51% male;
M<sub>age</sub> = 4.5 years at fall of pre-K).
Kindergarten teacher quality was measured using a
"value-added" approach. NC Pre-K participants outperformed
non-participants in the fall of kindergarten (β = .22)
and 11% of this boost remained evident by the spring of
kindergarten. Higher value-added teachers promoted the skill
development of all children (β = .30 in the spring) but
did not differentially benefit the skill development of
former NC Pre-K participants compared to
non-participants.},
Doi = {10.1111/cdev.14076},
Key = {fds375832}
}
@article{fds376107,
Author = {Gorla, L and Rothenberg, WA and Lansford, JE and Bacchini, D and Bornstein, MH and Chang, L and Deater-Deckard, K and Di Giunta and L and Dodge, KA and Gurdal, S and Junla, D and Liu, Q and Long, Q and Oburu, P and Pastorelli, C and Skinner, AT and Sorbring, E and Steinberg, L and Tirado, LMU and Yotanyamaneewong, S and Alampay, LP and Al-Hassan,
SM},
Title = {Adolescents' relationships with parents and romantic
partners in eight countries.},
Journal = {Journal of adolescence},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1002/jad.12306},
Abstract = {<h4>Introduction</h4>Creating romantic relationships
characterized by high-quality, satisfaction, few conflicts,
and reasoning strategies to handle conflicts is an important
developmental task for adolescents connected to the
relational models they receive from their parents. This
study examines how parent-adolescent conflicts, attachment,
positive parenting, and communication are related to
adolescents' romantic relationship quality, satisfaction,
conflicts, and management.<h4>Method</h4>We interviewed 311
adolescents at two time points (females = 52%, ages 15
and 17) in eight countries (China, Colombia, Italy, Kenya,
the Philippines, Sweden, Thailand, and the United States).
Generalized and linear mixed models were run considering the
participants' nesting within countries.<h4>Results</h4>Adolescents
with negative conflicts with their parents reported low
romantic relationship quality and satisfaction and high
conflicts with their romantic partners. Adolescents
experiencing an anxious attachment to their parents reported
low romantic relationship quality, while adolescents with
positive parenting showed high romantic relationship
satisfaction. However, no association between
parent-adolescent relationships and conflict management
skills involving reasoning with the partner was found. No
associations of parent-adolescent communication with
romantic relationship dimensions emerged, nor was there any
effect of the country on romantic relationship quality or
satisfaction.<h4>Conclusion</h4>These results stress the
relevance of parent-adolescent conflicts and attachment as
factors connected to how adolescents experience romantic
relationships.},
Doi = {10.1002/jad.12306},
Key = {fds376107}
}
@article{fds376700,
Author = {Lansford, JE and Rauer, A and Pettit, GS and Godwin, J and Bates, JE and Dodge, KA},
Title = {PATTERNS OF SINGLEHOOD, COHABITATION, AND MARRIAGE IN EARLY
ADULTHOOD IN RELATION TO WELL-BEING IN ESTABLISHED
ADULTHOOD},
Journal = {Research in Human Development},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1080/15427609.2024.2321400},
Abstract = {In a cohort followed from late adolescence until established
adulthood, this study examined how singlehood, cohabitation,
and marriage at different ages are related to well-being at
age 34. Participants (N = 585) from three U.S. sites
reported their marital and residential status at ages 18,
23, 28, and 34, when they also reported on physical,
psychological, and social indicators of well-being. Findings
suggest that being married compared to single earlier in
adulthood is related to several indicators of better age 34
well-being. Cohabiting participants’ well-being was more
similar to the well-being of the single than married
participants on most indicators.},
Doi = {10.1080/15427609.2024.2321400},
Key = {fds376700}
}
@article{fds375374,
Author = {Rothenberg, WA and Skinner, AT and Lansford, JE and Bacchini, D and Bornstein, MH and Chang, L and Deater-Deckard, K and Di Giunta and L and Dodge, KA and Gurdal, S and Junla, D and Liu, Q and Long, Q and Oburu, P and Pastorelli, C and Sorbring, E and Steinberg, L and Tirado, LMU and Yotanyamaneewong, S and Alampay, LP and Al-Hassan,
SM},
Title = {How adolescents' lives were disrupted over the course of the
COVID-19 pandemic: A longitudinal investigation in 12
cultural groups in 9 nations from March 2020 to July
2022.},
Journal = {Development and psychopathology},
Pages = {1-17},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1017/s0954579423001621},
Abstract = {It is unclear how much adolescents' lives were disrupted
throughout the COVID-19 pandemic or what risk factors
predicted such disruption. To answer these questions, 1,080
adolescents in 9 nations were surveyed 5 times from March
2020 to July 2022. Rates of adolescent COVID-19 life
disruption were stable and high. Adolescents who, compared
to their peers, lived in nations with higher national
COVID-19 death rates, lived in nations with less stringent
COVID-19 mitigation strategies, had less confidence in their
government's response to COVID-19, complied at higher rates
with COVID-19 control measures, experienced the death of
someone they knew due to COVID-19, or experienced more
internalizing, externalizing, and smoking problems reported
more life disruption due to COVID-19 during part or all of
the pandemic. Additionally, when, compared to their typical
levels of functioning, adolescents experienced spikes in
national death rates, experienced less stringent COVID-19
mitigation measures, experienced less confidence in
government response to the COVID-19 pandemic, complied at
higher rates with COVID-19 control measures, experienced
more internalizing problems, or smoked more at various
periods during the pandemic, they also experienced more
COVID-19 life disruption. Collectively, these findings
provide new insights that policymakers can use to prevent
the disruption of adolescents' lives in future
pandemics.},
Doi = {10.1017/s0954579423001621},
Key = {fds375374}
}
@article{fds375349,
Author = {Botvin, C and Jenkins, JM and Carr, RC and Dodge, KA and Clements, D and Sarama, J and Watts, TW},
Title = {Can Peers Help Sustain the Positive Effects of an Early
Childhood Mathematics Intervention?},
Journal = {Early childhood research quarterly},
Volume = {67},
Pages = {159-169},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.ecresq.2023.11.001},
Abstract = {Our study assessed whether the peer environment in
kindergarten and first grade affected student learning
following an early mathematics intervention. We leveraged
longitudinal data from a cluster-RCT to examine whether math
achievement in kindergarten (<i>n</i> = 1,218) and first
grade (<i>n</i> = 1,126) was affected by either the share of
high-achieving classmates or the proportion of classroom
peers who received a preschool math curriculum intervention.
Analyses indicated that exposure to treated peers in first
grade, but not kindergarten, was significantly associated
with small gains in end-of-year achievement. Some analyses
also suggested that average peer math achievement was
generally positively related to children's kindergarten and
first-grade achievement across conditions, though these
results were less robust. We did not find consistent
evidence to suggest that the proportion of treated peers
coincided with better teaching practices. Taken together,
these findings suggest that classroom peer effects may play
only a limited role in sustaining early intervention
effects.},
Doi = {10.1016/j.ecresq.2023.11.001},
Key = {fds375349}
}
@article{fds376699,
Author = {Al-Hassan, SM and Duell, N and Lansford, JE and Dodge, KA and Gurdal, S and Liu, Q and Long, Q and Oburu, P and Pastorelli, C and Skinner, AT and Sorbring, E and Steinberg, L and Tapanya, S and Tirado, LMU and Yotanyamaneewong, S and Alampay, LP and Bacchini, D and Bornstein,
MH and Chang, L and Deater-Deckard, K and Di Giunta,
L},
Title = {Parents’ learning support and school attitudes in relation
to adolescent academic identity and school performance in
nine countries},
Journal = {European Journal of Psychology of Education},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1007/s10212-024-00827-4},
Abstract = {An important question for parents and educators alike is how
to promote adolescents’ academic identity and school
performance. This study investigated relations among
parental education, parents’ attitudes toward their
adolescents’ school, parental support for learning at
home, and adolescents’ academic identity and school
performance over time and in different national contexts.
Longitudinal data were collected from adolescents and their
parents in nine countries (China, Colombia, Italy, Jordan,
Kenya, the Philippines, Sweden, Thailand, and the United
States). When adolescents were 16 years old, their mothers
(N = 1083) and fathers (N = 859) provided data. When
adolescents were 17 years old, 1049 adolescents (50% girls)
and their mothers (N = 1001) and fathers (N = 749) provided
data. Multiple-group path analyses indicated that, across
cultures, higher parent education was associated with better
adolescent school performance. Parents’ attitudes toward
their adolescents’ school and parent support for learning
in the home were not associated with adolescents’ school
performance but were associated with academic identity. The
findings suggest somewhat different pathways to school
performance versus academic identity. Implications for
helping parents and educators in different countries promote
adolescents’ academic identity and achievement are
discussed.},
Doi = {10.1007/s10212-024-00827-4},
Key = {fds376699}
}
@article{fds373882,
Author = {Synergy for the Influence of the Month of Birth in ADHD
(SIMBA) study group},
Title = {Association between relative age at school and persistence
of ADHD in prospective studies: an individual participant
data meta-analysis.},
Journal = {Lancet Psychiatry},
Volume = {10},
Number = {12},
Pages = {922-933},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1016/S2215-0366(23)00272-9},
Abstract = {BACKGROUND: The youngest children in a school class are more
likely than the oldest to be diagnosed with ADHD, but this
relative age effect is less frequent in older than in
younger school-grade children. However, no study has
explored the association between relative age and the
persistence of ADHD diagnosis at older ages. We aimed to
quantify the association between relative age and
persistence of ADHD at older ages. METHODS: For this
meta-analysis, we searched MEDLINE, Embase, CINAHL,
PsycINFO, and PubPsych up to April 1, 2022, with terms
related to "cohort" and "ADHD" with no date, publication
type, or language restrictions. We gathered individual
participant data from prospective cohorts that included at
least ten children identified with ADHD before age 10 years.
ADHD was defined by either a clinical diagnosis or symptoms
exceeding clinical cutoffs. Relative age was recorded as the
month of birth in relation to the school-entry cutoff date.
Study authors were invited to share raw data or to apply a
script to analyse data locally and generate anonymised
results. Our outcome was ADHD status at a diagnostic
reassessment, conducted at least 4 years after the initial
assessment and after age 10 years. No information on sex,
gender, or ethnicity was collected. We did a two-stage
random-effects individual participant data meta-analysis to
assess the association of relative age with persistence of
ADHD at follow-up. This study was registered with PROSPERO,
CRD42020212650. FINDINGS: Of 33 119 studies generated by
our search, we identified 130 eligible unique studies and
were able to gather individual participant data from 57
prospective studies following up 6504 children with ADHD.
After exclusion of 16 studies in regions with a flexible
school entry system that did not allow confident linkage of
birthdate to relative age, the primary analysis included 41
studies in 15 countries following up 4708 children for a
period of 4 to 33 years. We found that younger relative age
was not statistically significantly associated with ADHD
persistence at follow-up (odds ratio 1·02, 95% CI
0·99-1·06; p=0·19). We observed statistically significant
heterogeneity in our model (Q=75·82, p=0·0011, I2=45%).
Participant-level sensitivity analyses showed similar
results in cohorts with a robust relative age effect at
baseline and when restricting to cohorts involving children
with a clinical diagnosis of ADHD or with a follow-up
duration of more than 10 years. INTERPRETATION: The
diagnosis of ADHD in younger children in a class is no more
likely to be disconfirmed over time than that of older
children in the class. One interpretation is that the
relative age effect decreases the likelihood of children of
older relative age receiving a diagnosis of ADHD, and
another is that assigning a diagnostic label of ADHD leads
to unexplored carryover effects of the initial diagnosis
that persist over time. Future studies should be conducted
to explore these interpretations further. FUNDING:
None.},
Doi = {10.1016/S2215-0366(23)00272-9},
Key = {fds373882}
}
@article{fds375375,
Author = {Lansford, JE and Kerry, N and Al-Hassan, SM and Bacchini, D and Bornstein, MH and Chang, L and Deater-Deckard, K and Di Giunta and L and Dodge, KA and Gurdal, S and Junla, D and Oburu, P and Pastorelli, C and Rothenberg, WA and Skinner, AT and Sorbring, E and Steinberg, L and Uribe Tirado and LM and Yotanyamaneewong, S and Alampay,
LP},
Title = {Development of Primal World Beliefs},
Journal = {Human Development},
Pages = {1-10},
Publisher = {S. Karger AG},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1159/000534964},
Abstract = {<jats:p>Primal world beliefs (“primals”) capture
individuals’ basic understanding of what sort of world
this is. How do children develop beliefs about the nature of
the world? Is the world a good place? Safe or dangerous?
Enticing or dull? Primals were initially introduced in
social and personality psychology to understand beliefs
about the world as a whole that may influence well-being and
personality. This article introduces the concept of primals
to developmental scientists and reviews preliminary research
examining how primals relate to sociodemographic and
well-being indicators. The article then situates the concept
of primals in some classic developmental theories to
illustrate testable hypotheses these theories suggest
regarding how primals develop. Understanding how individuals
develop basic beliefs about the nature of the world deepens
insights into the human experience, including how malleable
these beliefs might be and how they may be influenced by,
and in turn influence, other domains of development.
</jats:p>},
Doi = {10.1159/000534964},
Key = {fds375375}
}
@article{fds374379,
Author = {Musci, RJ and Kush, JM and Masyn, KE and Esmaeili, MA and Susukida, R and Goulter, N and McMahon, R and Eddy, JM and Ialongo, NS and Tolan, P and Godwin, J and Conduct Problems Prevention Research Group6, and Wilcox, HC},
Title = {Psychosis Symptom Trajectories Across Childhood and
Adolescence in Three Longitudinal Studies: An Integrative
Data Analysis with Mixture Modeling.},
Journal = {Prevention science : the official journal of the Society for
Prevention Research},
Volume = {24},
Number = {8},
Pages = {1636-1647},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1007/s11121-023-01581-7},
Abstract = {Psychotic-like experiences (PLEs) are common throughout
childhood, and the presence of these experiences is a
significant risk factor for poor mental health later in
development. Given the association of PLEs with a broad
number of mental health diagnoses, these experiences serve
as an important malleable target for early preventive
interventions. However, little is known about these
experiences across childhood. While these experiences may be
common, longitudinal measurement in non-clinical settings is
not. Therefore, in order to explore longitudinal
trajectories of PLEs in childhood, we harmonized three
school-based randomized control trials with longitudinal
follow-up to identify heterogeneity in trajectories of these
experiences. In an integrative data analysis (IDA) using
growth mixture modeling, we identified three latent
trajectory classes. One trajectory class was characterized
by persistent PLEs, one was characterized by high initial
probabilities but improving across the analytic period, and
one was characterized by no reports of PLEs. Compared to the
class without PLEs, those in the improving class were more
likely to be male and have higher levels of aggressive and
disruptive behavior at baseline. In addition to the
substantive impact this work has on PLE research, we also
discuss the methodological innovation as it relates to IDA.
This IDA demonstrates the complexity of pooling data across
multiple studies to estimate longitudinal mixture
models.},
Doi = {10.1007/s11121-023-01581-7},
Key = {fds374379}
}
@article{fds362430,
Author = {Goulter, N and Oberth, C and McMahon, RJ and Lansford, JE and Dodge, KA and Crowley, DM and Bates, JE and Pettit, GS},
Title = {Predictive Validity of Adolescent Callous-Unemotional Traits
and Conduct Problems with Respect to Adult Outcomes: High-
and Low-Risk Samples.},
Journal = {Child psychiatry and human development},
Volume = {54},
Number = {5},
Pages = {1321-1335},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1007/s10578-022-01334-7},
Abstract = {Current understanding of the predictive validity of
callous-unemotional (CU) traits is limited by (a) the focus
on externalizing psychopathology and antisocial behaviors,
(b) a lack of long-term prospective longitudinal data, (c)
samples comprised of high-risk or low-risk individuals. We
tested whether adolescent CU traits and conduct problems
were associated with theoretically relevant adult outcomes
12-18 years later. Participants were drawn from two studies:
higher-risk Fast Track (FT; n = 754) and lower-risk
Child Development Project (CDP; n = 585). FT: conduct
problems positively predicted externalizing and
internalizing psychopathology and partner violence, and
negatively predicted health, wellbeing, and education. Three
conduct problems × CU traits interaction effects were also
found. CDP: CU traits positively predicted depression and
negatively predicted health and education; conduct problems
positively predicted externalizing and internalizing
psychopathology and substance use, and negatively predicted
wellbeing. CU traits did not provide incremental predictive
validity for multiple adult outcomes relative to conduct
problems.},
Doi = {10.1007/s10578-022-01334-7},
Key = {fds362430}
}
@article{fds367702,
Author = {Lansford, JE and Goulter, N and Godwin, J and McMahon, RJ and Dodge, KA and Crowley, M and Pettit, GS and Bates, JE and Lochman,
JE},
Title = {Predictors of problematic adult alcohol, cannabis, and other
substance use: A longitudinal study of two
samples.},
Journal = {Development and psychopathology},
Volume = {35},
Number = {4},
Pages = {2028-2043},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1017/s0954579422000670},
Abstract = {This study examined whether a key set of adolescent and
early adulthood risk factors predicts problematic alcohol,
cannabis, and other substance use in established adulthood.
Two independent samples from the Child Development Project
(CDP; <i>n</i> = 585; 48% girls; 81% White, 17% Black, 2%
other race/ethnicity) and Fast Track (FT; <i>n</i> = 463;
45% girls; 52% White, 43% Black, 5% other race/ethnicity)
were recruited in childhood and followed through age 34
(CDP) or 32 (FT). Predictors of substance use were assessed
in adolescence based on adolescent and parent reports and in
early adulthood based on adult self-reports. Adults reported
their own problematic substance use in established
adulthood. In both samples, more risk factors from
adolescence and early adulthood predicted problematic
alcohol use in established adulthood (compared to
problematic cannabis use and other substance use).
Externalizing behaviors and prior substance use in early
adulthood were consistent predictors of problematic alcohol
and cannabis misuse in established adulthood across samples;
other predictors were specific to the sample and type of
substance misuse. Prevention efforts might benefit from
tailoring to address risk factors for specific substances,
but prioritizing prevention of externalizing behaviors holds
promise for preventing both alcohol and cannabis misuse in
established adulthood.},
Doi = {10.1017/s0954579422000670},
Key = {fds367702}
}
@article{fds361176,
Author = {Lansford, JE and Skinner, AT and Godwin, J and Chang, L and Deater-Deckard, K and Di Giunta and L and Dodge, KA and Gurdal, S and Liu,
Q and Long, Q and Oburu, P and Pastorelli, C and Sorbring, E and Steinberg,
L and Tapanya, S and Uribe Tirado and LM and Yotanyamaneewong, S and Alampay, LP and Al-Hassan, SM and Bacchini, D and Bornstein,
MH},
Title = {Pre-pandemic psychological and behavioral predictors of
responses to the COVID-19 pandemic in nine
countries.},
Journal = {Development and psychopathology},
Volume = {35},
Number = {3},
Pages = {1203-1218},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1017/s0954579421001139},
Abstract = {Prior to the COVID-19 pandemic, adolescents (<i>N</i> =
1,330; <i>M</i><sub>ages</sub> = 15 and 16; 50% female),
mothers, and fathers from nine countries (China, Colombia,
Italy, Jordan, Kenya, Philippines, Sweden, Thailand, United
States) reported on adolescents' internalizing and
externalizing problems, adolescents completed a lab-based
task to assess tendency for risk-taking, and adolescents
reported on their well-being. During the pandemic,
participants (<i>M</i><sub>age</sub> = 20) reported on
changes in their internalizing, externalizing, and substance
use compared to before the pandemic. Across countries,
adolescents' internalizing problems pre-pandemic predicted
increased internalizing during the pandemic, and poorer
well-being pre-pandemic predicted increased externalizing
and substance use during the pandemic. Other relations
varied across countries, and some were moderated by
confidence in the government's handling of the pandemic,
gender, and parents' education.},
Doi = {10.1017/s0954579421001139},
Key = {fds361176}
}
@article{fds370389,
Author = {Rothenberg, WA and Bizzego, A and Esposito, G and Lansford, JE and Al-Hassan, SM and Bacchini, D and Bornstein, MH and Chang, L and Deater-Deckard, K and Di Giunta and L and Dodge, KA and Gurdal, S and Liu,
Q and Long, Q and Oburu, P and Pastorelli, C and Skinner, AT and Sorbring,
E and Tapanya, S and Steinberg, L and Tirado, LMU and Yotanyamaneewong,
S and Alampay, LP},
Title = {Predicting Adolescent Mental Health Outcomes Across
Cultures: A Machine Learning Approach.},
Journal = {Journal of youth and adolescence},
Volume = {52},
Number = {8},
Pages = {1595-1619},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1007/s10964-023-01767-w},
Abstract = {Adolescent mental health problems are rising rapidly around
the world. To combat this rise, clinicians and policymakers
need to know which risk factors matter most in predicting
poor adolescent mental health. Theory-driven research has
identified numerous risk factors that predict adolescent
mental health problems but has difficulty distilling and
replicating these findings. Data-driven machine learning
methods can distill risk factors and replicate findings but
have difficulty interpreting findings because these methods
are atheoretical. This study demonstrates how data- and
theory-driven methods can be integrated to identify the most
important preadolescent risk factors in predicting
adolescent mental health. Machine learning models examined
which of 79 variables assessed at age 10 were the most
important predictors of adolescent mental health at ages 13
and 17. These models were examined in a sample of 1176
families with adolescents from nine nations. Machine
learning models accurately classified 78% of adolescents who
were above-median in age 13 internalizing behavior, 77.3%
who were above-median in age 13 externalizing behavior,
73.2% who were above-median in age 17 externalizing
behavior, and 60.6% who were above-median in age 17
internalizing behavior. Age 10 measures of youth
externalizing and internalizing behavior were the most
important predictors of age 13 and 17 externalizing/internalizing
behavior, followed by family context variables, parenting
behaviors, individual child characteristics, and finally
neighborhood and cultural variables. The combination of
theoretical and machine-learning models strengthens both
approaches and accurately predicts which adolescents
demonstrate above average mental health difficulties in
approximately 7 of 10 adolescents 3-7 years after the data
used in machine learning models were collected.},
Doi = {10.1007/s10964-023-01767-w},
Key = {fds370389}
}
@article{fds367705,
Author = {Rothenberg, WA and Lansford, JE and Tirado, LMU and Yotanyamaneewong,
S and Alampay, LP and Al-Hassan, SM and Bacchini, D and Chang, L and Deater-Deckard, K and Di Giunta and L and Dodge, KA and Gurdal, S and Liu,
Q and Long, Q and Oburu, P and Pastorelli, C and Skinner, AT and Sorbring,
E and Tapanya, S and Steinberg, L and Bornstein, MH},
Title = {The Intergenerational Transmission of Maladaptive Parenting
and its Impact on Child Mental Health: Examining
Cross-Cultural Mediating Pathways and Moderating Protective
Factors.},
Journal = {Child psychiatry and human development},
Volume = {54},
Number = {3},
Pages = {870-890},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1007/s10578-021-01311-6},
Abstract = {Using a sample of 1338 families from 12 cultural groups in 9
nations, we examined whether retrospectively remembered
Generation 1 (G1) parent rejecting behaviors were passed to
Generation 2 (G2 parents), whether such intergenerational
transmission led to higher Generation 3 (G3 child)
externalizing and internalizing behavior at age 13, and
whether such intergenerational transmission could be
interrupted by parent participation in parenting programs or
family income increases of > 5%. Utilizing structural
equation modeling, we found that the intergenerational
transmission of parent rejection that is linked with higher
child externalizing and internalizing problems occurs across
cultural contexts. However, the magnitude of transmission is
greater in cultures with higher normative levels of parent
rejection. Parenting program participation broke this
intergenerational cycle in fathers from cultures high in
normative parent rejection. Income increases appear to break
this intergenerational cycle in mothers from most cultures,
regardless of normative levels of parent rejection. These
results tentatively suggest that bolstering protective
factors such as parenting program participation, income
supplementation, and (in cultures high in normative parent
rejection) legislative changes and other population-wide
positive parenting information campaigns aimed at changing
cultural parenting norms may be effective in breaking
intergenerational cycles of maladaptive parenting and
improving child mental health across multiple
generations.},
Doi = {10.1007/s10578-021-01311-6},
Key = {fds367705}
}
@article{fds370018,
Author = {Baziyants, GA and Dodge, KA and Bai, Y and Goodman, WB and O'Donnell, K and Murphy, RA},
Title = {The effects of a universal short-term home visiting program:
Two-year impact on parenting behavior and parent mental
health.},
Journal = {Child Abuse Negl},
Volume = {140},
Pages = {106140},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1016/j.chiabu.2023.106140},
Abstract = {BACKGROUND: At the time of childbirth, families face
heightened levels of unmet need. These needs, if left unmet,
can lead parents to engage in less positive parenting
practices, which in turn, increase the risk of child
maltreatment. Family Connects (FC) is a universal postnatal
nurse home-visiting program designed to prevent child
maltreatment by supporting all families in a community
through one to three visits to improve parent mental health
and parenting behaviors. A randomized controlled trial of FC
demonstrated improving positive parenting and reducing
postpartum depression through age 6 months. OBJECTIVE: To
determine sustained (2-year) impact of random assignment to
FC on parenting behavior and parent mental health and
identify heterogeneity of effects. PARTICIPANTS AND SETTING:
A representative subsample of 496 families that had been
randomized to FC (255 treatment; 241 control) of infants
born between July 1, 2009, and December 31, 2010, in Durham
County, North Carolina. METHODS: Demographic characteristics
were collected through hospital discharge data.
Treatment-blinded interviewers collected maternal reports of
parenting behavior and mental health at infant age two
years. Moderation and subgroup analyses were conducted to
estimate heterogeneity in impact of FC. RESULTS: Mothers
assigned to FC engaged in more self-reported positive
parenting relative to control mothers (B = 0.21;
p < 0.05). Hispanic mothers assigned to FC reported
greater sense of parenting competence (B = 1.28;
p < 0.05). No significant main effect differences were
identified for negative parenting, maternal depression, or
father involvement. CONCLUSIONS: Assignment to FC was
associated with improvements in population-level
self-reported scores of positive parenting 2 years
post-intervention.},
Doi = {10.1016/j.chiabu.2023.106140},
Key = {fds370018}
}
@article{fds370019,
Author = {Kapetanovic, S and Zietz, S and Lansford, JE and Bacchini, D and Bornstein, MH and Chang, L and Deater-Deckard, K and Di Giunta and L and Dodge, KA and Gurdal, S and Oburu, P and Junla, D and Pastorelli, C and Skinner, AT and Sorbring, E and Tapanya, S and Steinberg, L and Tirado,
LMU and Yotanyamaneewong, S and Alampay, LP and Al-Hassan,
SM},
Title = {Parenting, Adolescent Sensation Seeking, and Subsequent
Substance Use: Moderation by Adolescent Temperament.},
Journal = {Journal of youth and adolescence},
Volume = {52},
Number = {6},
Pages = {1235-1254},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1007/s10964-023-01765-y},
Abstract = {Although previous research has identified links between
parenting and adolescent substance use, little is known
about the role of adolescent individual processes, such as
sensation seeking, and temperamental tendencies for such
links. To test tenets from biopsychosocial models of
adolescent risk behavior and differential susceptibility
theory, this study investigated longitudinal associations
among positive and harsh parenting, adolescent sensation
seeking, and substance use and tested whether the indirect
associations were moderated by adolescent temperament,
including activation control, frustration, sadness, and
positive emotions. Longitudinal data reported by adolescents
(n = 892; 49.66% girls) and their mothers from eight
cultural groups when adolescents were ages 12, 13, and 14
were used. A moderated mediation model showed that parenting
was related to adolescent substance use, both directly and
indirectly, through sensation seeking. Indirect associations
were moderated by adolescent temperament. This study
advances understanding of the developmental paths between
the contextual and individual factors critical for
adolescent substance use across a wide range of cultural
contexts.},
Doi = {10.1007/s10964-023-01765-y},
Key = {fds370019}
}
@article{fds371228,
Author = {Watts, TW and Jenkins, JM and Dodge, KA and Carr, RC and Sauval, M and Bai,
Y and Escueta, M and Duer, J and Ladd, H and Muschkin, C and Peisner-Feinberg, E and Ananat, E},
Title = {Understanding Heterogeneity in the Impact of Public
Preschool Programs.},
Journal = {Monographs of the Society for Research in Child
Development},
Volume = {88},
Number = {1},
Pages = {7-182},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1111/mono.12463},
Abstract = {We examine the North Carolina Pre-K (NC Pre-K) program to
test the hypothesis that observed variation in effects
resulting from exposure to the program can be attributed to
interactions with other environmental factors that occur
before, during, or after the pre-k year. We examine student
outcomes in 5th grade and test interaction effects between
NC's level of investment in public pre-k and moderating
factors. Our main sample includes the population of children
born in North Carolina between 1987 and 2005 who later
attended a public school in that state, had valid
achievement data in 5th grade, and could be matched by
administrative record review (n = 1,207,576; 58% White
non-Hispanic, 29% Black non-Hispanic, 7% Hispanic, 6%
multiracial and Other race/ethnicity). Analyses were based
on a natural experiment leveraging variation in county-level
funding for NC Pre-K across NC counties during each of the
years the state scaled up the program. Exposure to NC Pre-K
funding was defined as the per-4-year-old-child state
allocation of funds to a county in a year. Regression models
included child-level and county-level covariates and county
and year fixed effects. Estimates indicate that a child's
exposure to higher NC Pre-K funding was positively
associated with that child's academic achievement 6 years
later. We found no effect on special education placement or
grade retention. NC Pre-K funding effects on achievement
were positive for all subgroups tested, and statistically
significant for most. However, they were larger for children
exposed to more disadvantaged environments either before or
after the pre-k experience, consistent with a compensatory
model where pre-k provides a buffer against the adverse
effects of prior negative environmental experiences and
protection against the effects of future adverse
experiences. In addition, the effect of NC Pre-K funding on
achievement remained positive across most environments,
supporting an additive effects model. In contrast, few
findings supported a dynamic complementarity model.
Instrumental variables analyses incorporating a child's NC
Pre-K enrollment status indicate that program attendance
increased average 5th grade achievement by approximately 20%
of a standard deviation, and impacts were largest for
children who were Hispanic or whose mothers had less than a
high school education. Implications for the future of pre-k
scale-up and developmental theory are discussed.},
Doi = {10.1111/mono.12463},
Key = {fds371228}
}
@article{fds363824,
Author = {Rothenberg, WA and Lansford, JE and Godwin, JW and Dodge, KA and Copeland, WE and Odgers, CL and McMahon, RJ and Goulter, N and Conduct
Problems Prevention Research Group},
Title = {Intergenerational effects of the Fast Track intervention on
the home environment: A randomized control
trial.},
Journal = {J Child Psychol Psychiatry},
Volume = {64},
Number = {5},
Pages = {820-830},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1111/jcpp.13648},
Abstract = {BACKGROUND: Maladaptive family environments harm child
development and are passed across generations. Childhood
interventions may break this intergenerational cycle by
improving the family environments children form as adults.
The present study investigates this hypothesis by examining
follow-up data collected 18 years after the end of the
childhood Fast Track intervention designed to prevent
externalizing problems. METHODS: We examined whether Fast
Track assignment from grades 1 to 10 prevented the emergence
of maladaptive family environments at age 34. A total of 400
(n = 206 in intervention condition, n = 194
controls) Fast Track participants who were parents at age 34
were surveyed about 11 aspects of their current family
environment. The hypotheses and analytic plan were
preregistered at https://osf.io/dz9t5 and the Fast Track
trial was registered at clinicaltrials.gov (NCT01653535).
RESULTS: Multiple group linear regression models revealed
that mothers who participated in the Fast Track intervention
as children had lower depression symptoms, alcohol problems,
drug problems, corporal punishment use, and food insecurity
compared to control group mothers. All effects were modest
in magnitude. However, for these same mothers, the Fast
Track intervention had no effect on cannabis problems,
experiences of romantic partner violence, or maternal use of
physical aggression or warmth with their children.
Additionally, mothers in the Fast Track intervention group
reported higher levels of family chaos than those in the
control group, but this effect may be a byproduct of the
higher number of children per household in the intervention
group. No intervention effects were found for fathers who
participated in the Fast Track intervention as children.
CONCLUSIONS: Childhood assignment to Fast Track has some
beneficial effects for girls, but not boys, on the family
environments these individuals formed as adults 18 years
later.},
Doi = {10.1111/jcpp.13648},
Key = {fds363824}
}
@article{fds368801,
Author = {Rothenberg, WA and Sorbring, E and Lansford, JE and Peña Alampay and L and Al-Hassan, SM and Bacchini, D and Bornstein, MH and Chang, L and Deater-Deckard, K and Giunta, LD and Dodge, KA and Gurdal, S and Liu, Q and Long, Q and Oburu, P and Pastorelli, C and Skinner, AT and Tapanya, S and Steinberg, L and Maria Uribe Tirado and L and Yotanyamaneewong,
S},
Title = {Predicting child aggression: The role of parent and child
endorsement of reactive aggression across 13 cultural groups
in 9 nations.},
Journal = {Aggressive behavior},
Volume = {49},
Number = {3},
Pages = {183-197},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1002/ab.22067},
Abstract = {Parent and child endorsement of reactive aggression both
predict the emergence of child aggression, but they are
rarely studied together and in longitudinal contexts. The
present study does so by examining the unique predictive
effects of parent and child endorsement of reactive
aggression at age 8 on child aggression at age 9 in 1456
children from 13 cultural groups in 9 nations. Multiple
group structural equation models explored whether age 8
child and parent endorsement of reactive aggression
predicted subsequent age 9 child endorsement of reactive
aggression and child aggression, after accounting for prior
child aggression and parent education. Results revealed that
greater parent endorsement of reactive aggression at age 8
predicted greater child endorsement of aggression at age 9,
that greater parent endorsement of reactive aggression at
age 8 uniquely predicted greater aggression at age 9 in
girls, and that greater child endorsement of reactive
aggression at age 8 uniquely predicted greater aggression at
age 9 in boys. All three of these associations emerged
across cultures. Implications of, and explanations for,
study findings are discussed.},
Doi = {10.1002/ab.22067},
Key = {fds368801}
}
@article{fds371490,
Author = {Rybińska, A and Bai, Y and Goodman, WB and Dodge,
KA},
Title = {Birth Spacing and Child Maltreatment: Population-Level
Estimates for North Carolina.},
Journal = {Child maltreatment},
Pages = {10775595231171879},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1177/10775595231171879},
Abstract = {We examine population-level associations between birth
spacing and child maltreatment using birth records and child
welfare records for 1,099,230 second or higher parity
children born in North Carolina between 1997 and 2013.
Building upon previous research, administrative data
linkages were used to address out-of-state migration and
family-level heterogeneity in birth spacing and child
maltreatment risk factors. Findings provide the strongest
evidence to date that very short birth spacing of zero
through 6 months from last birth to the index child's
conception is a prenatal predictor of child maltreatment
(indexed as child welfare involvement) throughout early
childhood. Consequently, information about optimal family
planning during the postpartum period should become a
standard component of universal and targeted child
maltreatment prevention programs. However, challenging
previous empirical evidence, this study reports inconsistent
results for benefits of additional spacing delay beyond
6 months with regard to child maltreatment risk reduction,
especially for children of racial and ethnic minorities.
These findings call for further inquiry about the mechanisms
driving the connections between birth spacing and Child
Protective Services assessments.},
Doi = {10.1177/10775595231171879},
Key = {fds371490}
}
@article{fds371820,
Author = {Guryan, J and Ludwig, J and Bhatt, MP and Cook, PJ and Davis, JMV and Dodge, K and Farkas, G and Fryer, RG and Mayer, S and Pollack, H and Steinberg, L and Stoddard, G},
Title = {Not Too Late: Improving Academic Outcomes among
Adolescents},
Journal = {American Economic Review},
Volume = {113},
Number = {3},
Pages = {738-765},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1257/aer.20210434},
Abstract = {Improving academic outcomes for economically disadvantaged
students has proven challenging, particularly for children
at older ages. We present two large-scale randomized
controlled trials of a high-dosage tutoring program
delivered to secondary school students in Chicago. One
innovation is to use paraprofessional tutors to hold down
cost, thereby increasing scalability. Participating in math
tutoring increases math test scores by 0.18 to 0.40 standard
deviations and increases math and nonmath course grades.
These effects persist into future years. The data are
consistent with increased personalization of instruction as
a mechanism. The benefit- cost ratio is comparable to many
successful early childhood programs.(JEL H75, I21, I24, I26,
I32, J13, J15).},
Doi = {10.1257/aer.20210434},
Key = {fds371820}
}
@article{fds367845,
Author = {Lansford, JE and Godwin, J and Copeland, WE and Dodge, KA and Odgers,
CL and Rothenberg, WA and Rybińska, A and Conduct Problems
Prevention Research Group},
Title = {Fast Track intervention effects on family
formation.},
Journal = {J Fam Psychol},
Volume = {37},
Number = {1},
Pages = {54-64},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1037/fam0001039},
Abstract = {The present study examines whether the Fast Track (FT)
intervention, a 10-year randomized controlled trial with
children at risk for conduct problems, affects family
formation in adulthood, as indexed by partnerships,
parenthood, and family structure, and whether the
intervention effect differs across participants' gender and
race/ethnicity. Participants included 891 children
(intervention n = 445; control n = 446; 69% male; 51% Black,
47% White) who were recruited in kindergarten and followed
to age 32 or 34 (80% participation of still-living
participants), when they reported on their romantic
partnerships, parenthood, and family structure. Controlling
for numerous covariates that are related to family
formation, intervention participants were more likely than
those in the control group to be married rather than single
and to have a larger number of children; the intervention
and control groups did not differ on cohabitation status,
age at first marriage, whether they had ever been divorced,
their likelihood of being a parent, the age at which they
first became a parent, the spacing of births, family
structure (partnered or not, with or without children), or
in whether they were residentially independent of their
parents and grandparents. Intervention effects were not
moderated by gender, but race/ethnicity moderated the effect
of the intervention on the probability of having any
children and the number of children. These findings suggest
that several elements of family formation may remain
unchanged by an intervention that changes many other
behavioral and psychological trajectories of participants.
(PsycInfo Database Record (c) 2023 APA, all rights
reserved).},
Doi = {10.1037/fam0001039},
Key = {fds367845}
}
@article{fds367583,
Author = {Lansford, JE and Odgers, CL and Bradley, RH and Godwin, J and Copeland,
WE and Rothenberg, WA and Dodge, KA},
Title = {The HOME-21: A revised measure of the home environment for
the 21st century tested in two independent
samples.},
Journal = {Psychol Assess},
Volume = {35},
Number = {1},
Pages = {1-11},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1037/pas0001183},
Abstract = {For decades, the Home Observation for Measurement of the
Environment (HOME) has been the most widely used measure of
children's home environments. This report provides a revised
version of the HOME-Short Form, the HOME-21, reflecting
historical changes in family composition and caregiver
roles, norms about the acceptability of different forms of
discipline, and children's digital environments. Using data
from two samples of parents of children ages 0-17 (Fast
Track [FT], N = 553, age = 33.8, 49.2% female, 48.1% Black,
51.9% White/other; Great Smoky Mountains Study [GSMS], N =
722, age = 37.2, 54.7% female, 67.6% White, 6.6% Black,
25.8% American Indian), we assess the utility of the HOME-21
with descriptive statistics and correlations with a range of
demographic, family context, parenting, and child adjustment
measures. Higher HOME-21 scores were correlated with
obtaining a high school diploma or equivalency diploma (in
GSMS only), having 4 or more years of college, and household
income. HOME-21 was also correlated with having a more
favorable family context indexed by fewer stressful life
events (in FT only), less household food insecurity, lower
household chaos, and more perceived social support. Higher
HOME-21 scores were correlated with better parenting in the
form of parental acceptance, positive parenting, warm
involvement, appropriate and consistent discipline, verbal
discussion, less physical aggression, and greater parental
self-efficacy. Higher HOME-21 scores were correlated with
better child adjustment in terms of fewer emotional and
conduct problems, less hyperactivity, and more prosocial
behavior. The HOME-21 has utility for use in future studies
of children's home environments in the 21st century.
(PsycInfo Database Record (c) 2023 APA, all rights
reserved).},
Doi = {10.1037/pas0001183},
Key = {fds367583}
}
@article{fds374185,
Author = {Remondi, C and Gerbino, M and Zuffianò, A and Pastorelli, C and Thartori, E and Bacchini, D and Di Giunta and L and Lunetti, C and Favini,
A and Lansford, JE and Dodge, KA},
Title = {The developmental trends of parental self-efficacy and
adolescents' rule-breaking behaviors in the Italian context:
A 7-wave latent growth curve study.},
Journal = {PloS one},
Volume = {18},
Number = {11},
Pages = {e0293911},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1371/journal.pone.0293911},
Abstract = {Parental self-efficacy (PSE) captures parents' beliefs in
their ability to perform the parenting role successfully and
to handle pivotal issues of specific developmental periods.
Although previous studies have shown that, across the
transition to adolescence, parents show decreasing levels of
PSE while adolescents exhibit increasing engagement in
rule-breaking (RB) behaviors, there is a paucity of studies
investigating whether and how changes in PSE are related to
late adolescents' RB behaviors across development. The
present study examined the developmental trends of PSE among
Italian mothers and fathers over seven waves (representing
children's transition from late childhood to late
adolescence; approximately from 9 to 18 years old) as well
as the longitudinal associations between PSE and RB
behaviors during late adolescence. Data were drawn from
seven waves of the Parenting Across Cultures (PAC) project,
a large-scale longitudinal, cross-cultural study, and
included 200 Italian children (MAgeAtTime1 = 9.80, SD =
0.65; 50.5% girls) and their parents (200 mothers; 190
fathers). PSE was measured across all seven time-points
(from T1 to T7), while adolescents' RB behaviors were
measured at the first and last assessment (T1 and T7).
Results of univariate latent growth models showed a cubic
trend of mothers' PSE, which revealed a decreasing pattern
characterized initially by a slight decline, followed by a
rebound before continuously decreasing. By contrast,
fathers' PSE followed a linear decrease over time. Finally,
our findings evidenced that only the slope of mothers' PSE
negatively predicted adolescents' RB behaviors at T7,
implying that mothers who maintained higher levels of PSE
over time had children who later engaged in lower RB
behaviors. The study implications are discussed.},
Doi = {10.1371/journal.pone.0293911},
Key = {fds374185}
}
%% Egner, Tobias
@article{fds375277,
Author = {Egner, T and Siqi-Liu, A},
Title = {Insights into control over cognitive flexibility from
studies of task-switching.},
Journal = {Current opinion in behavioral sciences},
Volume = {55},
Pages = {101342},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1016/j.cobeha.2023.101342},
Abstract = {Cognitive flexibility denotes the ability to disengage from
a current task and shift one's focus to a different
activity. An individual's level of flexibility is not fixed;
rather, people adapt their readiness to switch tasks to
changing circumstances. We here review recent studies in the
task-switching literature that have produced new insights
into the contextual factors that drive this adaptation of
flexibility, as well as proposals regarding the underlying
cognitive mechanisms and learning processes. A fast-growing
literature suggests that there are several different means
of learning the need for, and implementing, changes in one's
level of flexibility. These, in turn, have distinct
consequences for the degree to which adjustments in
cognitive flexibility are transferrable to new stimuli and
tasks.},
Doi = {10.1016/j.cobeha.2023.101342},
Key = {fds375277}
}
@article{fds374275,
Author = {Sali, AW and Bejjani, C and Egner, T},
Title = {Learning Cognitive Flexibility: Neural Substrates of
Adapting Switch-Readiness to Time-varying
Demands.},
Journal = {Journal of cognitive neuroscience},
Volume = {36},
Number = {2},
Pages = {377-393},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1162/jocn_a_02091},
Abstract = {An individual's readiness to switch tasks (cognitive
flexibility) varies over time, in part, as the result of
reinforcement learning based on the statistical structure of
the world around them. Consequently, the behavioral cost
associated with task-switching is smaller in contexts where
switching is frequent than where it is rare, but the
underlying brain mechanisms of this adaptation in cognitive
flexibility are not well understood. Here, we manipulated
the likelihood of switches across blocks of trials in a
classic cued task-switching paradigm while participants
underwent fMRI. As anticipated, behavioral switch costs
decreased as the probability of switching increased, and
neural switch costs were observed in lateral and medial
frontoparietal cortex. To study moment-by-moment adjustments
in cognitive flexibility at the neural level, we first
fitted the behavioral RT data with reinforcement learning
algorithms and then used the resulting trial-wise prediction
error estimate as a regressor in a model-based fMRI
analysis. The results revealed that lateral frontal and
parietal cortex activity scaled positively with unsigned
switch prediction error and that there were no brain regions
encoding signed (i.e., switch- or repeat-specific)
prediction error. Taken together, this study documents that
adjustments in cognitive flexibility to time-varying switch
demands are mediated by frontoparietal cortex tracking the
likelihood of forthcoming task switches.},
Doi = {10.1162/jocn_a_02091},
Key = {fds374275}
}
@article{fds374919,
Author = {Şentürk, YD and Ünver, N and Demircan, C and Egner, T and Günseli,
E},
Title = {The reactivation of task rules triggers the reactivation of
task-relevant items.},
Journal = {Cortex; a journal devoted to the study of the nervous system
and behavior},
Volume = {171},
Pages = {465-480},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1016/j.cortex.2023.10.024},
Abstract = {Working memory (WM) describes the temporary storage of
task-relevant items and procedural rules to guide action.
Despite its central importance for goal-directed behavior,
the interplay between WM and long-term memory (LTM) remains
poorly understood. Recent studies have shown that repeated
use of the same task-relevant item in WM results in a
hand-off of the storage of that item to LTM, and switching
to a new item reactivates WM. To further elucidate the rules
governing WM-LTM interactions, we here planned to probe
whether a change in task rules, independent of a switch in
task-relevant items, would also lead to WM reactivation of
maintained items. To this end, we used scalp-recorded
electroencephalogram (EEG) data, specifically the
contralateral delay activity (CDA), to track WM item storage
while manipulating repetitions and changes in task rules and
task-relevant items across trials in a visual WM task. We
tested two rival hypotheses: If changes in task rules result
in a reactivation of the target item representation, then
the CDA should increase when a task change is cued even when
the same target has been repeated across trials. However, if
the reactivation of a task-relevant item only depends on the
mnemonic availability of the item itself instead of the task
it is used for, then only the changes in task-relevant items
should reactivate the representations. Accordingly, the CDA
amplitude should decrease for repeated task-relevant items
independently of a task change. We found a larger CDA on
task-switch compared to task-repeat trials, suggesting that
the reactivation of task rules triggers the reactivation of
task-relevant items in WM. By demonstrating that WM
reactivation of LTM is interdependent for task rules and
task-relevant items, this study informs our understanding of
visual WM and its interplay with LTM. PREREGISTERED STAGE 1
PROTOCOL: https://osf.io/zp9e8 (date of in-principle
acceptance: 19/12/2021).},
Doi = {10.1016/j.cortex.2023.10.024},
Key = {fds374919}
}
@article{fds376165,
Author = {Morales-Torres, R and Egner, T},
Title = {Beyond stimulus-response rules: Task sets incorporate
information about performance difficulty.},
Journal = {Journal of experimental psychology. Learning, memory, and
cognition},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1037/xlm0001337},
Abstract = {The capacity for goal-directed behavior relies on the
generation and implementation of task sets. While task sets
are traditionally defined as mnemonic ensembles linking task
goals to stimulus-response mappings, we here asked the
question whether they may also entail information about task
difficulty: does the level of focus required for performing
a task become incorporated within the task set? We addressed
this question by employing a cued task-switching protocol,
wherein participants engaged in two intermixed tasks with
trial-unique stimuli. Both tasks were equally challenging
during a baseline and a transfer phase, while their
difficulty was manipulated during an intermediate learning
phase by varying the proportion of trials with congruent
versus incongruent response mappings between the two tasks.
Comparing congruency effects between the baseline and
transfer phases, Experiment 1 showed that the task with a
low (high) proportion of congruent trials in the learning
phase displayed reduced (increased) cross-task interference
effects in the transfer phase, indicating that the level of
task focus required in the learning phase had become
associated with each task set. Experiment 2 indicated that
strengthening of task focus level in the task with a low
proportion of congruent trials was the primary driver of
this effect. Experiment 3 ruled out the possibility of
cue-control associations mediating this effect. Taken
together, our results show that task sets can become
associated with the focus level required to successfully
implement them, thus significantly expanding our concept of
the type of information that makes up a task set. (PsycInfo
Database Record (c) 2024 APA, all rights
reserved).},
Doi = {10.1037/xlm0001337},
Key = {fds376165}
}
@article{fds373396,
Author = {Egner, T},
Title = {Principles of cognitive control over task focus and task
switching},
Journal = {Nature Reviews Psychology},
Volume = {2},
Number = {11},
Pages = {702-714},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1038/s44159-023-00234-4},
Abstract = {Adaptive behaviour requires the ability to focus on a task
and protect it from distraction (cognitive stability) and to
rapidly switch tasks when circumstances change (cognitive
flexibility). Burgeoning research literatures have aimed to
understand how people achieve task focus and task switch
readiness. In this Perspective, I integrate these
literatures to derive a cognitive architecture and
functional rules underlying the regulation of cognitive
stability and flexibility. I propose that task focus and
task switch readiness are supported by independent
mechanisms. However, I also suggest that the strategic
regulation of both mechanisms is governed by shared learning
principles: an incremental, online learner that nudges
control up or down based on the recent history of task
demands (a recency heuristic) and episodic reinstatement
when the current context matches a past experience (a
recognition heuristic). Finally, I discuss algorithmic and
neural implementations of these processes, as well as
clinical implications.},
Doi = {10.1038/s44159-023-00234-4},
Key = {fds373396}
}
@article{fds370556,
Author = {Verschooren, S and Egner, T},
Title = {When the mind's eye prevails: The Internal Dominance over
External Attention (IDEA) hypothesis.},
Journal = {Psychonomic bulletin & review},
Volume = {30},
Number = {5},
Pages = {1668-1688},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.3758/s13423-023-02272-8},
Abstract = {Throughout the 20th century, the psychological literature
has considered attention as being primarily directed at the
outside world. More recent theories conceive attention as
also operating on internal information, and mounting
evidence suggests a single, shared attentional focus between
external and internal information. Such sharing implies a
cognitive architecture where attention needs to be
continuously shifted between prioritizing either external or
internal information, but the fundamental principles
underlying this attentional balancing act are currently
unknown. Here, we propose and evaluate one such principle in
the shape of the Internal Dominance over External Attention
(IDEA) hypothesis: Contrary to the traditional view of
attention as being primarily externally oriented, IDEA
asserts that attention is inherently biased toward internal
information. We provide a theoretical account for why such
an internal attention bias may have evolved and examine
findings from a wide range of literatures speaking to the
balancing of external versus internal attention, including
research on working memory, attention switching, visual
search, mind wandering, sustained attention, and meditation.
We argue that major findings in these disparate research
lines can be coherently understood under IDEA. Finally, we
consider tentative neurocognitive mechanisms contributing to
IDEA and examine the practical implications of more
deliberate control over this bias in the context of
psychopathology. It is hoped that this novel hypothesis
motivates cross-talk between the reviewed research lines and
future empirical studies directly examining the mechanisms
that steer attention either inward or outward on a
moment-by-moment basis.},
Doi = {10.3758/s13423-023-02272-8},
Key = {fds370556}
}
@article{fds372781,
Author = {Wang, YC and Adcock, RA and Egner, T},
Title = {Toward an integrative account of internal and external
determinants of event segmentation.},
Journal = {Psychon Bull Rev},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.3758/s13423-023-02375-2},
Abstract = {Our daily experiences unfold continuously, but we remember
them as a series of discrete events through a process called
event segmentation. Prominent theories of event segmentation
suggest that event boundaries in memory are triggered by
significant shifts in the external environment, such as a
change in one's physical surroundings. In this review, we
argue for a fundamental extension of this research field to
also encompass internal state changes as playing a key role
in structuring event memory. Accordingly, we propose an
expanded taxonomy of event boundary-triggering processes,
and review behavioral and neuroscience research on internal
state changes in three core domains: affective states, goal
states, and motivational states. Finally, we evaluate how
well current theoretical frameworks can accommodate the
unique and interactive contributions of internal states to
event memory. We conclude that a theoretical perspective on
event memory that integrates both external environment and
internal state changes allows for a more complete
understanding of how the brain structures experiences, with
important implications for future research in cognitive and
clinical neuroscience.},
Doi = {10.3758/s13423-023-02375-2},
Key = {fds372781}
}
@article{fds370959,
Author = {Wang, YC and Egner, T},
Title = {Target detection does not influence temporal
memory.},
Journal = {Attention, perception & psychophysics},
Volume = {85},
Number = {6},
Pages = {1936-1948},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.3758/s13414-023-02723-3},
Abstract = {Target detection has been found to enhance memory for
concurrently presented stimuli under dual-task conditions.
This "attentional boost effect" is reminiscent of findings
in the event memory literature, where conditions giving rise
to event boundaries have been shown to enhance memory for
boundary items. Target detection commonly requires a working
memory update (e.g., adding to a covert mental target
count), which is also thought to be a key contributor to
creating event boundaries. However, whether target detection
impacts temporal memory in similar ways as event boundaries
remains unknown, because these two parallel literatures have
used different types of memory tests, making direct
comparisons difficult. In a preregistered experiment with
sequential Bayes factor design, we examined whether target
detection influences temporal binding between items by
inserting target and nontarget stimuli during encoding of
trial-unique object images, and then comparing subsequent
temporal order and distance memory for image pairs that span
a target or nontarget. We found that target detection
enhanced recognition memory for target trial images but had
no effect on temporal binding between items. In a follow-up
experiment, we showed that when the encoding task required
updating of task set rather than target count, event
segmentation-related temporal memory effects were observed.
These results document that target detection as such does
not disrupt inter-item associations in memory, and that
attention orienting in the absence of updating task sets
does not create event boundaries. This suggests a key
distinction between declarative and procedural working
memory updates in segmenting events in memory.},
Doi = {10.3758/s13414-023-02723-3},
Key = {fds370959}
}
@article{fds372229,
Author = {Siqi-Liu, A and Egner, T},
Title = {Task sets define boundaries of learned cognitive flexibility
in list-wide proportion switch manipulations.},
Journal = {Journal of experimental psychology. Human perception and
performance},
Volume = {49},
Number = {8},
Pages = {1111-1122},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1037/xhp0001138},
Abstract = {Different contexts in daily life often require varying
levels of cognitive flexibility. Previous research has shown
that people adapt their level of flexibility to match
changing contextual demands for task switching in
cued-switching paradigms that vary the proportion of switch
trials within lists of trials. Specifically, the behavioral
costs of switching as opposed to repeating tasks scale
inversely with the proportion of switches-a finding referred
to as the list-wide proportion switch (LWPS) effect.
Previous research found that flexibility adaptations
transferred across stimuli, but were specifically tied to
task sets, rather than block-wide changes in flexibility
state. In the current study, we conducted additional tests
of the hypothesis that flexibility learning is task specific
in the LWPS paradigm. In Experiments 1 and 2, we used
trial-unique stimuli and unbiased task cues to control for
associative learning tied to stimulus or cue features.
Experiment 3 further tested whether task-specific learning
occurred even for tasks performed on integrated features of
the same stimuli. Across these three experiments, we found
robust task-specific flexibility learning, which transferred
across novel stimuli and unbiased cues and occurred
regardless of stimulus-feature overlap between tasks.
(PsycInfo Database Record (c) 2023 APA, all rights
reserved).},
Doi = {10.1037/xhp0001138},
Key = {fds372229}
}
@article{fds370888,
Author = {Nir-Cohen, G and Egner, T and Kessler, Y},
Title = {The Neural Correlates of Updating and Gating in Procedural
Working Memory.},
Journal = {Journal of cognitive neuroscience},
Volume = {35},
Number = {6},
Pages = {919-940},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1162/jocn_a_01988},
Abstract = {Goal-directed behavior relies on maintaining relevant goals
in working memory (WM) and updating them when required.
Computational modeling, behavioral, and neuroimaging work
has previously identified the processes and brain regions
involved in selecting, updating, and maintaining declarative
information, such as letters and pictures. However, the
neural substrates that underlie the analogous processes that
operate on procedural information, namely, task goals, are
currently unknown. Forty-three participants were therefore
scanned with fMRI while performing a procedural version of
the reference-back paradigm that allowed for the
decomposition of WM updating processes into gate-opening,
gate-closing, task switching, and task cue conflict
components. Significant behavioral costs were observed for
each of these components, with interactions indicating
facilitation between gate-opening and task switching, and a
modulation of cue conflict by gate state. In neural terms,
opening the gate to procedural WM was associated with
activity in medial pFC, posterior parietal cortex (PPC), the
basal ganglia (BG), thalamus, and midbrain, but only when
the task set needed to be updated. Closing the gate to
procedural WM was associated with frontoparietal and BG
activity specifically in conditions where conflicting task
cues had to be ignored. Task switching was associated with
activity in the medial pFC/ACC, PPC, and BG, whereas cue
conflict was associated with PPC and BG activity during gate
closing but was abolished when the gate was already closed.
These results are discussed in relation to declarative WM
and to gating models of WM.},
Doi = {10.1162/jocn_a_01988},
Key = {fds370888}
}
@article{fds368471,
Author = {Wen, T and Egner, T},
Title = {Context-independent scaling of neural responses to task
difficulty in the multiple-demand network.},
Journal = {Cerebral cortex (New York, N.Y. : 1991)},
Volume = {33},
Number = {10},
Pages = {6013-6027},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1093/cercor/bhac479},
Abstract = {The multiple-demand (MD) network is sensitive to many
aspects of cognitive demand, showing increased activation
with more difficult tasks. However, it is currently unknown
whether the MD network is modulated by the context in which
task difficulty is experienced. Using functional magnetic
resonance imaging, we examined MD network responses to low,
medium, and high difficulty arithmetic problems within 2
cued contexts, an easy versus a hard set. The results showed
that MD activity varied reliably with the absolute
difficulty of a problem, independent of the context in which
the problem was presented. Similarly, MD activity during
task execution was independent of the difficulty of the
previous trial. Representational similarity analysis further
supported that representational distances in the MD network
were consistent with a context-independent code. Finally, we
identified several regions outside the MD network that
showed context-dependent coding, including the inferior
parietal lobule, paracentral lobule, posterior insula, and
large areas of the visual cortex. In sum, a cognitive effort
is processed by the MD network in a context-independent
manner. We suggest that this absolute coding of cognitive
demand in the MD network reflects the limited range of task
difficulty that can be supported by the cognitive
apparatus.},
Doi = {10.1093/cercor/bhac479},
Key = {fds368471}
}
@article{fds369143,
Author = {Wen, T and Geddert, RM and Madlon-Kay, S and Egner,
T},
Title = {Transfer of Learned Cognitive Flexibility to Novel Stimuli
and Task Sets.},
Journal = {Psychological science},
Volume = {34},
Number = {4},
Pages = {435-454},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1177/09567976221141854},
Abstract = {Adaptive behavior requires learning about the structure of
one's environment to derive optimal action policies, and
previous studies have documented transfer of such structural
knowledge to bias choices in new environments. Here, we
asked whether people could also acquire and transfer more
abstract knowledge across different task environments,
specifically expectations about cognitive control demands.
Over three experiments, participants (Amazon Mechanical Turk
workers; <i>N</i> = ~80 adults per group) performed a
probabilistic card-sorting task in environments of either a
low or high volatility of task rule changes (requiring low
or high cognitive flexibility, respectively) before
transitioning to a medium-volatility environment. Using
reinforcement-learning modeling, we consistently found that
previous exposure to high task rule volatilities led to
faster adaptation to rule changes in the subsequent transfer
phase. These transfers of expectations about cognitive
flexibility demands were both task independent (Experiment
2) and stimulus independent (Experiment 3), thus
demonstrating the formation and generalization of
environmental structure knowledge to guide cognitive
control.},
Doi = {10.1177/09567976221141854},
Key = {fds369143}
}
%% Erwin, Savannah
@article{fds370373,
Author = {Andrade, FC and Erwin, S and Burnell, K and Jackson, J and Storch, M and Nicholas, J and Zucker, N},
Title = {Intervening on Social Comparisons on Social Media:
Electronic Daily Diary Pilot Study.},
Journal = {Jmir Mental Health},
Volume = {10},
Pages = {e42024},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.2196/42024},
Abstract = {BACKGROUND: Literature has underscored the dark aspects of
social media use, including associations with depressive
symptoms, feelings of social isolation, and diminished
self-esteem. Social comparison, the process of evaluating
oneself relative to another person, is thought to contribute
to these negative experiences such that people with a
stronger tendency to compare themselves with others are
particularly susceptible to the detrimental effects of
social media. Social media as a form of social connection
and communication is nevertheless an inevitable-and arguably
integral-part of life, particularly for young adults.
Therefore, there is a need to investigate strategies that
could alter the manner in which people interact with social
media to minimize its detrimental effects and maximize the
feelings of affiliation and connection. OBJECTIVE: This
pilot study examined the feasibility, acceptability, and
effectiveness of a brief web-based intervention designed to
alter engagement with social media and promote psychological
well-being by encouraging social savoring as an alternative
to social comparison. Social savoring was operationalized as
experiencing joyful emotions related to the happiness of
someone else's experiences (ie, feeling happy for someone
else). METHODS: Following an intensive longitudinal design,
55 college students (mean age 19.29, SD 0.93 years; n=43,
78% women and n=23, 42% White) completed baseline measures
(individual differences, psychological well-being,
connectedness, and social media use) and then 14 days of
daily surveys on their social media activity and well-being.
On day 8, the group that was randomized to receive the
intervention watched a video instructing them on the skill
of social savoring and was asked to practice this skill
during days 8 to 14. RESULTS: Overall, participants reported
positive perceptions of the intervention. Participants who
watched the intervention video reported significantly higher
performance self-esteem (P=.02) at posttest than those in
the control condition, after controlling for baseline
levels. Participants also reported significantly higher
state self-esteem (P=.01) on days in which they engaged in
more social savoring while using social media, and the use
of social savoring increased significantly (P=.01) over
time, suggesting that participants found it helpful.
Participants in both conditions reported significantly lower
levels of social comparison (control: P=.01; intervention:
P=.002) and higher levels of connectedness (control: P<.001;
intervention: P=.001) at posttest than at baseline.
CONCLUSIONS: Initial evidence from this pilot study suggests
that a web-based social savoring intervention may help
minimize the potentially harmful consequences of social
media use, at least in some domains. Future work is needed
to examine the effectiveness and acceptance of this
intervention in different age groups and in clinical samples
that are in part characterized by higher levels of
comparison with others (eg, people with eating
disorders).},
Doi = {10.2196/42024},
Key = {fds370373}
}
%% Fairbank, John A.
@article{fds373514,
Author = {Richardson, SM and Pflieger, JC and Hisle-Gorman, E and Briggs, EC and Fairbank, JA and Stander, VA},
Title = {Family separation from military service and children's
externalizing symptoms: Exploring moderation by non-military
spouse employment, family financial stress, marital quality,
and the parenting alliance},
Journal = {Social Development},
Volume = {33},
Number = {1},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1111/sode.12713},
Abstract = {Military separation is a well-documented vulnerability point
for service members, yet little is known regarding how
children fare across this transition. The current study
examined 909 military-connected children from the Millennium
Cohort Family Study (Wave 1 Mage = 3.88 years, SD =.095)
across a 3-year period to explore whether separation
predicted child externalizing symptoms over and above Wave 1
externalizing levels, by comparing separated versus not
separated military families over time. We also explored if
non-military spouse employment, financial stress, marital
quality, or parenting alliance moderated the relation of
separation with child externalizing. Data were collected via
a parent-reported online questionnaire and administrative
military records. Results showed that separation was
unrelated to externalizing. However, moderation analyses
suggested that for those who separated, non-military
spouses’ employment prior to separation was related to
less externalizing, whereas the parenting alliance was
related to less externalizing only for families who remained
in the military. Recommendations include assistance with
spouse employment prior to military separation and parenting
support throughout military service.},
Doi = {10.1111/sode.12713},
Key = {fds373514}
}
@article{fds372939,
Author = {Elmore Borbon and D and Tant Blackmon and E and Nctsn Unaccompanied
Children Task Force, and Fairbank, JA},
Title = {Trauma-informed care for unaccompanied children: Lessons
learned for practice and policy development.},
Journal = {Psychol Trauma},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1037/tra0001565},
Abstract = {INTRODUCTION: The number of unaccompanied children (UC)
arriving in the United States has increased significantly in
recent years. UC often encounter traumatic events in their
home country, during their migration journey, and upon
resettlement. This article describes a congressionally-funded
initiative to provide trauma-informed mental health services
to UC and children separated from their parents upon arrival
in the United States. It also identifies facilitators and
barriers to working with UC and offers lessons learned to
help inform future practice and policy development aimed at
assisting this vulnerable population. METHOD: Data were
derived from qualitative interviews and a survey
administered to grantees. RESULTS: In total, grantees served
1,195 youth and families across 11 states, including UC,
asylees, and new immigrants during the period of December
2018 through September 2019. Youth and families served spoke
16 languages and originated from diverse nations. Services
provided included direct services to youth and families;
training for providers and community members; partnerships
and collaborations; and resource/product development or
adaptations. DISCUSSION: Lessons learned and recommendations
derived from this initiative can assist others interested in
promoting trauma-informed practice and policies for migrant
children and their families. (PsycInfo Database Record (c)
2023 APA, all rights reserved).},
Doi = {10.1037/tra0001565},
Key = {fds372939}
}
@article{fds372684,
Author = {MacDonald, HZ and Franz, MR and Kaiser, AP and Lee, LO and Lawrence, AE and Fairbank, JA and Vasterling, JJ},
Title = {Associations of Warzone Veteran and Intimate Partner PTSD
Symptoms with Child Depression, Anxiety, Hyperactivity, and
Conduct Problems},
Journal = {Military Behavioral Health},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/21635781.2023.2246894},
Abstract = {Warzone deployment increases risk for posttraumatic stress
disorder symptoms (PTSS), including among service members
who have children. Parental PTSS are associated with child
depression, anxiety, hyperactivity, and conduct problems,
yet few studies of child behavioral health outcomes in
military populations have accounted for PTSS in both warzone
veterans and their partners. Fewer still incorporate
non-clinically-recruited samples of nationally dispersed
warzone veterans and their families. The current research
examines whether children whose parent(s) have higher levels
of PTSS exhibit more behavioral health symptoms. One hundred
and thirty-three Iraq and Afghanistan War veterans and their
cohabitating partners completed clinical interviews and
self-report questionnaires. Higher intimate partner PTSS,
more extensive child exposure to stressful life events, and
being an adolescent were significantly associated with child
depression after adjusting for warzone veteran PTSS,
demographics, and recent warzone veteran absence from the
household. Greater child exposure to stressful life events
was also associated with child conduct problems. Treatment
of PTSD symptoms experienced by warzone veterans’ intimate
partners, and preventative interventions aimed at helping
the children of warzone veterans cope with stress, may
ultimately yield positive benefits for the behavioral health
of children in military families.},
Doi = {10.1080/21635781.2023.2246894},
Key = {fds372684}
}
@article{fds370526,
Author = {Taylor, KA and Mysliwiec, V and Kimbrel, NA and Augustine, AV and VA
Mid-Atlantic MIRECC Registry Workgroup, and Ulmer,
CS},
Title = {Probable trauma associated sleep disorder in post-9/11 US
Veterans.},
Journal = {Sleep Adv},
Volume = {4},
Number = {1},
Pages = {zpad001},
Publisher = {Oxford University Press (OUP)},
Year = {2023},
url = {http://dx.doi.org/10.1093/sleepadvances/zpad001},
Abstract = {STUDY OBJECTIVES: The purpose of this study was to (1)
estimate trauma associated sleep disorder (TASD) prevalence
among post-9/11 era veterans and to describe differences in
service and comorbid mental health clinical characteristics
among individuals with and without probable TASD, and (2)
estimate TASD prevalence and characteristics of reported
traumatic experiences stratified by sex. METHODS: We used
cross-sectional data from the post-deployment mental health
study of post-9/11 veterans, which enrolled and collected
baseline data from 2005 to 2018. We classified veterans as
having probable TASD using self-reported measures: traumatic
experiences from the traumatic life events questionnaire
(TLEQ) and items from the Pittsburgh sleep quality index
with Addendum for posttraumatic stress disorder (PTSD)
mapped to TASD diagnostic criteria and ascertained mental
health diagnoses (PTSD, major depressive disorder [MDD]) via
Structured Clinical Interview for DSM-IV. We calculated
effect sizes as prevalence ratios (PR) for categorical
variables and Hedges' g for continuous variables. RESULTS:
Our final sample included 3618 veterans (22.7% female). TASD
prevalence was 12.1% (95% CI: 11.1% to 13.2%) and
sex-stratified prevalence was similar for female and male
veterans. Veterans with TASD had a much higher comorbid
prevalence of PTSD (PR: 3.72, 95% CI: 3.41 to 4.06) and MDD
(PR: 3.93, 95% CI: 3.48 to 4.43). Combat was the highest
reported most distressing traumatic experience among
veterans with TASD (62.6%). When stratifying by sex, female
veterans with TASD had a wider variety of traumatic
experiences. CONCLUSIONS: Our results support the need for
improved screening and evaluation for TASD in veterans,
which is currently not performed in routine clinical
practice.},
Doi = {10.1093/sleepadvances/zpad001},
Key = {fds370526}
}
%% Finiasz, Zoe
@article{fds375237,
Author = {Finiasz, Z and Gelman, SA and Kushnir, T},
Title = {Testimony and observation of statistical evidence interact
in adults' and children's category-based
induction.},
Journal = {Cognition},
Volume = {244},
Pages = {105707},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1016/j.cognition.2023.105707},
Abstract = {Hearing generic or other kind-relevant claims can influence
the use of information from direct observations in category
learning. In the current study, we ask how both adults and
children integrate their observations with testimony when
learning about the causal property of a novel category.
Participants were randomly assigned to hear one of four
types of testimony: generic, quantified "all", specific, or
only labels. In Study 1, adults (N = 1249) then observed
that some proportion of objects (10%-100%) possessed a
causal property. In Study 2, children (N = 123,
M<sub>age</sub> = 5.06 years, SD = 0.61 years, range
4.01-5.99 years) observed a sample where 30% of the objects
had the causal property. Generic and quantified "all" claims
led both adults and children to generalize the causal
property beyond what was observed. Adults and children
diverged, however, in their overall trust in testimony that
could be verified by observations: adults were more
skeptical of inaccurate quantified claims, whereas children
were more accepting. Additional memory probes suggest that
children's trust in unverified claims may have been due to
misremembering what they saw in favor of what they heard.
The current findings demonstrate that both child and adult
learners integrate information from both sources, offering
insights into the mechanisms by which language frames
first-hand experience.},
Doi = {10.1016/j.cognition.2023.105707},
Key = {fds375237}
}
%% Fitzsimons, Gavan J.
@article{fds374928,
Author = {Abakoumkin, G and Tseliou, E and McCabe, KO and Lemay, EP and Stroebe,
W and Agostini, M and Bélanger, JJ and Gützkow, B and Kreienkamp, J and Kutlaca, M and VanDellen, MR and Abdul Khaiyom and JH and Ahmedi, V and Akkas, H and Almenara, CA and Atta, M and Bagci, SC and Basel, S and Berisha Kida and E and Bernardo, ABI and Buttrick, NR and Chobthamkit,
P and Choi, HS and Cristea, M and Csaba, S and Damnjanovic, K and Danyliuk,
I and Di Santo and D and Douglas, KM and Enea, V and Faller, DG and Fitzsimons, G and Gheorghiu, A and Gómez, Á and Grzymala-Moszczynska, J and Hamaidia, A and Han, Q and Helmy, M and Hudiyana, J and Jeronimus, BF and Jiang, DY and Jovanović, V and Kamenov, Ž and Kende, A and Keng, SL and Kieu, TTT and Koc, Y and Kovyazina, K and Kozytska, I and Krause, J and Kruglanski, AW and Kurapov, A and Lantos, NA and Lesmana, CBJ and Louis, WR and Lueders, A and Malik, NI and Martinez, A and Mehulić, J and Milla, MN and Mohammed, I and Molinario, E and Moyano, M and Muhammad, H and Mula, S and Muluk, H and Myroniuk, S and Najafi, R and Nisa, CF and Nyúl, B and O’Keefe, PA and Olivas Osuna and JJ and Osin, EN and Park, J and Pica, G and Pierro, A and Rees, J and Reitsema, AM and Resta, E and Rullo, M and Ryan, MK and Samekin, A and Santtila, P and Sasin, E and Schumpe, BM and Selim, HA and Stanton, MV and Sultana, S and Sutton, RM and Utsugi, A and van Breen,
JA and Van Lissa and CJ and Van Veen and K and Vázquez, A and Wollast, R and Yeung, VWL and Zand, S and Žeželj, IL and Zheng, B and Zick,
A},
Title = {Conceptual replication and extension of health behavior
theories' predictions in the context of COVID-19: Evidence
across countries and over time},
Journal = {Social and Personality Psychology Compass},
Volume = {18},
Number = {2},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1111/spc3.12909},
Abstract = {Virus mitigation behavior has been and still is a powerful
means to fight the COVID-19 pandemic irrespective of the
availability of pharmaceutical means (e.g., vaccines). We
drew on health behavior theories to predict
health-protective (coping-specific) responses and hope
(coping non-specific response) from health-related
cognitions (vulnerability, severity, self-assessed
knowledge, efficacy). In an extension of this model, we
proposed orientation to internal (problem-focused coping)
and external (country capability) coping resources as
antecedents of health protection and hope; health-related
cognitions were assumed as mediators of this link. We tested
these predictions in a large multi-national multi-wave study
with a cross-sectional panel at T1 (Baseline, March-April
2020; N = 57,631 in 113 countries) and a panel subsample
at two later time points, T2 (November 2020; N = 3097) and
T3 (April 2021; N = 2628). Multilevel models showed that
health-related cognitions predicted health-protective
responses and hope. Problem-focused coping was mainly linked
to health-protective behaviors (T1-T3), whereas country
capability was mainly linked to hope (T1-T3). These
relationships were partially mediated by health-related
cognitions. We conceptually replicated predictions of health
behavior theories within a real health threat, further
suggesting how different coping resources are associated
with qualitatively distinct outcomes. Both patterns were
consistent across countries and time.},
Doi = {10.1111/spc3.12909},
Key = {fds374928}
}
@article{fds376115,
Author = {Wu, F and Samper, A and Morales, AC and Fitzsimons,
GJ},
Title = {When do photos on products hurt or help consumption? How
magical thinking shapes consumer reactions to
photo-integrated products},
Journal = {Journal of Consumer Psychology},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1002/jcpy.1415},
Abstract = {Consumers and companies frequently integrate products with
lifelike photographs of people, animals, and other entities.
However, consumer responses to such products are relatively
unknown. Drawing on magical thinking and moral psychology,
we propose that, due to a photograph's lifelike resemblance
to its referent, consumers believe that photo-integrated
products embody the depicted entity's underlying essence. As
such, in cases where consumption compromises the product's
integrity (e.g., food, disposable goods), people are less
likely to consume photo-integrated products because doing so
is perceived as destroying the depicted entity's essence,
which elicits moral discomfort. In contrast, when the
photographic image remains intact through consumption, as is
the case with durable goods (e.g., magnets), people increase
consumption of photo-integrated products relative to
products without photo integration, consistent with their
popularity in the marketplace. We highlight two strategies
to promote more positive outcomes for managers and consumers
alike: (1) choose images of entities whose essence
destruction is perceived as less immoral, and (2) increase
the durability of the product so the depicted entity's
essence is preserved through consumption.},
Doi = {10.1002/jcpy.1415},
Key = {fds376115}
}
@article{fds370294,
Author = {Westgate, EC and Buttrick, NR and Lin, Y and El Helou and G and Agostini,
M and Bélanger, JJ and Gützkow, B and Kreienkamp, J and Abakoumkin, G and Abdul Khaiyom and JH and Ahmedi, V and Akkas, H and Almenara, CA and Atta,
M and Bagci, SC and Basel, S and Berisha Kida and E and Bernardo, ABI and Chobthamkit, P and Choi, H-S and Cristea, M and Csaba, S and Damnjanovic, K and Danyliuk, I and Dash, A and Di Santo and D and Douglas,
KM and Enea, V and Faller, DG and Fitzsimons, G and Gheorghiu, A and Gómez, Á and Hamaidia, A and Han, Q and Helmy, M and Hudiyana, J and Jeronimus, BF and Jiang, D-Y and Jovanović, V and Kamenov, Ž and Kende, A and Keng, S-L and Kieu, TTT and Koc, Y and Kovyazina, K and Kozytska, I and Krause, J and Kruglanski, AW and Kurapov, A and Kutlaca,
M and Lantos, NA and Lemay, EP and Lesmana, CBJ and Louis, WR and Lueders,
A and Maj, M and Malik, NI and Martinez, A and McCabe, KO and Mehulić, J and Milla, MN and Mohammed, I and Molinario, E and Moyano, M and Muhammad,
H and Mula, S and Muluk, H and Myroniuk, S and Najafi, R and Nisa, CF and Nyúl, B and O'Keefe, PA and Olivas Osuna and JJ and Osin, EN and Park, J and Pica, G and Pierro, A and Rees, J and Reitsema, AM and Resta, E and Rullo,
M and Ryan, MK and Samekin, A and Santtila, P and Sasin, E and Schumpe, BM and Selim, HA and Stanton, MV and Stroebe, W and Sutton, RM and Tseliou, E and Utsugi, A and van Breen, JA and Van Lissa and CJ and Van Veen and K and vanDellen, MR and Vázquez, A and Wollast, R and Et
Al},
Title = {Pandemic boredom: Little evidence that lockdown-related
boredom affects risky public health behaviors across 116
countries.},
Journal = {Emotion (Washington, D.C.)},
Volume = {23},
Number = {8},
Pages = {2370-2384},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1037/emo0001118},
Abstract = {Some public officials have expressed concern that policies
mandating collective public health behaviors (e.g.,
national/regional "lockdown") may result in behavioral
fatigue that ultimately renders such policies ineffective.
Boredom, specifically, has been singled out as one potential
risk factor for noncompliance. We examined whether there was
empirical evidence to support this concern during the
COVID-19 pandemic in a large cross-national sample of 63,336
community respondents from 116 countries. Although boredom
was higher in countries with more COVID-19 cases and in
countries that instituted more stringent lockdowns, such
boredom did not predict longitudinal within-person decreases
in social distancing behavior (or vice versa; <i>n</i> =
8,031) in early spring and summer of 2020. Overall, we found
little evidence that changes in boredom predict individual
public health behaviors (handwashing, staying home,
self-quarantining, and avoiding crowds) over time, or that
such behaviors had any reliable longitudinal effects on
boredom itself. In summary, contrary to concerns, we found
little evidence that boredom posed a public health risk
during lockdown and quarantine. (PsycInfo Database Record
(c) 2023 APA, all rights reserved).},
Doi = {10.1037/emo0001118},
Key = {fds370294}
}
@article{fds371674,
Author = {Douglas, KM and Sutton, RM and Van Lissa and CJ and Stroebe, W and Kreienkamp, J and Agostini, M and Bélanger, JJ and Gützkow, B and Abakoumkin, G and Khaiyom, JHA and Ahmedi, V and Akkas, H and Almenara,
CA and Atta, M and Bagci, SC and Basel, S and Berisha Kida and E and Bernardo,
ABI and Buttrick, NR and Chobthamkit, P and Choi, HS and Cristea, M and Csaba, S and Damnjanovic, K and Danyliuk, I and Dash, A and Di Santo and D and Enea, V and Faller, DG and Fitzsimons, G and Gheorghiu, A and Gómez,
Á and Hamaidia, A and Han, Q and Helmy, M and Hudiyana, J and Jeronimus,
BF and Yu Jiang and D and Jovanović, V and Kamenov, Ž and Kende, A and Keng,
SL and Kieu, TTT and Koc, Y and Kovyazina, K and Kozytska, I and Krause, J and Kruglanski, AW and Kurapov, A and Kutlaca, M and Lantos, NA and Lemay,
EP and Lesmana, CBJ and Louis, WR and Lueders, A and Malik, NI and Martinez, A and McCabe, KO and Mehulić, J and Milla, MN and Mohammed,
I and Molinario, E and Moyano, M and Muhammad, H and Mula, S and Muluk, H and Myroniuk, S and Najafi, R and Nisa, CF and Nyúl, B and O'Keefe, PA and Olivas Osuna and JJ and Osin, EN and Park, J and Pica, G and Pierro, A and Rees, J and Reitsema, AM and Resta, E and Rullo, M and Ryan, MK and Samekin, A and Santtila, P and Sasin, E and Schumpe, BM and Selim, HA and Stanton, MV and Sultana, S and Tseliou, E and Utsugi, A and van Breen,
JA and Van Veen and K and vanDellen, MR and Vázquez, A and Wollast, R and Yeung, VWL and Zand, S and Žeželj, IL and Zheng, B and Zick,
A},
Title = {Identifying important individual- and country-level
predictors of conspiracy theorizing: A machine learning
analysis},
Journal = {European Journal of Social Psychology},
Volume = {53},
Number = {6},
Pages = {1191-1203},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1002/ejsp.2968},
Abstract = {Psychological research on the predictors of conspiracy
theorizing—explaining important social and political
events or circumstances as secret plots by malevolent
groups—has flourished in recent years. However, research
has typically examined only a small number of predictors in
one, or a small number of, national contexts. Such
approaches make it difficult to examine the relative
importance of predictors, and risk overlooking some
potentially relevant variables altogether. To overcome this
limitation, the present study used machine learning to
rank-order the importance of 115 individual- and
country-level variables in predicting conspiracy theorizing.
Data were collected from 56,072 respondents across 28
countries during the early weeks of the COVID-19 pandemic.
Echoing previous findings, important predictors at the
individual level included societal discontent, paranoia, and
personal struggle. Contrary to prior research, important
country-level predictors included indicators of political
stability and effective government COVID response, which
suggests that conspiracy theorizing may thrive in relatively
well-functioning democracies.},
Doi = {10.1002/ejsp.2968},
Key = {fds371674}
}
@article{fds370648,
Author = {Dias, RS and Spiller, SA and Fitzsimons, GJ},
Title = {Understanding effect sizes in consumer psychology},
Journal = {Marketing Letters},
Volume = {34},
Number = {3},
Pages = {367-374},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1007/s11002-023-09680-9},
Abstract = {Over the past decade, behavioral scientists have learned
that many findings in the field may not replicate, leading
to calls for change in how behavioral research is conducted.
Krefeld-Schwalb and Scheibehenne (2023) examine changes in
the methodological practices in consumer research between
2008 and 2020. They find that sample sizes have increased
and that effect sizes have decreased. In this article, we
take these findings as a starting point and reflect on how
we can further improve methodological practices in the
field. We argue that in order to build a more replicable,
rigorous field, we must place effect sizes at the center of
scientific reasoning. Specifically, we make four claims
about effect sizes that we hope will help consumer
researchers plan, conduct, and interpret their research: (1)
effect sizes in consumer psychology are small, and that is a
natural consequence of the field’s maturity; (2) effect
sizes need to be contextualized; (3) our samples are still
too small to detect the small effects of modern empirical
consumer research; and (4) larger samples do not inherently
generate smaller effects. It is our hope that the current
article increases the field’s understanding about effect
sizes and motivates researchers to place effect sizes at the
center of their scientific reasoning. By thinking carefully
about effect sizes, we believe we can collectively improve
methodological practices and confidence in the findings of
consumer psychology.},
Doi = {10.1007/s11002-023-09680-9},
Key = {fds370648}
}
@article{fds362118,
Author = {Enea, V and Eisenbeck, N and Carreno, DF and Douglas, KM and Sutton, RM and Agostini, M and Bélanger, JJ and Gützkow, B and Kreienkamp, J and Abakoumkin, G and Abdul Khaiyom and JH and Ahmedi, V and Akkas, H and Almenara, CA and Atta, M and Bagci, SC and Basel, S and Berisha Kida and E and Bernardo, ABI and Buttrick, NR and Chobthamkit, P and Choi, H-S and Cristea, M and Csaba, S and Damnjanovic, K and Danyliuk, I and Dash, A and Di Santo and D and Faller, DG and Fitzsimons, G and Gheorghiu, A and Gómez, Á and Grzymala-Moszczynska, J and Hamaidia, A and Han, Q and Helmy, M and Hudiyana, J and Jeronimus, BF and Jiang, D-Y and Jovanović, V and Kamenov, Ž and Kende, A and Keng, S-L and Kieu, TTT and Koc, Y and Kovyazina, K and Kozytska, I and Krause, J and Kruglanski,
AW and Kurapov, A and Kutlaca, M and Lantos, NA and Lemay, EP and Lesmana,
CBJ and Louis, WR and Lueders, A and Malik, NI and Martinez, A and McCabe,
KO and Mehulić, J and Milla, MN and Mohammed, I and Molinario, E and Moyano, M and Muhammad, H and Mula, S and Muluk, H and Myroniuk, S and Najafi, R and Nisa, CF and Nyúl, B and O'Keefe, PA and Osuna, JJO and Osin, EN and Park, J and Pica, G and Pierro, A and Rees, J and Reitsema,
AM and Resta, E and Rullo, M and Ryan, MK and Samekin, A and Santtila, P and Sasin, E and Schumpe, BM and Selim, HA and Stanton, MV and Sultana, S and Tseliou, E and Utsugi, A and van Breen, JA and Van Lissa and CJ and Van
Veen, K and vanDellen, MR and Vázquez, A and Wollast, R and Yeung,
VW-L and Zand, S and Žeželj, IL and Zheng, B and Zick, A and Zúñiga, C and Leander, NP},
Title = {Intentions to be Vaccinated Against COVID-19: The Role of
Prosociality and Conspiracy Beliefs across 20
Countries.},
Journal = {Health communication},
Volume = {38},
Number = {8},
Pages = {1530-1539},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1080/10410236.2021.2018179},
Abstract = {Understanding the determinants of COVID-19 vaccine uptake is
important to inform policy decisions and plan vaccination
campaigns. The aims of this research were to: (1) explore
the individual- and country-level determinants of intentions
to be vaccinated against SARS-CoV-2, and (2) examine
worldwide variation in vaccination intentions. This
cross-sectional online survey was conducted during the first
wave of the pandemic, involving 6697 respondents across 20
countries. Results showed that 72.9% of participants
reported positive intentions to be vaccinated against
COVID-19, whereas 16.8% were undecided, and 10.3% reported
they would not be vaccinated. At the individual level,
prosociality was a significant positive predictor of
vaccination intentions, whereas generic beliefs in
conspiracy theories and religiosity were negative
predictors. Country-level determinants, including cultural
dimensions of individualism/collectivism and power distance,
were not significant predictors of vaccination intentions.
Altogether, this study identifies individual-level
predictors that are common across multiple countries,
provides further evidence on the importance of combating
conspiracy theories, involving religious institutions in
vaccination campaigns, and stimulating prosocial motives to
encourage vaccine uptake.},
Doi = {10.1080/10410236.2021.2018179},
Key = {fds362118}
}
@article{fds364191,
Author = {Brick, DJ and Wight, KG and Fitzsimons, GJ},
Title = {Secret consumer behaviors in close relationships},
Journal = {Journal of Consumer Psychology},
Volume = {33},
Number = {2},
Pages = {403-411},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1002/jcpy.1315},
Abstract = {Although close relationships are often characterized by
openness and disclosure, in the present research, we propose
that there are times when individuals choose not to tell
close others about their consumer behavior, keeping it a
secret. For example, one partner may eat a candy bar on the
way home from work, hide a package that was delivered to the
house, or hire a cleaning service and not tell the other
partner. We theorize that this type of consumer behavior is
both common and mundane. That is, the consumption itself is
minor—and has likely been done with the partner's
knowledge in the past—but is being intentionally kept from
the partner. We further investigate whether such behavior
has downstream effects on the relationship, despite its
mundaneness. Five studies support our conceptualization of
secret consumer behaviors in close relationships and
illustrate one consequence: guilt from secret consumption
leads to greater relationship investment. This research
explores a common, yet understudied, area of consumer
behavior and highlights areas for future research. Thus, we
contribute to the literature by being the first work to
examine emotional, behavioral, and relational aspects of
secret consumer behavior.},
Doi = {10.1002/jcpy.1315},
Key = {fds364191}
}
@article{fds369098,
Author = {Brick, DJ and Wight, KG and Bettman, JR and Chartrand, TL and Fitzsimons, GJ},
Title = {Celebrate Good Times: How Celebrations Increase Perceived
Social Support},
Journal = {Journal of Public Policy and Marketing},
Volume = {42},
Number = {2},
Pages = {115-132},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1177/07439156221145696},
Abstract = {Despite the ubiquity of celebrations in everyday life,
little is known about how celebrations may contribute to
consumer well-being. In the current work, the authors
propose that celebrations promote perceived social support,
which prior work has conceptualized as the belief that
others will be there for you for future negative life
events. The authors further theorize that celebrations
require three key characteristics that, in combination, are
necessary for increasing perceived social support.
Specifically, celebrations must (1) mark an individual's
separate positive event and (2) involve consumption (3) with
others (i.e., social). They test this theory across eight
studies and demonstrate a process mechanism for this effect:
these characteristics lead to increases in enacted support
and perceived responsiveness, which in turn lead to
increases in more general perceived social support. They
then extend these findings by investigating virtually held
celebrations, the individual's role at the celebration, and
a downstream prosocial outcome. By doing so, this work
highlights the broader benefits of celebrations beyond the
focal individual and the immediate experience. Finally,
specific policy implications and suggestions for enhancing
consumer well-being are provided.},
Doi = {10.1177/07439156221145696},
Key = {fds369098}
}
@article{fds363803,
Author = {Howe, HS and Zhou, L and Dias, RS and Fitzsimons,
GJ},
Title = {Aha over Haha: Brands benefit more from being clever than
from being funny},
Journal = {Journal of Consumer Psychology},
Volume = {33},
Number = {1},
Pages = {107-114},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1002/jcpy.1307},
Abstract = {We examine whether the cleverness of a brand's humor attempt
affects consumers' brand attitudes and engagement. A clever
humor attempt is any humor attempt wherein the consumer
feels she must make mental connections to solve the joke
(e.g., understand a cultural reference, understand the dual
meaning of a pun). Across five studies, we demonstrate that
as the cleverness of a humor attempt increases, consumers
report higher brand attitudes and are more engaged with the
brand. This effect is mediated by perceptions of brand
warmth and competence and moderated by consumers' need for
cognition.},
Doi = {10.1002/jcpy.1307},
Key = {fds363803}
}
@article{fds371304,
Author = {Han, Q and Zheng, B and Cristea, M and Agostini, M and Bélanger, JJ and Gützkow, B and Kreienkamp, J and PsyCorona Collaboration, and Leander, NP},
Title = {Trust in government regarding COVID-19 and its associations
with preventive health behaviour and prosocial behaviour
during the pandemic: a cross-sectional and longitudinal
study.},
Journal = {Psychological medicine},
Volume = {53},
Number = {1},
Pages = {149-159},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1017/s0033291721001306},
Abstract = {<h4>Background</h4>The effective implementation of
government policies and measures for controlling the
coronavirus disease 2019 (COVID-19) pandemic requires
compliance from the public. This study aimed to examine
cross-sectional and longitudinal associations of trust in
government regarding COVID-19 control with the adoption of
recommended health behaviours and prosocial behaviours, and
potential determinants of trust in government during the
pandemic.<h4>Methods</h4>This study analysed data from the
PsyCorona Survey, an international project on COVID-19 that
included 23 733 participants from 23 countries
(representative in age and gender distributions by country)
at baseline survey and 7785 participants who also completed
follow-up surveys. Specification curve analysis was used to
examine concurrent associations between trust in government
and self-reported behaviours. We further used structural
equation model to explore potential determinants of trust in
government. Multilevel linear regressions were used to
examine associations between baseline trust and longitudinal
behavioural changes.<h4>Results</h4>Higher trust in
government regarding COVID-19 control was significantly
associated with higher adoption of health behaviours
(handwashing, avoiding crowded space, self-quarantine) and
prosocial behaviours in specification curve analyses (median
standardised <i>β</i> = 0.173 and 0.229, <i>p</i> < 0.001).
Government perceived as well organised, disseminating clear
messages and knowledge on COVID-19, and perceived fairness
were positively associated with trust in government
(standardised <i>β</i> = 0.358, 0.230, 0.056, and 0.249,
<i>p</i> < 0.01). Higher trust at baseline survey was
significantly associated with lower rate of decline in
health behaviours over time (<i>p</i> for interaction =
0.001).<h4>Conclusions</h4>These results highlighted the
importance of trust in government in the control of
COVID-19.},
Doi = {10.1017/s0033291721001306},
Key = {fds371304}
}
@article{fds372793,
Author = {Wight, KG and Liu, PJ and Zhou, L and Fitzsimons,
GJ},
Title = {Sharing Food Can Backfire: When Healthy Choices for Children
Lead Parents to Make Unhealthy Choices for
Themselves},
Journal = {Journal of Marketing Research},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1177/00222437231184830},
Abstract = {Many consumers are caregivers and, as part of caregiving,
frequently make food choices for their dependents. This
research examines how food choices made for children
influence the healthiness of parents’ subsequent
self-choices. Whereas prior work focuses on choices for the
self (others) as based on self-needs (other-needs), the
authors theorize when and why self-choices involve
consideration of other-needs. Five studies, including a
nursery school field study, test the effect of choosing
healthy food for a child on the healthiness of parents’
self-choices, focusing on the role of anticipating
potentially sharing self-choices with one's child. Potential
sharing increased parents’ likelihood of making an
unhealthy subsequent self-choice if they first made a
healthy choice for their child. This effect was driven by
parents’ present-focused parenting concerns about whether
one's child would eat and enjoy healthy options chosen for
them. This effect was mitigated when parents instead had
future-focused parenting concerns. Additionally, this effect
was mitigated after making an initial choice for the child
that was (1) unhealthy or (2) healthy but relatively liked
by the child. This research contributes to understanding how
choices for others shape choices for the self and offers
important marketing and policy implications.},
Doi = {10.1177/00222437231184830},
Key = {fds372793}
}
%% Fitzsimons, Grainne
@article{fds372427,
Author = {Wingrove, S and Paek, JJW and Ponce de Leon and R and Fitzsimons,
GM},
Title = {Tying the value of goals to social class.},
Journal = {Journal of personality and social psychology},
Volume = {125},
Number = {4},
Pages = {699-719},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1037/pspa0000346},
Abstract = {Although everyone strives toward valued goals, we suggest
that not everyone will be perceived as doing so equally. In
this research, we examine the tendency to use social class
as a cue to understand the importance of others' goals. Six
studies find evidence of a goal-value bias: Observers
perceive goals across a variety of domains as more valuable
to higher class than to lower class individuals (Studies
1-6). These perceptions do not appear to reflect reality
(pilot study), and those who are strongly motivated to
justify inequality show the bias to a greater extent
(Studies 5 and 6), suggesting a motivated pathway. We also
explore implications of the bias, finding that Americans
tend to offer better opportunities to, and prefer to
collaborate with, higher class than lower class others,
revealing discriminatory outcomes that are partially driven
by perceived goal value (Studies 2, 3, 4, 6). Results
suggest that Americans expect higher class individuals to
value achieving goals more than their lower class
counterparts, fueling increased support for those who are
already ahead. (PsycInfo Database Record (c) 2023 APA, all
rights reserved).},
Doi = {10.1037/pspa0000346},
Key = {fds372427}
}
%% Flanagan, Tess
@article{fds372478,
Author = {Flanagan, T and Wong, G and Kushnir, T},
Title = {The minds of machines: Children's beliefs about the
experiences, thoughts, and morals of familiar interactive
technologies.},
Journal = {Developmental psychology},
Volume = {59},
Number = {6},
Pages = {1017-1031},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1037/dev0001524},
Abstract = {Children are developing alongside interactive technologies
that can move, talk, and act like agents, but it is unclear
if children's beliefs about the agency of these household
technologies are similar to their beliefs about advanced,
humanoid robots used in lab research. This study
investigated 4-11-year-old children's (<i>N</i> = 127,
<i>M</i><sub>age</sub> = 7.50, <i>SD</i><sub>age</sub> =
2.27, 53% females, 75% White; from the Northeastern United
States) beliefs about the mental, physical, emotional, and
moral features of two familiar technologies (Amazon Alexa
and Roomba) in comparison to their beliefs about a humanoid
robot (Nao). Children's beliefs about the agency of these
technologies were organized into three distinct
clusters-having experiences, having minds, and deserving
moral treatment. Children endorsed some agent-like features
for each technology type, but the extent to which they did
so declined with age. Furthermore, children's judgment of
the technologies' freedom to "act otherwise" in moral
scenarios changed with age, suggesting a development shift
in children's understanding of technologies' limitations.
Importantly, there were systematic differences between
Alexa, Roomba, and Nao, that correspond to the unique
characteristics of each. Together these findings suggest
that children's intuitive theories of agency are informed by
an increasingly technological world. (PsycInfo Database
Record (c) 2023 APA, all rights reserved).},
Doi = {10.1037/dev0001524},
Key = {fds372478}
}
%% Fowler, Carina
@article{fds368324,
Author = {Fowler, CH and Bagdasarov, A and Camacho, NL and Reuben, A and Gaffrey,
MS},
Title = {Toxicant exposure and the developing brain: A systematic
review of the structural and functional MRI
literature.},
Journal = {Neuroscience and biobehavioral reviews},
Volume = {144},
Pages = {105006},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1016/j.neubiorev.2022.105006},
Abstract = {Youth worldwide are regularly exposed to pollutants and
chemicals (i.e., toxicants) that may interfere with healthy
brain development, and a surge in MRI research has begun to
characterize the neurobiological consequences of these
exposures. Here, a systematic review following PRISMA
guidelines was conducted on developmental MRI studies of
toxicants with known or suspected neurobiological impact.
Associations were reviewed for 9 toxicant classes, including
metals, air pollution, and flame retardants. Of 1264
identified studies, 46 met inclusion criteria. Qualitative
synthesis revealed that most studies: (1) investigated air
pollutants or metals, (2) assessed exposures prenatally, (3)
assessed the brain in late middle childhood, (4) took place
in North America or Western Europe, (5) drew samples from
existing cohort studies, and (6) have been published since
2017. Given substantial heterogeneity in MRI measures,
toxicant measures, and age groups assessed, more research is
needed on all toxicants reviewed here. Future studies should
also include larger samples, employ personal exposure
monitoring, study independent samples in diverse world
regions, and assess toxicant mixtures.},
Doi = {10.1016/j.neubiorev.2022.105006},
Key = {fds368324}
}
%% Fuemmeler, Bernard F.
@article{fds72465,
Title = {Fuemmeler BF, Agurs-Collins T, McClernon FJ, Kollins SH,
Kail ME, Bergen AW, Ashley-Koch AE. Genes implicated in
serotonergic and dopamine functioning interact with gender
to predict BMI categories: Findings from a nationally
representative sample of young adults. Obesity (in
press) },
Key = {fds72465}
}
@article{fds72466,
Title = {McClernon FJ, Fuemmeler BF, Kollins SH, Kail ME, Ashley-Koch
AE. Interactions between genotype and retrospective ADHD
symptoms predict lifetime smoking risk in a sample of young
adults. Nicotine & Tobacco Research (in press)
},
Key = {fds72466}
}
@article{fds202522,
Title = {Fuemmeler, B. F., Yang, C., Costanzo, P., Hoyle, R.H.,
Siegler, I.C., Williams, R.B., Ostbye, T. (in press).
Parenting styles and BMI trajectories from adolescence into
adulthood: A longitudinal study of the Add Health cohort.
Health Psychology},
Key = {fds202522}
}
@article{fds202523,
Title = {Ranby, K.W., Boynton, M.H., Kollins, S. H., McClernon, J.,
Yang, C., & Fuemmeler, B.F. (in press). Understanding the
phenotypic structure of ADHD in a US population-based
sample. Journal of Clinical Child and Adolescent Psychology.
},
Key = {fds202523}
}
@article{fds211227,
Title = {Fuemmeler, B.F., Lovelady, C.A., Zucker, N.L., Ostbye, T.
(in press). Parental obesity moderates relationship between
childhood appetitive traits and weight. Obesity},
Key = {fds211227}
}
@article{fds211230,
Title = {Fuemmeler, B.F., Pendzich, M.K., Clark, K., Rossoff, P.,
Blatt, J., Lovelady , C., Demark-Wahnefried, W. (in press).
Changes in weight, body composition, diet, and physical
activity during the first year of treatment for childhood
acute leukemia and lymphoma. Journal of Pediatric Hematology
and Oncology },
Key = {fds211230}
}
@article{fds215514,
Title = {Fuemmeler, B.F., Lovelady, C.A., Zucker, N.L., Ostbye, T.
(in press). Parental obesity moderates relationship between
childhood eating behaviors and weight. Obesity },
Key = {fds215514}
}
%% Gaffrey, Michael S.
@article{fds376291,
Author = {Bagdasarov, A and Brunet, D and Michel, CM and Gaffrey,
MS},
Title = {Microstate Analysis of Continuous Infant EEG: Tutorial and
Reliability.},
Journal = {Brain topography},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1007/s10548-024-01043-5},
Abstract = {Microstate analysis of resting-state EEG is a unique
data-driven method for identifying patterns of scalp
potential topographies, or microstates, that reflect stable
but transient periods of synchronized neural activity
evolving dynamically over time. During infancy - a critical
period of rapid brain development and plasticity -
microstate analysis offers a unique opportunity for
characterizing the spatial and temporal dynamics of brain
activity. However, whether measurements derived from this
approach (e.g., temporal properties, transition
probabilities, neural sources) show strong psychometric
properties (i.e., reliability) during infancy is unknown and
key information for advancing our understanding of how
microstates are shaped by early life experiences and whether
they relate to individual differences in infant abilities. A
lack of methodological resources for performing microstate
analysis of infant EEG has further hindered adoption of this
cutting-edge approach by infant researchers. As a result, in
the current study, we systematically addressed these
knowledge gaps and report that most microstate-based
measurements of brain organization and functioning except
for transition probabilities were stable with four minutes
of video-watching resting-state data and highly internally
consistent with just one minute. In addition to these
results, we provide a step-by-step tutorial, accompanying
website, and open-access data for performing microstate
analysis using a free, user-friendly software called
Cartool. Taken together, the current study supports the
reliability and feasibility of using EEG microstate analysis
to study infant brain development and increases the
accessibility of this approach for the field of
developmental neuroscience.},
Doi = {10.1007/s10548-024-01043-5},
Key = {fds376291}
}
@article{fds374967,
Author = {Bagdasarov, A and Roberts, K and Brunet, D and Michel, CM and Gaffrey,
MS},
Title = {Exploring the Association Between EEG Microstates During
Resting-State and Error-Related Activity in Young
Children.},
Journal = {Brain topography},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1007/s10548-023-01030-2},
Abstract = {The error-related negativity (ERN) is a negative deflection
in the electroencephalography (EEG) waveform at
frontal-central scalp sites that occurs after error
commission. The relationship between the ERN and broader
patterns of brain activity measured across the entire scalp
that support error processing during early childhood is
unclear. We examined the relationship between the ERN and
EEG microstates - whole-brain patterns of dynamically
evolving scalp potential topographies that reflect periods
of synchronized neural activity - during both a go/no-go
task and resting-state in 90, 4-8-year-old children. The
mean amplitude of the ERN was quantified during the -64 to
108 millisecond (ms) period of time relative to error
commission, which was determined by data-driven microstate
segmentation of error-related activity. We found that
greater magnitude of the ERN associated with greater global
explained variance (GEV; i.e., the percentage of total
variance in the data explained by a given microstate) of an
error-related microstate observed during the same -64 to 108
ms period (i.e., error-related microstate 3), and to greater
anxiety risk as measured by parent-reported behavioral
inhibition. During resting-state, six data-driven
microstates were identified. Both greater magnitude of the
ERN and greater GEV values of error-related microstate 3
associated with greater GEV values of resting-state
microstate 4, which showed a frontal-central scalp
topography. Source localization results revealed overlap
between the underlying neural generators of error-related
microstate 3 and resting-state microstate 4 and canonical
brain networks (e.g., ventral attention) known to support
the higher-order cognitive processes involved in error
processing. Taken together, our results clarify how
individual differences in error-related and intrinsic brain
activity are related and enhance our understanding of
developing brain network function and organization
supporting error processing during early
childhood.},
Doi = {10.1007/s10548-023-01030-2},
Key = {fds374967}
}
%% Gaither, Sarah E.
@article{fds376854,
Author = {Park, LE and Aknin, LB and Gaither, SE and Impett, EA and Whillans,
AV},
Title = {Starting and sustaining fruitful collaborations in
psychology},
Journal = {Social and Personality Psychology Compass},
Volume = {18},
Number = {4},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1111/spc3.12950},
Abstract = {Much of psychological science relies on collaboration—from
generating new theories and study ideas, to collecting and
analyzing data, to writing and sharing results with the
broader community. Learning how to collaborate with others
is an important skill, yet this process is not often
explicitly discussed in academia. Here, five researchers
from diverse backgrounds share their experiences and advice
on starting and sustaining collaborations. In doing so, they
reflect on aspects of both successful (and failed)
collaborations with students, colleagues within and outside
of psychology, and members of industry and organizational
partners beyond academia. Recommendations and challenges of
productive collaborations are discussed, along with examples
of how collaborative teams can contribute to psychological
science, address real-world issues, and make the process of
conducting research more enjoyable and rewarding.},
Doi = {10.1111/spc3.12950},
Key = {fds376854}
}
@article{fds372782,
Author = {Albuja, AF and Muñoz, M and Kinzler, K and Woodward, A and Gaither,
SE},
Title = {Hypodescent or ingroup overexclusion?: Children's and
adults' racial categorization of ambiguous black/white
biracial faces.},
Journal = {Developmental science},
Volume = {27},
Number = {2},
Pages = {e13450},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1111/desc.13450},
Abstract = {Two processes describe racially ambiguous Black/White
Biracial categorization-the one-drop rule, or hypodescent,
whereby racially ambiguous people are categorized as members
of their socially subordinated racial group (i.e.,
Black/White Biracial faces categorized as Black) and the
ingroup overexclusion effect, whereby racially ambiguous
people are categorized as members of a salient outgroup,
regardless of the group's status. Without developmental
research with racially diverse samples, it is unclear when
these categorization patterns emerge. Study 1 included
White, Black, and racially diverse Biracial children (aged
3- to 7-years) and their parents to test how racial group
membership and social context influence face categorization
biases. To provide the clearest test of hypodescent and
ingroup overexclusion, White participants came from majority
White neighborhoods and Black participants from majority
Black neighborhoods (with Biracial participants from more
racially diverse neighborhoods)-two samples with prominent
racial ingroups. Study 2 aimed to replicate the parent
findings with a separate sample of White, Black, Black/White
Biracial, and Asian adults. Results suggest the ingroup
overexclusion effect is present across populations early in
development and persists into adulthood. Additionally,
categorization was meaningfully related to parental context,
pinpointing a pathway that potentially contributes to
ingroup overexclusion. RESEARCH HIGHLIGHTS: White, Black,
and racially diverse Biracial children and adults tended to
categorize racially ambiguous Black/White Biracial faces as
racial outgroup members, even if the outgroup was White.
This contradicts most work arguing Black/White Biracial
racially ambiguous people are more often seen as Black.
Children and parents' categorizations were related, though
children's categorizations were not related to socialization
above and beyond parents' categorizations. Children showed
similar categorization patterns across dichotomous and
continuous measures.},
Doi = {10.1111/desc.13450},
Key = {fds372782}
}
@article{fds374966,
Author = {Straka, BC and Albuja, A and Leer, J and Brauher, K and Gaither,
SE},
Title = {The rich get richer? Children's reasoning about
socioeconomic status predicts inclusion and resource
bias.},
Journal = {Developmental psychology},
Volume = {60},
Number = {3},
Pages = {505-521},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1037/dev0001655},
Abstract = {Children's socioeconomic status (SES) is linked to disparate
access to resources and affects social behaviors such as
inclusion and resource allocations. Yet it is unclear
whether children's essentialized view of SES (i.e.,
believing SES is immutable) or subjective social status
(SSS) influences behavioral biases toward high- versus
low-SES peers. We measured 4- to 9-year-old children's SES
essentialism and SSS to test whether these predict inclusion
and resource allocations to high- versus low-SES peers
(<i>N</i> = 127; from a midsize city in the Southeastern
United States; 49.6% female; parent-reported 54.2% White,
2.8% Black, 8.3% Latine, 5.6% Asian, 1.4% another race,
27.8% multiracial, 43.3% not provided). We also compared
children's SES beliefs to their parent's. Children's SES
essentialism and SSS decreased across the ages tested, and
children reported higher SSS than their parents. Parents'
SES essentialism predicted younger (but not older)
children's SES essentialism. Moreover, SES essentialism
mediated the negative relationship between age and
preference for including high-SES peers, while SSS mediated
the negative relationship between age and preference for
allocating more resources to high-SES peers. This suggests
that beliefs about the nature of SES may influence
sociorelational behavior like including or excluding others,
while perceived social status (SSS) may influence resource
allocations. Furthermore, older children and those with
lower SES essentialism included low- versus high-SES peers
more often while older and lower SSS children distributed
more resources toward low- versus high-SES peers. Thus,
children's SES essentialism and SSS may also influence their
behaviors to either perpetuate or rectify inequality.
(PsycInfo Database Record (c) 2024 APA, all rights
reserved).},
Doi = {10.1037/dev0001655},
Key = {fds374966}
}
@article{fds374322,
Author = {Hantzmon, SV and Davenport, CA and Das Gupta and MN and Adekunle, TA and Gaither, SE and Olsen, MK and Pinheiro, SO and Johnson, KS and Mahoney,
H and Falls, A and Lloyd, L and Pollak, KI},
Title = {Race differences in patient trust and distrust from
audio-recorded cardiology encounters.},
Journal = {Patient Educ Couns},
Volume = {119},
Pages = {108083},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1016/j.pec.2023.108083},
Abstract = {OBJECTIVE: Many have reported racial disparities in
self-reported trust in clinicians but have not directly
assessed expressions of trust and distrust in
physician-patient encounters. We created a codebook to
examine racial differences in patient trust and distrust
through audio-recorded cardiologist-patient interactions.
METHODS: We analyzed data from a randomized controlled trial
of audio-recorded outpatient cardiology encounters (50 White
and 51 Black patients). We created a codebook for trust and
distrust that was applied to recordings between White
cardiologists and White and Black patients. We assessed
differences in trust, distrust, and guardedness while
adjusting for patient age, sex, and first appointment with
the cardiologist. RESULTS: Compared to White patients, Black
patients had significantly lower expressions of trust ([IRR]
[95 % CI]: 0.59 [0.41, 0.84]) and a significantly lower mean
guarded/open score ([β] [95 % CI] -0.38 [-0.71, -0.04]).
There was no statistically significant association between
race and odds of at least one distrustful expression (OR [95
% CI] 1.36 [0.37, 4.94]). CONCLUSION AND PRACTICE
IMPLICATIONS: We found that coders can reliably identify
patient expressions of trust and distrust rather than
relying on problematic self-reported measures. Results
suggest that White clinicians can improve their
communication with Black patients to increase expressions of
trust.},
Doi = {10.1016/j.pec.2023.108083},
Key = {fds374322}
}
@article{fds355828,
Author = {Tsai, A and Straka, B and Gaither, S},
Title = {Mixed-heritage individuals’ encounters with
raciolinguistic ideologies},
Journal = {Journal of Multilingual and Multicultural
Development},
Volume = {45},
Number = {2},
Pages = {507-521},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1080/01434632.2021.1904964},
Abstract = {Mixed-heritage individuals (MHIs) are known to face high
levels of social exclusion. Here, we investigate how
raciolinguistic ideologies related to one’s heritage
language abilities add to these exclusionary experiences.
The results from 293 MHIs reveal frequent experiences of
marginalisation from members of each of their heritage
communities because their racial appearance and language
practices are perceived as deviant and outside imagined
‘monoracial’ norms. Specifically, over half of
respondents described experiences of exclusion for not
speaking their minority heritage languages with the same
accent or manner or fluency associated with ‘monoracial’
native speakers of their heritage languages or dialects.
Another subset described high pressure to speak ‘proper
English’ in White dominant work environments. These
results extend past MHI work by empirically documenting the
‘monoracial-only’, monoglossic, and ‘Standard
English’ ideologies that contribute to the continued
social exclusion of MHIs.},
Doi = {10.1080/01434632.2021.1904964},
Key = {fds355828}
}
@article{fds371657,
Author = {Adekunle, TA and Knowles, JM and Hantzmon, SV and DasGupta, MN and Pollak, KI and Gaither, SE},
Title = {A qualitative analysis of trust and distrust within
patient-clinician interactions.},
Journal = {PEC Innov},
Volume = {3},
Pages = {100187},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1016/j.pecinn.2023.100187},
Abstract = {OBJECTIVES: Trust represents a key quality of strong
clinician-patient relationships.1 Many have attempted to
assess patient-reported trust. However, most trust measures
suffer from ceiling effects, with no variability, making it
not possible to examine predictors of trust and distrust.
Rather than rely on patient reports, we created a codebook
for instances of trust and distrust from actual
patient-clinician encounters. METHODS: Three coders
conducted a qualitative analysis of audio recordings among
patient-cardiologist outpatient encounters. RESULTS: We
identified trust and distrust based on vocal and verbal cues
in the interactions. We found consistent patterns that
indicated patient trust and distrust. CONCLUSION: Overall,
this work empirically validates a new more accurate
measurement of trust for patient-doctor interactions.
INNOVATION: We are the first to use audio recordings to
identify verbal markers of trust and distrust in
patient-clinician interactions. From this work, others can
code trust and distrust in recorded encounters rather than
rely on self-report measures.},
Doi = {10.1016/j.pecinn.2023.100187},
Key = {fds371657}
}
@article{fds368905,
Author = {Stanaland, A and Gaither, S and Gassman-Pines,
A},
Title = {When Is Masculinity "Fragile"? An Expectancy-Discrepancy-Threat
Model of Masculine Identity.},
Journal = {Personality and social psychology review : an official
journal of the Society for Personality and Social
Psychology, Inc},
Volume = {27},
Number = {4},
Pages = {359-377},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1177/10888683221141176},
Abstract = {<h4>Academic abstract</h4>Manhood is a precarious social
status. Under perceived gender identity threat, men are
disproportionately likely to enact certain
stereotype-consistent responses such as aggression to
maintain their gender status. Yet less is known regarding
individual variation in men's threat responsiveness-that is,
the psychological conditions under which one's masculine
identity is more or less "fragile." We propose a novel model
of masculine identity whereby masculine norm expectancy
generates discrepancy within the self to the extent that
rigid norms are internalized as obligational (actual-ought
discrepancy) versus aspirational (actual-ideal discrepancy),
which predict extrinsic versus intrinsic motivations to
reduce these discrepancies, respectively. Under threat,
then, extrinsic motivations predict externalized responses
(e.g., aggression), and intrinsic motivations elicit
internalized responses (e.g., anxiety, shame, self-harm). We
also consider the conditions under which masculinity may be
less fragile-for example, in contexts with less rigid
expectations and among men who reject expectations-as
pathways to mitigate adverse masculinity threat-related
outcomes.<h4>Public abstract</h4>In many cultures, men prove
their manhood by engaging in behaviors that harm themselves
and others (e.g., violence, sexism, homophobia),
particularly people from marginalized groups. Yet less is
known about why some men are more likely than others to
enact these masculinity-proving behaviors. The goal of our
model is to specify certain conditions under which
masculinities become "fragile" and elicit these responses
when under threat. We start by describing the rigid
expectations men experience-for example, that they are
strong and tough. We propose that these expectations cause
men to experience different forms of discrepancy within
themselves that produce corresponding motivations to reduce
these discrepancies. Under threat, motivations driven by
others' expectations elicit outward attempts to restore
masculine status (e.g., aggression), whereas motivations
driven by self-ideals cause internalized responses (e.g.,
shame, self-harm). We conclude by discussing how to reduce
these discrepancies, such as mitigating the rigidity of and
encouraging men's resistance to masculinity
expectations.},
Doi = {10.1177/10888683221141176},
Key = {fds368905}
}
@article{fds372973,
Author = {Halim, MLD and Atwood, S and Osornio, AC and Pauker, K and Dunham, Y and Olson, KR and Gaither, SE},
Title = {Parent and self-socialization of gender intergroup
attitudes, perceptions, and behaviors among ethnically and
geographically diverse young children.},
Journal = {Developmental psychology},
Volume = {59},
Number = {10},
Pages = {1933-1950},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1037/dev0001586},
Abstract = {Previous work has shown the robust nature of gender bias in
both children and adults. However, much less attention has
been paid toward understanding what factors shape these
biases. The current preregistered study used parent surveys
and child interviews to test whether parents' conversations
with their children about and modeling of gender intergroup
relations and/or children's self-guided interests about
gender (self-socialization) contribute to the formation of
gender attitudes, status perceptions, and gender intergroup
behaviors among young 4- to 6-year-old children. Our
participant sample also allowed us to explore variation by
child gender, ethnicity (Asian-, Black-, Latiné-, and
White-American), and U.S. geographical region (Northeast,
Pacific Northwest, West, Southeast, and Hawaii). Data
suggest that children whose parents reported they were
especially active in seeking information about gender tended
to allocate more resources to same-gender versus
other-gender children and expressed less positive
evaluations of other-gender children in comparison to
children who were less active. By contrast, we found that
parents' conversations with their children about gender
intergroup relations and about gender-play stereotypes
showed few connections with children's gender attitudes. In
terms of demographic differences, boys raised in households
with more unequal versus equal division of labor perceived
that men had higher status than women, but few differences
by ethnicity or geographic region emerged. In sum, our study
suggests that both self- and parent socialization processes
are at play in shaping early gender attitudes, status
perceptions, and gender intergroup behavior, although
self-socialization seemed to play a larger role. (PsycInfo
Database Record (c) 2023 APA, all rights
reserved).},
Doi = {10.1037/dev0001586},
Key = {fds372973}
}
@article{fds372452,
Author = {Chen, JM and Meyers, C and Pauker, K and Gaither, SE and Hamilton, DL and Sherman, JW},
Title = {Intergroup Context Moderates the Impact of White Americans'
Identification on Racial Categorization of Ambiguous
Faces.},
Journal = {Personality & social psychology bulletin},
Pages = {1461672231190264},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1177/01461672231190264},
Abstract = {We examined how the number of groups in a categorization
task influences how White Americans categorize ambiguous
faces. We investigated the strength of <i>identity-driven
ingroup overexclusion</i>-wherein highly identified
perceivers overexclude ambiguous members from the
ingroup-proposing that, compared with dichotomous tasks
(with only the ingroup and one outgroup), tasks with more
outgroups attenuate identity-driven ingroup overexclusion (a
dilution effect). Fourteen studies (<i>n</i> = 4,001)
measured White Americans' racial identification and their
categorizations of ambiguous faces and manipulated the
categorization task to have two groups, three groups, or an
unspecified number of groups (open-ended). In all three
conditions, participants overexcluded faces from the White
category on average. There was limited support for the
dilution effect: identity-driven ingroup overexclusion was
absent in the three-group task and only weakly supported in
the open-ended task. The presence of multiple outgroups may
dampen the impact of racial identity on race perceptions
among White Americans.},
Doi = {10.1177/01461672231190264},
Key = {fds372452}
}
@article{fds361951,
Author = {Gaither, SE and Chen, C-M and Neal, S and Chien, SH-L},
Title = {Children's cross-cultural categorizations of racially
ambiguous faces in Taiwan and the U.S.},
Journal = {Cultural diversity & ethnic minority psychology},
Volume = {29},
Number = {3},
Pages = {385-396},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1037/cdp0000513},
Abstract = {<h4>Objectives</h4>Racially ambiguous face categorization
research is growing in prominence, and yet the majority of
this work has focused on White and Western samples and has
primarily used biracial Black/White stimuli. Past findings
suggest that biracial Black/White faces are more often seen
as Black than White, but without testing these perceptions
with other groups, generalizability cannot be
guaranteed.<h4>Methods</h4>We tested 3-7-year-old Asian
children living in Taiwan-an Eastern cultural context
(<i>N</i> = 74)-and Asian children living in the U.S.-a
Western cultural context (<i>N</i> = 65) to explore the role
that cultural group membership may play in biracial
perceptions. Children categorized 12 racially ambiguous
biracial Black/White faces and 12 biracial Asian/White faces
in a dichotomous forced-choice task and completed a racial
constancy measurement.<h4>Results</h4>Regarding biracial
Black/White faces, Taiwanese and Asian American children
both categorized the faces as White significantly more often
compared to chance levels, regardless of racial constancy
beliefs. For biracial Asian/White faces, Taiwanese children
with racial constancy beliefs categorized the faces
significantly more often as White, whereas Taiwanese
children without racial constancy beliefs categorized the
faces significantly more often as Asian. However, Asian
American children did not show a bias in categorizing
biracial Asian/White faces.<h4>Conclusions</h4>Results
suggest that hyperdescent over hypodescent for more commonly
studied biracial Black/White faces generalizes in both
cultural contexts. However, biracial Asian/White stimuli may
be perceived in more fixed-like patterns in predominately
Asian contexts, since only Taiwanese children showed
increased outgroup categorizations once racial constancy
beliefs were endorsed. (PsycInfo Database Record (c) 2023
APA, all rights reserved).},
Doi = {10.1037/cdp0000513},
Key = {fds361951}
}
@article{fds363071,
Author = {Levy, A and Nguyen, C and Slepian, ML and Gaither, S and Pauker, K and Dovidio, JF},
Title = {Categorizing a Face and Facing a Category: The Constructive
Impacts of Ambiguity and Uncertainty in Racial
Categorization.},
Journal = {Personality & social psychology bulletin},
Volume = {49},
Number = {6},
Pages = {910-924},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1177/01461672221084537},
Abstract = {The past generation has seen a dramatic rise in multiracial
populations and a consequent increase in exposure to
individuals who challenge monolithic racial categories. We
examine and compare two potential outcomes of the
multiracial population growth that may impact people's
racial categorization experience: (a) exposure to racially
ambiguous faces that visually challenge the existing
categories, and (b) a category that conceptually challenges
existing categories (including "biracial" as an option in
addition to the monolithic "Black" and "White" categories).
Across four studies (<i>N</i> = 1,810), we found that
multiple exposures to faces that are racially ambiguous
directly lower essentialist views of race. Moreover, we
found that when people consider a category that blurs the
line between racial categories (i.e., "biracial"), they
become less certain in their racial categorization, which is
associated with less race essentialism, as well.
Importantly, we found that these two effects happen
independently from one another and represent two distinct
cognitive processes.},
Doi = {10.1177/01461672221084537},
Key = {fds363071}
}
@article{fds370891,
Author = {Chen, EE and Ma, S and Bala, M and Groves, JM and Gaither,
SE},
Title = {Do we perceive ethnic ingroup members as wealthier?
Examining Hong Kong children's inferences of wealth status
based on resources and ethnic group membership},
Journal = {Cognitive Development},
Volume = {66},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1016/j.cogdev.2023.101334},
Abstract = {The way in which children consider information may depend on
the groups to which they belong and the social status those
groups occupy. In three studies, we examined how children
infer their peers’ wealth status based on the possessions
present and ethnic group membership. We recruited 242 Hong
Kong children (Mage = 5;11, SDage = 1;0) from the ethnic
Chinese majority (Study 1: 115 children) and two ethnic
minorities (Study 2a: 84 South Asian/Southeast Asian
children; Study 2b: 43 White/Biracial children). Overall,
participants were able to distinguish between low- and
high-wealth items, and make correct wealth-based inferences.
Compared to both groups of ethnic minority children, ethnic
majority children tend to judge their ingroup peers as
wealthier even when they possessed fewer resources than
outgroup peers. Thus, children inferred peer wealth status
based on the resources present, but such inference was
impacted by their own ethnic group membership and
socioeconomic status.},
Doi = {10.1016/j.cogdev.2023.101334},
Key = {fds370891}
}
@article{fds367774,
Author = {Meyers, C and Gaither, SE and Remedios, J and Pauker,
K},
Title = {Detecting biracial identity strength: Perceived
phenotypicality is inaccurate},
Journal = {Self and Identity},
Volume = {22},
Number = {4},
Pages = {533-562},
Publisher = {Informa UK Limited},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/15298868.2022.2146742},
Abstract = {Past work on Black and Latinx individuals demonstrates that
observers can accurately predict an individual’s racial
identity strength based on the observers’ perceptions of
the individual’s phenotypic prototypicality (how much
someone looks like a prototypical member of their racial
group). However, the growing Biracial demographic varies
considerably in racial identification, suggesting a
monoracial approach to infer racial identity strength may
not translate to Biracial individuals. In three studies,
Biracial Black/White participants were photographed and
completed a racial identity strength scale. Subsequently, we
had raters judge the Biracial targets’ phenotypic
prototypicality and perceived levels racial identity
strength. Overall, perceivers could not accurately predict
Biracial individuals’ racial identity strength via their
phenotypic prototypicality.},
Doi = {10.1080/15298868.2022.2146742},
Key = {fds367774}
}
@article{fds374920,
Author = {Halim, MLD and Glazier, JJ and Martinez, MA and Stanaland, A and Gaither, SE and Dunham, Y and Pauker, K and Olson,
KR},
Title = {Gender attitudes and gender discrimination among ethnically
and geographically diverse young children},
Journal = {Infant and Child Development},
Publisher = {WILEY},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1002/icd.2482},
Abstract = {Despite increasing advocacy for gender equality, gender
prejudice and discrimination persist. The origins of these
biases develop in early childhood, but it is less clear
whether (1) children's gender attitudes predict
discrimination and (2) gender attitudes and discrimination
vary by ethnicity and US region. We examine these questions
with an ethnically (Asian, Black, Latinx and White) and
geographically (Northeast, Pacific Northwest, West,
Southeast and Hawaii) diverse sample of 4- to 6-year-old
children (N = 605) who completed measures of gender
attitudes and discrimination in a preregistered study.
Children, across groups, demonstrated more positive
attitudes towards their gender ingroup. Children who showed
more pro-ingroup attitudes also showed more pro-ingroup
behavioural discrimination. Girls showed stronger ingroup
favouritism than boys, but ethnic and regional groups
generally did not vary in levels of bias. These findings
contribute to our understanding of how gender intergroup
biases develop and highlight the generalizability of these
processes.},
Doi = {10.1002/icd.2482},
Key = {fds374920}
}
%% Gassman-Pines, Anna
@article{fds368872,
Author = {Stanaland, A and Gaither, S and Gassman-Pines,
A},
Title = {When Is Masculinity "Fragile"? An Expectancy-Discrepancy-Threat
Model of Masculine Identity.},
Journal = {Personality and social psychology review : an official
journal of the Society for Personality and Social
Psychology, Inc},
Volume = {27},
Number = {4},
Pages = {359-377},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1177/10888683221141176},
Abstract = {<h4>Academic abstract</h4>Manhood is a precarious social
status. Under perceived gender identity threat, men are
disproportionately likely to enact certain
stereotype-consistent responses such as aggression to
maintain their gender status. Yet less is known regarding
individual variation in men's threat responsiveness-that is,
the psychological conditions under which one's masculine
identity is more or less "fragile." We propose a novel model
of masculine identity whereby masculine norm expectancy
generates discrepancy within the self to the extent that
rigid norms are internalized as obligational (actual-ought
discrepancy) versus aspirational (actual-ideal discrepancy),
which predict extrinsic versus intrinsic motivations to
reduce these discrepancies, respectively. Under threat,
then, extrinsic motivations predict externalized responses
(e.g., aggression), and intrinsic motivations elicit
internalized responses (e.g., anxiety, shame, self-harm). We
also consider the conditions under which masculinity may be
less fragile-for example, in contexts with less rigid
expectations and among men who reject expectations-as
pathways to mitigate adverse masculinity threat-related
outcomes.<h4>Public abstract</h4>In many cultures, men prove
their manhood by engaging in behaviors that harm themselves
and others (e.g., violence, sexism, homophobia),
particularly people from marginalized groups. Yet less is
known about why some men are more likely than others to
enact these masculinity-proving behaviors. The goal of our
model is to specify certain conditions under which
masculinities become "fragile" and elicit these responses
when under threat. We start by describing the rigid
expectations men experience-for example, that they are
strong and tough. We propose that these expectations cause
men to experience different forms of discrepancy within
themselves that produce corresponding motivations to reduce
these discrepancies. Under threat, motivations driven by
others' expectations elicit outward attempts to restore
masculine status (e.g., aggression), whereas motivations
driven by self-ideals cause internalized responses (e.g.,
shame, self-harm). We conclude by discussing how to reduce
these discrepancies, such as mitigating the rigidity of and
encouraging men's resistance to masculinity
expectations.},
Doi = {10.1177/10888683221141176},
Key = {fds368872}
}
@article{fds370944,
Author = {Ryan, RM and Gassman-Pines, A and Steimle, S and Baker, G and Hines, CT and Johnson, AD},
Title = {The role of public and private food assistance in supporting
families’ food security and meal routines},
Journal = {Children and Youth Services Review},
Volume = {150},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1016/j.childyouth.2023.106994},
Abstract = {“Backpack” food programs administered through public
schools are a potentially powerful additional source of
nutrition for low-income students and their families.
Typically, backpack programs send non-perishable foods home
with children to supplement school meals. Power Packs
Project (PPP) is a unique backpack program, in that it
provides fresh food alongside accompanying recipes, with the
explicit goals of not only reducing food insecurity but also
facilitating home cooking and improving nutrition for the
whole family. Using daily, repeated surveys sent via
text-message to program parents (N = 178), this study is the
first to examine the effect of picking up a Power Pack in a
given week on parent and child food insecurity and meal
routines. Additionally, it explores whether effects differed
for families who also received federal food assistance
through the Supplemental Nutrition Assistance Program
(SNAP). Results indicate that Power Packs is associated with
lower parent and child food insecurity; this relationship is
even stronger among families who did not also receive SNAP.
Power Packs also promotes home cooking, but only among
families who did not receive SNAP. Analyses of program usage
revealed that SNAP recipients were far more likely to pick
up their packs at the end of their SNAP month than they were
just after SNAP benefit distribution, suggesting they use
the program to smooth food consumption in tandem with SNAP.
Implications of these findings for food assistance programs
and policies are discussed.},
Doi = {10.1016/j.childyouth.2023.106994},
Key = {fds370944}
}
@article{fds370352,
Author = {Gassman-Pines, A and Bellows, L and Copeland, WE and Hoyle, RH and Odgers, CL},
Title = {Day-to-day variation in adolescent food insecurity.},
Journal = {Child Youth Serv Rev},
Volume = {149},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1016/j.childyouth.2023.106954},
Abstract = {This study examined differences in both average and
variability in daily adolescent food insecurity, by
adolescents' levels of economic disadvantage and
race/ethnicity. We used data from a 14-day ecological
momentary assessment of 395 adolescents enrolled in public
schools in North Carolina. Each evening, adolescents were
asked questions about that day's food insecurity.
Economically disadvantaged adolescents reported both higher
average food insecurity and more day-to-day variability in
food insecurity than non-economically disadvantaged
adolescents. Controlling for economic disadvantage, Black
adolescents also experienced both higher average food
insecurity and more variability from day to day than White
or Hispanic adolescents. For those receiving Supplemental
Nutrition Assistance Program (SNAP) benefits, daily food
insecurity was higher in the second half of the month after
SNAP transfer than in the beginning of the month. Food
insecurity among adolescents is not static but varies from
day to day. This daily variation is greater for economically
disadvantaged youth.},
Doi = {10.1016/j.childyouth.2023.106954},
Key = {fds370352}
}
%% Gerlus, Nimesha
@article{fds376040,
Author = {Neacsiu, AD and Beynel, L and Gerlus, N and LaBar, KS and Bukhari-Parlakturk, N and Rosenthal, MZ},
Title = {An experimental examination of neurostimulation and
cognitive restructuring as potential components for
Misophonia interventions.},
Journal = {J Affect Disord},
Volume = {350},
Pages = {274-285},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1016/j.jad.2024.01.120},
Abstract = {Misophonia is a disorder of decreased tolerance to certain
aversive, repetitive common sounds, or to stimuli associated
with these sounds. Two matched groups of adults (29
participants with misophonia and 30 clinical controls with
high emotion dysregulation) received inhibitory
neurostimulation (1 Hz) over a personalized medial
prefrontal cortex (mPFC) target functionally connected to
the left insula; excitatory neurostimulation (10 Hz) over a
personalized dorsolateral PFC (dlPFC) target; and sham
stimulation over either target. Stimulations were applied
while participants were either listening or cognitively
downregulating emotions associated with personalized
aversive, misophonic, or neutral sounds. Subjective units of
distress (SUDS) and psychophysiological measurements (e.g.,
skin conductance response [SCR] and level [SCL]) were
collected. Compared to controls, participants with
misophonia reported higher distress (∆SUDS = 1.91-1.93,
ps < 0.001) when listening to and when downregulating
misophonic distress. Both types of neurostimulation reduced
distress significantly more than sham, with excitatory rTMS
providing the most benefit (Cohen's dSUDS = 0.53;
dSCL = 0.14). Excitatory rTMS also enhanced the regulation
of emotions associated with misophonic sounds in both groups
when measured by SUDS (dcontrol = 1.28;
dMisophonia = 0.94), and in the misophonia group alone
when measured with SCL (d = 0.20). Both types of
neurostimulation were well tolerated. Engaging in cognitive
restructuring enhanced with high-frequency neurostimulation
led to the lowest misophonic distress, highlighting the best
path forward for misophonia interventions.},
Doi = {10.1016/j.jad.2024.01.120},
Key = {fds376040}
}
%% Gibson-Davis, Christina M.
@article{fds375348,
Author = {Zang, E and Gibson-Davis, C and Li, H},
Title = {Beyond parental wealth: Grandparental wealth and the
transition to adulthood},
Journal = {Research in Social Stratification and Mobility},
Volume = {89},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1016/j.rssm.2023.100878},
Abstract = {This study considers the multigenerational consequences of
wealth transmission for the transition to young adulthood.
Using a wider set of outcomes than has previously been
considered, and by analyzing parental and grandparental
wealth simultaneously, this work underscores the salience of
multiple generations of wealth as a predictor for young
adult well-being. Data comes from the US Panel Study of
Income Dynamics on a sample of youth followed from
mid-adolescence until the age of 20. Results from linear
regression models indicate that parental wealth was
associated with increases in the probability of college
attendance and steady employment and inversely associated
with the likelihood of nonmarital birth and idleness.
Grandparental wealth predicted non-educational outcomes at
least as well as parental wealth did and explained more
variance in young adults’ outcomes when parental wealth
was lower. The association between parental wealth and
non-educational outcomes suggest that wealth may inform
young adults’ broader life course by predicting outcomes
other than college attendance. Grandparental wealth may
serve a compensatory function for children with low parental
wealth. Results suggest that persistently low wealth across
multiple generations may impede the successful transition to
young adulthood.},
Doi = {10.1016/j.rssm.2023.100878},
Key = {fds375348}
}
@article{fds371489,
Author = {Boen, CE and Keister, LA and Gibson-Davis, CM and Luck,
A},
Title = {The Buffering Effect of State Eviction and Foreclosure
Policies for Mental Health during the COVID-19 Pandemic in
the United States.},
Journal = {Journal of health and social behavior},
Pages = {221465231175939},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1177/00221465231175939},
Abstract = {The COVID-19 pandemic spurred an economic downturn that may
have eroded population mental health, especially for renters
and homeowners who experienced financial hardship and were
at risk of housing loss. Using household-level data from the
Census Bureau's Household Pulse Survey (n = 805,223; August
2020-August 2021) and state-level data on
eviction/foreclosure bans, we estimated linear probability
models with two-way fixed effects to (1) examine links
between COVID-related financial hardship and
anxiety/depression and (2) assess whether state
eviction/foreclosure bans buffered the detrimental mental
health impacts of financial hardship. Findings show that
individuals who reported difficulty paying for household
expenses and keeping up with rent or mortgage had increased
anxiety and depression risks but that state
eviction/foreclosure bans weakened these associations. Our
findings underscore the importance of state policies in
protecting mental health and suggest that heterogeneity in
state responses may have contributed to mental health
inequities during the pandemic.},
Doi = {10.1177/00221465231175939},
Key = {fds371489}
}
@article{fds368871,
Author = {Gibson-Davis, C and Boen, CE and Keister, LA and Lowell,
W},
Title = {Net worth poverty and adult health.},
Journal = {Social science & medicine (1982)},
Volume = {318},
Pages = {115614},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1016/j.socscimed.2022.115614},
Abstract = {This study broadens the traditional focus on income as the
primary measure of economic deprivation by providing the
first analysis of wealth deprivation, or net worth poverty
(NWP), and adult health. Net worth poverty-having wealth
(assets minus debts) less than one-fourth of the federal
poverty line-likely exacerbates the negative effects of
income poverty (IP). In 2019, one-third of US households
were net worth poor, with substantially higher rates among
Black (60%) relative to White (25%) households. We estimate
longitudinal growth curve (i.e., linear mixed effects)
models to test how NWP, IP, and the interaction of the two
predict a diverse set of health measures. We also consider
whether NWP resulting from either low assets or high debts
is more predictive of health outcomes and test for
heterogeneous associations by race. Data come from Panel
Study of Income Dynamics on 8,962 individuals ages 25 to 64,
observed between 2011 and 2019 (n = 26,776). Adjusting for
income poverty, net worth poverty, relative to no poverty,
was associated with a one-quarter to one-third increase in
the likelihood of reporting poor self-rated health,
psychological distress, and work limitations. Simultaneously
experiencing both NWP and IP was associated with the largest
deficits. Both asset-driven (low asset) and debt-driven
(high debt) NWP reduced health, but asset-driven NWP had
stronger associations (e.g., a 5-percentage point increase
of being in poor health, twice that of debt-driven). White,
relative to Black, adults exhibited statistically larger
associations for psychological distress (4.3 vs 1.1
percentage points) and work limitations (3.7 vs. 1.5
percentage points). White and Black adults who were jointly
net worth and income poor exhibited the most disadvantage.
Findings underscore how wealth is a critical component of
financial deprivation and that wealth deprivation,
particularly the lack of assets, merits attention in
socioeconomic studies of health inequalities.},
Doi = {10.1016/j.socscimed.2022.115614},
Key = {fds368871}
}
@article{fds371572,
Author = {Nur, AA and Leibbrand, C and Curran, SR and Votruba-Drzal, E and Gibson-Davis, C},
Title = {Managing and minimizing online survey questionnaire fraud:
lessons from the Triple C project},
Journal = {International Journal of Social Research
Methodology},
Pages = {1-7},
Publisher = {Informa UK Limited},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/13645579.2023.2229651},
Abstract = {With the increasing sophistication of online survey tools
and the necessity of distanced research during the COVID-19
pandemic, the use of online questionnaires for research
purposes has proliferated. Still, many researchers undertake
online survey research without knowledge of the prevalence
and likelihood of experiencing survey questionnaire fraud
nor familiarity with measures used to identify fraud once it
has occurred. This research note is based on the experience
of researchers across four sites who implemented an online
survey of families’ experiences with COVID-19 in the U.S.
that was subject to substantial fraud. By the end of data
collection, over 70% of responses were flagged as fraudulent
with duplicate IP addresses and concurrent start/end times
representing the most common indicators of fraud observed.
We offer lessons learned to illustrate the sophisticated
nature of fraud in online research and the importance of
multi-pronged strategies to detect and limit online survey
questionnaire fraud.},
Doi = {10.1080/13645579.2023.2229651},
Key = {fds371572}
}
%% Goldston, David B.
@article{fds369355,
Author = {Goldston, DB and Walrath, C},
Title = {The Garrett Lee Smith Memorial Act: A Description and Review
of the Suicide Prevention Initiative.},
Journal = {Annu Rev Clin Psychol},
Volume = {19},
Pages = {261-275},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1146/annurev-clinpsy-080921-082634},
Abstract = {The Garrett Lee Smith (GLS) Memorial Act, continuously
funded since 2004, has supported comprehensive,
community-based youth suicide prevention efforts throughout
the United States. Compared to matched communities,
communities implementing GLS suicide prevention activities
have lower population rates of suicide attempts and lower
mortality among young people. Positive outcomes have been
more pronounced with continuous years of implementation and
in less densely populated communities. Cost analyses
indicate that implementation of GLS suicide prevention
activities more than pays for itself in reduced health care
costs associated with fewer emergency department visits and
hospitalizations. Although findings are encouraging, the
heterogeneity of community suicide prevention programs and
the lack of randomized trials preclude definitive
determination of causal effects associated with GLS. The GLS
initiative has never been brought fully to scale (e.g.,
simultaneously impacting all communities in the United
States), so beneficial effects on nationwide suicide rates
have not been realized.},
Doi = {10.1146/annurev-clinpsy-080921-082634},
Key = {fds369355}
}
@article{fds362120,
Author = {Kauten, RL and Carter, SP and Stivers, M and Novak, LA and Baer, MM and LaCroix, JM and Grant, NE and Sickmann, B and Goldston, DB and Soumoff,
A and Ghahramanlou-Holloway, M},
Title = {Post-Admission Cognitive Therapy for a Transgender Service
Member With a Recent Suicidal Crisis: A Case Study of
Gender-Affirming Care},
Journal = {Cognitive and Behavioral Practice},
Volume = {30},
Number = {2},
Pages = {273-286},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1016/j.cbpra.2021.10.007},
Abstract = {While elevated suicide risk in the American military and
veteran population has led to the development of targeted
interventions, the increased risk of suicidal ideation and
behavior among transgender and gender diverse (TGD) Service
members requires that interventions address suicide risk
within the context of minority stressors and
gender-affirming care. This case study presents Jordan (an
alias), a transgender Service member who received inpatient
psychiatric treatment following a suicide attempt
precipitated by distress relating to gender dysphoria,
minority status, and associated stressors. Jordan completed
Post-Admission Cognitive Therapy (PACT; Ghahramanlou-Holloway,
Cox, & Greene, 2012), a cognitive-behavioral intervention
targeting suicide risk among military personnel and
dependents psychiatrically hospitalized following a suicidal
crisis. Within the context of PACT, Jordan's treatment
included identifying and addressing distress related to
minority stressors (externalized stigma, internalized
transphobia, anticipated rejection, gender concealment)
using gender-affirming best practices. Marked changes in
Jordan's self-report measures from baseline to follow-up, as
well as qualitative changes reported by Jordan, demonstrate
that she felt comfortable, safe, and ready to be discharged
from the inpatient unit after completing PACT treatment and
gaining exposure to the skills necessary to help prevent
and/or manage future suicidal crises. Treatment implications
and recommendations for addressing suicide risk within the
context of gender-affirming care and prevalent minority
stressors are discussed.},
Doi = {10.1016/j.cbpra.2021.10.007},
Key = {fds362120}
}
@article{fds369857,
Author = {Knettel, BA and Knippler, E and Martinez, A and Sardana, S and Agor, D and Mwobobia, J and Ledbetter, L and Amiri, I and Relf, MV and Goldston,
DB},
Title = {A scoping review of counseling interventions for suicide
prevention in Africa: Few studies address this life-saving
aspect of mental health treatment.},
Journal = {J Affect Disord},
Volume = {328},
Pages = {183-190},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1016/j.jad.2023.02.038},
Abstract = {BACKGROUND: Nearly 800,000 people die by suicide each year,
with 77 % occurring in low- and middle-income countries.
Suicide is underestimated in many African settings due to
challenges in data collection, stigma, and policies that
promote silence; nonetheless, rates of suicide in Africa are
consistently higher than global averages. METHODS: We
conducted a scoping review of counseling interventions
assessing suicide outcomes among adults in Africa using
MEDLINE, Embase, PsycINFO, African Index Medicus, CABI
Global Health, and Proquest databases. Study screening and
data extraction was informed by the JBI Manual for Evidence
Synthesis. RESULTS: Of 2438 abstracts reviewed, 33 studies
met criteria for full-text review and 13 were included in
the analysis. Interventions served several populations,
including people living with HIV, out of school youth,
university students, and women undergoing obstetric fistula
repair. There was a near-equal split in individual versus
group counseling modalities and the use of professional
versus lay counselors. The majority of interventions had
primary outcomes focused on other mental health or social
variables with a secondary focus on suicide. Mechanisms of
change for suicide prevention were poorly articulated.
LIMITATIONS: The review was limited to English-language
studies conducted after 2001 and excluded qualitative
studies and those with fewer than 10 participants.
CONCLUSIONS: There is a clear paucity of research in this
area, particularly in the lack of randomized clinical trials
and studies with suicide prevention as their primary
outcome. Researchers should seek to develop or adapt
evidence-based, culturally-resonant interventions to reduce
the burden of suicide on the African continent.},
Doi = {10.1016/j.jad.2023.02.038},
Key = {fds369857}
}
@article{fds370049,
Author = {Miller, VE and Pence, BW and Fitch, KV and Swilley-Martinez, M and Kavee, AL and Dorris, S and Cooper, T and Keil, AP and Gaynes, BN and Carey, TS and Goldston, D and Ranapurwala, S},
Title = {Hurricane Florence and suicide mortality in North Carolina:
a controlled interrupted time-series analysis.},
Journal = {Injury Prevention : Journal of the International Society for
Child and Adolescent Injury Prevention},
Volume = {29},
Number = {2},
Pages = {180-185},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1136/ip-2022-044709},
Abstract = {<h4>Background</h4>Natural disasters are associated with
increased mental health disorders and suicidal ideation;
however, associations with suicide deaths are not well
understood. We explored how Hurricane Florence, which made
landfall in September 2018, may have impacted suicide deaths
in North Carolina (NC).<h4>Methods</h4>We used publicly
available NC death records data to estimate associations
between Hurricane Florence and monthly suicide death rates
using a controlled, interrupted time series analysis.
Hurricane exposure was determined by using county-level
support designations from the Federal Emergency Management
Agency. We examined effect modification by sex, age group,
and race/ethnicity.<h4>Results</h4>8363 suicide deaths
occurred between January 2014 and December 2019. The overall
suicide death rate in NC between 2014 and 2019 was 15.53 per
100 000 person-years (95% CI 15.20 to 15.87).
Post-Hurricane, there was a small, immediate increase in the
suicide death rate among exposed counties (0.89/100 000 PY;
95% CI -2.69 to 4.48). Comparing exposed and unexposed
counties, there was no sustained post-Hurricane Florence
change in suicide death rate trends (0.02/100 000 PY per
month; 95% CI -0.33 to 0.38). Relative to 2018, NC
experienced a statewide decline in suicides in 2019. An
immediate increase in suicide deaths in Hurricane-affected
counties versus Hurricane-unaffected counties was observed
among women, people under age 65 and non-Hispanic black
individuals, but there was no sustained change in the months
after Hurricane Florence.<h4>Conclusions</h4>Although
results did not indicate a strong post-Hurricane Florence
impact on suicide rates, subgroup analysis suggests
differential impacts of Hurricane Florence on several
groups, warranting future follow-up.},
Doi = {10.1136/ip-2022-044709},
Key = {fds370049}
}
@article{fds369952,
Author = {Pisani, A and Connor, K and Van Orden and K and Jordan, N and Landes, S and Curran, G and McDermott, M and Ertefaie, A and Kelberman, C and Ramanathan, S and Carruthers, J and Mossgraber, K and Goldston,
D},
Title = {Effectiveness of a targeted brief intervention for recent
suicide attempt survivors: a randomised controlled trial
protocol.},
Journal = {Bmj Open},
Volume = {13},
Number = {3},
Pages = {e070105},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1136/bmjopen-2022-070105},
Abstract = {INTRODUCTION: Effective, brief, low-cost interventions for
suicide attempt survivors are essential to saving lives and
achieving the goals of the National Strategy for Suicide
Prevention and Zero Suicide. This study aims to examine the
effectiveness of the Attempted Suicide Short Intervention
Program (ASSIP) in averting suicide reattempts in the United
States healthcare system, its psychological mechanisms as
predicted by the Interpersonal Theory of Suicide, and the
potential implementation costs, barriers and facilitators
for delivering it. METHODS AND ANALYSIS: This study is a
hybrid type 1 effectiveness-implementation randomised
controlled trial (RCT). ASSIP is delivered at three
outpatient mental healthcare clinics in New York State.
Participant referral sites include three local hospitals
with inpatient and comprehensive psychiatric emergency
services, and outpatient mental health clinics. Participants
include 400 adults who have had a recent suicide attempt.
All are randomised to 'Zero Suicide-Usual Care plus ASSIP'
or 'Zero Suicide-Usual Care'. Randomisation is stratified by
sex and whether the index attempt is a first suicide attempt
or not. Participants complete assessments at baseline, 6
weeks, and 3, 6, 12 and, 18 months. The primary outcome is
the time from randomisation to the first suicide reattempt.
Prior to the RCT, a 23-person open trial took place, in
which 13 participants received 'Zero Suicide-Usual Care plus
ASSIP' and 14 completed the first follow-up time point.
ETHICS AND DISSEMINATION: This study is overseen by the
University of Rochester, with single Institutional Review
Board (#3353) reliance agreements from Nathan Kline
Institute (#1561697) and SUNY Upstate Medical University
(#1647538). It has an established Data and Safety Monitoring
Board. Results will be published in peer-reviewed academic
journals, presented at scientific conferences, and
communicated to referral organisations. Clinics considering
ASSIP may use a stakeholder report generated by this study,
including incremental cost-effectiveness data from the
provider point of view. TRIAL REGISTRATION NUMBER:
NCT03894462.},
Doi = {10.1136/bmjopen-2022-070105},
Key = {fds369952}
}
@article{fds368128,
Author = {Novak, LA and LaCroix, JM and Perera, KU and Stivers, M and Schvey, NA and Goodie, JL and Olsen, C and Sbrocco, T and Goldston, DB and Soumoff, A and Weaver, J and Ghahramanlou-Holloway, M},
Title = {Help-seeking among psychiatrically hospitalized military
personnel at risk for suicide.},
Journal = {Suicide and Life Threatening Behavior},
Volume = {53},
Number = {1},
Pages = {75-88},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1111/sltb.12923},
Abstract = {INTRODUCTION: Promoting help-seeking is a key suicide
prevention strategy. Yet, research on help-seeking patterns
by high-risk individuals is limited. This study examined
help-seeking among United States military Service members
admitted for psychiatric inpatient care. METHODS:
Participants were active duty Service members (N = 111)
psychiatrically hospitalized for a suicide-related event.
Data were collected as part of a larger randomized
controlled trial. Reported types and perceived helpfulness
of resources sought 30 days before hospitalization were
examined. Hierarchical binary logistic regressions were used
to examine associations among types of helping resources,
mental health treatment stigma, and perceived social
support. RESULTS: Approximately 90% of participants sought
help prior to hospitalization, most frequently from
behavioral health providers and friends. Accessed resources
were generally considered helpful. Adjusting for covariates,
mental health treatment stigma was not associated with
seeking help from any resource type. Higher perceived social
support was associated with greater likelihood of
help-seeking from a friend (OR = 1.08, p = 0.013 [95%
CI = 1.02, 1.14]). Marital status, education level, and
organizational barriers were associated with specific types
of resources, and/or not seeking help. CONCLUSION:
Help-seeking is a complex human behavior. Promoting
help-seeking among vulnerable subgroups requires further
understanding of multiple interconnected
factors.},
Doi = {10.1111/sltb.12923},
Key = {fds368128}
}
@article{fds367390,
Author = {Sun, D and Adduru, VR and Phillips, RD and Bouchard, HC and Sotiras, A and Michael, AM and Baker, FC and Tapert, SF and Brown, SA and Clark, DB and Goldston, D and Nooner, KB and Nagel, BJ and Thompson, WK and De Bellis,
MD and Morey, RA},
Title = {Adolescent alcohol use is linked to disruptions in
age-appropriate cortical thinning: an unsupervised machine
learning approach.},
Journal = {Neuropsychopharmacology},
Volume = {48},
Number = {2},
Pages = {317-326},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1038/s41386-022-01457-4},
Abstract = {Cortical thickness changes dramatically during development
and is associated with adolescent drinking. However,
previous findings have been inconsistent and limited by
region-of-interest approaches that are underpowered because
they do not conform to the underlying spatially
heterogeneous effects of alcohol. In this study, adolescents
(n = 657; 12-22 years at baseline) from the National
Consortium on Alcohol and Neurodevelopment in Adolescence
(NCANDA) study who endorsed little to no alcohol use at
baseline were assessed with structural magnetic resonance
imaging and followed longitudinally at four yearly
intervals. Seven unique spatial patterns of covarying
cortical thickness were obtained from the baseline scans by
applying an unsupervised machine learning method called
non-negative matrix factorization (NMF). The cortical
thickness maps of all participants' longitudinal scans were
projected onto vertex-level cortical patterns to obtain
participant-specific coefficients for each pattern. Linear
mixed-effects models were fit to each pattern to investigate
longitudinal effects of alcohol consumption on cortical
thickness. We found in six NMF-derived cortical thickness
patterns, the longitudinal rate of decline in no/low
drinkers was similar for all age cohorts. Among moderate
drinkers the decline was faster in the younger adolescent
cohort and slower in the older cohort. Among heavy drinkers
the decline was fastest in the younger cohort and slowest in
the older cohort. The findings suggested that unsupervised
machine learning successfully delineated spatially
coordinated patterns of vertex-level cortical thickness
variation that are unconstrained by neuroanatomical
features. Age-appropriate cortical thinning is more rapid in
younger adolescent drinkers and slower in older adolescent
drinkers, an effect that is strongest among heavy
drinkers.},
Doi = {10.1038/s41386-022-01457-4},
Key = {fds367390}
}
@article{fds369858,
Author = {Yu, SH and Kodish, T and Bear, L and O’Neill, JC and Asarnow, JR and Goldston, DB and Cheng, KK and Wang, X and Vargas, SM and Lau,
AS},
Title = {Leader and Provider Perspectives on Implementing Safe
Alternatives for Teens and Youth—Acute (SAFETY-A) in
Public School Districts Serving Racial/Ethnic Minoritized
Youth},
Journal = {School Mental Health},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1007/s12310-023-09572-3},
Abstract = {Racial/ethnic minoritized (REM) youth represent a high-risk
group for suicide, yet there are striking disparities in
their use of mental health services (MHS) even after risk is
identified in schools. Prior research suggests that
school-based risk assessments and hospitalization encounters
can be negatively experienced by REM youth and families,
thus deterring likelihood of seeking follow-up care. The
Safe Alternatives for Teens and Youth-Acute (SAFETY-A) is a
brief, strengths-based, cognitive-behavioral family
intervention demonstrated to increase linkage to MHS when
implemented in emergency departments. With its focus on
strengths and family engagement, SAFETY-A may cultivate a
positive therapeutic encounter suited to addressing
disparities in MHS by enhancing trust and family
collaboration, if appropriately adapted for schools.
Thirty-seven school district leaders and frontline school
MHS providers from districts serving primarily
socioeconomically disadvantaged REM communities participated
in key informant interviews and focus groups. First,
interviews were conducted to understand usual care processes
for responding to students with suicidal thoughts and
behaviors and perspectives on the strengths and
disadvantages of current practices. An as-is process
analysis was used to describe current practices spanning
risk assessment, crisis intervention, and follow-up. Second,
focus groups were conducted to solicit perceptions of the
fit of SAFETY-A for these school contexts. Thematic analysis
of the interviews and focus groups was used to identify
multilevel facilitators and barriers to SAFETY-A
implementation and potential tailoring variables for
implementation strategies across school districts.},
Doi = {10.1007/s12310-023-09572-3},
Key = {fds369858}
}
@article{fds365284,
Author = {Grove, JL and Kimbrel, NA and Griffin, SC and Halverson, T and White,
MA and Blakey, SM and Beckham, JC and Dedert, EA and Goldston, DB and Pugh,
MJ and Calhoun, PS},
Title = {Cannabis use and suicide risk among Gulf War
veterans.},
Journal = {Death Stud},
Volume = {47},
Number = {5},
Pages = {618-623},
Year = {2023},
url = {http://dx.doi.org/10.1080/07481187.2022.2108944},
Abstract = {Cannabis use has been indicated as a risk factor for suicide
in veterans. This study of Gulf War veterans tested the
relationship between self-report past year cannabis use and
(a) past year suicidal ideation and (b) risk for suicidal
behavior. Data were from a national sample (N = 1126) of
Gulf War veterans. Logistic regression models indicated
cannabis use was associated with past year suicidal ideation
and elevated risk for suicidal behavior, independent of key
covariates. In corroboration with research on other military
populations, this study indicates a potentially concerning
association between cannabis use and suicide risk in Gulf
War veterans.},
Doi = {10.1080/07481187.2022.2108944},
Key = {fds365284}
}
%% Groh, Jennifer M.
@article{fds376302,
Author = {Schmehl, MN and Caruso, VC and Chen, Y and Jun, NY and Willett, SM and Mohl, JT and Ruff, DA and Cohen, M and Ebihara, AF and Freiwald, WA and Tokdar, ST and Groh, JM},
Title = {Multiple objects evoke fluctuating responses in several
regions of the visual pathway.},
Journal = {eLife},
Volume = {13},
Pages = {e91129},
Publisher = {eLife Sciences Publications, Ltd},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.7554/elife.91129},
Abstract = {How neural representations preserve information about
multiple stimuli is mysterious. Because tuning of individual
neurons is coarse (e.g., visual receptive field diameters
can exceed perceptual resolution), the populations of
neurons potentially responsive to each individual stimulus
can overlap, raising the question of how information about
each item might be segregated and preserved in the
population. We recently reported evidence for a potential
solution to this problem: when two stimuli were present,
some neurons in the macaque visual cortical areas V1 and V4
exhibited fluctuating firing patterns, as if they responded
to only one individual stimulus at a time (Jun et al.,
2022). However, whether such an information encoding
strategy is ubiquitous in the visual pathway and thus could
constitute a general phenomenon remains unknown. Here, we
provide new evidence that such fluctuating activity is also
evoked by multiple stimuli in visual areas responsible for
processing visual motion (middle temporal visual area, MT),
and faces (middle fundus and anterolateral face patches in
inferotemporal cortex - areas MF and AL), thus extending the
scope of circumstances in which fluctuating activity is
observed. Furthermore, consistent with our previous results
in the early visual area V1, MT exhibits fluctuations
between the representations of two stimuli when these form
distinguishable objects but not when they fuse into one
perceived object, suggesting that fluctuating activity
patterns may underlie visual object formation. Taken
together, these findings point toward an updated model of
how the brain preserves sensory information about multiple
stimuli for subsequent processing and behavioral
action.},
Doi = {10.7554/elife.91129},
Key = {fds376302}
}
@article{fds374233,
Author = {King, CD and Lovich, SN and Murphy, DL and Landrum, R and Kaylie, D and Shera, CA and Groh, JM},
Title = {Individual similarities and differences in
eye-movement-related eardrum oscillations
(EMREOs).},
Journal = {Hear Res},
Volume = {440},
Pages = {108899},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1016/j.heares.2023.108899},
Abstract = {We recently discovered a unique type of otoacoustic emission
(OAE) time-locked to the onset (and offset) of saccadic eye
movements and occurring in the absence of external sound
(Gruters et al., 2018). How and why these
eye-movement-related eardrum oscillations (EMREOs) are
generated is unknown, with a role in visual-auditory
integration being the likeliest candidate. Clues to both the
drivers of EMREOs and their purpose can be gleaned by
examining responses in normal hearing human subjects. Do
EMREOs occur in all individuals with normal hearing? If so,
what components of the response occur most consistently?
Understanding which attributes of EMREOs are similar across
participants and which show more variability will provide
the groundwork for future comparisons with individuals with
hearing abnormalities affecting the ear's various motor
components. Here we report that in subjects with normal
hearing thresholds and normal middle ear function, all ears
show (a) measurable EMREOs (mean: 58.7 dB SPL; range
45-67 dB SPL for large contralateral saccades), (b) a phase
reversal for contra- versus ipsilaterally-directed saccades,
(c) a large peak in the signal occurring soon after saccade
onset, (d) an additional large peak time-locked to saccade
offset and (e) evidence that saccade duration is encoded in
the signal. We interpret the attributes of EMREOs that are
most consistent across subjects as the ones that are most
likely to play an essential role in their function. The
individual differences likely reflect normal variation in
individuals' auditory system anatomy and physiology, much
like traditional measures of auditory function such as
auditory-evoked OAEs, tympanometry and auditory-evoked
potentials. Future work will compare subjects with different
types of auditory dysfunction to population data from normal
hearing subjects. Overall, these findings provide important
context for the widespread observations of visual- and
eye-movement related signals found in cortical and
subcortical auditory areas of the brain.},
Doi = {10.1016/j.heares.2023.108899},
Key = {fds374233}
}
@article{fds374232,
Author = {Lovich, SN and King, CD and Murphy, DLK and Landrum, RE and Shera, CA and Groh, JM},
Title = {Parametric information about eye movements is sent to the
ears.},
Journal = {Proceedings of the National Academy of Sciences of the
United States of America},
Volume = {120},
Number = {48},
Pages = {e2303562120},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1073/pnas.2303562120},
Abstract = {Eye movements alter the relationship between the visual and
auditory spatial scenes. Signals related to eye movements
affect neural pathways from the ear through auditory cortex
and beyond, but how these signals contribute to computing
the locations of sounds with respect to the visual scene is
poorly understood. Here, we evaluated the information
contained in eye movement-related eardrum oscillations
(EMREOs), pressure changes recorded in the ear canal that
occur in conjunction with simultaneous eye movements. We
show that EMREOs contain parametric information about
horizontal and vertical eye displacement as well as
initial/final eye position with respect to the head. The
parametric information in the horizontal and vertical
directions can be modeled as combining linearly, allowing
accurate prediction of the EMREOs associated with oblique
(diagonal) eye movements. Target location can also be
inferred from the EMREO signals recorded during eye
movements to those targets. We hypothesize that the
(currently unknown) mechanism underlying EMREOs could impose
a two-dimensional eye-movement-related transfer function on
any incoming sound, permitting subsequent processing stages
to compute the positions of sounds in relation to the visual
scene.},
Doi = {10.1073/pnas.2303562120},
Key = {fds374232}
}
@article{fds372265,
Author = {Lovich, SN and King, CD and Murphy, DLK and Abbasi, H and Bruns, P and Shera, CA and Groh, JM},
Title = {Conserved features of eye movement related eardrum
oscillations (EMREOs) across humans and monkeys.},
Journal = {Philosophical transactions of the Royal Society of London.
Series B, Biological sciences},
Volume = {378},
Number = {1886},
Pages = {20220340},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1098/rstb.2022.0340},
Abstract = {Auditory and visual information involve different coordinate
systems, with auditory spatial cues anchored to the head and
visual spatial cues anchored to the eyes. Information about
eye movements is therefore critical for reconciling visual
and auditory spatial signals. The recent discovery of eye
movement-related eardrum oscillations (EMREOs) suggests that
this process could begin as early as the auditory periphery.
How this reconciliation might happen remains poorly
understood. Because humans and monkeys both have mobile eyes
and therefore both must perform this shift of reference
frames, comparison of the EMREO across species can provide
insights to shared and therefore important parameters of the
signal. Here we show that rhesus monkeys, like humans, have
a consistent, significant EMREO signal that carries
parametric information about eye displacement as well as
onset times of eye movements. The dependence of the EMREO on
the horizontal displacement of the eye is its most
consistent feature, and is shared across behavioural tasks,
subjects and species. Differences chiefly involve the
waveform frequency (higher in monkeys than in humans) and
patterns of individual variation (more prominent in monkeys
than in humans), and the waveform of the EMREO when factors
due to horizontal and vertical eye displacements were
controlled for. This article is part of the theme issue
'Decision and control processes in multisensory
perception'.},
Doi = {10.1098/rstb.2022.0340},
Key = {fds372265}
}
@article{fds369951,
Author = {King, CD and Lovich, SN and Murphy, DLK and Landrum, R and Kaylie, D and Shera, CA and Groh, JM},
Title = {Individual similarities and differences in
eye-movement-related eardrum oscillations
(EMREOs).},
Journal = {bioRxiv},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1101/2023.03.09.531896},
Abstract = {We recently discovered a unique type of low-frequency
otoacoustic emission (OAE) time-locked to the onset (and
offset) of saccadic eye movements and occurring in the
absence of external sound (Gruters et al., 2018). How and
why these eye-movement-related eardrum oscillations (EMREOs)
are generated is unknown, with a role in visual-auditory
integration being the likeliest candidate. Clues to both the
drivers of EMREOs and their purpose can be gleaned by
examining responses in normal hearing human subjects. Do
EMREOs occur in all individuals with normal hearing? If so,
what components of the response occur most consistently?
Understanding which attributes of EMREOs are similar across
participants and which show more variability will provide
the groundwork for future comparisons with individuals with
hearing abnormalities affecting the ear's various motor
components. Here we report that in subjects with normal
hearing thresholds and normal middle ear function, all ears
show (a) measurable EMREOs (mean: 58.7 dB SPL; range 45-67
dB SPL for large contralateral saccades), (b) a phase
reversal for contra- versus ipsilaterally-directed saccades,
(c) a large peak in the signal occurring soon after saccade
onset, (d) an additional large peak time-locked to saccade
offset and (e) evidence that saccade duration is encoded in
the signal. We interpret the attributes of EMREOs that are
most consistent across subjects as the ones that are most
likely to play an essential role in their function. The
individual differences likely reflect normal variation in
individuals' auditory system anatomy and physiology, much
like traditional measures of auditory function such as
auditory-evoked OAEs, tympanometry and auditory-evoked
potentials. Future work will compare subjects with different
types of auditory dysfunction to population data from normal
hearing subjects. Overall, these findings provide important
context for the widespread observations of visual- and
eye-movement related signals found in cortical and
subcortical auditory areas of the brain.},
Doi = {10.1101/2023.03.09.531896},
Key = {fds369951}
}
@article{fds369950,
Author = {Lovich, SN and King, CD and Murphy, DLK and Abbasi, H and Bruns, P and Shera, CA and Groh, J},
Title = {Conserved features of eye movement related eardrum
oscillations (EMREOs) across humans and monkeys.},
Journal = {bioRxiv},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1101/2023.03.08.531768},
Abstract = {Auditory and visual information involve different coordinate
systems, with auditory spatial cues anchored to the head and
visual spatial cues anchored to the eyes. Information about
eye movements is therefore critical for reconciling visual
and auditory spatial signals. The recent discovery of eye
movement-related eardrum oscillations (EMREOs) suggests that
this process could begin as early as the auditory periphery.
How this reconciliation might happen remains poorly
understood. Because humans and monkeys both have mobile eyes
and therefore both must perform this shift of reference
frames, comparison of the EMREO across species can provide
insights to shared and therefore important parameters of the
signal. Here we show that rhesus monkeys, like humans, have
a consistent, significant EMREO signal that carries
parametric information about eye displacement as well as
onset times of eye movements. The dependence of the EMREO on
the horizontal displacement of the eye is its most
consistent feature, and is shared across behavioral tasks,
subjects, and species. Differences chiefly involve the
waveform frequency (higher in monkeys than in humans) and
patterns of individual variation (more prominent in monkeys
than humans), and the waveform of the EMREO when factors due
to horizontal and vertical eye displacements were controlled
for.},
Doi = {10.1101/2023.03.08.531768},
Key = {fds369950}
}
%% Hard, Bridgette M.
@article{fds367838,
Author = {Kalkstein, DA and Hook, CJ and Hard, BM and Walton,
GM},
Title = {Social norms govern what behaviors come to mind-And what do
not.},
Journal = {Journal of personality and social psychology},
Volume = {124},
Number = {6},
Pages = {1203-1229},
Publisher = {American Psychological Association (APA)},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1037/pspi0000412},
Abstract = {It is well known that norms influence behavior. Beyond
simply shaping what people do, we argue that norms constrain
what behaviors even come to mind as options, effectively
excluding counternormative behaviors from consideration. We
test this hypothesis across five primary and multiple
supplementary studies using diverse methods
(<i>N</i><sub>total</sub> = 5,488). In Study 1, people
reported that behaviors that were counternormative in a
situation, even behaviors that could satisfy a motivational
drive, were far less likely to come to mind and less
desirable than behaviors that were norm-consistent. Going
beyond self-report measures, Studies 2a-2c found that people
even misrepresented norm-violating behaviors as
"impossible," suggesting they are not considered. Using a
change-blindness paradigm, Study 3 found that people were
less likely to track changes in goal-relevant objects that
would be counternormative (vs. normative) to engage with.
Studies 4 and 5 explored implications for problems of
temptation and self-control. Study 4 found that members of a
clinical population striving to eat healthier reported that
the very same unhealthy but tasty food items would be less
tempting and would trigger less self-control conflict if
they encountered the food in a context where its consumption
would be counternormative (vs. normative). Study 5, a field
study, shows that introducing a norm prohibiting laptop use
in class reduced students' temptation to multitask (as well
as actual multitasking) over the term, whereas encouraging
individual self-control did not. Discussion addresses how
norms can be harnessed to lighten the burdens of temptations
and help people achieve their goals. (PsycInfo Database
Record (c) 2023 APA, all rights reserved).},
Doi = {10.1037/pspi0000412},
Key = {fds367838}
}
%% Hare, Brian
@article{fds369844,
Author = {Salomons, H and Smith, KCM and Callahan-Beckel, M and Callahan, M and Levy, K and Kennedy, BS and Bray, EE and Gnanadesikan, GE and Horschler,
DJ and Gruen, M and Tan, J and White, P and vonHoldt, BM and MacLean, EL and Hare, B},
Title = {Response to Hansen Wheat et al.: Additional analysis further
supports the early emergence of cooperative communication in
dogs compared to wolves raised with more human
exposure.},
Journal = {Learning & behavior},
Volume = {51},
Number = {2},
Pages = {131-134},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.3758/s13420-023-00576-2},
Abstract = {Here, we address Hansen Wheat et al.'s commentary in this
journal in response to Salomons et al. Current Biology,
31(14), 3137-3144.E11, (2021). We conduct additional
analyses in response to Hansen Wheat et al.'s two main
questions. First, we examine the claim that it was the move
to a human home environment which enabled the dog puppies to
outperform the wolf puppies in gesture comprehension tasks.
We show that the youngest dog puppies who had not yet been
individually placed in raisers' homes were still highly
skilled, and outperformed similar-aged wolf puppies who had
higher levels of human interaction. Second, we address the
claim that willingness to approach a stranger can explain
the difference between dog and wolf pups' ability to succeed
in gesture comprehension tasks. We explain the various
controls in the original study that render this explanation
insufficient, and demonstrate via model comparison that the
covariance of species and temperament also make this parsing
impossible. Overall, our additional analyses and
considerations support the domestication hypothesis as laid
out by Salomons et al. Current Biology, 31(14),
3137-3144.E11, (2021).},
Doi = {10.3758/s13420-023-00576-2},
Key = {fds369844}
}
%% Hariri, Ahmad
@article{fds372228,
Author = {Lay-Yee, R and Hariri, AR and Knodt, AR and Barrett-Young, A and Matthews, T and Milne, BJ},
Title = {Social isolation from childhood to mid-adulthood: is there
an association with older brain age?},
Journal = {Psychological medicine},
Volume = {53},
Number = {16},
Pages = {7874-7882},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1017/s0033291723001964},
Abstract = {<h4>Background</h4>Older brain age - as estimated from
structural MRI data - is known to be associated with
detrimental mental and physical health outcomes in older
adults. Social isolation, which has similar detrimental
effects on health, may be associated with accelerated brain
aging though little is known about how different
trajectories of social isolation across the life course
moderate this association. We examined the associations
between social isolation trajectories from age 5 to age 38
and brain age assessed at age 45.<h4>Methods</h4>We
previously created a typology of social isolation based on
onset during the life course and persistence into adulthood,
using group-based trajectory analysis of longitudinal data
from a New Zealand birth cohort. The typology comprises four
groups: 'never-isolated', 'adult-only', 'child-only', and
persistent 'child-adult' isolation. A brain age gap estimate
(brainAGE) - the difference between predicted age from
structural MRI date and chronological age - was derived at
age 45. We undertook analyses of brainAGE with trajectory
group as the predictor, adjusting for sex, family
socio-economic status, and a range of familial and
child-behavioral factors.<h4>Results</h4>Older brain age in
mid-adulthood was associated with trajectories of social
isolation after adjustment for family and child confounders,
particularly for the 'adult-only' group compared to the
'never-isolated' group.<h4>Conclusions</h4>Although our
findings are associational, they indicate that preventing
social isolation, particularly in mid-adulthood, may help to
avert accelerated brain aging associated with negative
health outcomes later in life.},
Doi = {10.1017/s0033291723001964},
Key = {fds372228}
}
@article{fds373508,
Author = {Knodt, AR and Elliott, ML and Whitman, ET and Winn, A and Addae, A and Ireland, D and Poulton, R and Ramrakha, S and Caspi, A and Moffitt, TE and Hariri, AR},
Title = {Test-retest reliability and predictive utility of a
macroscale principal functional connectivity
gradient.},
Journal = {Human brain mapping},
Volume = {44},
Number = {18},
Pages = {6399-6417},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1002/hbm.26517},
Abstract = {Mapping individual differences in brain function has been
hampered by poor reliability as well as limited
interpretability. Leveraging patterns of brain-wide
functional connectivity (FC) offers some promise in this
endeavor. In particular, a macroscale principal FC gradient
that recapitulates a hierarchical organization spanning
molecular, cellular, and circuit level features along a
sensory-to-association cortical axis has emerged as both a
parsimonious and interpretable measure of individual
differences in behavior. However, the measurement
reliabilities of this FC gradient have not been fully
evaluated. Here, we assess the reliabilities of both global
and regional principal FC gradient measures using
test-retest data from the young adult Human Connectome
Project (HCP-YA) and the Dunedin Study. Analyses revealed
that the reliabilities of principal FC gradient measures
were (1) consistently higher than those for traditional
edge-wise FC measures, (2) higher for FC measures derived
from general FC (GFC) in comparison with resting-state FC,
and (3) higher for longer scan lengths. We additionally
examined the relative utility of these principal FC gradient
measures in predicting cognition and aging in both datasets
as well as the HCP-aging dataset. These analyses revealed
that regional FC gradient measures and global gradient range
were significantly associated with aging in all three
datasets, and moderately associated with cognition in the
HCP-YA and Dunedin Study datasets, reflecting contractions
and expansions of the cortical hierarchy, respectively.
Collectively, these results demonstrate that measures of the
principal FC gradient, especially derived using GFC,
effectively capture a reliable feature of the human brain
subject to interpretable and biologically meaningful
individual variation, offering some advantages over
traditional edge-wise FC measures in the search for
brain-behavior associations.},
Doi = {10.1002/hbm.26517},
Key = {fds373508}
}
@article{fds370718,
Author = {Strauman, TJ and Hariri, AR},
Title = {Revising a Self-Regulation Phenotype for Depression Through
Individual Differences in Macroscale Brain
Organization.},
Journal = {Current directions in psychological science},
Volume = {32},
Number = {4},
Pages = {267-275},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1177/09637214221149742},
Abstract = {<i>Self-regulation</i> denotes the processes by which people
initiate, maintain, and control their own thoughts,
behaviors, or emotions to produce a desired outcome or avoid
an undesired outcome. Self-regulation brings the influence
of distal factors such as biology, temperament, and
socialization history onto cognition, motivation, and
behavior. Dysfunction in self-regulation represents a
contributory causal factor for psychopathology. Accordingly,
we previously proposed a risk phenotype model for depression
drawing from regulatory focus theory and traditional
task-based fMRI studies. In this article, we revise and
expand our risk phenotype model using insights from new
methodologies allowing quantification of individual
differences in task-free macroscale brain organization. We
offer a set of hypotheses as examples of how examination of
intrinsic macroscale brain organization can extend and
enrich investigations of self-regulation and depression. In
doing so, we hope to promote a useful heuristic for model
development and for identifying transdiagnostic risk
phenotypes in psychopathology.},
Doi = {10.1177/09637214221149742},
Key = {fds370718}
}
@article{fds371656,
Author = {Whitman, ET and Knodt, AR and Elliott, ML and Abraham, WC and Cheyne, K and Hogan, S and Ireland, D and Keenan, R and Leung, JH and Melzer, TR and Poulton, R and Purdy, SC and Ramrakha, S and Thorne, PR and Caspi, A and Moffitt, TE and Hariri, AR},
Title = {Functional topography of the neocortex predicts covariation
in complex cognitive and basic motor abilities.},
Journal = {Cerebral cortex (New York, N.Y. : 1991)},
Volume = {33},
Number = {13},
Pages = {8218-8231},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1093/cercor/bhad109},
Abstract = {Although higher-order cognitive and lower-order sensorimotor
abilities are generally regarded as distinct and studied
separately, there is evidence that they not only covary but
also that this covariation increases across the lifespan.
This pattern has been leveraged in clinical settings where a
simple assessment of sensory or motor ability (e.g. hearing,
gait speed) can forecast age-related cognitive decline and
risk for dementia. However, the brain mechanisms underlying
cognitive, sensory, and motor covariation are largely
unknown. Here, we examined whether such covariation in
midlife reflects variability in common versus distinct
neocortical networks using individualized maps of functional
topography derived from BOLD fMRI data collected in 769
45-year-old members of a population-representative cohort.
Analyses revealed that variability in basic motor but not
hearing ability reflected individual differences in the
functional topography of neocortical networks typically
supporting cognitive ability. These patterns suggest that
covariation in motor and cognitive abilities in midlife
reflects convergence of function in higher-order neocortical
networks and that gait speed may not be simply a measure of
physical function but rather an integrative index of nervous
system health.},
Doi = {10.1093/cercor/bhad109},
Key = {fds371656}
}
@article{fds362550,
Author = {Cobb, AR and Rubin, M and Stote, DL and Baldwin, BC and Lee, H-J and Hariri, AR and Telch, MJ},
Title = {Hippocampal volume and volume asymmetry prospectively
predict PTSD symptom emergence among Iraq-deployed
soldiers.},
Journal = {Psychological medicine},
Volume = {53},
Number = {5},
Pages = {1906-1913},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1017/s0033291721003548},
Abstract = {<h4>Background</h4>Evidence suggests a link between smaller
hippocampal volume (HV) and post-traumatic stress disorder
(PTSD). However, there has been little prospective research
testing this question directly and it remains unclear
whether smaller HV confers risk or is a consequence of
traumatization and PTSD.<h4>Methods</h4>U.S. soldiers
(<i>N</i> = 107) completed a battery of clinical
assessments, including structural magnetic resonance imaging
pre-deployment. Once deployed they completed monthly
assessments of traumatic-stressors and symptoms. We
hypothesized that smaller HV would potentiate the effects of
traumatic stressors on PTSD symptoms in theater. Analyses
evaluated whether total HV, lateral (right <i>v.</i> left)
HV, or HV asymmetry (right - left) moderated the effects of
stressor-exposure during deployment on PTSD
symptoms.<h4>Results</h4>Findings revealed no interaction
between total HV and average monthly traumatic-stressors on
PTSD symptoms <i>b</i> = -0.028, <i>p</i> = 0.681 [95%
confidence interval (CI) -0.167 to 0.100]. However, in the
context of greater exposure to average monthly traumatic
stressors, greater right HV was associated with fewer PTSD
symptoms <i>b</i> = -0.467, <i>p</i> = 0.023 (95% CI -0.786
to -0.013), whereas greater left HV was unexpectedly
associated with greater PTSD symptoms <i>b</i> = 0.435,
<i>p</i> = 0.024 (95% CI 0.028-0.715).<h4>Conclusions</h4>Our
findings highlight the importance of considering the complex
role of HV, in particular HV asymmetry, in predicting the
emergence of PTSD symptoms in response to war-zone
trauma.},
Doi = {10.1017/s0033291721003548},
Key = {fds362550}
}
@article{fds370934,
Author = {Barrett-Young, A and Abraham, WC and Cheung, CY and Gale, J and Hogan,
S and Ireland, D and Keenan, R and Knodt, AR and Melzer, TR and Moffitt,
TE and Ramrakha, S and Tham, YC and Wilson, GA and Wong, TY and Hariri, AR and Poulton, R},
Title = {Associations Between Thinner Retinal Neuronal Layers and
Suboptimal Brain Structural Integrity in a Middle-Aged
Cohort.},
Journal = {Eye and brain},
Volume = {15},
Pages = {25-35},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.2147/eb.s402510},
Abstract = {<h4>Purpose</h4>The retina has potential as a biomarker of
brain health and Alzheimer's disease (AD) because it is the
only part of the central nervous system which can be easily
imaged and has advantages over brain imaging technologies.
Few studies have compared retinal and brain measurements in
a middle-aged sample. The objective of our study was to
investigate whether retinal neuronal measurements were
associated with structural brain measurements in a
middle-aged population-based cohort.<h4>Participants and
methods</h4>Participants were members of the Dunedin
Multidisciplinary Health and Development Study (n=1037; a
longitudinal cohort followed from birth and at ages 3, 5, 7,
9, 11, 13, 15, 18, 21, 26, 32, 38, and most recently at age
45, when 94% of the living Study members participated).
Retinal nerve fibre layer (RNFL) and ganglion cell-inner
plexiform layer (GC-IPL) thickness were measured by optical
coherence tomography (OCT). Brain age gap estimate
(brainAGE), cortical surface area, cortical thickness,
subcortical grey matter volumes, white matter
hyperintensities, were measured by magnetic resonance
imaging (MRI).<h4>Results</h4>Participants with both MRI and
OCT data were included in the analysis (RNFL n=828, female
n=413 [49.9%], male n=415 [50.1%]; GC-IPL n=825, female
n=413 [50.1%], male n=412 [49.9%]). Thinner retinal neuronal
layers were associated with older brain age, smaller
cortical surface area, thinner average cortex, smaller
subcortical grey matter volumes, and increased volume of
white matter hyperintensities.<h4>Conclusion</h4>These
findings provide evidence that the retinal neuronal layers
reflect differences in midlife structural brain integrity
consistent with increased risk for later AD, supporting the
proposition that the retina may be an early biomarker of
brain health.},
Doi = {10.2147/eb.s402510},
Key = {fds370934}
}
%% Harrell King, Ashley L.
@article{fds369152,
Author = {Harrell, A and Wolff, T},
Title = {Cooperation in Networked Collective-Action Groups:
Information Access and Norm Enforcement in Groups of
Different Sizes},
Journal = {Social Psychology Quarterly},
Volume = {86},
Number = {4},
Pages = {476-496},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1177/01902725221132517},
Abstract = {Norms, typically enforced via sanctions, are key to
resolving collective-action problems. But it is often
impossible to know what each individual member is
contributing to group efforts and enforce cooperation
accordingly. Especially as group size increases, people
commonly have access to the behaviors of—and can
sanction—only those to whom they are tied in a broader
network. Here we integrate two streams of research: one
conceptualizing ties in networked collective-action groups
as access to information about what others are doing and a
second where ties represent information plus opportunities
to enforce cooperation via punishment. While both have
pointed to the cooperation benefits of more ties in the
network, we argue that these benefits will depend on group
size and whether ties provide access to information about
what others are doing or whether they also entail
opportunities for norm enforcement. Our experiment
demonstrates that densely tied information networks
facilitate cooperation but only when the group size is
small. When people can also enforce their ties’
cooperation, however, densely tied networks particularly
benefit larger groups. The results demonstrate how
network-level properties and individual-level tie patterns
intersect to promote contributions in small and large
collective-action groups.},
Doi = {10.1177/01902725221132517},
Key = {fds369152}
}
@article{fds375516,
Author = {Harrell, A and Wolff, T},
Title = {Information-sharing and cooperation in networked collective
action groups},
Journal = {PNAS Nexus},
Volume = {2},
Number = {12},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1093/pnasnexus/pgad399},
Abstract = {When people provide for large-scale public goods, they often
do not know what each individual group member is
contributing. Instead, they commonly have access to the
behaviors of their ties, in a broader network of others
whose decisions are unknown. But network ties also serve as
channels of communication, allowing behaviors to reach a
larger audience. Here, we ask how public good production is
affected in networks when people can share information about
their ties' behaviors with their other connections-and what
behaviors they tend to share. We predict that networked
collective action groups demonstrate higher levels of
cooperation when their members can share information about
their ties' decisions with their other connections, compared
with when they cannot. Informed by prior work, we consider
two pathways by which information-sharing opportunities
might shape cooperation in networked collective action
groups: (i) as a means of coordinating one's own decisions
with those of the larger group, including those to whom one
is not directly tied, and (ii) as a reminder of possible
reputational consequences for selfishness. Across two
exploratory experiments (combined n = 7,014 contribution
decisions, 49 groups), we demonstrate that opportunities to
share information about others' decisions promote public
good production. The benefits occur even though people tend
to share information about relatively selfish behaviors
that, at first blush, might seem detrimental to cooperation.
Our results build on prior work by showing that
information-sharing prevents selfishness from becoming
contagious by raising reputational concerns.},
Doi = {10.1093/pnasnexus/pgad399},
Key = {fds375516}
}
@article{fds370840,
Author = {Harrell, A and Quinn, JM},
Title = {Shared Identities and the Structure of Exchange Distinctly
Shape Cooperation},
Journal = {Social Forces},
Volume = {102},
Number = {1},
Pages = {223-241},
Publisher = {Oxford University Press (OUP)},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1093/sf/soad011},
Abstract = {<jats:title>Abstract</jats:title> <jats:p>People frequently
engage in preferential treatment toward those with whom they
share category memberships. At the same time, sociologists
have long understood that the structure of ongoing relations
shapes micro-level interactions. Here, we ask whether—and
if so, how—same-identity bias in cooperation interacts
with key structural features of exchange relations.
Specifically, we use the affect theory of social exchange
(ATSE) to make predictions about cooperation in productive,
reciprocal, and generalized exchange when people are
embedded in networks where identities are either known and
homogeneous, known and heterogenous, or unknown. Results
from our experiment support both past work demonstrating
same-identity bias in cooperation and the ATSE’s
predictions that productive exchange yields the highest
levels of cooperation and affective attachment, followed by
reciprocal and generalized exchange. More importantly, we
find that shared identities and the structure of exchange
are two orthogonal factors that distinctly promote
cooperation in the presence of each other. Structures with
known homogeneous identities are more cooperative and
develop higher levels of affective attachment across all
forms of exchange, and different types of exchange produce
different levels of cooperation and affective attachment in
line with the ATSE, but the identity and structural
mechanisms do not interact. We conclude by discussing the
theoretical implications of our findings for the ATSE and
scholarship on social identity biases as well as the
practical implications for facilitating cooperation in
diverse groups.</jats:p>},
Doi = {10.1093/sf/soad011},
Key = {fds370840}
}
@article{fds366426,
Author = {Harrell, A and Greenleaf, AS},
Title = {Resource asymmetry reduces generosity and paying forward
generosity, among the resource-advantaged and
disadvantaged.},
Journal = {Social science research},
Volume = {109},
Pages = {102786},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1016/j.ssresearch.2022.102786},
Abstract = {Decisions to benefit others often entail generalized
reciprocity: helping someone who cannot directly return
benefits in the future; instead, the beneficiary may "pay it
forward" to someone else. While much past work demonstrates
that people pay forward generosity, experimental tests of
these processes typically assume that people have equal
access to same-valued resources that they can use to benefit
others. Yet this is rare in daily life, where people
commonly experience asymmetries in the resources that they
have to help others and to pay forward help received. In an
experiment, we find that acts of generalized
reciprocity-including initiating generosity and, upon being
treated generously, paying it forward-are reduced when there
is resource asymmetry between potential benefactors. Results
show that the detriments of resource asymmetry occur among
both the resource-advantaged and the disadvantaged.
Asymmetry in available resources, and inequality more
broadly, is thus critical for understanding patterns of
generosity.},
Doi = {10.1016/j.ssresearch.2022.102786},
Key = {fds366426}
}
%% Howard, Cortney
@article{fds375238,
Author = {Huang, S and Howard, CM and Hovhannisyan, M and Ritchey, M and Cabeza,
R and Davis, SW},
Title = {Hippocampal Functions Modulate Transfer-Appropriate Cortical
Representations Supporting Subsequent Memory.},
Journal = {J Neurosci},
Volume = {44},
Number = {1},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1523/JNEUROSCI.1135-23.2023},
Abstract = {The hippocampus plays a central role as a coordinate system
or index of information stored in neocortical loci.
Nonetheless, it remains unclear how hippocampal processes
integrate with cortical information to facilitate successful
memory encoding. Thus, the goal of the current study was to
identify specific hippocampal-cortical interactions that
support object encoding. We collected fMRI data while 19
human participants (7 female and 12 male) encoded images of
real-world objects and tested their memory for object
concepts and image exemplars (i.e., conceptual and
perceptual memory). Representational similarity analysis
revealed robust representations of visual and semantic
information in canonical visual (e.g., occipital cortex) and
semantic (e.g., angular gyrus) regions in the cortex, but
not in the hippocampus. Critically, hippocampal functions
modulated the mnemonic impact of cortical representations
that are most pertinent to future memory demands, or
transfer-appropriate representations Subsequent perceptual
memory was best predicted by the strength of visual
representations in ventromedial occipital cortex in
coordination with hippocampal activity and pattern
information during encoding. In parallel, subsequent
conceptual memory was best predicted by the strength of
semantic representations in left inferior frontal gyrus and
angular gyrus in coordination with either hippocampal
activity or semantic representational strength during
encoding. We found no evidence for transfer-incongruent
hippocampal-cortical interactions supporting subsequent
memory (i.e., no hippocampal interactions with cortical
visual/semantic representations supported
conceptual/perceptual memory). Collectively, these results
suggest that diverse hippocampal functions flexibly modulate
cortical representations of object properties to satisfy
distinct future memory demands.Significance Statement The
hippocampus is theorized to index pieces of information
stored throughout the cortex to support episodic memory. Yet
how hippocampal processes integrate with cortical
representation of stimulus information remains unclear.
Using fMRI, we examined various forms of
hippocampal-cortical interactions during object encoding in
relation to subsequent performance on conceptual and
perceptual memory tests. Our results revealed novel
hippocampal-cortical interactions that utilize semantic and
visual representations in transfer-appropriate manners:
conceptual memory supported by hippocampal modulation of
frontoparietal semantic representations, and perceptual
memory supported by hippocampal modulation of occipital
visual representations. These findings provide important
insights into the neural mechanisms underlying the formation
of information-rich episodic memory and underscore the value
of studying the flexible interplay between brain regions for
complex cognition.},
Doi = {10.1523/JNEUROSCI.1135-23.2023},
Key = {fds375238}
}
%% Hoyle, Rick
@article{fds375858,
Author = {Andrade, FC and Burnell, K and Godwin, J and Hoyle,
RH},
Title = {Alcohol Use and Abstinence throughout Adolescence: The
Changing Contributions of Perceived Risk of Drinking,
Opportunities to Drink, and Self-Control.},
Journal = {Substance use & misuse},
Volume = {59},
Number = {6},
Pages = {910-919},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1080/10826084.2024.2310489},
Abstract = {<i>Objective</i>: Adolescence is characterized by
psychosocial and cognitive changes that can alter the
perceived risk of negative effects of alcohol, opportunities
to drink, and self-control. Few studies have investigated
whether these factors change in their contribution to
adolescent drinking over time. This study examined
associations between perceived risk, opportunities to drink,
self-control, and past-year drinking and investigated
whether self-control buffers the effect of lower perceived
risk and frequent drinking opportunities on the probability
of past-year drinking. <i>Method</i>: Data from a four-wave
longitudinal study (2015-2020) of 2,104 North Carolina
adolescents (<i>M<sub>age</sub></i> = 12.36,
<i>SD<sub>age</sub></i> = 1.12, at Time 1) were used to
assess changes in associations between self-control,
perceived risk of drinking, and drinking opportunities on
the frequency of past-year drinking. Hypotheses were tested
using latent trajectory models. <i>Results</i>: At all
timepoints, greater perceived risk, fewer drinking
opportunities, and higher self-control were associated with
drinking abstinence in the past year. Self-control buffered
the impact of frequent drinking opportunities and lower
perceived risk on the probability of alcohol use at Times
1-3. <i>Conclusions</i>: Despite expectations that
adolescents' ability to navigate their environments improves
as they age, associations between risk, protective factors,
and past-year drinking were relatively stable over time.
Nevertheless, self-control protected against frequent
drinking opportunities and lower perceived risk. Strategies
that support or relieve the need for self-control (e.g.,
situation modification) may protect against alcohol use
throughout adolescence.},
Doi = {10.1080/10826084.2024.2310489},
Key = {fds375858}
}
@article{fds375859,
Author = {Kwiatek, SM and Cai, L and Cagney, KA and Copeland, WE and Hotz, VJ and Hoyle, RH},
Title = {Comparative assessment of the feasibility and validity of
daily activity space in urban and non-urban
settings.},
Journal = {PLoS One},
Volume = {19},
Number = {1},
Pages = {e0297492},
Year = {2024},
url = {http://dx.doi.org/10.1371/journal.pone.0297492},
Abstract = {Activity space research explores the behavioral impact of
the spaces people move through in daily life. This research
has focused on urban settings, devoting little attention to
non-urban settings. We examined the validity of the activity
space method, comparing feasibility and data quality in
urban and non-urban contexts. Overall, we found that the
method is easily implemented in both settings. We also found
location data quality was comparable across residential and
activity space settings. The major differences in GPS
(Global Positioning System) density and accuracy came from
the operating system (iOS versus Android) of the device
used. The GPS-derived locations showed high agreement with
participants' self-reported locations. We further validated
GPS data by comparing at-home time allocation with the
American Time Use Survey. This study suggests that it is
possible to collect daily activity space data in non-urban
settings that are of comparable quality to data from urban
settings.},
Doi = {10.1371/journal.pone.0297492},
Key = {fds375859}
}
@article{fds368899,
Author = {Andrade, FC and Hoyle, RH and Burnell, K},
Title = {Adjusting to the COVID-19 outbreak in the United States: The
impact of disruptions on habits and changes in health
behaviors.},
Journal = {Journal of health psychology},
Volume = {28},
Number = {14},
Pages = {1307-1319},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1177/13591053221144440},
Abstract = {The COVID-19 pandemic provides a naturalistic test of
whether pandemic-related disruptions weaken habits and
undermine behavior stability. We hypothesized that better
capacity to effortfully guide behavior (self-regulation)
would buffer this effect and be associated with behavior
stability and development of new habits to accomplish daily
behaviors. A cross-sectional study of 416 MTurk workers
recruited in April 2020 (<i>M</i><sub>age</sub> = 34.60,
<i>SD</i> = 11.51) indicated that pandemic-related
disruptions generally exceeded people's capacity to
effortfully modify their behavior. Self-regulation related
to the development of new habits and to lower likelihood
that work productivity decreased. Self-regulation also
protected against the effect of disruption on the likelihood
that substance use increased. Besides these associations,
self-regulation was largely unrelated to health-related
behaviors and, in some instances, associated with poorer
outcomes. These findings underscore the need to appreciate
the impact of contextual disruptions in interpreting and
promoting change in health-related behaviors.},
Doi = {10.1177/13591053221144440},
Key = {fds368899}
}
@article{fds364964,
Author = {Gajos, JM and Russell, MA and Odgers, CL and Hoyle, RH and Copeland,
WE},
Title = {Pubertal timing moderates the same-day coupling between
family hassles and negative affect in girls and
boys.},
Journal = {Dev Psychopathol},
Volume = {35},
Number = {4},
Pages = {1942-1955},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1017/S0954579422000591},
Abstract = {This study examined the association between pubertal timing,
daily affect, conduct problems, and the exposure to hassles
across family, peer, and school contexts. Adolescents (M age
= 12.27; 49.7% female; 62.6% White) completed ecological
momentary assessments across 14 consecutive days (N = 388).
Earlier maturing girls reported lower daily averages of
positive affect compared to their same-sex, same-age peers.
We did not find evidence for a relationship between pubertal
timing and daily negative affect or conduct problems in
girls, nor for daily negative and positive affect or conduct
problems in boys. However, pubertal timing did moderate the
day-level association between average negative affect and
family hassles for both girls and boys. When experiencing
more family hassles, earlier maturing girls reported greater
negative affect relative to later maturing girls who
experienced family hassles. In contrast, later maturing
boys, relative to earlier maturing boys, reported higher
levels of negative affect in the context of family
hassles.},
Doi = {10.1017/S0954579422000591},
Key = {fds364964}
}
@article{fds370881,
Author = {Jongman-Sereno, KP and Hoyle, RH and Davisson, EK and Park,
J},
Title = {Intellectual Humility and Responsiveness to Public Health
Recommendations.},
Journal = {Personality and individual differences},
Volume = {211},
Pages = {112243},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1016/j.paid.2023.112243},
Abstract = {We examined the association between intellectual humility
(IH)-a willingness to consider credible new information and
alternative views and revise one's own views if
warranted-and adherence to experts' health behavior
recommendations in the U.S. during the COVID-19 pandemic.
Study 1 (<i>N</i> = 541) results showed that people higher
in IH are more likely to engage in recommended health
behaviors (e.g., mask-wearing, social distancing)-even when
controlling for political affiliation. Additional analyses
focused specifically on mask-wearing produced initial
evidence consistent with mediation of the IH-mask-wearing
relationship by the beliefs that mask-wearing 1) is an
effective way to slow the spread of COVID-19 and 2) protects
others. Based on the pathway from IH to mask-wearing through
a concern for others found in Study 1, Study 2 further
examined the relationship between IH and prosocial
tendencies. The results from Study 2 (<i>N</i>s for
correlation coefficients ranged from 265 to 702) showed an
association between IH and several values and traits that
reflect a concern for others (e.g., agreeableness,
benevolence). These findings suggest that IH may influence
behavior through both intra- and interpersonal mechanisms.
Implications of these findings for the health-behavior
domain are discussed.},
Doi = {10.1016/j.paid.2023.112243},
Key = {fds370881}
}
@article{fds371263,
Author = {Gehrt, TB and Nielsen, NP and Hoyle, RH and Rubin, DC and Berntsen,
D},
Title = {Narrative identity does not predict well-being when
controlling for emotional valence.},
Journal = {Memory (Hove, England)},
Volume = {31},
Number = {8},
Pages = {1051-1061},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1080/09658211.2023.2218632},
Abstract = {Narrative identity refers to a person's internalized and
evolving life story. It is a rapidly growing research field,
motivated by studies showing a unique association with
well-being. Here we show that this association disappears
when controlling for the emotional valence of the stories
told and individuals' general experience of autobiographical
memory. Participants (<i>N </i>= 235) wrote their life
story and completed questionnaires on their general
experience of autobiographical memory and several dimensions
of well-being and affect. Participants' life stories were
coded for standard narrative identity variables, including
agency and communion. When controlling for emotional valence
of the life story, the general experience of
autobiographical memory was a significant predictor of most
well-being measures, whereas agency was a predictor of one
variable only and communion of none. These findings
contradict the claim of an incremental association between
narrative identity and well-being, and have important
theoretical and practical implications for narrative
identity as an outcome measure in interventions.},
Doi = {10.1080/09658211.2023.2218632},
Key = {fds371263}
}
@article{fds370932,
Author = {Davisson, EK and Hoyle, RH},
Title = {Collective Views of Vaccination Predict Vaccine Hesitancy
and Willingness to Receive a COVID-19 Vaccine.},
Journal = {Social and personality psychology compass},
Volume = {17},
Number = {8},
Pages = {e12768},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1111/spc3.12768},
Abstract = {We examined the association between sociodemographic
factors, views of vaccines as being an individual choice to
protect oneself vs. a collective choice to protect others,
general vaccine hesitancy, and willingness to receive a
COVID-19 vaccine. In a sample of adults (<i>N</i> = 619; 33%
non-white), we showed that demographic factors explain
significant variance in both vaccine hesitancy and
willingness to receive a COVID-19 vaccine. Viewing vaccines
as an individual choice to protect oneself explained
additional variance in vaccine hesitancy. However, people
who viewed vaccines as a collective choice to protect others
showed both less vaccine hesitancy and greater willingness
to receive a COVID-19 vaccine. These findings suggest that
promoting prosocial attitudes about vaccinations may
decrease vaccine hesitancy and increase vaccine
uptake.},
Doi = {10.1111/spc3.12768},
Key = {fds370932}
}
@book{fds372968,
Author = {Hoyle, RH and Davisson, EK},
Title = {Forms of intellectual humility and their associations with
features of knowledge, beliefs, and opinions},
Pages = {101-119},
Booktitle = {Divided: Open-Mindedness and Dogmatism in a Polarized
World},
Year = {2023},
Month = {July},
ISBN = {9780197655467},
url = {http://dx.doi.org/10.1093/oso/9780197655467.003.0006},
Doi = {10.1093/oso/9780197655467.003.0006},
Key = {fds372968}
}
@article{fds370716,
Author = {Hoyle, RH and Davisson, EK},
Title = {Associations between COVID-19-related disruptions and
psychological adjustment in a sample of young
adults},
Journal = {Social and Personality Psychology Compass},
Volume = {17},
Number = {7},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1111/spc3.12750},
Abstract = {We examined the relations between disruptions experienced by
young adults in the US during the COVID-19 pandemic and
their psychological adjustment. An online sample (N = 180,
Mage = 24.8) reported on the impact of the pandemic on
their living arrangements, work status, and finances; their
psychological adjustment overall and with specific reference
to the pandemic; and whether they lived alone and, if living
with others, there were children in the home. Results
indicated a moderate association between financial strain
and poor overall adjustment and a small association between
job-related problems and sleep disruption. Women experienced
negative effects of pandemic-related disruptions on their
adjustment. Men were particularly vulnerable to the negative
effects of financial strain. The results show the negative
psychological effects of disruptions brought about by the
COVID-19 pandemic on young adults' mental
health.},
Doi = {10.1111/spc3.12750},
Key = {fds370716}
}
@article{fds371127,
Author = {Meyerson, WU and Fineberg, SK and Andrade, FC and Corlett, P and Gerstein, MB and Hoyle, RH},
Title = {The association between evening social media use and delayed
sleep may be causal: Suggestive evidence from 120 million
Reddit timestamps.},
Journal = {Sleep medicine},
Volume = {107},
Pages = {212-218},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1016/j.sleep.2023.04.021},
Abstract = {Public health officials and clinicians routinely advise
social media users to avoid nighttime social media use due
to the perception that this delays the onset of sleep and
predisposes to the health risks of insufficient sleep. With
some exceptions, the evidence behind this advice mostly
derives from surveys identifying an association between
self-reported social media usage and self-reported sleep
patterns. In principle, these associations could
alternatively be explained by users turning to social media
to pass the time when they are otherwise having difficulty
sleeping, or by individual differences that draw some people
to frequent social media use, or by offline activities that
overlap with both social media use and delayed sleep. To
attempt to distinguish among these explanations, we
leveraged estimated bedtimes from 44,000 Reddit users
reported in a recent study and their 120 million posts to
test whether the relationship between sleep and social media
has properties suggestive of a causal relationship. We find
that users are especially likely to be active on Reddit
after their bedtime (and therefore awake) on nights that
they posted to Reddit shortly before bedtime, especially if
they posted multiple times or in high-engagement forums that
night. Overall, this study lends additional support to the
notion that there likely is some causal effect of evening
social media use on delayed sleep onset.},
Doi = {10.1016/j.sleep.2023.04.021},
Key = {fds371127}
}
@article{fds370240,
Author = {Gassman-Pines, A and Bellows, L and Copeland, WE and Hoyle, RH and Odgers, CL},
Title = {Day-to-day variation in adolescent food insecurity.},
Journal = {Child Youth Serv Rev},
Volume = {149},
Pages = {106954-106954},
Publisher = {Elsevier BV},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1016/j.childyouth.2023.106954},
Abstract = {This study examined differences in both average and
variability in daily adolescent food insecurity, by
adolescents' levels of economic disadvantage and
race/ethnicity. We used data from a 14-day ecological
momentary assessment of 395 adolescents enrolled in public
schools in North Carolina. Each evening, adolescents were
asked questions about that day's food insecurity.
Economically disadvantaged adolescents reported both higher
average food insecurity and more day-to-day variability in
food insecurity than non-economically disadvantaged
adolescents. Controlling for economic disadvantage, Black
adolescents also experienced both higher average food
insecurity and more variability from day to day than White
or Hispanic adolescents. For those receiving Supplemental
Nutrition Assistance Program (SNAP) benefits, daily food
insecurity was higher in the second half of the month after
SNAP transfer than in the beginning of the month. Food
insecurity among adolescents is not static but varies from
day to day. This daily variation is greater for economically
disadvantaged youth.},
Doi = {10.1016/j.childyouth.2023.106954},
Key = {fds370240}
}
@article{fds370241,
Author = {Burnell, K and Andrade, FC and Kwiatek, SM and Hoyle,
RH},
Title = {Digital location tracking: A preliminary investigation of
parents' use of digital technology to monitor their
adolescent's location.},
Journal = {Journal of family psychology : JFP : journal of the Division
of Family Psychology of the American Psychological
Association (Division 43)},
Volume = {37},
Number = {4},
Pages = {561-567},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1037/fam0001067},
Abstract = {The emergence of digital technologies has changed the
dynamic of parent-adolescent relationships. Parents can now
use digital technologies to monitor their adolescent's
physical location. Yet, to date, no known research has
examined the extent to which digital location tracking
occurs in parent-adolescent dyads, and how tracking links to
adolescent adjustment. The current research examined digital
location tracking in a large sample of adolescents (<i>N</i>
= 729; <i>M</i><sub>age</sub> = 15.03). Overall, about half
of parents and adolescents reported digital location
tracking. Girls and younger adolescents were more likely to
be tracked, and tracking was associated with greater
externalizing problems and alcohol consumption; however,
these associations were not robust across multiple
informants and sensitivity analyses. Positive linkages with
externalizing problems and cannabis use were in part
contingent on age and positive parenting, with associations
emerging for older adolescents and adolescents who report
lower positive parenting. Older adolescents are increasingly
striving for independence and autonomy, and adolescents who
perceive lower positive parenting may view digital tracking
as controlling and intrusive. However, results were not
robust after statistical correction. This brief report is
intended to serve as a preliminary investigation into
digital location tracking, and future research is needed to
determine the directionality of associations. Possible
consequences of parental digital tracking require careful
consideration by researchers in order to provide guidance on
the best practices for engaging in digital monitoring while
nurturing and respecting the parent-adolescent relationship.
(PsycInfo Database Record (c) 2023 APA, all rights
reserved).},
Doi = {10.1037/fam0001067},
Key = {fds370241}
}
@article{fds374170,
Author = {Meyerson, WU and Pieper, CF and Hoyle, RH},
Title = {Use of Quantile Treatment Effects Analysis to Describe
Antidepressant Response in Randomized Clinical Trials
Submitted to the US Food and Drug Administration: A
Secondary Analysis of Pooled Trial Data.},
Journal = {JAMA Netw Open},
Volume = {6},
Number = {6},
Pages = {e2317714},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1001/jamanetworkopen.2023.17714},
Abstract = {IMPORTANCE: Major depressive disorder (MDD) is a leading
cause of global distress and disability. Earlier studies
have indicated that antidepressant therapy confers a modest
reduction in depressive symptoms on average, but the
distribution of this reduction requires more research.
OBJECTIVE: To estimate the distribution of antidepressant
response by depression severity. DESIGN, SETTING, AND
PARTICIPANTS: In this secondary analysis of pooled trial
data, quantile treatment effect (QTE) analysis was conducted
from the US Food and Drug Administration (FDA) database of
antidepressant monotherapy for patients with MDD,
encompassing 232 positive and negative trials submitted to
the FDA between 1979 and 2016. Analysis was restricted to
participants with severe MDD (17-item Hamilton Rating Scale
for Depression [HAMD-17] score ≥20). Data analysis was
conducted from August 16, 2022, to April 16, 2023.
INTERVENTION: Antidepressant monotherapy compared with
placebo. MAIN OUTCOMES AND MEASURES: The distribution of
percentage depression response was compared between the
pooled treatment arm and pooled placebo arm. Percentage
depression response was defined as 1 minus the ratio of
final depression severity to baseline depression severity,
expressed as a percentage. Depression severity was reported
in HAMD-17-equivalent units. RESULTS: A total of 57 313
participants with severe depression were included in the
analysis. There was no significant imbalance in baseline
depression severity between the pooled treatment arm and
pooled placebo arm, with a mean HAMD-17 difference of 0.037
points (P = .11 by Wilcoxon rank sum test). An
interaction term test for rank similarity did not reject the
rank similarity governing percentage depression response
(P > .99). The entire distribution of depression
response was more favorable in the pooled treatment arm than
in the pooled placebo arm. The maximum separation between
treatment and placebo occurred at the 55th quantile and
corresponded to an absolute improvement in depression due to
active drug of 13.5% (95% CI, 12.4%-14.4%). The separation
between treatment and placebo diminished near the tails of
the distribution. CONCLUSIONS AND RELEVANCE: In this QTE
analysis of pooled clinical trial data from the FDA,
antidepressants were found to confer a small reduction in
depression severity that was broadly distributed across
participants with severe depression. Alternatively, if the
assumptions behind the QTE analysis are not met, then the
data are also compatible with antidepressants eliciting more
complete response in a smaller subset of participants than
is suggested by this QTE analysis.},
Doi = {10.1001/jamanetworkopen.2023.17714},
Key = {fds374170}
}
@article{fds370931,
Author = {Hoyle, RH and Lynam, DR and Miller, JD and Pek, J},
Title = {The Questionable Practice of Partialing to Refine Scores on
and Inferences About Measures of Psychological
Constructs.},
Journal = {Annual review of clinical psychology},
Volume = {19},
Pages = {155-176},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1146/annurev-clinpsy-071720-015436},
Abstract = {Partialing is a statistical approach researchers use with
the goal of removing extraneous variance from a variable
before examining its association with other variables.
Controlling for confounds through analysis of covariance or
multiple regression analysis and residualizing variables for
use in subsequent analyses are common approaches to
partialing in clinical research. Despite its intuitive
appeal, partialing is fraught with undesirable consequences
when predictors are correlated. After describing effects of
partialing on variables, we review analytic approaches
commonly used in clinical research to make inferences about
the nature and effects of partialed variables. We then use
two simulations to show how partialing can distort variables
and their relations with other variables. Having concluded
that, with rare exception, partialing is ill-advised, we
offer recommendations for reducing or eliminating
problematic uses of partialing. We conclude that the best
alternative to partialing is to define and measure
constructs so that it is not needed.},
Doi = {10.1146/annurev-clinpsy-071720-015436},
Key = {fds370931}
}
@article{fds367225,
Author = {Burnell, K and Andrade, FC and Hoyle, RH},
Title = {Longitudinal and daily associations between adolescent
self-control and digital technology use.},
Journal = {Developmental psychology},
Volume = {59},
Number = {4},
Pages = {720-732},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1037/dev0001444},
Abstract = {There is fear that adolescents have limited control over
their digital technology use. The current research examines
longitudinal (Study 1) and daily (Study 2) associations
between U.S. adolescents' self-control and digital
technological impairment and use. Using a large sample
(<i>N</i> = 2,104; Wave 1: <i>M</i><sub>age</sub> = 12.36,
52% female, 57% economically disadvantaged, 48% racial
minority), Study 1 tested how changes in adolescents'
self-control and perceived technological impairment co-occur
across time (between-person associations) and if
self-control and perceived impairment are prospectively and
bidirectionally associated with each other (within-person
associations). There was evidence of between-person
associations, in that poorer self-control and perceived
technological impairment both increase over adolescence, and
these increases are positively associated with each other.
However, there was no evidence of prospective within-person
associations. Using a subsample from Study 1 (N = 388),
Study 2 found support for a between-person association for
self-control and using digital technology for entertainment,
in which adolescents who reported poorer self-control
relative to their peers also engaged in greater digital
technology use for entertainment. There was no robust
support for within-person associations. These findings
suggest that adolescents with poorer self-control may have
established tendencies to experience greater technological
impairment and use more digital technology for
entertainment, but the lack of within-person associations
indicate caution is needed for a cause-and-effect relation.
Adolescents with existing poorer self-control may be more
vulnerable to problematic digital technology use in a
developmental period where digital technology is
particularly rewarding, and intervention and prevention
efforts should be geared toward these adolescents. (PsycInfo
Database Record (c) 2023 APA, all rights
reserved).},
Doi = {10.1037/dev0001444},
Key = {fds367225}
}
@article{fds369351,
Author = {Andrade, FC and Hoyle, RH},
Title = {A synthesis and meta-analysis of the relationship between
trait self-control and healthier practices in physical
activity, eating, and sleep domains},
Journal = {Personality and Individual Differences},
Volume = {205},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1016/j.paid.2023.112095},
Abstract = {This paper updates and extends prior work by meta-analyzing
the fast-growing literature on the association between
individual differences in trait self-control and multiple
outcomes within the domains of physical activity, eating,
and sleep. Random-effects models with nesting by study and
sample were estimated for the aggregate association between
self-control and all health-related domains, for each domain
independently, and for moderated meta-regressions testing
whether effect sizes varied by method, measurement, and
sampling within each domain. Self-control was modestly
associated with engagement in health-related activities,
with significantly stronger associations for sleep relative
to eating and physical activity-related outcomes. Within
eating and sleep domains, associations significantly varied
as a function of outcome type and whether they were assessed
in terms of health-promotion or health-risk practices.
Findings suggest that the upper bound of what can be
predicted by individual differences in self-control varies
by health-related outcome. Importantly, smaller associations
point to the potential role of other individual differences,
contextual affordances, and biological factors in explaining
healthier physical activity, eating, and sleep-related
practices. The granular approach taken in this investigation
may ultimately aid the translation of a growing literature
on the role of individual differences in self-control into
effective health behavior maintenance and change
interventions.},
Doi = {10.1016/j.paid.2023.112095},
Key = {fds369351}
}
@article{fds369071,
Author = {Meyerson, WU and Fineberg, SK and Song, YK and Faber, A and Ash, G and Andrade, FC and Corlett, P and Gerstein, MB and Hoyle,
RH},
Title = {Estimation of Bedtimes of Reddit Users: Integrated Analysis
of Time Stamps and Surveys.},
Journal = {JMIR formative research},
Volume = {7},
Pages = {e38112},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.2196/38112},
Abstract = {<h4>Background</h4>Individuals with later bedtimes have an
increased risk of difficulties with mood and substances. To
investigate the causes and consequences of late bedtimes and
other sleep patterns, researchers are exploring social media
as a data source. Pioneering studies inferred sleep patterns
directly from social media data. While innovative, these
efforts are variously unscalable, context dependent,
confined to specific sleep parameters, or rest on untested
assumptions, and none of the reviewed studies apply to the
popular Reddit platform or release software to the research
community.<h4>Objective</h4>This study builds on this prior
work. We estimate the bedtimes of Reddit users from the
times tamps of their posts, test inference validity against
survey data, and release our model as an R package (The R
Foundation).<h4>Methods</h4>We included 159 sufficiently
active Reddit users with known time zones and known,
nonanomalous bedtimes, together with the time stamps of
their 2.1 million posts. The model's form was chosen by
visualizing the aggregate distribution of the timing of
users' posts relative to their reported bedtimes. The chosen
model represents a user's frequency of Reddit posting by
time of day, with a flat portion before bedtime and a
quadratic depletion that begins near the user's bedtime,
with parameters fitted to the data. This model estimates the
bedtimes of individual Reddit users from the time stamps of
their posts. Model performance is assessed through k-fold
cross-validation. We then apply the model to estimate the
bedtimes of 51,372 sufficiently active, nonbot Reddit users
with known time zones from the time stamps of their 140
million posts.<h4>Results</h4>The Pearson correlation
between expected and observed Reddit posting frequencies in
our model was 0.997 on aggregate data. On average, posting
starts declining 45 minutes before bedtime, reaches a nadir
4.75 hours after bedtime that is 87% lower than the daytime
rate, and returns to baseline 10.25 hours after bedtime. The
Pearson correlation between inferred and reported bedtimes
for individual users was 0.61 (P<.001). In 90 of 159 cases
(56.6%), our estimate was within 1 hour of the reported
bedtime; 128 cases (80.5%) were within 2 hours. There was
equivalent accuracy in hold-out sets versus training sets of
k-fold cross-validation, arguing against overfitting. The
model was more accurate than a random forest
approach.<h4>Conclusions</h4>We uncovered a simple,
reproducible relationship between Reddit users' reported
bedtimes and the time of day when high daytime posting rates
transition to low nighttime posting rates. We captured this
relationship in a model that estimates users' bedtimes from
the time stamps of their posts. Limitations include
applicability only to users who post frequently, the
requirement for time zone data, and limits on
generalizability. Nonetheless, it is a step forward for
inferring the sleep parameters of social media users
passively at scale. Our model and precomputed estimated
bedtimes of 50,000 Reddit users are freely
available.},
Doi = {10.2196/38112},
Key = {fds369071}
}
@article{fds369072,
Author = {Berntsen, D and Hoyle, RH and Munkholm Møller and D and Rubin,
DC},
Title = {Digital daydreaming: Introducing the spontaneous smartphone
checking scale},
Journal = {Applied Cognitive Psychology},
Volume = {37},
Number = {1},
Pages = {147-160},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1002/acp.4034},
Abstract = {Smartphones are a ubiquitous part of many people's lives,
but little is known about their impact on everyday thought
processes. Here we introduce the spontaneous smartphone
checking scale (SSCS)—which measures the tendency to
direct attention toward one's smartphone, unpreceded by
external prompts (e.g., notifications, or alerts) and with
no specific conscious goal in mind, as a parallel to
mind-wandering directed toward internal thoughts. The SSCS
showed good psychometric properties and construct validity.
It separated from measures of daydreaming and mind-wandering
by not loading on dimensions related to self-consciousness,
reflection, and rumination, but instead loading highly on a
factor associated with other aspects of digital
communication and concerns about public appearance on social
media. This suggests that spontaneous smartphone checking
serves different mental and social functions than internally
generated spontaneous thought processes. We discuss possible
long-term effects of spontaneous smartphone checking taking
up time for internally generated spontaneous
thoughts.},
Doi = {10.1002/acp.4034},
Key = {fds369072}
}
@article{fds372820,
Author = {Meyerson, WU and Hoyle, RH},
Title = {Pre-pandemic activity on a myalgic encephalomyelitis/chronic
fatigue syndrome support forum is highly associated with
later activity on a long COVID support forum for a variety
of reasons: A mixed methods study.},
Journal = {PloS one},
Volume = {18},
Number = {9},
Pages = {e0291173},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1371/journal.pone.0291173},
Abstract = {Encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long
COVID share some clinical and social characteristics. We
predicted that this would lead to an increased interaction
between pre-pandemic members of an ME/CFS online support
community and a long COVID community. We performed a
mixed-methods retrospective observational study of the
Reddit activity of 7,544 users active on Reddit's long COVID
forum. From among 1600 forums, pre-pandemic activity
specifically on a ME/CFS forum is the top predictor of later
participation on the long COVID forum versus an acute COVID
support forum. In the qualitative portion, motives for this
co-participation included seeking mutual support and dual
identification with both conditions. Some of this effect may
be explained by pre-existing ME/CFS possibly being a risk
factor for long COVID and/or SARS-CoV-2 infection being a
cause of ME/CFS relapse. The high rate of ME/CFS patients
seeking mutual support on a long COVID forum speaks to the
long-suffering experience of these patients not feeling
heard or respected, and the hope of some ME/CFS patients to
gain legitimacy through the public's growing recognition of
long COVID.},
Doi = {10.1371/journal.pone.0291173},
Key = {fds372820}
}
%% Huang, Shenyang
@article{fds375239,
Author = {Huang, S and Howard, CM and Hovhannisyan, M and Ritchey, M and Cabeza,
R and Davis, SW},
Title = {Hippocampal Functions Modulate Transfer-Appropriate Cortical
Representations Supporting Subsequent Memory.},
Journal = {J Neurosci},
Volume = {44},
Number = {1},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1523/JNEUROSCI.1135-23.2023},
Abstract = {The hippocampus plays a central role as a coordinate system
or index of information stored in neocortical loci.
Nonetheless, it remains unclear how hippocampal processes
integrate with cortical information to facilitate successful
memory encoding. Thus, the goal of the current study was to
identify specific hippocampal-cortical interactions that
support object encoding. We collected fMRI data while 19
human participants (7 female and 12 male) encoded images of
real-world objects and tested their memory for object
concepts and image exemplars (i.e., conceptual and
perceptual memory). Representational similarity analysis
revealed robust representations of visual and semantic
information in canonical visual (e.g., occipital cortex) and
semantic (e.g., angular gyrus) regions in the cortex, but
not in the hippocampus. Critically, hippocampal functions
modulated the mnemonic impact of cortical representations
that are most pertinent to future memory demands, or
transfer-appropriate representations Subsequent perceptual
memory was best predicted by the strength of visual
representations in ventromedial occipital cortex in
coordination with hippocampal activity and pattern
information during encoding. In parallel, subsequent
conceptual memory was best predicted by the strength of
semantic representations in left inferior frontal gyrus and
angular gyrus in coordination with either hippocampal
activity or semantic representational strength during
encoding. We found no evidence for transfer-incongruent
hippocampal-cortical interactions supporting subsequent
memory (i.e., no hippocampal interactions with cortical
visual/semantic representations supported
conceptual/perceptual memory). Collectively, these results
suggest that diverse hippocampal functions flexibly modulate
cortical representations of object properties to satisfy
distinct future memory demands.Significance Statement The
hippocampus is theorized to index pieces of information
stored throughout the cortex to support episodic memory. Yet
how hippocampal processes integrate with cortical
representation of stimulus information remains unclear.
Using fMRI, we examined various forms of
hippocampal-cortical interactions during object encoding in
relation to subsequent performance on conceptual and
perceptual memory tests. Our results revealed novel
hippocampal-cortical interactions that utilize semantic and
visual representations in transfer-appropriate manners:
conceptual memory supported by hippocampal modulation of
frontoparietal semantic representations, and perceptual
memory supported by hippocampal modulation of occipital
visual representations. These findings provide important
insights into the neural mechanisms underlying the formation
of information-rich episodic memory and underscore the value
of studying the flexible interplay between brain regions for
complex cognition.},
Doi = {10.1523/JNEUROSCI.1135-23.2023},
Key = {fds375239}
}
@article{fds375862,
Author = {Huang, S and Paul, U and Gupta, S and Desai, K and Guo, M and Jung, J and Capestany, B and Krenzer, WD and Stonecipher, D and Farahany,
N},
Title = {U.S. public perceptions of the sensitivity of brain
data.},
Journal = {Journal of law and the biosciences},
Volume = {11},
Number = {1},
Pages = {lsad032},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1093/jlb/lsad032},
Abstract = {As we approach an era of potentially widespread consumer
neurotechnology, scholars and organizations worldwide have
started to raise concerns about the data privacy issues
these devices will present. Notably absent in these
discussions is empirical evidence about how the public
perceives that same information. This article presents the
results of a nationwide survey on public perceptions of
brain data, to inform discussions of law and policy
regarding brain data governance. The survey reveals that the
public may perceive certain brain data as less sensitive
than other 'private' information, like social security
numbers, but more sensitive than some 'public' information,
like media preferences. The findings also reveal that not
all inferences about mental experiences may be perceived as
equally sensitive, and perhaps not all data should be
treated alike in ethical and policy discussions. An enhanced
understanding of public perceptions of brain data could
advance the development of ethical and legal norms
concerning consumer neurotechnology.},
Doi = {10.1093/jlb/lsad032},
Key = {fds375862}
}
@article{fds372738,
Author = {Stanley, ML and Huang, S and Marsh, EJ and Kay, AC},
Title = {The Role of Structure-Seeking in Moral Punishment},
Journal = {Social Justice Research},
Volume = {36},
Number = {4},
Pages = {410-431},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1007/s11211-023-00416-8},
Abstract = {Four studies (total N = 1586) test the notion that people
are motivated to punish moral rule violators because
punishment offers a way to obtain structure and order in the
world. First, in a correlational study, increased need for
structure was associated with the stronger endorsement
punishment for moral rule violators. This relationship
between need for structure and punishment was not driven by
political conservatism. Three experimental studies then
tested, and corroborated, our main causal hypotheses: that
threats to structure increase punitive judgments for moral
rule violators (i.e., a compensatory mechanism; Study 2) and
that a lack of punishment for wrongdoing (relative to
punishment for wrongdoing) makes the world seem less
structured in the moment (Studies 3 and 4). We compare and
contrast our structure-based account of moral punishment to
other theories and findings across the punishment
literature.},
Doi = {10.1007/s11211-023-00416-8},
Key = {fds372738}
}
%% Johnson, Savannah
@article{fds376093,
Author = {Johnson, SL and Mootz, J and Waller, B and Fortunato Dos Santos and P and Jaguga, F and Giusto, A},
Title = {A global call for adolescent intimate partner violence
prevention.},
Journal = {The lancet. Psychiatry},
Volume = {11},
Number = {4},
Pages = {238-239},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1016/s2215-0366(23)00435-2},
Doi = {10.1016/s2215-0366(23)00435-2},
Key = {fds376093}
}
@article{fds376692,
Author = {Johnson, SL and Rieder, AD and Rasmussen, JM and Mansoor, M and Quick,
KN and Proeschold-Bell, RJ and Coping Together Team, and Boone, WJ and Puffer, ES},
Title = {A Pilot Study of the Coping Together Virtual Family
Intervention: Exploring Changes in Family Functioning and
Individual Well-Being.},
Journal = {Research on child and adolescent psychopathology},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1007/s10802-024-01183-z},
Abstract = {In this pilot study, we tested a virtual family
strengthening and mental health promotion intervention,
Coping Together (CT), during the COVID-19 pandemic. We
explored changes at the family and individual levels, as
well as mechanisms of change. Participants included 18
families (24 caregivers, 24 youth) with children aged 7 to
18 years. Community health workers delivered the 8-session
CT intervention using videoconferencing software. We used
qualitative semi-structured interviews with 14 of the
families to explore changes and mechanisms of change using a
thematic content analysis approach. We also administered
pre-post surveys with the 18 families to explore the
direction of changes, using only descriptive statistics in
this small sample. Qualitative findings supported positive
changes across family and individual level outcomes
including family functioning, relationship quality, and
individual psychosocial well-being. Results also confirmed
several hypothesized mechanisms of change with improved
communication providing the foundation for increased hope
and improved problem solving and coping. Pre-post survey
results were mixed, showing positive, but very small,
changes in family closeness, caregiver-child communication,
and levels of hope; almost no change was observed on
measures of caregiver and child mental health. Families
reported few problems at baseline quantitatively despite
qualitative descriptions of pre-intervention difficulties.
Results provide preliminary support for benefits of CT with
the most consistent improvements seen across family
relationships. Findings were mixed related to
individual-level mental health benefits. Results have
implications for revising content on mental health coping
strategies and suggest the need to revise the quantitative
measurement strategy for this non-clinical
sample.},
Doi = {10.1007/s10802-024-01183-z},
Key = {fds376692}
}
@article{fds373509,
Author = {Johnson, S and Quick, KN and Rieder, AD and Rasmussen, JD and Sanyal, A and Green, EP and Duerr, E and Nagy, GA and Puffer, ES},
Title = {Social Vulnerability, COVID-19, Racial Violence, and
Depressive Symptoms: a Cross-sectional Study in the Southern
United States.},
Journal = {Journal of racial and ethnic health disparities},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1007/s40615-023-01831-y},
Abstract = {<h4>Background</h4>In March 2020, the novel 2019 coronavirus
disease (COVID-19) was declared a pandemic. In May 2020,
George Floyd was murdered, catalyzing a national racial
reckoning. In the Southern United States, these events
occurred in the context of a history of racism and high
rates of poverty and discrimination, especially among
racially and ethnically minoritized populations.<h4>Objectives</h4>In
this study, we examine social vulnerabilities, the perceived
impacts of COVID-19 and the national racial reckoning, and
how these are associated with depression symptoms in the
South.<h4>Methods</h4>Data were collected from 961 adults
between June and November 2020 as part of an online survey
study on family well-being during COVID-19. The sample was
majority female (87.2%) and consisted of 661 White
participants, 143 Black participants, and 157 other racial
and ethnic minoritized participants. Existing social
vulnerability, perceived impact of COVID-19 and racial
violence and protests on families, and depressive symptoms
were assessed. Hierarchical regression analysis was used to
predict variance in depressive symptoms.<h4>Results</h4>Half
of the sample (52%) reported a negative impact of COVID-19,
and 66% reported a negative impact of national racial
violence/protests. Depressive symptoms were common with
49.8% meeting the cutoff for significant depressive
symptoms; Black participants had lower levels of depressive
symptoms. Results from the hierarchical regression analysis
indicate social vulnerabilities and the perceived negative
impact of COVID-19 and racial violence/protests each
contribute to variance in depressive symptoms. Race-specific
sensitivity analysis clarified distinct patterns in
predictors of depressive symptoms.<h4>Conclusion</h4>People
in the South report being negatively impacted by the
confluence of the COVID-19 pandemic and the emergence of
racial violence/protests in 2020, though patterns differ by
racial group. These events, on top of pre-existing social
vulnerabilities, help explain depressive symptoms in the
South during 2020.},
Doi = {10.1007/s40615-023-01831-y},
Key = {fds373509}
}
%% Katz, Trisha
@article{fds372786,
Author = {Katz, T and Kushnir, T and Tomasello, M},
Title = {Children are eager to take credit for prosocial acts, and
cost affects this tendency.},
Journal = {Journal of experimental child psychology},
Volume = {237},
Pages = {105764},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.jecp.2023.105764},
Abstract = {We report two experiments on children's tendency to enhance
their reputations through communicative acts. In the
experiments, 4-year-olds (N = 120) had the opportunity to
inform a social partner that they had helped him in his
absence. In a first experiment, we pitted a prosocial act
("Let's help clean up for Doggie!") against an instrumental
act ("Let's move these out of our way"). Children in the
prosocial condition were quicker to inform their partner of
the act and more likely to protest when another individual
was given credit for it. In a second experiment, we
replicated the prosocial condition but with a new
manipulation: high-cost versus low-cost helping. We
manipulated both the language surrounding cost (i.e., "This
will be pretty tough to clean up" vs. "It will be really
easy to clean this up") and how difficult the task itself
was. As predicted, children in the high-cost condition were
quicker to inform their partner of the act and more likely
to take back credit for it. These results suggest that even
4-year-old children make active attempts to elicit positive
reputational judgments for their prosocial acts, with cost
as a moderating factor.},
Doi = {10.1016/j.jecp.2023.105764},
Key = {fds372786}
}
%% Kay, Aaron C.
@article{fds371676,
Author = {Stanley, ML and Huang, S and Marsh, EJ and Kay, AC},
Title = {The Role of Structure-Seeking in Moral Punishment},
Journal = {Social Justice Research},
Volume = {36},
Number = {4},
Pages = {410-431},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1007/s11211-023-00416-8},
Abstract = {Four studies (total N = 1586) test the notion that people
are motivated to punish moral rule violators because
punishment offers a way to obtain structure and order in the
world. First, in a correlational study, increased need for
structure was associated with the stronger endorsement
punishment for moral rule violators. This relationship
between need for structure and punishment was not driven by
political conservatism. Three experimental studies then
tested, and corroborated, our main causal hypotheses: that
threats to structure increase punitive judgments for moral
rule violators (i.e., a compensatory mechanism; Study 2) and
that a lack of punishment for wrongdoing (relative to
punishment for wrongdoing) makes the world seem less
structured in the moment (Studies 3 and 4). We compare and
contrast our structure-based account of moral punishment to
other theories and findings across the punishment
literature.},
Doi = {10.1007/s11211-023-00416-8},
Key = {fds371676}
}
@article{fds373580,
Author = {Tang, S and Shepherd, S and Kay, AC},
Title = {Morality's role in the Black Sheep Effect: When and why
ingroup members are judged more harshly than outgroup
members for the same transgression},
Journal = {European Journal of Social Psychology},
Volume = {53},
Number = {7},
Pages = {1605-1622},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1002/ejsp.3001},
Abstract = {When and why might someone judge an ingroup transgressor
more harshly than an outgroup transgressor? Taking a social
functionalist perspective, we argue that morality is central
to this phenomenon–the Black Sheep Effect–and that it is
driven by social cohesion concerns. Using mediation and
moderation methods across our studies, we find that people
judge ingroup (vs. outgroup) transgressors more harshly
because of concerns regarding ingroup social cohesion
(Studies 1a–4). We also find that ingroup derogation is
stronger for moral transgressions than weak or non-moral
transgressions (Studies 2 and 3). Throughout our studies, we
address alternative explanations, including moral
relativism, naïve realism, moral parochialism and belief in
a just world. Our work speaks to the emerging contention
around the reliability of the Black Sheep Effect by noting
when and why it surfaces.},
Doi = {10.1002/ejsp.3001},
Key = {fds373580}
}
@article{fds370748,
Author = {Kay, AC and Ponce de Leon and R and Ho, AK and Kteily,
NS},
Title = {Motivated Egalitarianism},
Journal = {Current Directions in Psychological Science},
Volume = {32},
Number = {4},
Pages = {293-299},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1177/09637214231154810},
Abstract = {Much research has examined the link between
(anti-)egalitarian ideology and motivated social cognition.
However, this research is typically framed around
anti-egalitarianism, with the other end of this ideological
pole, egalitarianism, often ignored altogether or treated as
merely the absence of anti-egalitarian-motivated cognition.
We integrate long-standing ideas from social dominance
theory with contemporary models of motivated social
cognition and a recent wave of empirical findings to argue
that egalitarian ideology also drives social cognition in
meaningful ways. We discuss why pursuing this avenue of
research is important and outline several unanswered
questions for future research.},
Doi = {10.1177/09637214231154810},
Key = {fds370748}
}
@article{fds370323,
Author = {Stanley, ML and Shepherd, S and Kay, AC},
Title = {Heroization and ironic funneling effects.},
Journal = {Journal of personality and social psychology},
Volume = {125},
Number = {1},
Pages = {29-56},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1037/pspa0000336},
Abstract = {In recent years, much of the American public has venerated
military veterans as heroes. Despite overwhelmingly positive
public attitudes toward veterans, veterans have experienced
higher rates of unemployment and underemployment than their
nonveteran peers. The current research leverages theory and
research on positive stereotypes to shed light on this
seeming inconsistency between the heroization of veterans
and their heightened rates of unemployment and
underemployment. We conceptualize the hero label as a
pervasive positive stereotype, and we employ complementary
methods and designs (correlational, quasi-experimental,
experimental, and mediational) to investigate the
consequences and implications of attaching this label to
military veterans. We then extend our theorizing to other
heroized groups (e.g., firefighters, paramedics, teachers,
and social workers). The results across studies suggest that
heroization leads the American public to funnel heroized
individuals and groups into a limited set of lower paying
jobs, organizations, and careers associated with
selflessness. This research not only offers insights into an
important real-world problem but also offers a first
experimental investigation of the consequences and
implications of labeling a group of people as heroes.
(PsycInfo Database Record (c) 2023 APA, all rights
reserved).},
Doi = {10.1037/pspa0000336},
Key = {fds370323}
}
@article{fds376863,
Author = {Jost, JT and Goya-Tocchetto, D and Kay, AC},
Title = {The Psychology of Left-Right Political Polarization; and an
Experimental Intervention for Curbing Partisan Animosity and
Support for Antidemocratic Violence},
Journal = {Annals of the American Academy of Political and Social
Science},
Volume = {708},
Number = {1},
Pages = {46-63},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1177/00027162241227778},
Abstract = {Healthy democratic polities feature competing visions of a
good society. They also require tolerance, trust, and
cooperation to avoid toxic polarization that puts democracy
itself at risk. In the U.S., liberal-leftists and
conservative-rightists differ in many attitudes, values, and
personality traits, as well as tendencies to justify the
unequal status quo and embrace authoritarian aggression and
group-based dominance. Some of these differences imply that
conflict between liberal-leftists and conservative-rightists
is tantamount to a struggle for and against democratic
ideals. However, these political and psychological
differences between the left and the right do not
necessarily mean that Americans are forever doomed to
intergroup hatred and intractable political conflict. Some
modest basis for optimism emerges from recent experimental
interventions, including one that encourages people to
identify with and justify the system of liberal democracy in
the U.S.},
Doi = {10.1177/00027162241227778},
Key = {fds376863}
}
@article{fds367908,
Author = {Ma, A and Savani, K and Liu, F and Tai, K and Kay, AC},
Title = {The mutual constitution of culture and psyche: The
bidirectional relationship between individuals' perceived
control and cultural tightness-looseness.},
Journal = {Journal of personality and social psychology},
Volume = {124},
Number = {5},
Pages = {901-916},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1037/pspa0000327},
Abstract = {According to the theory of mutual constitution of culture
and psyche, just as culture shapes people, individuals'
psychological states can influence culture. We build on
compensatory control theory, which suggests that low
personal control can lead people to prefer societal systems
that impose order, to examine the mutual constitution of
personal control and cultural tightness. Specifically, we
tested whether individuals' lack of personal control
increases their preference for tighter cultures as a means
of restoring order and predictability, and whether tighter
cultures in turn reduce people's feelings of personal
control. Seven studies (five preregistered) with
participants from the United States, Singapore, and China
examine this cycle of mutual constitution. Specifically,
documenting the correlational link between person and
culture, we found that Americans lower on personal control
preferred to live in tighter states (Study 1). Chinese
employees lower on personal control also desired more
structure and preferred a tighter organizational culture
(Study 2). Employing an experimental causal chain design,
Studies 3-5 provided causal evidence for our claim that lack
of control increases desire for tighter cultures via the
need for structure. Finally, tracing the link back from
culture to person, Studies 6a and 6b found that whereas
tighter cultures decreased perceptions of individual
personal control, they increased people's sense of
collective control. Overall, the findings document the
process of mutual constitution of culture and psyche: lack
of personal control leads people to seek more structured,
tighter cultures, and that tighter cultures, in turn,
decrease people's sense of personal control but increase
their sense of collective control. (PsycInfo Database Record
(c) 2023 APA, all rights reserved).},
Doi = {10.1037/pspa0000327},
Key = {fds367908}
}
@article{fds368557,
Author = {Gibbs, WC and Kim, HS and Kay, AC and Sherman, DK},
Title = {Who needs control? A cultural perspective on the process of
compensatory control},
Journal = {Social and Personality Psychology Compass},
Volume = {17},
Number = {2},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1111/spc3.12722},
Abstract = {Compensatory control theory (CCT) provides a framework for
understanding the mechanisms at play when one's personal
control is challenged. The model suggests that believing the
world is a structured and predictable place is fundamental,
insofar as it provides the foundation upon which people can
believe they are able to exert control over their
environment and act agentically towards goals. Because of
this, CCT suggests, when personal control is threatened
people try to reaffirm the more foundational belief in
structure/predictability in the world, so that they then
have a strong foundation to reestablish feelings of personal
control and pursue their goals. This review seeks to
understand how the basic assumptions of these compensatory
control processes unfold in different cultural contexts.
Drawing on research and theorizing from cultural psychology,
we propose that cultural models of self and agency,
culturally prevalent modes of control, and culture-specific
motivations all have implications for compensatory control
processes. Culture determines, in part, whether or not
personal control deprivation is experienced as a threat to
perceiving an orderly world, how/whether individuals respond
to low personal control, and the function that responses to
restore a sense of order in the world serve. A theoretical
model of compensatory control processes across cultures is
proposed that has implications for how people cope with a
wide range of personal and societal events that potentially
threaten their personal control.},
Doi = {10.1111/spc3.12722},
Key = {fds368557}
}
@article{fds371526,
Author = {Kenthirarajah, DT and Camp, NP and Walton, GM and Kay, AC and Cohen,
GL},
Title = {Does "Jamal" receive a harsher sentence than "James"?
First-name bias in the criminal sentencing of Black
men.},
Journal = {Law and human behavior},
Volume = {47},
Number = {1},
Pages = {169-181},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1037/lhb0000498},
Abstract = {<h4>Objective</h4>Using archival and experimental methods,
we tested the role that racial associations of first names
play in criminal sentencing.<h4>Hypotheses</h4>We
hypothesized that Black defendants with more stereotypically
Black names (e.g., Jamal) would receive more punitive
sentences than Black defendants with more stereotypically
White names (e.g., James).<h4>Method</h4>In an archival
study, we obtained a random sample of 296 real-world records
of Black male prison inmates in Florida and asked
participants to rate the extent to which each inmate's first
name was stereotypically Black or stereotypically White. We
then tested the extent to which racial stereotypicality was
associated with sentence length, controlling for relevant
legal features of each case (e.g., criminal record, severity
of convicted offenses). In a follow-up experiment,
participant judges assigned sentences in cases in which the
Black male defendant was randomly assigned a more
stereotypically Black or White name from our archival
study.<h4>Results</h4>Controlling for a wide array of
factors-including criminal record-we found that inmates with
more stereotypically Black versus White first names received
longer sentences β = 0.09, 95% confidence interval (95% CI)
[0.01, 0.16]: 409 days longer for names 1 standard deviation
above versus below the mean on racial stereotypicality. In
our experiment, participant judges recommended significantly
longer sentences to Black inmates with more stereotypically
Black names above and beyond the severity of the charges or
their criminal history, β = 0.07, 95% CI [0.02,
0.13].<h4>Conclusions</h4>Our results identify how racial
associations with first names can bias consequential
sentencing decisions despite the impartial aims of the legal
system. More broadly, our findings illustrate how racial
biases manifest in distinctions made among members of
historically marginalized groups, not just between members
of different groups. (PsycInfo Database Record (c) 2023 APA,
all rights reserved).},
Doi = {10.1037/lhb0000498},
Key = {fds371526}
}
@article{fds363672,
Author = {Proudfoot, D and Kay, AC},
Title = {Communal expectations conflict with autonomy motives: The
western drive for autonomy shapes women's negative responses
to positive gender stereotypes.},
Journal = {Journal of personality and social psychology},
Volume = {124},
Number = {1},
Pages = {1-21},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1037/pspa0000311},
Abstract = {Western culture idealizes an autonomous self-a self that
strives for independence and freedom from the influence and
control of others. We explored how the value placed on
autonomy in Western culture intersects with the normative
trait expectations experienced by men and women. While trait
expectations placed on men (i.e., to be confident and
assertive) affirm an autonomous sense of self, trait
expectations placed on women (i.e., to be caring and
understanding) conflict with an autonomous sense of self. We
theorized that this conflict contributes to women's
resentment toward positive gender stereotypes that emphasize
women's interdependent qualities. Six preregistered studies
(<i>N</i> = 2,094) demonstrated that U.S. women experienced
more anger in response to positive-gendered trait
expectations and less motivation to comply with them
compared to U.S. men. We found that these effects were
partially attributable to stereotypically feminine communal
expectations affirming autonomy less than stereotypically
masculine agentic expectations. Cross-cultural comparisons
between the U.S. (a Western context) and India (a
non-Western context) further indicated that the conflict
between communal expectations placed on women and Western
prioritization of autonomy contributes to U.S. women's anger
toward positive gender stereotypes: Although traits expected
of women in both the U.S. and India oriented women away from
feeling autonomous more than traits expected of men, this
diminished sense of being autonomous only elicited anger in
a U.S. context. For Western societies, findings illuminate
the uniquely frustrating nature of stereotyped expectations
that demand interdependence and thus the unequal
psychological burden placed on those who must contend with
them. (PsycInfo Database Record (c) 2022 APA, all rights
reserved).},
Doi = {10.1037/pspa0000311},
Key = {fds363672}
}
%% Keefe, Francis J.
@article{fds376035,
Author = {Hooker, JE and Brewer, JR and McDermott, KA and Kanaya, M and Somers,
TJ and Keefe, F and Kelleher, S and Fisher, HM and Burns, J and Jeddi, RW and Kulich, R and Polykoff, G and Parker, RA and THRIVE Study Team, and Greenberg, J and Vranceanu, A-M},
Title = {Improving multimodal physical function in adults with
heterogeneous chronic pain; Protocol for a multisite
feasibility RCT.},
Journal = {Contemp Clin Trials},
Volume = {138},
Pages = {107462},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1016/j.cct.2024.107462},
Abstract = {BACKGROUND: Chronic pain is associated with substantial
impairment in physical function, which has been identified
as a top concern among persons with pain. GetActive-Fitbit,
a mind-body activity program, is feasible, acceptable, and
associated with improvement in physical function among
primarily White, sedentary individuals with pain. In
preparation for a multisite efficacy trial, we must examine
feasibility across multiple sites with diverse patient
populations. Here we describe the protocol of a multisite,
feasibility RCT comparing GetActive-Fitbit with a time- and
attention-matched educational comparison (Healthy Living for
Pain). We aim to 1) test multisite fidelity of clinician
training; 2) evaluate multisite feasibility benchmarks,
including recruitment of chronic pain patients taking <5000
steps/day and racial and ethnic minorities; and 3) optimize
fidelity and study protocol in preparation for a future
multisite efficacy trial. METHODS: Clinician training
fidelity was assessed via roleplays and mock group sessions.
Feasibility (i.e., recruitment, acceptability, credibility,
adherence, satisfaction), multimodal physical function
(e.g., self-report, 6-Minute Walk Test, step-count), and
other psychosocial outcomes are assessed at baseline,
posttest, and 6 months. Protocol optimization will be
assessed using exit interviews and cross-site meetings.
RESULTS: The trial is ongoing. Clinician training is
complete. 87 participants have been recruited. 54 completed
baseline assessments and randomization, 44 are
mid-intervention, and 9 have completed the intervention and
posttest. CONCLUSIONS: This study addresses the critical
need for feasible, acceptable mind-body-activity
interventions for chronic pain that follow evidence-based
guidelines and improve all aspects of physical function
across diverse populations. Results will inform a future
fully-powered multisite efficacy trial. CLINICAL TRIAL
REGISTRATION: NCT05700383.},
Doi = {10.1016/j.cct.2024.107462},
Key = {fds376035}
}
@article{fds376779,
Author = {Beneciuk, JM and George, SZ and Simon, CB and Ballengee, LA and Lentz,
TA and Greco, CM and Main, CJ and Keefe, FJ},
Title = {On "Fragility and Back Pain: Lessons From the Frontiers of
Biopsychosocial Practice." Nicholls DA. Phys Ther. 2023;
103:pzad040. https://doi.org/10.1093/ptj/pzad040.},
Journal = {Phys Ther},
Volume = {104},
Number = {3},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1093/ptj/pzae002},
Doi = {10.1093/ptj/pzae002},
Key = {fds376779}
}
@article{fds376780,
Author = {Keefe, FJ and Winger, JG and Kelleher, SA},
Title = {Pain-related suffering: new insights into what it means and
new opportunities for research and clinical
practice.},
Journal = {Pain},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1097/j.pain.0000000000003196},
Doi = {10.1097/j.pain.0000000000003196},
Key = {fds376780}
}
@article{fds373556,
Author = {Cook, CE and O'Halloran, B and McDevitt, A and Keefe,
FJ},
Title = {Specific and shared mechanisms associated with treatment for
chronic neck pain: study protocol for the SS-MECH
trial.},
Journal = {J Man Manip Ther},
Volume = {32},
Number = {1},
Pages = {85-95},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1080/10669817.2023.2267391},
Abstract = {BACKGROUND: Treatment mechanisms involve the steps or
processes through which an intervention unfolds and produces
change in an outcome variable. Treatment mechanisms can be
specific to the intervention provided (i.e. pain modulation)
or shared with other treatments (i.e. reduced fear of
movement). Whether specific and shared treatment mechanisms
are different across interventions and whether they lead to
the outcomes seen in trials is largely unknown. The
management of individuals with chronic neck pain routinely
include manual therapy (MT) and resistance exercise (RE), as
both approaches are included in clinical practice guidelines
and both yield similar outcomes. OBJECTIVES: Our study plans
to answer two research questions: 1) what are the specific
mechanisms associated with MT versus interventions (and are
these different), and 2) what are the shared mechanisms
associated with these interventions, and do specific or
shared mechanisms mediate clinical outcomes? METHODS: This
study will involve a 2-group parallel (1:1) single-blinded
randomized trial to compare the specific and potential
shared treatment mechanisms between these two approaches. We
will enroll individuals with a history of chronic neck pain
and evaluate whether specific or shared mechanisms mediate
clinical outcomes. RESULTS: We hypothesize that MT and RE
approaches will both exhibit different specific treatment
mechanisms, and that both approaches will exhibit shared
treatment mechanisms, which will notably influence outcomes
at both discharge and 6-months. CONCLUSIONS: This study is
important because it will help identify what specific or
shared treatment mechanisms are associated with different
interventions and, how different treatment mechanisms
influence clinical outcomes.},
Doi = {10.1080/10669817.2023.2267391},
Key = {fds373556}
}
@article{fds376088,
Author = {Burns, JW and Jensen, MP and Thorn, BE and Lillis, TA and Carmody, J and Gerhart, J and Keefe, F},
Title = {Cognitive Therapy, Mindfulness-Based Stress Reduction, and
Behavior Therapy for the Treatment of Chronic Pain:
Predictors and Moderators of Treatment Response.},
Journal = {J Pain},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.jpain.2024.01.003},
Abstract = {Psychosocial interventions for people with chronic pain
produce significant improvements in outcomes, but these
effects on average are modest with much variability in the
benefits conferred on individuals. To enhance the magnitude
of treatment effects, characteristics of people that might
predict the degree to which they respond more or less well
could be identified. People with chronic low back pain
(N = 521) participated in a randomized controlled trial
which compared cognitive therapy, mindfulness-based stress
reduction, behavior therapy and treatment as usual.
Hypotheses regarding predictors and/or moderators were based
on the Limit, Activate, and Enhance model; developed to
predict and explain moderators/predictors of psychosocial
pain treatments. Results were: 1) low levels of
cognitive/behavioral function at pre-treatment predicted
favorable pre- to post-treatment outcomes; 2) favorable
expectations of benefit from treatment and sound working
alliances predicted favorable pre- to post-treatment
outcomes; 3) women benefited more than men. These effects
emerged without regard to treatment condition. Of note, high
levels of cognitive/behavioral function at pre-treatment
predicted favorable outcomes only for people in the
treatment as usual condition. Analyses identified a set of
psychosocial variables that may act as treatment predictors
across cognitive therapy, mindfulness-based stress reduction
and behavior therapy, as hypothesized by the Limit,
Activate, and Enhance model if these 3 treatments operate
via similar mechanisms. Findings point toward people who may
and who may not benefit fully from the 3 psychosocial
treatments studied here, and so may guide future research on
matching people to these kinds of psychosocial approaches or
to other (eg, forced-based interventions) non-psychosocial
approaches. TRIAL REGISTRATION: The ClinicalTrials.gov
Identifier is NCT02133976. PERSPECTIVE: This article
examines potential predictors/moderators of response to
psychosocial treatments for chronic pain. Results could
guide efforts to match people to the most effective
treatment type or kind.},
Doi = {10.1016/j.jpain.2024.01.003},
Key = {fds376088}
}
@article{fds372549,
Author = {LaRowe, LR and Miaskowski, C and Miller, A and Mayfield, A and Keefe,
FJ and Smith, AK and Cooper, BA and Wei, L-J and Ritchie,
CS},
Title = {Chronic Pain and Pain Management in Older Adults: Protocol
and Pilot Results.},
Journal = {Nurs Res},
Volume = {73},
Number = {1},
Pages = {81-88},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1097/NNR.0000000000000683},
Abstract = {BACKGROUND: Chronic pain occurs in 30% of older adults. This
prevalence rate is expected to increase, given the growth in
the older adult population and the associated growth of
chronic conditions contributing to pain. No population-based
studies have provided detailed, longitudinal information on
the experience of chronic pain in older adults; the
pharmacological and nonpharmacological strategies that older
adults use to manage their chronic pain; and the effect of
chronic pain on patient-reported outcomes. OBJECTIVES: This
article aims to describe the protocol for a
population-based, longitudinal study focused on
understanding the experience of chronic pain in older
adults. The objectives are to determine the prevalence and
characteristics of chronic pain; identify the
pharmacological and nonpharmacological pain treatments used;
evaluate for longitudinal differences in biopsychosocial
factors; and examine how pain types and pain trajectories
affect important patient-reported outcomes. Also included
are the results of a pilot study. METHODS: A
population-based sample of approximately 1,888 older adults
will be recruited from the National Opinion Research Center
at the University of Chicago's AmeriSpeak Panel to complete
surveys at three waves: enrollment (Wave 1), 6 months (Wave
2), and 12 months (Wave 3). To determine the feasibility, a
pilot test of the enrollment survey was conducted among 123
older adults. RESULTS: In the pilot study, older adults with
chronic pain reported a range of pain conditions, with
osteoarthritis being the most common. Participants reported
an array of pharmacological and nonpharmacological pain
strategies. Compared to participants without chronic pain,
those with chronic pain reported lower physical and
cognitive function and poorer quality of life. Data
collection for the primary, longitudinal study is ongoing.
DISCUSSION: This project will be the first longitudinal
population-based study to examine the experience and overall
effect of chronic pain in older adults. Pilot study results
provide evidence of the feasibility of study methods.
Ultimately, this work will inform the development of
tailored interventions for older patients targeted to
decrease pain and improve function and quality of
life.},
Doi = {10.1097/NNR.0000000000000683},
Key = {fds372549}
}
@article{fds372966,
Author = {Kenney, MO and Wilson, S and Shah, N and Bortsov, A and Smith, WR and Little, J and Lanzkron, S and Kanter, J and Padrino, S and Owusu-Ansah,
A and Cohen, A and Desai, P and Manwani, D and Rehman, SSU and Hagar, W and Keefe, F},
Title = {Biopsychosocial Factors Associated With Pain and
Pain-Related Outcomes in Adults and Children With Sickle
Cell Disease: A Multivariable Analysis of the GRNDaD
Multicenter Registry.},
Journal = {J Pain},
Volume = {25},
Number = {1},
Pages = {153-164},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.jpain.2023.07.029},
Abstract = {Pain is the primary symptomatic manifestation of sickle cell
disease (SCD), an inherited hemoglobinopathy. The
characteristics that influence pain experiences and outcomes
in SCD are not fully understood. The primary objective of
this study was to use multivariable modeling to examine
associations of biopsychosocial variables with a
disease-specific measure of pain interference known as pain
impact. We conducted a secondary analysis of data from the
Global Research Network for Data and Discovery national SCD
registry. A total of 657 children and adults with SCD were
included in the analysis. This sample was 60% female with a
median age of 34 (interquartile range 26-42 years) and a
chronic pain prevalence of 64%. The model accounted for 58%
of the variance in pain impact. Low social (P < .001) and
emotional (P < .001) functioning, increasing age
(P = .004), low income (P < .001), and high acute
painful episodes (P = .007) were most strongly associated
with high pain impact in our multivariable model.
Additionally, multivariable modeling of pain severity and
physical function in 2 comparable samples of registry
participants revealed that increasing age and low social
functioning were also strongly associated with higher pain
severity and low physical functioning. Overall, the results
suggest that social and emotional functioning are more
strongly associated with pain impact in individuals with SCD
than previously studied biological modifiers such as SCD
genotype, hemoglobin, and percentage fetal hemoglobin.
Future research using longitudinally collected data is
needed to confirm these findings. PERSPECTIVE: This study
reveals that psychosocial (ie, social and emotional
functioning) and demographic (ie, age) variables may play an
important role in predicting pain and pain-related outcomes
in SCD. Our findings can inform future multicenter
prospective longitudinal studies aimed at identifying
modifiable psychosocial predictors of adverse pain outcomes
in SCD.},
Doi = {10.1016/j.jpain.2023.07.029},
Key = {fds372966}
}
@article{fds375365,
Author = {Dember, LM and Hsu, JY and Bernardo, L and Cavanaugh, KL and Charytan,
DM and Crowley, ST and Cukor, D and Doorenbos, AZ and Edwards, DA and Esserman, D and Fischer, MJ and Jhamb, M and Joffe, S and Johansen, KL and Kalim, S and Keefe, FJ and Kimmel, PL and Krebs, EE and Kuzla, N and Mehrotra, R and Mishra, P and Pellegrino, B and Steel, JL and Unruh, ML and White, DM and Yabes, JG and Becker, WC and HOPE Consortium},
Title = {The design and baseline characteristics for the HOPE
Consortium Trial to reduce pain and opioid use in
hemodialysis.},
Journal = {Contemp Clin Trials},
Volume = {136},
Pages = {107409},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.cct.2023.107409},
Abstract = {The HOPE Consortium Trial to Reduce Pain and Opioid Use in
Hemodialysis (HOPE Trial) is a multicenter randomized trial
addressing chronic pain among patients receiving maintenance
hemodialysis for end-stage kidney disease. The trial uses a
sequential, multiple assignment design with a randomized
component for all participants (Phase 1) and a
non-randomized component for a subset of participants (Phase
2). During Phase 1, participants are randomized to Pain
Coping Skills Training (PCST), an intervention designed to
increase self-efficacy for managing pain, or Usual Care.
PCST consists of weekly, live, coach-led cognitive
behavioral therapy sessions delivered by video- or
tele-conferencing for 12 weeks followed by daily
interactive voice response sessions delivered by telephone
for an additional 12 weeks. At 24 weeks (Phase 2),
participants in both the PCST and Usual Care groups taking
prescription opioid medications at an average dose of ≥20
morphine milligram equivalents per day are offered
buprenorphine, a partial opioid agonist with a more
favorable safety profile than full-agonist opioids. All
participants are followed for 36 weeks. The primary outcome
is pain interference ascertained, for the primary analysis,
at 12 weeks. Secondary outcomes include additional
patient-reported measures and clinical outcomes including
falls, hospitalizations, and death. Exploratory outcomes
include acceptability, tolerability, and efficacy of
buprenorphine. The enrollment target of 640 participants was
met 27 months after trial initiation. The findings of the
trial will inform the management of chronic pain, a common
and challenging issue for patients treated with maintenance
hemodialysis. NCT04571619.},
Doi = {10.1016/j.cct.2023.107409},
Key = {fds375365}
}
@article{fds373557,
Author = {Fisher, HM and Check, DK and Somers, TJ and Kelleher, SA and Majestic,
C and Yu, JA and Reed, SD and Li, Y and Olsen, MK and Lerebours, R and Keefe,
FJ and Steinhauser, KE and Breitbart, WS and Winger,
JG},
Title = {Meaning-centered pain coping skills training for patients
with metastatic cancer: Protocol for a randomized controlled
efficacy trial.},
Journal = {Contemp Clin Trials},
Volume = {135},
Pages = {107363},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1016/j.cct.2023.107363},
Abstract = {BACKGROUND: Many patients with advanced cancer describe pain
as a debilitating symptom that greatly interferes with daily
activities and enjoyment of life. Psychosocial interventions
can improve cancer-related pain but rarely address spiritual
concerns (e.g., loss of meaning, peace), which can influence
the pain experience for those facing life-threatening
illness. To address these needs, we systematically developed
and pilot tested a novel psychosocial intervention called
Meaning-Centered Pain Coping Skills Training (MCPC). In this
randomized controlled trial, we aim to determine MCPC's
efficacy for reducing pain interference (primary outcome)
and improving secondary outcomes. We will also estimate
MCPC's cost-effectiveness. METHOD/DESIGN: Patients (target
N = 210) with advanced solid tumor malignancies (Stage IV)
and clinically-elevated pain interference will be enrolled
and block randomized with equal allocation to MCPC +
enhanced usual care or enhanced usual care alone. MCPC's
four, videoconferenced, 45-60 min weekly sessions will be
individually delivered by trained study therapists. Primary
(pain interference) and secondary (pain severity, anxiety
and depressive symptoms, pain self-efficacy, social support,
spiritual well-being) patient-reported outcomes will be
assessed at baseline, and 8-weeks (primary endpoint) and
12-weeks after baseline. CONCLUSION: Our MCPC intervention
is the first to systematically address the
biopsychosocial-spiritual aspects of pain in patients with
advanced cancer. If MCPC demonstrates efficacy, next steps
will involve hybrid efficacy-effectiveness and
implementation work to broaden access to this brief,
manualized, remotely-delivered intervention, with the goal
of reducing suffering in patients with life-threatening
illness.},
Doi = {10.1016/j.cct.2023.107363},
Key = {fds373557}
}
@article{fds374397,
Author = {Myers, H and Keefe, FJ and George, SZ and Kennedy, J and Lake, AD and Martinez, C and Cook, CE},
Title = {Effect of a Patient Engagement, Education, and Restructuring
of Cognitions (PEERC) approach on conservative care in
rotator cuff related shoulder pain treatment: a randomized
control trial.},
Journal = {BMC Musculoskelet Disord},
Volume = {24},
Number = {1},
Pages = {930},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1186/s12891-023-07044-y},
Abstract = {BACKGROUND: Despite similar outcomes for surgery and
physical therapy (PT), the number of surgeries to treat
rotator cuff related shoulder pain (RCRSP) is increasing.
Interventions designed to enhance treatment expectations for
PT have been shown to improve patient expectations, but no
studies have explored whether such interventions influence
patient reports of having had surgery, or being scheduled
for surgery. The purpose of this randomized clinical trial
was to examine the effect of a cognitive behavioral
intervention aimed at changing expectations for PT on
patient-report of having had or being scheduled for surgery
and on the outcomes of PT. METHODS: The Patient Engagement,
Education, and Restructuring of Cognitions (PEERC)
intervention, was designed to change expectations regarding
PT. PEERC was evaluated in a randomized, pragmatic "add-on"
trial in by randomizing patients with RCRSP to receive
either PT intervention alone (PT) or PT + PEERC.
Fifty-four (54) individuals, recruited from an outpatient
hospital-based orthopedic clinic, were enrolled in the trial
(25 randomized to PT, 29 randomized to PT + PEERC).
Outcomes assessed at enrollment, 6 weeks, discharge, and
six months after discharge included the patient report of
having had surgery, or being scheduled for surgery (primary)
and satisfaction with PT outcome, pain, and function
(secondary outcomes). RESULTS: The average age of the 54
participants was 51.81; SD = 12.54, and 63% were female.
Chronicity of shoulder pain averaged 174.61 days;
SD = 179.58. Study results showed that at the time of
six months follow up, three (12%) of the participants in the
PT alone group and one (3.4%) in the PT + PEERC group
reported have had surgery or being scheduled for surgery
(p = .32). There were no significant differences between
groups on measures of satisfaction with the outcome of PT
(p = .08), pain (p = .58) or function (p = .82).
CONCLUSIONS: In patients with RCRSP, PT plus the cognitive
behavioral intervention aimed at changing expectations for
PT provided no additional benefit compared to PT alone with
regard to patient report of having had surgery, or being
scheduled to have surgery, patient reported treatment
satisfaction with the outcome of PT, or improvements in
pain, or function. TRIAL REGISTRATION: The trial is
registered on ClinicalTrials.gov: NCT03353272
(27/11/2017).},
Doi = {10.1186/s12891-023-07044-y},
Key = {fds374397}
}
@article{fds374570,
Author = {McDermott, K and Keefe, F and Vranceanu, A-M},
Title = {Bridging the gap: Utilizing insights from exposure therapy
in the innovation of chronic musculoskeletal pain
treatment.},
Journal = {J Consult Clin Psychol},
Volume = {91},
Number = {12},
Pages = {681-682},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1037/ccp0000855},
Abstract = {For some time, the gold standard treatment for anxiety
disorders has been exposure therapy, defined as the repeated
approach of anxiety-inducing situations, memories, or
physiological sensations. Existing treatments to target fear
and avoidance of pain can be augmented by innovations from
exposure research in the anxiety disorders, including
greater emphasis on safety learning, the utilization of
imaginal exposure to catastrophic fears, and exposure to
contrasting emotions. Given that treatments to target core,
maintaining mechanisms of anxiety, including imaginal
exposures, can be administered as self-directed treatments
without therapist involvement, they represent important
avenues for ensuring the millions of people with chronic
musculosketal pain can gain access to psychosocial treatment
and reduce the interference of pain in their lives.
(PsycInfo Database Record (c) 2023 APA, all rights
reserved).},
Doi = {10.1037/ccp0000855},
Key = {fds374570}
}
@article{fds372009,
Author = {Rubenstein, D and McClernon, FJ and Powers, JM and Aston, ER and Keefe,
FJ and Sweitzer, MM},
Title = {Pain is associated with exclusive use and co-use of tobacco
and cannabis: Findings from Wave 5 (2018-2019) of the
Population Assessment of Tobacco and Health
Study.},
Journal = {Addict Behav},
Volume = {146},
Pages = {107814},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1016/j.addbeh.2023.107814},
Abstract = {INTRODUCTION: Rates of tobacco and cannabis use are
disproportionately high among individuals with pain, and
evidence suggests that pain may engender greater likelihood
of substance co-use, yielding additive risk. This study
examined national associations of pain with past-month
tobacco use, cannabis use, and co-use of tobacco and
cannabis. METHODS: Data came from a nationally
representative US sample of adults in Wave 5 (2018-2019) of
the Population Assessment of Tobacco and Health study
(N = 32,014). The sample included civilian,
non-institutionalized people who use tobacco and people who
do not use tobacco. Past-week pain intensity (0-10) was
dichotomized (0-4 no/low pain; 5-10 moderate/severe pain).
Multinomial models adjusted for demographics examined
substance use category membership (no tobacco or cannabis
use, exclusive cannabis use, exclusive tobacco use, co-use)
as a function of pain status. RESULTS: Moderate/severe pain
was associated with increased relative risk of exclusive
tobacco use (RRR [CI] 2.26 [2.05, 2.49], p <.001),
exclusive cannabis use (1.49 [1.22, 1.82], p <.001), and
co-use of tobacco and cannabis (2.79 [2.51, 3.10],
p <.001), in comparison to no tobacco or cannabis use.
Additionally, moderate/severe pain was associated with
increased risk of co-use compared to exclusive tobacco use
(1.23 [1.11, 1.37], p <.001) and exclusive cannabis use
(1.88 [1.54, 2.29], p <.001). DISCUSSION: Findings suggest
that not only is pain independently associated with greater
risk of exclusively using tobacco or cannabis, but pain is
also associated with heightened risk of co-using both
products. Future work should examine the dynamic and
potentially bidirectional relationships between pain and use
of cannabis and tobacco.},
Doi = {10.1016/j.addbeh.2023.107814},
Key = {fds372009}
}
@article{fds373697,
Author = {Basbaum, AI and Jensen, TS and Keefe, FJ},
Title = {Fifty years of pain research and clinical advances:
highlights and key trends.},
Journal = {Pain},
Volume = {164},
Number = {11S},
Pages = {S11-S15},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1097/j.pain.0000000000003058},
Abstract = {This article highlights advances in basic science
preclinical pain research, clinical research, and
psychological research occurring over the 50 years since the
International Association for the Study of Pain was founded.
It presents important findings and key trends in these 3
areas of pain science: basic science preclinical research,
clinical research, and psychological research.},
Doi = {10.1097/j.pain.0000000000003058},
Key = {fds373697}
}
@article{fds371045,
Author = {Li, Y and Reed, SD and Winger, JG and Hyland, KA and Fisher, HM and Kelleher, SA and Miller, SN and Davidian, M and Laber, EB and Keefe, FJ and Somers, TJ},
Title = {Cost-Effectiveness Analysis Evaluating Delivery Strategies
for Pain Coping Skills Training in Women With Breast
Cancer.},
Journal = {J Pain},
Volume = {24},
Number = {9},
Pages = {1712-1720},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1016/j.jpain.2023.05.004},
Abstract = {Pain coping skills training (PCST) is efficacious in
patients with cancer, but clinical access is limited. To
inform implementation, as a secondary outcome, we estimated
the cost-effectiveness of 8 dosing strategies of PCST
evaluated in a sequential multiple assignment randomized
trial among women with breast cancer and pain (N = 327).
Women were randomized to initial doses and re-randomized to
subsequent doses based on their initial response (ie, ≥30%
pain reduction). A decision-analytic model was designed to
incorporate costs and benefits associated with 8 different
PCST dosing strategies. In the primary analysis, costs were
limited to resources required to deliver PCST.
Quality-adjusted life-years (QALYs) were modeled based on
utility weights measured with the EuroQol-5 dimension
5-level at 4 assessments over 10 months. A probabilistic
sensitivity analysis was performed to account for parameter
uncertainty. Implementation of PCST initiated with the
5-session protocol was more costly ($693-853) than
strategies initiated with the 1-session protocol ($288-496).
QALYs for strategies beginning with the 5-session protocol
were greater than for strategies beginning with the
1-session protocol. With the goal of implementing PCST as
part of comprehensive cancer treatment and with
willingness-to-pay thresholds ranging beyond $20,000 per
QALY, the strategy most likely to provide the greatest
number of QALYs at an acceptable cost was a 1-session PCST
protocol followed by either 5 maintenance telephone calls
for responders or 5 sessions of PCST for nonresponders. A
PCST program with 1 initial session and subsequent dosing
based on response provides good value and improved outcomes.
PERSPECTIVE: This article presents the results of a cost
analysis of the delivery of PCST, a nonpharmacological
intervention, to women with breast cancer and pain. Results
could potentially provide important cost-related information
to health care providers and systems on the use of an
efficacious and accessible nonmedication strategy for pain
management. TRIALS REGISTRATION: ClinicalTrials.gov:
NCT02791646, registered 6/2/2016.},
Doi = {10.1016/j.jpain.2023.05.004},
Key = {fds371045}
}
@article{fds371046,
Author = {Somers, TJ and Winger, JG and Fisher, HM and Hyland, KA and Davidian, M and Laber, EB and Miller, SN and Kelleher, SA and Plumb Vilardaga and JC and Majestic, C and Shelby, RA and Reed, SD and Kimmick, GG and Keefe,
FJ},
Title = {Behavioral cancer pain intervention dosing: results of a
Sequential Multiple Assignment Randomized
Trial.},
Journal = {Pain},
Volume = {164},
Number = {9},
Pages = {1935-1941},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1097/j.pain.0000000000002915},
Abstract = {Behavioral pain management interventions are efficacious for
reducing pain in patients with cancer. However, optimal
dosing of behavioral pain interventions for pain reduction
is unknown, and this hinders routine clinical use. A
Sequential Multiple Assignment Randomized Trial (SMART) was
used to evaluate whether varying doses of Pain Coping Skills
Training (PCST) and response-based dose adaptation can
improve pain management in women with breast cancer.
Participants (N = 327) had stage I-IIIC breast cancer and a
worst pain score of > 5/10. Pain severity (a priori primary
outcome) was assessed before initial randomization (1:1
allocation) to PCST-Full (5 sessions) or PCST-Brief (1
session) and 5 to 8 weeks later. Responders ( > 30% pain
reduction) were rerandomized to a maintenance dose or no
dose and nonresponders (<30% pain reduction) to an increased
or maintenance dose. Pain severity was assessed again 5 to 8
weeks later (assessment 3) and 6 months later (assessment
4). As hypothesized, PCST-Full resulted in greater mean
percent pain reduction than PCST-Brief (M [SD] = -28.5%
[39.6%] vs M [SD]= -14.8% [71.8%]; P = 0.041). At assessment
3 after second dosing, all intervention sequences evidenced
pain reduction from assessment 1 with no differences between
sequences. At assessment 4, all sequences evidenced pain
reduction from assessment 1 with differences between
sequences ( P = 0.027). Participants initially receiving
PCST-Full had greater pain reduction at assessment 4 ( P =
0.056). Varying PCST doses led to pain reduction over time.
Intervention sequences demonstrating the most durable
decreases in pain reduction included PCST-Full. Pain Coping
Skills Training with intervention adjustment based on
response can produce sustainable pain reduction.},
Doi = {10.1097/j.pain.0000000000002915},
Key = {fds371046}
}
@article{fds371049,
Author = {Dorfman, CS and Shelby, RA and Stalls, JM and Somers, TJ and Keefe, FJ and Vilardaga, JP and Winger, JG and Mitchell, K and Ehren, C and Oeffinger,
KC},
Title = {Improving Symptom Management for Survivors of Young Adult
Cancer: Development of a Novel Intervention.},
Journal = {J Adolesc Young Adult Oncol},
Volume = {12},
Number = {4},
Pages = {472-487},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1089/jayao.2022.0100},
Abstract = {Purpose: Improved symptom management is a critical although
unmet post-treatment need for young adult (YA) cancer
survivors (aged 18-39 at diagnosis). This study aimed to
develop and refine a behavioral symptom management
intervention for YA survivors. Methods: Phase I: YA
survivors (N = 21) and oncology providers (N = 11)
completed individual interviews and an online, self-report
assessment to examine symptom experiences, the need for a
behavioral symptom management intervention for YAs, and
perceptions about potential intervention components,
structure, and format. Phase II: YA survivors (N = 10)
completed user testing sessions, providing feedback on the
prototype intervention materials (paper manual and mobile
application), and completed an online assessment.
Quantitative data were examined using descriptive
statistics. Rapid qualitative analysis, a methodologically
rigorous standardized approach, was used. Results: Pain,
fatigue, and distress were ranked as top concerns by most
YAs and providers. Phase I interviews underscored the need
for a symptom management intervention for YAs. YAs and
providers highlighted potential coping strategies and
program format/structure suggestions (e.g., small group
format) to best meet YAs' needs. A prototype intervention
was developed combining the following: traditional
behavioral symptom coping skills; home-based physical
activity; strategies from Acceptance and Commitment Therapy
and Meaning-Centered Psychotherapy; and strategies to foster
self-compassion. Phase II user testing sessions highlighted
strengths and suggestions for refining the prototype
materials. Conclusion: Post-treatment symptoms are common
for YAs. A tailored behavioral symptom management program
was developed and refined with input from YAs and providers
and will be examined for feasibility and acceptability in a
pilot randomized controlled trial. Clinical Trial:
Clinicaltrials.gov identifier NCT04035447.},
Doi = {10.1089/jayao.2022.0100},
Key = {fds371049}
}
@article{fds370880,
Author = {Winger, JG and Kelleher, SA and Ramos, K and Check, DK and Yu, JA and Powell, VD and Lerebours, R and Olsen, MK and Keefe, FJ and Steinhauser,
KE and Porter, LS and Breitbart, WS and Somers, TJ},
Title = {Meaning-centered pain coping skills training for patients
with metastatic cancer: Results of a randomized controlled
pilot trial.},
Journal = {Psychooncology},
Volume = {32},
Number = {7},
Pages = {1096-1105},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1002/pon.6151},
Abstract = {OBJECTIVE: For patients with advanced cancer, pain is a
common and debilitating symptom that can negatively impact
physical, emotional, and spiritual well-being. This trial
examined the feasibility and initial effects of
Meaning-Centered Pain Coping Skills Training (MCPC), a
cognitive-behavioral pain management intervention with an
emphasis on enhancing meaning (i.e., a personal sense of
purpose, worth, and significance) and peace. METHODS: We
enrolled 60 adults with stage IV solid tumor cancers and
moderate-severe pain between February 2021 and February
2022. Participants were randomized 1:1 to MCPC + usual
care or usual care alone. Meaning-Centered Pain Coping
Skills Training consisted of four weekly 60-min individual
sessions via videoconference or telephone, delivered by a
trained therapist using a manualized protocol. Participants
completed validated measures of pain severity, pain
interference, pain self-efficacy, spiritual well-being
(i.e., meaning, peace, and faith), and psychological
distress at baseline and 5-week and 10-week follow-ups.
RESULTS: All feasibility metrics exceeded prespecified
benchmarks. Fifty-eight percent of screened patients were
eligible, and 69% of eligible patients consented. Of those
assigned to MCPC, 93% completed all sessions and 100% of
those who completed follow-ups reported using coping skills
weekly. Retention was strong at 5-week (85%) and 10-week
(78%) follow-ups. Meaning-Centered Pain Coping Skills
Training participants reported better scores than control
participants across outcome measures, including
moderate-to-large sized differences at 10-week follow-up in
pain severity (Cohen's d = -0.75 [95% confidence interval:
-1.36, -0.14]), pain interference (d = -0.82 [-1.45,
-0.20]), and pain self-efficacy (d = 0.74 [0.13, 1.35]).
CONCLUSIONS: MCPC is a highly feasible, engaging, and
promising approach for improving pain management in advanced
cancer. Future efficacy testing is warranted. TRIAL
REGISTRATION: ClinicalTrials.gov Identifier: NCT04431830,
registered 16 June 2020.},
Doi = {10.1002/pon.6151},
Key = {fds370880}
}
@article{fds370237,
Author = {Hyland, KA and Amaden, GH and Diachina, AK and Miller, SN and Dorfman,
CS and Berchuck, SI and Winger, JG and Somers, TJ and Keefe, FJ and Uronis,
HE and Kelleher, SA},
Title = {mHealth Coping Skills Training for Symptom Management
(mCOPE) for colorectal cancer patients in early to
mid-adulthood: Study protocol for a randomized controlled
trial.},
Journal = {Contemp Clin Trials Commun},
Volume = {33},
Pages = {101126},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1016/j.conctc.2023.101126},
Abstract = {BACKGROUND: Colorectal cancer (CRC) patients in early to
mid-adulthood (≤50 years) are challenged by high symptom
burden (i.e., pain, fatigue, distress) and age-related
stressors (e.g., managing family, work). Cognitive
behavioral theory (CBT)-based coping skills training
interventions reduce symptoms and improve quality of life in
cancer patients. However, traditional CBT-based
interventions are not accessible to these patients (e.g.,
in-person sessions, during work day), nor designed to
address symptoms within the context of this stage of life.
We developed a mobile health (mHealth) coping skills
training program for pain, fatigue and distress (mCOPE) for
CRC patients in early to mid-adulthood. We utilize a
randomized controlled trial to test the extent to which
mCOPE reduces pain, fatigue and distress (multiple primary
outcomes) and improves quality of life and symptom
self-efficacy (secondary outcomes). METHODS/DESIGN: Patients
(N = 160) ≤50 years with CRC endorsing pain, fatigue
and/or distress are randomized 1:1 to mCOPE or standard
care. mCOPE is a five-session CBT-based coping skills
training program (e.g., relaxation, activity pacing,
cognitive restructuring) that was adapted for CRC patients
in early to mid-adulthood. mCOPE utilizes mHealth technology
(e.g., videoconference, mobile app) to deliver coping skills
training, capture symptom and skills use data, and provide
personalized support and feedback. Self-report assessments
are completed at baseline, post-treatment (5-8 weeks
post-baseline; primary endpoint), and 3- and 6-months later.
CONCLUSIONS: mCOPE is innovative and potentially impactful
for CRC patients in early to mid-adulthood. Hypothesis
confirmation would demonstrate initial efficacy of a mHealth
cognitive behavioral intervention to reduce symptom burden
in younger CRC patients.},
Doi = {10.1016/j.conctc.2023.101126},
Key = {fds370237}
}
@article{fds371125,
Author = {Hohenschurz-Schmidt, D and Vase, L and Scott, W and Annoni, M and Ajayi,
OK and Barth, J and Bennell, K and Berna, C and Bialosky, J and Braithwaite, F and Finnerup, NB and Williams, ACDC and Carlino, E and Cerritelli, F and Chaibi, A and Cherkin, D and Colloca, L and Côté, P and Darnall, BD and Evans, R and Fabre, L and Faria, V and French, S and Gerger, H and Häuser, W and Hinman, RS and Ho, D and Janssens, T and Jensen, K and Johnston, C and Juhl Lunde and S and Keefe, F and Kerns, RD and Koechlin, H and Kongsted, A and Michener, LA and Moerman, DE and Musial,
F and Newell, D and Nicholas, M and Palermo, TM and Palermo, S and Peerdeman, KJ and Pogatzki-Zahn, EM and Puhl, AA and Roberts, L and Rossettini, G and Tomczak Matthiesen and S and Underwood, M and Vaucher,
P and Vollert, J and Wartolowska, K and Weimer, K and Werner, CP and Rice,
ASC and Draper-Rodi, J},
Title = {Recommendations for the development, implementation, and
reporting of control interventions in efficacy and
mechanistic trials of physical, psychological, and
self-management therapies: the CoPPS Statement.},
Journal = {BMJ},
Volume = {381},
Pages = {e072108},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1136/bmj-2022-072108},
Doi = {10.1136/bmj-2022-072108},
Key = {fds371125}
}
@article{fds371126,
Author = {Bronfort, G and Delitto, A and Schneider, M and Heagerty, PJ and Chou,
R and Connett, J and Evans, R and George, S and Glick, RM and Greco, C and Hanson, L and Keefe, F and Leininger, B and Licciardone, J and McFarland, C and Meier, E and Schulz, C and Turk,
D},
Title = {Effectiveness of spinal manipulation and biopsychosocial
self-management compared to medical care for low back pain:
a randomized trial study protocol.},
Journal = {BMC Musculoskelet Disord},
Volume = {24},
Number = {1},
Pages = {415},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1186/s12891-023-06549-w},
Abstract = {BACKGROUND: Chronic low back pain (cLBP) is widespread,
costly, and burdensome to patients and health systems.
Little is known about non-pharmacological treatments for the
secondary prevention of cLBP. There is some evidence that
treatments addressing psychosocial factors in higher risk
patients are more effective than usual care. However, most
clinical trials on acute and subacute LBP have evaluated
interventions irrespective of prognosis. METHODS: We have
designed a phase 3 randomized trial with a 2 × 2
factorial design. The study is also a Hybrid type 1 trial
with focus on intervention effectiveness while
simultaneously considering plausible implementation
strategies. Adults (n = 1000) with acute/subacute LBP at
moderate to high risk of chronicity based on the STarT Back
screening tool will be randomized in to 1 of 4 interventions
lasting up to 8 weeks: supported self-management (SSM),
spinal manipulation therapy (SMT), both SSM and SMT, or
medical care. The primary objective is to assess
intervention effectiveness; the secondary objective is to
assess barriers and facilitators impacting future
implementation. Primary effectiveness outcome measures are:
(1) average pain intensity over 12 months post-randomization
(pain, numerical rating scale); (2) average low back
disability over 12 months post-randomization (Roland-Morris
Disability Questionnaire); (3) prevention of cLBP that is
impactful at 10-12 months follow-up (LBP impact from the
PROMIS-29 Profile v2.0). Secondary outcomes include:
recovery, PROMIS-29 Profile v2.0 measures to assess pain
interference, physical function, anxiety, depression,
fatigue, sleep disturbance, and ability to participate in
social roles and activities. Other patient-reported measures
include LBP frequency, medication use, healthcare
utilization, productivity loss, STarT Back screening tool
status, patient satisfaction, prevention of chronicity,
adverse events, and dissemination measures. Objective
measures include the Quebec Task Force Classification, Timed
Up & Go Test, the Sit to Stand Test, and the Sock Test
assessed by clinicians blinded to the patients' intervention
assignment. DISCUSSION: By targeting those subjects at
higher risk this trial aims to fill an important gap in the
scientific literature regarding the effectiveness of
promising non-pharmacological treatments compared to medical
care for the management of patients with an acute episode of
LBP and the prevention of progression to a severe chronic
back problem. TRIAL REGISTRATION: ClinicalTrials.gov
Identifier: NCT03581123.},
Doi = {10.1186/s12891-023-06549-w},
Key = {fds371126}
}
@article{fds370043,
Author = {Simon, CB and Hicks, GE and Pieper, CF and Byers Kraus and V and Keefe, FJ and Colón-Emeric, C},
Title = {A Novel Movement-Evoked Pain Provocation Test for Older
Adults With Persistent Low Back Pain: Safety, Feasibility,
and Associations With Self-reported Physical Function and
Usual Gait Speed.},
Journal = {Clin J Pain},
Volume = {39},
Number = {4},
Pages = {166-174},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1097/AJP.0000000000001101},
Abstract = {OBJECTIVES: Low back pain (LBP) is highly prevalent and
disabling for older adults. Movement-evoked pain is an
emerging measure that may help to predict disability; but is
not currently a part of geriatric LBP clinical care. This
study tested the safety and feasibility of a new
Movement-Evoked Provocation Test for Low Back Pain in Older
Adults (MEPLO). We also compared associations between
movement-evoked pain via 2 different scoring methods and
disability-associated outcomes. MATERIALS AND METHODS:
Thirty-nine older adults with persistent LBP provided
baseline recalled and resting pain ratings, self-reported
physical function, and usual gait speed. Participants then
completed MEPLO, involving 4 tasks essential for functional
independence: chair rises, trunk rotation, reaching, and
walking. Movement-evoked pain was then quantified using the
traditional change score (delta) method of pain premovement
to postmovement; and also, a new aggregate method that
combines pain ratings after the 4 tasks. RESULTS: No safety
or feasibility issues were identified. Compared with the
delta score, the aggregate score was more strongly
associated with self-reported physical function (beta:
-0.495 vs. -0.090) and usual gait speed (beta: -0.450 vs.
-0.053). Similarly, the aggregate score was more strongly
associated with self-reported physical function than
recalled and resting pain (beta: -0.470, -0.283, and 0.136,
respectively). DISCUSSION: This study shows the safety and
feasibility of testing movement-evoked pain in older adults
with persistent LBP, and its potential superiority to
traditional pain measures. Future studies must validate
these findings and test the extent to which MEPLO is
implementable to change with geriatric LBP standard of
care.},
Doi = {10.1097/AJP.0000000000001101},
Key = {fds370043}
}
@article{fds370161,
Author = {Palermo, TM and Davis, KD and Bouhassira, D and Hurley, RW and Katz, JD and Keefe, FJ and Schatman, M and Turk, DC and Yarnitsky,
D},
Title = {Promoting inclusion, diversity and equity in pain
science.},
Journal = {Eur J Pain},
Volume = {27},
Number = {4},
Pages = {451-456},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1002/ejp.2087},
Doi = {10.1002/ejp.2087},
Key = {fds370161}
}
@article{fds371047,
Author = {Kerns, RD and Davis, AF and Fritz, JM and Keefe, FJ and Peduzzi, P and Rhon, DI and Taylor, SL and Vining, R and Yu, Q and Zeliadt, SB and George,
SZ},
Title = {Intervention Fidelity in Pain Pragmatic Trials for
Nonpharmacologic Pain Management: Nuanced Considerations for
Determining PRECIS-2 Flexibility in Delivery and
Adherence.},
Journal = {J Pain},
Volume = {24},
Number = {4},
Pages = {568-574},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1016/j.jpain.2022.12.008},
Abstract = {Nonpharmacological treatments are considered first-line pain
management strategies, but they remain clinically underused.
For years, pain-focused pragmatic clinical trials (PCTs)
have generated evidence for the enhanced use of
nonpharmacological interventions in routine clinical
settings to help overcome implementation barriers. The
Pragmatic Explanatory Continuum Indicator Summary (PRECIS-2)
framework describes the degree of pragmatism across 9 key
domains. Among these, "flexibility in delivery" and
"flexibility in adherence," address a key goal of pragmatic
research by tailoring approaches to settings in which people
receive routine care. However, to maintain scientific and
ethical rigor, PCTs must ensure that flexibility features do
not compromise delivery of interventions as designed, such
that the results are ethically and scientifically sound. Key
principles of achieving this balance include clear
definitions of intervention core components, intervention
monitoring and documentation that is sufficient but not
overly burdensome, provider training that meets the demands
of delivering an intervention in real-world settings, and
use of an ethical lens to recognize and avoid potential
trial futility when necessary and appropriate. PERSPECTIVE:
This article presents nuances to be considered when applying
the PRECIS-2 framework to describe pragmatic clinical
trials. Trials must ensure that patient-centered treatment
flexibility does not compromise delivery of interventions as
designed, such that measurement and analysis of treatment
effects is reliable.},
Doi = {10.1016/j.jpain.2022.12.008},
Key = {fds371047}
}
@article{fds370044,
Author = {Mayhew, M and Balderson, BH and Cook, AJ and Dickerson, JF and Elder,
CR and Firemark, AJ and Haller, IV and Justice, M and Keefe, FJ and McMullen, CK and O'Keeffe-Rosetti, MC and Owen-Smith, AA and Rini, C and Schneider, JL and Von Korff and M and Wandner, LD and DeBar,
LL},
Title = {Comparing the clinical and cost-effectiveness of remote
(telehealth and online) cognitive behavioral therapy-based
treatments for high-impact chronic pain relative to usual
care: study protocol for the RESOLVE multisite randomized
control trial.},
Journal = {Trials},
Volume = {24},
Number = {1},
Pages = {196},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1186/s13063-023-07165-8},
Abstract = {BACKGROUND: Cognitive behavioral therapy for chronic pain
(CBT-CP) is an effective but underused treatment for
high-impact chronic pain. Increased access to CBT-CP
services for pain is of critical public health importance,
particularly for rural and medically underserved populations
who have limited access due to these services being
concentrated in urban and high income areas. Making CBT-CP
widely available and more affordable could reduce barriers
to CBT-CP use. METHODS: As part of the National Institutes
of Health Helping to End Addiction Long-term® (NIH HEAL)
initiative, we designed and implemented a comparative
effectiveness, 3-arm randomized control trial comparing
remotely delivered telephonic/video and online CBT-CP-based
services to usual care for patients with high-impact chronic
pain. The RESOLVE trial is being conducted in 4 large
integrated healthcare systems located in Minnesota, Georgia,
Oregon, and Washington state and includes demographically
diverse populations residing in urban and rural areas. The
trial compares (1) an 8-session, one-on-one, professionally
delivered telephonic/video CBT-CP program; and (2) a
previously developed and tested 8-session online
CBT-CP-based program (painTRAINER) to (3) usual care
augmented by a written guide for chronic pain management.
Participants are followed for 1 year post-allocation and
are assessed at baseline, and 3, 6, and 12 months
post-allocation. The primary outcome is minimal clinically
important difference (MCID; ≥ 30% reduction) in pain
severity (composite of pain intensity and pain-related
interference) assessed by a modified 11-item version of the
Brief Pain Inventory-Short Form at 3 months. Secondary
outcomes include pain severity, pain intensity, and
pain-related interference scores, quality of life measures,
and patient global impression of change at 3, 6, and
12 months. Cost-effectiveness is assessed by incremental
cost per additional patient with MCID in primary outcome and
by cost per quality-adjusted life year achieved. Outcome
assessment is blinded to group assignment. DISCUSSION: This
large-scale trial provides a unique opportunity to
rigorously evaluate and compare the clinical and
cost-effectiveness of 2 relatively low-cost and scalable
modalities for providing CBT-CP-based treatments to persons
with high-impact chronic pain, including those residing in
rural and other medically underserved areas with limited
access to these services. TRIAL REGISTRATION:
ClinicalTrials.gov NCT04523714. This trial was registered on
24 August 2020.},
Doi = {10.1186/s13063-023-07165-8},
Key = {fds370044}
}
@article{fds370045,
Author = {Burns, JW and Jensen, MP and Gerhart, J and Thorn, BE and Lillis, TA and Carmody, J and Keefe, F},
Title = {Cognitive therapy, mindfulness-based stress reduction, and
behavior therapy for people with chronic low back pain: A
comparative mechanisms study.},
Journal = {J Consult Clin Psychol},
Volume = {91},
Number = {3},
Pages = {171-187},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1037/ccp0000801},
Abstract = {OBJECTIVE: Cognitive therapy (CT), mindfulness-based stress
reduction (MBSR), and behavior therapy (BT) for chronic pain
treatment produce outcome improvements. Evidence also
suggests that changes in putative therapeutic mechanisms are
associated with changes in outcomes. Nonetheless,
methodological limitations preclude clear understanding of
how psychosocial chronic pain treatments work. In this
comparative mechanism study, we examined evidence for
specific and shared mechanism effects across the three
treatments. METHOD: CT, MBSR, BT, and treatment as usual
(TAU) were compared in people with chronic low back pain (N
= 521). Eight individual sessions were administered with
weekly assessments of "specific" mechanisms (pain
catastrophizing, mindfulness, behavior activation) and
outcomes. RESULTS: CT, MBSR, and BT produced similar pre- to
posttreatment effects on all mechanism variables, and all
three active treatments produced greater improvements than
TAU. Participant ratings of expectations of benefit and
working alliance were similar across treatments. Lagged and
cross-lagged analyses revealed that prior week changes in
both mechanism and outcome factors predicted next week
changes in their counterparts. Analyses of variance
contributions suggested that changes in pain catastrophizing
and pain self-efficacy were consistent unique predictors of
subsequent outcome changes. CONCLUSIONS: Findings support
the operation of shared mechanisms over specific ones. Given
significant lagged and cross-lagged effects, unidirectional
conceptualizations-mechanism to outcome-need to be expanded
to include reciprocal effects. Thus, prior week changes in
pain-related cognitions could predict next week changes in
pain interference which in turn could predict next week
changes in pain-related cognitions, in what may be an upward
spiral of improvement. (PsycInfo Database Record (c) 2023
APA, all rights reserved).},
Doi = {10.1037/ccp0000801},
Key = {fds370045}
}
@article{fds368120,
Author = {Palermo, TM and Davis, KD and Bouhassira, D and Hurley, RW and Katz, JD and Keefe, FJ and Schatman, M and Turk, DC and Yarnitsky,
D},
Title = {Promoting Inclusion, Diversity, and Equity in Pain
Science.},
Journal = {J Pain},
Volume = {24},
Number = {2},
Pages = {187-191},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1016/j.jpain.2022.11.005},
Doi = {10.1016/j.jpain.2022.11.005},
Key = {fds368120}
}
@article{fds369116,
Author = {Palermo, TM and Davis, KD and Bouhassira, D and Hurley, RW and Katz, JD and Keefe, FJ and Schatman, M and Turk, DC and Yarnitsky,
D},
Title = {Promoting Inclusion, Diversity, and Equity in Pain
Science.},
Journal = {Clin J Pain},
Volume = {39},
Number = {2},
Pages = {55-59},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1097/AJP.0000000000001094},
Doi = {10.1097/AJP.0000000000001094},
Key = {fds369116}
}
@article{fds369117,
Author = {Palermo, TM and Davis, KD and Bouhassira, D and Hurley, RW and Katz, JD and Keefe, FJ and Schatman, M and Turk, DC and Yarnitsky,
D},
Title = {Promoting Inclusion, Diversity, and Equity in Pain
Science.},
Journal = {Pain Med},
Volume = {24},
Number = {2},
Pages = {105-109},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1093/pm/pnac204},
Doi = {10.1093/pm/pnac204},
Key = {fds369117}
}
@article{fds368585,
Author = {Garland, EL and Roberts, RL and Hanley, AW and Zeidan, F and Keefe,
FJ},
Title = {The Mindful Reappraisal of Pain Scale (MRPS): Validation of
a New Measure of Psychological Mechanisms of
Mindfulness-Based Analgesia.},
Journal = {Mindfulness (N Y)},
Volume = {14},
Number = {1},
Pages = {192-204},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1007/s12671-022-02034-y},
Abstract = {OBJECTIVES: Mindfulness is theorized to decrease the
affective amplification of chronic pain by facilitating a
shift from emotionally-laden, catastrophic pain appraisals
of nociceptive input to reappraising chronic pain as an
innocuous sensory signal that does not signify harm.
Understanding of these hypothetical psychological mechanisms
of mindfulness-based analgesia has been limited by a lack of
direct measures. We conducted a series of psychometric and
experimental studies to develop and validate the Mindful
Reappraisal of Pain Sensations Scale (MPRS). METHODS: After
item generation, we conducted exploratory and confirmatory
factor analyses of the MRPS in samples of opioid-treated
chronic pain patients both before (n=450; n=90) and after
(n=222) participating in Mindfulness-Oriented Recovery
Enhancement (MORE). We then examined the convergent and
divergent validity of the MRPS. Finally, in data from a
randomized clinical trial (n=250), the MRPS was tested as a
mediator of the effects of MORE on reducing chronic pain
severity. RESULTS: Exploratory and confirmatory factor
analyses demonstrated the single-factor structure of the
MRPS. The MRPS also evidenced convergent and divergent
validity. Mindfulness training through MORE significantly
increased MRPS scores relative to supportive psychotherapy
(F4,425.03 = 16.15, p < .001). Changes in MRPS scores
statistically mediated the effect of MORE on reducing
chronic pain severity through 9-month follow-up.
CONCLUSIONS: Taken together, these studies demonstrate that
the MRPS is a psychometrically sound and valid measure of
novel analgesic mechanisms of mindfulness including
attentional disengagement from affective pain appraisals and
interoceptive exposure to pain sensations.},
Doi = {10.1007/s12671-022-02034-y},
Key = {fds368585}
}
@article{fds369142,
Author = {Palermo, TM and Davis, KD and Bouhassira, D and Hurley, RW and Katz, JD and Keefe, FJ and Schatman, M and Turk, DC and Yarnitsky,
D},
Title = {Promoting inclusion, diversity, and equity in pain
science.},
Journal = {Pain reports},
Volume = {8},
Number = {1},
Pages = {e1063},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1097/pr9.0000000000001063},
Doi = {10.1097/pr9.0000000000001063},
Key = {fds369142}
}
@article{fds369397,
Author = {Palermo, TM and Davis, KD and Bouhassira, D and Hurley, RW and Katz, JD and Keefe, FJ and Schatman, ME and Turk, DC and Yarnitsky,
D},
Title = {Promoting Inclusion, Diversity, and Equity in Pain
Science.},
Journal = {J Pain Res},
Volume = {16},
Pages = {301-306},
Year = {2023},
url = {http://dx.doi.org/10.2147/JPR.S401985},
Doi = {10.2147/JPR.S401985},
Key = {fds369397}
}
@article{fds369895,
Author = {Palermo, TM and Davis, KD and Bouhassira, D and Hurley, RW and Katz, JD and Keefe, FJ and Schatman, M and Turk, DC and Yarnitsky,
D},
Title = {Promoting inclusion, diversity, and equity in pain
science.},
Journal = {Can J Pain},
Volume = {7},
Number = {1},
Pages = {2161272},
Year = {2023},
url = {http://dx.doi.org/10.1080/24740527.2022.2161272},
Doi = {10.1080/24740527.2022.2161272},
Key = {fds369895}
}
@article{fds372550,
Author = {Martin, S and Arthur, SS and Bovbjerg, DH and Huang, M and Keefe, FJ and Manculich, J and Soo, MSC and Zuley, ML and Shelby,
RA},
Title = {The Role Of Psychological Factors As Predictors Of
Mammography Pain Experienced By Breast Cancer Survivors
During Their First Surveillance Screening After
Breast-Conserving Surgery},
Journal = {JOURNAL OF PAIN},
Volume = {24},
Number = {4},
Pages = {100-100},
Year = {2023},
Key = {fds372550}
}
@article{fds373698,
Author = {Winger, JG and Kelleher, SA and Ramos, K and Check, DK and Lerebours,
RC and Olsen, MK and Keefe, FJ and Steinhauser, KE and Porter, LS and Somers, TJ},
Title = {MEANING-CENTERED PAIN COPING SKILLS TRAINING FOR PATIENTS
WITH ADVANCED CANCER: RESULTS OF A RANDOMIZED CONTROLLED
PILOT TRIAL},
Journal = {ANNALS OF BEHAVIORAL MEDICINE},
Volume = {57},
Pages = {S285-S285},
Year = {2023},
Key = {fds373698}
}
%% Keefe, Richard S.
@article{fds372237,
Author = {Darrow, SM and Pizzagalli, DA and Smoski, M and Mathew, SJ and Nurnberger, J and Lisanby, SH and Iosifescu, D and Murrough, JW and Yang, H and Weiner, RD and Sanacora, G and Keefe, RSE and Song, A and Goodman, W and Whitton, AE and Potter, WZ and Krystal,
AD},
Title = {Using latent profile analyses to classify subjects with
anhedonia based on reward-related measures obtained in the
FAST-MAS study.},
Journal = {J Affect Disord},
Volume = {339},
Pages = {584-592},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1016/j.jad.2023.07.081},
Abstract = {BACKGROUND: Growing evidence indicates that anhedonia is a
multifaceted construct. This study examined the possibility
of identifying subgroups of people with anhedonia using
multiple reward-related measures to provide greater
understanding the Research Domain Criteria's Positive
Valence Systems Domain and pathways for developing
treatments. METHODS: Latent profile analysis of baseline
data from a study that examined the effects of a novel kappa
opioid receptor (KOR) antagonist drug on measures and
biomarkers associated with anhedonia was used to identify
subgroups. Measures included ventral striatal activation
during the Monetary Incentive Delay task, response bias in
the Probabilistic Reward Task, reward valuation scores from
the Effort-Expenditure for Rewards Task, and scores from
reward-related self-report measures. RESULTS: Two subgroups
were identified, which differed on self-report measures of
reward. Participants in the subgroup reporting more
anhedonia also reported more depression and had greater
illness severity and functional impairments. Graphs of
change with treatment showed a trend for the less severe
subgroup to demonstrate higher response to KOR antagonist
treatment on the neuroimaging measure, probabilistic reward
task, and ratings of functioning; the subgroup with greater
severity showed a trend for higher treatment response on
reward-related self-report measures. LIMITATIONS: The main
limitations include the small sample size and exploratory
nature of analyses. CONCLUSIONS: Evidence of possible
dissociation between self-reported measures of anhedonia and
other measures with respect to treatment response emerged.
These results highlight the importance for future research
to consider severity of self-reported reward-related
deficits and how the relationship across measurement methods
may vary with severity.},
Doi = {10.1016/j.jad.2023.07.081},
Key = {fds372237}
}
@article{fds374358,
Author = {Lutz, J and Pratap, A and Lenze, EJ and Bestha, D and Lipschitz, JM and Karantzoulis, S and Vaidyanathan, U and Robin, J and Horan, W and Brannan, S and Mittoux, A and Davis, MC and Lakhan, SE and Keefe,
R},
Title = {Innovative Technologies in CNS Trials: Promises and Pitfalls
for Recruitment, Retention, and Representativeness},
Journal = {Innovations in Clinical Neuroscience},
Volume = {20},
Number = {7-9},
Pages = {40-46},
Year = {2023},
Month = {July},
Abstract = {Objective: Recruitment of a sufficiently large and
representative patient sample and its retention during
central nervous system (CNS) trials presents major
challenges for study sponsors. Technological advances are
reshaping clinical trial operations to meet these
challenges, and the COVID-19 pandemic further accelerated
this development. Method of Research: The International
Society for CNS Clinical Trials and Methodology (ISCTM;
www.isctm.org) Innovative Technologies for CNS Trials
Working Group surveyed the state of technological
innovations for improved recruitment and retention and
assessed their promises and pitfalls. Results: Online
advertisement and electronic patient registries can enhance
recruitment, but challenges with sample representativeness,
conversion rates from eligible prescreening to enrolled
patients, data privacy and security, and patient
identification remain hurdles for optimal use of these
technologies. Electronic medical records (EMR) mining with
artificial intelligence (AI)/machine learning (ML) methods
is promising but awaits translation into trials. During the
study treatment phase, technological innovations
increasingly support participant retention, including
adherence with the investigational treatment. Digital tools
for adherence and retention support take many forms,
including patient-centric communication channels between
researchers and participants, real-time study reminders, and
digital behavioral interventions to increase study
compliance. However, such tools add technical complexities
to trials, and their impact on the generalizability of
results are largely unknown. Conclusion: Overall, the group
found a scarcity of systematic data directly assessing the
impact of technological innovations on study recruitment and
retention in CNS trials, even for strategies with already
high adoption, such as online recruitment. Given the added
complexity and costs associated with most technological
innovations, such data is needed to fully harness
technologies for CNS trials and drive further
adoption.},
Key = {fds374358}
}
@article{fds371571,
Author = {McCutcheon, RA and Keefe, RSE and McGuire, PK},
Title = {Cognitive impairment in schizophrenia: aetiology,
pathophysiology, and treatment.},
Journal = {Mol Psychiatry},
Volume = {28},
Number = {5},
Pages = {1902-1918},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1038/s41380-023-01949-9},
Abstract = {Cognitive deficits are a core feature of schizophrenia,
account for much of the impaired functioning associated with
the disorder and are not responsive to existing treatments.
In this review, we first describe the clinical presentation
and natural history of these deficits. We then consider
aetiological factors, highlighting how a range of similar
genetic and environmental factors are associated with both
cognitive function and schizophrenia. We then review the
pathophysiological mechanisms thought to underlie cognitive
symptoms, including the role of dopamine, cholinergic
signalling and the balance between GABAergic interneurons
and glutamatergic pyramidal cells. Finally, we review the
clinical management of cognitive impairments and candidate
novel treatments.},
Doi = {10.1038/s41380-023-01949-9},
Key = {fds371571}
}
@article{fds371570,
Author = {McCutcheon, RA and Keefe, RSE and McGuire, PK},
Title = {Correction: Cognitive impairment in schizophrenia:
aetiology, pathophysiology, and treatment.},
Journal = {Mol Psychiatry},
Volume = {28},
Number = {5},
Pages = {1919},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1038/s41380-023-01984-6},
Doi = {10.1038/s41380-023-01984-6},
Key = {fds371570}
}
@article{fds371747,
Author = {Zhang, L and Lizano, P and Xu, Y and Rubin, LH and Lee, AM and Lencer, R and Reilly, JL and Keefe, RSE and Keedy, SK and Pearlson, GD and Clementz,
BA and Keshavan, MS and Gershon, ES and Tamminga, CA and Sweeney, JA and Hill, SK and Bishop, JR},
Title = {Peripheral inflammation is associated with impairments of
inhibitory behavioral control and visual sensorimotor
function in psychotic disorders.},
Journal = {Schizophrenia Research},
Volume = {255},
Pages = {69-78},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1016/j.schres.2023.03.030},
Abstract = {Elevated markers of peripheral inflammation are common in
psychosis spectrum disorders and have been associated with
brain anatomy, pathology, and physiology as well as clinical
outcomes. Preliminary evidence suggests a link between
inflammatory cytokines and C-reactive protein (CRP) with
generalized cognitive impairments in a subgroup of
individuals with psychosis. Whether these patients with
elevated peripheral inflammation demonstrate deficits in
specific cognitive domains remains unclear. To examine this,
seventeen neuropsychological and sensorimotor tasks and
thirteen peripheral inflammatory and microvascular markers
were quantified in a subset of B-SNIP consortium
participants (129 psychosis, 55 healthy controls). Principal
component analysis was conducted across the inflammatory
markers, resulting in five inflammation factors. Three
discrete latent cognitive domains (Visual Sensorimotor,
General Cognitive Ability, and Inhibitory Behavioral
Control) were characterized based on the neurobehavioral
battery and examined in association with inflammation
factors. Hierarchical clustering analysis identified
cognition-sensitive high/low inflammation subgroups. Among
persons with psychotic disorders but not healthy controls,
higher inflammation scores had significant associations with
impairments of Inhibitory Control (R2 = 0.100,
p-value = 2.69e-4, q-value = 0.004) and suggestive
associations with Visual Sensorimotor function
(R2 = 0.039, p-value = 0.024, q-value = 0.180), but
not with General Cognitive Ability (R2 = 0.015,
p-value = 0.162). Greater deficits in Inhibitory Control
were observed in the high inflammation patient subgroup,
which represented 30.2 % of persons with psychotic
disorders, as compared to the low inflammation psychosis
subgroup. These findings indicate that inflammation
dysregulation may differentially impact specific
neurobehavioral domains across psychotic disorders,
particularly performance on tasks requiring ongoing
behavioral monitoring and control.},
Doi = {10.1016/j.schres.2023.03.030},
Key = {fds371747}
}
@article{fds371818,
Author = {Cecchi, M and Adachi, M and Basile, A and Buhl, DL and Chadchankar, H and Christensen, S and Christian, E and Doherty, J and Fadem, KC and Farley,
B and Forman, MS and Honda, S and Johannesen, J and Kinon, BJ and Klamer,
D and Marino, MJ and Missling, C and O'Donnell, P and Piser, T and Puryear,
CB and Quirk, MC and Rotte, M and Sanchez, C and Smith, DG and Uslaner, JM and Javitt, DC and Keefe, RSE and Mathalon, D and Potter, WZ and Walling,
DP and Ereshefsky, L},
Title = {Validation of a suite of ERP and QEEG biomarkers in a
pre-competitive, industry-led study in subjects with
schizophrenia and healthy volunteers.},
Journal = {Schizophrenia Research},
Volume = {254},
Pages = {178-189},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1016/j.schres.2023.02.018},
Abstract = {OBJECTIVE: Complexity and lack of standardization have
mostly limited the use of event-related potentials (ERPs)
and quantitative EEG (QEEG) biomarkers in drug development
to small early phase trials. We present results from a
clinical study on healthy volunteers (HV) and patients with
schizophrenia (SZ) that assessed test-retest, group
differences, variance, and correlation with functional
assessments for ERP and QEEG measures collected at clinical
and commercial trial sites with standardized instrumentation
and methods, and analyzed through an automated data analysis
pipeline. METHODS: 81 HV and 80 SZ were tested at one of
four study sites. Subjects were administered two ERP/EEG
testing sessions on separate visits. Sessions included a
mismatch negativity paradigm, a 40 Hz auditory steady-state
response paradigm, an eyes-closed resting state EEG, and an
active auditory oddball paradigm. SZ subjects were also
tested on the Brief Assessment of Cognition (BAC), Positive
and Negative Syndrome Scale (PANSS), and Virtual Reality
Functional Capacity Assessment Tool (VRFCAT). RESULTS:
Standardized ERP/EEG instrumentation and methods ensured few
test failures. The automated data analysis pipeline allowed
for near real-time analysis with no human intervention.
Test-retest reliability was fair-to-excellent for most of
the outcome measures. SZ subjects showed significant
deficits in ERP and QEEG measures consistent with published
academic literature. A subset of ERP and QEEG measures
correlated with functional assessments administered to the
SZ subjects. CONCLUSIONS: With standardized instrumentation
and methods, complex ERP/EEG testing sessions can be
reliably performed at clinical and commercial trial sites to
produce high-quality data in near real-time.},
Doi = {10.1016/j.schres.2023.02.018},
Key = {fds371818}
}
@article{fds370724,
Author = {Feber, L and Peter, N and Schneider-Thoma, J and Siafis, S and Bighelli,
I and Hansen, W-P and Prates Baldez and D and Salanti, G and Keefe, RSE and Engel, RR and Leucht, S},
Title = {Antipsychotic drugs and their effects on cognitive function:
protocol for a systematic review, pairwise, and network
meta-analysis.},
Journal = {Systematic Reviews},
Volume = {12},
Number = {1},
Pages = {54},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1186/s13643-023-02213-5},
Abstract = {BACKGROUND: There is evidence that antipsychotic drugs
differ in their effect on the cognitive symptoms of
schizophrenia. So far, there is no comprehensive systematic
review available that would enable providers and patients to
make informed choices regarding this important aspect of
treatment. With a large number of substances available,
conventional pairwise meta-analyses will not be sufficient
to inform this choice. To fill this gap, we will conduct a
network meta-analysis (NMA), integrating direct and indirect
comparisons from randomized controlled trials (RCTs) to rank
antipsychotics according to their effect on cognitive
functioning. METHODS: In our NMA, we will include RCTs in
patients with schizophrenia or schizophrenia-like psychoses
comparing one antipsychotic agent with another antipsychotic
agent or placebo that measures cognitive function. We will
include studies on patients of every age group, in any phase
of illness (e.g., acute or stable, first episode or chronic
schizophrenia, in- or outpatients) with an intervention time
of at least 3 weeks. The primary outcome will be the
composite score of cognitive functioning, preferentially
measured with the test battery developed by the Measurement
and Treatment Research to Improve Cognition in Schizophrenia
(MATRICS) initiative. The secondary outcomes include the
seven cognitive domains that the composite score is composed
of, as well as functioning and quality of life. Study
selection and data extraction will be conducted by at least
two independent reviewers. We will use the Cochrane Risk of
Bias tool 2 to determine the risk of bias in studies, and we
will evaluate the confidence in the results using Confidence
in Network Meta-Analysis (CINeMA). We will perform NMA using
R (package netmeta). We will conduct subgroup and
sensitivity analyses to explore the heterogeneity and assess
the robustness of our findings. DISCUSSION: This systematic
review and network meta-analysis aims to inform
evidence-based antipsychotic treatment choice for cognitive
deficits in schizophrenia patients by analyzing existing
RCTs on this subject. The results have the potential to
support patients' and physicians' decision-making processes
based on the latest available evidence. SYSTEMATIC REVIEW
REGISTRATION: PROSPERO CRD42022312483.},
Doi = {10.1186/s13643-023-02213-5},
Key = {fds370724}
}
@article{fds370725,
Author = {Kendler, KS and Keefe, RSE and Ohlsson, H and Sundquist, J and Sundquist, K},
Title = {Risk for psychiatric and substance use disorders as a
function of transitions in Sweden's public educational
system: a national study.},
Journal = {Psychol Med},
Pages = {1-8},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1017/S003329172300048X},
Abstract = {BACKGROUND: To clarify, in a national sample, associations
between risk for seven psychiatric and substance use
disorders and five key transitions in Sweden's public
educational system. METHODS: Swedish-born individuals
(1972-1995, N = 1 997 910) were followed through 12-31-2018,
at mean age 34.9. We predicted, from these educational
transitions, risk for major depression (MD),
obsessive-compulsive disorder (OCD), bipolar disorder (BD),
schizophrenia (SZ), anorexia nervosa (AN), alcohol use
disorder (AUD), and drug use disorder (DUD), assessed from
Swedish national registers, by Cox regression, censoring
individuals with onsets ⩽17. We also predicted risk from
the deviation of grades from family-genetic expectations
(deviation 1) and from changes in grades from ages 16 to 19
(deviation 2). RESULTS: We observed four major risk patterns
across transitions in our disorders: (i) MD and BD, (ii) OCD
and SZ, (iii) AUD and DUD, and (iv) AN. Failing early
educational transitions had the greatest impact on risk for
OCD and SZ while for other disorders, not progressing from
basic to upper high school had the largest effect.
Completing vocational v. college-prep upper high school was
strongly associated with risk for AUD and DUD, had little
relation with MD, OCD, BD, and SZ risk, and was protective
for AN. Deviation 1 predicted risk most strongly for SZ, AN,
and MD. Deviation 2 predicted risk most strongly for SZ,
AUD, and DUD. CONCLUSIONS: The pattern of educational
transitions and within family and within person development
deviations are strongly and relatively specifically
associated with future risk for seven psychiatric and
substance-use disorders.},
Doi = {10.1017/S003329172300048X},
Key = {fds370725}
}
@article{fds371563,
Author = {Rekhi, G and Saw, YE and Lim, K and Keefe, RSE and Lee,
J},
Title = {Impact of Cognitive Impairments on Health-Related Quality of
Life in Schizophrenia.},
Journal = {Brain Sciences},
Volume = {13},
Number = {2},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.3390/brainsci13020215},
Abstract = {The impact of cognitive impairments on the health-related
quality of life (HRQoL) in individuals with schizophrenia is
unclear. The aim of this study was to examine the
association between cognitive impairments and HRQoL in
individuals with schizophrenia. A total of 609 individuals
with schizophrenia were assessed on the Positive and
Negative Syndrome Scale (PANSS) and a neurocognitive battery
which comprised of the Wechsler Abbreviated Scale of
Intelligence matrix reasoning, the Benton Judgment of Line
Orientation Test, Continuous Performance Tests-Identical
Pairs, and the Brief Assessment of Cognition in
Schizophrenia. A cognitive factor g was derived from the
neurocognitive battery. EuroQol five-dimensional (EQ-5D-5L)
utility scores were derived from PANSS scores via a
previously validated algorithm and used as a measure of
HRQoL. Hierarchical multiple regression was conducted to
examine the association between cognitive factor g and the
EQ-5D-5L. Cognitive factor g (β = 0.189, t = 4.956, p <
0.001) was found to be significantly associated with
EQ-5D-5L scores. Age (β = -0.258, t = -6.776, p < 0.001),
sex (β = 0.081, t = 2.117, p = 0.035), and being employed
(β = 0.091, t = 2.317, p = 0.021) were also significant
predictors of EQ-5D-5L. Our results add to the extant
literature on the burden cognitive impairments exact in
individuals with schizophrenia. More research is needed to
develop effective interventions for cognitive impairments in
schizophrenia.},
Doi = {10.3390/brainsci13020215},
Key = {fds371563}
}
@article{fds374580,
Author = {Horan, WP and Depp, CA and Hurst, S and Linthicum, J and Vargas, G and Klein, H and Keefe, RSE and Harvey, PD},
Title = {Qualitative Analysis of the Content Validity of the Virtual
Reality Functional Capacity Assessment Tool (VRFCAT) in
Schizophrenia: A Multi-Stakeholder Perspective},
Journal = {Schizophrenia Bulletin Open},
Volume = {4},
Number = {1},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1093/schizbullopen/sgad012},
Abstract = {The US Food and Drug Agency (FDA) requires clinical trials
targeting cognitive impairment associated with schizophrenia
(CIAS) to demonstrate the functional relevance of cognitive
improvements by employing a functional co-primary measure.
Although quantitative evidence supports the suitability of
the Virtual Reality Functional Capacity Assessment Tool
(VRFCAT) for this purpose, FDA guidelines for qualification
of clinical outcome assessments require evidence of content
validity, defined as qualitative evidence that key
stakeholders view the measure as relevant and important. To
collect this important qualitative data, semi-structured
interviews were conducted with outpatients with
schizophrenia (n = 24), caregivers (n = 12), and
professional peer support specialists (n = 12) to elicit
their views about the definition and importance of
functional independence, the importance of the functional
domains assessed by the VRFCAT (meal planning, using
transportation, handling money, shopping), and the relevance
of the VRFCAT tasks to these domains. Qualitative thematic
analyses revealed consistent themes across groups in
defining functional independence, including performing
instrumental self-care, financial, and social tasks; making
decisions autonomously; and not depending on others to carry
out daily activities. There were, however, notable
differences in their views regarding the importance of and
barriers to functional independence. All groups viewed the
VRFCAT as assessing skill domains that are central to
independent functioning and, with some minor differences,
the VRFCAT tasks were viewed as relevant and meaningful
examples of the domains. These qualitative results provide
converging evidence that key stakeholders view the VRFCAT as
a content-valid measure.},
Doi = {10.1093/schizbullopen/sgad012},
Key = {fds374580}
}
%% Kollins, Scott H.
@article{fds369377,
Author = {Fuemmeler, BF and Glasgow, TE and Schechter, JC and Maguire, R and Sheng, Y and Bidopia, T and Barsell, DJ and Ksinan, A and Zhang, J and Lin,
Y and Hoyo, C and Murphy, S and Qin, J and Wang, X and Kollins,
S},
Title = {Prenatal and Childhood Smoke Exposure Associations with
Cognition, Language, and Attention-Deficit/Hyperactivity
Disorder.},
Journal = {J Pediatr},
Volume = {256},
Pages = {77-84.e1},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1016/j.jpeds.2022.11.041},
Abstract = {OBJECTIVE: To assess the relationships of prenatal and
childhood smoke exposure with specific neurodevelopmental
and behavioral problems during early childhood. STUDY
DESIGN: A subsample (n = 386) of mother-child dyads from
the Newborn Epigenetic Study (NEST) prebirth cohort
participated in the study. Cotinine concentrations were used
to objectively measure prenatal and childhood smoke exposure
when youth were aged 3-13 years. Multivariable regression
models were used to estimate associations of prenatal and
childhood cotinine concentrations with performance on the
National Institutes of Health (NIH) Toolbox and
attention-deficit/hyperactivity disorder and behavioral
symptoms, measured using the Behavior Assessment System for
Children, 2nd edition (BASC-2). RESULTS: After adjusting for
confounders, childhood cotinine concentrations were
associated with poorer cognitive performance on tasks
measuring cognitive flexibility (B = -1.29; P = .03),
episodic memory (B = -0.97; P = .02), receptive language
development (B = -0.58; P = .01), and inhibitory control
and attention (B = -1.59; P = .006). Although childhood
cotinine concentration was associated with higher levels of
attention problems (B = 0.83; P = .004) on the BASC-2,
after adjustment for confounders, the association is
nonsignificant. Although associations for maternal cotinine
concentrations were null, an interaction was detected
between prenatal and childhood cotinine concentrations on
the NIH Toolbox Picture Vocabulary Task (P = .02).
CONCLUSIONS: Our findings suggest that childhood tobacco
smoke exposure may lead to poorer attention regulation and
language acquisition, complex visual processing ability, and
attention problems.},
Doi = {10.1016/j.jpeds.2022.11.041},
Key = {fds369377}
}
@article{fds370421,
Author = {Taquet, M and Griffiths, K and Palmer, EOC and Ker, S and Liman, C and Wee,
SN and Kollins, SH and Patel, R},
Title = {Early trajectory of clinical global impression as a
transdiagnostic predictor of psychiatric hospitalisation: a
retrospective cohort study.},
Journal = {Lancet Psychiatry},
Volume = {10},
Number = {5},
Pages = {334-341},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1016/S2215-0366(23)00066-4},
Abstract = {BACKGROUND: Identifying patients most at risk of psychiatric
hospitalisation is crucial to improving service provision
and patient outcomes. Existing predictors focus on specific
clinical scenarios and are not validated with real-world
data, limiting their translational potential. This study
aimed to determine whether early trajectories of Clinical
Global Impression Severity are predictors of 6 month risk of
hospitalisation. METHODS: This retrospective cohort study
used data from the NeuroBlu database, an electronic health
records network from 25 US mental health-care providers.
Patients with an ICD-9 or ICD-10 code of major depressive
disorder, bipolar disorder, generalised anxiety disorder,
post-traumatic stress disorder, schizophrenia or
schizoaffective disorder, ADHD, or personality disorder were
included. Using this cohort, we assessed whether clinical
severity and instability (operationalised using Clinical
Global Impression Severity measurements) during a 2-month
period were predictors of psychiatric hospitalisation within
the next 6 months. FINDINGS: 36 914 patients were included
(mean age 29·7 years [SD 17·5]; 21 156 [57·3%] female,
15 748 [42·7%] male; 20 559 [55·7%] White, 4842
[13·1%] Black or African American, 286 [0·8%] Native
Hawaiian or other Pacific Islander, 300 [0·8%] Asian, 139
[0·4%] American Indian or Alaska Native, 524 (1·4%) other
or mixed race, and 10 264 [27·8%] of unknown race).
Clinical severity and instability were independent
predictors of risk of hospitalisation (adjusted hazard ratio
[HR] 1·09, 95% CI 1·07-1·10 for every SD increase in
instability; 1·11, 1·09-1·12 for every SD increase in
severity; p<0·0001 for both). These associations were
consistent across all diagnoses, age groups, and in both
males and females, as well as in several robustness
analyses, including when clinical severity and clinical
instability were based on the Patient Health Questionnaire-9
rather than Clinical Global Impression Severity
measurements. Patients in the top half of the cohort for
both clinical severity and instability were at an increased
risk of hospitalisation compared with those in the bottom
half along both dimensions (HR 1·45, 95% CI 1·39-1·52;
p<0·0001). INTERPRETATION: Clinical instability and
severity are independent predictors of future risk of
hospitalisation, across diagnoses, age groups, and in both
males and females. These findings could help clinicians make
prognoses and screen patients who are most likely to benefit
from intensive interventions, as well as help health-care
providers plan service provisions by adding additional
detail to risk prediction tools that incorporate other risk
factors. FUNDING: National Institute for Health and Care
Research, National Institute for Health and Care Research
Oxford Health Biomedical Research Centre, Medical Research
Council, Academy of Medical Sciences, and
Holmusk.},
Doi = {10.1016/S2215-0366(23)00066-4},
Key = {fds370421}
}
@misc{fds370391,
Author = {Bidopia, T and Engelhard, MM and Kollins, SH and Lunsford-Avery,
JR},
Title = {Screen media technology and ADHD in children and
adolescents: Potential perils and emerging
opportunities},
Volume = {3},
Pages = {260-274},
Booktitle = {Encyclopedia of Child and Adolescent Health, First
Edition},
Year = {2023},
Month = {January},
ISBN = {9780128188729},
url = {http://dx.doi.org/10.1016/B978-0-12-818872-9.00126-6},
Abstract = {Screen media technology (SMT) use has become increasingly
prevalent among youth, and is associated with a variety of
negative outcomes, including poor sleep and impairments in
several domains of cognitive functioning, including
task-switching, attention, working memory, and response
inhibition. Youth with ADHD may be particularly vulnerable
to the hazards of SMT use and engage in problematic
screentime behaviors at disproportionate rates. SMT may
result in negative outcomes for individuals with ADHD via
several processes, including: (a) screen characteristics,
nighttime use, and interference with sleep, (b) media
multitasking, (c) device notifications, (d) media content,
and (e) compulsive SMT use. Despite the harmful effects of
SMT use, digital therapeutics, such as serious game
interventions, SMS interventions, and smartphone
applications, have demonstrated promise in improving ADHD
symptoms and enhancing medication treatment adherence in
youth with ADHD. Several unknowns currently exist in
relation to the effects of SMT use in children and
adolescents with ADHD. Research should focus on
disentangling the directionality and strength of the
relationship between SMT use and ADHD-related symptoms,
along with individual-level factors related to harmful SMT
use, such as sociodemographic background. Further research
using longitudinal designs and objective measurements of SMT
use is needed to better understand the effect of
screen-based behaviors on the mental and physical wellbeing
of youth with ADHD and to pinpoint potential intervention
targets. Parental mediation strategies, such as
autonomy-supportive mediation, may be an effective strategy
for mitigating the hazardous effects of SMT use in this
population.},
Doi = {10.1016/B978-0-12-818872-9.00126-6},
Key = {fds370391}
}
@article{fds365163,
Author = {Vosburg, SK and Faraone, SV and Riley, E and Whitaker, T and Kardish, J and Baker, D and Kollins, SH and Rush, CR},
Title = {Intranasal Use of Prescription Stimulants Among Adults Aged
18 to 30: Results From A Crowdsourcing Platform.},
Journal = {J Atten Disord},
Volume = {27},
Number = {1},
Pages = {14-25},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1177/10870547221112948},
Abstract = {OBJECTIVE: Few studies of prescription stimulant non-oral,
non-medical use (NMU) (defined by use not as prescribed)
have been conducted in adults beyond the college population.
The purpose of this study was to characterize prescription
stimulant non-oral use, specifically intranasal (IN) use
(snorting) in young adults. METHOD: Amazon's MTurk platform
was used to recruit participants for an online survey. Data
were collected from March to April 2020. RESULTS: Thirty-two
percent (n = 157) of survey respondents (N = 975), aged 18
to 30, reported IN prescription stimulant use (average of
32.1 episodes of lifetime IN use). Adderall was the
most-reported prescription stimulant used intranasally
(89.2%). Most IN users (82%; n = 68) reported spending no
more than 5 minutes tampering with prescription stimulants.
Intranasal users said they would take the medication orally
if unable to tamper or manipulate medication for IN use.
CONCLUSION: These data help quantify a complex public health
issue of ongoing IN use of prescription stimulants and
suggest a potential role for manipulation-deterrent
medications.},
Doi = {10.1177/10870547221112948},
Key = {fds365163}
}
%% Kushnir, Tamar
@article{fds375236,
Author = {Finiasz, Z and Gelman, SA and Kushnir, T},
Title = {Testimony and observation of statistical evidence interact
in adults' and children's category-based
induction.},
Journal = {Cognition},
Volume = {244},
Pages = {105707},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1016/j.cognition.2023.105707},
Abstract = {Hearing generic or other kind-relevant claims can influence
the use of information from direct observations in category
learning. In the current study, we ask how both adults and
children integrate their observations with testimony when
learning about the causal property of a novel category.
Participants were randomly assigned to hear one of four
types of testimony: generic, quantified "all", specific, or
only labels. In Study 1, adults (N = 1249) then observed
that some proportion of objects (10%-100%) possessed a
causal property. In Study 2, children (N = 123,
M<sub>age</sub> = 5.06 years, SD = 0.61 years, range
4.01-5.99 years) observed a sample where 30% of the objects
had the causal property. Generic and quantified "all" claims
led both adults and children to generalize the causal
property beyond what was observed. Adults and children
diverged, however, in their overall trust in testimony that
could be verified by observations: adults were more
skeptical of inaccurate quantified claims, whereas children
were more accepting. Additional memory probes suggest that
children's trust in unverified claims may have been due to
misremembering what they saw in favor of what they heard.
The current findings demonstrate that both child and adult
learners integrate information from both sources, offering
insights into the mechanisms by which language frames
first-hand experience.},
Doi = {10.1016/j.cognition.2023.105707},
Key = {fds375236}
}
@article{fds372785,
Author = {Katz, T and Kushnir, T and Tomasello, M},
Title = {Children are eager to take credit for prosocial acts, and
cost affects this tendency.},
Journal = {Journal of experimental child psychology},
Volume = {237},
Pages = {105764},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.jecp.2023.105764},
Abstract = {We report two experiments on children's tendency to enhance
their reputations through communicative acts. In the
experiments, 4-year-olds (N = 120) had the opportunity to
inform a social partner that they had helped him in his
absence. In a first experiment, we pitted a prosocial act
("Let's help clean up for Doggie!") against an instrumental
act ("Let's move these out of our way"). Children in the
prosocial condition were quicker to inform their partner of
the act and more likely to protest when another individual
was given credit for it. In a second experiment, we
replicated the prosocial condition but with a new
manipulation: high-cost versus low-cost helping. We
manipulated both the language surrounding cost (i.e., "This
will be pretty tough to clean up" vs. "It will be really
easy to clean this up") and how difficult the task itself
was. As predicted, children in the high-cost condition were
quicker to inform their partner of the act and more likely
to take back credit for it. These results suggest that even
4-year-old children make active attempts to elicit positive
reputational judgments for their prosocial acts, with cost
as a moderating factor.},
Doi = {10.1016/j.jecp.2023.105764},
Key = {fds372785}
}
@article{fds376647,
Author = {Weisman, K and Ghossainy, ME and Williams, AJ and Payir, A and Lesage,
KA and Reyes-Jaquez, B and Amin, TG and Anggoro, FK and Burdett, ERR and Chen, EE and Coetzee, L and Coley, JD and Dahl, A and Dautel, JB and Davis,
HE and Davis, EL and Diesendruck, G and Evans, D and Feeney, A and Gurven,
M and Jee, BD and Kramer, HJ and Kushnir, T and Kyriakopoulou, N and McAuliffe, K and McLaughlin, A and Nichols, S and Nicolopoulou, A and Rockers, PC and Shneidman, L and Skopeliti, I and Srinivasan, M and Tarullo, AR and Taylor, LK and Yu, Y and Yucel, M and Zhao, X and Corriveau, KH and Richert, RA and Developing Belief
Network},
Title = {The development and diversity of religious cognition and
behavior: Protocol for Wave 1 data collection with children
and parents by the Developing Belief Network.},
Journal = {PloS one},
Volume = {19},
Number = {3},
Pages = {e0292755},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1371/journal.pone.0292755},
Abstract = {The Developing Belief Network is a consortium of researchers
studying human development in diverse social-cultural
settings, with a focus on the interplay between general
cognitive development and culturally specific processes of
socialization and cultural transmission in early and middle
childhood. The current manuscript describes the study
protocol for the network's first wave of data collection,
which aims to explore the development and diversity of
religious cognition and behavior. This work is guided by
three key research questions: (1) How do children represent
and reason about religious and supernatural agents? (2) How
do children represent and reason about religion as an aspect
of social identity? (3) How are religious and supernatural
beliefs transmitted within and between generations? The
protocol is designed to address these questions via a set of
nine tasks for children between the ages of 4 and 10 years,
a comprehensive survey completed by their
parents/caregivers, and a task designed to elicit
conversations between children and caregivers. This study is
being conducted in 39 distinct cultural-religious groups (to
date), spanning 17 countries and 13 languages. In this
manuscript, we provide detailed descriptions of all elements
of this study protocol, give a brief overview of the ways in
which this protocol has been adapted for use in diverse
religious communities, and present the final,
English-language study materials for 6 of the 39
cultural-religious groups who are currently being recruited
for this study: Protestant Americans, Catholic Americans,
American members of the Church of Jesus Christ of Latter-day
Saints, Jewish Americans, Muslim Americans, and religiously
unaffiliated Americans.},
Doi = {10.1371/journal.pone.0292755},
Key = {fds376647}
}
@article{fds372600,
Author = {Kushnir, T and Katz, T and Stegall, J},
Title = {A Review of “Becoming Human”},
Journal = {Journal of Cognition and Development},
Volume = {24},
Number = {4},
Pages = {620-622},
Publisher = {Informa UK Limited},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1080/15248372.2023.2226207},
Doi = {10.1080/15248372.2023.2226207},
Key = {fds372600}
}
@article{fds369144,
Author = {Heck, IA and Kushnir, T and Kinzler, KD},
Title = {Building representations of the social world: Children
extract patterns from social choices to reason about
multi-group hierarchies.},
Journal = {Developmental science},
Volume = {26},
Number = {4},
Pages = {e13366},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1111/desc.13366},
Abstract = {How do children learn about the structure of the social
world? We tested whether children would extract patterns
from an agent's social choices to make inferences about
multiple groups' relative social standing. In Experiment 1,
4- to 6-year-old children (N = 36; tested in Central New
York) saw an agent and three groups (Group-A, Group-B, and
Group-C) and observed the agent choose between pairs of
individuals from different groups. Across pairwise
selections, a pattern emerged: The agent chose individuals
from Group-A > Group-B > Group-C. Children tracked the
agent's choices to predict that Group-A was "most-preferred"
and the "leader" and that Group-C was "least-preferred" and
the "helper." In Experiments 2 and 3, we examined children's
reasoning about a more complex pattern involving four groups
and tested a wider age range. In Experiment 2, 5- to
10-year-old children (N = 98; tested in Central New York)
used the agent's pattern of pairwise choices to infer that
the agent liked Group-A > Group-B > Group-C > Group-D
and to make predictions about which groups were likely to be
"leaders" and "helpers." In Experiment 3, we found evidence
for social specificity in children's reasoning: 5- to
10-year-old children (N = 96; from 26 US States) made
inferences about groups' relative social but not physical
power from the agent's pattern of affiliative choices across
the four groups. These findings showcase a mechanism through
which children may learn about societal-level hierarchies
through the patterns they observe over time in people's
group-based social choices. RESEARCH HIGHLIGHTS: Children in
our sample extracted patterns from an agent's positive
social choices between multiple groups to reason about
groups' relative social standing. Children used the pattern
of an agent's positive social choices to guide their
reasoning about which groups were likely to be "leaders" and
"helpers" in a fictional town. The pattern that emerged in
an agent's choices of friends shaped children's thinking
about groups' relative social but not physical power.
Children tracked social choices to reason about group-based
hierarchies at the individual level (which groups an agent
prefers) and societal level (which groups are
privileged).},
Doi = {10.1111/desc.13366},
Key = {fds369144}
}
@article{fds370243,
Author = {Flanagan, T and Wong, G and Kushnir, T},
Title = {The minds of machines: Children's beliefs about the
experiences, thoughts, and morals of familiar interactive
technologies.},
Journal = {Developmental psychology},
Volume = {59},
Number = {6},
Pages = {1017-1031},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1037/dev0001524},
Abstract = {Children are developing alongside interactive technologies
that can move, talk, and act like agents, but it is unclear
if children's beliefs about the agency of these household
technologies are similar to their beliefs about advanced,
humanoid robots used in lab research. This study
investigated 4-11-year-old children's (<i>N</i> = 127,
<i>M</i><sub>age</sub> = 7.50, <i>SD</i><sub>age</sub> =
2.27, 53% females, 75% White; from the Northeastern United
States) beliefs about the mental, physical, emotional, and
moral features of two familiar technologies (Amazon Alexa
and Roomba) in comparison to their beliefs about a humanoid
robot (Nao). Children's beliefs about the agency of these
technologies were organized into three distinct
clusters-having experiences, having minds, and deserving
moral treatment. Children endorsed some agent-like features
for each technology type, but the extent to which they did
so declined with age. Furthermore, children's judgment of
the technologies' freedom to "act otherwise" in moral
scenarios changed with age, suggesting a development shift
in children's understanding of technologies' limitations.
Importantly, there were systematic differences between
Alexa, Roomba, and Nao, that correspond to the unique
characteristics of each. Together these findings suggest
that children's intuitive theories of agency are informed by
an increasingly technological world. (PsycInfo Database
Record (c) 2023 APA, all rights reserved).},
Doi = {10.1037/dev0001524},
Key = {fds370243}
}
@article{fds369077,
Author = {Partington, S and Nichols, S and Kushnir, T},
Title = {Rational learners and parochial norms.},
Journal = {Cognition},
Volume = {233},
Pages = {105366},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1016/j.cognition.2022.105366},
Abstract = {Parochial norms are narrow in social scope, meaning they
apply to certain groups but not to others. Accounts of norm
acquisition typically invoke tribal biases: from an early
age, people assume a group's behavioral regularities are
prescribed and bounded by mere group membership. However,
another possibility is rational learning: given the
available evidence, people infer the social scope of norms
in statistically appropriate ways. With this paper, we
introduce a rational learning account of parochial norm
acquisition and test a unique prediction that it makes. In
one study with adults (N = 480) and one study with
children ages 5- to 8-years-old (N = 120), participants
viewed violations of a novel rule sampled from one of two
unfamiliar social groups. We found that adults judgments of
social scope - whether the rule applied only to the sampled
group (parochial scope), or other groups (inclusive scope) -
were appropriately sensitive to the relevant features of
their statistical evidence (Study 1). In children (Study 2)
we found an age difference: 7- to 8-year-olds used
statistical evidence to infer that norms were parochial or
inclusive, whereas 5- to 6-year olds were overall inclusive
regardless of statistical evidence. A Bayesian analysis
shows a possible inclusivity bias: adults and children
inferred inclusive rules more frequently than predicted by a
naïve Bayesian model with unbiased priors. This work
highlights that tribalist biases in social cognition are not
necessary to explain the acquisition of parochial
norms.},
Doi = {10.1016/j.cognition.2022.105366},
Key = {fds369077}
}
@article{fds363275,
Author = {Zhao, X and Kushnir, T},
Title = {When it's not easy to do the right thing: Developmental
changes in understanding cost drive evaluations of moral
praiseworthiness.},
Journal = {Developmental science},
Volume = {26},
Number = {1},
Pages = {e13257},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1111/desc.13257},
Abstract = {Recent work identified a shift in judgments of moral
praiseworthiness that occurs late in development: adults
recognize the virtue of moral actions that involve resolving
an inner conflict between moral desires and selfish desires.
Children, in contrast, praise agents who do the right thing
in the absence of inner conflict. This finding stands in
contrast with other work showing that children incorporate
notions of cost and effort into their social reasoning.
Using a modified version of Starmans and Bloom's (2016)
vignettes, we show that understanding the virtue of costly
moral action precedes understanding the virtue of resolving
inner conflict. In two studies (N = 192 children,
range = 4.00-9.95 years; and N = 193 adults), we
contrasted a character who paid a personal cost
(psychological in Study 1, physical in Study 2) to perform a
moral action with another who acted morally without paying a
cost. We found a developmental progression; 8- and
9-year-old children and adults recognized the
praiseworthiness of moral actions that are psychologically
or physically costly. Six- and 7-year-old children only
recognized the praiseworthiness of moral actions that are
physically costly, but not actions that are psychologically
costly. Moreover, neither adults nor children inferred that
paying a cost to act morally required having a moral desire
or resolving inner conflict. These results suggest that both
adults and children conceptualize obligation as a direct
motivational force on actions. They further suggest that
costly choice-a hallmark of moral agency-is implicated in
judgments of praiseworthiness early in development.},
Doi = {10.1111/desc.13257},
Key = {fds363275}
}
@article{fds372714,
Author = {Carpenter, E and Siegel, A and Urquiola, S and Liu, J and Kushnir,
T},
Title = {Being me in times of change: Young children's reflections on
their lives during the COVID-19 pandemic},
Journal = {Children and Society},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1111/chso.12790},
Abstract = {Research from the perspective of parents, educators and
mental health professionals has documented the negative
impacts of pandemic isolation on children, but few studies
have sought children's own perspectives on this difficult
year. The current study aims to provide a first-person
perspective on children's psychological health by asking
children directly about their experiences of isolating at
home. We interviewed 28 seven- to eleven-year-olds in early
days of lockdowns with follow-ups 6 months later. Children
answered questions about family, school, friendships and
feelings about the changes in their lives during lockdown.
Children's reflections showed resilience, adaptability,
positive appraisals and an ability to maintain meaningful
social connections. This data underscores the value of
including children's narratives to better understand the
pandemic's lasting effects on their lives.},
Doi = {10.1111/chso.12790},
Key = {fds372714}
}
%% LaBar, Kevin S.
@article{fds375524,
Author = {Neacsiu, AD and Beynel, L and Gerlus, N and LaBar, KS and Bukhari-Parlakturk, N and Rosenthal, MZ},
Title = {An experimental examination of neurostimulation and
cognitive restructuring as potential components for
Misophonia interventions.},
Journal = {J Affect Disord},
Volume = {350},
Pages = {274-285},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1016/j.jad.2024.01.120},
Abstract = {Misophonia is a disorder of decreased tolerance to certain
aversive, repetitive common sounds, or to stimuli associated
with these sounds. Two matched groups of adults (29
participants with misophonia and 30 clinical controls with
high emotion dysregulation) received inhibitory
neurostimulation (1 Hz) over a personalized medial
prefrontal cortex (mPFC) target functionally connected to
the left insula; excitatory neurostimulation (10 Hz) over a
personalized dorsolateral PFC (dlPFC) target; and sham
stimulation over either target. Stimulations were applied
while participants were either listening or cognitively
downregulating emotions associated with personalized
aversive, misophonic, or neutral sounds. Subjective units of
distress (SUDS) and psychophysiological measurements (e.g.,
skin conductance response [SCR] and level [SCL]) were
collected. Compared to controls, participants with
misophonia reported higher distress (∆SUDS = 1.91-1.93,
ps < 0.001) when listening to and when downregulating
misophonic distress. Both types of neurostimulation reduced
distress significantly more than sham, with excitatory rTMS
providing the most benefit (Cohen's dSUDS = 0.53;
dSCL = 0.14). Excitatory rTMS also enhanced the regulation
of emotions associated with misophonic sounds in both groups
when measured by SUDS (dcontrol = 1.28;
dMisophonia = 0.94), and in the misophonia group alone
when measured with SCL (d = 0.20). Both types of
neurostimulation were well tolerated. Engaging in cognitive
restructuring enhanced with high-frequency neurostimulation
led to the lowest misophonic distress, highlighting the best
path forward for misophonia interventions.},
Doi = {10.1016/j.jad.2024.01.120},
Key = {fds375524}
}
@article{fds374231,
Author = {Reeck, C and LaBar, KS},
Title = {Retrieval-induced forgetting of emotional
memories.},
Journal = {Cognition & emotion},
Volume = {38},
Number = {1},
Pages = {131-147},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1080/02699931.2023.2279156},
Abstract = {Long-term memory manages its contents to facilitate adaptive
behaviour, amplifying representations of information
relevant to current goals and expediting forgetting of
information that competes with relevant memory traces. Both
mnemonic selection and inhibition maintain congruence
between the contents of long-term memory and an organism's
priorities. However, the capacity of these processes to
modulate affective mnemonic representations remains
ambiguous. Three empirical experiments investigated the
consequences of mnemonic selection and inhibition on
affectively charged and neutral mnemonic representations
using an adapted retrieval practice paradigm. Participants
encoded neutral cue words and affectively negative or
neutral associates and then selectively retrieved a subset
of these associates multiple times. The consequences of
selection and inhibitory processes engaged during selective
retrieval were evaluated on a final memory test in which
recall for all studied associates was probed. Analyses of
memory recall indicated that both affectively neutral and
negative mnemonic representations experienced similar levels
of enhancement and impairment following selective retrieval,
demonstrating the susceptibility of affectively salient
memories to these mnemonic processes. These findings
indicate that although affective memories may be more
strongly encoded in memory, they remain amenable to
inhibition and flexibly adaptable to the evolving needs of
the organism.},
Doi = {10.1080/02699931.2023.2279156},
Key = {fds374231}
}
@article{fds367262,
Author = {Faul, L and LaBar, KS},
Title = {Mood-congruent memory revisited.},
Journal = {Psychological review},
Volume = {130},
Number = {6},
Pages = {1421-1456},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1037/rev0000394},
Abstract = {Affective experiences are commonly represented by either
transient emotional reactions to discrete events or longer
term, sustained mood states that are characterized by a more
diffuse and global nature. While both have considerable
influence in shaping memory, their interaction can produce
mood-congruent memory (MCM), a psychological phenomenon
where emotional memory is biased toward content affectively
congruent with a past or current mood. The study of MCM has
direct implications for understanding how memory biases form
in daily life, as well as debilitating negative memory
schemas that contribute to mood disorders such as
depression. To elucidate the factors that influence the
presence and strength of MCM, here we systematically review
the literature for studies that assessed MCM by inducing
mood in healthy participants. We observe that MCM is often
reported as enhanced accuracy for previously encoded
mood-congruent content or preferential recall for
mood-congruent autobiographical events, but may also
manifest as false memory for mood-congruent lures. We
discuss the relevant conditions that shape these effects, as
well as instances of mood-incongruent recall that facilitate
mood repair. Further, we provide guiding methodological and
theoretical considerations, emphasizing the limited
neuroimaging research in this area and the need for a
renewed focus on memory consolidation. Accordingly, we
propose a theoretical framework for studying the neural
basis of MCM based on the neurobiological underpinnings of
mood and emotion. In doing so, we review evidence for
associative network models of spreading activation, while
also considering alternative models informed by the
cognitive neuroscience literature of emotional memory bias.
(PsycInfo Database Record (c) 2024 APA, all rights
reserved).},
Doi = {10.1037/rev0000394},
Key = {fds367262}
}
@article{fds367771,
Author = {Faul, L and Baumann, MG and LaBar, KS},
Title = {The representation of emotional experience from imagined
scenarios.},
Journal = {Emotion (Washington, D.C.)},
Volume = {23},
Number = {6},
Pages = {1670-1686},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1037/emo0001192},
Abstract = {One of the key unresolved issues in affective science is
understanding how the subjective experience of emotion is
structured. Semantic space theory has shed new light on this
debate by applying computational methods to high-dimensional
data sets containing self-report ratings of emotional
responses to visual and auditory stimuli. We extend this
approach here to the emotional experience induced by
imagined scenarios. Participants chose at least one emotion
category label among 34 options or provided ratings on 14
affective dimensions while imagining two-sentence
hypothetical scenarios. A total of 883 scenarios were rated
by at least 11 different raters on categorical or
dimensional qualities, with a total of 796 participants
contributing to the final normed stimulus set. Principal
component analysis reduced the categorical data to 24
distinct varieties of reported experience, while cluster
visualization indicated a blended, rather than discrete,
distribution of the corresponding emotion space. Canonical
correlation analysis between the categorical and dimensional
data further indicated that category endorsement accounted
for more variance in dimensional ratings than vice versa,
with 10 canonical variates unifying change in category
loadings with affective dimensions such as valence, arousal,
safety, and commitment. These findings indicate that
self-reported emotional responses to imaginative experiences
exhibit a clustered structure, although clusters are
separated by fuzzy boundaries, and variable dimensional
properties associate with smooth gradients of change in
categorical judgments. The resultant structure supports the
tenets of semantic space theory and demonstrates some
consistency with prior work using different emotional
stimuli. (PsycInfo Database Record (c) 2023 APA, all rights
reserved).},
Doi = {10.1037/emo0001192},
Key = {fds367771}
}
@article{fds370956,
Author = {Faul, L and Rothrock, JM and LaBar, KS},
Title = {Self-Relevance Moderates the Relationship between Depressive
Symptoms and Corrugator Activity during the Imagination of
Personal Episodic Events.},
Journal = {Brain sciences},
Volume = {13},
Number = {6},
Pages = {843},
Publisher = {MDPI AG},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.3390/brainsci13060843},
Abstract = {Accumulating evidence suggests depression is associated with
blunted reactivity to positive and negative stimuli, known
as emotion context insensitivity (ECI). However, ECI is not
consistently observed in the literature, suggesting
moderators that influence its presence. We propose
self-relevance as one such moderator, with ECI most apparent
when self-relevance is low. We examined this proposal by
measuring self-report and facial electromyography (EMG) from
the corrugator muscle while participants (n = 81) imagined
hypothetical scenarios with varying self-relevance and
recalled autobiographical memories. Increased depressive
symptoms on the Center for Epidemiologic Studies Depression
Scale were associated with less differentiated arousal and
self-relevance ratings between happy, neutral, and sad
scenarios. EMG analyses further revealed that individuals
with high depressive symptoms exhibited blunted corrugator
reactivity (reduced differentiation) for sad, neutral, and
happy scenarios with low self-relevance, while corrugator
reactivity remained sensitive to valence for highly
self-relevant scenarios. By comparison, in individuals with
low depressive symptoms, corrugator activity differentiated
valence regardless of stimulus self-relevance. Supporting a
role for self-relevance in shaping ECI, we observed no
depression-related differences in emotional reactivity when
participants recalled highly self-relevant happy or sad
autobiographical memories. Our findings suggest ECI is
primarily associated with blunted reactivity towards
material deemed low in self-relevance.},
Doi = {10.3390/brainsci13060843},
Key = {fds370956}
}
@article{fds371648,
Author = {LaBar, KS},
Title = {Neuroimaging of Fear Extinction.},
Journal = {Current topics in behavioral neurosciences},
Volume = {64},
Pages = {79-101},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1007/7854_2023_429},
Abstract = {Extinguishing fear and defensive responses to environmental
threats when they are no longer warranted is a critical
learning ability that can promote healthy self-regulation
and, ultimately, reduce susceptibility to or maintenance of
affective-, trauma-, stressor-,and anxiety-related
disorders. Neuroimaging tools provide an important means to
uncover the neural mechanisms of effective extinction
learning that, in turn, can abate the return of fear. Here I
review the promises and pitfalls of functional neuroimaging
as a method to investigate fear extinction circuitry in the
healthy human brain. I discuss the extent to which
neuroimaging has validated the core circuits implicated in
rodent models and has expanded the scope of the brain
regions implicated in extinction processes. Finally, I
present new advances made possible by multivariate data
analysis tools that yield more refined insights into the
brain-behavior relationships involved.},
Doi = {10.1007/7854_2023_429},
Key = {fds371648}
}
@article{fds373632,
Author = {Faul, L and Baumann, MG and LaBar, KS},
Title = {The Representation of Emotional Experience from Imagined
Scenarios},
Journal = {AFFECTIVE SCIENCE},
Volume = {4},
Number = {1},
Year = {2023},
Key = {fds373632}
}
%% Larrick, Richard P.
@article{fds373576,
Author = {Fath, S and Larrick, RP and Soll, JB},
Title = {Encouraging self-blinding in hiring},
Journal = {Behavioral Science and Policy},
Volume = {9},
Number = {1},
Pages = {45-57},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1177/23794607231192721},
Abstract = {One strategy for minimizing bias in hiring is
blinding—purposefully limiting the information used when
screening applicants to that which is directly relevant to
the job and does not elicit bias based on race, gender, age,
or other irrelevant characteristics. Blinding policies
remain rare, however. An alternative to blinding policies is
self-blinding, in which people performing hiring-related
evaluations blind themselves to biasing information about
applicants. Using a mock-hiring task, we tested ways to
encourage self-blinding that take into consideration three
variables likely to affect whether people self-blind:
default effects on choices, people’s inability to assess
their susceptibility to bias, and people’s tendency not to
recognize the full range of information that can elicit that
bias. Participants with hiring experience chose to receive
or be blind to various pieces of information about
applicants, some of which were potentially biasing. They
selected potentially biasing information less often when
asked to specify the applicant information they wanted to
receive than when asked to specify the information they did
not want to receive, when prescribing selections for other
people than when making the selections for themselves, and
when the information was obviously biasing than when it was
less obviously so. On the basis of these findings, we
propose a multipronged strategy that human resources leaders
could use to enable and encourage hiring managers to
self-blind when screening job applicants.},
Doi = {10.1177/23794607231192721},
Key = {fds373576}
}
%% Levin, Edward D.
@article{fds375370,
Author = {Hawkey, AB and Shekey, N and Dean, C and Asrat, H and Koburov, R and Holloway, ZR and Kullman, SW and Levin, ED},
Title = {Developmental exposure to pesticides that disrupt retinoic
acid signaling causes persistent retinoid and behavioral
dysfunction in zebrafish.},
Journal = {Toxicol Sci},
Volume = {198},
Number = {2},
Pages = {246-259},
Publisher = {Oxford University Press (OUP)},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1093/toxsci/kfae001},
Abstract = {Early developmental exposure to environmental toxicants may
play a role in the risk for developing autism. A variety of
pesticides have direct effects on retinoic acid (RA)
signaling and as RA signaling has important roles in
neurodevelopment, such compounds may cause developmental
neurotoxicity through an overlapping adverse outcome
pathway. It is hypothesized that a pesticide's embryonic
effects on retinoid function may correspond with
neurobehavioral disruption later in development. In the
current studies, we determined the effects of RA-acting
pesticides on neurobehavioral development in zebrafish.
Buprofezin and imazalil caused generalized hypoactivity in
the larval motility test, whereas chlorothalonil and
endosulfan I led to selective hypoactivity and
hyperactivity, respectively. With buprofezin,
chlorothalonil, and imazalil, hypoactivity and/or novel
anxiety-like behaviors persisted in adulthood and buprofezin
additionally decreased social attraction responses in
adulthood. Endosulfan I did not produce significant adult
behavioral effects. Using qPCR analyses of adult brain
tissue, we observed treatment-induced alterations in RA
synthesis or catabolic genes, indicating persistent changes
in RA homeostasis. These changes were compound-specific,
with respect to expression directionality, and potential
patterns of homeostatic disruption. Results suggest the
likely persistence of disruptions in RA signaling well into
adulthood and may represent compensatory mechanisms
following early life stage exposures. This study
demonstrates that early developmental exposure to
environmental toxicants that interfere with RA signaling
causes short as well as long-term behavioral disruption in a
well-established zebrafish behavioral model and expand upon
the meaning of the RA adverse outcome pathway, indicating
that observed effects likely correspond with the nature of
underlying homeostatic effects.},
Doi = {10.1093/toxsci/kfae001},
Key = {fds375370}
}
@article{fds376105,
Author = {Marchese, MJ and Zhu, T and Hawkey, AB and Wang, K and Yuan, E and Wen, J and Be, SE and Levin, ED and Feng, L},
Title = {Prenatal and perinatal exposure to Per- and polyfluoroalkyl
substances (PFAS)-contaminated drinking water impacts
offspring neurobehavior and development.},
Journal = {Sci Total Environ},
Volume = {917},
Pages = {170459},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1016/j.scitotenv.2024.170459},
Abstract = {Per- and polyfluoroalkyl substances (PFAS) are persistent
organic pollutants ubiquitous in the environment and humans.
In-utero PFAS exposure is associated with numerous adverse
health impacts. However, little is known about how prenatal
PFAS mixture exposure affects offspring's neurobehavioral
function. This study aims to determine the causal
relationship between in-utero PFAS mixture exposure and
neurobehavioral changes in Sprague-Dawley rat offspring.
Dams were exposed via drinking water to the vehicle
(control), an environmentally relevant PFAS mixture, or a
high-dose PFAS mixture. The environmentally relevant mixture
was formulated to resemble measured tap water levels in
Pittsboro, NC, USA (10 PFAS compounds; sum PFAS
=758.6 ng/L). The high-dose PFAS load was 3.8 mg/L
(5000×), within the range of exposures in the experimental
literature. Exposure occurred seven days before mating until
birth. Following exposure to PFAS-laden water or the vehicle
during fetal development, neurobehavioral toxicity was
assessed in male and female offspring with a battery of
motor, cognitive, and affective function tests as juveniles,
adolescents, and adults. Just before weaning, the
environmentally relevant exposure group had smaller
anogenital distances compared to the vehicle and high-dose
groups on day 17, and males in the environmentally relevant
exposure group demonstrated lower weights than the high-dose
group on day 21 (p < 0.05). Reflex development delays were
seen in negative geotaxis acquisition for both exposure
groups compared to vehicle-exposed controls (p = 0.009).
Our post-weaning behavioral measures of anxiety, depression,
and memory were not found to be affected by maternal PFAS
exposure. In adolescence (week five) and adulthood (week
eight), the high PFAS dose significantly attenuated typical
sex differences in locomotor activity. Maternal exposure to
an environmentally relevant PFAS mixture produced
developmental delays in the domains of pup weight,
anogenital distance, and reflex acquisition for rat
offspring. The high-dose PFAS exposure significantly
decreased typical sex differences in locomotor
activity.},
Doi = {10.1016/j.scitotenv.2024.170459},
Key = {fds376105}
}
@article{fds374240,
Author = {Natarajan, S and Abass, G and Kim, L and Wells, C and Rezvani, AH and Levin, ED},
Title = {Acute and chronic glutamate NMDA antagonist treatment
attenuates dopamine D1 antagonist-induced reduction of
nicotine self-administration in female rats.},
Journal = {Pharmacol Biochem Behav},
Volume = {234},
Pages = {173678},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.pbb.2023.173678},
Abstract = {Multiple interacting neural systems are involved in
sustaining nicotine reinforcement. We and others have shown
that dopamine D1 receptors and glutamate NMDA receptors both
play important roles in nicotine reinforcement. Blockade of
D1 receptors with the antagonist SCH-23390 (0.02 mg/kg)
both acutely and chronically significantly decreased
nicotine self-administration in rats. Blockade of NMDA
receptors (10 mg/kg) acutely with memantine significantly
increased nicotine self-administration, but chronic blockade
of NMDA receptors with memantine significantly decreased
nicotine self-administration. The current study examined the
interactions of acute and chronic administration of
SCH-23390 and memantine on nicotine self-administration in
female rats. Replicating earlier studies, acute and chronic
SCH-23390 significantly decreased nicotine
self-administration and memantine had a biphasic effect with
acute administration increasing nicotine self-administration
and chronic memantine showed a non-significant trend toward
decreasing it. However, chronic interaction study showed
that memantine significantly attenuated the decrease in
nicotine self-administration caused by chronic SCH-23390.
These studies provide important information that memantine
attenuates the efficacy of D1 antagonist SCH 23390 in
reducing nicotine-self-administration. These two drugs do
not appear to have mutually potentiating effects to aid
tobacco cessation.},
Doi = {10.1016/j.pbb.2023.173678},
Key = {fds374240}
}
@article{fds376269,
Author = {Stickler, A and Hawkey, AB and Gondal, A and Natarajan, S and Mead, M and Levin, ED},
Title = {Embryonic exposures to cadmium and PAHs cause long-term and
interacting neurobehavioral effects in zebrafish.},
Journal = {Neurotoxicol Teratol},
Volume = {102},
Pages = {107339},
Year = {2024},
url = {http://dx.doi.org/10.1016/j.ntt.2024.107339},
Abstract = {Developmental exposure to either polycyclic aromatic
hydrocarbons (PAHs) or heavy metals has been shown to cause
persisting and overlapping neurobehavioral effects in animal
models. However, interactions between these compounds have
not been well characterized, despite their co-occurrence in
a variety of environmental media. In two companion studies,
we examined the effects of developmental exposure to cadmium
(Cd) with or without co-exposure to prototypic PAHs
benzo[a]pyrene (BaP, Exp. 1) or fluoranthene (FA, Exp. 2)
using a developing zebrafish model. Zebrafish embryos were
exposed to Cd (0-0.3 μM), BaP (0-3 μM), FA (0-1.0 μM),
or binary Cd-PAH mixtures from 5 to 122 h post
fertilization (hpf). In Exp. 1, Cd and BaP produced
independent effects on an array of outcomes and interacting
effects on specific outcomes. Notably, Cd-induced deficits
in dark-induced locomotor stimulation were attenuated by BaP
co-exposure in the larval motility test and BaP-induced
hyperactivity was attenuated by Cd co-exposure in the
adolescent novel tank test. Likewise, in Exp. 2, Cd and FA
produced both independent and interacting effects.
FA-induced increases on adult post-tap activity in the tap
startle test were attenuated by co-exposure with Cd. On the
predator avoidance test, FA- and 0.3 μM Cd-induced
hyperactivity effects were attenuated by their co-exposure.
Taken together, these data indicate that while the effects
of Cd and these representative PAHs on zebrafish behavior
were largely independent of one another, binary mixtures can
produce sub-additive effects for some neurobehavioral
outcomes and at certain ages. This research emphasizes the
need for detailed risk assessments of mixtures containing
contaminants of differing classes, and for clarity on the
mechanisms which allow cross-class toxicant interactions to
occur.},
Doi = {10.1016/j.ntt.2024.107339},
Key = {fds376269}
}
@article{fds372839,
Author = {Kozal, JS and Jayasundara, N and Massarsky, A and Lindberg, CD and Oliveri, AN and Cooper, EM and Levin, ED and Meyer, JN and Giulio,
RTD},
Title = {Mitochondrial dysfunction and oxidative stress contribute to
cross-generational toxicity of benzo(a)pyrene in Danio
rerio.},
Journal = {Aquat Toxicol},
Volume = {263},
Pages = {106658},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1016/j.aquatox.2023.106658},
Abstract = {The potential for polycyclic aromatic hydrocarbons (PAHs) to
have adverse effects that persist across generations is an
emerging concern for human and wildlife health. This study
evaluated the role of mitochondria, which are maternally
inherited, in the cross-generational toxicity of
benzo(a)pyrene (BaP), a model PAH and known mitochondrial
toxicant. Mature female zebrafish (F0) were fed diets
containing 0, 12.5, 125, or 1250 μg BaP/g at a feed rate
of 1% body weight twice/day for 21 days. These females were
bred with unexposed males, and the embryos (F1) were
collected for subsequent analyses. Maternally-exposed
embryos exhibited altered mitochondrial function and
metabolic partitioning (i.e. the portion of respiration
attributable to different cellular processes), as evidenced
by in vivo oxygen consumption rates (OCRs). F1 embryos had
lower basal and mitochondrial respiration and ATP
turnover-mediated OCR, and increased proton leak and reserve
capacity. Reductions in mitochondrial DNA (mtDNA) copy
number, increases in mtDNA damage, and alterations in
biomarkers of oxidative stress were also found in
maternally-exposed embryos. Notably, the mitochondrial
effects in offspring occurred largely in the absence of
effects in maternal ovaries, suggesting that PAH-induced
mitochondrial dysfunction may manifest in subsequent
generations. Maternally-exposed larvae also displayed
swimming hypoactivity. The lowest observed effect level
(LOEL) for maternal BaP exposure causing mitochondrial
effects in offspring was 12.5 µg BaP/g diet (nominally
equivalent to 250 ng BaP/g fish). It was concluded that
maternal BaP exposure can cause significant mitochondrial
impairments in offspring.},
Doi = {10.1016/j.aquatox.2023.106658},
Key = {fds372839}
}
@article{fds370723,
Author = {Hawkey, AB and Unal, D and Holloway, ZR and Levin,
ED},
Title = {Developmental exposure of zebrafish to neonicotinoid
pesticides: Long-term effects on neurobehavioral
function.},
Journal = {Neurotoxicology},
Volume = {96},
Pages = {240-253},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1016/j.neuro.2023.05.003},
Abstract = {Neonicotinoid compounds are commonly used insecticides which
have become increasingly used as replacements of older
generations of insecticides, such as organophosphates. Given
the established neurotoxicity of cholinergic toxicants,
developmental neurotoxicity studies are needed to identify
in vertebrate species the potential toxicity of these
insecticides which act on nicotinic cholinergic receptors.
Previously, developmental exposure to a neonicotinoid
insecticide imidacloprid was shown to cause persisting
neurobehavioral toxicity in zebrafish. The current study
evaluated neurobehavioral effects of embryonic exposure to
two other neonicotinoid insecticides, clothianidin
(1-100 µM) and dinotefuran (1-100 µM) in zebrafish
(5-120 h post-fertilization), concentrations below the
threshold for increased lethality and overt
dysmorphogenesis. Neurobehavioral tests were conducted at
larval (6 days), adolescent (10 weeks) and adult (8 months)
ages. Both compounds caused short-term behavioral effects on
larval motility, although these effects were distinct from
one another. At a lower concentration (1 µM) clothianidin
increased dark-induced locomotor stimulation the second time
the lights turned off, while a higher concentration
(100 µM) reduced activity in the dark at its second
presentation. By contrast, dinotefuran (10-100 µM) caused
a general decrease in locomotion. Specific longer-term
neurobehavioral toxicity after early developmental exposure
was also seen. clothianidin (100 µM) reduced locomotor
activity in the novel tank in adolescence and adulthood, as
well as reduced baseline activity in the tap startle test
(1-100 µM) and reduced activity early (1-10 µM) or
throughout the predator avoidance test session (100 µM).
In addition to locomotor effects, clothianidin altered the
diving response in a dose-, age- and time-block-dependent
manner (1 µM, 100 µM), causing fish to remain further
away from a fast predator cue (100 µM) relative to
controls. Dinotefuran produced comparatively fewer effects,
increasing the diving response in adulthood (10 µM), but
not adolescence, and suppressing initial locomotor activity
in the predator avoidance test (1-10 µM). These data
indicate that neonicotinoid insecticides may carry some of
the same risks for vertebrates posed by other classes of
insecticides, and that these adverse behavioral consequences
of early developmental exposure are evident well into
adulthood.},
Doi = {10.1016/j.neuro.2023.05.003},
Key = {fds370723}
}
@article{fds367718,
Author = {Hawkey, AB and Evans, J and Holloway, ZR and Pippen, E and Jarrett, O and Kenou, B and Slotkin, TA and Seidler, FJ and Levin,
ED},
Title = {Developmental exposure to the flame retardant, triphenyl
phosphate, causes long-lasting neurobehavioral and
neurochemical dysfunction.},
Journal = {Birth Defects Res},
Volume = {115},
Number = {3},
Pages = {357-370},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1002/bdr2.2125},
Abstract = {BACKGROUND: Human exposures to organophosphate flame
retardants result from their use as additives in numerous
consumer products. These agents are replacements for
brominated flame retardants but have not yet faced similar
scrutiny for developmental neurotoxicity. We examined a
representative organophosphate flame retardant, triphenyl
phosphate (TPP) and its potential effects on behavioral
development and dopaminergic function. METHODS: Female
Sprague-Dawley rats were given low doses of TPP (16 or
32 mg kg-1 day-1 ) via subcutaneous osmotic minipumps,
begun preconception and continued into the early postnatal
period. Offspring were administered a battery of behavioral
tests from adolescence into adulthood, and littermates were
used to evaluate dopaminergic synaptic function. RESULTS:
Offspring with TPP exposures showed increased latency to
begin eating in the novelty-suppressed feeding test,
impaired object recognition memory, impaired choice accuracy
in the visual signal detection test, and sex-selective
effects on locomotor activity in adolescence (males) but not
adulthood. Male, but not female, offspring showed marked
increases in dopamine utilization in the striatum, evidenced
by an increase in the ratio of the primary dopamine
metabolite (3,4-dihydroxyphenylacetic acid) relative to
dopamine levels. CONCLUSIONS: These results indicate that
TPP has adverse effects that are similar in some respects to
those of organophosphate pesticides, which were restricted
because of their developmental neurotoxicity.},
Doi = {10.1002/bdr2.2125},
Key = {fds367718}
}
@misc{fds376750,
Author = {Levin, ED},
Title = {Behavioral toxicology},
Volume = {1},
Pages = {V1-927-V1-931},
Booktitle = {Encyclopedia of Toxicology, Fourth Edition: Volume
1-9},
Year = {2023},
Month = {January},
ISBN = {9780128243152},
url = {http://dx.doi.org/10.1016/B978-0-12-824315-2.01047-2},
Abstract = {(A) Definition. Behavioral toxicology analyzes the adverse
functional effects of toxic actions in the brain. (B)
Process. This section presents the spectrum of behavioral
tests of cognition, emotional functions, as well as other
behavioral functions, their use across ages and species and
the integration of behavioral toxicology with other
neurotoxicology approaches. Mechanistic analysis from
behavioral function back to more component processes can
converge with the forward mechanistic analysis. (C)
Conclusion. Behavioral toxicology provides a clear link of
toxicant exposure to the functions of concern to human
neurotoxicity and provides a way to discern which neurotoxic
effects cause functional impairment.},
Doi = {10.1016/B978-0-12-824315-2.01047-2},
Key = {fds376750}
}
@article{fds369719,
Author = {Hawkey, AB and Mead, M and Natarajan, S and Gondal, A and Jarrett, O and Levin, ED},
Title = {Embryonic exposure to PFAS causes long-term,
compound-specific behavioral alterations in
zebrafish.},
Journal = {Neurotoxicol Teratol},
Volume = {97},
Pages = {107165},
Year = {2023},
url = {http://dx.doi.org/10.1016/j.ntt.2023.107165},
Abstract = {Per- and polyfluoroalkyl substances (PFAS) are commonly used
as surfactants and coatings for industrial processes and
consumer products. These compounds have been increasingly
detected in drinking water and human tissue, and concern
over their potential effects on health and development is
growing. However, relatively little data are available for
their potential impacts on neurodevelopment and the degree
to which different compounds within this class may differ
from one another in their neurotoxicity. The present study
examined the neurobehavioral toxicology of two
representative compounds in a zebrafish model. Zebrafish
embryos were exposed to 0.1-100uM perfluorooctanoic acid
(PFOA) or 0.01-1.0uM perfluorooctanesulfonic acid (PFOS)
from 5 to 122 h post-fertilization. These concentrations
were below threshold for producing increased lethality or
overt dysmorphologies, and PFOA was tolerated at a
concentration 100× higher than PFOS. Fish were maintained
to adulthood, with behavioral assessments at 6 days,
3 months (adolescence) and 8 months of age (adulthood).
Both PFOA and PFOS caused behavioral changes in zebrafish,
but PFOS and PFOS produced strikingly different phenotypes.
PFOA was associated with increased larval motility in the
dark (100uM), and enhanced diving responses in adolescence
(100uM) but not adulthood. PFOS was associated with a
reversed light-dark response in the larval motility test
(0.1-1uM), whereby the fish were more active in the light
than the dark. PFOS also caused time-dependent changes in
locomotor activity in the novel tank test during adolescence
(0.1-1.0uM) and an overall pattern of hypoactivity in
adulthood at the lowest concentration (0.01uM).
Additionally, the lowest concentration of PFOS (0.01uM)
reduced acoustic startle magnitude in adolescence, but not
adulthood. These data suggest that PFOS and PFOA both
produce neurobehavioral toxicity, but these effects are
quite distinct from one another.},
Doi = {10.1016/j.ntt.2023.107165},
Key = {fds369719}
}
%% Li, Pearl Han
@article{fds376794,
Author = {Li, PH and Koenig, MA},
Title = {Understanding the role of testimony in children's moral
development: Theories, controversies, and
implications},
Journal = {Developmental Review},
Volume = {67},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1016/j.dr.2022.101053},
Doi = {10.1016/j.dr.2022.101053},
Key = {fds376794}
}
%% Li, Rosa
@article{fds369953,
Author = {Li, R},
Title = {Children are adaptive decision-makers: how environment
shapes decision preferences.},
Journal = {Proceedings of the Royal Society B: Biological
Sciences},
Volume = {290},
Number = {1995},
Pages = {20222117},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1098/rspb.2022.2117},
Doi = {10.1098/rspb.2022.2117},
Key = {fds369953}
}
%% Lisanby, Sarah H.
@article{fds371882,
Author = {Deng, Z-D and Robins, PL and Regenold, W and Rohde, P and Dannhauer, M and Lisanby, SH},
Title = {How electroconvulsive therapy works in the treatment of
depression: is it the seizure, the electricity, or
both?},
Journal = {Neuropsychopharmacology},
Volume = {49},
Number = {1},
Pages = {150-162},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1038/s41386-023-01677-2},
Abstract = {We have known for nearly a century that triggering seizures
can treat serious mental illness, but what we do not know is
why. Electroconvulsive Therapy (ECT) works faster and better
than conventional pharmacological interventions; however,
those benefits come with a burden of side effects, most
notably memory loss. Disentangling the mechanisms by which
ECT exerts rapid therapeutic benefit from the mechanisms
driving adverse effects could enable the development of the
next generation of seizure therapies that lack the downside
of ECT. The latest research suggests that this goal may be
attainable because modifications of ECT technique have
already yielded improvements in cognitive outcomes without
sacrificing efficacy. These modifications involve changes in
how the electricity is administered (both where in the
brain, and how much), which in turn impacts the
characteristics of the resulting seizure. What we do not
completely understand is whether it is the changes in the
applied electricity, or in the resulting seizure, or both,
that are responsible for improved safety. Answering this
question may be key to developing the next generation of
seizure therapies that lack these adverse side effects, and
ushering in novel interventions that are better, faster, and
safer than ECT.},
Doi = {10.1038/s41386-023-01677-2},
Key = {fds371882}
}
@article{fds374444,
Author = {Mukhtar, F and Feuer, E and Beynel, L and Jones, E and Regenold, WT and Lisanby, SH},
Title = {Distinguishing Convulsive Syncope From Seizure Induced by
Repetitive Transcranial Magnetic Stimulation: A Case
Report.},
Journal = {J Ect},
Volume = {39},
Number = {4},
Pages = {271-273},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1097/YCT.0000000000000959},
Abstract = {Repetitive transcranial magnetic stimulation (rTMS) is Food
and Drug Administration cleared for clinical use in
treatment-resistant depression and a growing list of other
disorders. The clinical uptake of rTMS has been facilitated
by its relatively benign adverse-effect profile compared
with other treatment modalities. Seizure is a rare but
serious adverse event that has been reported with rTMS, when
dosage exceeds safety guidelines or in individuals at
increased risk for seizure. Fortunately, most rTMS-induced
seizures are typically transient, with no adverse sequelae,
but they may lead to treatment discontinuation. Seizure is
not the only cause of loss of conscious and abnormal
movements induced by rTMS. Convulsive syncope, a more common
adverse event that involves loss of consciousness associated
with myoclonic movements, can be difficult to differentiate
from an rTMS-induced seizure. We report the case of a
52-year-old man with no known seizure risk factors, enrolled
in an institutional review board-approved research study who
developed what appeared to be a convulsive syncopal episode
lasting 10 to 15 seconds during day 2 of a 30-day rTMS
protocol (10 Hz, 120% of motor threshold, 4-second pulse
train, 26-second intertrain interval, 3000 pulses per
session), with no adverse sequelae. The patient's history,
screening, physical examination, pertinent laboratory,
neurology consult, electroencephalogram, and imaging
findings are discussed. This case demonstrates that
distinguishing between convulsive syncope and rTMS-induced
seizure can be a diagnostic challenge. Clinicians and
researchers delivering rTMS should be familiar with the risk
factors for rTMS-induced seizures and rTMS-induced
convulsive syncope, to screen for predisposing factors and
to manage these rare adverse events if they
occur.},
Doi = {10.1097/YCT.0000000000000959},
Key = {fds374444}
}
@article{fds373516,
Author = {Oberman, LM and Francis, SM and Lisanby, SH},
Title = {The use of noninvasive brain stimulation techniques in
autism spectrum disorder.},
Journal = {Autism Res},
Publisher = {WILEY},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1002/aur.3041},
Abstract = {Noninvasive brain stimulation (NIBS) techniques, including
repetitive transcranial magnetic stimulation (rTMS) and
transcranial direct current stimulation (tDCS), have
recently emerged as alternative, nonpharmacological
interventions for a variety of psychiatric, neurological,
and neurodevelopmental conditions. NIBS is beginning to be
applied in both research and clinical settings for the
treatment of core and associated symptoms of autism spectrum
disorder (ASD) including social communication deficits,
restricted and repetitive behaviors, irritability,
hyperactivity, depression and impairments in executive
functioning and sensorimotor integration. Though there is
much promise for these targeted device-based interventions,
in other disorders (including adult major depressive
disorder (MDD) and obsessive compulsive disorder (OCD) where
rTMS is FDA cleared), data on the safety and efficacy of
these interventions in individuals with ASD is limited
especially in younger children when neurodevelopmental
interventions typically begin. Most studies are open-label,
small scale, and/or focused on a restricted subgroup of
individuals with ASD. There is a need for larger, randomized
controlled trials that incorporate neuroimaging in order to
develop predictive biomarkers of treatment response and
optimize treatment parameters. We contend that until such
studies are conducted, we do not have adequate estimates of
the safety and efficacy of NIBS interventions in children
across the spectrum. Thus, broad off-label use of these
techniques in this population is not supported by currently
available evidence. Here we discuss the existing data on the
use of NIBS to treat symptoms related to ASD and discuss
future directions for the field.},
Doi = {10.1002/aur.3041},
Key = {fds373516}
}
@article{fds372238,
Author = {Darrow, SM and Pizzagalli, DA and Smoski, M and Mathew, SJ and Nurnberger, J and Lisanby, SH and Iosifescu, D and Murrough, JW and Yang, H and Weiner, RD and Sanacora, G and Keefe, RSE and Song, A and Goodman, W and Whitton, AE and Potter, WZ and Krystal,
AD},
Title = {Using latent profile analyses to classify subjects with
anhedonia based on reward-related measures obtained in the
FAST-MAS study.},
Journal = {J Affect Disord},
Volume = {339},
Pages = {584-592},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1016/j.jad.2023.07.081},
Abstract = {BACKGROUND: Growing evidence indicates that anhedonia is a
multifaceted construct. This study examined the possibility
of identifying subgroups of people with anhedonia using
multiple reward-related measures to provide greater
understanding the Research Domain Criteria's Positive
Valence Systems Domain and pathways for developing
treatments. METHODS: Latent profile analysis of baseline
data from a study that examined the effects of a novel kappa
opioid receptor (KOR) antagonist drug on measures and
biomarkers associated with anhedonia was used to identify
subgroups. Measures included ventral striatal activation
during the Monetary Incentive Delay task, response bias in
the Probabilistic Reward Task, reward valuation scores from
the Effort-Expenditure for Rewards Task, and scores from
reward-related self-report measures. RESULTS: Two subgroups
were identified, which differed on self-report measures of
reward. Participants in the subgroup reporting more
anhedonia also reported more depression and had greater
illness severity and functional impairments. Graphs of
change with treatment showed a trend for the less severe
subgroup to demonstrate higher response to KOR antagonist
treatment on the neuroimaging measure, probabilistic reward
task, and ratings of functioning; the subgroup with greater
severity showed a trend for higher treatment response on
reward-related self-report measures. LIMITATIONS: The main
limitations include the small sample size and exploratory
nature of analyses. CONCLUSIONS: Evidence of possible
dissociation between self-reported measures of anhedonia and
other measures with respect to treatment response emerged.
These results highlight the importance for future research
to consider severity of self-reported reward-related
deficits and how the relationship across measurement methods
may vary with severity.},
Doi = {10.1016/j.jad.2023.07.081},
Key = {fds372238}
}
@article{fds370915,
Author = {Lisanby, SH},
Title = {Transcranial Magnetic Stimulation in Psychiatry: Historical
Reflections and Future Directions.},
Journal = {Biol Psychiatry},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1016/j.biopsych.2023.05.001},
Doi = {10.1016/j.biopsych.2023.05.001},
Key = {fds370915}
}
@article{fds371283,
Author = {Mukhtar, F and Regenold, W and Lisanby, SH},
Title = {Recent advances in electroconvulsive therapy in clinical
practice and research.},
Journal = {Fac Rev},
Volume = {12},
Pages = {13},
Year = {2023},
url = {http://dx.doi.org/10.12703/r/12-13},
Abstract = {Electroconvulsive therapy (ECT), the oldest somatic therapy
still in use in psychiatry today, remains one of the most
effective therapeutic interventions for a wide variety of
psychiatric disorders. In this article, we review some of
the recent advances in ECT that are currently being
researched and implemented in clinical practice. We explore
recent studies that point to the potential therapeutic
benefit and safety of ECT in COVID-19-related
neuropsychiatric complications and special populations (such
as the elderly and pregnant persons) that are generally at
higher risk of having adverse effects from psychotropic
medications. We highlight studies that performed a
head-to-head comparison of ECT and ketamine, which has shown
promise for treatment-resistant depression and acute
suicidality. Researchers continue to explore different ways
of using ECT by modifying the treatment parameters to
maintain efficacy and decrease side effects. Neurocognitive
side effects remain one of the major drawbacks to its use
and contribute to the negative stigma of this highly
effective treatment. In this regard, we describe attempts to
improve the safety of ECT by modifying dosing parameters,
novel electrode placements, and the addition of augmenting
agents with the aim of decreasing side effects and improving
efficacy. This review identifies some of the recent advances
in the last few years in ECT research while also
highlighting areas where further research is
needed.},
Doi = {10.12703/r/12-13},
Key = {fds371283}
}
@article{fds369961,
Author = {Davis, SW and Beynel, L and Neacsiu, AD and Luber, BM and Bernhardt, E and Lisanby, SH and Strauman, TJ},
Title = {Network-level dynamics underlying a combined rTMS and
psychotherapy treatment for major depressive disorder: An
exploratory network analysis.},
Journal = {Int J Clin Health Psychol},
Volume = {23},
Number = {4},
Pages = {100382},
Year = {2023},
url = {http://dx.doi.org/10.1016/j.ijchp.2023.100382},
Abstract = {BACKGROUND: Despite the growing use of repetitive
transcranial magnetic stimulation (rTMS) as a treatment for
depression, there is a limited understanding of the
mechanisms of action and how potential treatment-related
brain changes help to characterize treatment response. To
address this gap in understanding we investigated the
effects of an approach combining rTMS with simultaneous
psychotherapy on global functional connectivity. METHOD: We
compared task-related functional connectomes based on an
idiographic goal priming task tied to emotional regulation
acquired before and after simultaneous rTMS/psychotherapy
treatment for patients with major depressive disorders and
compared these changes to normative connectivity patterns
from a set of healthy volunteers (HV) performing the same
task. RESULTS: At baseline, compared to HVs, patients
demonstrated hyperconnectivity of the DMN, cerebellum and
limbic system, and hypoconnectivity of the fronto-parietal
dorsal-attention network and visual cortex. Simultaneous
rTMS/psychotherapy helped to normalize these differences,
which were reduced after treatment. This finding suggests
that the rTMS/therapy treatment regularizes connectivity
patterns in both hyperactive and hypoactive brain networks.
CONCLUSIONS: These results help to link treatment to a
comprehensive model of the neurocircuitry underlying
depression and pave the way for future studies using
network-guided principles to significantly improve rTMS
efficacy for depression.},
Doi = {10.1016/j.ijchp.2023.100382},
Key = {fds369961}
}
@article{fds370914,
Author = {Hitti, FL and Widge, AS and Riva-Posse, P and Malone, DA and Okun, MS and Shanechi, MM and Foote, KD and Lisanby, SH and Ankudowich, E and Chivukula, S and Chang, EF and Gunduz, A and Hamani, C and Feinsinger,
A and Kubu, CS and Chiong, W and Chandler, JA and Carbunaru, R and Cheeran,
B and Raike, RS and Davis, RA and Halpern, CH and Vanegas-Arroyave, N and Markovic, D and Bick, SK and McIntyre, CC and Richardson, RM and Dougherty, DD and Kopell, BH and Sweet, JA and Goodman, WK and Sheth,
SA and Pouratian, N},
Title = {Future directions in psychiatric neurosurgery: Proceedings
of the 2022 American Society for Stereotactic and Functional
Neurosurgery meeting on surgical neuromodulation for
psychiatric disorders.},
Journal = {Brain Stimul},
Volume = {16},
Number = {3},
Pages = {867-878},
Year = {2023},
url = {http://dx.doi.org/10.1016/j.brs.2023.05.011},
Abstract = {OBJECTIVE: Despite advances in the treatment of psychiatric
diseases, currently available therapies do not provide
sufficient and durable relief for as many as 30-40% of
patients. Neuromodulation, including deep brain stimulation
(DBS), has emerged as a potential therapy for persistent
disabling disease, however it has not yet gained widespread
adoption. In 2016, the American Society for Stereotactic and
Functional Neurosurgery (ASSFN) convened a meeting with
leaders in the field to discuss a roadmap for the path
forward. A follow-up meeting in 2022 aimed to review the
current state of the field and to identify critical barriers
and milestones for progress. DESIGN: The ASSFN convened a
meeting on June 3, 2022 in Atlanta, Georgia and included
leaders from the fields of neurology, neurosurgery, and
psychiatry along with colleagues from industry, government,
ethics, and law. The goal was to review the current state of
the field, assess for advances or setbacks in the interim
six years, and suggest a future path forward. The
participants focused on five areas of interest:
interdisciplinary engagement, regulatory pathways and trial
design, disease biomarkers, ethics of psychiatric surgery,
and resource allocation/prioritization. The proceedings are
summarized here. CONCLUSION: The field of surgical
psychiatry has made significant progress since our last
expert meeting. Although weakness and threats to the
development of novel surgical therapies exist, the
identified strengths and opportunities promise to move the
field through methodically rigorous and biologically-based
approaches. The experts agree that ethics, law, patient
engagement, and multidisciplinary teams will be critical to
any potential growth in this area.},
Doi = {10.1016/j.brs.2023.05.011},
Key = {fds370914}
}
@article{fds371723,
Author = {Brady, LS and Lisanby, SH and Gordon, JA},
Title = {New directions in psychiatric drug development: promising
therapeutics in the pipeline.},
Journal = {Expert Opin Drug Discov},
Volume = {18},
Number = {8},
Pages = {835-850},
Year = {2023},
url = {http://dx.doi.org/10.1080/17460441.2023.2224555},
Abstract = {INTRODUCTION: Psychiatric disorders are a leading cause of
disability worldwide, calling for an urgent need for new
treatments, early detection, early intervention, and
precision medicine. Drug discovery and development in
psychiatry continues to expand in new and exciting areas,
with several new medications approved for psychiatric
indications by the U.S. Food and Drug Administration (FDA)
in the last 5 years. AREAS COVERED: In this review, the
authors summarize recent new drug approvals and new
molecular mechanisms in Phase 1-3 clinical development for
psychiatric disorders. Advances in human genetics-driven
target identification, emergent technologies such as
artificial intelligence-enabled drug discovery, digital
health technologies, and biomarker tools and strategies for
testing novel mechanisms are highlighted. EXPERT OPINION:
There continues to be a need for research focused on
understanding the natural history, developmental trajectory,
and pathophysiology of psychiatric disorders to identify new
molecular and circuit-based targets. Looking to the future,
a vision of precision psychiatry is emerging, taking
advantage of advances in genetics, digital technology, and
multimodal biomarkers to accelerate the development of
next-generation therapies for individuals living with mental
illnesses.},
Doi = {10.1080/17460441.2023.2224555},
Key = {fds371723}
}
%% Madden, David J.
@article{fds375498,
Author = {Merenstein, JL and Zhao, J and Overson, DK and Truong, T-K and Johnson,
KG and Song, AW and Madden, DJ},
Title = {Depth- and curvature-based quantitative susceptibility
mapping analyses of cortical iron in Alzheimer's
disease.},
Journal = {Cereb Cortex},
Volume = {34},
Number = {2},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1093/cercor/bhad525},
Abstract = {In addition to amyloid beta plaques and neurofibrillary
tangles, Alzheimer's disease (AD) has been associated with
elevated iron in deep gray matter nuclei using quantitative
susceptibility mapping (QSM). However, only a few studies
have examined cortical iron, using more macroscopic
approaches that cannot assess layer-specific differences.
Here, we conducted column-based QSM analyses to assess
whether AD-related increases in cortical iron vary in
relation to layer-specific differences in the type and
density of neurons. We obtained global and regional measures
of positive (iron) and negative (myelin, protein
aggregation) susceptibility from 22 adults with AD and 22
demographically matched healthy controls. Depth-wise
analyses indicated that global susceptibility increased from
the pial surface to the gray/white matter boundary, with a
larger slope for positive susceptibility in the left
hemisphere for adults with AD than controls. Curvature-based
analyses indicated larger global susceptibility for adults
with AD versus controls; the right hemisphere versus left;
and gyri versus sulci. Region-of-interest analyses
identified similar depth- and curvature-specific group
differences, especially for temporo-parietal regions.
Finding that iron accumulates in a topographically
heterogenous manner across the cortical mantle may help
explain the profound cognitive deterioration that
differentiates AD from the slowing of general motor
processes in healthy aging.},
Doi = {10.1093/cercor/bhad525},
Key = {fds375498}
}
@article{fds375497,
Author = {Stout, JA and Mahzarnia, A and Dai, R and Anderson, RJ and Cousins, S and Zhuang, J and Lad, EM and Whitaker, DB and Madden, DJ and Potter, GG and Whitson, HE and Badea, A},
Title = {Accelerated Brain Atrophy, Microstructural Decline and
Connectopathy in Age-Related Macular Degeneration.},
Journal = {Biomedicines},
Volume = {12},
Number = {1},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.3390/biomedicines12010147},
Abstract = {Age-related macular degeneration (AMD) has recently been
linked to cognitive impairment. We hypothesized that AMD
modifies the brain aging trajectory, and we conducted a
longitudinal diffusion MRI study on 40 participants (20 with
AMD and 20 controls) to reveal the location, extent, and
dynamics of AMD-related brain changes. Voxel-based analyses
at the first visit identified reduced volume in AMD
participants in the cuneate gyrus, associated with vision,
and the temporal and bilateral cingulate gyrus, linked to
higher cognition and memory. The second visit occurred 2
years after the first and revealed that AMD participants had
reduced cingulate and superior frontal gyrus volumes, as
well as lower fractional anisotropy (FA) for the bilateral
occipital lobe, including the visual and the superior
frontal cortex. We detected faster rates of volume and FA
reduction in AMD participants in the left temporal cortex.
We identified inter-lingual and lingual-cerebellar
connections as important differentiators in AMD
participants. Bundle analyses revealed that the lingual
gyrus had a lower streamline length in the AMD participants
at the first visit, indicating a connection between retinal
and brain health. FA differences in select inter-lingual and
lingual cerebellar bundles at the second visit showed
downstream effects of vision loss. Our analyses revealed
widespread changes in AMD participants, beyond brain
networks directly involved in vision processing.},
Doi = {10.3390/biomedicines12010147},
Key = {fds375497}
}
@article{fds373426,
Author = {Madden, DJ and Merenstein, JL},
Title = {Quantitative susceptibility mapping of brain iron in healthy
aging and cognition.},
Journal = {Neuroimage},
Volume = {282},
Pages = {120401},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1016/j.neuroimage.2023.120401},
Abstract = {Quantitative susceptibility mapping (QSM) is a magnetic
resonance imaging (MRI) technique that can assess the
magnetic properties of cerebral iron in vivo. Although brain
iron is necessary for basic neurobiological functions,
excess iron content disrupts homeostasis, leads to oxidative
stress, and ultimately contributes to neurodegenerative
disease. However, some degree of elevated brain iron is
present even among healthy older adults. To better
understand the topographical pattern of iron accumulation
and its relation to cognitive aging, we conducted an
integrative review of 47 QSM studies of healthy aging, with
a focus on five distinct themes. The first two themes
focused on age-related increases in iron accumulation in
deep gray matter nuclei versus the cortex. The overall level
of iron is higher in deep gray matter nuclei than in
cortical regions. Deep gray matter nuclei vary with regard
to age-related effects, which are most prominent in the
putamen, and age-related deposition of iron is also observed
in frontal, temporal, and parietal cortical regions during
healthy aging. The third theme focused on the behavioral
relevance of iron content and indicated that higher iron in
both deep gray matter and cortical regions was related to
decline in fluid (speed-dependent) cognition. A handful of
multimodal studies, reviewed in the fourth theme, suggest
that iron interacts with imaging measures of brain function,
white matter degradation, and the accumulation of
neuropathologies. The final theme concerning modifiers of
brain iron pointed to potential roles of cardiovascular,
dietary, and genetic factors. Although QSM is a relatively
recent tool for assessing cerebral iron accumulation, it has
significant promise for contributing new insights into
healthy neurocognitive aging.},
Doi = {10.1016/j.neuroimage.2023.120401},
Key = {fds373426}
}
@article{fds371016,
Author = {Merenstein, JL and Zhao, J and Mullin, HA and Rudolph, MD and Song, AW and Madden, DJ},
Title = {High-resolution multi-shot diffusion imaging of structural
networks in healthy neurocognitive aging.},
Journal = {Neuroimage},
Volume = {275},
Pages = {120191},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1016/j.neuroimage.2023.120191},
Abstract = {Healthy neurocognitive aging has been associated with the
microstructural degradation of white matter pathways that
connect distributed gray matter regions, assessed by
diffusion-weighted imaging (DWI). However, the relatively
low spatial resolution of standard DWI has limited the
examination of age-related differences in the properties of
smaller, tightly curved white matter fibers, as well as the
relatively more complex microstructure of gray matter. Here,
we capitalize on high-resolution multi-shot DWI, which
allows spatial resolutions < 1 mm3 to be achieved on
clinical 3T MRI scanners. We assessed whether traditional
diffusion tensor-based measures of gray matter
microstructure and graph theoretical measures of white
matter structural connectivity assessed by standard
(1.5 mm3 voxels, 3.375 μl volume) and high-resolution
(1 mm3 voxels, 1μl volume) DWI were differentially related
to age and cognitive performance in 61 healthy adults 18-78
years of age. Cognitive performance was assessed using an
extensive battery comprising 12 separate tests of fluid
(speed-dependent) cognition. Results indicated that the
high-resolution data had larger correlations between age and
gray matter mean diffusivity, but smaller correlations
between age and structural connectivity. Moreover, parallel
mediation models including both standard and high-resolution
measures revealed that only the high-resolution measures
mediated age-related differences in fluid cognition. These
results lay the groundwork for future studies planning to
apply high-resolution DWI methodology to further assess the
mechanisms of both healthy aging and cognitive
impairment.},
Doi = {10.1016/j.neuroimage.2023.120191},
Key = {fds371016}
}
@article{fds369255,
Author = {Rapp, PR and Madden, DJ},
Title = {Editor transition at Neurobiology of Aging.},
Journal = {Neurobiol Aging},
Volume = {124},
Pages = {51},
Publisher = {Elsevier BV},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1016/j.neurobiolaging.2023.01.009},
Doi = {10.1016/j.neurobiolaging.2023.01.009},
Key = {fds369255}
}
@article{fds369256,
Author = {Merenstein, JL and Mullin, HA and Madden, DJ},
Title = {Age-related differences in frontoparietal activation for
target and distractor singletons during visual
search.},
Journal = {Atten Percept Psychophys},
Volume = {85},
Number = {3},
Pages = {749-768},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.3758/s13414-022-02640-x},
Abstract = {Age-related decline in visual search performance has been
associated with different patterns of activation in
frontoparietal regions using functional magnetic resonance
imaging (fMRI), but whether these age-related effects
represent specific influences of target and distractor
processing is unclear. Therefore, we acquired event-related
fMRI data from 68 healthy, community-dwelling adults ages
18-78 years, during both conjunction (T/F target among
rotated Ts and Fs) and feature (T/F target among Os) search.
Some displays contained a color singleton that could
correspond to either the target or a distractor. A diffusion
decision analysis indicated age-related increases in
sensorimotor response time across all task conditions, but
an age-related decrease in the rate of evidence accumulation
(drift rate) was specific to conjunction search. Moreover,
the color singleton facilitated search performance when
occurring as a target and disrupted performance when
occurring as a distractor, but only during conjunction
search, and these effects were independent of age. The fMRI
data indicated that decreased search efficiency for
conjunction relative to feature search was evident as
widespread frontoparietal activation. Activation within the
left insula mediated the age-related decrease in drift rate
for conjunction search, whereas this relation in the FEF and
parietal cortex was significant only for individuals younger
than 30 or 44 years, respectively. Finally, distractor
singletons were associated with significant parietal
activation, whereas target singletons were associated with
significant frontoparietal deactivation, and this latter
effect increased with adult age. Age-related differences in
frontoparietal activation therefore reflect both the overall
efficiency of search and the enhancement from salient
targets.},
Doi = {10.3758/s13414-022-02640-x},
Key = {fds369256}
}
%% March, John S.
@article{fds138619,
Title = {March, J., Parker, J., Sullivan, K., Stallings, P., Conners,
C. (in press), The Multidimensional Anxiety Scale for
Children (MASC): Factor structure, reliability and validity.
J Am Acad Child Adolesc Psychiatry},
Key = {fds138619}
}
@article{fds138635,
Title = {March, J., Amaya-Jackson, L., Costanzo, P., Terry, R. (in
press), Post-traumatic stress in children and adolescents
after an industrial fire. Journal of the American Academy of
Child and Adolescent Psychiatry},
Key = {fds138635}
}
%% Marsh, Elizabeth J.
@article{fds371649,
Author = {Stanley, ML and Huang, S and Marsh, EJ and Kay, AC},
Title = {The Role of Structure-Seeking in Moral Punishment},
Journal = {Social Justice Research},
Volume = {36},
Number = {4},
Pages = {410-431},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1007/s11211-023-00416-8},
Abstract = {Four studies (total N = 1586) test the notion that people
are motivated to punish moral rule violators because
punishment offers a way to obtain structure and order in the
world. First, in a correlational study, increased need for
structure was associated with the stronger endorsement
punishment for moral rule violators. This relationship
between need for structure and punishment was not driven by
political conservatism. Three experimental studies then
tested, and corroborated, our main causal hypotheses: that
threats to structure increase punitive judgments for moral
rule violators (i.e., a compensatory mechanism; Study 2) and
that a lack of punishment for wrongdoing (relative to
punishment for wrongdoing) makes the world seem less
structured in the moment (Studies 3 and 4). We compare and
contrast our structure-based account of moral punishment to
other theories and findings across the punishment
literature.},
Doi = {10.1007/s11211-023-00416-8},
Key = {fds371649}
}
@article{fds371744,
Author = {Taylor, MK and Marsh, EJ and Samanez-Larkin, GR},
Title = {Heuristic decision-making across adulthood.},
Journal = {Psychology and aging},
Volume = {38},
Number = {6},
Pages = {508-518},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1037/pag0000726},
Abstract = {In general, research on aging and decision-making has grown
in recent years. Yet, little work has investigated how
reliance on classic heuristics may differ across adulthood.
For example, younger adults rely on the availability of
information from memory when judging the relative frequency
of plane crashes versus car accidents, but it is unclear if
older adults are similarly reliant on this heuristic. In the
present study, participants aged 20-90 years old made
judgments that could be answered by relying on five
different heuristics: anchoring, availability, recognition,
representativeness, and sunk-cost bias. We found no evidence
of age-related differences in the use of the classic
heuristics-younger and older adults employed anchoring,
availability, recognition, and representativeness to equal
degrees in order to make decisions. However, replicating
past work, we found age-related differences in the sunk-cost
bias-older adults were more likely to avoid this fallacy
compared to younger adults. We explain these different
patterns by drawing on the distinctive roles that stored
knowledge and personal experience likely play across
heuristics. (PsycInfo Database Record (c) 2023 APA, all
rights reserved).},
Doi = {10.1037/pag0000726},
Key = {fds371744}
}
@article{fds370236,
Author = {Eliseev, ED and Marsh, EJ},
Title = {Understanding why searching the internet inflates confidence
in explanatory ability},
Journal = {Applied Cognitive Psychology},
Volume = {37},
Number = {4},
Pages = {711-720},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1002/acp.4058},
Abstract = {People rely on the internet for easy access to information,
setting up potential confusion about the boundaries between
an individual's knowledge and the information they find
online. Across four experiments, we replicated and extended
past work showing that online searching inflates people's
confidence in their knowledge. Participants who searched the
internet for explanations rated their explanatory ability
higher than participants who read but did not search for the
same explanations. Two experiments showed that extraneous
web page content (pictures) does not drive this effect. The
last experiment modeled how search engines yield results;
participants saw (but did not search for) a list of hits,
which included “snippets” that previewed web page
content, before reading the explanations. Participants in
this condition were as confident as participants who
searched online. Previewing hits primes to-be-read content,
in a modern-day equivalent of Titchener's famous example of
a brief glance eliciting false feelings of
familiarity.},
Doi = {10.1002/acp.4058},
Key = {fds370236}
}
@article{fds371568,
Author = {Stone, AR and Marsh, EJ},
Title = {Belief in COVID-19 misinformation: Hopeful claims are rated
as truer},
Journal = {Applied Cognitive Psychology},
Volume = {37},
Number = {2},
Pages = {399-408},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1002/acp.4042},
Abstract = {Misinformation surrounding COVID-19 spread rapidly and
widely, posing a significant threat to public health. Here,
we examined whether some types of misinformation are more
believable than others, to the extent that they offer people
hope in uncertain times. An initial group of subjects rated
a series of COVID-19 misinformation statements for whether
each made them feel more or less hopeful (if true). Based on
these ratings, we selected two sets of misinformation that
differed in their average rated hopefulness; the two sets
did not differ in word length or reading ease. In two
studies, people rated their belief in each statement.
Results from both studies revealed that people rated the
more hopeful misinformation (e.g., COVID cures and
prevention methods) as truer than less hopeful
misinformation (e.g., transmission vectors). These findings
are consistent with a motivated reasoning account of
misinformation acceptance.},
Doi = {10.1002/acp.4042},
Key = {fds371568}
}
%% Mazuka, Reiko
@article{fds371461,
Author = {Choi, Y and Nam, M and Yamane, N and Mazuka, R},
Title = {Lack of early sensitivity and gradual emergence of native
phoneme categories: A pattern from underrepresented language
learners.},
Journal = {Developmental Science},
Pages = {e13422},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1111/desc.13422},
Abstract = {Perceptual narrowing of speech perception supposes that
young infants can discriminate most speech sounds early in
life. During the second half of the first year, infants'
phonetic sensitivity is attuned to their native phonology.
However, supporting evidence for this pattern comes
primarily from learners from a limited number of regions and
languages. Very little evidence has accumulated on infants
learning languages spoken in Asia, which accounts for most
of the world's population. The present study examined the
developmental trajectory of Korean-learning infants'
sensitivity to a native stop contrast during the first year
of life. The Korean language utilizes unusual voiceless
three-way stop categories, requiring target categories to be
derived from tight phonetic space. Further, two of these
categories-lenis and aspirated-have undergone a diachronic
change in recent decades as the primary acoustic cue for
distinction has shifted among modern speakers. Consequently,
the input distributions of these categories are mixed across
speakers and speech styles, requiring learners to build
flexible representations of target categories along these
variations. The results showed that among the three age
groups-4-6 months, 7-9 months, and 10-12 months-we tested,
only 10-12-month-olds showed weak sensitivity to the two
categories, suggesting that robust discrimination is not in
place by the end of the first year. The study adds scarcely
represented data, lending additional support for the lack of
early sensitivity and prolonged emergence of native
phonology that are inconsistent with learners of predominant
studies and calls for more diverse samples to verify the
generality of the typical perceptual narrowing pattern.
RESEARCH HIGHLIGHTS: We investigated Korean-learning
infants' developmental trajectory of native phoneme
categories and whether they show the typical perceptual
narrowing pattern. Robust discrimination did not appear
until 12 months, suggesting that Korean infants' native
phonology is not stabilized by the end of the first year.
The prolonged emergence of sensitivity could be due to
restricted phonetic space and input variations but suggests
the possibility of a different developmental trajectory. The
current study contributes scarcely represented
Korean-learning infants' phonetic discrimination data to the
speech development field.},
Doi = {10.1111/desc.13422},
Key = {fds371461}
}
%% Meade, Christina S.
@article{fds372971,
Author = {Towe, SL and Tang, R and Gibson, MJ and Zhang, AR and Meade,
CS},
Title = {Longitudinal changes in neurocognitive performance related
to drug use intensity in a sample of persons with and
without HIV who use illicit stimulants.},
Journal = {Drug Alcohol Depend},
Volume = {251},
Pages = {110923},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1016/j.drugalcdep.2023.110923},
Abstract = {BACKGROUND: Illicit stimulant use remains a public health
concern that has been associated with multiple adverse
outcomes, including cognitive deficits. The effects of
stimulant use on cognition may be particularly deleterious
in persons with HIV. Stimulant use intensity may be an
important factor in the magnitude of observed deficits over
time. METHODS: We completed neurocognitive testing in a
sample of people who use stimulants with (n = 84) and
without HIV (n = 123) at baseline and up to 4 follow-up time
points over approximately 1 year. Participants reported on
substance use at each visit, including frequency of use and
stimulant dependence. Mixed effects models examined the
relationship between stimulant-related factors and
neurocognitive function over time. RESULTS: Participants
were mostly male (57%), African American (86%), and 47.41
years old on average. All participants actively used
stimulants at enrollment and use remained prevalent
throughout the follow-up period, with an average of ≥24
days of use in the past 90 days at all time points.
Retention was excellent, with 86% completing all 4 follow-up
assessments. Mixed effects models showed that stimulant
dependence was associated with lower neurocognitive
performance independent of HIV status (p = 0.002), whereas
frequency of use had a greater negative impact on
performance in participants with HIV compared to those
without HIV (p = 0.045). CONCLUSIONS: Our key finding is
that stimulant-related factors are associated with
neurocognitive performance over time, but in complex ways.
These findings have important implications for harm
reduction approaches, particularly those that target
cognitive function.},
Doi = {10.1016/j.drugalcdep.2023.110923},
Key = {fds372971}
}
@article{fds372606,
Author = {Meade, CS and Bell, RP and Towe, SL and Lascola, CD and Al-Khalil, K and Gibson, MJ},
Title = {Cocaine use is associated with cerebral white matter
hyperintensities in HIV disease.},
Journal = {Ann Clin Transl Neurol},
Volume = {10},
Number = {9},
Pages = {1633-1646},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1002/acn3.51854},
Abstract = {BACKGROUND: White matter hyperintensities (WMH), a marker of
cerebral small vessel disease and predictor of cognitive
decline, are observed at higher rates in persons with HIV
(PWH). The use of cocaine, a potent central nervous system
stimulant, is disproportionately common in PWH and may
contribute to WMH. METHODS: The sample included of 110 PWH
on antiretroviral therapy. Fluid-attenuated inversion
recovery (FLAIR) and T1-weighted anatomical MRI scans were
collected, along with neuropsychological testing. FLAIR
images were processed using the Lesion Segmentation Toolbox.
A hierarchical regression model was run to investigate
predictors of WMH burden [block 1: demographics; block 2:
cerebrovascular disease (CVD) risk; block 3: lesion burden].
RESULTS: The sample was 20% female and 79% African American
with a mean age of 45.37. All participants had persistent
HIV viral suppression, and the median CD4+ T-cell count was
750. Nearly a third (29%) currently used cocaine regularly,
with an average of 23.75 (SD = 20.95) days in the past
90. In the hierarchical linear regression model, cocaine use
was a significant predictor of WMH burden (β = .28).
WMH burden was significantly correlated with poorer
cognitive function (r = -0.27). Finally, higher WMH
burden was significantly associated with increased serum
concentrations of interferon-γ-inducible protein 10 (IP-10)
but lower concentrations of myeloperoxidase (MPO); however,
these markers did not differ by COC status. CONCLUSIONS: WMH
burden is associated with poorer cognitive performance in
PWH. Cocaine use and CVD risk independently contribute to
WMH, and addressing these conditions as part of HIV care may
mitigate brain injury underlying neurocognitive
impairment.},
Doi = {10.1002/acn3.51854},
Key = {fds372606}
}
@article{fds369884,
Author = {Al-Khalil, K and Towe, SL and Ikner, TP and Meade,
CS},
Title = {HIV viremia contributes to neurocognitive impairments in
persons who use cocaine.},
Journal = {Journal of neurovirology},
Volume = {29},
Number = {3},
Pages = {331-336},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1007/s13365-022-01100-4},
Abstract = {Persons with HIV (PWH) who use illicit drugs are at elevated
risk for neurocognitive impairment (NCI). This study
investigated the effects of HIV disease and HIV viremia on
NCI among adults who use cocaine. PWH who were not
virologically suppressed showed greater global deficits
compared to participants with HIV viral suppression and
HIV-negative participants, but no differences emerged
between the latter two groups. These findings highlight the
adverse effects of poorly controlled HIV disease on NCI,
beyond the independent effects of cocaine on cognition, and
underscore the importance of strengthening the HIV care
continuum for persons who use cocaine.},
Doi = {10.1007/s13365-022-01100-4},
Key = {fds369884}
}
@article{fds369721,
Author = {Al-Khalil, K and Bell, RP and Towe, SL and Gadde, S and Burke, E and Meade,
CS},
Title = {Cortico-striatal networking deficits associated with
advanced HIV disease and cocaine use.},
Journal = {Journal of neurovirology},
Volume = {29},
Number = {2},
Pages = {167-179},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1007/s13365-023-01120-8},
Abstract = {Cocaine use is disproportionately prevalent in people with
HIV (PWH) and is known to potentiate HIV neuropathogenesis.
As both HIV and cocaine have well-documented
cortico-striatal effects, PWH who use cocaine and have a
history of immunosuppression may exhibit greater FC deficits
compared to PWH without these conditions. However, research
investigating the legacy effects of HIV immunosuppression
(i.e., a history of AIDS) on cortico-striatal functional
connectivity (FC) in adults with and without cocaine use is
sparse. Resting-state functional magnetic resonance imaging
(fMRI) and neuropsychological assessment data from 273
adults were analyzed to examine FC in relation to HIV
disease: HIV-negative (n = 104), HIV-positive with nadir
CD4 ≥ 200 (n = 96), HIV-positive with nadir
CD4 < 200 (AIDS; n = 73), and cocaine use (83 COC
and 190 NON). Using independent component analysis/dual
regression, FC was assessed between the basal ganglia
network (BGN) and five cortical networks: dorsal attention
network (DAN), default mode network, left executive network,
right executive network, and salience network. There were
significant interaction effects such that AIDS-related
BGN-DAN FC deficits emerged in COC but not in NON
participants. Independent of HIV, cocaine effects emerged in
FC between the BGN and executive networks. Disruption of
BGN-DAN FC in AIDS/COC participants is consistent with
cocaine potentiation of neuro-inflammation and may be
indicative of legacy HIV immunosuppressive effects. The
current study bolsters previous findings linking HIV and
cocaine use with cortico-striatal networking deficits.
Future research should consider the effects of the duration
of HIV immunosuppression and early treatment
initiation.},
Doi = {10.1007/s13365-023-01120-8},
Key = {fds369721}
}
@article{fds370065,
Author = {O'Connor, EE and Sullivan, EV and Chang, L and Hammoud, DA and Wilson,
TW and Ragin, AB and Meade, CS and Coughlin, J and Ances,
BM},
Title = {Imaging of Brain Structural and Functional Effects in People
With Human Immunodeficiency Virus.},
Journal = {The Journal of infectious diseases},
Volume = {227},
Number = {Suppl 1},
Pages = {S16-S29},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1093/infdis/jiac387},
Abstract = {Before the introduction of antiretroviral therapy, human
immunodeficiency virus (HIV) infection was often accompanied
by central nervous system (CNS) opportunistic infections and
HIV encephalopathy marked by profound structural and
functional alterations detectable with neuroimaging.
Treatment with antiretroviral therapy nearly eliminated CNS
opportunistic infections, while neuropsychiatric impairment
and peripheral nerve and organ damage have persisted among
virally suppressed people with HIV (PWH), suggesting ongoing
brain injury. Neuroimaging research must use methods
sensitive for detecting subtle HIV-associated brain
structural and functional abnormalities, while allowing for
adjustments for potential confounders, such as age, sex,
substance use, hepatitis C coinfection, cardiovascular risk,
and others. Here, we review existing and emerging
neuroimaging tools that demonstrated promise in detecting
markers of HIV-associated brain pathology and explore
strategies to study the impact of potential confounding
factors on these brain measures. We emphasize neuroimaging
approaches that may be used in parallel to gather
complementary information, allowing efficient detection and
interpretation of altered brain structure and function
associated with suboptimal clinical outcomes among virally
suppressed PWH. We examine the advantages of each imaging
modality and systematic approaches in study design and
analysis. We also consider advantages of combining
experimental and statistical control techniques to improve
sensitivity and specificity of biotype identification and
explore the costs and benefits of aggregating data from
multiple studies to achieve larger sample sizes, enabling
use of emerging methods for combining and analyzing large,
multifaceted data sets. Many of the topics addressed in this
article were discussed at the National Institute of Mental
Health meeting "Biotypes of CNS Complications in People
Living with HIV," held in October 2021, and are part of
ongoing research initiatives to define the role of
neuroimaging in emerging alternative approaches to
identifying biotypes of CNS complications in PWH. An outcome
of these considerations may be the development of a common
neuroimaging protocol available for researchers to use in
future studies examining neurological changes in the brains
of PWH.},
Doi = {10.1093/infdis/jiac387},
Key = {fds370065}
}
@article{fds367997,
Author = {Murdoch, DM and Barfield, R and Chan, C and Towe, SL and Bell, RP and Volkheimer, A and Choe, J and Hall, SA and Berger, M and Xie, J and Meade,
CS},
Title = {Neuroimaging and immunological features of neurocognitive
function related to substance use in people with
HIV.},
Journal = {J Neurovirol},
Volume = {29},
Number = {1},
Pages = {78-93},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1007/s13365-022-01102-2},
Abstract = {This study sought to identify neuroimaging and immunological
factors associated with substance use and that contribute to
neurocognitive impairment (NCI) in people with HIV (PWH). We
performed cross-sectional immunological phenotyping,
neuroimaging, and neurocognitive testing on virally
suppressed PWH in four substance groups: cocaine only users
(COC), marijuana only users (MJ), dual users (Dual), and
Non-users. Participants completed substance use assessments,
multimodal MRI brain scan, neuropsychological testing, and
blood and CSF sampling. We employed a two-stage analysis of
305 possible biomarkers of cognitive function associated
with substance use. Feature reduction (Kruskal Wallis
p-value < 0.05) identified 53 biomarkers associated with
substance use (22 MRI and 31 immunological) for model
inclusion along with clinical and demographic variables. We
employed eXtreme Gradient Boosting (XGBoost) with these
markers to predict cognitive function (global T-score).
SHapley Additive exPlanations (SHAP) values were calculated
to rank features for impact on model output and NCI.
Participants were 110 PWH with sustained HIV viral
suppression (33 MJ, 12 COC, 22 Dual, and 43 Non-users). The
ten highest ranking biomarkers for predicting global T-score
were 4 neuroimaging biomarkers including functional
connectivity, gray matter volume, and white matter
integrity; 5 soluble biomarkers (plasma glycine, alanine,
lyso-phosphatidylcholine (lysoPC) aC17.0,
hydroxy-sphingomyelin (SM.OH) C14.1, and
phosphatidylcholinediacyl (PC aa) C28.1); and 1 clinical
variable (nadir CD4 count). The results of our machine
learning model suggest that substance use may indirectly
contribute to NCI in PWH through both metabolomic and
neuropathological mechanisms.},
Doi = {10.1007/s13365-022-01102-2},
Key = {fds367997}
}
@article{fds369722,
Author = {Bell, RP and Towe, SL and Al-Khalil, K and Gibson, M and Nadeem, T and Meade, CS},
Title = {Additive cortical gray matter deficits in people living with
HIV who use cocaine.},
Journal = {Journal of neurovirology},
Volume = {29},
Number = {1},
Pages = {53-64},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1007/s13365-023-01111-9},
Abstract = {Cocaine use, which is disproportionately common in people
living with HIV (PWH), is known to have neurotoxic effects
that may exacerbate HIV neuropathogenesis. While both
cocaine use and HIV disease are independently associated
with deficits in gray matter (GM) volume, the additive
effect of cocaine use to HIV disease on GM volume has not
been explored. Here, we investigated subcortical and
cortical brain volume differences between four groups of
individuals with and without HIV disease and/or cocaine use.
Participants also completed a comprehensive
neuropsychological testing battery, and HIV disease
characteristics were recorded. Within subcortical regions,
cocaine use was independently associated with higher volume
in the dorsal striatum and pallidum, while HIV disease was
associated with lower volume in the nucleus accumbens and
thalamus. For cortical regions, there was an additive effect
of cocaine use on HIV disease in parietal and occipital lobe
volume with PWH who used cocaine displaying the lowest GM
volume. Within regions that differed between groups, higher
neurocognitive function was positively associated with
thalamic, nucleus accumbens, dorsal striatum, and occipital
lobe volume. For regions that showed a significant main
effect of HIV disease, lower nadir CD4 + T cell count
was associated with lower nucleus accumbens and occipital
lobe volume. Lower current CD4 + T cell count was
associated with lower occipital lobe volume. These results
suggest that PWH who use cocaine are at greater risk for
cortical atrophy than cocaine use or HIV disease
alone.},
Doi = {10.1007/s13365-023-01111-9},
Key = {fds369722}
}
@article{fds369723,
Author = {Li, X and Towe, SL and Bell, RP and Jiang, R and Hall, SA and Calhoun, VD and Meade, CS and Sui, J},
Title = {The Individualized Prediction of Neurocognitive Function in
People Living with HIV Based on Clinical and Multimodal
Connectome Data.},
Journal = {IEEE journal of biomedical and health informatics},
Volume = {PP},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1109/jbhi.2023.3240508},
Abstract = {Neurocognitive impairment continues to be common comorbidity
for people living with HIV (PLWH). Given the chronic nature
of HIV disease, identifying reliable biomarkers of these
impairments is essential to advance our understanding of the
underlying neural foundation and facilitate screening and
diagnosis in clinical care. While neuroimaging provides
immense potential for such biomarkers, to date,
investigations in PLWH have been mostly limited to either
univariate mass techniques or a single neuroimaging
modality. In the present study, connectome-based predictive
modeling (CPM) was proposed to predict individual
differences of cognitive functioning in PLWH, using
resting-state functional connectivity (FC), white matter
structural connectivity (SC), and clinical relevant
measures. We also adopted an efficient feature selection
approach to identify the most predictive features, which
achieved an optimal prediction accuracy of r = 0.61 in the
discovery dataset (n = 102) and r = 0.45 in an independent
validation HIV cohort (n = 88). Two brain templates and nine
distinct prediction models were also tested for better
modeling generalizability. Results show that combining
multimodal FC and SC features enabled higher prediction
accuracy of cognitive scores in PLWH, while adding clinical
and demographic metrics may further improve the prediction
by introducing complementary information, which may help
better evaluate the individual-level cognitive performance
in PLWH.},
Doi = {10.1109/jbhi.2023.3240508},
Key = {fds369723}
}
%% Moffitt, Terrie E.
@article{fds376145,
Author = {Whitman, ET and Ryan, CP and Abraham, WC and Addae, A and Corcoran, DL and Elliott, ML and Hogan, S and Ireland, D and Keenan, R and Knodt, AR and Melzer, TR and Poulton, R and Ramrakha, S and Sugden, K and Williams,
BS and Zhou, J and Hariri, AR and Belsky, DW and Moffitt, TE and Caspi, A and Alzheimer’s Disease Neuroimaging Initiative},
Title = {A blood biomarker of the pace of aging is associated with
brain structure: replication across three
cohorts.},
Journal = {Neurobiology of aging},
Volume = {136},
Pages = {23-33},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1016/j.neurobiolaging.2024.01.008},
Abstract = {Biological aging is the correlated decline of multi-organ
system integrity central to the etiology of many age-related
diseases. A novel epigenetic measure of biological aging,
DunedinPACE, is associated with cognitive dysfunction,
incident dementia, and mortality. Here, we tested for
associations between DunedinPACE and structural MRI
phenotypes in three datasets spanning midlife to advanced
age: the Dunedin Study (age=45 years), the Framingham Heart
Study Offspring Cohort (mean age=63 years), and the
Alzheimer's Disease Neuroimaging Initiative (mean age=75
years). We also tested four additional epigenetic measures
of aging: the Horvath clock, the Hannum clock, PhenoAge, and
GrimAge. Across all datasets (total N observations=3380;
total N individuals=2322), faster DunedinPACE was associated
with lower total brain volume, lower hippocampal volume,
greater burden of white matter microlesions, and thinner
cortex. Across all measures, DunedinPACE and GrimAge had the
strongest and most consistent associations with brain
phenotypes. Our findings suggest that single timepoint
measures of multi-organ decline such as DunedinPACE could be
useful for gauging nervous system health.},
Doi = {10.1016/j.neurobiolaging.2024.01.008},
Key = {fds376145}
}
@article{fds371370,
Author = {Theadom, A and Barker-Collo, S and Parag, V and Caspi, A and Moffitt,
TE and Hogan, S and Ramrakha, S and Poulton, R},
Title = {Mild Traumatic Brain Injury Does Not Significantly Affect
Midlife Cognitive Functioning Within the General Population:
Findings From a Prospective Longitudinal Birth Cohort
Study.},
Journal = {The Journal of head trauma rehabilitation},
Volume = {39},
Number = {2},
Pages = {E70-E82},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1097/htr.0000000000000875},
Abstract = {<h4>Objective</h4>To determine whether differences exist in
mid-adulthood cognitive functioning in people with and
without history of mild traumatic brain injury
(mTBI).<h4>Setting</h4>Community-based study.<h4>Participants</h4>People
born between April 1, 1972, and March 31, 1973, recruited
into the Dunedin Multidisciplinary Health and Development
Longitudinal Study, who completed neuropsychological
assessments in mid-adulthood. Participants who had
experienced a moderate or severe TBI or mTBI in the past 12
months were excluded.<h4>Design</h4>Longitudinal,
prospective, observational study.<h4>Main measures</h4>Data
were collected on sociodemographic characteristics, medical
history, childhood cognition (between 7 and 11 years), and
alcohol and substance dependence (from 21 years of age).
mTBI history was determined from accident and medical
records (from birth to 45 years of age). Participants were
classified as having 1 mTBI and more in their lifetime or no
mTBI. The Wechsler Adult Intelligence Scale (WAIS-IV) and
Trail Making Tests A and B (between 38 and 45 years of age)
were used to assess cognitive functioning. T tests and
effect sizes were used to identify any differences on
cognitive functioning domains between the mTBI and no mTBI
groups. Regression models explored the relative contribution
of number of mTBIs and age of first mTBI and
sociodemographic/lifestyle variables on cognitive
functioning.<h4>Results</h4>Of the 885 participants, 518
(58.5%) had experienced at least 1 mTBI over their lifetime,
with a mean number of 2.5 mTBIs. The mTBI group had
significantly slower processing speed ( P < .01, d = 0.23)
in mid-adulthood than the no TBI controls, with a medium
effect size. However, the relationship no longer remained
significant after controlling for childhood cognition,
sociodemographic and lifestyle factors. No significant
differences were observed for overall intelligence, verbal
comprehension, perceptual reasoning, working memory,
attention, or cognitive flexibility. Childhood cognition was
not linked to likelihood of sustaining mTBI later in
life.<h4>Conclusion</h4>mTBI histories in the general
population were not associated with lower cognitive
functioning in mid-adulthood once sociodemographic and
lifestyle factors were taken into account.},
Doi = {10.1097/htr.0000000000000875},
Key = {fds371370}
}
@article{fds376781,
Author = {Reuben, A and Richmond-Rakerd, LS and Milne, B and Shah, D and Pearson,
A and Hogan, S and Ireland, D and Keenan, R and Knodt, AR and Melzer, T and Poulton, R and Ramrakha, S and Whitman, ET and Hariri, AR and Moffitt,
TE and Caspi, A},
Title = {Dementia, dementia's risk factors and premorbid brain
structure are concentrated in disadvantaged areas: National
register and birth-cohort geographic analyses.},
Journal = {Alzheimer's & dementia : the journal of the Alzheimer's
Association},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1002/alz.13727},
Abstract = {<h4>Introduction</h4>Dementia risk may be elevated in
socioeconomically disadvantaged neighborhoods. Reasons for
this remain unclear, and this elevation has yet to be shown
at a national population level.<h4>Methods</h4>We tested
whether dementia was more prevalent in disadvantaged
neighborhoods across the New Zealand population (N = 1.41
million analytic sample) over a 20-year observation. We then
tested whether premorbid dementia risk factors and
MRI-measured brain-structure antecedents were more prevalent
among midlife residents of disadvantaged neighborhoods in a
population-representative NZ-birth-cohort (N = 938
analytic sample).<h4>Results</h4>People residing in
disadvantaged neighborhoods were at greater risk of dementia
(HR per-quintile-disadvantage-increase = 1.09, 95%
confidence interval [CI]:1.08-1.10) and, decades before
clinical endpoints typically emerge, evidenced elevated
dementia-risk scores (CAIDE, LIBRA, Lancet, ANU-ADRI,
DunedinARB; β's 0.31-0.39) and displayed
dementia-associated brain structural deficits and cognitive
difficulties/decline.<h4>Discussion</h4>Disadvantaged
neighborhoods have more residents with dementia, and decades
before dementia is diagnosed, residents have more
dementia-risk factors and brain-structure antecedents.
Whether or not neighborhoods causally influence risk, they
may offer scalable opportunities for primary dementia
prevention.},
Doi = {10.1002/alz.13727},
Key = {fds376781}
}
@article{fds376782,
Author = {Graf, GHJ and Aiello, AE and Caspi, A and Kothari, M and Liu, H and Moffitt, TE and Muennig, PA and Ryan, CP and Sugden, K and Belsky,
DW},
Title = {Educational Mobility, Pace of Aging, and Lifespan Among
Participants in the Framingham Heart Study.},
Journal = {JAMA network open},
Volume = {7},
Number = {3},
Pages = {e240655},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1001/jamanetworkopen.2024.0655},
Abstract = {<h4>Importance</h4>People who complete more education live
longer lives with better health. New evidence suggests that
these benefits operate through a slowed pace of biological
aging. If so, measurements of the pace of biological aging
could offer intermediate end points for studies of how
interventions to promote education will affect healthy
longevity.<h4>Objective</h4>To test the hypothesis that
upward educational mobility is associated with a slower pace
of biological aging and increased longevity.<h4>Design,
setting, and participants</h4>This prospective cohort study
analyzed data from 3 generations of participants in the
Framingham Heart Study: (1) the original cohort, enrolled
beginning in 1948; (2) the Offspring cohort, enrolled
beginning in 1971; and (3) the Gen3 cohort, enrolled
beginning in 2002. A 3-generation database was constructed
to quantify intergenerational educational mobility. Mobility
data were linked with blood DNA-methylation data collected
from the Offspring cohort in 2005 to 2008 (n = 1652) and
the Gen3 cohort in 2009 to 2011 (n = 1449). Follow-up is
ongoing. Data analysis was conducted from June 2022 to
November 2023 using data obtained from the National
Institutes of Health database of Genotypes and Phenotypes
(dbGaP).<h4>Exposure</h4>Educational mobility was measured
by comparing participants' educational outcomes with those
of their parents.<h4>Main outcomes and measures</h4>The pace
of biological aging was measured from whole-blood
DNA-methylation data using the DunedinPACE epigenetic clock.
For comparison purposes, the analysis was repeated using 4
other epigenetic clocks. Survival follow-up was conducted
through 2019.<h4>Results</h4>This study analyzed data from
3101 participants from the Framingham Heart Study; 1652 were
in the Offspring cohort (mean [SD] age, 65.57 [9.22] years;
764 [46.2%] male) and 1449 were in the Gen3 cohort (mean
[SD] age, 45.38 [7.83] years; 691 [47.7%] male).
Participants who were upwardly mobile in educational terms
tended to have slower pace of aging in later life
(r = -0.18 [95% CI, -0.23 to -0.13]; P < .001). This
pattern of association was similar across generations and
held in within-family sibling comparisons. There were 402
Offspring cohort participants who died over the follow-up
period. Upward educational mobility was associated with
lower mortality risk (hazard ratio, 0.89 [95% CI, 0.81 to
0.98]; P = .01). Slower pace of aging accounted for
approximately half of this association.<h4>Conclusions and
relevance</h4>This cohort study's findings support the
hypothesis that interventions to promote educational
attainment may slow the pace of biological aging and promote
longevity. Epigenetic clocks have potential as near-term
outcome measures of intervention effects on healthy aging.
Experimental evidence is needed to confirm
findings.},
Doi = {10.1001/jamanetworkopen.2024.0655},
Key = {fds376782}
}
@article{fds368586,
Author = {Guiney, H and Caspi, A and Ambler, A and Belsky, J and Kokaua, J and Broadbent, J and Cheyne, K and Dickson, N and Hancox, RJ and Harrington,
H and Hogan, S and Ramrakha, S and Righarts, A and Thomson, WM and Moffitt,
TE and Poulton, R},
Title = {Childhood sexual abuse and pervasive problems across
multiple life domains: Findings from a five-decade
study.},
Journal = {Development and psychopathology},
Volume = {36},
Number = {1},
Pages = {219-235},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1017/s0954579422001146},
Abstract = {The aim of this study was to use longitudinal
population-based data to examine the associations between
childhood sexual abuse (CSA) and risk for adverse outcomes
in multiple life domains across adulthood. In 937
individuals followed from birth to age 45y, we assessed
associations between CSA (retrospectively reported at age
26y) and the experience of 22 adverse outcomes in seven
domains (physical, mental, sexual, interpersonal, economic,
antisocial, multi-domain) from young adulthood to midlife
(26 to 45y). Analyses controlled for sex, socioeconomic
status, prospectively reported child harm and household
dysfunction adverse childhood experiences, and adult sexual
assault, and considered different definitions of CSA. After
adjusting for confounders, CSA survivors were more likely
than their peers to experience internalizing, externalizing,
and thought disorders, suicide attempts, health risk
behaviors, systemic inflammation, poor oral health, sexually
transmitted diseases, high-conflict relationships, benefit
use, financial difficulties, antisocial behavior, and
cumulative problems across multiple domains in adulthood. In
sum, CSA was associated with multiple persistent problems
across adulthood, even after adjusting for confounding life
stressors, and the risk for particular problems incremented
with CSA severity. The higher risk for most specific
problems was small to moderate, but the cumulative long-term
effects across multiple domains reflect considerable
individual and societal burden.},
Doi = {10.1017/s0954579422001146},
Key = {fds368586}
}
@article{fds376783,
Author = {Bryan, BT and Thompson, KN and Goldman-Mellor, S and Moffitt, TE and Odgers, CL and So, SLS and Uddin Rahman and M and Wertz, J and Matthews, T and Arseneault, L},
Title = {The socioeconomic consequences of loneliness: Evidence from
a nationally representative longitudinal study of young
adults.},
Journal = {Social science & medicine (1982)},
Pages = {116697},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1016/j.socscimed.2024.116697},
Abstract = {The negative health consequences of loneliness have led to
increasing concern about the economic cost of loneliness in
recent years. Loneliness may also incur an economic burden
more directly, by impacting socioeconomic position. Much of
the research to date has focused on employment status which
may not fully capture socioeconomic position and has relied
on cross-sectional data, leaving questions around the
robustness of the association and reverse causation. The
present study used longitudinal data to test prospective
associations between loneliness and multiple indicators of
social position in young adulthood, specifically, whether
participants who were lonelier at age 12 were more likely to
be out of employment, education and training (NEET) and
lower on employability and subjective social status as young
adults. The data were drawn from the Environmental Risk
(E-Risk) Longitudinal Twin Study, a birth cohort of 2,232
individuals born in England and Wales during 1994-1995.
Loneliness and subjective social status were measured at
ages 12, 18 and 26. Employability and NEET status were
assessed at age 18. Findings indicate that greater
loneliness at age 12 was prospectively associated with
reduced employability and lower social status in young
adulthood. The association between loneliness and lower
social status in young adulthood was robust when controlling
for a range of confounders using a sibling-control design.
Results also indicate that loneliness is unidirectionally
associated with reduced subjective social status across
adolescence and young adulthood. Overall, our findings
suggest that loneliness may have direct costs to the economy
resulting from reduced employability and social position,
underlining the importance of addressing loneliness early in
life.},
Doi = {10.1016/j.socscimed.2024.116697},
Key = {fds376783}
}
@article{fds375488,
Author = {Bourassa, KJ and Garrett, ME and Caspi, A and Dennis, M and Hall, KS and Moffitt, TE and Taylor, GA and VA Mid Atlantic MIRECC Workgroup, and Ashley-Koch, AE and Beckham, JC and Kimbrel, NA},
Title = {Posttraumatic stress disorder, trauma, and accelerated
biological aging among post-9/11 veterans.},
Journal = {Transl Psychiatry},
Volume = {14},
Number = {1},
Pages = {4},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1038/s41398-023-02704-y},
Abstract = {People who experience trauma and develop posttraumatic
stress disorder (PTSD) are at increased risk for poor
health. One mechanism that could explain this risk is
accelerated biological aging, which is associated with the
accumulation of chronic diseases, disability, and premature
mortality. Using data from 2309 post-9/11 United States
military veterans who participated in the VISN 6 MIRECC's
Post-Deployment Mental Health Study, we tested whether PTSD
and trauma exposure were associated with accelerated rate of
biological aging, assessed using a validated DNA methylation
(DNAm) measure of epigenetic aging-DunedinPACE. Veterans
with current PTSD were aging faster than those who did not
have current PTSD, β = 0.18, 95% CI [0.11, 0.27],
p < .001. This effect represented an additional 0.4
months of biological aging each year. Veterans were also
aging faster if they reported more PTSD symptoms,
β = 0.13, 95% CI [0.09, 0.16], p < 0.001, or higher
levels of trauma exposure, β = 0.09, 95% CI [0.05,
0.13], p < 0.001. Notably, veterans with past PTSD were
aging more slowly than those with current PTSD,
β = -0.21, 95% CI [-0.35, -0.07], p = .003. All
reported results accounted for age, gender, self-reported
race/ethnicity, and education, and remained when controlling
for smoking. Our findings suggest that an accelerated rate
of biological aging could help explain how PTSD contributes
to poor health and highlights the potential benefits of
providing efficacious treatment to populations at increased
risk of trauma and PTSD.},
Doi = {10.1038/s41398-023-02704-y},
Key = {fds375488}
}
@article{fds370883,
Author = {Caspi, A and Houts, RM and Fisher, HL and Danese, A and Moffitt,
TE},
Title = {The general factor of psychopathology (p): Choosing among
competing models and interpreting p.},
Journal = {Clinical psychological science : a journal of the
Association for Psychological Science},
Volume = {12},
Number = {1},
Pages = {53-82},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1177/21677026221147872},
Abstract = {Over the past 10 years, the general factor of
psychopathology, p, has attracted interest and scrutiny. We
review the history of the idea that all mental disorders
share something in common, p; how we arrived at this idea;
and how it became conflated with a statistical
representation, the Bi-Factor Model. We then leverage the
Environmental Risk (E-Risk) longitudinal twin study to
examine the properties and nomological network of different
statistical representations of p. We find that p performed
similarly regardless of how it was modelled, suggesting that
if the sample and content are the same the resulting p
factor will be similar. We suggest that the meaning of p is
not to be found by dueling over statistical models but by
conducting well-specified criterion-validation studies and
developing new measurement approaches. We outline new
directions to refresh research efforts to uncover what all
mental disorders have in common.},
Doi = {10.1177/21677026221147872},
Key = {fds370883}
}
@article{fds374321,
Author = {Matthews, T and Rasmussen, LJH and Ambler, A and Danese, A and Eugen-Olsen, J and Fancourt, D and Fisher, HL and Iversen, KK and Schultz, M and Sugden, K and Williams, B and Caspi, A and Moffitt,
TE},
Title = {Social isolation, loneliness, and inflammation: A
multi-cohort investigation in early and mid-adulthood.},
Journal = {Brain, behavior, and immunity},
Volume = {115},
Pages = {727-736},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.bbi.2023.11.022},
Abstract = {Social isolation and loneliness have been associated with
poor health and increased risk for mortality, and
inflammation might explain this link. We used data from the
Danish TRIAGE Study of acutely admitted medical patients
(N = 6,144, mean age 60 years), and from two
population-representative birth cohorts: the New Zealand
Dunedin Longitudinal Study (N = 881, age 45) and the UK
Environmental Risk (E-Risk) Longitudinal Twin Study
(N = 1448, age 18), to investigate associations of social
isolation with three markers of systemic inflammation:
C-reactive protein (CRP), interleukin-6 (IL-6), and a newer
inflammation marker, soluble urokinase plasminogen activator
receptor (suPAR), which is thought to index systemic chronic
inflammation. In the TRIAGE Study, socially isolated
patients (those living alone) had significantly higher
median levels of suPAR (but not CRP or IL-6) compared with
patients not living by themselves. Social isolation
prospectively measured in childhood was longitudinally
associated with higher CRP, IL-6, and suPAR levels in
adulthood (at age 45 in the Dunedin Study and age 18 in the
E-Risk Study), but only suPAR remained associated after
controlling for covariates. Dunedin Study participants who
reported loneliness at age 38 or age 45 had elevated suPAR
at age 45. In contrast, E-Risk Study participants reporting
loneliness at age 18 did not show any elevated markers of
inflammation. In conclusion, social isolation was robustly
associated with increased inflammation in adulthood, both in
medical patients and in the general population. It was
associated in particular with systemic chronic inflammation,
evident from the consistently stronger associations with
suPAR than other inflammation biomarkers.},
Doi = {10.1016/j.bbi.2023.11.022},
Key = {fds374321}
}
@article{fds375489,
Author = {Brennan, GM and Moffitt, TE and Bourassa, KJ and Harrington, HL and Hogan, S and Houts, RM and Poulton, R and Ramrakha, S and Caspi,
A},
Title = {The Continuity of Adversity: Negative Emotionality Links
Early Life Adversity With Adult Stressful Life
Events},
Journal = {Clinical Psychological Science},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1177/21677026231220337},
Abstract = {Adversity that exhibits continuity across the life course
has long-term detrimental effects on physical and mental
health. Using 920 participants from the Dunedin Study, we
tested the following hypotheses: (a) Children (ages 3–15)
who experienced adversity would also tend to experience
adversity in adulthood (ages 32–45), and (2) interim
personality traits in young adulthood (ages 18–26) would
help account for this longitudinal association. Children who
experienced more adversity tended to also experience more
stressful life events as adults, β = 0.11, 95% confidence
interval [CI] = [0.04, 0.18], p =.002. Negative
emotionality—particularly its subfacet alienation,
characterized by mistrust of others—helped explain this
childhood-to-midlife association (indirect effect: β =
0.06, 95% CI = [0.04, 0.09], p <.001). Results were robust
to adjustment for sex, socioeconomic origins, childhood IQ,
preschool temperament, and other young-adult personality
traits. Prevention of early life adversity and treatment of
young-adult negative emotionality may reduce vulnerability
to later life stress and thereby promote the health of aging
adults.},
Doi = {10.1177/21677026231220337},
Key = {fds375489}
}
@article{fds371008,
Author = {Brennan, GM and Moffitt, TE and Ambler, A and Harrington, H and Hogan,
S and Houts, RM and Mani, R and Poulton, R and Ramrakha, S and Caspi,
A},
Title = {Tracing the origins of midlife despair: association of
psychopathology during adolescence with a syndrome of
despair-related maladies at midlife.},
Journal = {Psychological medicine},
Volume = {53},
Number = {16},
Pages = {7569-7580},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1017/s0033291723001320},
Abstract = {<h4>Background</h4>Midlife adults are experiencing a crisis
of deaths of despair (i.e. deaths from suicide, drug
overdose, and alcohol-related liver disease). We tested the
hypothesis that a syndrome of despair-related maladies at
midlife is preceded by psychopathology during
adolescence.<h4>Methods</h4>Participants are members of a
representative cohort of 1037 individuals born in Dunedin,
New Zealand in 1972-73 and followed to age 45 years, with
94% retention. Adolescent mental disorders were assessed in
three diagnostic assessments at ages 11, 13, and 15 years.
Indicators of despair-related maladies across four domains -
suicidality, substance misuse, sleep problems, and pain -
were assessed at age 45 using multi-modal measures including
self-report, informant-report, and national register
data.<h4>Results</h4>We identified and validated a syndrome
of despair-related maladies at midlife involving
suicidality, substance misuse, sleep problems, and pain.
Adults who exhibited a more severe syndrome of
despair-related maladies at midlife tended to have had
early-onset emotional and behavioral disorders [<i>β</i> =
0.23, 95% CI (0.16-0.30), <i>p</i> < 0.001], even after
adjusting for sex, childhood SES, and childhood IQ. A more
pronounced midlife despair syndrome was observed among
adults who, as adolescents, were diagnosed with a greater
number of mental disorders [<i>β</i> = 0.26, 95% CI
(0.19-0.33), <i>p</i> < 0.001]. Tests of diagnostic
specificity revealed that associations generalized across
different adolescent mental disorders.<h4>Conclusions</h4>Midlife
adults who exhibited a more severe syndrome of
despair-related maladies tended to have had psychopathology
as adolescents. Prevention and treatment of adolescent
psychopathology may mitigate despair-related maladies at
midlife and ultimately reduce deaths of despair.},
Doi = {10.1017/s0033291723001320},
Key = {fds371008}
}
@article{fds373506,
Author = {Knodt, AR and Elliott, ML and Whitman, ET and Winn, A and Addae, A and Ireland, D and Poulton, R and Ramrakha, S and Caspi, A and Moffitt, TE and Hariri, AR},
Title = {Test-retest reliability and predictive utility of a
macroscale principal functional connectivity
gradient.},
Journal = {Human brain mapping},
Volume = {44},
Number = {18},
Pages = {6399-6417},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1002/hbm.26517},
Abstract = {Mapping individual differences in brain function has been
hampered by poor reliability as well as limited
interpretability. Leveraging patterns of brain-wide
functional connectivity (FC) offers some promise in this
endeavor. In particular, a macroscale principal FC gradient
that recapitulates a hierarchical organization spanning
molecular, cellular, and circuit level features along a
sensory-to-association cortical axis has emerged as both a
parsimonious and interpretable measure of individual
differences in behavior. However, the measurement
reliabilities of this FC gradient have not been fully
evaluated. Here, we assess the reliabilities of both global
and regional principal FC gradient measures using
test-retest data from the young adult Human Connectome
Project (HCP-YA) and the Dunedin Study. Analyses revealed
that the reliabilities of principal FC gradient measures
were (1) consistently higher than those for traditional
edge-wise FC measures, (2) higher for FC measures derived
from general FC (GFC) in comparison with resting-state FC,
and (3) higher for longer scan lengths. We additionally
examined the relative utility of these principal FC gradient
measures in predicting cognition and aging in both datasets
as well as the HCP-aging dataset. These analyses revealed
that regional FC gradient measures and global gradient range
were significantly associated with aging in all three
datasets, and moderately associated with cognition in the
HCP-YA and Dunedin Study datasets, reflecting contractions
and expansions of the cortical hierarchy, respectively.
Collectively, these results demonstrate that measures of the
principal FC gradient, especially derived using GFC,
effectively capture a reliable feature of the human brain
subject to interpretable and biologically meaningful
individual variation, offering some advantages over
traditional edge-wise FC measures in the search for
brain-behavior associations.},
Doi = {10.1002/hbm.26517},
Key = {fds373506}
}
@article{fds374319,
Author = {Synergy for the Influence of the Month of Birth in ADHD
(SIMBA) study group},
Title = {Association between relative age at school and persistence
of ADHD in prospective studies: an individual participant
data meta-analysis.},
Journal = {Lancet Psychiatry},
Volume = {10},
Number = {12},
Pages = {922-933},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1016/S2215-0366(23)00272-9},
Abstract = {BACKGROUND: The youngest children in a school class are more
likely than the oldest to be diagnosed with ADHD, but this
relative age effect is less frequent in older than in
younger school-grade children. However, no study has
explored the association between relative age and the
persistence of ADHD diagnosis at older ages. We aimed to
quantify the association between relative age and
persistence of ADHD at older ages. METHODS: For this
meta-analysis, we searched MEDLINE, Embase, CINAHL,
PsycINFO, and PubPsych up to April 1, 2022, with terms
related to "cohort" and "ADHD" with no date, publication
type, or language restrictions. We gathered individual
participant data from prospective cohorts that included at
least ten children identified with ADHD before age 10 years.
ADHD was defined by either a clinical diagnosis or symptoms
exceeding clinical cutoffs. Relative age was recorded as the
month of birth in relation to the school-entry cutoff date.
Study authors were invited to share raw data or to apply a
script to analyse data locally and generate anonymised
results. Our outcome was ADHD status at a diagnostic
reassessment, conducted at least 4 years after the initial
assessment and after age 10 years. No information on sex,
gender, or ethnicity was collected. We did a two-stage
random-effects individual participant data meta-analysis to
assess the association of relative age with persistence of
ADHD at follow-up. This study was registered with PROSPERO,
CRD42020212650. FINDINGS: Of 33 119 studies generated by
our search, we identified 130 eligible unique studies and
were able to gather individual participant data from 57
prospective studies following up 6504 children with ADHD.
After exclusion of 16 studies in regions with a flexible
school entry system that did not allow confident linkage of
birthdate to relative age, the primary analysis included 41
studies in 15 countries following up 4708 children for a
period of 4 to 33 years. We found that younger relative age
was not statistically significantly associated with ADHD
persistence at follow-up (odds ratio 1·02, 95% CI
0·99-1·06; p=0·19). We observed statistically significant
heterogeneity in our model (Q=75·82, p=0·0011, I2=45%).
Participant-level sensitivity analyses showed similar
results in cohorts with a robust relative age effect at
baseline and when restricting to cohorts involving children
with a clinical diagnosis of ADHD or with a follow-up
duration of more than 10 years. INTERPRETATION: The
diagnosis of ADHD in younger children in a class is no more
likely to be disconfirmed over time than that of older
children in the class. One interpretation is that the
relative age effect decreases the likelihood of children of
older relative age receiving a diagnosis of ADHD, and
another is that assigning a diagnostic label of ADHD leads
to unexplored carryover effects of the initial diagnosis
that persist over time. Future studies should be conducted
to explore these interpretations further. FUNDING:
None.},
Doi = {10.1016/S2215-0366(23)00272-9},
Key = {fds374319}
}
@article{fds371652,
Author = {Røysamb, E and Moffitt, TE and Caspi, A and Ystrøm, E and Nes,
RB},
Title = {Worldwide Well-Being: Simulated Twins Reveal Genetic and
(Hidden) Environmental Influences.},
Journal = {Perspectives on psychological science : a journal of the
Association for Psychological Science},
Volume = {18},
Number = {6},
Pages = {1562-1574},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1177/17456916231178716},
Abstract = {What are the major sources of worldwide variability in
subjective well-being (SWB)? Twin and family studies of SWB
have found substantial heritability and strong effects from
unique environments but virtually no effects from shared
environments. However, extant findings are not necessarily
valid at the global level. Prior studies have examined
within-countries variability but did not take into account
mean differences across nations. In this article, we aim to
estimate the effects of genetic factors, individual
environmental exposures, and shared environments for the
global population. We combine a set of knowns from national
well-being studies (means and standard deviations) and
behavioral-genetic studies (heritability) to model a
scenario of twin studies across 157 countries. For each
country, we simulate data for a set of twin pairs and pool
the data into a global sample. We find a worldwide
heritability of 31% to 32% for SWB. Individual environmental
factors explain 46% to 52% of the variance (including
measurement error), and shared environments account for 16%
to 23% of the global variance in SWB. Worldwide, well-being
is somewhat less heritable than within nations. In contrast
to previous within-countries studies, we find a notable
effect of shared environments. This effect is not limited to
within families but operates at a national
level.},
Doi = {10.1177/17456916231178716},
Key = {fds371652}
}
@article{fds374320,
Author = {Caspi, A and Shireby, G and Mill, J and Moffitt, TE and Sugden, K and Hannon, E},
Title = {Accelerated Pace of Aging in Schizophrenia: Five
Case-Control Studies.},
Journal = {Biological psychiatry},
Pages = {S0006-3223(23)01693-1},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1016/j.biopsych.2023.10.023},
Abstract = {<h4>Background</h4>Schizophrenia is associated with
increased risk of developing multiple aging-related
diseases, including metabolic, respiratory, and
cardiovascular diseases, and Alzheimer's and related
dementias, leading to the hypothesis that schizophrenia is
accompanied by accelerated biological aging. This has been
difficult to test because there is no widely accepted
measure of biological aging. Epigenetic clocks are promising
algorithms that are used to calculate biological age on the
basis of information from combined cytosine-phosphate-guanine
sites (CpGs) across the genome, but they have yielded
inconsistent and often negative results about the
association between schizophrenia and accelerated aging.
Here, we tested the schizophrenia-aging hypothesis using a
DNA methylation measure that is uniquely designed to predict
an individual's rate of aging.<h4>Methods</h4>We brought
together 5 case-control datasets to calculate DunedinPACE
(Pace of Aging Calculated from the Epigenome), a new measure
trained on longitudinal data to detect differences between
people in their pace of aging over time. Data were available
from 1812 psychosis cases (schizophrenia or first-episode
psychosis) and 1753 controls. Mean chronological age was
38.9 (SD = 13.6) years.<h4>Results</h4>We observed
consistent associations across datasets between
schizophrenia and accelerated aging as measured by
DunedinPACE. These associations were not attributable to
tobacco smoking or clozapine medication.<h4>Conclusions</h4>Schizophrenia
is accompanied by accelerated biological aging by midlife.
This may explain the wide-ranging risk among people with
schizophrenia for developing multiple different age-related
physical diseases, including metabolic, respiratory, and
cardiovascular diseases, and dementia. Measures of
biological aging could prove valuable for assessing
patients' risk for physical and cognitive decline and for
evaluating intervention effectiveness.},
Doi = {10.1016/j.biopsych.2023.10.023},
Key = {fds374320}
}
@article{fds372022,
Author = {Kessing, LV and Ziersen, SC and Caspi, A and Moffitt, TE and Andersen,
PK},
Title = {Lifetime Incidence of Treated Mental Health Disorders and
Psychotropic Drug Prescriptions and Associated Socioeconomic
Functioning.},
Journal = {JAMA psychiatry},
Volume = {80},
Number = {10},
Pages = {1000-1008},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1001/jamapsychiatry.2023.2206},
Abstract = {<h4>Importance</h4>Few studies have estimated the lifetime
incidence of mental health disorders and the association
with socioeconomic functioning.<h4>Objective</h4>To
investigate whether the lifetime incidence of treated mental
health disorders is substantially higher than previously
reported and estimate associations with long-term
socioeconomic difficulties.<h4>Design, setting, and
participants</h4>This nationwide population-based register
linkage study includes a randomly selected sample of 1.5
million individuals from the population of Denmark from 1995
to 2018. Data were analyzed from May 2022 to March
2023.<h4>Main outcomes and measures</h4>Lifetime incidence
of any treated mental health disorder in the general
population was estimated from birth to age 100 years taking
into account the competing risk of all-cause death and
associations with socioeconomic functioning. Register
measures were (1) from hospitals, a diagnosis of any mental
health disorder at an inpatient/outpatient hospital contact;
(2) from hospitals and prescription statistics, any mental
health disorder/psychotropic prescription, including a
hospital-contact diagnosis, or any psychotropic medication
prescribed by physicians, including general practitioners or
private psychiatrists; and (3) socioeconomic functioning as
indicated by highest educational achievement, employment,
income, residential status, and marital status.<h4>Results</h4>Among
a sample of 462 864 individuals with any mental health
disorder, the median (IQR) age was 36.6 years (21.0-53.6
years), 233 747 (50.5%) were male, and 229 117 (49.5%)
were female. Of these, 112 641 were registered with a
hospital-contact mental health disorder diagnosis and
422 080 with a prescription of psychotropic medication.
The cumulative incidence of a hospital-contact mental health
disorder diagnosis was 29.0% (95% CI, 28.8-29.1), 31.8% (95%
CI, 31.6-32.0) for females, and 26.1% (95% CI, 25.9-26.3)
for males. When also considering psychotropic prescriptions,
the cumulative incidence of any mental health
disorder/psychotropic prescription was 82.6% (95% CI,
82.4-82.6), 87.5% (95% CI, 87.4-87.7) for females, and 76.7%
(95% CI, 76.5-76.8) for males. Socioeconomic difficulties
were associated with mental health disorder/psychotropic
prescriptions, including lower income (hazard ratio [HR],
1.55; 95% CI, 1.53-1.56), increased unemployment or
disability benefit (HR, 2.50; 95% CI, 2.47-2.53), and a
greater likelihood of living alone (HR, 1.78; 95% CI,
1.76-1.80) and being unmarried (HR, 2.02; 95% CI, 2.01-2.04)
during long-term follow-up. These rates were confirmed in 4
sensitivity analyses with the lowest being 74.8% (95% CI,
74.7-75.0) (1) by using varying exclusion periods, (2) by
excluding prescriptions of anxiolytics and quetiapine that
may be used for off-label indications, (3) by defining any
mental health disorder/psychotropic prescription as any
hospital-contact mental health disorder diagnosis or any
psychotropic medication prescribed at least 2 times, and (4)
by excluding individuals with somatic diagnoses for which
psychotropics may be prescribed off-label.<h4>Conclusions
and relevance</h4>This registry study of data from a large
representative sample of the Danish population showed that
the majority of individuals either received a diagnosis of a
mental health disorder or were prescribed psychotropic
medication during their lifetime, which was associated with
subsequent socioeconomic difficulties. These findings may
help change our understanding of normalcy and mental
illness, reduce stigmatization, and further prompt
rethinking the primary prevention of mental illness and
future mental health clinical resources.},
Doi = {10.1001/jamapsychiatry.2023.2206},
Key = {fds372022}
}
@article{fds373683,
Author = {Whitman, ET and Ryan, CP and Abraham, WC and Addae, A and Corcoran, DL and Elliott, ML and Hogan, S and Ireland, D and Keenan, R and Knodt, AR and Melzer, TR and Poulton, R and Ramrakha, S and Sugden, K and Williams,
BS and Zhou, J and Hariri, AR and Belsky, DW and Moffitt, TE and Caspi,
A},
Title = {A blood biomarker of accelerated aging in the body
associates with worse structural integrity in the brain:
replication across three cohorts.},
Journal = {medRxiv},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1101/2023.09.06.23295140},
Abstract = {Biological aging is the correlated decline of multi-organ
system integrity central to the etiology of many age-related
diseases. A novel epigenetic measure of biological aging,
DunedinPACE, is associated with cognitive dysfunction,
incident dementia, and mortality. Here, we tested for
associations between DunedinPACE and structural MRI
phenotypes in three datasets spanning midlife to advanced
age: the Dunedin Study (age=45 years), the Framingham Heart
Study Offspring Cohort (mean age=63 years), and the
Alzheimer's Disease Neuroimaging Initiative (mean age=75
years). We also tested four additional epigenetic measures
of aging: the Horvath clock, the Hannum clock, PhenoAge, and
GrimAge. Across all datasets (total N observations=3,380;
total N individuals=2,322), faster DunedinPACE was
associated with lower total brain volume, lower hippocampal
volume, and thinner cortex. In two datasets, faster
DunedinPACE was associated with greater burden of white
matter hyperintensities. Across all measures, DunedinPACE
and GrimAge had the strongest and most consistent
associations with brain phenotypes. Our findings suggest
that single timepoint measures of multi-organ decline such
as DunedinPACE could be useful for gauging nervous system
health.},
Doi = {10.1101/2023.09.06.23295140},
Key = {fds373683}
}
@article{fds367501,
Author = {Slutske, WS and Richmond-Rakerd, LS and Piasecki, TM and Ramrakha, S and Poulton, R and Moffitt, TE and Caspi, A},
Title = {Disordered gambling in a longitudinal birth cohort: from
childhood precursors to adult life outcomes.},
Journal = {Psychological medicine},
Volume = {53},
Number = {12},
Pages = {5800-5808},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1017/s0033291722003051},
Abstract = {<h4>Background</h4>Despite its introduction into the
diagnostic nomenclature over four decades ago, there remain
large knowledge gaps about disordered gambling. The primary
aims of the present study were to document the long-term
course, childhood precursors, and adult life outcomes
associated with disordered gambling.<h4>Methods</h4>Participants
enrolled in the population-representative Dunedin Study were
prospectively followed from birth through age 45. Disordered
gambling was assessed six times from age 18; composite
measures of childhood social class, general intelligence,
and low self-control were based on assessments obtained from
birth through age 15; adult socioeconomic, financial, and
legal outcomes were obtained through age 45. Lifetime
disordered gambling was predicted from the three childhood
precursors and the adult outcomes were predicted from
lifetime disordered gambling.<h4>Results</h4>Past-year
disordered gambling usually occurred at only a single time
point and recurrence was relatively uncommon. Lower
childhood social class, general intelligence, and
self-control significantly predicted lifetime disordered
gambling in adulthood. In turn, lifetime disordered gambling
in adulthood significantly predicted occupational,
educational, and financial problems in adulthood (<i>ds</i>
= 0.23-0.41). These associations were markedly reduced and
sometimes rendered nonsignificant after adjusting for
childhood precursors (<i>ds</i> = 0.04-0.32).<h4>Conclusions</h4>Socioeconomic,
financial, and legal outcomes in adulthood are not merely
consequences of disordered gambling, but also are predicted
from childhood precursors. Deflecting the trajectories of
young people at risk for developing disordered gambling may
help to ameliorate not just the development of later
disordered gambling, but also other associated adverse
outcomes.},
Doi = {10.1017/s0033291722003051},
Key = {fds367501}
}
@article{fds373923,
Author = {Ruiz, B and Broadbent, JM and Thomson, WM and Ramrakha, S and Moffitt,
TE and Caspi, A and Poulton, R},
Title = {Childhood caries is associated with poor health and a faster
pace of aging by midlife.},
Journal = {Journal of public health dentistry},
Volume = {83},
Number = {4},
Pages = {381-388},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1111/jphd.12591},
Abstract = {<h4>Objectives</h4>Childhood caries is associated with
poorer self-rated general health in adulthood, but it
remains unclear whether that holds for physical health and
aging. The aim of this study was to identify whether age-5
caries is associated with (a) biomarkers for poor physical
health, and (b) the pace of aging (PoA) by age
45 years.<h4>Methods</h4>Participants are members of the
Dunedin Multidisciplinary Health and Development Study birth
cohort. At age 45, 94.1% (n = 938) of those still alive
took part. Data on age-5 caries experience and age-45 health
biomarkers were collected. The PoA captures age-related
decline across the cardiovascular, metabolic, renal, immune,
dental and pulmonary systems from age 26 to 45 years. We
used (a) generalized estimating equations to examine
associations between age-5 caries and poor physical health
by age 45 years, and (b) ordinary least squares regression
to examine whether age-5 caries was associated with the PoA.
Analyses adjusted for sex, perinatal health, childhood SES
and childhood IQ.<h4>Results</h4>High caries experience at
age-5 was associated with higher risk for some metabolic
abnormalities, including BMI ≥30, high waist
circumference, and high serum leptin. Those with high caries
experience at age-5 were aging at a faster rate by age
45 years than those who had been caries-free.<h4>Conclusions</h4>Oral
health is essential for wellbeing. Poor oral health can be
an early signal of a trajectory towards poor health in
adulthood. Management for both conditions should be
better-integrated; and integrated population-level
prevention strategies should be foundational to any health
system.},
Doi = {10.1111/jphd.12591},
Key = {fds373923}
}
@article{fds370497,
Author = {Sugden, K and Moffitt, TE and Arpawong, TE and Arseneault, L and Belsky,
DW and Corcoran, DL and Crimmins, EM and Hannon, E and Houts, R and Mill,
JS and Poulton, R and Ramrakha, S and Wertz, J and Williams, BS and Caspi,
A},
Title = {Cross-National and Cross-Generational Evidence That
Educational Attainment May Slow the Pace of Aging in
European-Descent Individuals.},
Journal = {The journals of gerontology. Series B, Psychological
sciences and social sciences},
Volume = {78},
Number = {8},
Pages = {1375-1385},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1093/geronb/gbad056},
Abstract = {<h4>Objectives</h4>Individuals with more education are at
lower risk of developing multiple, different age-related
diseases than their less-educated peers. A reason for this
might be that individuals with more education age slower.
There are 2 complications in testing this hypothesis. First,
there exists no definitive measure of biological aging.
Second, shared genetic factors contribute toward both lower
educational attainment and the development of age-related
diseases. Here, we tested whether the protective effect of
educational attainment was associated with the pace of aging
after accounting for genetic factors.<h4>Methods</h4>We
examined data from 5 studies together totaling almost 17,000
individuals with European ancestry born in different
countries during different historical periods, ranging in
age from 16 to 98 years old. To assess the pace of aging, we
used DunedinPACE, a DNA methylation algorithm that reflects
an individual's rate of aging and predicts age-related
decline and Alzheimer's disease and related disorders. To
assess genetic factors related to education, we created a
polygenic score based on the results of a genome-wide
association study of educational attainment.<h4>Results</h4>Across
the 5 studies, and across the life span, higher educational
attainment was associated with a slower pace of aging even
after accounting for genetic factors (meta-analysis effect
size = -0.20; 95% confidence interval [CI]: -0.30 to -0.10;
p = .006). Further, this effect persisted after taking into
account tobacco smoking (meta-analysis effect size = -0.13;
95% CI: -0.21 to -0.05; p = .01).<h4>Discussion</h4>These
results indicate that higher levels of education have
positive effects on the pace of aging, and that the benefits
can be realized irrespective of individuals'
genetics.},
Doi = {10.1093/geronb/gbad056},
Key = {fds370497}
}
@article{fds371651,
Author = {Wertz, J and Moffitt, TE and Arseneault, L and Barnes, JC and Boivin, M and Corcoran, DL and Danese, A and Hancox, RJ and Harrington, H and Houts,
RM and Langevin, S and Liu, H and Poulton, R and Sugden, K and Tanksley,
PT and Williams, BS and Caspi, A},
Title = {Genetic associations with parental investment from
conception to wealth inheritance in six cohorts.},
Journal = {Nature human behaviour},
Volume = {7},
Number = {8},
Pages = {1388-1401},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1038/s41562-023-01618-5},
Abstract = {Genetic inheritance is not the only way parents' genes may
affect children. It is also possible that parents' genes are
associated with investments into children's development. We
examined evidence for links between parental genetics and
parental investments, from the prenatal period through to
adulthood, using data from six population-based cohorts in
the UK, US and New Zealand, together totalling 36,566
parents. Our findings revealed associations between parental
genetics-summarized in a genome-wide polygenic score-and
parental behaviour across development, from smoking in
pregnancy, breastfeeding in infancy, parenting in childhood
and adolescence, to leaving a wealth inheritance to adult
children. Effect sizes tended to be small at any given time
point, ranging from RR = 1.12 (95% confidence interval
(95%CI) 1.09, 1.15) to RR = 0.76 (95%CI 0.72, 0.80)
during the prenatal period and infancy; β = 0.07 (95%CI
0.04, 0.11) to β = 0.29 (95%CI 0.27, 0.32) in childhood
and adolescence, and RR = 1.04 (95%CI 1.01, 1.06) to
RR = 1.11 (95%CI 1.07, 1.15) in adulthood. There was
evidence for accumulating effects across development,
ranging from β = 0.15 (95%CI 0.11, 0.18) to
β = 0.23 (95%CI 0.16, 0.29) depending on cohort. Our
findings are consistent with the interpretation that parents
pass on advantages to offspring not only via direct genetic
transmission or purely environmental paths, but also via
genetic associations with parental investment from
conception to wealth inheritance.},
Doi = {10.1038/s41562-023-01618-5},
Key = {fds371651}
}
@article{fds366660,
Author = {Bourassa, KJ and Moffitt, TE and Harrington, H and Houts, R and Poulton,
R and Ramrakha, S and Rasmussen, LJH and Wertz, J and Caspi,
A},
Title = {Childhood Adversity and Midlife Health: Shining a Light on
the Black Box of Psychosocial Mechanisms.},
Journal = {Prevention science : the official journal of the Society for
Prevention Research},
Volume = {24},
Number = {5},
Pages = {817-828},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1007/s11121-022-01431-y},
Abstract = {Adverse childhood experiences (ACEs) are associated with
poorer health, which has spurred public health efforts to
reduce the number of adverse events children experience.
Unfortunately, it is unlikely that all ACEs can be
prevented. For adults who already experienced ACEs in
childhood, what psychological, social, and behavioral
intervention targets might reduce risk for negative health
outcomes? To provide insight into the "black box" of
psychosocial mechanisms linking ACEs to poor health, our
study used data from the Dunedin Study, a longitudinal
cohort assessed from birth to age 45. Mediation models
(N = 859) were used to examine whether candidate
psychosocial variables in adulthood explained the
association between childhood ACEs and health in midlife.
Potential psychosocial mediators included stressful life
events, perceived stress, negative emotionality, and health
behaviors. Children who experienced more ACEs had poorer
health in midlife. They also had significantly more
stressful life events, more perceived stress, more negative
emotionality, and unhealthier behaviors as adults. These
mediators were each independently associated with poorer
health in midlife and statistically mediated the association
between ACEs and midlife health. Health behaviors evidenced
the strongest indirect effect from ACEs to midlife health.
Together, these psychosocial mediators accounted for the
association between ACEs in childhood and health three
decades later. Public health efforts to mitigate the health
consequences of ACEs could aim to reduce the stressful life
events people experience, reduce negative emotionality,
reduce perceived stress, or improve health behaviors among
adults who experienced childhood adversity.},
Doi = {10.1007/s11121-022-01431-y},
Key = {fds366660}
}
@article{fds369352,
Author = {Gjerde, LC and Eilertsen, EM and McAdams, TA and Cheesman, R and Moffitt, TE and Caspi, A and Eley, TC and Røysamb, E and Rosenström,
TH and Ystrom, E},
Title = {The p factor of psychopathology and personality in
middle childhood: genetic and gestational risk
factors.},
Journal = {Psychological medicine},
Volume = {53},
Number = {9},
Pages = {4275-4285},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1017/s0033291723000077},
Abstract = {<h4>Background</h4>A joint, hierarchical structure of
psychopathology and personality has been reported in adults
but should also be investigated at earlier ages, as
psychopathology often develops before adulthood. Here, we
investigate the joint factor structure of psychopathology
and personality in eight-year-old children, estimate factor
heritability and explore external validity through
associations with established developmental risk
factors.<h4>Methods</h4>Phenotypic and biometric exploratory
factor analyses with bifactor rotation on genetically
informative data from the Norwegian Mother, Father, and
Child Cohort (MoBa) study. The analytic sub-sample comprised
10 739 children (49% girls). Mothers reported their
children's symptoms of depression (Short Moods and Feelings
Questionnaire), anxiety (Screen for Anxiety Related
Disorders), attention-deficit/hyperactivity disorder
inattention and hyperactivity, oppositional-defiant
disorder, conduct disorder (Parent/Teacher Rating Scale for
Disruptive Behavior Disorders), and Big Five personality
(short Hierarchical Personality Inventory for Children).
Developmental risk factors (early gestational age and being
small for gestational age) were collected from the Medical
Birth Registry.<h4>Results</h4>Goodness-of-fit indices
favored a <i>p</i> factor model with three residual latent
factors interpreted as negative affectivity, positive
affectivity, and antagonism, whereas psychometric indices
favored a one-factor model. ADE solutions fitted best, and
regression analyses indicated a negative association between
gestational age and the <i>p</i> factor, for both the one-
and four-factor solutions.<h4>Conclusion</h4>Correlations
between normative and pathological traits in middle
childhood mostly reflect one heritable and psychometrically
interpretable <i>p</i> factor, although optimal fit to data
required less interpretable residual latent factors. The
association between the <i>p</i> factor and low gestational
age warrants further study of early developmental
mechanisms.},
Doi = {10.1017/s0033291723000077},
Key = {fds369352}
}
@article{fds370101,
Author = {Newbury, JB and Arseneault, L and Moffitt, TE and Odgers, CL and Howe,
LD and Bakolis, I and Reuben, A and Danese, A and Sugden, K and Williams,
B and Rasmussen, LJH and Trotta, A and Ambler, AP and Fisher,
HL},
Title = {Socioenvironmental Adversity and Adolescent Psychotic
Experiences: Exploring Potential Mechanisms in a UK
Longitudinal Cohort.},
Journal = {Schizophrenia bulletin},
Volume = {49},
Number = {4},
Pages = {1042-1054},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1093/schbul/sbad017},
Abstract = {<h4>Background and hypothesis</h4>Children exposed to
socioenvironmental adversities (eg, urbanicity, pollution,
neighborhood deprivation, crime, and family disadvantage)
are more likely to subsequently develop subclinical
psychotic experiences during adolescence (eg, hearing
voices, paranoia). However, the pathways through which this
occurs have not been previously investigated. We
hypothesized that cognitive ability and inflammation would
partly explain this association.<h4>Study design</h4>Data
were utilized from the Environmental-Risk Longitudinal Twin
Study, a cohort of 2232 children born in 1994-1995 in
England and Wales and followed to age 18. Socioenvironmental
adversities were measured from birth to age 10 and
classified into physical risk (defined by high urbanicity
and air pollution) and socioeconomic risk (defined by high
neighborhood deprivation, neighborhood disorder, and family
disadvantage). Cognitive abilities (overall, crystallized,
fluid, and working memory) were assessed at age 12; and
inflammatory markers (C-reactive protein, interleukin-6,
soluble urokinase plasminogen activator receptor) were
measured at age 18 from blood samples. Participants were
interviewed at age 18 regarding psychotic
experiences.<h4>Study results</h4>Higher physical risk and
socioeconomic risk were associated with increased odds of
psychotic experiences in adolescence. The largest mediation
pathways were from socioeconomic risk via overall cognitive
ability and crystallized ability, which accounted for ~11%
and ~19% of the association with psychotic experiences,
respectively. No statistically significant pathways were
found via inflammatory markers in exploratory (partially
cross-sectional) analyses.<h4>Conclusions</h4>Cognitive
ability, especially crystallized ability, may partly explain
the association between childhood socioenvironmental
adversity and adolescent psychotic experiences.
Interventions to support cognitive development among
children living in disadvantaged settings could buffer them
against developing subclinical psychotic
phenomena.},
Doi = {10.1093/schbul/sbad017},
Key = {fds370101}
}
@article{fds370499,
Author = {Gjerde, LC and Eilertsen, EM and McAdams, TA and Cheesman, R and Moffitt, TE and Caspi, A and Eley, TC and Røysamb, E and Rosenström,
TH and Ystrom, E},
Title = {The p factor of psychopathology and personality in
middle childhood: Genetic and gestational risk factors -
Corrigendum.},
Journal = {Psychological medicine},
Volume = {53},
Number = {9},
Pages = {4303-4304},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1017/s0033291723000879},
Doi = {10.1017/s0033291723000879},
Key = {fds370499}
}
@article{fds373684,
Author = {Tanksley, PT and Brislin, SJ and Wertz, J and de Vlaming, R and Courchesne-Krak, NS and Mallard, TT and Raffington, LL and Linnér,
RK and Koellinger, P and Palmer, A and Sanchez-Roige, A and Waldman, I and Dick, D and Moffitt, TE and Caspi, A and Harden, KP},
Title = {Do polygenic indices capture "direct" effects on child
externalizing behavior? Within-family analyses in two
longitudinal birth cohorts.},
Journal = {medRxiv},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1101/2023.05.31.23290802},
Abstract = {Behaviors and disorders characterized by difficulties with
self-regulation, such as problematic substance use,
antisocial behavior, and symptoms of attention-deficit/hyperactivity
disorder (ADHD), incur high costs for individuals, families,
and communities. These externalizing behaviors often appear
early in the life course and can have far-reaching
consequences. Researchers have long been interested in
direct measurements of genetic risk for externalizing
behaviors, which can be incorporated alongside other known
risk factors to improve efforts at early identification and
intervention. In a preregistered analysis drawing on data
from the Environmental Risk (E-Risk) Longitudinal Twin Study
(N=862 twins) and the Millennium Cohort Study (MCS; N=2,824
parent-child trios), two longitudinal cohorts from the UK,
we leveraged molecular genetic data and within-family
designs to test for genetic effects on externalizing
behavior that are unbiased by the common sources of
environmental confounding. Results are consistent with the
conclusion that an externalizing polygenic index (PGI)
captures causal effects of genetic variants on externalizing
problems in children and adolescents, with an effect size
that is comparable to those observed for other established
risk factors in the research literature on externalizing
behavior. Additionally, we find that polygenic associations
vary across development (peaking from age 5-10 years), that
parental genetics (assortment and parent-specific effects)
and family-level covariates affect prediction little, and
that sex differences in polygenic prediction are present but
only detectable using within-family comparisons. Based on
these findings, we believe that the PGI for externalizing
behavior is a promising means for studying the development
of disruptive behaviors across child development.},
Doi = {10.1101/2023.05.31.23290802},
Key = {fds373684}
}
@article{fds370496,
Author = {Bourassa, KJ and Caspi, A and Brennan, GM and Hall, KS and Harrington,
H and Houts, R and Kimbrel, NA and Poulton, R and Ramrakha, S and Taylor,
GA and Moffitt, TE},
Title = {Which Types of Stress Are Associated With Accelerated
Biological Aging? Comparing Perceived Stress, Stressful Life
Events, Childhood Adversity, and Posttraumatic Stress
Disorder.},
Journal = {Psychosom Med},
Volume = {85},
Number = {5},
Pages = {389-396},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1097/PSY.0000000000001197},
Abstract = {OBJECTIVE: Stress and stressful events are associated with
poorer health; however, there are multiple ways to
conceptualize and measure stress and stress responses. One
physiological mechanism through which stress could result in
poorer health is accelerated biological aging. This study
tested which types of stress were associated with
accelerated biological aging in adulthood. METHODS: Studying
955 participants from the Dunedin Longitudinal Study, we
tested whether four types of stress assessed from ages 32 to
45 years-perceived stress, number of stressful life events,
adverse childhood experiences, and posttraumatic stress
disorder-were associated with accelerated biological aging.
RESULTS: Higher levels of all four measures of stress were
significantly associated with accelerated aging in separate
models. In a combined model, more perceived stress and more
stressful life events remained associated with faster aging,
and the stress measures explained 6.9% of the variance in
aging. The magnitudes of the associations between the four
measures of stress and biological aging were comparable to
associations for smoking and low education, two established
risk factors for accelerated aging. People with high levels
of perceived stress, numerous adverse childhood experiences
(4+), high stressful life event counts, or posttraumatic
stress disorder were aging an additional estimated 2.4
months, 1.1 additional months, 1.4 months, and 1.4 months
per year, respectively. CONCLUSIONS: Assessing stress,
particularly perceived stress, could help identify people at
risk of accelerated aging. Intervening to treat stress or
the health-relevant sequelae of stress could potentially
slow the rate at which people are aging, improving their
health as they age.},
Doi = {10.1097/PSY.0000000000001197},
Key = {fds370496}
}
@article{fds370498,
Author = {Whitman, ET and Knodt, AR and Elliott, ML and Abraham, WC and Cheyne, K and Hogan, S and Ireland, D and Keenan, R and Leung, JH and Melzer, TR and Poulton, R and Purdy, SC and Ramrakha, S and Thorne, PR and Caspi, A and Moffitt, TE and Hariri, AR},
Title = {Functional topography of the neocortex predicts covariation
in complex cognitive and basic motor abilities.},
Journal = {Cerebral cortex (New York, N.Y. : 1991)},
Volume = {33},
Number = {13},
Pages = {8218-8231},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1093/cercor/bhad109},
Abstract = {Although higher-order cognitive and lower-order sensorimotor
abilities are generally regarded as distinct and studied
separately, there is evidence that they not only covary but
also that this covariation increases across the lifespan.
This pattern has been leveraged in clinical settings where a
simple assessment of sensory or motor ability (e.g. hearing,
gait speed) can forecast age-related cognitive decline and
risk for dementia. However, the brain mechanisms underlying
cognitive, sensory, and motor covariation are largely
unknown. Here, we examined whether such covariation in
midlife reflects variability in common versus distinct
neocortical networks using individualized maps of functional
topography derived from BOLD fMRI data collected in 769
45-year-old members of a population-representative cohort.
Analyses revealed that variability in basic motor but not
hearing ability reflected individual differences in the
functional topography of neocortical networks typically
supporting cognitive ability. These patterns suggest that
covariation in motor and cognitive abilities in midlife
reflects convergence of function in higher-order neocortical
networks and that gait speed may not be simply a measure of
physical function but rather an integrative index of nervous
system health.},
Doi = {10.1093/cercor/bhad109},
Key = {fds370498}
}
@article{fds370500,
Author = {Madrid-Valero, JJ and Matthews, T and Barclay, NL and Odgers, CL and Moffitt, TE and Caspi, A and Arseneault, L and Gregory,
AM},
Title = {Problematic technology use and sleep quality in young
adulthood: novel insights from a nationally representative
twin study.},
Journal = {Sleep},
Volume = {46},
Number = {6},
Pages = {zsad038},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1093/sleep/zsad038},
Abstract = {<h4>Study objectives</h4>Digital technology use is
associated with poor sleep quality in adolescence and young
adulthood although research findings have been mixed. No
studies have addressed the association between the two using
a genetically informative twin design which could extend our
understanding of the etiology of this relationship. This
study aimed to test: (1) the association between
adolescents' perceived problematic use of digital technology
and poor sleep quality, (2) whether the association between
problematic use of technology and poor sleep quality remains
after controlling for familial factors, and (3) genetic and
environmental influences on the association between
problematic use of technology and poor sleep
quality.<h4>Methods</h4>Participants were 2232 study members
(18-year-old twins) of the Environmental Risk (E-Risk)
Longitudinal Twin Study. The sample was 48.9% male, 90%
white, and 55.6% monozygotic. We conducted regression and
twin difference analyses and fitted twin
models.<h4>Results</h4>Twin differences for problematic use
of technology were associated with differences for poor
sleep quality in the whole sample (p < 0.001; B = 0.15) and
also when we limited the analyses to identical twins only (p
< 0.001; B = 0.21). We observed a substantial genetic
correlation between problematic use of technology and sleep
quality (rA = 0.31), whereas the environmental correlation
was lower (rE = 0.16).<h4>Conclusions</h4>Adolescent
reported problematic use of digital technology is associated
with poor sleep quality-even after controlling for familial
factors including genetic confounds. Our results suggest
that the association between adolescents' sleep and
problematic digital technology use is not accounted for by
shared genetic liability or familial factors but could
reflect a causal association. This robust association needs
to be examined in future research designed to test causal
associations.},
Doi = {10.1093/sleep/zsad038},
Key = {fds370500}
}
@article{fds362161,
Author = {Matthews, T and Qualter, P and Bryan, BT and Caspi, A and Danese, A and Moffitt, TE and Odgers, CL and Strange, L and Arseneault,
L},
Title = {The developmental course of loneliness in adolescence:
Implications for mental health, educational attainment, and
psychosocial functioning.},
Journal = {Development and psychopathology},
Volume = {35},
Number = {2},
Pages = {537-546},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1017/s0954579421001632},
Abstract = {The present study examined patterns of stability and change
in loneliness across adolescence. Data were drawn from the
Environmental Risk (E-Risk) Longitudinal Twin Study, a UK
population-representative cohort of 2,232 individuals born
in 1994 and 1995. Loneliness was assessed when participants
were aged 12 and 18. Loneliness showed modest stability
across these ages (<i>r</i> = .25). Behavioral genetic
modeling indicated that stability in loneliness was
explained largely by genetic influences (66%), while change
was explained by nonshared environmental effects (58%).
Individuals who reported loneliness at both ages were
broadly similar to individuals who only reported it at age
18, with both groups at elevated risk of mental health
problems, physical health risk behaviors, and education and
employment difficulties. Individuals who were lonely only at
age 12 generally fared better; however, they were still more
likely to finish school with lower qualifications. Positive
family influences in childhood predicted reduced risk of
loneliness at age 12, while negative peer experiences
increased the risk. Together, the findings show that while
early adolescent loneliness does not appear to exert a
cumulative burden when it persists, it is nonetheless a risk
for a range of concomitant impairments, some of which can
endure.},
Doi = {10.1017/s0954579421001632},
Key = {fds362161}
}
@article{fds370046,
Author = {Poulton, R and Caspi, A and Moffitt, TE},
Title = {Fear and anxiety: Lessons learned from the Dunedin
longitudinal study.},
Journal = {Neuroscience and biobehavioral reviews},
Volume = {148},
Pages = {105118},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1016/j.neubiorev.2023.105118},
Abstract = {Four related lines of research on anxiety were reviewed from
the 'Dunedin Study', an investigation of a representative
longitudinal birth cohort of 50-years duration, with 94%
retention at the last follow-up. Findings include: (i)
Childhood fears deemed evolutionarily-relevant may have
different pathways and/or mechanisms underlying their
emergence when compared to evolutionarilyneutral fears. (ii)
Sequential comorbidity both inside and external to the
family of disorders is the rule not the exception,
highlighting the importance of developmental history. (iii)
The developmental relationship between GAD and MDE is more
symmetric that previously assumed, with equal numbers of
persons having GAD preceding MDE and MDE preceding GAD. (iv)
PTSD in adulthood is influenced by a broad range of
childhood risk factors, sequential comorbidity is near
universal, and both high-stress life events and
mental-disorder history influence the development of PTSD.
The implications for epidemiology, nosology, the importance
of developmental history, and prevention/treatment options
are considered.},
Doi = {10.1016/j.neubiorev.2023.105118},
Key = {fds370046}
}
@article{fds370882,
Author = {Doherty, T and Dempster, E and Hannon, E and Mill, J and Poulton, R and Corcoran, D and Sugden, K and Williams, B and Caspi, A and Moffitt, TE and Delany, SJ and Murphy, TM},
Title = {A comparison of feature selection methodologies and learning
algorithms in the development of a DNA methylation-based
telomere length estimator.},
Journal = {BMC bioinformatics},
Volume = {24},
Number = {1},
Pages = {178},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1186/s12859-023-05282-4},
Abstract = {<h4>Background</h4>The field of epigenomics holds great
promise in understanding and treating disease with advances
in machine learning (ML) and artificial intelligence being
vitally important in this pursuit. Increasingly, research
now utilises DNA methylation measures at cytosine-guanine
dinucleotides (CpG) to detect disease and estimate
biological traits such as aging. Given the challenge of high
dimensionality of DNA methylation data, feature-selection
techniques are commonly employed to reduce dimensionality
and identify the most important subset of features. In this
study, our aim was to test and compare a range of
feature-selection methods and ML algorithms in the
development of a novel DNA methylation-based telomere length
(TL) estimator. We utilised both nested cross-validation and
two independent test sets for the comparisons.<h4>Results</h4>We
found that principal component analysis in advance of
elastic net regression led to the overall best performing
estimator when evaluated using a nested cross-validation
analysis and two independent test cohorts. This approach
achieved a correlation between estimated and actual TL of
0.295 (83.4% CI [0.201, 0.384]) on the EXTEND test data set.
Contrastingly, the baseline model of elastic net regression
with no prior feature reduction stage performed less well in
general-suggesting a prior feature-selection stage may have
important utility. A previously developed TL estimator,
DNAmTL, achieved a correlation of 0.216 (83.4% CI [0.118,
0.310]) on the EXTEND data. Additionally, we observed that
different DNA methylation-based TL estimators, which have
few common CpGs, are associated with many of the same
biological entities.<h4>Conclusions</h4>The variance in
performance across tested approaches shows that estimators
are sensitive to data set heterogeneity and the development
of an optimal DNA methylation-based estimator should benefit
from the robust methodological approach used in this study.
Moreover, our methodology which utilises a range of
feature-selection approaches and ML algorithms could be
applied to other biological markers and disease phenotypes,
to examine their relationship with DNA methylation and
predictive value.},
Doi = {10.1186/s12859-023-05282-4},
Key = {fds370882}
}
@article{fds368070,
Author = {Lay-Yee, R and Matthews, T and Moffitt, T and Poulton, R and Caspi, A and Milne, B},
Title = {Are trajectories of social isolation from childhood to
mid-adulthood associated with adult depression or suicide
outcomes.},
Journal = {Social psychiatry and psychiatric epidemiology},
Volume = {58},
Number = {3},
Pages = {373-382},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1007/s00127-022-02389-6},
Abstract = {<h4>Purpose</h4>Social isolation has been shown to have
negative effects on mental health outcomes though little is
known about trajectories across the life course. We examined
the relationship between trajectory groups and selected
mental health outcomes in mid-adulthood.<h4>Methods</h4>We
previously created a typology of social isolation based on
onset during the life course and persistence into adulthood,
using group-based trajectory analysis of longitudinal data
from a New Zealand birth cohort. The typology comprises four
groups: 'never-isolated', 'adult-only', 'child-only', and
'persistent (child-adult) isolation'. We undertook logistic
regression analyses of three mental health outcomes with
trajectory group as the predictor, adjusting for sex and a
range of familial and child-behavioural factors.<h4>Results</h4>Lifetime
suicide attempt, and depression and suicide ideation in
mid-adulthood were each associated with adult-only but not
child-only social isolation. Depression in mid-adulthood was
also associated with persistent child-adult social
isolation.<h4>Conclusion</h4>Although our findings are
associational and not causal, they indicate that
interrupting persistent social isolation may help to prevent
adult depression whereas halting adult social isolation may
ameliorate both depression and suicide outcomes.},
Doi = {10.1007/s00127-022-02389-6},
Key = {fds368070}
}
@article{fds370501,
Author = {Whitman, ET and Knodt, AR and Elliott, ML and Abraham, WC and Cheyne, K and Hogan, S and Ireland, D and Keenan, R and Lueng, JH and Melzer, TR and Poulton, R and Purdy, SC and Ramrakha, S and Thorne, PR and Caspi, A and Moffitt, TE and Hariri, AR},
Title = {Functional Topography of the Neocortex Predicts Covariation
in Complex Cognitive and Basic Motor Abilities.},
Journal = {bioRxiv},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1101/2023.01.09.523297},
Abstract = {Although higher-order cognitive and lower-order sensorimotor
abilities are generally regarded as distinct and studied
separately, there is evidence that they not only covary but
also that this covariation increases across the lifespan.
This pattern has been leveraged in clinical settings where a
simple assessment of sensory or motor ability (e.g.,
hearing, gait speed) can forecast age-related cognitive
decline and risk for dementia. However, the brain mechanisms
underlying cognitive, sensory, and motor covariation are
largely unknown. Here, we examined whether such covariation
in midlife reflects variability in common versus distinct
neocortical networks using individualized maps of functional
topography derived from BOLD fMRI data collected in 769
45-year old members of a population-representative cohort.
Analyses revealed that variability in basic motor but not
hearing ability reflected individual differences in the
functional topography of neocortical networks typically
supporting cognitive ability. These patterns suggest that
covariation in motor and cognitive abilities in midlife
reflects convergence of function in higher-order neocortical
networks and that gait speed may not be simply a measure of
physical function but rather an integrative index of nervous
system health.},
Doi = {10.1101/2023.01.09.523297},
Key = {fds370501}
}
@article{fds361148,
Author = {Wilson, GA and Cheyne, K and Ramrakha, S and Ambler, A and Tan, GS and Caspi, A and Williams, B and Sugden, K and Houts, R and Niederer, RL and Wong, TY and Moffitt, TE and Poulton, R},
Title = {Are macular drusen in midlife a marker of accelerated
biological ageing?},
Journal = {Clinical & experimental optometry},
Volume = {106},
Number = {1},
Pages = {41-46},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/08164622.2021.2012428},
Abstract = {<h4>Clinical relevance</h4>Macular drusen are associated
with age-related maculopathy but are not an ocular
manifestation or biomarker of systemic ageing.<h4>Background</h4>Macular
drusen are the first sign of age-related maculopathy, an eye
disease for which age is the strongest risk factor. The aim
of this cohort study was to investigate whether macular
drusen in midlife - a sign of the earliest stages of
age-related macular degeneration (AMD) - are associated with
accelerated biological ageing more generally.<h4>Methods</h4>Members
of the long-running Dunedin Multidisciplinary Health and
Development Study (hereafter the Dunedin Study, n = 1037)
underwent retinal photography at their most recent
assessment at the age of 45 years. Images were graded for
the presence of AMD using a simplified scale from the
Age-Related Eye Disease Study (AREDS). Accelerated ageing
was assessed by (i) a measure of Pace of Ageing defined from
a combination of clinical and serum biomarkers obtained at
ages 26, 32, 38, and 45 years and (ii) Facial Ageing,
defined from photographs obtained at age 38 and
45 years.<h4>Results</h4>Of the 938 participants who
participated at the age 45 assessments, 834 had gradable
retinal photographs, and of these 165 (19.8%) had macular
drusen. There was no significant difference in Pace of
Ageing (<i>p</i> = .743) or Facial Ageing (<i>p</i>
= .945) among participants with and without macular
drusen.<h4>Conclusions</h4>In this representative general
population sample, macular drusen in midlife were not
associated with accelerated ageing. Future studies tracking
longitudinal changes in drusen number and severity at older
ages may reveal whether drusen are a biomarker of
accelerated ageing.},
Doi = {10.1080/08164622.2021.2012428},
Key = {fds361148}
}
@article{fds366197,
Author = {Poulton, R and Guiney, H and Ramrakha, S and Moffitt,
TE},
Title = {The Dunedin study after half a century: reflections on the
past, and course for the future},
Journal = {Journal of the Royal Society of New Zealand},
Volume = {53},
Number = {4},
Pages = {446-465},
Publisher = {Informa UK Limited},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/03036758.2022.2114508},
Abstract = {Over the last 50 years Dunedin Study researchers have
published more than 1400 peer-reviewed journal articles,
books, and reports on many aspects of human health and
development. In this 50th anniversary piece we reflect on
(i) our historical roots and necessary re-invention through
time; (ii) the underpinning principles that have contributed
to our success; (iii) some selected examples of high-impact
work from the behavioural, oral health, and respiratory
domains; (iv) some of the challenges we have encountered
over time and how to overcome these; and (vi) review where
we see the Study going in the future. We aim to present some
of the ‘back story’, which is typically undocumented and
oft lost to memory, and thus focus on ‘know-how’. Our
hope is to humanise our research, share insights, and to
acknowledge the real heroes of the Study–the 1037 Study
members, their families and their friends, who have
collectively given so much, for so long, in the hope of
helping others.},
Doi = {10.1080/03036758.2022.2114508},
Key = {fds366197}
}
@article{fds367973,
Author = {Lorenzo, EC and Kuchel, GA and Kuo, C-L and Moffitt, TE and Diniz,
BS},
Title = {Major depression and the biological hallmarks of
aging.},
Journal = {Ageing research reviews},
Volume = {83},
Pages = {101805},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1016/j.arr.2022.101805},
Abstract = {Major depressive disorder (MDD) is characterized by
psychological and physiological manifestations contributing
to the disease severity and outcome. In recent years,
several lines of evidence have suggested that individuals
with MDD have an elevated risk of age-related adverse
outcomes across the lifespan. This review provided evidence
of a significant overlap between the biological
abnormalities in MDD and biological changes commonly
observed during the aging process (i.e., hallmarks of
biological aging). Based on such evidence, we formulate a
mechanistic model showing how abnormalities in the hallmarks
of biological aging can be a common denominator and mediate
the elevated risk of age-related health outcomes commonly
observed in MDD. Finally, we proposed a roadmap for novel
studies to investigate the intersection between the biology
of aging and MDD, including the use of geroscience-guided
interventions, such as senolytics, to delay or improve major
depression by targeting biological aging.},
Doi = {10.1016/j.arr.2022.101805},
Key = {fds367973}
}
@article{fds368322,
Author = {Guiney, H and Walker, R and Broadbent, J and Caspi, A and Goodin, E and Kokaua, J and Moffitt, TE and Robertson, S and Theodore, R and Poulton,
R and Endre, Z},
Title = {Kidney-Function Trajectories From Young Adulthood to
Midlife: Identifying Risk Strata and Opportunities for
Intervention.},
Journal = {Kidney international reports},
Volume = {8},
Number = {1},
Pages = {51-63},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1016/j.ekir.2022.10.005},
Abstract = {<h4>Introduction</h4>Understanding normative patterns of
change in kidney function over the life course may allow
targeting of early interventions to slow or prevent the
onset of kidney disease, but knowledge about kidney
functional change before middle age is limited. This study
used prospective longitudinal data from a representative
birth cohort to examine common patterns of change from young
to midadulthood and to identify risk factors and outcomes
associated with poorer trajectories.<h4>Methods</h4>We used
group-based trajectory modeling in the Dunedin study birth
cohort (<i>n</i> = 857) to identify the following: (i)
common kidney function trajectories between the ages 32 and
45 years, (ii) early-life factors associated with those
trajectories, (iii) modifiable physical and psychosocial
factors across adulthood associated with differences in
trajectory slope, and (iv) links between trajectories and
kidney-related outcomes at age 45 years.<h4>Results</h4>Three
trajectory groups were identified and could be
differentiated by age 32 years as follows: normal (58% of
participants), low-normal (36%), and high-risk (6%) groups.
Those from low socioeconomic backgrounds had higher odds of
following a high-risk (vs. normal) trajectory. Modifiable
factors (blood pressure, body mass index, inflammation,
glycated hemoglobin, smoking, and socioeconomic status)
across adulthood were associated with steeper age-related
declines in kidney function, particularly among those in the
low-normal and high-risk groups. Those in the low-normal and
high-risk groups also had more adverse kidney-related
outcomes at age 45 years.<h4>Conclusion</h4>The current
findings could be used to inform the development of early
interventions and point to socioeconomic conditions across
the life course and health-related risk factors and
behaviors in adulthood as kidney health promotion
targets.},
Doi = {10.1016/j.ekir.2022.10.005},
Key = {fds368322}
}
@article{fds370047,
Author = {Barrett-Young, A and Abraham, WC and Cheung, CY and Gale, J and Hogan,
S and Ireland, D and Keenan, R and Knodt, AR and Melzer, TR and Moffitt,
TE and Ramrakha, S and Tham, YC and Wilson, GA and Wong, TY and Hariri, AR and Poulton, R},
Title = {Associations Between Thinner Retinal Neuronal Layers and
Suboptimal Brain Structural Integrity in a Middle-Aged
Cohort.},
Journal = {Eye and brain},
Volume = {15},
Pages = {25-35},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.2147/eb.s402510},
Abstract = {<h4>Purpose</h4>The retina has potential as a biomarker of
brain health and Alzheimer's disease (AD) because it is the
only part of the central nervous system which can be easily
imaged and has advantages over brain imaging technologies.
Few studies have compared retinal and brain measurements in
a middle-aged sample. The objective of our study was to
investigate whether retinal neuronal measurements were
associated with structural brain measurements in a
middle-aged population-based cohort.<h4>Participants and
methods</h4>Participants were members of the Dunedin
Multidisciplinary Health and Development Study (n=1037; a
longitudinal cohort followed from birth and at ages 3, 5, 7,
9, 11, 13, 15, 18, 21, 26, 32, 38, and most recently at age
45, when 94% of the living Study members participated).
Retinal nerve fibre layer (RNFL) and ganglion cell-inner
plexiform layer (GC-IPL) thickness were measured by optical
coherence tomography (OCT). Brain age gap estimate
(brainAGE), cortical surface area, cortical thickness,
subcortical grey matter volumes, white matter
hyperintensities, were measured by magnetic resonance
imaging (MRI).<h4>Results</h4>Participants with both MRI and
OCT data were included in the analysis (RNFL n=828, female
n=413 [49.9%], male n=415 [50.1%]; GC-IPL n=825, female
n=413 [50.1%], male n=412 [49.9%]). Thinner retinal neuronal
layers were associated with older brain age, smaller
cortical surface area, thinner average cortex, smaller
subcortical grey matter volumes, and increased volume of
white matter hyperintensities.<h4>Conclusion</h4>These
findings provide evidence that the retinal neuronal layers
reflect differences in midlife structural brain integrity
consistent with increased risk for later AD, supporting the
proposition that the retina may be an early biomarker of
brain health.},
Doi = {10.2147/eb.s402510},
Key = {fds370047}
}
@article{fds370957,
Author = {Thomas, A and Ryan, C and Caspi, A and Moffitt, T and Sugden, K and Zhou,
J and Belsky, D and Gu, Y},
Title = {Diet, pace of biological aging, and risk of dementia in the
Framingham Heart Study},
Booktitle = {medRxiv},
Year = {2023},
url = {http://dx.doi.org/10.1101/2023.05.24.23290474},
Abstract = {<h4>Objective</h4>People who eat healthier diets are less
likely to develop dementia, but the biological mechanism of
this protection is not well understood. We tested the
hypothesis that healthy diet protects against dementia
because it slows the pace of biological aging.<h4>Methods</h4>We
analyzed Framingham Offspring Cohort data. We included
participants ≥60 years-old, free of dementia and having
dietary, epigenetic, and follow-up data. We assessed healthy
diet as long-term adherence to the Mediterranean-Dash
Intervention for Neurodegenerative Delay diet (MIND, over 4
visits spanning 1991-2008). We measured the pace of aging
from blood DNA methylation data collected in 2005-2008 using
the DunedinPACE epigenetic clock. Incident dementia and
mortality were defined using study records compiled from
2005 to 2008 visit through 2018.<h4>Results</h4>Of
n = 1,644 included participants (mean age 69.6, 54%
female), n = 140 developed dementia and n = 471 died
over 14 years of follow-up. Greater MIND score was
associated with slower DunedinPACE and reduced risks for
dementia and mortality. Slower DunedinPACE was associated
with reduced risks for dementia and mortality. In mediation
analysis, slower DunedinPACE accounted for 27% of the
diet-dementia association and 57% of the diet-mortality
association.<h4>Interpretation</h4>Findings suggest that
slower pace of aging mediates part of the relationship of
healthy diet with reduced dementia risk. Monitoring pace of
aging may inform dementia prevention. However, a large
fraction of the diet-dementia association remains
unexplained and may reflect direct connections between diet
and brain aging that do not overlap other organ systems.
Investigation of brain-specific mechanisms in well-designed
mediation studies is warranted. ANN NEUROL
2024.},
Doi = {10.1101/2023.05.24.23290474},
Key = {fds370957}
}
%% Newpher, Thomas M.
@article{fds370752,
Author = {Azizi, Y and Hession, J and Newpher, T},
Title = {Comparing Student Performance in Emergency Remote and
Face-to-Face Collaborative Learning Courses},
Journal = {Journal of Undergraduate Neuroscience Education},
Volume = {22},
Number = {2},
Pages = {A117-A125},
Publisher = {Faculty for Undergraduate Neuroscience},
Year = {2023},
Month = {May},
Key = {fds370752}
}
%% Nicolelis, Miguel A.
@article{7951637,
Author = {Wiest, M.C. and Nicolelis, M.A.L.},
Title = {Behavioral detection of tactile stimuli during 7-12 Hz
cortical oscillations in awake rats},
Journal = {Nat. Neurosci. (USA)},
Volume = {6},
Number = {9},
Pages = {913 - 14},
url = {http://dx.doi.org/10.1038/nn1107},
Keywords = {bioelectric potentials;biological techniques;brain;microelectrodes;neurophysiology;touch
(physiological);},
Abstract = {Prominent 7-12 Hz oscillations in the primary somatosensory
cortex (S1) of awake but immobile rats might represent a
seizure-like state1 in which neuronal burst firing renders
animals unresponsive to incoming tactile stimuli; others
have proposed that these oscillations are analogous to human
μ rhythm. To test whether rats can respond to tactile
stimuli during 7-12 Hz oscillatory activity, we trained
head-immobilized awake animals to indicate whether they
could detect the occurrence of transient whisker deflections
while we recorded local field potentials (LFPs) from
microelectrode arrays implanted bilaterally in the S1
whisker representation area. They responded rapidly and
reliably, suggesting that this brain rhythm represents
normal physiological activity that does not preclude
perception},
Key = {7951637}
}
%% Nowicki, Stephen
@article{fds373348,
Author = {Caves, EM and Davis, AL and Nowicki, S and Johnsen,
S},
Title = {Backgrounds and the evolution of visual signals.},
Journal = {Trends in ecology & evolution},
Volume = {39},
Number = {2},
Pages = {188-198},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1016/j.tree.2023.09.006},
Abstract = {Color signals which mediate behavioral interactions across
taxa and contexts are often thought of as color 'patches' -
parts of an animal that appear colorful compared to other
parts of that animal. Color patches, however, cannot be
considered in isolation because how a color is perceived
depends on its visual background. This is of special
relevance to the function and evolution of signals because
backgrounds give rise to a fundamental tradeoff between
color signal detectability and discriminability: as its
contrast with the background increases, a color patch
becomes more detectable, but discriminating variation in
that color becomes more difficult. Thus, the signal function
of color patches can only be fully understood by considering
patch and background together as an integrated
whole.},
Doi = {10.1016/j.tree.2023.09.006},
Key = {fds373348}
}
@article{fds374695,
Author = {Searcy, WA and Nowicki, S},
Title = {Human-wild bird cooperation.},
Journal = {Science (New York, N.Y.)},
Volume = {382},
Number = {6675},
Pages = {1124-1125},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1126/science.adl5923},
Abstract = {Honeyguides learn distinct signals made by honey hunters
from different cultures.},
Doi = {10.1126/science.adl5923},
Key = {fds374695}
}
@article{fds369125,
Author = {Searcy, WA and Chronister, LM and Nowicki, S},
Title = {Syntactic rules predict song type matching in a
songbird},
Journal = {Behavioral Ecology and Sociobiology},
Volume = {77},
Number = {1},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1007/s00265-022-03286-3},
Abstract = {Abstract: Song type matching has been hypothesized to be a
graded signal of aggression; however, it is often the case
that variation in matching behavior is unrelated to
variation in aggressiveness. An alternative view is that
whether an individual matches a song is determined mainly by
syntactic rules governing how songs are sequenced. In song
sparrows (Melospiza melodia), two such rules are the cycling
rule, which directs that a bird cycles through its song
types in close to the minimum number of bouts, and the bout
length rule, which directs that a long bout of a song type
is followed by a long interval before that song type is sung
again. The effect of these rules on matching is confirmed
here for a population of eastern song sparrows. Territorial
males were challenged at the end of a recording session with
playback of one of their own song types. Logistic regression
showed that the probability of matching the playback song
type increased with the length of the interval since the
subject had last sung that song type, as predicted by the
cycling rule. The probability of matching decreased as prior
bout length increased, as predicted by the bout length rule.
In a multivariate logistic regression, interval length and
prior bout length were both associated with matching and
together correctly predicted matching in 81.3% of cases. The
results support the syntactic constraints hypothesis, which
proposes that matching is a non-signaling by-product of
internal rules governing the ordering of song type
sequences. Significance statement: Vocal matching has
attracted widespread interest in large part because it seems
an effective method of directing an aggressive message at a
particular recipient. Here, we show that in an eastern
population of song sparrows, decisions on whether to match
another bird are largely determined by internal rules of
syntax governing how a singer sequences its song types,
rather than by variation in aggressiveness or other
individual traits. These results support the view that vocal
matching is an incidental byproduct of internal mechanisms
controlling the ordering of vocalization types and so is not
a signal at all. This hypothesis may be broadly applicable
to vocal matching in other species.},
Doi = {10.1007/s00265-022-03286-3},
Key = {fds369125}
}
%% Puffer, Eve S.
@article{fds376853,
Author = {Rasmussen, JM and Johnson, SL and Ochieng, Y and Jaguga, F and Green, E and Puffer, E},
Title = {Congregation leader and member discussions in a church-based
family strengthening, mental health promotion, and HIV
prevention trial: Intervention},
Journal = {Cambridge Prisms: Global Mental Health},
Pages = {1-36},
Publisher = {Cambridge University Press (CUP)},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1017/gmh.2024.44},
Doi = {10.1017/gmh.2024.44},
Key = {fds376853}
}
@article{fds371466,
Author = {Johnson, SL and Rasmussen, JM and Mansoor, M and Ibrahim, H and Rono, W and Goel, P and Vissoci, JRN and Von Isenburg and M and Puffer,
ES},
Title = {Correlates of Intimate Partner Violence Victimization and
Perpetration in Adolescents and Young Adults in Sub-Saharan
Africa: A Systematic Review.},
Journal = {Trauma, violence & abuse},
Volume = {25},
Number = {2},
Pages = {1168-1183},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1177/15248380231173428},
Abstract = {Intimate partner violence (IPV) is a global public health
crisis with long-term adverse consequences for both victims
and perpetrators. Patterns of violence often begin during
adolescence, yet most interventions target adult
relationships. A systematic review was conducted to identify
correlates of IPV victimization and perpetration among
adolescents and young adults in sub-Saharan Africa (SSA).
Eligible studies included participants 10 to 24 years old,
took place in SSA, and tested a statistical association
between a correlate and an IPV outcome. Correlates were
defined as any condition or characteristic associated with
statistically significant increased or decreased risk of IPV
victimization or perpetration. PsycInfo, PubMed, Embase, and
African Index Medicus were searched and included studies
published between January 1, 2000 and February 4, 2022. The
search resulted in 3,384 original studies, of which 55 met
inclusion criteria and were analyzed. Correlates were first
qualitatively synthesized by developmental period (e.g.,
early adolescence, older adolescence, and young adulthood)
and then organized in a conceptual framework by correlate
type (e.g., socio-demographic; health, behavior, and
attitudes; relational; or contextual). Over two decades of
literature reveals variability in evidence by developmental
period but also substantial overlap in the correlates of
victimization and perpetration. This review identifies
multiple points for intervention and results suggest the
urgent need for earlier, developmentally appropriate
prevention efforts among younger adolescents as well as
combined approaches that target both victimization and
perpetration of IPV.},
Doi = {10.1177/15248380231173428},
Key = {fds371466}
}
@article{fds376689,
Author = {Johnson, SL and Rieder, AD and Rasmussen, JM and Mansoor, M and Quick,
KN and Proeschold-Bell, RJ and Coping Together Team, and Boone, WJ and Puffer, ES},
Title = {A Pilot Study of the Coping Together Virtual Family
Intervention: Exploring Changes in Family Functioning and
Individual Well-Being.},
Journal = {Research on child and adolescent psychopathology},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1007/s10802-024-01183-z},
Abstract = {In this pilot study, we tested a virtual family
strengthening and mental health promotion intervention,
Coping Together (CT), during the COVID-19 pandemic. We
explored changes at the family and individual levels, as
well as mechanisms of change. Participants included 18
families (24 caregivers, 24 youth) with children aged 7 to
18 years. Community health workers delivered the 8-session
CT intervention using videoconferencing software. We used
qualitative semi-structured interviews with 14 of the
families to explore changes and mechanisms of change using a
thematic content analysis approach. We also administered
pre-post surveys with the 18 families to explore the
direction of changes, using only descriptive statistics in
this small sample. Qualitative findings supported positive
changes across family and individual level outcomes
including family functioning, relationship quality, and
individual psychosocial well-being. Results also confirmed
several hypothesized mechanisms of change with improved
communication providing the foundation for increased hope
and improved problem solving and coping. Pre-post survey
results were mixed, showing positive, but very small,
changes in family closeness, caregiver-child communication,
and levels of hope; almost no change was observed on
measures of caregiver and child mental health. Families
reported few problems at baseline quantitatively despite
qualitative descriptions of pre-intervention difficulties.
Results provide preliminary support for benefits of CT with
the most consistent improvements seen across family
relationships. Findings were mixed related to
individual-level mental health benefits. Results have
implications for revising content on mental health coping
strategies and suggest the need to revise the quantitative
measurement strategy for this non-clinical
sample.},
Doi = {10.1007/s10802-024-01183-z},
Key = {fds376689}
}
@article{fds369073,
Author = {Giusto, A and Jack, HE and Magidson, JF and Ayuku, D and Johnson, S and Lovero, K and Hankerson, SH and Sweetland, AC and Myers, B and Fortunato
Dos Santos and P and Puffer, ES and Wainberg, ML},
Title = {Global Is Local: Leveraging Global Mental-Health Methods to
Promote Equity and Address Disparities in the United
States.},
Journal = {Clinical psychological science : a journal of the
Association for Psychological Science},
Volume = {12},
Number = {2},
Pages = {270-289},
Publisher = {SAGE Publications},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1177/21677026221125715},
Abstract = {Structural barriers perpetuate mental health disparities for
minoritized US populations; global mental health (GMH) takes
an interdisciplinary approach to increasing mental health
care access and relevance. Mutual capacity building
partnerships between low and middle-income countries and
high-income countries are beginning to use GMH strategies to
address disparities across contexts. We highlight these
partnerships and shared GMH strategies through a case series
of said partnerships between Kenya-North Carolina, South
Africa-Maryland, and Mozambique-New York. We analyzed case
materials and narrative descriptions using document review.
Shared strategies across cases included: qualitative
formative work and partnership-building; selecting and
adapting evidence-based interventions; prioritizing
accessible, feasible delivery; task-sharing; tailoring
training and supervision; and mixed-method, hybrid designs.
Bidirectional learning between partners improved the use of
strategies in both settings. Integrating GMH strategies into
clinical science-and facilitating learning across
settings-can improve efforts to expand care in ways that
consider culture, context, and systems in low-resource
settings.},
Doi = {10.1177/21677026221125715},
Key = {fds369073}
}
@article{fds365795,
Author = {Puffer, ES and Johnson, SL and Quick, KN and Rieder, AD and Mansoor, M and Proeschold-Bell, RJ and Jones, S and Moore-Lawrence, S and Rasmussen,
JD and Cucuzzella, C and Burwell, F and Dowdy, L and Moore, F and Rosales,
N and Sanyal, A and Ramachandran, P and Duerr, E and Tice, L and Ayuku, D and Boone, WJ},
Title = {Family Strengthening in the Context of COVID-19: Adapting a
Community-Based Intervention from Kenya to the United
States.},
Journal = {Prevention science : the official journal of the Society for
Prevention Research},
Volume = {25},
Number = {2},
Pages = {267-278},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1007/s11121-022-01418-9},
Abstract = {COVID-19 led to widespread disruption of services that
promote family well-being. Families impacted most were those
already experiencing disparities due to structural and
systemic barriers. Existing support systems faded into the
background as families became more isolated. New approaches
were needed to deliver evidence-based, low-cost
interventions to reach families within communities. We
adapted a family strengthening intervention developed in
Kenya ("Tuko Pamoja") for the United States. We tested a
three-phase participatory adaptation process. In phase 1, we
conducted community focus groups including 11 organizations
to identify needs and a community partner. In phase 2, the
academic-community partner team collaboratively adapted the
intervention. We held a development workshop and trained
community health workers to deliver the program using an
accelerated process combining training, feedback, and
iterative revisions. In phase 3, we piloted Coping Together
with 18 families, collecting feedback through
session-specific surveys and participant focus groups.
Community focus groups confirmed that concepts from Tuko
Pamoja were relevant, and adaptation resulted in a
contextualized intervention-"Coping Together"-an 8-session
virtual program for multiple families. As in Tuko Pamoja,
communication skills are central and applied for developing
family values, visions, and goals. Problem-solving and
coping skills then equip families to reach goals, while
positive emotion-focused activities promote openness to
change. Sessions are interactive, emphasizing skills
practice. Participants reported high acceptability and
appropriateness, and focus groups suggested that most
content was understood and applied in ways consistent with
the theory of change. The accelerated reciprocal adaptation
process and intervention could apply across
resource-constrained settings.},
Doi = {10.1007/s11121-022-01418-9},
Key = {fds365795}
}
@article{fds373397,
Author = {Jaguga, F and Ott, MA and Kwobah, EK and Apondi, E and Giusto, A and Barasa, J and Kosgei, G and Rono, W and Korir, M and Puffer,
ES},
Title = {Adapting a substance use screening and brief intervention
for peer-delivery and for youth in Kenya.},
Journal = {SSM. Mental health},
Volume = {4},
Pages = {100254},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1016/j.ssmmh.2023.100254},
Abstract = {<h4>Background</h4>Substance use is a major problem among
youth in sub-Saharan Africa, yet interventions that address
this problem are scarce within the region. Screening and
brief intervention is a cost-effective, efficacious, and
easy to scale public health approach to addressing substance
use problems. We conducted a pilot study to evaluate the
feasibility of implementing a peer delivered screening and
brief intervention program for youth in Kenya. The goal of
this paper is to report on the process of adapting the
Alcohol Smoking and Substance Involvement Screening Test for
Youth- linked Brief Intervention (ASSIST-Y-linked BI)
program for peer delivery and for the Kenyan context prior
to the pilot.<h4>Methods</h4>The adaptation process was led
by a multi-disciplinary team comprised of psychiatrists,
pediatricians, and psychologists. We utilized the ADAPT-ITT
framework to adapt the ASSIST-Y-linked BI. The ADAPT-ITT
framework consists of 8 phases including Assessment,
Decision making, Adaptation, Production, Topical Experts,
Integration, Training, and Testing the evidence-based
intervention. Here, we report on phases 1-7 of the
framework. The results of the pilot testing have been
published elsewhere.<h4>Results</h4>Overall, we made surface
level adaptations to the ASSIST-Y-linked BI program such as
simplifying the language to enhance understandability. We
maintained the core components of the program i.e.,
Feedback, Responsibility, Advice, Menu of Options, Empathy,
Self-efficacy (FRAMES).<h4>Conclusions</h4>Our paper
provides information which other stakeholders planning to
implement the ASSIST-Y-linked BI for youth in sub-Saharan
Africa, could use to adapt the intervention.},
Doi = {10.1016/j.ssmmh.2023.100254},
Key = {fds373397}
}
@article{fds372411,
Author = {Knettel, BA and Oliver-Steinberg, A and Lee, MJ and Rubesin, H and Duke,
NN and Esmaili, E and Puffer, E},
Title = {Clinician and academic perspectives on expressive arts
therapy for refugee children and families: a qualitative
study},
Journal = {International Journal of Migration, Health and Social
Care},
Volume = {19},
Number = {3-4},
Pages = {260-272},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1108/IJMHSC-11-2021-0110},
Abstract = {Purpose: The refugee journey is fraught with challenges
before, during and after resettlement. There is a critical
need for mental health support upon arrival, and refugees
face language, cultural and logistical barriers. Arts-based
therapies are a promising approach to mitigating such
barriers. The purpose of this study was to elicit
professional stakeholder perspectives on mental health
challenges among refugees, the value of arts-based programs
and future directions. Design/methodology/approach: The
authors conducted three 90-min focus groups with 19
professional stakeholders in North Carolina, USA. This
included mental health professionals, professors and
community services/resettlement workers. Participants were
identified from professional networks and snowball sampling.
Each group was held by videoconference, audio recorded and
transcribed. Data were analyzed through a team-based
approach using applied thematic qualitative analysis.
Findings: Interviewees described a need for targeted,
culturally compatible mental health services for refugee
families, including trauma-informed, family-focused services
with language interpretation. Arts-based therapies were
viewed as highly acceptable and culturally responsive
approaches for understanding distress and building
resilience and less stigmatizing than traditional mental
health services. Services in schools and community settings
would further reduce stigma and minimize logistical
barriers. Participants identified needing strong, culturally
sensitive assessment tools to measure treatment progress as
a key future direction. Originality/value: The study offers
novel insights into the value of arts-based approaches and
considerations for program development. The next phase of
the project will obtain the perspectives of refugee parents
and children to understand client preferences for arts-based
therapies.},
Doi = {10.1108/IJMHSC-11-2021-0110},
Key = {fds372411}
}
@article{fds365454,
Author = {Puffer, ES and Finnegan, A and Schenk, K and Langhaug, L and Rusakaniko,
S and Choi, Y and Mahaso, S and Simmons, R and Green,
EP},
Title = {Comparing fears about paediatric HIV disclosure to the lived
experiences of parents and guardians: a prospective cohort
study.},
Journal = {Psychology & health},
Volume = {38},
Number = {12},
Pages = {1587-1605},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1080/08870446.2022.2041637},
Abstract = {<h4>Objective</h4>We aimed to: (1) follow parents and
guardians through the process of paediatric HIV disclosure
to understand how often pre-disclosure worries are realised;
and (2) estimate the effects of disclosure on child,
caregiver, and family well-being.<h4>Design</h4>We conducted
a 12-month prospective cohort study in Zimbabwe with 123
primary caregivers of children ages 9 to 15 years who were
HIV positive but did not know their serostatus at baseline.
By the end of the study period 65 caregivers reported that
their child learned his or her HIV-positive status.<h4>Main
outcome measures</h4>We used three waves of data to compare
caregivers' pre-disclosure worries to post-disclosure
reports and to characterise associations between disclosure
and well-being of the child (Strengths and Difficulties
Questionnaire), caregiver (Patient Health Questionnaire-9),
and family (Family Relationship Quality) over
time.<h4>Results</h4>Caregivers' pre-disclosure worries and
fears about how their child would react to disclosure of
their HIV status largely went unrealised. Furthermore, we
did not find strong evidence of clinically-important
increases in problems on average following
disclosure.<h4>Conclusion</h4>Findings support the call to
identify supportive intervention strategies that address
caregiver fears at the beginning of the disclosure
process.},
Doi = {10.1080/08870446.2022.2041637},
Key = {fds365454}
}
@article{fds374235,
Author = {Jaguga, F and Kwobah, EK and Giusto, A and Apondi, E and Barasa, J and Korir, M and Rono, W and Kosgei, G and Puffer, E and Ott,
M},
Title = {Feasibility and acceptability of a peer provider delivered
substance use screening and brief intervention program for
youth in Kenya.},
Journal = {BMC public health},
Volume = {23},
Number = {1},
Pages = {2254},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1186/s12889-023-17146-w},
Abstract = {<h4>Background</h4>Youth in sub-Saharan Africa are at high
risk of substance use yet lack access to substance use
interventions. The goal of this project was to evaluate the
feasibility and acceptability of a peer-delivered,
single-session substance use screening and brief
intervention program for youth in Kenya.<h4>Methods</h4>This
was a convergent parallel mixed methods study utilizing both
quantitative and qualitative approaches. Two trained peer
providers administered the screening and brief intervention
program to 100 youth aged 15-24 years. To evaluate the
implementation of the intervention, we collected
quantitative and qualitative data. Feasibility and
acceptability were quantitatively assessed using the
Dissemination and Implementation Measures. Fidelity was
assessed by rating all 100 audio-recorded sessions using a
checklist. To obtain qualitative feedback on the
intervention, we conducted five focus group discussions with
25 youths and six semi-structured interviews with two peer
providers and four clinic leaders. The semi-structured
interviews were guided by the Consolidated Framework for
Implementation Research. Quantitative data was analyzed via
descriptive statistics using STATA. Qualitative data was
analyzed using thematic analysis with NVIVO.<h4>Results</h4>The
lifetime prevalence of any substance use was 50%. The mean
level of acceptability of the intervention from the
perspective of the youth was 3.53 (SD 0.15), meaning that
the youth found the intervention to be acceptable "a lot" of
the time. Mean levels of implementation outcomes
(acceptability, adoption, Acceptability, Appropriateness,
Feasibility, Reach/access, Organizational climate, General
leadership skills, and Sustainability) as rated by peer
providers and clinic staff ranged between 2.61 ("a moderate
amount") and 4.0 ("a lot"). In qualitative data, youth
reported that the intervention was helpful and useful in
enabling them to stop or reduce substance use. The peer
providers felt that the intervention was easy to implement,
while the clinic leaders felt that available resources were
adequate, and that the intervention aligned well with the
goals of the clinic.<h4>Conclusion</h4>Our findings suggest
that the peer-delivered screening and brief intervention
program was perceived as acceptable to the youth and
feasible to implement.<h4>Trial registration</h4>NCT04998045
Registration date: 10/08/2021.},
Doi = {10.1186/s12889-023-17146-w},
Key = {fds374235}
}
@article{fds372412,
Author = {Quick, KN and Vissoci, JRN and Green, EP and Chase, RM and Puffer,
ES},
Title = {Adaptation and Evaluation of a Picture-Based Measure of
Parent Discipline},
Journal = {Journal of Child and Family Studies},
Volume = {32},
Number = {10},
Pages = {2901-2914},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1007/s10826-023-02640-x},
Abstract = {Harsh parenting behaviors are some of the most commonly used
discipline practices in the United States but are often
difficult to measure. Self-report instruments are the most
used method of assessing parenting behaviors, but likely
result in response biases due to their methodological
shortcomings. This study aimed to provide a viable
alternative to traditional self-report surveys used to
evaluate parenting practices with lower social desirability
and lower literacy requirements. Our primary objectives were
to adapt the Harsh Discipline Preference Discrete Choice
Experiment (HDP-DCE), a picture-based measure originally
developed for Liberia, for use with an American population,
and evaluate its psychometric evidence of reliability and
validity. We first adapted items through an iterative
process of collecting feedback from 97 parents and 10
experts through focus groups and surveys to generate clear
and acceptable images to elicit preferences for discipline
strategies. We then administered the measure to 439 parents
to explore the internal structure of the measure and
evaluate multiple indicators of reliability and validity. An
exploratory factor analysis resulted in three potential
factor-solutions, with the three-factor solution explaining
the most variance and being the most theoretically sound.
Analyses also demonstrated that the HDP-DCE has excellent
internal consistency, good test-retest reliability, and good
convergent and discriminant validity. Given these results
the HDP-DCE could be a useful alternative or complement to
traditional self-report tools in research and clinical
work.},
Doi = {10.1007/s10826-023-02640-x},
Key = {fds372412}
}
@article{fds373561,
Author = {Venturo-Conerly, K and Osborn, TL and Puffer, ES and Weisz, J and van
der Markt, A},
Title = {RE: Do no harm: can school mental health interventions cause
iatrogenic harm?},
Journal = {BJPsych bulletin},
Volume = {47},
Number = {5},
Pages = {300-301},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1192/bjb.2023.65},
Doi = {10.1192/bjb.2023.65},
Key = {fds373561}
}
@article{fds373562,
Author = {Johnson, S and Quick, KN and Rieder, AD and Rasmussen, JD and Sanyal, A and Green, EP and Duerr, E and Nagy, GA and Puffer, ES},
Title = {Social Vulnerability, COVID-19, Racial Violence, and
Depressive Symptoms: a Cross-sectional Study in the Southern
United States.},
Journal = {Journal of racial and ethnic health disparities},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1007/s40615-023-01831-y},
Abstract = {<h4>Background</h4>In March 2020, the novel 2019 coronavirus
disease (COVID-19) was declared a pandemic. In May 2020,
George Floyd was murdered, catalyzing a national racial
reckoning. In the Southern United States, these events
occurred in the context of a history of racism and high
rates of poverty and discrimination, especially among
racially and ethnically minoritized populations.<h4>Objectives</h4>In
this study, we examine social vulnerabilities, the perceived
impacts of COVID-19 and the national racial reckoning, and
how these are associated with depression symptoms in the
South.<h4>Methods</h4>Data were collected from 961 adults
between June and November 2020 as part of an online survey
study on family well-being during COVID-19. The sample was
majority female (87.2%) and consisted of 661 White
participants, 143 Black participants, and 157 other racial
and ethnic minoritized participants. Existing social
vulnerability, perceived impact of COVID-19 and racial
violence and protests on families, and depressive symptoms
were assessed. Hierarchical regression analysis was used to
predict variance in depressive symptoms.<h4>Results</h4>Half
of the sample (52%) reported a negative impact of COVID-19,
and 66% reported a negative impact of national racial
violence/protests. Depressive symptoms were common with
49.8% meeting the cutoff for significant depressive
symptoms; Black participants had lower levels of depressive
symptoms. Results from the hierarchical regression analysis
indicate social vulnerabilities and the perceived negative
impact of COVID-19 and racial violence/protests each
contribute to variance in depressive symptoms. Race-specific
sensitivity analysis clarified distinct patterns in
predictors of depressive symptoms.<h4>Conclusion</h4>People
in the South report being negatively impacted by the
confluence of the COVID-19 pandemic and the emergence of
racial violence/protests in 2020, though patterns differ by
racial group. These events, on top of pre-existing social
vulnerabilities, help explain depressive symptoms in the
South during 2020.},
Doi = {10.1007/s40615-023-01831-y},
Key = {fds373562}
}
@article{fds371128,
Author = {Kim, AW and Rieder, AD and Cooper-Vince, CE and Kakuhikire, B and Baguma, C and Satinsky, EN and Perkins, JM and Kiconco, A and Namara,
EB and Rasmussen, JD and Ashaba, S and Bangsberg, DR and Tsai, AC and Puffer, ES},
Title = {Maternal adverse childhood experiences, child mental health,
and the mediating effect of maternal depression: A
cross-sectional, population-based study in rural,
southwestern Uganda.},
Journal = {American journal of biological anthropology},
Volume = {182},
Number = {1},
Pages = {19-31},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1002/ajpa.24758},
Abstract = {<h4>Objectives</h4>This study aimed to examine the
intergenerational effects of maternal adverse childhood
experiences (ACEs) and child mental health outcomes in rural
Uganda, as well as the potentially mediating role of
maternal depression in this pathway. Additionally, we sought
to test the extent to which maternal social group membership
attenuated the mediating effect of maternal depression on
child mental health.<h4>Methods</h4>Data come from a
population-based cohort of families living in the Nyakabare
Parish, a rural district in southwestern Uganda. Between
2016 and 2018, mothers completed surveys about childhood
adversity, depressive symptoms, social group membership, and
their children's mental health. Survey data were analyzed
using causal mediation and moderated-mediation
analysis.<h4>Results</h4>Among 218 mother-child pairs, 61
mothers (28%) and 47 children (22%) showed symptoms meeting
cutoffs for clinically significant psychological distress.
In multivariable linear regression models, maternal ACEs had
a statistically significant association with severity of
child conduct problems, peer problems, and total child
difficulty scores. Maternal depression mediated the
relationship between maternal ACEs and conduct problems,
peer problems, and total difficulty, but this mediating
effect was not moderated by maternal group
membership.<h4>Conclusions</h4>Maternal depression may act
as a potential mechanism linking maternal childhood
adversity with poor child mental health in the next
generation. Within a context of elevated rates of
psychiatric morbidity, high prevalence of childhood
adversity, and limited healthcare and economic
infrastructures across Uganda, these results emphasize the
prioritization of social services and mental health
resources for rural Ugandan families.},
Doi = {10.1002/ajpa.24758},
Key = {fds371128}
}
@article{fds371129,
Author = {Giusto, A and Vander Missen and MR and Kosgei, G and Njiriri, F and Puffer,
E and Kamaru Kwobah and E and Barasa, J and Turissini, M and Rasmussen, J and Ott, M and Binayo, J and Rono, W and Jaguga, F},
Title = {Peer-delivered Problem-solving Therapy for Adolescent Mental
Health in Kenya: Adaptation for Context and Training of
Peer-counselors.},
Journal = {Research on child and adolescent psychopathology},
Volume = {51},
Number = {9},
Pages = {1243-1256},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1007/s10802-023-01075-8},
Abstract = {Peer-delivered interventions for adolescent mental health
can help address poor access to mental health interventions.
Questions remain about how interventions can be adapted for
peer delivery and whether peers can be trained. In this
study, we adapted problem solving therapy (PST) for
peer-delivery with adolescents in Kenya and explored whether
peer counselors can be trained in PST. We adapted treatment
prior to and during training using the Cultural Adaptation
and Contextualization for Implementation framework. Nine
peer counselors (Ages 20-24) were selected and trained over
10 days. Peer competencies and knowledge were measured
pre-post using a written exam, a written case study, and
role plays rated using a standardized competency measure. We
chose a version of PST used in India with secondary school
adolescents originally delivered by teachers. All materials
were translated into Kiswahili. Language and format were
adapted to Kenyan adolescents as well as for delivery by
peers with a focus on understandability and relevance (e.g.,
noting shared experience). Metaphors, examples, and visual
materials were adapted for the context to reflect the
culture and vernacular of Kenyan youth. Peer counselors were
able to be trained in PST. Pre-post competencies and
understanding of content showed improvements with peers
minimally meeting patient needs (pre) on average to
moderate/fully meeting patient needs (post). Post-training
written exam score showed an average 90% correct. There is
an adapted version of PST for Kenyan adolescents and peer
delivery. Peer counselors can be trained to deliver a
5-session PST in a community context.},
Doi = {10.1007/s10802-023-01075-8},
Key = {fds371129}
}
@article{fds372672,
Author = {Kaiser, BN and Kaufman, J and Wall, JT and Healy, EAF and Ayuku, D and Aarons, GA and Puffer, ES},
Title = {Assessing ad-hoc adaptations' alignment with therapeutic
goals: a qualitative study of lay counselor-delivered family
therapy in Eldoret, Kenya.},
Journal = {Implementation science communications},
Volume = {4},
Number = {1},
Pages = {105},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1186/s43058-023-00477-5},
Abstract = {<h4>Background</h4>A key question in implementation science
is how to balance adaptation and fidelity in translating
interventions to new settings. There is growing consensus
regarding the importance of planned adaptations to deliver
interventions in contextually sensitive ways. However, less
research has examined ad-hoc adaptations, or those that
occur spontaneously in the course of intervention delivery.
A key question is whether ad-hoc adaptations ultimately
contribute to or detract from intervention goals. This study
aimed to (a) identify ad-hoc adaptations made during
delivery of a family therapy intervention and (b) assess
whether they promoted or interrupted intervention
goals.<h4>Methods</h4>Tuko Pamoja (Swahili: "We are
Together") is an evidence-informed family therapy
intervention aiming to improve family dynamics and mental
health in Kenya. Tuko Pamoja employs a task-shifting model,
delivered by lay counselors who are afforded a degree of
flexibility in presenting content and in practices they use
in sessions. We used transcripts of therapy sessions with 14
families to examine ad-hoc adaptations used by counselors.
We first identified and characterized ad-hoc adaptations
through a team-based code development, coding, and code
description process. Then, we evaluated to what extent
ad-hoc adaptations promoted the principles and strategies of
the intervention ("TP-promoting"), disrupted them
("TP-interrupting"), or neither ("TP-neutral"). To do this,
we first established inter-coder agreement on application of
these categories with verification by the intervention
developer. Then, coders categorized ad-hoc adaptation text
segments as TP-promoting, TP-interrupting, or
TP-neutral.<h4>Results</h4>Ad-hoc adaptations were frequent
and included (in decreasing order): incorporation of
religious content, exemplars/role models, community dynamics
and resources, self-disclosure, and metaphors/proverbs.
Ad-hoc adaptations were largely TP-promoting (49%) or
neutral (39%), but practices were TP-interrupting 12% of the
time. TP-interrupting practices most often occurred within
religious content and exemplars/role models, which were also
the most common practices overall.<h4>Conclusion</h4>Extra
attention is needed during planned adaptation, training, and
supervision to promote intervention-aligned use of common
ad-hoc adaptation practices. Discussing them in trainings
can provide guidance for lay providers on how best to
incorporate ad-hoc adaptations during delivery. Future
research should evaluate whether well-aligned ad-hoc
adaptations improve therapeutic outcomes.<h4>Trial
registration</h4>Pilot trial registered at
clinicaltrials.gov (C0058).},
Doi = {10.1186/s43058-023-00477-5},
Key = {fds372672}
}
@article{fds372673,
Author = {Joshi, D and Aschner, A and Atkinson, L and Halili-Sychangco, D and Duku, E and Puffer, ES and Rieder, A and Tonmyr, L and Gonzalez,
A},
Title = {Predictors of harsh parenting practices and inter-partner
conflict during the COVID-19 pandemic in Ontario, Canada: a
cross-sectional analysis from the Ontario Parent
Survey.},
Journal = {BMJ open},
Volume = {13},
Number = {8},
Pages = {e066840},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1136/bmjopen-2022-066840},
Abstract = {<h4>Objectives</h4>Guided by the bioecological model, the
purpose of this study was to examine the associations of (1)
individual level factors (sociodemographic, health behaviour
and mental health), (2) family (micro) level COVID-19
experiences (difficulty with household management, managing
child mood and behaviour, and pandemic-related positive
experiences) and (3) community (macro) level factors
(residential instability, ethnic concentration, material
deprivation and dependency, an indicator of age and labour
force) with harsh parenting practices and inter-partner
conflict during the early lockdown of the COVID-19 pandemic
in Ontario, Canada.<h4>Design</h4>A cross-sectional analysis
of data from the Ontario Parent Survey.<h4>Setting</h4>A
convenience sample of 7451 caregivers living in Ontario,
Canada, at the time of baseline data collection (May-June
2020).<h4>Participants</h4>Caregivers aged 18 years and
older with children 17 years or younger.<h4>Outcome
measures</h4>Parenting practices over the past 2 months
was assessed using a published modification of the Parenting
Scale. The frequency of inter-partner conflict over the past
month was assessed using the Marital Conflict
scale.<h4>Results</h4>Individual (sociodemographic factors,
alcohol use, and higher depressive and anxiety symptoms) and
family (difficulties with managing the household and child
mood and behaviour) level factors were positively associated
with inter-partner conflict and harsh parenting practices.
Having fewer positive experiences (eg, performing activities
with children), and economic adversity at the family level
were positively associated with inter-partner conflict but
inversely associated with harsh parenting. At the community
level, residential instability was negatively associated
with harsh parenting practices.<h4>Conclusions</h4>Individual
and family level factors were associated with harsh
parenting and inter-partner conflict. The associations of
fewer positive experiences and economic hardship with harsh
parenting practices may be more complex than initially
thought. Efforts that raise awareness and address caregiver
mental health concerns are needed as part of the pandemic
response to promote positive inter-partner and parent-child
interactions.},
Doi = {10.1136/bmjopen-2022-066840},
Key = {fds372673}
}
@article{fds368902,
Author = {Johnson, SL and Rieder, A and Green, EP and Finnegan, A and Chase, RM and Zayzay, J and Puffer, ES},
Title = {Parenting in a conflict-affected setting: Discipline
practices, parent-child interactions, and parenting stress
in Liberia.},
Journal = {Journal of family psychology : JFP : journal of the Division
of Family Psychology of the American Psychological
Association (Division 43)},
Volume = {37},
Number = {3},
Pages = {283-294},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1037/fam0001041},
Abstract = {Children in conflict-affected settings are at increased risk
for exposure to violence, placing particular importance on
caregiving environments. This study first describes
parenting in urban Liberia by evaluating parent-child
interactions, the use and acceptance of harsh and nonharsh
discipline, discipline preferences, and the co-occurrence of
positive interactions and harsh discipline. The relationship
between parenting stress and harsh discipline attitudes and
behaviors is then tested. Participants included 813 parents
with a child aged 3 or 4 years old. A quantitative survey
battery assessed parent-child interactions; discipline
practices, preferences, and attitudes; and parenting stress.
Parents reported frequent use and high acceptance of
nonharsh discipline, as well as frequent positive
interactions with their child. Though parents reported less
frequent use and low acceptance of harsh discipline,
preference for harsh discipline-based on hypothetical
situations rather than self-report-was common. There was
co-occurrence of frequent positive interactions and frequent
harsh discipline, with one third reporting high frequency of
both. Regression analysis revealed greater parenting stress
(β = .15, <i>t</i> = 4.49, <i>p</i> < .001) and stronger
acceptance of harsh discipline (β = .47, <i>t</i> = 15.49,
<i>p</i> < .001) were associated with more frequent harsh
discipline. Acceptance of harsh discipline interacted with
parenting stress to predict the use of harsh discipline (β
= -.09, <i>t</i> = -3.09, <i>p</i> < .01). Among parents
with lowest average acceptance of harsh practices, stress
predicted more frequent harsh discipline, but acceptance did
not moderate the association for those who are most
accepting of harsh practices. Building on existing parenting
strengths and addressing parenting stress could promote
nurturing caregiving in conflict-affected settings.
(PsycInfo Database Record (c) 2023 APA, all rights
reserved).},
Doi = {10.1037/fam0001041},
Key = {fds368902}
}
@article{fds369706,
Author = {Sim, A and Puffer, E and Ahmad, A and Hammad, L and Georgiades,
K},
Title = {Resettlement, mental health, and coping: a mixed methods
survey with recently resettled refugee parents in
Canada.},
Journal = {BMC public health},
Volume = {23},
Number = {1},
Pages = {386},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1186/s12889-023-15300-y},
Abstract = {<h4>Background</h4>Resettlement experiences of refugee
parents are under-researched despite evidence indicating
higher risk of poor mental health. The current study
integrates family systems and social determinants of refugee
mental health frameworks to examine: (1) Refugee parents'
experiences of resettlement stressors and mental health; (2)
Perceived impacts of resettlement stressors on individual
and family indicators of well-being; and (3) Refugee
parents' coping strategies and resources.<h4>Methods</h4>The
study draws on data from a mixed methods survey conducted
with 40 Government-Assisted Refugee parents who had
resettled to Hamilton, Canada within the past 4 years.
Quantitative and qualitative data were analyzed separately
and then integrated at the results stage using a weaving
approach.<h4>Results</h4>Results indicate significant
exposure to economic and social stressors across multiple
domains of daily life, as well as high levels of parental
psychological distress. Parents drew linkages between
resettlement stressors and negative mental health impacts
that were compounded by intersecting risk factors of ill
health, caregiving burden, single parenthood, and low levels
of education and literacy. Most parents rated themselves as
coping well or very well and described various coping
strategies such as positive reframing, problem solving,
planning, and turning to religion. Quantitative and
qualitative findings indicate high frequency of positive
parent-child interaction and low frequency of family
conflict, and highlight the importance of family as a
protective resource for coping with adversity. Exploratory
regression analyses suggest that longer stay in Canada,
poorer self-rated health, higher levels of resettlement
stressors, and more conflict between adults in the household
may be associated with greater psychological
distress.<h4>Conclusion</h4>Study findings highlight both
the resilience of refugee parents and the psychological toll
of navigating their families through a new and challenging
environment. Policies and programs to provide comprehensive
social and economic supports to refugees beyond the first
one to two years after arrival are necessary to mitigate the
mental health impacts of displacement over time and
strengthen individual and family resilience. Such programs
should include culturally responsive and family-based models
of mental health care that acknowledge collective
experiences and impacts of adversity, as well as harness
family resources to overcome past and present
challenges.},
Doi = {10.1186/s12889-023-15300-y},
Key = {fds369706}
}
@article{fds373960,
Author = {Sim, A and Jirapramukpitak, T and Eagling-Peche, S and Lwin, KZ and Melendez-Torres, GJ and Gonzalez, A and Oo, NN and Castello Mitjans,
I and Soan, M and Punpuing, S and Lee, C and Chuenglertsiri, P and Moo, T and Puffer, E},
Title = {A film-based intervention to reduce child maltreatment among
migrant and displaced families from Myanmar: Protocol of a
pragmatic cluster randomized controlled trial.},
Journal = {PloS one},
Volume = {18},
Number = {10},
Pages = {e0293623},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1371/journal.pone.0293623},
Abstract = {<h4>Background</h4>Child maltreatment is a global public
health crisis with negative consequences for physical and
mental health. Children in low- and middle-income countries
(LMIC)-particularly those affected by poverty, armed
conflict, and forced migration-may be at increased risk of
maltreatment due to heightened parental distress and
disruptions to social support networks. Parenting
interventions have been shown to reduce the risk of child
maltreatment as well as improve a range of caregiver and
child outcomes, yet large-scale implementation remains
limited in low-resource displacement settings. This study
will examine the impact of an entertainment-education
narrative film intervention on reducing physical and
emotional abuse and increasing positive parenting among
migrant and displaced families from Myanmar living in
Thailand.<h4>Method</h4>The study is a pragmatic,
superiority cluster randomized controlled trial with
approximately 40 communities randomized to the intervention
or treatment as usual arms in a 1:1 ratio. Participating
families in the intervention arm will be invited to attend a
community screening of the film intervention and a
post-screening discussion, as well as receive a poster
depicting key messages from the film. Primary outcomes are
changes in physical abuse, emotional abuse, and positive
parenting behaviour. Secondary outcomes include caregiver
knowledge of positive parenting, caregiver attitudes towards
harsh punishment, caregiver psychological distress, and
family functioning. Outcomes will be assessed at 3 time
points: baseline, 4 weeks post-intervention, and 4-month
follow up. A mixed methods process evaluation will be
embedded within the trial to assess intervention delivery,
acceptability, perceived impacts, and potential mechanisms
of change.<h4>Discussion</h4>To our knowledge, this study
will be the first randomized controlled trial evaluation of
a film-based intervention to reduce child maltreatment among
migrant and displaced families in a LMIC. An integrated
knowledge translation approach will inform uptake of study
findings and application to potential scale up pending
evaluation results.<h4>Trial registration</h4>The study was
prospectively registered with the Thai Clinical Trials
Registry on 22 February 2023 (TCTR20230222005).},
Doi = {10.1371/journal.pone.0293623},
Key = {fds373960}
}
@article{fds370315,
Author = {Satinsky, EN and Kakuhikire, B and Baguma, C and Cooper-Vince, CE and Rasmussen, JD and Ashaba, S and Perkins, JM and Ahereza, P and Ayebare,
P and Kim, AW and Puffer, ES and Tsai, AC},
Title = {Caregiver preferences for physically harsh discipline of
children in rural Uganda},
Journal = {Journal of Family Violence},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1007/s10896-023-00536-4},
Abstract = {Purpose: Physically harsh discipline is associated with poor
developmental outcomes among children. These practices are
more prevalent in areas experiencing poverty and resource
scarcity, including in low- and middle-income countries.
Designed to limit social desirability bias, this
cross-sectional study in rural Uganda estimated caregiver
preferences for physically harsh discipline; differences by
caregiver sex, child sex, and setting; and associations with
indicators of household economic stress and insecurity.
Method: Three-hundred-fifty adult caregivers were shown six
hypothetical pictographic scenarios depicting children
whining, spilling a drink, and kicking a caregiver. Girls
and boys were depicted engaging in each of the three
behaviors. Approximately half of the participants were shown
scenes from a market setting and half were shown scenes from
a household setting. For each scenario, caregivers reported
the discipline strategy they would use (time out, beating,
discussing, yelling, ignoring, slapping). Results: Two
thirds of the participants selected a physically harsh
discipline strategy (beating, slapping) at least once. Women
selected more physically harsh discipline strategies than
men (b = 0.40; 95% confidence interval [CI], 0.26 to 0.54).
Participants shown scenes from the market selected fewer
physically harsh discipline strategies than participants
shown scenes from the household (b = -0.51; 95% CI, -0.69 to
-0.33). Finally, caregivers selected more physically harsh
discipline strategies in response to boys than girls.
Indicators of economic insecurity were inconsistently
associated with preferences for physically harsh discipline.
Conclusions: The high prevalence of physically harsh
discipline preferences warrant interventions aimed at
reframing caregivers’ approaches to discipline.},
Doi = {10.1007/s10896-023-00536-4},
Key = {fds370315}
}
@article{fds371298,
Author = {Barnett, ML and Puffer, ES and Ng, LC and Jaguga,
F},
Title = {Effective training practices for non-specialist providers to
promote high-quality mental health intervention delivery: A
narrative review with four case studies from Kenya,
Ethiopia, and the United States.},
Journal = {Global mental health (Cambridge, England)},
Volume = {10},
Pages = {e26},
Publisher = {Cambridge University Press (CUP)},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1017/gmh.2023.19},
Abstract = {Mental health needs and disparities are widespread and have
been exacerbated by the COVID-19 pandemic, with the greatest
burden being on marginalized individuals worldwide. The
World Health Organization developed the Mental Health Gap
Action Programme to address growing global mental health
needs by promoting task sharing in the delivery of
psychosocial and psychological interventions. However,
little is known about the training needed for
non-specialists to deliver these interventions with high
levels of competence and fidelity. This article provides a
brief conceptual overview of the evidence concerning the
training of non-specialists carrying out task-sharing
psychosocial and psychological interventions while utilizing
illustrative case studies from Kenya, Ethiopia, and the
United States to highlight findings from the literature. In
this article, the authors discuss the importance of
tailoring training to the skills and needs of the
non-specialist providers and their roles in the delivery of
an intervention. This narrative review with four case
studies advocates for training that recognizes the expertise
that non-specialist providers bring to intervention
delivery, including how they promote culturally responsive
care within their communities.},
Doi = {10.1017/gmh.2023.19},
Key = {fds371298}
}
@article{fds375963,
Author = {Maloney, CA and Wall, T and Giusto, AM and Chase, RM and Finnegan, A and Sim, A and Zayzay, JO and Puffer, ES},
Title = {Early Childhood Parenting Programs and Community
Peacebuilding Behaviors: A Case Study From Postconflict
Liberia},
Journal = {Peace and Conflict},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1037/pac0000717},
Abstract = {Despite the connection between early childhood development
(ECD) and later behavioral outcomes, peacebuilding
frameworks have only recently begun to explore pathways
through which ECD programs promote peace in community
contexts. Recent literature theorizes that ECD interventions
may spill over from family to community interactions, which
is particularly important in areas affected by conflict. The
current case study explored qualitative outcomes associated
with peacebuilding behaviors across a randomized controlled
trial of Parents Make the Difference, a parenting program in
postconflict Liberia. Parents or primary caregivers of
children aged 3–5 years (N = 813) attended 10 weekly
sessions, with 75 completing follow-up interviews.
Participants described engaging in prosocial behaviors in
the context of their community following program completion,
such as decreased personal conflict and empowerment to
mediate conflict between peers. Findings highlight improved
community relationships in promoting peace among adults and
modeling these behaviors for children during a critical
period of development.},
Doi = {10.1037/pac0000717},
Key = {fds375963}
}
%% Rasmussen, Justin
@article{fds376855,
Author = {Rasmussen, JM and Johnson, SL and Ochieng, Y and Jaguga, F and Green, E and Puffer, E},
Title = {Congregation leader and member discussions in a church-based
family strengthening, mental health promotion, and HIV
prevention trial: Intervention},
Journal = {Cambridge Prisms: Global Mental Health},
Pages = {1-36},
Publisher = {Cambridge University Press (CUP)},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1017/gmh.2024.44},
Doi = {10.1017/gmh.2024.44},
Key = {fds376855}
}
@article{fds373402,
Author = {Johnson, SL and Rasmussen, JM and Mansoor, M and Ibrahim, H and Rono, W and Goel, P and Vissoci, JRN and Von Isenburg and M and Puffer,
ES},
Title = {Correlates of Intimate Partner Violence Victimization and
Perpetration in Adolescents and Young Adults in Sub-Saharan
Africa: A Systematic Review.},
Journal = {Trauma, violence & abuse},
Volume = {25},
Number = {2},
Pages = {1168-1183},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1177/15248380231173428},
Abstract = {Intimate partner violence (IPV) is a global public health
crisis with long-term adverse consequences for both victims
and perpetrators. Patterns of violence often begin during
adolescence, yet most interventions target adult
relationships. A systematic review was conducted to identify
correlates of IPV victimization and perpetration among
adolescents and young adults in sub-Saharan Africa (SSA).
Eligible studies included participants 10 to 24 years old,
took place in SSA, and tested a statistical association
between a correlate and an IPV outcome. Correlates were
defined as any condition or characteristic associated with
statistically significant increased or decreased risk of IPV
victimization or perpetration. PsycInfo, PubMed, Embase, and
African Index Medicus were searched and included studies
published between January 1, 2000 and February 4, 2022. The
search resulted in 3,384 original studies, of which 55 met
inclusion criteria and were analyzed. Correlates were first
qualitatively synthesized by developmental period (e.g.,
early adolescence, older adolescence, and young adulthood)
and then organized in a conceptual framework by correlate
type (e.g., socio-demographic; health, behavior, and
attitudes; relational; or contextual). Over two decades of
literature reveals variability in evidence by developmental
period but also substantial overlap in the correlates of
victimization and perpetration. This review identifies
multiple points for intervention and results suggest the
urgent need for earlier, developmentally appropriate
prevention efforts among younger adolescents as well as
combined approaches that target both victimization and
perpetration of IPV.},
Doi = {10.1177/15248380231173428},
Key = {fds373402}
}
@article{fds376693,
Author = {Johnson, SL and Rieder, AD and Rasmussen, JM and Mansoor, M and Quick,
KN and Proeschold-Bell, RJ and Coping Together Team, and Boone, WJ and Puffer, ES},
Title = {A Pilot Study of the Coping Together Virtual Family
Intervention: Exploring Changes in Family Functioning and
Individual Well-Being.},
Journal = {Research on child and adolescent psychopathology},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1007/s10802-024-01183-z},
Abstract = {In this pilot study, we tested a virtual family
strengthening and mental health promotion intervention,
Coping Together (CT), during the COVID-19 pandemic. We
explored changes at the family and individual levels, as
well as mechanisms of change. Participants included 18
families (24 caregivers, 24 youth) with children aged 7 to
18 years. Community health workers delivered the 8-session
CT intervention using videoconferencing software. We used
qualitative semi-structured interviews with 14 of the
families to explore changes and mechanisms of change using a
thematic content analysis approach. We also administered
pre-post surveys with the 18 families to explore the
direction of changes, using only descriptive statistics in
this small sample. Qualitative findings supported positive
changes across family and individual level outcomes
including family functioning, relationship quality, and
individual psychosocial well-being. Results also confirmed
several hypothesized mechanisms of change with improved
communication providing the foundation for increased hope
and improved problem solving and coping. Pre-post survey
results were mixed, showing positive, but very small,
changes in family closeness, caregiver-child communication,
and levels of hope; almost no change was observed on
measures of caregiver and child mental health. Families
reported few problems at baseline quantitatively despite
qualitative descriptions of pre-intervention difficulties.
Results provide preliminary support for benefits of CT with
the most consistent improvements seen across family
relationships. Findings were mixed related to
individual-level mental health benefits. Results have
implications for revising content on mental health coping
strategies and suggest the need to revise the quantitative
measurement strategy for this non-clinical
sample.},
Doi = {10.1007/s10802-024-01183-z},
Key = {fds376693}
}
@article{fds373405,
Author = {Puffer, ES and Johnson, SL and Quick, KN and Rieder, AD and Mansoor, M and Proeschold-Bell, RJ and Jones, S and Moore-Lawrence, S and Rasmussen,
JD and Cucuzzella, C and Burwell, F and Dowdy, L and Moore, F and Rosales,
N and Sanyal, A and Ramachandran, P and Duerr, E and Tice, L and Ayuku, D and Boone, WJ},
Title = {Family Strengthening in the Context of COVID-19: Adapting a
Community-Based Intervention from Kenya to the United
States.},
Journal = {Prevention science : the official journal of the Society for
Prevention Research},
Volume = {25},
Number = {2},
Pages = {267-278},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1007/s11121-022-01418-9},
Abstract = {COVID-19 led to widespread disruption of services that
promote family well-being. Families impacted most were those
already experiencing disparities due to structural and
systemic barriers. Existing support systems faded into the
background as families became more isolated. New approaches
were needed to deliver evidence-based, low-cost
interventions to reach families within communities. We
adapted a family strengthening intervention developed in
Kenya ("Tuko Pamoja") for the United States. We tested a
three-phase participatory adaptation process. In phase 1, we
conducted community focus groups including 11 organizations
to identify needs and a community partner. In phase 2, the
academic-community partner team collaboratively adapted the
intervention. We held a development workshop and trained
community health workers to deliver the program using an
accelerated process combining training, feedback, and
iterative revisions. In phase 3, we piloted Coping Together
with 18 families, collecting feedback through
session-specific surveys and participant focus groups.
Community focus groups confirmed that concepts from Tuko
Pamoja were relevant, and adaptation resulted in a
contextualized intervention-"Coping Together"-an 8-session
virtual program for multiple families. As in Tuko Pamoja,
communication skills are central and applied for developing
family values, visions, and goals. Problem-solving and
coping skills then equip families to reach goals, while
positive emotion-focused activities promote openness to
change. Sessions are interactive, emphasizing skills
practice. Participants reported high acceptability and
appropriateness, and focus groups suggested that most
content was understood and applied in ways consistent with
the theory of change. The accelerated reciprocal adaptation
process and intervention could apply across
resource-constrained settings.},
Doi = {10.1007/s11121-022-01418-9},
Key = {fds373405}
}
@article{fds373563,
Author = {Johnson, S and Quick, KN and Rieder, AD and Rasmussen, JD and Sanyal, A and Green, EP and Duerr, E and Nagy, GA and Puffer, ES},
Title = {Social Vulnerability, COVID-19, Racial Violence, and
Depressive Symptoms: a Cross-sectional Study in the Southern
United States.},
Journal = {Journal of racial and ethnic health disparities},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1007/s40615-023-01831-y},
Abstract = {<h4>Background</h4>In March 2020, the novel 2019 coronavirus
disease (COVID-19) was declared a pandemic. In May 2020,
George Floyd was murdered, catalyzing a national racial
reckoning. In the Southern United States, these events
occurred in the context of a history of racism and high
rates of poverty and discrimination, especially among
racially and ethnically minoritized populations.<h4>Objectives</h4>In
this study, we examine social vulnerabilities, the perceived
impacts of COVID-19 and the national racial reckoning, and
how these are associated with depression symptoms in the
South.<h4>Methods</h4>Data were collected from 961 adults
between June and November 2020 as part of an online survey
study on family well-being during COVID-19. The sample was
majority female (87.2%) and consisted of 661 White
participants, 143 Black participants, and 157 other racial
and ethnic minoritized participants. Existing social
vulnerability, perceived impact of COVID-19 and racial
violence and protests on families, and depressive symptoms
were assessed. Hierarchical regression analysis was used to
predict variance in depressive symptoms.<h4>Results</h4>Half
of the sample (52%) reported a negative impact of COVID-19,
and 66% reported a negative impact of national racial
violence/protests. Depressive symptoms were common with
49.8% meeting the cutoff for significant depressive
symptoms; Black participants had lower levels of depressive
symptoms. Results from the hierarchical regression analysis
indicate social vulnerabilities and the perceived negative
impact of COVID-19 and racial violence/protests each
contribute to variance in depressive symptoms. Race-specific
sensitivity analysis clarified distinct patterns in
predictors of depressive symptoms.<h4>Conclusion</h4>People
in the South report being negatively impacted by the
confluence of the COVID-19 pandemic and the emergence of
racial violence/protests in 2020, though patterns differ by
racial group. These events, on top of pre-existing social
vulnerabilities, help explain depressive symptoms in the
South during 2020.},
Doi = {10.1007/s40615-023-01831-y},
Key = {fds373563}
}
@article{fds373399,
Author = {Kim, AW and Rieder, AD and Cooper-Vince, CE and Kakuhikire, B and Baguma, C and Satinsky, EN and Perkins, JM and Kiconco, A and Namara,
EB and Rasmussen, JD and Ashaba, S and Bangsberg, DR and Tsai, AC and Puffer, ES},
Title = {Maternal adverse childhood experiences, child mental health,
and the mediating effect of maternal depression: A
cross-sectional, population-based study in rural,
southwestern Uganda.},
Journal = {American journal of biological anthropology},
Volume = {182},
Number = {1},
Pages = {19-31},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1002/ajpa.24758},
Abstract = {<h4>Objectives</h4>This study aimed to examine the
intergenerational effects of maternal adverse childhood
experiences (ACEs) and child mental health outcomes in rural
Uganda, as well as the potentially mediating role of
maternal depression in this pathway. Additionally, we sought
to test the extent to which maternal social group membership
attenuated the mediating effect of maternal depression on
child mental health.<h4>Methods</h4>Data come from a
population-based cohort of families living in the Nyakabare
Parish, a rural district in southwestern Uganda. Between
2016 and 2018, mothers completed surveys about childhood
adversity, depressive symptoms, social group membership, and
their children's mental health. Survey data were analyzed
using causal mediation and moderated-mediation
analysis.<h4>Results</h4>Among 218 mother-child pairs, 61
mothers (28%) and 47 children (22%) showed symptoms meeting
cutoffs for clinically significant psychological distress.
In multivariable linear regression models, maternal ACEs had
a statistically significant association with severity of
child conduct problems, peer problems, and total child
difficulty scores. Maternal depression mediated the
relationship between maternal ACEs and conduct problems,
peer problems, and total difficulty, but this mediating
effect was not moderated by maternal group
membership.<h4>Conclusions</h4>Maternal depression may act
as a potential mechanism linking maternal childhood
adversity with poor child mental health in the next
generation. Within a context of elevated rates of
psychiatric morbidity, high prevalence of childhood
adversity, and limited healthcare and economic
infrastructures across Uganda, these results emphasize the
prioritization of social services and mental health
resources for rural Ugandan families.},
Doi = {10.1002/ajpa.24758},
Key = {fds373399}
}
@article{fds373400,
Author = {Giusto, A and Vander Missen and MR and Kosgei, G and Njiriri, F and Puffer,
E and Kamaru Kwobah and E and Barasa, J and Turissini, M and Rasmussen, J and Ott, M and Binayo, J and Rono, W and Jaguga, F},
Title = {Peer-delivered Problem-solving Therapy for Adolescent Mental
Health in Kenya: Adaptation for Context and Training of
Peer-counselors.},
Journal = {Research on child and adolescent psychopathology},
Volume = {51},
Number = {9},
Pages = {1243-1256},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1007/s10802-023-01075-8},
Abstract = {Peer-delivered interventions for adolescent mental health
can help address poor access to mental health interventions.
Questions remain about how interventions can be adapted for
peer delivery and whether peers can be trained. In this
study, we adapted problem solving therapy (PST) for
peer-delivery with adolescents in Kenya and explored whether
peer counselors can be trained in PST. We adapted treatment
prior to and during training using the Cultural Adaptation
and Contextualization for Implementation framework. Nine
peer counselors (Ages 20-24) were selected and trained over
10 days. Peer competencies and knowledge were measured
pre-post using a written exam, a written case study, and
role plays rated using a standardized competency measure. We
chose a version of PST used in India with secondary school
adolescents originally delivered by teachers. All materials
were translated into Kiswahili. Language and format were
adapted to Kenyan adolescents as well as for delivery by
peers with a focus on understandability and relevance (e.g.,
noting shared experience). Metaphors, examples, and visual
materials were adapted for the context to reflect the
culture and vernacular of Kenyan youth. Peer counselors were
able to be trained in PST. Pre-post competencies and
understanding of content showed improvements with peers
minimally meeting patient needs (pre) on average to
moderate/fully meeting patient needs (post). Post-training
written exam score showed an average 90% correct. There is
an adapted version of PST for Kenyan adolescents and peer
delivery. Peer counselors can be trained to deliver a
5-session PST in a community context.},
Doi = {10.1007/s10802-023-01075-8},
Key = {fds373400}
}
@article{fds373401,
Author = {Perkins, JM and Kakuhikire, B and Baguma, C and Evans, CQ and Rasmussen,
JD and Satinsky, EN and Kyokunda, V and Juliet, M and Ninsiima, I and Bangsberg, DR and Tsai, AC},
Title = {Cigarette smoking and misperceived norms among adults in
rural Uganda: a population-based study.},
Journal = {Tobacco control},
Volume = {32},
Number = {5},
Pages = {652-656},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1136/tobaccocontrol-2021-056470},
Abstract = {<h4>Background</h4>Little is known about perceived norms
about cigarette smoking in Uganda or the extent to which
perceptions drive personal cigarette smoking
behaviour.<h4>Methods</h4>We conducted a cross-sectional
study in 2016-2018 that targeted all adults who resided
within eight villages in Rwampara District, southwestern
Uganda. Personal cigarette smoking frequency was elicited by
self-report. We also asked participants what they believed
to be the cigarette smoking frequency of most other adult
men and women in their villages (i.e., perceived norms).
Frequent cigarette smoking was defined as 4+ times/week. We
compared perceived norms to cigarette smoking frequency
reports aggregated at the village level. We used
multivariable Poisson regression to estimate the association
between perceived norms and personal cigarette smoking
behaviour.<h4>Results</h4>Among 1626 participants (91%
response rate), 92 of 719 men (13%) and 6 of 907 women
(0.7%) reported frequent smoking. However, 1030 (63%)
incorrectly believed most men in their villages smoked
cigarettes frequently. Additionally, 116 (7%) incorrectly
believed that most women in their villages smoked cigarettes
frequently. These misperceptions were pervasive across
social strata. Men who misperceived frequent cigarette
smoking as the norm among other men in their villages were
more likely to smoke frequently themselves (adjusted
relative risk=1.49; 95% CI, 1.13 to 1.97).<h4>Conclusions</h4>Most
adults overestimated cigarette smoking frequency among
village peers. Men who incorrectly believed that frequent
smoking was the norm were more likely to engage in frequent
smoking themselves. Applying a 'social norms approach'
intervention by promoting existing healthy norms may prevent
smoking initiation or motivate reductions in smoking among
men in rural Uganda.},
Doi = {10.1136/tobaccocontrol-2021-056470},
Key = {fds373401}
}
@article{fds373403,
Author = {Satinsky, EN and Kakuhikire, B and Baguma, C and Cooper-Vince, CE and Rasmussen, JD and Ashaba, S and Perkins, JM and Ahereza, P and Ayebare,
P and Kim, AW and Puffer, ES and Tsai, AC},
Title = {Caregiver preferences for physically harsh discipline of
children in rural Uganda},
Journal = {Journal of Family Violence},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1007/s10896-023-00536-4},
Abstract = {Purpose: Physically harsh discipline is associated with poor
developmental outcomes among children. These practices are
more prevalent in areas experiencing poverty and resource
scarcity, including in low- and middle-income countries.
Designed to limit social desirability bias, this
cross-sectional study in rural Uganda estimated caregiver
preferences for physically harsh discipline; differences by
caregiver sex, child sex, and setting; and associations with
indicators of household economic stress and insecurity.
Method: Three-hundred-fifty adult caregivers were shown six
hypothetical pictographic scenarios depicting children
whining, spilling a drink, and kicking a caregiver. Girls
and boys were depicted engaging in each of the three
behaviors. Approximately half of the participants were shown
scenes from a market setting and half were shown scenes from
a household setting. For each scenario, caregivers reported
the discipline strategy they would use (time out, beating,
discussing, yelling, ignoring, slapping). Results: Two
thirds of the participants selected a physically harsh
discipline strategy (beating, slapping) at least once. Women
selected more physically harsh discipline strategies than
men (b = 0.40; 95% confidence interval [CI], 0.26 to 0.54).
Participants shown scenes from the market selected fewer
physically harsh discipline strategies than participants
shown scenes from the household (b = -0.51; 95% CI, -0.69 to
-0.33). Finally, caregivers selected more physically harsh
discipline strategies in response to boys than girls.
Indicators of economic insecurity were inconsistently
associated with preferences for physically harsh discipline.
Conclusions: The high prevalence of physically harsh
discipline preferences warrant interventions aimed at
reframing caregivers’ approaches to discipline.},
Doi = {10.1007/s10896-023-00536-4},
Key = {fds373403}
}
%% Rendina, Danielle
@article{fds371131,
Author = {Amaral, WZ and Lubach, GR and Rendina, DN and Phillips, GJ and Lyte, M and Coe, CL},
Title = {Significant Microbial Changes Are Evident in the
Reproductive Tract of Pregnant Rhesus Monkeys at
Mid-Gestation but Their Gut Microbiome Does Not Shift until
Late Gestation.},
Journal = {Microorganisms},
Volume = {11},
Number = {6},
Pages = {1481},
Publisher = {MDPI AG},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.3390/microorganisms11061481},
Abstract = {Vaginal and rectal specimens were obtained from cycling,
pregnant, and nursing rhesus monkeys to assess
pregnancy-related changes in the commensal bacteria in their
reproductive and intestinal tracts. Using 16S rRNA gene
amplicon sequencing, significant differences were found only
in the vagina at mid-gestation, not in the hindgut. To
verify the apparent stability in gut bacterial composition
at mid-gestation, the experiment was repeated with
additional monkeys, and similar results were found with both
16S rRNA gene amplicon and metagenomic sequencing. A
follow-up study investigated if bacterial changes in the
hindgut might occur later in pregnancy. Gravid females were
assessed closer to term and compared to nonpregnant females.
By late pregnancy, significant differences in bacterial
composition, including an increased abundance of 4 species
of <i>Lactobacillus</i> and <i>Bifidobacterium
adolescentis</i>, were detected, but without a shift in the
overall community structure. Progesterone levels were
assessed as a possible hormone mediator of bacterial change.
The relative abundance of only some taxa (e.g.,
<i>Bifidobacteriaceae</i>) were specifically associated with
progesterone. In summary, pregnancy changes the microbial
profiles in monkeys, but the bacterial diversity in their
lower reproductive tract is different from women, and the
composition of their intestinal symbionts remains stable
until late gestation when several Firmicutes become more
prominent.},
Doi = {10.3390/microorganisms11061481},
Key = {fds371131}
}
@article{fds370894,
Author = {Smith, CJ and Rendina, DN and Kingsbury, MA and Malacon, KE and Nguyen,
DM and Tran, JJ and Devlin, BA and Raju, RM and Clark, MJ and Burgett, L and Zhang, JH and Cetinbas, M and Sadreyev, RI and Chen, K and Iyer, MS and Bilbo, SD},
Title = {Microbial modulation via cross-fostering prevents the
effects of pervasive environmental stressors on microglia
and social behavior, but not the dopamine
system.},
Journal = {Molecular Psychiatry},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1038/s41380-023-02108-w},
Abstract = {Environmental toxicant exposure, including air pollution, is
increasing worldwide. However, toxicant exposures are not
equitably distributed. Rather, low-income and minority
communities bear the greatest burden, along with higher
levels of psychosocial stress. Both air pollution and
maternal stress during pregnancy have been linked to
neurodevelopmental disorders such as autism, but biological
mechanisms and targets for therapeutic intervention remain
poorly understood. We demonstrate that combined prenatal
exposure to air pollution (diesel exhaust particles, DEP)
and maternal stress (MS) in mice induces social behavior
deficits only in male offspring, in line with the male bias
in autism. These behavioral deficits are accompanied by
changes in microglial morphology and gene expression as well
as decreased dopamine receptor expression and dopaminergic
fiber input in the nucleus accumbens (NAc). Importantly, the
gut-brain axis has been implicated in ASD, and both
microglia and the dopamine system are sensitive to the
composition of the gut microbiome. In line with this, we
find that the composition of the gut microbiome and the
structure of the intestinal epithelium are significantly
shifted in DEP/MS-exposed males. Excitingly, both the
DEP/MS-induced social deficits and microglial alterations in
males are prevented by shifting the gut microbiome at birth
via a cross-fostering procedure. However, while social
deficits in DEP/MS males can be reversed by chemogenetic
activation of dopamine neurons in the ventral tegmental
area, modulation of the gut microbiome does not impact
dopamine endpoints. These findings demonstrate male-specific
changes in the gut-brain axis following DEP/MS and suggest
that the gut microbiome is an important modulator of both
social behavior and microglia.},
Doi = {10.1038/s41380-023-02108-w},
Key = {fds370894}
}
%% Reuben, Aaron
@article{fds376690,
Author = {Reuben, A and Richmond-Rakerd, LS and Milne, B and Shah, D and Pearson,
A and Hogan, S and Ireland, D and Keenan, R and Knodt, AR and Melzer, T and Poulton, R and Ramrakha, S and Whitman, ET and Hariri, AR and Moffitt,
TE and Caspi, A},
Title = {Dementia, dementia's risk factors and premorbid brain
structure are concentrated in disadvantaged areas: National
register and birth-cohort geographic analyses.},
Journal = {Alzheimer's & dementia : the journal of the Alzheimer's
Association},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1002/alz.13727},
Abstract = {<h4>Introduction</h4>Dementia risk may be elevated in
socioeconomically disadvantaged neighborhoods. Reasons for
this remain unclear, and this elevation has yet to be shown
at a national population level.<h4>Methods</h4>We tested
whether dementia was more prevalent in disadvantaged
neighborhoods across the New Zealand population (N = 1.41
million analytic sample) over a 20-year observation. We then
tested whether premorbid dementia risk factors and
MRI-measured brain-structure antecedents were more prevalent
among midlife residents of disadvantaged neighborhoods in a
population-representative NZ-birth-cohort (N = 938
analytic sample).<h4>Results</h4>People residing in
disadvantaged neighborhoods were at greater risk of dementia
(HR per-quintile-disadvantage-increase = 1.09, 95%
confidence interval [CI]:1.08-1.10) and, decades before
clinical endpoints typically emerge, evidenced elevated
dementia-risk scores (CAIDE, LIBRA, Lancet, ANU-ADRI,
DunedinARB; β's 0.31-0.39) and displayed
dementia-associated brain structural deficits and cognitive
difficulties/decline.<h4>Discussion</h4>Disadvantaged
neighborhoods have more residents with dementia, and decades
before dementia is diagnosed, residents have more
dementia-risk factors and brain-structure antecedents.
Whether or not neighborhoods causally influence risk, they
may offer scalable opportunities for primary dementia
prevention.},
Doi = {10.1002/alz.13727},
Key = {fds376690}
}
@article{fds372451,
Author = {Hood, CO and Schick, MR and Cusack, SE and Fahey, MC and Giff, ST and Guty,
ET and Hellman, N and Henry, LM and Hinkson, K and Long, EE and McCoy, K and O'Connor, K and Wilborn, AP and Reuben, A and Sackey, ET and Tilstra-Ferrell, EL and Walters, KJ and Witcraft,
SM},
Title = {Short-changing the future: The systemic gap between
psychology internship stipends and living
wages.},
Journal = {Training and education in professional psychology},
Volume = {18},
Number = {1},
Pages = {49-58},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1037/tep0000449},
Abstract = {<h4>Introduction</h4>Providing doctoral internship stipends
below living wages may harm interns, the clinical services
they provide, and the field of health service psychology as
a whole. This study evaluated the extent to which doctoral
psychology internship stipends from the 2021-2022 training
year for APA-accredited, APPIC-member programs in the US are
consistent with living wages in the geographic region where
sites are located.<h4>Methods</h4>We obtained data
reflecting internship sites' geographic location and
stipends for the 2021-2022 academic year. Using the
Massachusetts Institute of Technology Living Wage
Calculator, we computed a living wage for the county in
which each internship site is located. Descriptive
statistics, discrepancies, ratios, and correlations were
calculated to reflect the associations between internship
sites' stipends and their local living wages.<h4>Results</h4>The
average internship stipend was $31,783, which was lower than
the average living wage by $2,091. Stipends ranged widely,
from a low of $15,000 to a high of $94,595-reflecting a
six-fold difference in wages. Although internship sites in
higher cost of living areas paid higher stipends, over
two-thirds (67.0%) of sites did not pay a stipend that
equaled or exceeded a living wage. Ninety-eight sites
(15.3%) had deficits of over $10,000 when comparing their
stipends to local living wages, with $33,240 as the highest
deficit.<h4>Discussion</h4>Eliminating obstacles to
educating health service psychologists by decreasing the
financial burden of training will likely have subsequent
critical benefits towards bridging the workforce gap between
mental healthcare service needs and available providers,
ultimately leading to improved population
health.},
Doi = {10.1037/tep0000449},
Key = {fds372451}
}
@article{fds375340,
Author = {Reuben, A and Ward, R and Rothbaum, AO and Cornelison, VL and Huffman,
S and McTeague, LM and Schmidt, MG and Specht, AJ and Kilpatrick,
DG},
Title = {Who tests for lead and why? A 10-year analysis of blood lead
screening, follow-up and CNS outcomes in a statewide US
healthcare system.},
Journal = {Occupational and environmental medicine},
Volume = {81},
Number = {2},
Pages = {101-108},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1136/oemed-2023-109210},
Abstract = {<h4>Objectives</h4>This study aims to determine (1) which
providers in US healthcare systems order lead tests, why and
at what frequency and (2) whether current patient population
lead levels are predictive of clinical outcomes.<h4>Methods</h4>Retrospective
medical record study of all blood lead tests in the Medical
University of South Carolina healthcare system 2012-2016 and
consequent evidence of central nervous system (CNS)-related
disease across a potential 10-year window
(2012-2022).<h4>Results</h4>Across 4 years, 9726 lead tests
resulted for 7181 patients (49.0% female; 0-94 years),
representing 0.2% of the hospital population. Most tests
were for young (76.6%≤age 3) and non-Hispanic black
(47.2%) and Hispanic (26.7%) patients. A wide variety of
providers ordered tests; however, most were ordered by
paediatrics, psychiatry, internal medicine and neurology.
Lead levels ranged from ≤2.0 µg/dL (80.8%) to
≥10 µg/dL (0.8%; max 36 µg/dL). 201 children (3.1%)
had initial lead levels over the reference value for case
management at the time (5.0 µg/dL). Many high level
children did not receive follow-up testing in the system
(36.3%) and those that did often failed to see levels fall
below 5.0 µg/dL (80.1%). Non-Hispanic black and Hispanic
patients were more likely to see lead levels stay high or go
up over time. Over follow-up, children with high lead levels
were more likely to receive new attention-deficit/hyperactivity
disorder and conduct disorder diagnoses and new psychiatric
medications. No significant associations were found between
lead test results and new CNS diagnoses or medications among
adults.<h4>Conclusions</h4>Hospital lead testing covers a
small portion of patients but includes a wide range of ages,
presentations and provider specialities. Lack of lead
decline among many paediatric patients suggests there is
room to improve provider guidance around when to test and
follow-up.},
Doi = {10.1136/oemed-2023-109210},
Key = {fds375340}
}
@article{fds376091,
Author = {Dong, J and Browning, MHEM and Reuben, A and McAnirlin, O and Yuan, S and Stephens, C and Maisonet, M and Zhang, K and Hart, JE and James, P and Yeager, R},
Title = {The paradox of high greenness and poor health in rural
Central Appalachia.},
Journal = {Environmental research},
Volume = {248},
Pages = {118400},
Year = {2024},
Month = {February},
url = {http://dx.doi.org/10.1016/j.envres.2024.118400},
Abstract = {While many studies have found positive correlations between
greenness and human health, rural Central Appalachia is an
exception. The region has high greenness levels but poor
health. The purpose of this commentary is to provide a
possible explanation for this paradox: three sets of factors
overwhelming or attenuating the health benefits of
greenness. These include environmental (e.g., steep
typography and limited access to green space used for
outdoor recreation), social (e.g., chronic poverty,
declining coal industry, and limited access to healthcare),
and psychological and behavioral factors (e.g., perceptions
about health behaviors, healthcare, and greenness). The
influence of these factors on the expected health benefits
of greenness should be considered as working hypotheses for
future research. Policymakers and public health officials
need to ensure that greenness-based interventions account
for contextual factors and other determinants of health to
ensure these interventions have the expected health
benefits.},
Doi = {10.1016/j.envres.2024.118400},
Key = {fds376091}
}
@article{fds373398,
Author = {Browning, MHEM and Locke, DH and Konijnendijk, C and Labib, SM and Rigolon, A and Yeager, R and Bardhan, M and Berland, A and Dadvand, P and Helbich, M and Li, F and Li, H and James, P and Klompmaker, J and Reuben,
A and Roman, LA and Tsai, W-L and Patwary, M and O'Neil-Dunne, J and Ossola, A and Wang, R and Yang, B and Yi, L and Zhang, J and Nieuwenhuijsen, M},
Title = {Measuring the 3-30-300 rule to help cities meet nature
access thresholds.},
Journal = {The Science of the total environment},
Volume = {907},
Pages = {167739},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.scitotenv.2023.167739},
Abstract = {The 3-30-300 rule offers benchmarks for cities to promote
equitable nature access. It dictates that individuals should
see three trees from their dwelling, have 30 % tree canopy
in their neighborhood, and live within 300 m of a
high-quality green space. Implementing this demands thorough
measurement, monitoring, and evaluation methods, yet little
guidance is currently available to pursue these actions. To
overcome this gap, we employed an expert-based consensus
approach to review the available ways to measure 3-30-300 as
well as each measure's strengths and weaknesses. We
described seven relevant data and processes: vegetation
indices, street level analyses, tree inventories,
questionnaires, window view analyses, land cover maps, and
green space maps. Based on the reviewed strengths and
weaknesses of each measure, we presented a suitability
matrix to link recommended measures with each component of
the rule. These recommendations included surveys and
window-view analyses for the '3 component', high-resolution
land cover maps for the '30 component', and green space maps
with network analyses for the '300 component'. These
methods, responsive to local situations and resources, not
only implement the 3-30-300 rule but foster broader dialogue
on local desires and requirements. Consequently, these
techniques can guide strategic investments in urban greening
for health, equity, biodiversity, and climate
adaptation.},
Doi = {10.1016/j.scitotenv.2023.167739},
Key = {fds373398}
}
@article{fds375278,
Author = {Browning, MHEM and Hanley, JR and Bailey, CR and Beatley, T and Gailey,
S and Hipp, JA and Larson, LR and James, P and Jennings, V and Jimenez, MP and Kahn, PH and Li, D and Reuben, A and Rigolon, A and Sachs, NA and Pearson,
AL and Minson, CT},
Title = {Quantifying Nature: Introducing NatureScoreTM and
NatureDoseTM as Health Analysis and Promotion
Tools.},
Journal = {American journal of health promotion : AJHP},
Volume = {38},
Number = {1},
Pages = {126-134},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1177/08901171231210806b},
Doi = {10.1177/08901171231210806b},
Key = {fds375278}
}
@article{fds374399,
Author = {Onookome-Okome, T and Hsu, A and Kilpatrick, DG and Moreland, A and Reuben, A},
Title = {Association of Public Works Disasters with Substance Use
Difficulties: Evidence from Flint, Michigan, Five Years
after the Water Crisis Onset.},
Journal = {International journal of environmental research and public
health},
Volume = {20},
Number = {23},
Pages = {7090},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.3390/ijerph20237090},
Abstract = {Public works environmental disasters such as the Flint water
crisis typically occur in disenfranchised communities with
municipal disinvestment and co-occurring risks for poor
mental health (poverty, social disconnection). We evaluated
the long-term interplay of the crisis and these factors with
substance use difficulties five years after the crisis
onset. A household probability sample of 1970 adults living
in Flint during the crisis was surveyed about their crisis
experiences, use of substances since the crisis, and
risk/resilience factors, including prior potentially
traumatic event exposure and current social support.
Analyses were weighted to produce population-representative
estimates. Of the survey respondents, 17.0% reported that
substance use since the crisis contributed to problems with
their home, work, or social lives, including 11.2% who used
despite a doctor's warnings that it would harm their health,
12.3% who used while working or going to school, and 10.7%
who experienced blackouts after heavy use. A total of 61.6%
of respondents reported using alcohol since the crisis,
32.4% using cannabis, and 5.2% using heroin,
methamphetamine, or non-prescribed prescription opioids.
Respondents who believed that exposure to contaminated water
harmed their physical health were more likely to use
substances to the detriment of their daily lives (RR = 1.32,
95%CI: 1.03-1.70), as were respondents with prior
potentially traumatic exposure (RR = 2.99, 95%CI:
1.90-4.71), low social support (RR = 1.94, 95%CI:
1.41-2.66), and PTSD and depression (RR's of 1.78 and 1.49,
respectively, <i>p</i>-values < 0.01). Public works
disasters occurring in disenfranchised communities may have
complex, long-term associations with substance use
difficulties.},
Doi = {10.3390/ijerph20237090},
Key = {fds374399}
}
@article{fds372266,
Author = {Bardhan, M and Zhang, K and Browning, MHEM and Dong, J and Liu, T and Bailey, C and McAnirlin, O and Hanley, J and Minson, CT and Mutel, RL and Ranganathan, S and Reuben, A},
Title = {Time in nature is associated with higher levels of positive
mood: Evidence from the 2023 NatureDose™ student
survey},
Journal = {Journal of Environmental Psychology},
Volume = {90},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1016/j.jenvp.2023.102083},
Abstract = {Growing evidence shows that exposure to nature can improve
mood. However, this evidence is mostly based on short-term
or subjectively reported exposures. Machine learning and GPS
mobile device tracking offer fine-grained assessments of
minute-by-minute nature exposure over long periods. Few
studies on nature exposure and mood have leveraged these
technologies. We conducted one of the first longer-term
investigations of daily nature exposure and mood with a
mobile app as part of the NatureDose™ Student Study
(NDSS). The NatureDose™ app uses GPS and a phone's sensors
to evaluate whether a person is inside or outside and checks
levels of nature surrounding the person with the
NatureScore™ measure. This measure is based on more than
30 remotely sensed datasets, geo-located health records, and
machine learning models. College students' nature exposure
(N = 154 initial recruitment) was monitored for eight weeks
(March 7 to May 1, 2022). Their mood states were calculated
weekly using the Positive and Negative Affect Schedule
(PANAS). Both exposure and outcome measures were continuous
values. After three weeks, randomly selected groups of
students were asked to either maintain or increase their
nature exposures. However, students asked to increase their
nature exposures maintained them. Therefore, evaluating
cause-and-effect relationships through an experimental
design was not possible. Instead, we evaluated observational
associations between average nature exposure and mood levels
across the study period using mixed-effect linear regression
models adjusting for gender and allergies. Among the 97
participants with available data, we observed a positive
association between nature exposure and positive mood (β =
0.10 [0.04–0.17], p = .003) but not negative mood (β =
0.01 [-0.07-0.09], p = .76). These findings were supported
by sensitivity analyses with ANOVA models between tertiles
on average NatureDose™ levels. We also found that the
average nature exposure was 71 min per day, most of which
(66%) was earned within 10 km of the center of the
university campus. The study supports the utility of using
NatureDose™ as an app-based tracking tool for objective
nature exposure measurement. The study also reinforces
previous findings on the associations between nature
exposure and positive mood states. Greening university
campuses and surrounding locations where college students
live and spend leisure time could support college students'
mental health.},
Doi = {10.1016/j.jenvp.2023.102083},
Key = {fds372266}
}
@article{fds369954,
Author = {Newbury, JB and Arseneault, L and Moffitt, TE and Odgers, CL and Howe,
LD and Bakolis, I and Reuben, A and Danese, A and Sugden, K and Williams,
B and Rasmussen, LJH and Trotta, A and Ambler, AP and Fisher,
HL},
Title = {Socioenvironmental Adversity and Adolescent Psychotic
Experiences: Exploring Potential Mechanisms in a UK
Longitudinal Cohort.},
Journal = {Schizophrenia bulletin},
Volume = {49},
Number = {4},
Pages = {1042-1054},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1093/schbul/sbad017},
Abstract = {<h4>Background and hypothesis</h4>Children exposed to
socioenvironmental adversities (eg, urbanicity, pollution,
neighborhood deprivation, crime, and family disadvantage)
are more likely to subsequently develop subclinical
psychotic experiences during adolescence (eg, hearing
voices, paranoia). However, the pathways through which this
occurs have not been previously investigated. We
hypothesized that cognitive ability and inflammation would
partly explain this association.<h4>Study design</h4>Data
were utilized from the Environmental-Risk Longitudinal Twin
Study, a cohort of 2232 children born in 1994-1995 in
England and Wales and followed to age 18. Socioenvironmental
adversities were measured from birth to age 10 and
classified into physical risk (defined by high urbanicity
and air pollution) and socioeconomic risk (defined by high
neighborhood deprivation, neighborhood disorder, and family
disadvantage). Cognitive abilities (overall, crystallized,
fluid, and working memory) were assessed at age 12; and
inflammatory markers (C-reactive protein, interleukin-6,
soluble urokinase plasminogen activator receptor) were
measured at age 18 from blood samples. Participants were
interviewed at age 18 regarding psychotic
experiences.<h4>Study results</h4>Higher physical risk and
socioeconomic risk were associated with increased odds of
psychotic experiences in adolescence. The largest mediation
pathways were from socioeconomic risk via overall cognitive
ability and crystallized ability, which accounted for ~11%
and ~19% of the association with psychotic experiences,
respectively. No statistically significant pathways were
found via inflammatory markers in exploratory (partially
cross-sectional) analyses.<h4>Conclusions</h4>Cognitive
ability, especially crystallized ability, may partly explain
the association between childhood socioenvironmental
adversity and adolescent psychotic experiences.
Interventions to support cognitive development among
children living in disadvantaged settings could buffer them
against developing subclinical psychotic
phenomena.},
Doi = {10.1093/schbul/sbad017},
Key = {fds369954}
}
@article{fds370889,
Author = {Pearson, AL and Brown, CD and Reuben, A and Nicholls, N and Pfeiffer,
KA and Clevenger, KA},
Title = {Elementary Classroom Views of Nature Are Associated with
Lower Child Externalizing Behavior Problems.},
Journal = {International journal of environmental research and public
health},
Volume = {20},
Number = {9},
Pages = {5653},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.3390/ijerph20095653},
Abstract = {Exposure to nature views has been associated with diverse
mental health and cognitive capacity benefits. Yet, much of
this evidence was derived in adult samples and typically
only involves residential views of nature. Findings from
studies with children suggest that when more greenness is
available at home or school, children have higher academic
performance and have expedited attention restoration,
although most studies utilize coarse or subjective
assessments of exposure to nature and largely neglect
investigation among young children. Here, we investigated
associations between objectively measured visible nature at
school and children's behavior problems (attention and
externalizing behaviors using the Brief Problem Monitor
Parent Form) in a sample of 86 children aged seven to nine
years old from 15 classrooms across three schools. Images of
classroom windows were used to quantify overall nature views
and views of specific nature types (sky, grass, tree,
shrub). We fitted separate Tobit regression models to test
associations between classroom nature views and attention
and externalizing behaviors, accounting for age, sex,
race/ethnicity, residential deprivation score, and
residential nature views (using Google Street View imagery).
We found that higher levels of visible nature from classroom
windows were associated with lower externalizing behavior
problem scores, after confounder adjustment. This
relationship was consistent for visible trees, but not other
nature types. No significant associations were detected for
attention problems. This initial study suggests that
classroom-based exposure to visible nature, particularly
trees, could benefit children's mental health, with
implications for landscape and school design.},
Doi = {10.3390/ijerph20095653},
Key = {fds370889}
}
@misc{fds376691,
Author = {Manczak, EM and Reuben, A and Solomon, GM},
Title = {Environmental exposures and mental health},
Volume = {4},
Pages = {V4-191-V4-200},
Booktitle = {Encyclopedia of Toxicology, Fourth Edition: Volume
1-9},
Year = {2023},
Month = {January},
ISBN = {9780128243152},
url = {http://dx.doi.org/10.1016/B978-0-12-824315-2.00427-9},
Abstract = {Consideration of psychological health and mental disorders
is necessary for understanding the breadth of effects that
environmental exposures can have on human health. Some
common toxicants disrupt biological processes in ways that
can contribute to psychopathology. While direct biological
exposures are one pathway for these effects, there is
evidence that the threat of exposure may also contribute to
negative psychological outcomes. Environmental disasters and
climate change are clearly associated with psychological
effects, and disasters increase the prevalence of certain
psychiatric disorders. In contrast, exposure to positive
environments can promote adaptive mental health and is
associated with reduced risk of psychopathology.},
Doi = {10.1016/B978-0-12-824315-2.00427-9},
Key = {fds376691}
}
%% Rosenthal, Mark Z.
@article{fds376146,
Author = {Neacsiu, AD and Beynel, L and Gerlus, N and LaBar, KS and Bukhari-Parlakturk, N and Rosenthal, MZ},
Title = {An experimental examination of neurostimulation and
cognitive restructuring as potential components for
Misophonia interventions.},
Journal = {J Affect Disord},
Volume = {350},
Pages = {274-285},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1016/j.jad.2024.01.120},
Abstract = {Misophonia is a disorder of decreased tolerance to certain
aversive, repetitive common sounds, or to stimuli associated
with these sounds. Two matched groups of adults (29
participants with misophonia and 30 clinical controls with
high emotion dysregulation) received inhibitory
neurostimulation (1 Hz) over a personalized medial
prefrontal cortex (mPFC) target functionally connected to
the left insula; excitatory neurostimulation (10 Hz) over a
personalized dorsolateral PFC (dlPFC) target; and sham
stimulation over either target. Stimulations were applied
while participants were either listening or cognitively
downregulating emotions associated with personalized
aversive, misophonic, or neutral sounds. Subjective units of
distress (SUDS) and psychophysiological measurements (e.g.,
skin conductance response [SCR] and level [SCL]) were
collected. Compared to controls, participants with
misophonia reported higher distress (∆SUDS = 1.91-1.93,
ps < 0.001) when listening to and when downregulating
misophonic distress. Both types of neurostimulation reduced
distress significantly more than sham, with excitatory rTMS
providing the most benefit (Cohen's dSUDS = 0.53;
dSCL = 0.14). Excitatory rTMS also enhanced the regulation
of emotions associated with misophonic sounds in both groups
when measured by SUDS (dcontrol = 1.28;
dMisophonia = 0.94), and in the misophonia group alone
when measured with SCL (d = 0.20). Both types of
neurostimulation were well tolerated. Engaging in cognitive
restructuring enhanced with high-frequency neurostimulation
led to the lowest misophonic distress, highlighting the best
path forward for misophonia interventions.},
Doi = {10.1016/j.jad.2024.01.120},
Key = {fds376146}
}
@article{fds376147,
Author = {Guetta, RE and Siepsiak, M and Shan, Y and Frazer-Abel, E and Rosenthal,
MZ},
Title = {Misophonia is related to stress but not directly with
traumatic stress.},
Journal = {PLoS One},
Volume = {19},
Number = {2},
Pages = {e0296218},
Year = {2024},
url = {http://dx.doi.org/10.1371/journal.pone.0296218},
Abstract = {The relationship between misophonia, stress, and traumatic
stress has not been well characterized scientifically. This
study aimed to explore the relationships among misophonia,
stress, lifetime traumatic events, and traumatic stress. A
community sample of adults with self-reported misophonia (N
= 143) completed structured diagnostic interviews and
psychometrically validated self-report measures. Significant
positive correlations were observed among perceived stress,
traumatic stress, and misophonia severity. However,
multivariate analyses revealed that perceived stress
significantly predicted misophonia severity, over and above
traumatic stress symptoms. The number of adverse life events
was not associated with misophonia severity. Among symptom
clusters of post-traumatic stress disorder, only
hyperarousal was associated with misophonia severity. These
findings suggest that transdiagnostic processes related to
stress, such as perceived stress and hyperarousal, may be
important phenotypic features and possible treatment targets
for adults with misophonia.},
Doi = {10.1371/journal.pone.0296218},
Key = {fds376147}
}
@article{fds376148,
Author = {Eom, S and Kim, S and Jiang, Y and Chen, RJ and Roghanizad, AR and Rosenthal, MZ and Dunn, J and Gorlatova, M},
Title = {Investigation of Thermal Perception and Emotional Response
in Augmented Reality using Digital Biomarkers: A Pilot
Study},
Journal = {Proceedings - 2023 IEEE Conference on Virtual Reality and 3D
User Interfaces Abstracts and Workshops, VRW
2023},
Pages = {170-173},
Year = {2023},
Month = {January},
ISBN = {9798350348392},
url = {http://dx.doi.org/10.1109/VRW58643.2023.00042},
Abstract = {Dialectical behavior therapy (DBT) is an evidence-based
psychotherapy that helps patients learn skills to regulate
emotions as a central strategy to improve life functioning.
However, DBT skills require a long-term and consistent
commitment, typically to group therapy over the course of
months. Patients who might benefit may find this approach
undesirable; it can be challenging to transfer learning from
therapy sessions to daily life, and there is no way to
personalize skills learning based on individualized needs.
In this paper we propose the use of Augmented Reality (AR)
and digital biomarkers to enhance DBT skill exercises to be
more immersive and personalized by using physiological data
as real-time feedback. To explore the feasibility of
AR-based DBT skill implementation, we developed AR-based DBT
skill exercises that manipulate the user's thermal
perception by visualizing different thermal information in
holograms. We conducted a user study to evaluate the impact
of AR in changing the thermal perception and emotional
states of the user with an analysis of physiological data
collected from wearable devices.},
Doi = {10.1109/VRW58643.2023.00042},
Key = {fds376148}
}
@article{fds376149,
Author = {Rosenthal, MZ and Campbell, J and Altimus, C},
Title = {Editorial: Advances in understanding the nature and features
of misophonia.},
Journal = {Front Neurosci},
Volume = {17},
Pages = {1267682},
Year = {2023},
url = {http://dx.doi.org/10.3389/fnins.2023.1267682},
Doi = {10.3389/fnins.2023.1267682},
Key = {fds376149}
}
@article{fds376150,
Author = {McMahon, K and Cassiello-Robbins, C and Greenleaf, A and Guetta, R and Frazer-Abel, E and Kelley, L and Rosenthal, MZ},
Title = {The unified protocol for transdiagnostic treatment of
emotional disorders for misophonia: a pilot trial exploring
acceptability and efficacy.},
Journal = {Front Psychol},
Volume = {14},
Pages = {1294571},
Year = {2023},
url = {http://dx.doi.org/10.3389/fpsyg.2023.1294571},
Abstract = {INTRODUCTION: Misophonia is a recently defined disorder
characterized by distressing responses to everyday sounds,
such as chewing or sniffling. Individuals with misophonia
experience significant functional impairment but have
limited options for evidenced-based behavioral treatment. To
address this gap in the literature, the current pilot trial
explored the acceptability and efficacy of a transdiagnostic
cognitive-behavioral approach to treating symptoms of
misophonia. METHODS: This trial was conducted in two
studies: In Study 1, the Unified Protocol for
Transdiagnostic Treatment of Emotional Disorders (UP) was
delivered to eight patients in order to receive feedback to
guide revisions to the treatment to suit this population. In
Study 2, ten patients received the revised UP treatment to
explore its acceptability and preliminary efficacy. This
study used a single-case experimental design with multiple
baselines, randomizing patients to either a 2-week baseline
or 4-week baseline prior to the 16 weeks of treatment,
followed by four weeks of follow-up. RESULTS: The findings
from these studies suggested that patients found both the
original and adapted versions of the UP to be acceptable and
taught them skills for how to manage their misophonia
symptoms. Importantly, the findings also suggested that the
UP can help remediate symptoms of misophonia, particularly
the emotional and behavioral responses. DISCUSSION: These
findings provide preliminary evidence that this
transdiagnostic treatment for emotional disorders can
improve symptoms of misophonia in adults.},
Doi = {10.3389/fpsyg.2023.1294571},
Key = {fds376150}
}
%% Rubin, David C.
@article{fds371260,
Author = {Gehrt, TB and Nielsen, NP and Hoyle, RH and Rubin, DC and Berntsen,
D},
Title = {Narrative identity does not predict well-being when
controlling for emotional valence.},
Journal = {Memory (Hove, England)},
Volume = {31},
Number = {8},
Pages = {1051-1061},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1080/09658211.2023.2218632},
Abstract = {Narrative identity refers to a person's internalized and
evolving life story. It is a rapidly growing research field,
motivated by studies showing a unique association with
well-being. Here we show that this association disappears
when controlling for the emotional valence of the stories
told and individuals' general experience of autobiographical
memory. Participants (<i>N </i>= 235) wrote their life
story and completed questionnaires on their general
experience of autobiographical memory and several dimensions
of well-being and affect. Participants' life stories were
coded for standard narrative identity variables, including
agency and communion. When controlling for emotional valence
of the life story, the general experience of
autobiographical memory was a significant predictor of most
well-being measures, whereas agency was a predictor of one
variable only and communion of none. These findings
contradict the claim of an incremental association between
narrative identity and well-being, and have important
theoretical and practical implications for narrative
identity as an outcome measure in interventions.},
Doi = {10.1080/09658211.2023.2218632},
Key = {fds371260}
}
@article{fds372264,
Author = {Rubin, DC and Bell, CF},
Title = {Using shame to extend Martin Conway's self-memory
system.},
Journal = {Memory (Hove, England)},
Pages = {1-12},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1080/09658211.2023.2241673},
Abstract = {We extend Conway's self-memory system by adding theory and
data from shame, an emotion that disrupts the internalised
ideals of society needed for a positive self-concept. The
event that caused 273 undergraduates their greatest amount
of shame was analyzed; 66% were not very negative except for
producing shame. Ratings of post-event effects, including
two measure of self (self-perceived weakness, and centrality
to identity) and four clinical symptoms (intrusions,
avoidance, anxiety, and depression), were attributed
separately to the remembered event, behaviour during the
event, and shame from the event. The effects of shame were
generally as large as the those of the event and larger than
those of the behaviour, demonstrating the importance of
shame's effects. The Tonic Immobility Scale (TIS), which
measures tonic immobility (i.e., freezing), was obtained for
the event that produced the most tonic immobility but that
was not the event that caused the most shame. The post-event
symptoms measured on the event that caused the most shame
and the TIS correlated highly, suggesting that shame and
tonic immobility may belong to a cluster of phylogenetically
conserved submissive defensive mechanisms that could account
for effects currently attributed to goals in self-memory
systems.},
Doi = {10.1080/09658211.2023.2241673},
Key = {fds372264}
}
@article{fds370313,
Author = {Rubin, DC and Bell, CF},
Title = {Tonic immobility (freezing) during sexual and physical
assaults produces stronger memory effects than other
characteristics of the assaults.},
Journal = {Memory (Hove, England)},
Volume = {31},
Number = {5},
Pages = {678-688},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1080/09658211.2023.2188642},
Abstract = {Tonic immobility (TI) is a phylogenetically conserved,
passive, obligatory defense mechanism commonly engaged
during sexual and physical assaults. During TI, people
become immobile while remaining conscious and later
reexperience intrusive memories of both their assault and of
its accompanying immobility. Here we show that this
well-studied biological process has powerful effects on
memory and other processes. Participants had experienced
either a serious sexual (<i>n</i> = 234) or physical
(<i>n</i> = 137) assault. For both the assault and its
accompanying immobility, the standard measure of the
peritraumatic severity of TI correlated between .40 and .65
with post-assault effects on memory, including memory of the
assault and memory of the immobility, the two memory-based
self-concept measures of self-blame and event centrality,
and post-assault anxiety and depression. The correlations
with TI were much higher than other peritraumatic
characteristics commonly used to predict and describe
posttraumatic effects in assaults and other traumas. The
results suggest that TI should be considered for a broader,
more biologically based and ecologically valid understanding
of the effects of trauma on memory and memory-based
reactions.},
Doi = {10.1080/09658211.2023.2188642},
Key = {fds370313}
}
@article{fds370410,
Author = {Allé, MC and Rubin, DC and Berntsen, D},
Title = {Autobiographical memory and the self on the psychosis
continuum: investigating their relationship with positive-
and negative-like symptoms.},
Journal = {Memory (Hove, England)},
Volume = {31},
Number = {4},
Pages = {518-529},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1080/09658211.2023.2173236},
Abstract = {Autobiographical memory is severely impaired in
schizophrenia, but previous work has largely treated both as
unitary concepts. Here, we examined how various dimensions
of autobiographical memory relate to different aspects of
psychosis. Participants were recruited from the general
population (Study 1, N = 264) and a university subject
pool (Study 2, N = 305). We examined different measures
of autobiographical memory and self (i.e., involuntary
memory, autobiographical recollection, self-knowledge and
self-awareness), at the trait level in Study 1 and both
trait and state levels in Study 2, as a function of
positive-and negative-like symptoms of psychosis. Across
both studies, positive and negative dimensions of psychosis
were found to be related to an increase in involuntary
memories (i.e., the spontaneous recall of personal
memories), and to lower self-concept clarity and insight.
Positive and negative dimensions of psychosis correlated
differently with autobiographical recollection
characteristics, measured at both trait (Studies 1 and 2)
and state levels (Study 2). Positive-like symptoms (in
particular hallucination-proneness) showed a stronger and
more consistent pattern of correlations than negative-like
symptoms. These findings call for a dimensional approach to
the relationship between autobiographical memory and
psychosis symptoms in clinical and non-clinical individuals,
to better understand the breakdown of autobiographical
memory in the psychopathology of psychosis.},
Doi = {10.1080/09658211.2023.2173236},
Key = {fds370410}
}
@article{fds371560,
Author = {Berntsen, D and Hoyle, RH and Munkholm Møller and D and Rubin,
DC},
Title = {Digital daydreaming: Introducing the spontaneous smartphone
checking scale},
Journal = {Applied Cognitive Psychology},
Volume = {37},
Number = {1},
Pages = {147-160},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1002/acp.4034},
Abstract = {Smartphones are a ubiquitous part of many people's lives,
but little is known about their impact on everyday thought
processes. Here we introduce the spontaneous smartphone
checking scale (SSCS)—which measures the tendency to
direct attention toward one's smartphone, unpreceded by
external prompts (e.g., notifications, or alerts) and with
no specific conscious goal in mind, as a parallel to
mind-wandering directed toward internal thoughts. The SSCS
showed good psychometric properties and construct validity.
It separated from measures of daydreaming and mind-wandering
by not loading on dimensions related to self-consciousness,
reflection, and rumination, but instead loading highly on a
factor associated with other aspects of digital
communication and concerns about public appearance on social
media. This suggests that spontaneous smartphone checking
serves different mental and social functions than internally
generated spontaneous thought processes. We discuss possible
long-term effects of spontaneous smartphone checking taking
up time for internally generated spontaneous
thoughts.},
Doi = {10.1002/acp.4034},
Key = {fds371560}
}
@article{fds371743,
Author = {Shan, Y and Yan, S and Jia, Y and Hu, Y and Rubin, DC and Berntsen,
D},
Title = {The Properties of Involuntary and Voluntary Autobiographical
Memories in Chinese Patients with Depression and Healthy
Individuals},
Journal = {Cognitive Therapy and Research},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1007/s10608-023-10353-0},
Abstract = {Background: Research on depression has largely focused on
negative intrusive memories with little research on general
involuntary memories as they occur in everyday life. In
addition, all studies have been conducted on Western
participants, and there are no studies on general
involuntary memory in Eastern patients with depression.
Methods: Thirty Chinese patients with depression and 30
healthy controls completed a memory diary in which they
recorded a total of 10 involuntary and 10 voluntary
memories. They were requested to fill out corresponding
questionnaires of involuntary and voluntary memories as
well. Results: Both patients with depression and healthy
controls reported involuntary memories that had a more
negative impact, were more specific, and were associated
with more maladaptive emotion regulation when compared to
voluntary memories. For both retrieval modes, patients with
depression reported more negative and fewer positive
memories, more negative and less positive mood impact, more
avoidance, rumination, worry, negative interpretation, and
less positive interpretation in response to the memories.
Patients with depression rated their memories as more
central, less specific, and rehearsed more frequently.
Negative mood impact and maladaptive emotion regulation
associated with involuntary memories were amplified in
depression. Conclusions: These findings support the view
that general involuntary memories could be a potential
target to promote the treatment for depression.},
Doi = {10.1007/s10608-023-10353-0},
Key = {fds371743}
}
%% Salvador, Cristina E
@article{fds372415,
Author = {Kitayama, S and Salvador, CE},
Title = {Cultural Psychology: Beyond East and West.},
Journal = {Annual review of psychology},
Volume = {75},
Pages = {495-526},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1146/annurev-psych-021723-063333},
Abstract = {Research in cultural psychology over the last three decades
has revealed the profound influence of culture on cognitive,
emotional, and motivational processes shaping individuals
into active agents. This article aims to show cultural
psychology's promise in three key steps. First, we review
four notable cultural dimensions believed to underlie
cultural variations: independent versus interdependent self,
individualism versus collectivism, tightness versus
looseness of social norms, and relational mobility. Second,
we examine how ecology and geography shape human activities
and give rise to organized systems of cultural practices and
meanings, called eco-cultural complexes. In turn, the
eco-cultural complex of each zone is instrumental in shaping
a wide range of psychological processes, revealing a
psychological diversity that extends beyond the scope of the
current East-West literature. Finally, we examine some of
the non-Western cultural zones present today, including
Arab, East Asian, Latin American, and South Asian zones, and
discuss how they may have contributed, to varying degrees,
to the formation of the contemporary Western cultural
zone.},
Doi = {10.1146/annurev-psych-021723-063333},
Key = {fds372415}
}
@article{fds376694,
Author = {Zhou, J and West, TN and Lee, SH and Choi, I and Hitokoto, H and Otake, K and Fredrickson, BL and Salvador, CE},
Title = {Do People From Different Cultures Vary in How Much Positive
Emotions Resonate in Day-to-Day Social Interactions?
Examining the Role of Relational Mobility},
Journal = {Journal of Cross-Cultural Psychology},
Publisher = {SAGE Publications},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1177/00220221241235926},
Abstract = {Positivity resonance, defined as a co-experienced
kind-hearted positive emotion, is commonly observed to
strengthen relationships in the United States. However, it
is unclear whether levels of positivity resonance differ
across cultures. Prior research suggests that in cultures
that are perceived as offering more freedom and choice in
social ties (defined as high relational mobility cultures),
individuals more frequently engage in adaptive strategies to
build relationships. We hypothesized that positivity
resonance, achieved via such adaptive strategies, might be
similarly linked to cultural variation in relational
mobility. Across two studies (N = 5,711) we found supportive
evidence for our prediction that, compared with European
American participants, East Asian participants showed lower
levels of positivity resonance with strong social ties. Such
differences were in part explained by lower levels of
perceived relational mobility among East Asian participants.
Comparable effects were not present for weak social ties.
Implications for theories of culture and emotion are
discussed.},
Doi = {10.1177/00220221241235926},
Key = {fds376694}
}
@article{fds373411,
Author = {Salvador, CE and Idrovo Carlier and S and Ishii, K and Torres Castillo,
C and Nanakdewa, K and San Martin and A and Savani, K and Kitayama,
S},
Title = {Emotionally expressive interdependence in Latin America:
Triangulating through a comparison of three cultural
zones.},
Journal = {Emotion (Washington, D.C.)},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1037/emo0001302},
Abstract = {Evidence suggests that Latin Americans display elevated
levels of emotional expressivity and positivity. Here, we
tested whether Latin Americans possess a unique form of
interdependence called expressive interdependence,
characterized by the open expression of positive emotions
related to social engagement (e.g., feelings of closeness to
others). In Study 1, we compared Latin Americans from Chile
and Mexico with European Americans in the United States, a
group known to be highly independent. Latin Americans
expressed positive socially engaging emotions, particularly
in response to negative events affecting others, whereas
European Americans favored positive socially disengaging
emotions, such as pride, especially in response to
personally favorable circumstances. Study 2 replicated these
findings with another group of Latin Americans from Colombia
and European Americans in the United States. Study 2 also
included Japanese in Japan, who expressed positive emotions
less than Latin and European Americans. However, Japanese
displayed a higher tendency to express negative socially
engaging emotions, such as guilt and shame, compared to both
groups. Our data demonstrate that emotional expression
patterns align with overarching ethos of interdependence in
Latin America and Japan and independence among European
Americans. However, Latin Americans and Japanese exhibited
different styles of interdependence. Latin Americans were
expressive of positive socially engaging emotions, whereas
Japanese were less expressive overall. Moreover, when
Japanese expressed emotions, they emphasized negative
socially engaging emotions. Implications for theories of
culture and emotion are discussed. (PsycInfo Database Record
(c) 2023 APA, all rights reserved).},
Doi = {10.1037/emo0001302},
Key = {fds373411}
}
@article{fds372936,
Author = {Kitayama, S and Salvador, CE and Ackerman, J},
Title = {The germ aversion paradox: When germ aversion predicts
reduced alpha power suppression to norm violations},
Journal = {Current Research in Ecological and Social
Psychology},
Volume = {5},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1016/j.cresp.2023.100150},
Abstract = {Prior work shows that germ-averse individuals are more
norm-abiding than their less germ-averse counterparts in the
absence of any germ threat. However, it is unclear if germ
aversion has similar effects in the presence of a germ
threat. Here, we explored the hypothesis that germ-averse
people would show less sensitivity to social norms because
their perceived success in avoiding germs could make them
feel protected from this threat. As an index of the
sensitivity to norms, we assessed electrocortical reactions
to another person's norm-violating behaviors. 59 young
American adults were either primed with a germ threat or
not. They subsequently saw either norm-violating or normal
behaviors. In the control-priming condition, a reduction in
upper-alpha band power in response to norm-violating (vs.
normal) behaviors (signifiying vigilance to norm violations)
was significantly greater for those high in germ aversion,
thereby conceptually replicating the prior evidence linking
germ aversion to conformity. This effect, however, was
significantly reversed in the threat-priming condition. The
elevated level of neural reactivity to norm violations in
the threat-priming condition, present for those low in germ
aversion, disappeared for those high in germ aversion. Our
findings suggest that although germ aversion predicts
greater norm-abidance in the absence of any germ threat,
this effect paradoxically reverses itself in the presence of
it.},
Doi = {10.1016/j.cresp.2023.100150},
Key = {fds372936}
}
%% Samanez-Larkin, Gregory R.
@article{fds372974,
Author = {Abiodun, SJ and Salerno, JM and McAllister, GA and Samanez-Larkin,
GR and Seaman, KL},
Title = {Adult Age Differences in Evoked Emotional Responses to
Dynamic Facial Expressions.},
Journal = {The journals of gerontology. Series B, Psychological
sciences and social sciences},
Volume = {79},
Number = {1},
Pages = {gbad141},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1093/geronb/gbad141},
Abstract = {<h4>Objectives</h4>Facial expressions are powerful social
signals that motivate feelings and actions in the observer.
Research on face processing has overwhelmingly used static
facial images, which have limited ecological validity.
Previous research on the age-related positivity effect and
age differences in social motivation suggest that older
adults might experience different evoked emotional responses
to facial expressions than younger adults. Here, we
introduce a new method to explore age-related differences in
evoked responses to dynamic facial expressions across
adulthood.<h4>Methods</h4>We used dynamic facial expressions
which varied by expression type (happy, sad, and angry) and
expression magnitude (low, medium, and full) to gather
participant ratings on their evoked emotional response to
these stimuli along the dimensions of valence (positive vs
negative) and arousal.<h4>Results</h4>As predicted, older
adults rated the emotions evoked by positive facial
expressions (happy) more positively than younger adults.
Furthermore, older adults rated the emotion evoked by
negative facial expressions (angry and sad) more negatively
than younger adults. Contrary to our predictions, older
adults did not differ significantly in arousal to negative
expressions compared with younger adults. Across all ages,
individuals rated positive expressions as more arousing than
negative expressions.<h4>Discussion</h4>The findings provide
some evidence that older adults may be more sensitive to
variations in dynamic facial expressions than younger
adults, particularly in terms of their estimates of valence.
These dynamic facial stimuli that vary in magnitude are
promising for future studies of more naturalistic affect
elicitation, studies of social incentive processing, and use
in incentive-driven choice tasks.},
Doi = {10.1093/geronb/gbad141},
Key = {fds372974}
}
@article{fds374402,
Author = {Castrellon, JJ and Zald, DH and Samanez-Larkin, GR and Seaman,
KL},
Title = {Adult age-related differences in susceptibility to social
conformity pressures in self-control over daily
desires.},
Journal = {Psychology and aging},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1037/pag0000790},
Abstract = {Developmental literature suggests that susceptibility to
social conformity pressure peaks in adolescence and
disappears with maturity into early adulthood. Predictions
about these behaviors are less clear for middle-aged and
older adults. On the one hand, while age-related increases
in prioritization of socioemotional goals might predict
greater susceptibility to social conformity pressures, aging
is also associated with enhanced emotion regulation that
could support resistance to conformity pressures. In this
exploratory research study, we used mobile experience
sampling surveys to naturalistically track how 157 healthy
adults between the ages of 18 and 80 practice self-control
over spontaneous desires in daily life. Many of these
desires were experienced in the presence of others enacting
that desire. Results showed that middle-aged and older
adults were better at controlling their desires than younger
adults when desires were experienced in the presence of
others enacting that desire. Consistent with the literature
on improved emotion regulation with age, these results
provide evidence that the ability to resist social
conformity pressure is enhanced across the adult life span.
(PsycInfo Database Record (c) 2023 APA, all rights
reserved).},
Doi = {10.1037/pag0000790},
Key = {fds374402}
}
@article{fds358298,
Author = {Seaman, KL and Juarez, EJ and Troutman, A and Salerno, JM and Samanez-Larkin, SP and Samanez-Larkin, GR},
Title = {Decision Making across Adulthood during Physical
Distancing.},
Journal = {Neuropsychol Dev Cogn B Aging Neuropsychol
Cogn},
Volume = {30},
Number = {1},
Pages = {53-65},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/13825585.2021.1962793},
Abstract = {Covid-19-related social-distancing measures have
dramatically limited physical social contact between
individuals and increased monetary and health concerns for
individuals of all ages. We wondered how these new societal
conditions would impact the choices individuals make about
monetary, health, and social rewards, and if these
unprecedented conditions would have a differential impact on
older individuals. We conducted two online studies to
examine temporal discounting of monetary, health, and social
rewards; stated preferences for monetary, health, and social
rewards; and physical distancing behaviors. Both studies
recruited equal numbers of White/Caucasian, Black/African
American, and Hispanic/Latinx participants. We found that
older adults were more likely to prefer smaller, sooner
social and health-related rewards in decision-making tasks.
These data further support the assertion that older adults
have increased motivation for social and health rewards
compared to younger individuals and that these age
differences in motivation are important to consider when
examining decision-making across the adult life
span.},
Doi = {10.1080/13825585.2021.1962793},
Key = {fds358298}
}
@article{fds369179,
Author = {Sinclair, AH and Taylor, MK and Weitz, JS and Beckett, SJ and Samanez-Larkin, GR},
Title = {Reasons for Receiving or Not Receiving Bivalent COVID-19
Booster Vaccinations Among Adults - United States, November
1-December 10, 2022.},
Journal = {MMWR. Morbidity and mortality weekly report},
Volume = {72},
Number = {3},
Pages = {73-75},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.15585/mmwr.mm7203a5},
Abstract = {Bivalent COVID-19 booster vaccines, developed to protect
against both ancestral and Omicron BA.4/BA.5 variants, are
recommended to increase protection against SARS-CoV-2
infection and severe disease* (1,2). However, relatively few
eligible U.S. adults have received a bivalent booster dose
(3), and reasons for low coverage are unclear. An opt-in
Internet survey of 1,200 COVID-19-vaccinated U.S. adults was
conducted to assess reasons for receiving or not receiving a
bivalent booster dose. Participants could select multiple
reasons from a list of suggested reasons to report why they
had or had not received a bivalent booster dose. The most
common reasons cited for not receiving the bivalent booster
dose were lack of awareness of eligibility for vaccination
(23.2%) or of vaccine availability (19.3%), and perceived
immunity against infection (18.9%). After viewing
information about eligibility and availability, 67.8% of
participants who had not received the bivalent booster dose
indicated that they planned to do so; in a follow-up survey
1 month later, 28.6% of these participants reported having
received the dose. Among those who had planned to receive
the booster dose but had not yet done so, 82.6% still
intended to do so. Participants who had still not received
the booster dose most commonly reported being too busy to
get vaccinated (35.6%). To help increase bivalent booster
dose coverage, health care and public health professionals
should use evidence-based strategies to convey information
about booster vaccination recommendations and waning
immunity (4), while also working to increase convenient
access.},
Doi = {10.15585/mmwr.mm7203a5},
Key = {fds369179}
}
@article{fds370892,
Author = {Green, MA and Crawford, JL and Kuhnen, CM and Samanez-Larkin, GR and Seaman, KL},
Title = {Multivariate associations between dopamine receptor
availability and risky investment decision-making across
adulthood.},
Journal = {Cerebral cortex communications},
Volume = {4},
Number = {2},
Pages = {tgad008},
Publisher = {Oxford University Press (OUP)},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1093/texcom/tgad008},
Abstract = {Enhancing dopamine increases financial risk taking across
adulthood but it is unclear whether baseline individual
differences in dopamine function are related to risky
financial decisions. Here, thirty-five healthy adults
completed an incentive-compatible risky investment decision
task and a PET scan at rest using [11C]FLB457 to assess
dopamine D2-like receptor availability. Participants made
choices between a safe asset (bond) and a risky asset
(stock) with either an expected value less than the bond
("bad stock") or expected value greater than the bond ("good
stock"). Five measures of behavior (choice inflexibility,
risk seeking, suboptimal investment) and beliefs (absolute
error, optimism) were computed and D2-like binding potential
was extracted from four brain regions of interest (midbrain,
amygdala, anterior cingulate, insula). We used canonical
correlation analysis to evaluate multivariate associations
between decision-making and dopamine function controlling
for age. Decomposition of the first dimension
(<i>r</i> = 0.76) revealed that the strongest
associations were between measures of choice inflexibility,
incorrect choice, optimism, amygdala binding potential, and
age. Follow-up univariate analyses revealed that amygdala
binding potential and age were both independently associated
with choice inflexibility. The findings suggest that
individual differences in dopamine function may be
associated with financial risk taking in healthy
adults.},
Doi = {10.1093/texcom/tgad008},
Key = {fds370892}
}
%% Schramm-Sapyta, Nicole L.
@article{fds376751,
Author = {Shevchouk, OT and Dowling, GJ and Schramm-Sapyta,
NL},
Title = {Editorial: New insights on bringing social context into
addiction neuroscience.},
Journal = {Frontiers in behavioral neuroscience},
Volume = {18},
Pages = {1383016},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.3389/fnbeh.2024.1383016},
Doi = {10.3389/fnbeh.2024.1383016},
Key = {fds376751}
}
@article{fds372426,
Author = {Easter, MM and Schramm-Sapyta, NL and Tackett, MA and Larsen, IG and Tang, B and Ralph, MA and Huynh, LN},
Title = {Reliance on Community Emergency Departments by People Ever
Detained in Jail: Retrospective Cross-Sectional
Study.},
Journal = {J Correct Health Care},
Volume = {29},
Number = {4},
Pages = {282-292},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1089/jchc.22.02.0011},
Abstract = {Millions are confined in U.S. jails each year, often with
unmet health and social needs. After release, many will
visit the emergency department (ED). To illuminate their
patterns of ED use, this study linked records from all
individuals detained at a Southern urban jail over a 5-year
period with health records from a large health care system
with three EDs. Over half used the ED at least once, and of
those who received care at the health system, 83% visited
the ED. Jail-involved people made up 4.1% of the health care
system's ED users but 21.3% of its chronic frequent ED
users. Frequent ED use was associated with more frequent
jail bookings and with co-occurring serious mental illness
and substance use disorder. Health systems and jails have a
common interest in addressing the needs of this population.
Individuals with co-occurring disorders should be
prioritized for intervention.},
Doi = {10.1089/jchc.22.02.0011},
Key = {fds372426}
}
@article{fds369378,
Author = {Schramm-Sapyta, NL and Ralph, M and Huynh, L and Tang, B and Tackett, M and Easter, M and Larsen, I},
Title = {Relationships between substance use disorders, 'severe
mental illness' and re-arrest in a county detention
facility: A 4-year follow-up cohort study.},
Journal = {Crim Behav Ment Health},
Volume = {33},
Number = {3},
Pages = {185-195},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1002/cbm.2277},
Abstract = {BACKGROUND: A growing body of literature demonstrates strong
association between poor mental health and criminal
recidivism, but research from county jails is limited. AIMS:
Our aim was to examine the relationship between re-arrest
and severe mental illnesses-schizophrenia, bipolar disorder
and major depressive disorder-together and separately and
with substance use disorders, separately and as comorbid
conditions, in a mid-sized county jail cohort in the
southeastern United States. METHODS: We examined the full
cohort of 8097 individuals who were booked into the County
Detention Facility between 31 January 2014 and 31 January
2015. Their incarceration data were merged with data from
the local health system to investigate the presence of
severe mental illness and substance use disorder diagnoses.
Re-arrest data were tracked for 4 years after the index
arrest. RESULTS: Approximately 60% of the cohort was
re-arrested within 4 years. People with substance use
disorders, with or without severe mental illness, had higher
re-arrest rates than those with severe mental illness alone
or neither diagnosis. Drug-associated arrests did not
explain this finding. CONCLUSIONS: Using detailed mental
illness diagnosis data with a complete cohort of detained
arrestees, we have shown the wide range of need among such
individuals. By demonstrating that drug-associated crimes
per se do not drive repeated arrest, we underscore a need to
examine other factors that promote the cycle of repeated
arrest in this population. Each individual requires
treatment tailored to their personal psychiatric and
criminogenic needs.},
Doi = {10.1002/cbm.2277},
Key = {fds369378}
}
%% Schuette, Stephanie
@article{fds371467,
Author = {Schuette, SA and Andrade, FC and Woodward, JT and Smoski,
MJ},
Title = {Identifying modifiable factors associated with psychological
health in women experiencing infertility.},
Journal = {J Health Psychol},
Volume = {28},
Number = {12},
Pages = {1143-1156},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1177/13591053231185549},
Abstract = {This study assessed the relationship between modifiable
psychological variables and depression, anxiety, and
posttraumatic growth in women experiencing infertility. U.S.
women (N = 457) who identified as experiencing infertility
completed standardized self-report measures of mindfulness,
self-compassion, positive affect, intolerance of
uncertainty, relationship satisfaction, experiential
avoidance, depression, anxiety, and posttraumatic growth.
Clinical and demographic characteristics (age, duration
trying to conceive, miscarriage, and childlessness) did not
predict depression or anxiety. Lower positive affect and
higher experiential avoidance were associated with
depression and anxiety. Lower self-compassion was associated
with depression; higher intolerance of uncertainty was
associated with anxiety. There were indirect effects of
mindfulness on anxiety and depression via these variables.
Future research should explore whether intervening on these
factors reduces depressive and anxiety symptoms. Promoting
mindfulness may have beneficial effects on symptoms via its
downstream effects on multiple coping variables.
Counterintuitively, posttraumatic growth was associated with
higher intolerance of uncertainty and experiential
avoidance.},
Doi = {10.1177/13591053231185549},
Key = {fds371467}
}
%% Seli, Paul
@article{fds374608,
Author = {Landry, AP and Fincher, K and Barr, N and Brosowsky, NP and Protzko, J and Ariely, D and Seli, P},
Title = {Harnessing dehumanization theory, modern media, and an
intervention tournament to reduce support for retributive
war crimes},
Journal = {Journal of Experimental Social Psychology},
Volume = {111},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1016/j.jesp.2023.104567},
Abstract = {We demonstrate how psychological scientists can curate
rich-yet-accessible media to intervene on
conflict-escalating attitudes during the earliest stages of
violent conflicts. Although wartime atrocities all-too-often
ignite destructive cycles of tit-for-tat war crimes,
powerful third parties can de-escalate the bloodshed.
Therefore, following Russia's illegal invasion of Ukraine,
we aimed to reduce Americans' support for committing
retributive war crimes against Russian soldiers. To
intervene during the earliest stages of the invasion, we
drew on theories of dehumanization and “parasocial”
intergroup contact to curate publicly available media
expected to humanize Russian soldiers. We then identified
the most effective materials by simultaneously evaluating
all of them with an intervention tournament. This allowed us
to quickly implement a psychological intervention that
reliably reduced support for war crimes during the first
days of a momentous land war. Our work provides a practical,
result-driven model for developing psychological
interventions with the potential to de-escalate incipient
conflicts.},
Doi = {10.1016/j.jesp.2023.104567},
Key = {fds374608}
}
@article{fds376752,
Author = {Ragnhildstveit, A and Tuteja, N and Seli, P and Smart, L and Uzun, N and Bass, LC and Miranda, AC and Ford, TJ and Neufeld,
SAS},
Title = {Transitions from child and adolescent to adult mental health
services for eating disorders: an in-depth systematic review
and development of a transition framework.},
Journal = {Journal of eating disorders},
Volume = {12},
Number = {1},
Pages = {36},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1186/s40337-024-00984-3},
Abstract = {<h4>Background</h4>Eating disorders (EDs) peak in
mid-to-late adolescence and often persist into adulthood.
Given their early onset and chronicity, many patients
transition from child and adolescent mental health services
(CAMHS) to adult mental health services (AMHS) for ongoing,
speciality ED care. This transition typically occurs at
18 years of age, when important biological, psychosocial,
and vocational changes take place. Thus, smooth and
effective transitions are paramount for ensuring service
continuity, as well as reducing the risk of ED relapse and
premature death. Here, we synthesized evidence on
transitions from CAMHS to AMHS for young people with EDs,
aiming to inform future research, clinical practice, and
healthcare policy.<h4>Methods</h4>A systematic review of the
literature was conducted. This adhered to PRISMA guidelines.
PubMed, Embase, and Scopus electronic databases were queried
from inception to December 3, 2023. Leveraging the PICOS
framework, study eligibility was evaluated in the
qualitative synthesis. Data regarding methodology, analytic
approach, and associated outcomes were then extracted. The
quality of evidence was examined using critical appraisal
tools. Finally, concept mapping was applied to organize
findings into a transition framework.<h4>Results</h4>The
search returned 76 articles. Of these, 14 were included in
the final review. Articles were grouped into 'qualitative'
(n = 10), 'cross-sectional' (n = 2), and
'longitudinal cohort' (n = 2) studies based on
research design. Overall, ED transitions were complex,
multifaceted, and challenging for patients, caregivers, and
providers alike. This resulted from an interplay of
temporal- (e.g., timing of ED onset and transition),
stakeholder- (e.g., patient ambivalence towards recovery)
and systemic- (e.g., differences between services) related
factors. Most studies were of moderate-to-high quality.
Findings informed the development of five
transition strategies designed to facilitate effective
transfers across ED care: Timely talks, Readiness,
Inclusion, Preparation, and Synergy (TRIPS).<h4>Conclusions</h4>Transitions
from CAMHS to AMHS appear problematic for young people with
EDs and other involved stakeholders. The field stands to
benefit from TRIPS, an actionable, evidence-based framework
that aims to alleviate challenges of transitioning and
subsequently improve ED trajectories. As a logical next
step, future work should empirically test the TRIPS
framework, exploring its predictive utility and clinical
value.},
Doi = {10.1186/s40337-024-00984-3},
Key = {fds376752}
}
@article{fds376292,
Author = {Petranker, R and Anderson, T and Fewster, EC and Aberman, Y and Hazan,
M and Gaffrey, M and Seli, P},
Title = {Keeping the promise: a critique of the current state of
microdosing research.},
Journal = {Frontiers in psychiatry},
Volume = {15},
Pages = {1217102},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.3389/fpsyt.2024.1217102},
Abstract = {<h4>Introduction</h4>The practice of taking small,
sub-hallucinogenic doses of psychedelics, known as
microdosing, has exploded in popularity over the last
decade. Users claim benefits ranging from improved mood and
enhanced creativity to an increased sense of meaning and
connectedness in life. While research on microdosing is
still lagging behind the shift in public opinion, several
papers have been published in the last five years which
attempted to assess the effects of microdosing.<h4>Methods</h4>This
review paper aimed to critically analyze the research
practices used in the recent wave of microdosing research:
We reviewed 15 papers published before the closing date of
this review in March 2022.<h4>Results</h4>Our review
concludes that it is premature to draw any conclusions about
the efficacy or safety of microdosing since the research
quality cannot be considered confirmatory.<h4>Discussion</h4>We
propose some potential causes for the current state of the
literature and some suggestions for how these causes may be
ameliorated.},
Doi = {10.3389/fpsyt.2024.1217102},
Key = {fds376292}
}
@article{fds376092,
Author = {Landry, AP and Seli, P},
Title = {A family-resemblances framework for dehumanization
research},
Journal = {Current Research in Ecological and Social
Psychology},
Volume = {6},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.cresp.2024.100185},
Abstract = {Dehumanization has figured prominently in intergroup
discrimination and violence, which has inspired sustained
social-psychological inquiry. Over two decades, researchers
have brought an abundance of theories and methods to bear on
the empirical study of dehumanization. Collectively, this
work has painted an expansive portrait of the many ways we
can overlook or deny the humanity of others. At the same
time, these diverse conceptual and measurement approaches
have progressed in relative isolation, which has created
confusion about what, precisely, is meant by
“dehumanization” and cast uncertainty on fundamental
conclusions drawn from this research. To stimulate
theoretical development and more-productive exchanges across
the field, we offer a Family-Resemblances perspective on
dehumanization research. Specifically, we conceptualize
dehumanization as a multifaceted construct that encompasses
a family of related processes with both overlapping and
unique features. Thus, the diverse theoretical and
methodological approaches to studying dehumanization are
complementary means of capturing a fundamentally
heterogeneous phenomenon. Further, we argue that this
perspective can catalyze a more nuanced and precise
understanding of dehumanization's many facets: by specifying
the different varieties of dehumanization under
investigation, the field can more precisely map them onto
specific targets, causes, consequences, and intervention
strategies.},
Doi = {10.1016/j.cresp.2024.100185},
Key = {fds376092}
}
@article{fds376908,
Author = {Cárdenas-Egúsquiza, AL and Seli, P and Berntsen,
D},
Title = {Associations Between Autobiographical Memory and Dreaming:
An Individual-Differences Approach},
Journal = {Dreaming},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1037/drm0000264},
Abstract = {Autobiographical memory and dreaming are ubiquitous in
everyday life. The study of their relation has largely been
assessed using experimental approaches, abstracting from
individual differences, despite evidence of stable
individual differences in both mental processes. Here, we
examined, for the first time, whether individual differences
in the recollective experience of autobiographical memory
(measured by the Autobiographical Recollection Test [ART];
Berntsen et al., 2019) are associated with individual
differences in dreaming (measured by the Inventory of Dream
Experiences and Attitudes, BeaulieuPrévost et al., 2009) in
a sample of 246 participants. The ART showed consistent and
robust associations with five out of seven aspects of
dreaming, demonstrating that the way people generally
remember their personal past is reliably related to the way
they experience their dreams. The findings provide new
perspectives on the role of autobiographical memory in
dreaming as well as on the continuity hypothesis of
dreaming.},
Doi = {10.1037/drm0000264},
Key = {fds376908}
}
@article{fds371795,
Author = {Bellaiche, L and Shahi, R and Turpin, MH and Ragnhildstveit, A and Sprockett, S and Barr, N and Christensen, A and Seli,
P},
Title = {Humans versus AI: whether and why we prefer human-created
compared to AI-created artwork.},
Journal = {Cognitive research: principles and implications},
Volume = {8},
Number = {1},
Pages = {42},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1186/s41235-023-00499-6},
Abstract = {With the recent proliferation of advanced artificial
intelligence (AI) models capable of mimicking human
artworks, AI creations might soon replace products of human
creativity, although skeptics argue that this outcome is
unlikely. One possible reason this may be unlikely is that,
independent of the physical properties of art, we place
great value on the imbuement of the human experience in art.
An interesting question, then, is whether and why people
might prefer human-compared to AI-created artworks. To
explore these questions, we manipulated the purported
creator of pieces of art by randomly assigning a
"Human-created" or "AI-created" label to paintings actually
created by AI, and then assessed participants' judgements of
the artworks across four rating criteria (Liking, Beauty,
Profundity, and Worth). Study 1 found increased positive
judgements for human- compared to AI-labelled art across
all criteria. Study 2 aimed to replicate and extend Study 1
with additional ratings (Emotion, Story, Meaningful, Effort,
and Time to create) intended to elucidate why people
more-positively appraise Human-labelled artworks. The main
findings from Study 1 were replicated, with narrativity
(Story) and perceived effort behind artworks (Effort)
moderating the label effects ("Human-created" vs.
"AI-created"), but only for the sensory-level judgements
(Liking, Beauty). Positive personal attitudes toward
AI moderated label effects for more-communicative
judgements (Profundity, Worth). These studies demonstrate
that people tend to be negatively biased against AI-created
artworks relative to purportedly human-created artwork, and
suggest that knowledge of human engagement in the artistic
process contributes positively to appraisals of
art.},
Doi = {10.1186/s41235-023-00499-6},
Key = {fds371795}
}
@article{fds364337,
Author = {Landry, AP and Schooler, JW and Willer, R and Seli,
P},
Title = {Reducing Explicit Blatant Dehumanization by Correcting
Exaggerated Meta-Perceptions},
Journal = {Social Psychological and Personality Science},
Volume = {14},
Number = {4},
Pages = {407-418},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1177/19485506221099146},
Abstract = {If explicitly, blatantly dehumanizing a group of
people—overtly characterizing them as less than
human—facilitates harming them, then reversing this
process is paramount. Addressing dehumanization among
American political partisans appears especially crucial,
given that it has been linked to their anti-democratic
hostility. Perhaps because of its overt nature, partisans
recognize—and greatly exaggerate—the extent to which
out-partisans explicitly, blatantly dehumanize them. Past
research has found that when people perceive they are
dehumanized by an outgroup (i.e., meta-dehumanization), they
respond with reciprocal dehumanization. Therefore, we
reasoned that partisans’ dehumanization could be reduced
by correcting their exaggerated meta-dehumanization. Indeed,
across three preregistered studies (N = 4,154), an
intervention correcting American partisans’ exaggerated
meta-dehumanization reduced their own dehumanization of
out-partisans. This decreased dehumanization persisted at a
1-week follow-up and predicted downstream reductions in
partisans’ anti-democratic hostility, suggesting that
correcting exaggerated meta-dehumanization can durably
mitigate the dark specter of dehumanization.},
Doi = {10.1177/19485506221099146},
Key = {fds364337}
}
@article{fds369746,
Author = {Brendle, M and Ragnhildstveit, A and Slayton, M and Smart, L and Cunningham, S and Zimmerman, MH and Seli, P and Gaffrey, MS and Averill,
LA and Robison, R},
Title = {Registered clinical trials investigating ketamine and
esketamine for treatment-resistant depression: A systematic
review},
Journal = {Journal of Psychedelic Studies},
Volume = {6},
Number = {3},
Pages = {176-187},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1556/2054.2022.00234},
Abstract = {Background and Aims: Ketamine and esketamine have garnered
interest in both psychiatric research and clinical practice
for treatment-resistant depression (TRD). In this review, we
examined registered trials investigating the therapeutic use
of ketamine or esketamine for TRD, with the aim of
characterizing emerging trends and knowledge gaps. Methods:
The ClinicalTrials.gov electronic registry and results
database was queried from inception to February 5, 2022,
adhering to elements of the PRISMA guideline, we evaluated
trial eligibility in the qualitative synthesis. Data
regarding study design, drug regimens, and measures were
subsequently abstracted and descriptively analyzed. Results:
The search returned 86 records, of which 56 trials were
included in the final review. The number of trials
investigating ketamine and esketamine for TRD increased
since 2008, with higher peaks observed in 2015 (n = 9) and
2021 (n = 9). Most trials were Phase 2 (13, 23.2%) or Phase
3 (11, 19.6%), gathering preliminary data on efficacy and/or
further data on safety and efficacy with variant dosing and
pharmacological approaches. By and large, trials examined
ketamine and esketamine as individual versus combination
treatments (45% and 25%, respectively). The
Montgomery-Asberg Depression Rating Scale (MADRS) was most
commonly used to assess clinical outcomes (75%).
Conclusions: There are increasingly large-scale and
late-phase trials of esketamine over ketamine for TRD,
coupled with efforts to centralize evidence on these
medications. Yet several trials do not assess patient
characteristics that may affect treatment response, such as
age, sex, and race. By understanding these design
limitations, scientists and clinicians can avoid research
waste and funding bodies can judiciously direct support
towards high priority research.},
Doi = {10.1556/2054.2022.00234},
Key = {fds369746}
}
@article{fds352862,
Author = {Brosowsky, NP and DeGutis, J and Esterman, M and Smilek, D and Seli,
P},
Title = {Mind Wandering, Motivation, and Task Performance Over Time:
Evidence That Motivation Insulates People From the Negative
Effects of Mind Wandering},
Journal = {Psychology of Consciousness: Theory Research, and
Practice},
Volume = {10},
Number = {4},
Pages = {475-486},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1037/cns0000263},
Abstract = {In the current study, we examined whether participant
motivation was associated with fluctuations of attentional
engagement and performance over time. We gauged
participants’ motivation and depth of mind wandering as
they completed the metronome response task to determine
whether fluctuations in inattention (indexed by task
performance and depth of mind wandering) would be related to
fluctuations in motivation. As in prior work, we found that,
with increasing time on task, (a) self-reported depth of
mind wandering increased, (b) task performance decreased,
and (c) motivation waned. Extending this work, we found an
interaction between motivation and mind wandering such that
mind wandering was negatively associated with task
performance when motivation was low, but unrelated to
performance when motivation was high. These results suggest
that motivation may help improve task performance by
reducing the depth of mind wandering, while also providing
insulation from the negative effects of mind wandering, when
it does occur.},
Doi = {10.1037/cns0000263},
Key = {fds352862}
}
@article{fds362396,
Author = {Jansen, EJ and Danckert, J and Seli, P and Scholer,
AA},
Title = {Under pressure: Locomotion and assessment in the COVID-19
pandemic},
Journal = {Self and Identity},
Volume = {22},
Number = {1},
Pages = {1-18},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/15298868.2022.2036635},
Abstract = {The COVID-19 pandemic poses unique opportunities to explore
how fundamental self-regulatory variables affect responses
to the pandemic. We examine how two critical self-regulatory
orientations, locomotion and assessment, relate to
psychological distress and obeying public health guidelines
using secondary data analysis. In the initial pandemic
stages (April and May, 2020), North American participants (N
= 924) completed measures of chronic locomotion and
assessment, pandemic behaviors and feelings, and various
individual-differences. Analyses revealed that assessment,
but not locomotion, was indirectly associated with greater
pandemic rule-breaking and psychological distress through
the fear of missing out, difficulty engaging in activities,
and engagement in negative activities. We discuss why the
vulnerabilities of assessment, and not locomotion, may be
particularly sensitive to pandemic-related
constraints.},
Doi = {10.1080/15298868.2022.2036635},
Key = {fds362396}
}
@article{fds367264,
Author = {Smith, AC and Brosowsky, NP and Caron, EE and Seli, P and Smilek,
D},
Title = {Examining the relation between mind wandering and unhealthy
eating behaviours},
Journal = {Personality and Individual Differences},
Volume = {200},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1016/j.paid.2022.111908},
Abstract = {In the present study, we explored how individual differences
in the tendency to mind-wander are related to unhealthy
eating behaviours (i.e., eating habits and eating-disorder
symptoms). Given that eating-disorders are associated with
inhibition (extreme control) and impulsivity (a lack of
control), we were interested in how unhealthy eating
behaviours might relate to both spontaneous mind-wandering,
which is often construed as a failure of executive control,
and deliberate mind-wandering, which is thought to occur via
controlled processes. To ensure that any observed relations
were not driven by self-control, we also measured and
statistically controlled for this variable. In a large,
non-clinical sample (N = 2328), regression analyses
predicting each of the eating measures with self-control,
spontaneous mind-wandering, and deliberate mind-wandering
revealed that self-control and spontaneous mind-wandering
were significantly positively predictive of unhealthy eating
behaviours, whereas deliberate mind-wandering did not
significantly predict these measures. These findings suggest
that spontaneous, but not deliberate, mind-wandering has a
robust unique relation with unhealthy eating behaviours,
even when controlling for self-control.},
Doi = {10.1016/j.paid.2022.111908},
Key = {fds367264}
}
@article{fds369859,
Author = {Ragnhildstveit, A and Kaiyo, M and Snyder, MB and Jackson, LK and Lopez,
A and Mayo, C and Miranda, AC and August, RJ and Seli, P and Robison, R and Averill, LA},
Title = {Cannabis-assisted psychotherapy for complex dissociative
posttraumatic stress disorder: A case report.},
Journal = {Frontiers in psychiatry},
Volume = {14},
Pages = {1051542},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.3389/fpsyt.2023.1051542},
Abstract = {<h4>Background</h4>A dissociative subtype of posttraumatic
stress disorder, known as "D-PTSD", has been included in the
Diagnostic and Statistical Manual of Mental Disorders, Fifth
Edition. In addition to meeting criteria for PTSD, patients
endorse prominent dissociative symptoms, namely
depersonalization and derealization, or detachment from
one's self and surroundings. At present, this population is
supported by a highly heterogeneous and undeveloped
literature. Targeted interventions are therefore lacking,
and those indicated for PTSD are limited by poor efficacy,
delayed onset of action, and low patient engagement. Here,
we introduce cannabis-assisted psychotherapy (CAP) as a
novel treatment for D-PTSD, drawing parallels to psychedelic
therapy.<h4>Case presentation</h4>A 28-year-old female
presented with complex D-PTSD. In a naturalistic setting,
she underwent 10 sessions of CAP, scheduled twice monthly
over 5 months, coupled with integrative cognitive behavioral
therapy. An autonomic and relational approach to CAP was
leveraged, specifically psychedelic somatic interactional
psychotherapy. Acute effects included oceanic boundlessness,
ego dissolution, and emotional breakthrough. From baseline
to post-treatment, the patient showed a 98.5% reduction in
pathological dissociation, as measured by the
Multidimensional Inventory of Dissociation, no longer
meeting criteria for D-PTSD. This was accompanied by
decreased cognitive distractibility and emotional suffering,
as well as increased psychosocial functioning. Anecdotally,
the patient has sustained improvements for over 2 years to
date.<h4>Conclusions</h4>There is urgency to identify
treatments for D-PTSD. The present case, while inherently
limited, underscores the potential of CAP as a therapeutic
option, leading to robust and sustained improvement.
Subjective effects were comparable to those produced by
classic and non-classic psychedelics, such as psilocybin and
ketamine. Further research is warranted to explore,
establish, and optimize CAP in D-PTSD, and to characterize
its role in the pharmacological landscape.},
Doi = {10.3389/fpsyt.2023.1051542},
Key = {fds369859}
}
@article{fds372414,
Author = {Bellaiche, L and Smith, AP and Barr, N and Christensen, A and Williams,
C and Ragnhildstveit, A and Schooler, J and Beaty, R and Chatterjee, A and Seli, P},
Title = {Back to the basics: Abstract painting as an index of
creativity},
Journal = {Creativity Research Journal},
Volume = {35},
Number = {4},
Pages = {698-713},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/10400419.2023.2243100},
Abstract = {Researchers have invested a great deal in creating reliable,
“gold-standard” creativity assessments that can be
administered in controlled laboratory settings, though these
efforts have come at the cost of not using ecologically and
face-valid tasks. To help fill this critical gap, we
developed and implemented a novel, face-valid paradigm that
required participants to paint abstract pieces of art, which
were later rated for creative quality. We first sought to
evaluate whether there was good convergence among creativity
ratings provided by independent raters. Next, we examined
whether its measure of creativity correlated with (a)
existing creativity measures and (b) individual traits (e.g.
openness, fluid intelligence) that are typically correlated
with indices of creativity. Our findings indicate that our
abstract-painting paradigm is feasible to implement
(independent ratings of the creativity of the paintings
converged well), and that its measure of creativity
significantly correlated with some of the gold-standard
indices of creativity (thereby providing convergent
validity). These findings suggest that having participants
engage in abstract painting provides a valid index of
creativity, thereby opening new opportunities for future
research to index a more-face-valid measure of
creativity.},
Doi = {10.1080/10400419.2023.2243100},
Key = {fds372414}
}
@article{fds374573,
Author = {Ragnhildstveit, A and Khan, R and Seli, P and Bass, LC and August, RJ and Kaiyo, M and Barr, N and Jackson, LK and Gaffrey, MS and Barsuglia, JP and Averill, LA},
Title = {5-MeO-DMT for post-traumatic stress disorder: a real-world
longitudinal case study.},
Journal = {Frontiers in psychiatry},
Volume = {14},
Pages = {1271152},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.3389/fpsyt.2023.1271152},
Abstract = {Psychedelic therapy is, arguably, the next frontier in
psychiatry. It offers a radical alternative to longstanding,
mainstays of treatment, while exciting a paradigm shift in
translational science and drug discovery. There is
particular interest in 5-methoxy-<i>N,N</i>-dimethyltryptamine
(5-MeO-DMT)-a serotonergic psychedelic-as a novel,
fast-acting therapeutic. Yet, few studies have directly
examined 5-MeO-DMT for trauma- or stress-related
psychopathology, including post-traumatic stress disorder
(PTSD). Herein, we present the first longitudinal case study
on 5-MeO-DMT for chronic refractory PTSD, in a 23-year-old
female. A single dose of vaporized bufotoxin of the Sonoran
Desert Toad (<i>Incilius alvarius</i>), containing an
estimated 10-15 mg of 5-MeO-DMT, led to clinically
significant improvements in PTSD, with next-day effects.
This was accompanied by marked reductions in hopelessness
and related suicide risk. Improvements, across all
constructs, were sustained at 1-, 3-, 6-, and 12-months
follow-up, as monitored by a supporting clinician. The
subject further endorsed a complete mystical experience,
hypothesized to underly 5-MeO-DMT's therapeutic activity. No
drug-related, serious adverse events occurred. Together,
results showed that 5-MeO-DMT was generally tolerable, safe
to administer, and effective for PTSD; however, this was not
without risk. The subject reported acute nausea,
overwhelming subjective effects, and late onset of night
terrors. Further research is warranted to replicate and
extend these findings, which are inherently limited,
non-generalizable, and rely on methods not clinically
accepted.},
Doi = {10.3389/fpsyt.2023.1271152},
Key = {fds374573}
}
%% Shan, Yanyan
@article{fds373641,
Author = {Rosenthal, MZ and Shan, Y and Trumbull, J},
Title = {Treatment of Misophonia},
Journal = {Advances in Psychiatry and Behavioral Health},
Volume = {3},
Number = {1},
Pages = {33-41},
Publisher = {Elsevier BV},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1016/j.ypsc.2023.03.009},
Doi = {10.1016/j.ypsc.2023.03.009},
Key = {fds373641}
}
@article{fds373642,
Author = {Shan, Y and Yan, S and Jia, Y and Hu, Y and Rubin, DC and Berntsen,
D},
Title = {The Properties of Involuntary and Voluntary Autobiographical
Memories in Chinese Patients with Depression and Healthy
Individuals},
Journal = {Cognitive Therapy and Research},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1007/s10608-023-10353-0},
Abstract = {Background: Research on depression has largely focused on
negative intrusive memories with little research on general
involuntary memories as they occur in everyday life. In
addition, all studies have been conducted on Western
participants, and there are no studies on general
involuntary memory in Eastern patients with depression.
Methods: Thirty Chinese patients with depression and 30
healthy controls completed a memory diary in which they
recorded a total of 10 involuntary and 10 voluntary
memories. They were requested to fill out corresponding
questionnaires of involuntary and voluntary memories as
well. Results: Both patients with depression and healthy
controls reported involuntary memories that had a more
negative impact, were more specific, and were associated
with more maladaptive emotion regulation when compared to
voluntary memories. For both retrieval modes, patients with
depression reported more negative and fewer positive
memories, more negative and less positive mood impact, more
avoidance, rumination, worry, negative interpretation, and
less positive interpretation in response to the memories.
Patients with depression rated their memories as more
central, less specific, and rehearsed more frequently.
Negative mood impact and maladaptive emotion regulation
associated with involuntary memories were amplified in
depression. Conclusions: These findings support the view
that general involuntary memories could be a potential
target to promote the treatment for depression.},
Doi = {10.1007/s10608-023-10353-0},
Key = {fds373642}
}
@article{fds373643,
Author = {Zhong, S and Chen, N and Lai, S and Shan, Y and Li, Z and Chen, J and Luo, A and Zhang, Y and Lv, S and He, J and Wang, Y and Yao, Z and Jia,
Y},
Title = {Association between cognitive impairments and aberrant
dynamism of overlapping brain sub-networks in unmedicated
major depressive disorder: A resting-state MEG
study},
Journal = {Journal of Affective Disorders},
Volume = {320},
Pages = {576-589},
Publisher = {Elsevier BV},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1016/j.jad.2022.09.069},
Doi = {10.1016/j.jad.2022.09.069},
Key = {fds373643}
}
%% Sherwood, Andrew
@article{fds376270,
Author = {Sherwood, A and Ulmer, C and Wu, JQ and Blumenthal, JA and Herold, E and Smith, PJ and Koch, GG and Johnson, K and Viera, A and Edinger, J and Hinderliter, A},
Title = {Cognitive behavior therapy for insomnia for untreated
hypertension with comorbid insomnia disorder: The SLEEPRIGHT
clinical trial.},
Journal = {J Clin Hypertens (Greenwich)},
Volume = {26},
Number = {4},
Pages = {441-447},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1111/jch.14763},
Abstract = {Insomnia and poor sleep are associated with an increased
risk of developing cardiovascular disease (CVD) and its
precursors, including hypertension. In 2022, the American
Heart Association (AHA) added inadequate sleep to its list
of health behaviors that increase the risk for CVD. It
remains unknown, however, whether the successful treatment
of insomnia and inadequate sleep can reduce heightened CVD
risk. SLEEPRIGHT is a single-site, prospective clinical
trial designed to evaluate whether the successful treatment
of insomnia results in improved markers of CVD risk in
patients with untreated hypertension and comorbid insomnia
disorder. Participants (N = 150) will undergo baseline
assessments, followed by a 6-week run-in period after which
they will receive cognitive behavior therapy for insomnia
(CBT-I), comprised of 6 hourly sessions with an experienced
CBT-I therapist over a 6-week period. In addition to
measures of insomnia severity, as well as both subjective
and objective measures of sleep, the primary outcome
measures are nighttime blood pressure (BP) and BP dipping
assessed by 24-h ambulatory BP monitoring (ABPM). Secondary
outcomes include several CVD risk biomarkers, including
clinic BP, lipid profile, vascular endothelial function,
arterial stiffness, and sympathetic nervous system (SNS)
activity. Data analysis will evaluate the association
between improvements in insomnia and sleep with primary and
secondary CVD risk biomarker outcomes. The SLEEPRIGHT trial
(ClinicalTrials.Gov NCT04009447) will utilize CBT-I, the
current gold standard treatment for insomnia disorder, to
evaluate whether reducing insomnia severity and improving
sleep are accompanied by improved biomarkers of CVD risk in
patients with untreated hypertension.},
Doi = {10.1111/jch.14763},
Key = {fds376270}
}
@article{fds371021,
Author = {Blumenthal, JA and Smith, PJ and Mabe, S and Hinderliter, A and Craighead, L and Watkins, LL and Ingle, K and Tyson, CC and Lin, P-H and Kraus, WE and Liao, L and Sherwood, A},
Title = {Effects of Lifestyle Modification on Psychosocial Function
in Patients With Resistant Hypertension: SECONDARY OUTCOMES
FROM THE TRIUMPH RANDOMIZED CLINICAL TRIAL.},
Journal = {J Cardiopulm Rehabil Prev},
Volume = {44},
Number = {1},
Pages = {64-70},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1097/HCR.0000000000000801},
Abstract = {PURPOSE: In a secondary analysis of the TRIUMPH clinical
trial, psychological outcomes in patients with resistant
hypertension (RH) receiving a diet and exercise intervention
delivered in a cardiac rehabilitation setting were compared
with those receiving a similar prescription of diet and
exercise provided in a single counseling session by a health
educator. METHODS: One hundred forty patients with RH were
randomly assigned to a 4-mo program of dietary counseling,
behavioral weight management, and exercise (C-LIFE) or a
single counseling session providing standardized education
and physician advice (SEPA). Participants completed a
battery of questionnaires to assess psychological
functioning before and after the intervention. A global
measure of psychological functioning was derived from the
General Health Questionnaire (GHQ), Perceived Stress Scale
(PSS), Medical Outcomes Study 36-item Short Form Health
Survey, Spielberger State-Trait Anxiety Inventory, Hospital
Anxiety and Depression Scale (HADS), Beck Depression
Inventory-II, and Patient-Reported Outcomes Measurement
Information System (PROMIS) Anger scale. RESULTS:
Participants in the C-LIFE intervention achieved greater
improvements in psychological functioning compared with SEPA
(C-LIFE: 58.9 [56.1, 61.8] vs SEPA: 66.5 [62.1, 70.9]; P =
.024). Greater improvements were especially evident for the
GHQ, PSS, and HADS. Examination of mediation revealed that
greater weight loss ( B =-0.17, P = .004) and improved
oxygen uptake ( B =-0.12, P = .044) were associated with
improved psychological functioning. CONCLUSION: Compared
with standard education and physician advice, a structured
program of diet and exercise not only reduced blood pressure
but also improved psychological functioning in patients with
RH.},
Doi = {10.1097/HCR.0000000000000801},
Key = {fds371021}
}
@article{fds373636,
Author = {Ulmer, CS and Taylor, KA and Campbell, AA and Sherwood, A and Wu, JQ and Beckham, JC and Hoerle, JM and Augustine, AV and VA Mid-Atlantic
MIRECC},
Title = {Response to letter to the editor: sleep breathing at the
intersection of nightmares and cardiovascular
risk.},
Journal = {Sleep},
Volume = {46},
Number = {11},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1093/sleep/zsad221},
Doi = {10.1093/sleep/zsad221},
Key = {fds373636}
}
@article{fds371881,
Author = {Ribeiro, F and Teixeira, M and Alves, AJ and Sherwood, A and Blumenthal,
JA},
Title = {Lifestyle Medicine as a Treatment for Resistant
Hypertension.},
Journal = {Curr Hypertens Rep},
Volume = {25},
Number = {10},
Pages = {313-328},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1007/s11906-023-01253-5},
Abstract = {PURPOSE OF REVIEW: Approximately 10% of the adults with
hypertension fail to achieve the recommended blood
pressure treatment targets on 3 antihypertensive medications
or require ≥ 4 medications to achieve goal. These
patients with 'resistant hypertension' have an increased
risk of target organ damage, adverse clinical events, and
all-cause mortality. Although lifestyle modification is
widely recommended as a first-line approach for the
management of high blood pressure, the effects of lifestyle
modifications in patients with resistant hypertension has
not been widely studied. This review aims to provide an
overview of the emerging evidence on the benefits of
lifestyle modifications in patients with resistant
hypertension, reviews potential mechanisms by which
lifestyles may reduce blood pressure, and discusses the
clinical implications of the recent findings in this field.
RECENT FINDINGS: Evidence from single-component randomized
clinical trials demonstrated that aerobic exercise, weight
loss and dietary modification can reduce clinic and
ambulatory blood pressure in patients with resistant
hypertension. Moreover, evidence from multi-component trials
involving exercise and dietary modification and weight
management can facilitate lifestyle change, reduce clinic
and ambulatory blood pressure, and improve biomarkers of
cardiovascular risk. This new evidence supports the efficacy
of lifestyle modifications added to optimized medical
therapy in reducing blood pressure and improving
cardiovascular risk biomarkers in patients with resistant
hypertension. These findings need to be confirmed in larger
studies, and the persistence of benefit over extended
follow-up needs further study.},
Doi = {10.1007/s11906-023-01253-5},
Key = {fds371881}
}
@article{fds370911,
Author = {Watkins, LL and LoSavio, ST and Calhoun, P and Resick, PA and Sherwood,
A and Coffman, CJ and Kirby, AC and Beaver, TA and Dennis, MF and Beckham,
JC},
Title = {Effect of cognitive processing therapy on markers of
cardiovascular risk in posttraumatic stress disorder
patients: A randomized clinical trial.},
Journal = {J Psychosom Res},
Volume = {170},
Pages = {111351},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1016/j.jpsychores.2023.111351},
Abstract = {OBJECTIVE: Posttraumatic stress disorder (PTSD) is
associated with elevated risk of coronary heart disease
(CHD); however, the effects of PTSD treatment on CHD
biomarkers is unknown. This study examined whether cognitive
processing therapy (CPT) improves 24-hourheart rate
variability (HRV), a predictor of CHD mortality. METHODS:
Individuals between the ages of 40 and 65 years with PTSD
(n = 112) were randomized to receive 12 sessions of CPT or
a Waiting List (WL) intervention comprised of 6 weekly
telephone checks of emotional status. The primary outcome
variable was 24-hour HRV estimated from the standard
deviation of all normal R-R intervals (SDNN); secondary
outcomes were the root mean square of successive differences
between heart beats (RMSSD), low-frequency HRV (LF-HRV) and
high-frequency HRV (HF-HRV). Secondary outcomes also
included 24-hour urinary catecholamine excretion, plasma
C-reactive protein (CRP), and flow-mediated dilation (FMD)
of the brachial artery. For outcomes, linear mixed
longitudinal models were used to estimate mean differences
(Mdiff). RESULTS: Participants randomized to the CPT group
did not show improved SDNN (Mdiff = 9.8; 95%CI, -2.7 to
22.3; p = 0.12), the primary outcome variable, but showed
improved RMSSD (Mdiff = 3.8; 95% CI, 0.5 to 7.1;
p = 0.02), LF- HRV (Mdiff =0.3; 95% CI, 0.1 to 0.5;
p = 0.01), and HF-HRV (Mdiff = 0.3; 95% CI, 0.0 to 0.6;
p = 0.03) compared to WL. There were no differences
between groups in catecholamine excretion, FMD, or
inflammatory markers. CONCLUSION: Treating PTSD may not only
improve quality of life but may also help ameliorate
heightened CHD risk characteristics of PTSD.},
Doi = {10.1016/j.jpsychores.2023.111351},
Key = {fds370911}
}
@article{fds370110,
Author = {Campbell, AA and Taylor, KA and Augustine, AV and Sherwood, A and Wu,
JQ and Beckham, JC and Hoerle, JM and VA Mid-Atlantic MIRECC, and Ulmer, CS},
Title = {Nightmares: an independent risk factor for cardiovascular
disease?},
Journal = {Sleep},
Volume = {46},
Number = {6},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1093/sleep/zsad089},
Abstract = {STUDY OBJECTIVES: Prior work has established associations
between post-traumatic stress disorder (PTSD), disrupted
sleep, and cardiovascular disease (CVD), but few studies
have examined health correlates of nightmares beyond risks
conferred by PTSD. This study examined associations between
nightmares and CVD in military veterans. METHODS:
Participants were veterans (N = 3468; 77% male) serving
since September 11, 2001, aged 38 years (SD = 10.4);
approximately 30% were diagnosed with PTSD. Nightmare
frequency and severity were assessed using the Davidson
Trauma Scale (DTS). Self-reported medical issues were
assessed using the National Vietnam Veterans Readjustment
Study Self-report Medical Questionnaire. Mental health
disorders were established using the Structured Clinical
Interview for DSM-IV. The sample was stratified by the
presence or absence of PTSD. Within-group associations
between nightmare frequency and severity and self-reported
CVD conditions, adjusting for age, sex, race, current
smoking, depression, and sleep duration. RESULTS: Frequent
and severe nightmares during the past week were endorsed by
32% and 35% of participants, respectively. Those endorsing
nightmares that were frequent, severe, and the combination
thereof were more likely to also evidence high blood
pressure (ORs 1.42, OR 1.56, and OR 1.47, respectively) and
heart problems (OR 1.43, OR 1.48, and OR 1.59, respectively)
after adjusting for PTSD diagnosis and other covariates.
CONCLUSIONS: Nightmare frequency and severity among veterans
are associated with cardiovascular conditions, even after
controlling for PTSD diagnosis. Study findings suggest that
nightmares may be an independent risk factor for CVD.
Additional research is needed to validate these findings
using confirmed diagnoses and explore potential
mechanisms.},
Doi = {10.1093/sleep/zsad089},
Key = {fds370110}
}
@article{fds368556,
Author = {Avorgbedor, F and Blumenthal, JA and Hinderliter, A and Ingle, K and Lin, P-H and Craighead, L and Tyson, C and Kraus, W and Sherwood, A and Smith, PJ},
Title = {Inflammation moderates the effects of lifestyle modification
on neurocognition among individuals with resistant
hypertension.},
Journal = {J Clin Hypertens (Greenwich)},
Volume = {25},
Number = {1},
Pages = {106-110},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1111/jch.14591},
Abstract = {Individuals with resistant hypertension (RH) have the
greatest risk of cerebrovascular disease and cognitive
impairment among individuals with hypertension. Elevated
levels of pro-inflammatory cytokines may represent a
critical yet unexamined factor influencing the impact of
healthy lifestyle changes on cognitive function. We explored
the influence of inflammation on changes in cognition
following lifestyle modification among individuals with RH
participating in the TRIUMPH clinical trial. One hundred
forty participants with RH completed a battery of
neurocognitive tests along with the inflammatory marker
C-reactive protein (hsCRP) and were subsequently randomized
to an intensive 4-month lifestyle modification intervention
or to education and physician advice control. Results
indicated that the effects of lifestyle modification on
Executive Function and Learning were moderated by
pre-intervention hsCRP levels (P = .049), with treatment
efficacy increasing across levels of baseline inflammation
levels (low: d = 0.12; mild: d = 0.43; moderate:
d = 0.81). We conclude that inflammatory profiles may help
identify individuals more likely to improve executive
functioning resulting from lifestyle modification.},
Doi = {10.1111/jch.14591},
Key = {fds368556}
}
@article{fds371022,
Author = {Smith, PJ and Sherwood, A and Avorgbedor, F and Ingle, KK and Kraus, WE and Hinderliter, AE and Blumenthal, JA},
Title = {Sleep Quality, Metabolic Function, Physical Activity, and
Neurocognition Among Individuals with Resistant
Hypertension.},
Journal = {J Alzheimers Dis},
Volume = {93},
Number = {3},
Pages = {995-1006},
Year = {2023},
url = {http://dx.doi.org/10.3233/JAD-230029},
Abstract = {BACKGROUND: Resistant hypertension (RH) is a major risk
factor for stroke, cognitive decline, and dementia. Sleep
quality is increasingly suggested to play an important role
linking RH to cognitive outcomes, although the mechanisms
linking sleep quality to poor cognitive function have yet to
be fully delineated. OBJECTIVE: To delineate biobehavioral
mechanisms linking sleep quality, metabolic function, and
cognitive function among 140 overweight/obese adults with RH
in the TRIUMPH clinical trial. METHODS: Sleep quality was
indexed using actigraphy measures of sleep quality and sleep
fragmentation, as well as self-reported sleep quality from
the Pittsburgh Sleep Quality Index (PSQI). Cognitive
function was assessed using a 45-minute battery assessing
executive function, processing speed, and memory.
Participants were randomized to a cardiac
rehabilitation-based lifestyle program (C-LIFE) or a
standardized education and physician advice condition (SEPA)
for 4 months. RESULTS: Better sleep quality at baseline was
associated with better executive function (B = 0.18
p = 0.027), as well as greater fitness (B = 0.27,
p = 0.007) and lower HBA1c (B = -0.25,
p = 0.010). Cross-sectional analyses revealed that the
sleep quality executive function association was mediated by
HBA1c (B = 0.71 [0.05, 2.05]). C-LIFE improved sleep
quality (-1.1 [-1.5, -0.6] versus+-0.1 [-0.8, 0.7]) and
actigraphy steps (+922 [529, 1316] versus+56 [-548, 661]),
with actigraphy mediating improvements in executive function
(B = 0.40 [0.02, 1.07]). CONCLUSION: Better metabolic
function and improved physical activity patterns levels play
important roles linking sleep quality and executive function
in RH.},
Doi = {10.3233/JAD-230029},
Key = {fds371022}
}
%% Siegler, Ilene C.
@article{fds374927,
Author = {Andonian, BJ and Ross, LM and Sudnick, AM and Johnson, JL and Pieper,
CF and Belski, KB and Counts, JD and King, AP and Wallis, JT and Bennett,
WC and Gillespie, JC and Moertl, KM and Richard, D and Huebner, JL and Connelly, MA and Siegler, IC and Kraus, WE and Bales, CW and Porter
Starr, KN and Huffman, KM},
Title = {Effect of Remotely Supervised Weight Loss and Exercise
Training Versus Lifestyle Counseling on Cardiovascular Risk
and Clinical Outcomes in Older Adults With Rheumatoid
Arthritis: A Randomized Controlled Trial.},
Journal = {Acr Open Rheumatol},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1002/acr2.11639},
Abstract = {OBJECTIVE: To compare a remotely supervised weight loss and
exercise intervention to lifestyle counseling for effects on
cardiovascular disease risk, disease activity, and
patient-reported outcomes in older patients with rheumatoid
arthritis (RA) and overweight/obesity. METHODS: Twenty older
(60-80 years), previously sedentary participants with
seropositive RA and overweight/obesity were randomized to
16 weeks of either Supervised Weight loss and Exercise
Training (SWET) or Counseling Health As Treatment (CHAT).
The SWET group completed aerobic training (150 minutes/week
moderate-to-vigorous intensity), resistance training (two
days/week), and a hypocaloric diet (7% weight loss goal).
The CHAT control group completed two lifestyle counseling
sessions followed by monthly check-ins. The primary outcome
was a composite metabolic syndrome z-score (MSSc) derived
from fasting glucose, triglycerides, high density
lipoprotein-cholesterol, minimal waist circumference, and
mean arterial pressure. Secondary outcomes included RA
disease activity and patient-reported outcomes. RESULTS:
Both groups improved MSSc (absolute change -1.67 ± 0.64
in SWET; -1.34 ± 1.30 in CHAT; P < 0.01 for both
groups) with no between-group difference. Compared with
CHAT, SWET significantly improved body weight, fat mass,
Disease Activity Score-28 C-reactive protein, and
patient-reported physical health, physical function, mental
health, and fatigue (P < 0.04 for all between-group
comparisons). Based on canonical correlations for fat mass,
cardiorespiratory fitness, and leg strength,
component-specific effects were strongest for (1) weight
loss improving MSSc, physical health, and mental health; (2)
aerobic training improving physical function and fatigue;
and (3) resistance training improving Disease Activity
Score-28 C-reactive protein. CONCLUSION: In older patients
with RA and overweight/obesity, 16 weeks of remotely
supervised weight loss, aerobic training, and resistance
training improve cardiometabolic health, patient-reported
outcomes, and disease activity. Less intensive lifestyle
counseling similarly improves cardiovascular disease risk
profiles, suggesting an important role for integrative
interventions in the routine clinical care of this at-risk
RA population.},
Doi = {10.1002/acr2.11639},
Key = {fds374927}
}
@article{fds370527,
Author = {Andonian, B and Ross, LM and Zidek, AM and Fos, LB and Piner, LW and Johnson, JL and Belski, KB and Counts, JD and Pieper, CF and Siegler,
IC and Bales, CW and Porter Starr and KN and Kraus, WE and Huffman,
KM},
Title = {Remotely Supervised Weight Loss and Exercise Training to
Improve Rheumatoid Arthritis Cardiovascular Risk: Rationale
and Design of the Supervised Weight Loss Plus Exercise
Training-Rheumatoid Arthritis Trial.},
Journal = {Acr Open Rheumatol},
Volume = {5},
Number = {5},
Pages = {252-263},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1002/acr2.11536},
Abstract = {Patients with rheumatoid arthritis (RA) remain at an
increased risk for cardiovascular disease (CVD) and
mortality. RA CVD results from a combination of traditional
risk factors and RA-related systemic inflammation. One
hypothetical means of improving overall RA CVD risk is
through reduction of excess body weight and increased
physical activity. Together, weight loss and physical
activity can improve traditional cardiometabolic health
through fat mass loss, while also improving skeletal muscle
health. Additionally, disease-related CVD risk may improve
as both fat mass loss and exercise reduce systemic
inflammation. To explore this hypothesis, 26 older persons
with RA and overweight/obesity will be randomized to
16 weeks of a usual care control arm or to a remotely
Supervised Weight Loss Plus Exercise Training (SWET)
program. A caloric restriction diet (targeting 7% weight
loss) will occur via a dietitian-led intervention, with
weekly weigh-ins and group support sessions. Exercise
training will consist of both aerobic training (150
minutes/week moderate-to-vigorous exercise) and resistance
training (twice weekly). The SWET remote program will be
delivered via a combination of video conference, the study
YouTube channel, and study mobile applications. The primary
cardiometabolic outcome is the metabolic syndrome Z score,
calculated from blood pressure, waist circumference,
high-density lipoprotein cholesterol, triglycerides, and
glucose. RA-specific CVD risk will be assessed with measures
of systemic inflammation, disease activity, patient-reported
outcomes, and immune cell function. The SWET-RA trial will
be the first to assess whether a remotely supervised,
combined lifestyle intervention improves cardiometabolic
health in an at-risk population of older individuals with RA
and overweight/obesity.},
Doi = {10.1002/acr2.11536},
Key = {fds370527}
}
@article{fds371488,
Author = {Collins, KA and Huffman, KM and Wolever, RQ and Smith, PJ and Ross, LM and Siegler, IC and Jakicic, JM and Costa, PT and Kraus,
WE},
Title = {Demographic, Clinical, and Psychosocial Predictors of
Exercise Adherence: The STRRIDE Trials.},
Journal = {Translational Journal of the American College of Sports
Medicine},
Volume = {8},
Number = {3},
Year = {2023},
url = {http://dx.doi.org/10.1249/tjx.0000000000000229},
Abstract = {PURPOSE: To identify baseline demographic, clinical, and
psychosocial predictors of exercise intervention adherence
in the Studies of a Targeted Risk Reduction Intervention
through Defined Exercise (STRRIDE) trials. METHODS: A total
of 947 adults with dyslipidemia or prediabetes were enrolled
into an inactive control group or one of ten exercise
interventions with doses of 10-23 kcal/kg/week, intensities
of 40-80% of peak oxygen consumption, and training for
6-8-months. Two groups included resistance training. Mean
percent aerobic and resistance adherence were calculated as
the amount completed divided by the prescribed weekly
minutes or total sets of exercise times 100, respectively.
Thirty-eight clinical, demographic, and psychosocial
measures were considered for three separate models: 1)
clinical + demographic factors, 2) psychosocial factors, and
3) all measures. A backward bootstrapped variable selection
algorithm and multiple regressions were performed for each
model. RESULTS: In the clinical and demographic measures
model (n=947), variables explained 16.7% of the variance in
adherence (p<0.001); lesser fasting glucose explained the
greatest amount of variance (partial R2 = 3.2%). In the
psychosocial factors model (n=561), variables explained
19.3% of the variance in adherence (p<0.001); greater
36-Item Short Form Health Survey (SF-36) physical component
score explained the greatest amount of variance (partial R2
= 8.7%). In the model with all clinical, demographic, and
psychosocial measures (n=561), variables explained 22.1% of
the variance (p<0.001); greater SF-36 physical component
score explained the greatest amount of variance (partial R2
= 8.9%). SF-36 physical component score was the only
variable to account for >5% of the variance in adherence in
any of the models. CONCLUSIONS: Baseline demographic,
clinical, and psychosocial variables explain approximately
22% of the variance in exercise adherence. The limited
variance explained suggests future research should
investigate additional measures to better identify
participants who are at risk for poor exercise intervention
adherence.},
Doi = {10.1249/tjx.0000000000000229},
Key = {fds371488}
}
@article{fds372235,
Author = {Collins, KA and Huffman, KM and Wolever, RQ and Smith, PJ and Siegler,
IC and Ross, LM and Jakicic, JM and Costa, PT and Kraus,
WE},
Title = {Race and sex differences in dropout from the STRRIDE
trials.},
Journal = {Frontiers in Sports and Active Living},
Volume = {5},
Pages = {1215704},
Year = {2023},
url = {http://dx.doi.org/10.3389/fspor.2023.1215704},
Abstract = {PURPOSE: To determine if race and sex differences exist in
determinants and timing of dropout among individuals
enrolled in an exercise and/or caloric restriction
intervention. METHODS: A total of 947 adults with
dyslipidemia (STRRIDE I, STRRIDE AT/RT) or prediabetes
(STRRIDE-PD) were randomized to either inactive control or
to 1 of 10 exercise interventions, ranging from doses of
8-23 kcal/kg/week, intensities of 50%-75% V˙O2 peak, and
durations of 6-8 months. Two groups included resistance
training, and one included a dietary intervention (7% weight
loss goal). Dropout was defined as an individual withdrawn
from the study, with the reasons for dropout aggregated into
determinant categories. Timing of dropout was defined as the
last session attended and aggregated into phases (i.e.,
"ramp" period to allow gradual adaptation to exercise
prescription). Utilizing descriptive statistics, percentages
were generated according to categories of determinants and
timing of dropout to describe the proportion of individuals
who fell within each category. RESULTS: Black men and women
were more likely to be lost to follow-up (Black men: 31.3%
and Black women: 19.6%), or dropout due to work
responsibilities (15.6% and 12.5%), "change of mind" (12.5%
and 8.9%), transportation issues (6.3% and 3.6%), or
reported lack of motivation (6.3% and 3.6%). Women in
general noted lack of time more often than men as a reason
for dropout (White women: 22.4% and Black women: 22.1%).
Regardless of race and sex, most participants dropped out
during the ramp period of the exercise intervention; with
Black women (50%) and White men (37.1%) having the highest
dropout rate during this period. CONCLUSION: These findings
emphasize the importance of targeted retention strategies
when aiming to address race and sex differences that exist
in determinants and timing of dropout among individuals
enrolled in an exercise and/or caloric restriction
intervention.},
Doi = {10.3389/fspor.2023.1215704},
Key = {fds372235}
}
%% Sinnott-Armstrong, Walter
@article{fds372262,
Author = {McKee, P and Kim, H-E and Tang, H and Everett, JAC and Chituc, V and Gibea,
T and Marques, LM and Boggio, P and Sinnott-Armstrong,
W},
Title = {Does it matter who harmed whom? A cross-cultural study of
moral judgments about harm by and to insiders and
outsiders.},
Journal = {Current psychology (New Brunswick, N.J.)},
Volume = {43},
Number = {9},
Pages = {7997-8007},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1007/s12144-023-04986-3},
Abstract = {This cross-cultural study compared judgments of moral
wrongness for physical and emotional harm with varying
combinations of in-group vs. out-group agents and victims
across six countries: the United States of America
(N = 937), the United Kingdom (N = 995), Romania
(N = 782), Brazil (N = 856), South Korea
(N = 1776), and China (N = 1008). Consistent with
our hypothesis we found evidence of an insider agent effect,
where moral violations committed by outsider agents are
generally considered more morally wrong than the same
violations done by insider agents. We also found support for
an insider victim effect where moral violations that were
committed against an insider victim generally were seen as
more morally wrong than when the same violations were
committed against an outsider, and this effect held across
all countries. These findings provide evidence that the
insider versus outsider status of agents and victims does
affect moral judgments. However, the interactions of these
identities with collectivism, psychological closeness, and
type of harm (emotional or physical) are more complex than
what is suggested by previous literature.<h4>Supplementary
information</h4>The online version contains supplementary
material available at 10.1007/s12144-023-04986-3.},
Doi = {10.1007/s12144-023-04986-3},
Key = {fds372262}
}
@article{fds375504,
Author = {Earp, BD and Porsdam Mann and S and Allen, J and Salloch, S and Suren, V and Jongsma, K and Braun, M and Wilkinson, D and Sinnott-Armstrong, W and Rid, A and Wendler, D and Savulescu, J},
Title = {A Personalized Patient Preference Predictor for Substituted
Judgments in Healthcare: Technically Feasible and Ethically
Desirable.},
Journal = {The American journal of bioethics : AJOB},
Pages = {1-14},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1080/15265161.2023.2296402},
Abstract = {When making substituted judgments for incapacitated
patients, surrogates often struggle to guess what the
patient would want if they had capacity. Surrogates may also
agonize over having the (sole) responsibility of making such
a determination. To address such concerns, a Patient
Preference Predictor (PPP) has been proposed that would use
an algorithm to infer the treatment preferences of
individual patients from population-level data about the
known preferences of people with similar demographic
characteristics. However, critics have suggested that even
if such a PPP were more accurate, on average, than human
surrogates in identifying patient preferences, the proposed
algorithm would nevertheless fail to respect the patient's
(former) autonomy since it draws on the 'wrong' kind of
data: namely, data that are not specific to the individual
patient and which therefore may not reflect their actual
values, or their reasons for having the preferences they do.
Taking such criticisms on board, we here propose a new
approach: the <i>Personalized</i> Patient Preference
Predictor (P4). The P4 is based on recent advances in
machine learning, which allow technologies including large
language models to be more cheaply and efficiently
'fine-tuned' on person-specific data. The P4, unlike the
PPP, would be able to infer an individual patient's
preferences from material (e.g., prior treatment decisions)
that is in fact specific to them. Thus, we argue, in
addition to being potentially more accurate at the
individual level than the previously proposed PPP, the
predictions of a P4 would also more directly reflect each
patient's own reasons and values. In this article, we review
recent discoveries in artificial intelligence research that
suggest a P4 is technically feasible, and argue that, if it
is developed and appropriately deployed, it should assuage
some of the main autonomy-based concerns of critics of the
original PPP. We then consider various objections to our
proposal and offer some tentative replies.},
Doi = {10.1080/15265161.2023.2296402},
Key = {fds375504}
}
@article{fds372776,
Author = {Hopp, FR and Amir, O and Fisher, JT and Grafton, S and Sinnott-Armstrong, W and Weber, R},
Title = {Moral foundations elicit shared and dissociable cortical
activation modulated by political ideology.},
Journal = {Nature human behaviour},
Volume = {7},
Number = {12},
Pages = {2182-2198},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1038/s41562-023-01693-8},
Abstract = {Moral foundations theory (MFT) holds that moral judgements
are driven by modular and ideologically variable moral
foundations but where and how these foundations are
represented in the brain and shaped by political beliefs
remains an open question. Using a moral vignette judgement
task (n = 64), we probed the neural (dis)unity of moral
foundations. Univariate analyses revealed that moral
judgement of moral foundations, versus conventional norms,
reliably recruits core areas implicated in theory of mind.
Yet, multivariate pattern analysis demonstrated that each
moral foundation elicits dissociable neural representations
distributed throughout the cortex. As predicted by MFT,
individuals' liberal or conservative orientation modulated
neural responses to moral foundations. Our results confirm
that each moral foundation recruits domain-general
mechanisms of social cognition but also has a dissociable
neural signature malleable by sociomoral experience. We
discuss these findings in view of unified versus dissociable
accounts of morality and their neurological support for
MFT.},
Doi = {10.1038/s41562-023-01693-8},
Key = {fds372776}
}
@article{fds370405,
Author = {Simmons, C and Helming, K and Musholt, K and Sinnott-Armstrong,
W},
Title = {Where is the golden mean of intellectual humility? Comments
on Ballantyne},
Journal = {Journal of Positive Psychology},
Volume = {18},
Number = {2},
Pages = {240-243},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/17439760.2022.2155227},
Abstract = {In his admirable review, Ballantyne characterizes
intellectual humility (IH) as a personal way ‘to manage
evidence … in seeking truth.’ However, not every way of
managing truth is virtuous. Since IH is supposed to be an
intellectual virtue, we propose that IH should be understood
as a ‘golden mean’ or ‘middle path’ between extremes
of intellectual arrogance and lack of self-confidence (or
between dogmatism and gullibility). The golden mean should
not be characterized descriptively by the statistical mean
of a population but instead either epistemically by accuracy
in intellectual assessments of oneself and others or
pragmatically by the kinds of such assessments that enable
or lead to successful inquiry. This comment explains and
considers advantages and disadvantages of these two ways of
locating the golden mean.},
Doi = {10.1080/17439760.2022.2155227},
Key = {fds370405}
}
@article{fds372817,
Author = {Sinnott-Armstrong, W},
Title = {Dahl’s Definition of Morality},
Journal = {Psychological Inquiry},
Volume = {34},
Number = {2},
Pages = {106-109},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/1047840X.2023.2248853},
Doi = {10.1080/1047840X.2023.2248853},
Key = {fds372817}
}
@article{fds374251,
Author = {Boggio, PS and Rêgo, GG and Everett, JAC and Vieira, GB and Graves, R and Sinnott-Armstrong, W},
Title = {Who did it? Moral wrongness for us and them in the UK, US,
and Brazil},
Journal = {Philosophical Psychology},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1080/09515089.2023.2278637},
Abstract = {Morality has traditionally been described in terms of an
impartial and objective “moral law”, and moral
psychological research has largely followed in this vein,
focusing on abstract moral judgments. But might our moral
judgments be shaped not just by what the action is, but who
is doing it? We looked at ratings of moral wrongness,
manipulating whether the person doing the action was a
friend, a refugee, or a stranger. We looked at these ratings
across various moral foundations, and conducted the study in
Brazil, US, and UK samples. Our most robust and consistent
findings are that purity violations were judged more harshly
when committed by ingroup members and less harshly when
committed by the refugees in comparison to the unspecified
agents, the difference between refugee and unspecified
agents decays from liberals to conservatives, i.e.,
conservatives judge them more harshly than liberals do, and
Brazilians participants are harsher than the US and UK
participants. Our results suggest that purity violations are
judged differently according to who committed them and
according to the political ideology of the judges. We
discuss the findings in light of various theories of groups
dynamics, such as moral hypocrisy, moral disengagement, and
the black sheep effect.},
Doi = {10.1080/09515089.2023.2278637},
Key = {fds374251}
}
@article{fds376731,
Author = {Nadelhoffer, T and Sinnott-Armstrong, W},
Title = {Experimental Ethics},
Volume = {2},
Pages = {206-221},
Booktitle = {The Bloomsbury Handbook of Ethics: 2Nd Edition},
Year = {2023},
Month = {January},
ISBN = {9781350217881},
Key = {fds376731}
}
%% Smith, Caroline
@article{fds370893,
Author = {Smith, CJ and Rendina, DN and Kingsbury, MA and Malacon, KE and Nguyen,
DM and Tran, JJ and Devlin, BA and Raju, RM and Clark, MJ and Burgett, L and Zhang, JH and Cetinbas, M and Sadreyev, RI and Chen, K and Iyer, MS and Bilbo, SD},
Title = {Microbial modulation via cross-fostering prevents the
effects of pervasive environmental stressors on microglia
and social behavior, but not the dopamine
system.},
Journal = {Molecular Psychiatry},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1038/s41380-023-02108-w},
Abstract = {Environmental toxicant exposure, including air pollution, is
increasing worldwide. However, toxicant exposures are not
equitably distributed. Rather, low-income and minority
communities bear the greatest burden, along with higher
levels of psychosocial stress. Both air pollution and
maternal stress during pregnancy have been linked to
neurodevelopmental disorders such as autism, but biological
mechanisms and targets for therapeutic intervention remain
poorly understood. We demonstrate that combined prenatal
exposure to air pollution (diesel exhaust particles, DEP)
and maternal stress (MS) in mice induces social behavior
deficits only in male offspring, in line with the male bias
in autism. These behavioral deficits are accompanied by
changes in microglial morphology and gene expression as well
as decreased dopamine receptor expression and dopaminergic
fiber input in the nucleus accumbens (NAc). Importantly, the
gut-brain axis has been implicated in ASD, and both
microglia and the dopamine system are sensitive to the
composition of the gut microbiome. In line with this, we
find that the composition of the gut microbiome and the
structure of the intestinal epithelium are significantly
shifted in DEP/MS-exposed males. Excitingly, both the
DEP/MS-induced social deficits and microglial alterations in
males are prevented by shifting the gut microbiome at birth
via a cross-fostering procedure. However, while social
deficits in DEP/MS males can be reversed by chemogenetic
activation of dopamine neurons in the ventral tegmental
area, modulation of the gut microbiome does not impact
dopamine endpoints. These findings demonstrate male-specific
changes in the gut-brain axis following DEP/MS and suggest
that the gut microbiome is an important modulator of both
social behavior and microglia.},
Doi = {10.1038/s41380-023-02108-w},
Key = {fds370893}
}
@article{fds369663,
Author = {Bilbo, S and Smith, C and Rendina, D and Kingsbury, M and Malacon, K and Nguyen, D and Tran, J and Devlin, B and Raju, R and Clark, M and Burgett,
L and Zhang, J and Cetinbas, M and Sadreyev, R and Chen, K and Iyer,
M},
Title = {Microbial modulation prevents the effects of pervasive
environmental stressors on microglia and social behavior,
but not the dopamine system.},
Journal = {Res Sq},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.21203/rs.3.rs-2548369/v1},
Abstract = {Environmental toxicant exposure, including air pollution, is
increasing worldwide. However, toxicant exposures are not
equitably distributed. Rather, low-income and minority
communities bear the greatest burden, along with higher
levels of psychosocial stress. Both air pollution and
maternal stress during pregnancy have been linked to
neurodevelopmental disorders such as autism, but biological
mechanisms and targets for therapeutic intervention remain
poorly understood. We demonstrate that combined prenatal
exposure to air pollution (diesel exhaust particles, DEP)
and maternal stress (MS) in mice induces social behavior
deficits only in male offspring, in line with the male bias
in autism. These behavioral deficits are accompanied by
changes in microglial morphology and gene expression as well
as decreased dopamine receptor expression and dopaminergic
fiber input in the nucleus accumbens (NAc). Importantly, the
gut-brain axis has been implicated in ASD, and both
microglia and the dopamine system are sensitive to the
composition of the gut microbiome. In line with this, we
find that the composition of the gut microbiome and the
structure of the intestinal epithelium are significantly
shifted in DEP/MS-exposed males. Excitingly, both the
DEP/MS-induced social deficits and microglial alterations in
males are prevented by shifting the gut microbiome at birth
via a cross-fostering procedure. However, while social
deficits in DEP/MS males can be reversed by chemogenetic
activation of dopamine neurons in the ventral tegmental
area, modulation of the gut microbiome does not impact
dopamine endpoints. These findings demonstrate male-specific
changes in the gut-brain axis following DEP/MS and suggest
that the gut microbiome is an important modulator of both
social behavior and microglia.},
Doi = {10.21203/rs.3.rs-2548369/v1},
Key = {fds369663}
}
%% Smith-Lovin, Lynn
@article{fds376112,
Author = {Quinn, JM and Freeland, RE and Maloney, EK and Rogers, KB and Smith-Lovin, L},
Title = {Meaning Change in U.S. Occupational Identities during the
COVID-19 Pandemic: Was It Temporary or Durable?},
Journal = {Social Psychology Quarterly},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1177/01902725241228529},
Abstract = {The COVID-19 pandemic altered social and economic life in
the United States, displacing many people from their typical
relationship to the institution of work. Our research uses
affect control theory’s measurement structure to examine
how cultural meanings for occupational identities shifted
during the pandemic on the dimensions of evaluation
(good-bad), potency (powerful-powerless), and activity
(lively-inactive). Quinn et al. found that most occupations
were seen as less good and powerful in the early stages of
the pandemic than they were shortly before it began, with
greater evaluation loss for nonessential occupations and
greater potency loss for occupations classified as essential
by state executive orders. We add a third wave to these data
to reassess meanings after the pandemic eased and vaccines
were developed. We use linear mixed modeling to estimate
meaning changes across all three waves and to explore
whether these changes differed for essential versus
nonessential occupations. We find that evaluation and
potency ratings of occupations rebounded over the longer
term—a pattern that fits a control model of stable
cultural meaning. Our results contribute to discussions in
cultural sociology about beliefs and their
stability.},
Doi = {10.1177/01902725241228529},
Key = {fds376112}
}
@article{fds361388,
Author = {Kroska, A and Powell, B and Rogers, KB and Smith-Lovin,
L},
Title = {Affect Control Theories: A Double Special Issue in Honor of
David R. Heise},
Journal = {American Behavioral Scientist},
Volume = {67},
Number = {1},
Pages = {3-11},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1177/00027642211066044},
Abstract = {We introduce this two-part special issue that celebrates
David Heise and his pathbreaking theories: affect control
theory (ACT), affect control theory of the self (ACTS), and
affect control theory of institutions (ACTI). These
interlocking, multi-level, mathematically based theories
explain a range of social processes, including impression
formation, social interaction, trait and mood attributions,
emotional experiences, emotion management, and identity
adoption, and they do so in multiple languages and cultures.
The 15 articles in this two-part issue test, apply, and
develop the theories in new and innovative ways. After
briefly summarizing each theory and Bayesian affect control
theory (BayesACT), we highlight the key findings from each
of the articles that follow.},
Doi = {10.1177/00027642211066044},
Key = {fds361388}
}
@article{fds362447,
Author = {Quinn, JM and Freeland, RE and Rogers, KB and Hoey, J and Smith-Lovin,
L},
Title = {How Cultural Meanings of Occupations in the U.S. Changed
During the Covid-19 Pandemic.},
Journal = {The American behavioral scientist},
Volume = {67},
Number = {1},
Pages = {125-147},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1177/00027642211066041},
Abstract = {Social research highlights the stability of cultural
beliefs, broadly arguing that population-level changes are
uncommon and mostly explained by cohort replacement rather
than individual-level change. We find evidence suggesting
that cultural change may also occur rapidly in response to
an economically and socially transformative period. Using
data collected just before and after the outbreak of
Covid-19 in the U.S., we explore whether cultural beliefs
about essential and non-essential occupations are dynamic in
the face of an exogenous social and economic shock. Using a
sample of respondents whose characteristics match the U.S.
Census on sex, age, and race/ethnicity, we fielded surveys
measuring cultural beliefs about 85 essential and
non-essential occupations using the evaluation, potency, and
activity (EPA) dimensions from the Affect Control Theory
paradigm. We expected that EPA ratings of essential work
identities would increase due to positive media coverage of
essential occupations as indispensable and often selfless
roles in the pandemic, while EPA ratings of non-essential
identities would decline. Our findings show patterns that
are both clear and inconsistent with our predictions. For
both essential and non-essential occupations, almost all
statistically significant changes in mean evaluation and
potency were negative; activity showed relatively little
change. Changes in evaluation scores were more negative for
non-essential occupations than essential occupations.
Results suggest that pervasive and persistent exogenous
events are worth investigating as potential sources of
episodic cultural belief change.},
Doi = {10.1177/00027642211066041},
Key = {fds362447}
}
%% Smoski, Moria J.
@article{fds372227,
Author = {Darrow, SM and Pizzagalli, DA and Smoski, M and Mathew, SJ and Nurnberger, J and Lisanby, SH and Iosifescu, D and Murrough, JW and Yang, H and Weiner, RD and Sanacora, G and Keefe, RSE and Song, A and Goodman, W and Whitton, AE and Potter, WZ and Krystal,
AD},
Title = {Using latent profile analyses to classify subjects with
anhedonia based on reward-related measures obtained in the
FAST-MAS study.},
Journal = {J Affect Disord},
Volume = {339},
Pages = {584-592},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1016/j.jad.2023.07.081},
Abstract = {BACKGROUND: Growing evidence indicates that anhedonia is a
multifaceted construct. This study examined the possibility
of identifying subgroups of people with anhedonia using
multiple reward-related measures to provide greater
understanding the Research Domain Criteria's Positive
Valence Systems Domain and pathways for developing
treatments. METHODS: Latent profile analysis of baseline
data from a study that examined the effects of a novel kappa
opioid receptor (KOR) antagonist drug on measures and
biomarkers associated with anhedonia was used to identify
subgroups. Measures included ventral striatal activation
during the Monetary Incentive Delay task, response bias in
the Probabilistic Reward Task, reward valuation scores from
the Effort-Expenditure for Rewards Task, and scores from
reward-related self-report measures. RESULTS: Two subgroups
were identified, which differed on self-report measures of
reward. Participants in the subgroup reporting more
anhedonia also reported more depression and had greater
illness severity and functional impairments. Graphs of
change with treatment showed a trend for the less severe
subgroup to demonstrate higher response to KOR antagonist
treatment on the neuroimaging measure, probabilistic reward
task, and ratings of functioning; the subgroup with greater
severity showed a trend for higher treatment response on
reward-related self-report measures. LIMITATIONS: The main
limitations include the small sample size and exploratory
nature of analyses. CONCLUSIONS: Evidence of possible
dissociation between self-reported measures of anhedonia and
other measures with respect to treatment response emerged.
These results highlight the importance for future research
to consider severity of self-reported reward-related
deficits and how the relationship across measurement methods
may vary with severity.},
Doi = {10.1016/j.jad.2023.07.081},
Key = {fds372227}
}
@article{fds371655,
Author = {Schuette, SA and Andrade, FC and Woodward, JT and Smoski,
MJ},
Title = {Identifying modifiable factors associated with psychological
health in women experiencing infertility.},
Journal = {J Health Psychol},
Volume = {28},
Number = {12},
Pages = {1143-1156},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1177/13591053231185549},
Abstract = {This study assessed the relationship between modifiable
psychological variables and depression, anxiety, and
posttraumatic growth in women experiencing infertility. U.S.
women (N = 457) who identified as experiencing infertility
completed standardized self-report measures of mindfulness,
self-compassion, positive affect, intolerance of
uncertainty, relationship satisfaction, experiential
avoidance, depression, anxiety, and posttraumatic growth.
Clinical and demographic characteristics (age, duration
trying to conceive, miscarriage, and childlessness) did not
predict depression or anxiety. Lower positive affect and
higher experiential avoidance were associated with
depression and anxiety. Lower self-compassion was associated
with depression; higher intolerance of uncertainty was
associated with anxiety. There were indirect effects of
mindfulness on anxiety and depression via these variables.
Future research should explore whether intervening on these
factors reduces depressive and anxiety symptoms. Promoting
mindfulness may have beneficial effects on symptoms via its
downstream effects on multiple coping variables.
Counterintuitively, posttraumatic growth was associated with
higher intolerance of uncertainty and experiential
avoidance.},
Doi = {10.1177/13591053231185549},
Key = {fds371655}
}
@article{fds371266,
Author = {Phillips, RD and Walsh, EC and Zürcher, NR and Lalush, DS and Kinard,
JL and Tseng, C-E and Cernasov, PM and Kan, D and Cummings, K and Kelley,
L and Campbell, D and Dillon, DG and Pizzagalli, DA and Izquierdo-Garcia, D and Hooker, JM and Smoski, MJ and Dichter,
GS},
Title = {Striatal dopamine in anhedonia: A simultaneous
[11C]raclopride positron emission tomography and functional
magnetic resonance imaging investigation.},
Journal = {Psychiatry Res Neuroimaging},
Volume = {333},
Pages = {111660},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1016/j.pscychresns.2023.111660},
Abstract = {BACKGROUND: Anhedonia is hypothesized to be associated with
blunted mesocorticolimbic dopamine (DA) functioning in
samples with major depressive disorder. The purpose of this
study was to examine linkages between striatal DA, reward
circuitry functioning, anhedonia, and, in an exploratory
fashion, self-reported stress, in a transdiagnostic
anhedonic sample. METHODS: Participants with (n = 25) and
without (n = 12) clinically impairing anhedonia completed
a reward-processing task during simultaneous positron
emission tomography and magnetic resonance (PET-MR) imaging
with [11C]raclopride, a DA D2/D3 receptor antagonist that
selectively binds to striatal DA receptors. RESULTS:
Relative to controls, the anhedonia group exhibited
decreased task-related DA release in the left putamen,
caudate, and nucleus accumbens and right putamen and
pallidum. There were no group differences in task-related
brain activation (fMRI) during reward processing after
correcting for multiple comparisons. General functional
connectivity (GFC) findings revealed blunted fMRI
connectivity between PET-derived striatal seeds and target
regions in the anhedonia group. Associations were identified
between anhedonia severity and the magnitude of task-related
DA release to rewards in the left putamen, but not
mesocorticolimbic GFC. CONCLUSIONS: Results provide evidence
for reduced striatal DA functioning during reward processing
and blunted mesocorticolimbic network functional
connectivity in a transdiagnostic sample with clinically
significant anhedonia.},
Doi = {10.1016/j.pscychresns.2023.111660},
Key = {fds371266}
}
@article{fds370628,
Author = {Cernasov, PM and Kinard, JL and Walsh, E and Kelley, L and Phillips, R and Pisoni, A and Arnold, M and Lowery, SC and Ammirato, M and Nagy, GA and Oliver, JA and Haworth, K and Daughters, SB and Dichter, GS and Smoski,
M},
Title = {Parsing within & between-person dynamics of therapy homework
completion and clinical symptoms in two cognitive behavioral
treatments for adults with anhedonia.},
Journal = {Behav Res Ther},
Volume = {166},
Pages = {104322},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1016/j.brat.2023.104322},
Abstract = {OBJECTIVE: Homework is a key theoretical component of
cognitive-behavioral therapies, however, the effects of
homework on clinical outcomes have largely been evaluated
between-persons rather than within-persons. METHODS: The
effects of homework completion on treatment response were
examined in a randomized trial comparing Behavioral
Activation Treatment for Anhedonia (BATA, n = 38), a novel
psychotherapy, to Mindfulness-Based Cognitive Therapy (MBCT,
n=35). The primary endpoint was consummatory reward
sensitivity, measured weekly by the Snaith Hamilton Pleasure
Scale (SHAPS), up to 15 weeks. Multilevel models evaluated
change in SHAPS scores over time and the effects of
clinician-reported and participant-reported homework.
RESULTS: BATA and MBCT resulted in significant, equivalent
reductions in SHAPS scores. Unexpectedly, participants who
completed greater mean total amounts of homework did not
improve at a faster rate (i.e., no between-person effect).
However, sessions with greater than average
participant-reported homework completion were associated
with greater than average reductions in SHAPS scores (i.e.,
a within-person effect). For clinician-reported homework,
this effect was only evident within the BATA condition.
CONCLUSION: This study shows psychotherapy homework
completion relates to symptomatic improvement in
cognitive-behavioral treatments for anhedonia when
session-to-session changes are examined within-person. On
the contrary, we found no evidence that total homework
completion predicted greater improvements between-person.
When possible, psychotherapy researchers should evaluate
their constructs of interest across multiple sessions (not
just pre/post) to allow more direct tests of hypotheses
predicted by theoretical models of individual change
processes.},
Doi = {10.1016/j.brat.2023.104322},
Key = {fds370628}
}
@article{fds370314,
Author = {Phillips, R and Walsh, E and Jensen, T and Nagy, G and Kinard, J and Cernasov, P and Smoski, M and Dichter, G},
Title = {Longitudinal associations between perceived stress and
anhedonia during psychotherapy.},
Journal = {J Affect Disord},
Volume = {330},
Pages = {206-213},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1016/j.jad.2023.03.011},
Abstract = {BACKGROUND: Chronic stress alters reward sensitivity and
contributes to the emergence of anhedonia. In clinical
samples, the perception of stress is a strong predictor of
anhedonia. While there is substantial evidence demonstrating
psychotherapy reduces perceived stress, little is known
regarding the effects of treatment-related decreases in
perceived stress on anhedonia. METHODS: The current study
investigated reciprocal relations between perceived stress
and anhedonia using a cross-lagged panel model approach in a
15-week clinical trial examining the effects of Behavioral
Activation Treatment for Anhedonia (BATA), a novel
psychotherapy to treat anhedonia, compared to a
Mindfulness-Based Cognitive Therapy (MBCT) comparison
intervention (ClinicalTrials.gov Identifiers NCT02874534 and
NCT04036136). RESULTS: Treatment completers (n = 72)
experienced significant reductions in anhedonia
(M = -8.94, SD = 5.66) on the Snaith-Hamilton Pleasure
Scale (t(71) = 13.39, p < .0001), and significant
reductions in perceived stress (M = -3.71, SD = 3.88) on
the Perceived Stress Scale (t(71) = 8.11, p < .0001)
following treatment. Across all treatment-seeking
participants (n = 87), a longitudinal autoregressive
cross-lagged model revealed significant paths showing that
higher levels of perceived stress at treatment Week 1
predicted reductions in anhedonia at treatment Week 4; lower
levels of perceived stress at Week 8 predicted reductions in
anhedonia at Week 12. Anhedonia did not significantly
predict perceived stress at any stage of treatment.
CONCLUSIONS: This study showed specific timing and
directional effects of perceived stress on anhedonia during
psychotherapy treatment. Individuals with relatively high
perceived stress at the start of treatment were more likely
to report relatively lower anhedonia a few weeks into
treatment. At mid-treatment, individuals with low perceived
stress were more likely to report lower anhedonia towards
the end of treatment. These results demonstrate that early
treatment components reduce perceived stress, thus allowing
for downstream changes in hedonic functioning during
mid-late treatment. The findings presented here suggest it
will be critically important for future clinical trials
evaluating novel interventions for anhedonia to measure
stress levels repeatedly, as an important mechanism of
change. TRIAL NAME: Development of a Novel Transdiagnostic
Intervention for Anhedonia - R61 Phase. TRIAL URL:
https://clinicaltrials.gov/ct2/show/NCT02874534. TRIAL
REGISTRATION NUMBER: NCT02874534.},
Doi = {10.1016/j.jad.2023.03.011},
Key = {fds370314}
}
%% Sommer, Marc A.
@article{fds371675,
Author = {Subramanian, D and Pearson, JM and Sommer, MA},
Title = {Bayesian and Discriminative Models for Active Visual
Perception across Saccades.},
Journal = {eNeuro},
Volume = {10},
Number = {7},
Pages = {ENEURO.0403-ENEU22.2023},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1523/ENEURO.0403-22.2023},
Abstract = {The brain interprets sensory inputs to guide behavior, but
behavior itself disrupts sensory inputs. Perceiving a
coherent world while acting in it constitutes active
perception. For example, saccadic eye movements displace
visual images on the retina and yet the brain perceives
visual stability. Because this percept of visual stability
has been shown to be influenced by prior expectations, we
tested the hypothesis that it is Bayesian. The key
prediction was that priors would be used more as sensory
uncertainty increases. Humans and rhesus macaques reported
whether an image moved during saccades. We manipulated both
prior expectations and levels of sensory uncertainty. All
psychophysical data were compared with the predictions of
Bayesian ideal observer models. We found that humans were
Bayesian for continuous judgments. For categorical
judgments, however, they were anti-Bayesian: they used their
priors less with greater uncertainty. We studied this
categorical result further in macaques. The animals'
judgments were similarly anti-Bayesian for sensory
uncertainty caused by external, image noise, but Bayesian
for uncertainty due to internal, motor-driven noise. A
discriminative learning model explained the anti-Bayesian
effects. We conclude that active vision uses both Bayesian
and discriminative models depending on task requirements
(continuous vs categorical) and the source of uncertainty
(image noise vs motor-driven noise). In the context of
previous knowledge about the saccadic system, our results
provide an example of how the comparative analysis of
Bayesian versus non-Bayesian models of perception offers
novel insights into underlying neural organization.},
Doi = {10.1523/ENEURO.0403-22.2023},
Key = {fds371675}
}
@article{fds369379,
Author = {Daw, TB and El-Nahal, HG and Basso, MA and Jun, EJ and Bautista, AR and Samulski, RJ and Sommer, MA and Bohlen, MO},
Title = {Direct Comparison of Epifluorescence and Immunostaining for
Assessing Viral Mediated Gene Expression in the Primate
Brain.},
Journal = {Human gene therapy},
Volume = {34},
Number = {5-6},
Pages = {228-246},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1089/hum.2022.194},
Abstract = {Viral vector technologies are commonly used in neuroscience
research to understand and manipulate neural circuits, but
successful applications of these technologies in non-human
primate models have been inconsistent. An essential
component to improve these technologies is an impartial and
accurate assessment of the effectiveness of different viral
constructs in the primate brain. We tested a diverse array
of viral vectors delivered to the brain and extraocular
muscles of macaques and compared three methods for
histological assessment of viral-mediated fluorescent
transgene expression: epifluorescence (Epi),
immunofluorescence (IF), and immunohistochemistry (IHC).
Importantly, IF and IHC identified a greater number of
transduced neurons compared to Epi. Furthermore, IF and IHC
reliably provided enhanced visualization of transgene in
most cellular compartments (<i>i.e.</i>, dendritic, axonal,
and terminal fields), whereas the degree of labeling
provided by Epi was inconsistent and predominantly
restricted to somas and apical dendrites. Because Epi
signals are unamplified (in contrast to IF and IHC), Epi may
provide a more veridical assessment for the amount of
accumulated transgene and, thus, the potential to
chemogenetically or optogenetically manipulate neuronal
activity. The comparatively weak Epi signals suggest that
the current generations of viral constructs, regardless of
delivered transgene, are not optimized for primates. This
reinforces an emerging viewpoint that viral vectors tailored
for the primate brain are necessary for basic research and
human gene therapy.},
Doi = {10.1089/hum.2022.194},
Key = {fds369379}
}
%% Staddon, John E.
@misc{fds376836,
Author = {Staddon, J},
Title = {Summing Up},
Pages = {189-197},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-16},
Doi = {10.4324/9781032683874-16},
Key = {fds376836}
}
@misc{fds376843,
Author = {Staddon, J},
Title = {Science and Diversity},
Pages = {96-102},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-8},
Doi = {10.4324/9781032683874-8},
Key = {fds376843}
}
@misc{fds376844,
Author = {Staddon, J},
Title = {The Object of Inquiry Problem},
Pages = {159-165},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-13},
Doi = {10.4324/9781032683874-13},
Key = {fds376844}
}
@misc{fds376845,
Author = {Staddon, J},
Title = {Science and AI},
Pages = {89-95},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-7},
Doi = {10.4324/9781032683874-7},
Key = {fds376845}
}
@misc{fds376846,
Author = {Staddon, J},
Title = {Null Hypothesis Statistical Testing},
Pages = {44-53},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-4},
Doi = {10.4324/9781032683874-4},
Key = {fds376846}
}
@misc{fds376847,
Author = {Staddon, J},
Title = {Efficient Markets, I},
Pages = {166-175},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-14},
Doi = {10.4324/9781032683874-14},
Key = {fds376847}
}
@misc{fds376848,
Author = {Staddon, J},
Title = {What Is Science?},
Pages = {1-10},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-1},
Doi = {10.4324/9781032683874-1},
Key = {fds376848}
}
@misc{fds376849,
Author = {Staddon, J},
Title = {Behavioral Economics},
Pages = {135-147},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-11},
Doi = {10.4324/9781032683874-11},
Key = {fds376849}
}
@misc{fds376850,
Author = {Staddon, J},
Title = {Models and Incentives},
Pages = {54-68},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-5},
Doi = {10.4324/9781032683874-5},
Key = {fds376850}
}
@misc{fds376851,
Author = {Staddon, J},
Title = {Economics and Equilibria},
Pages = {111-134},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-10},
Doi = {10.4324/9781032683874-10},
Key = {fds376851}
}
@misc{fds376837,
Author = {Staddon, J},
Title = {Social Science},
Pages = {69-88},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-6},
Doi = {10.4324/9781032683874-6},
Key = {fds376837}
}
@misc{fds376838,
Author = {Staddon, J},
Title = {Some Science History},
Pages = {11-30},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-2},
Doi = {10.4324/9781032683874-2},
Key = {fds376838}
}
@misc{fds376839,
Author = {Staddon, J},
Title = {Social Science},
Pages = {103-110},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-9},
Doi = {10.4324/9781032683874-9},
Key = {fds376839}
}
@misc{fds376840,
Author = {Staddon, J},
Title = {Animal Economics},
Pages = {148-158},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-12},
Doi = {10.4324/9781032683874-12},
Key = {fds376840}
}
@misc{fds376841,
Author = {Staddon, J},
Title = {Experiment},
Pages = {31-43},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-3},
Doi = {10.4324/9781032683874-3},
Key = {fds376841}
}
@misc{fds376842,
Author = {Staddon, J},
Title = {Efficient Markets, II Event Studies and the
CAPM},
Pages = {176-188},
Booktitle = {Scientific Method},
Publisher = {Routledge},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.4324/9781032683874-15},
Doi = {10.4324/9781032683874-15},
Key = {fds376842}
}
@article{fds373392,
Author = {Staddon, J},
Title = {Diverse Identities are Irrelevant to Science},
Journal = {Academic Questions},
Volume = {36},
Number = {2},
Pages = {43-46},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.51845/36.2.8},
Doi = {10.51845/36.2.8},
Key = {fds373392}
}
@misc{fds372779,
Author = {Staddon, J},
Title = {Ideological Corruption of Science: Is the Right Always
Wrong?},
Pages = {327-341},
Booktitle = {The Palgrave Handbook of Left-Wing Extremism, Volume
2},
Publisher = {Springer Nature Switzerland},
Year = {2023},
ISBN = {9783031362675},
url = {http://dx.doi.org/10.1007/978-3-031-36268-2_18},
Doi = {10.1007/978-3-031-36268-2_18},
Key = {fds372779}
}
%% Strauman, Timothy J.
@article{fds371645,
Author = {Sharp, C and Kaplan, RM and Strauman, TJ},
Title = {The Use of Ontologies to Accelerate the Behavioral Sciences:
Promises and Challenges},
Journal = {Current Directions in Psychological Science},
Volume = {32},
Number = {5},
Pages = {418-426},
Publisher = {SAGE Publications},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1177/09637214231183917},
Abstract = {Behavioral scientists produce a vast amount of research
every year yet struggle to produce cumulative knowledge that
is easily translated in applied settings. This article
summarizes a National Academies of Sciences, Engineering,
and Medicine consensus report on the development and use of
ontologies to accelerate the behavioral sciences. The report
examines key challenges in the behavioral and psychological
sciences motivating an evaluation of ontology use and
development in the behavioral sciences. The advantages of
ontologies, including enhanced organization and retrieval of
research evidence, improved scientific communication,
reduction of duplication, and enhanced scientific
replicability, are highlighted. Challenges that may impede
the development and use of ontologies in the behavioral
sciences are also considered. The article concludes with
future directions for fulfilling the promise of ontologies
to accelerate the behavioral and psychological
sciences.},
Doi = {10.1177/09637214231183917},
Key = {fds371645}
}
@article{fds372293,
Author = {Oyesanya, TO and Loflin, C and You, H and Myers, J and Kandel, M and Johnson, K and Strauman, T and Hawes, J and Byom, L and Gonzalez-Guarda,
R and Van Houtven and C and Agarwal, S and Prvu Bettger,
J},
Title = {The BETTER Traumatic Brain Injury Transitional Care
Intervention: A Feasibility Study.},
Journal = {West J Nurs Res},
Volume = {45},
Number = {10},
Pages = {902-912},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1177/01939459231189786},
Abstract = {This study aimed to investigate the feasibility,
acceptability, and clinical outcome measures of BETTER
(Brain Injury Education, Training, and Therapy to Enhance
Recovery), a culturally tailored traumatic brain injury
(TBI) transitional care intervention, among diverse younger
adult patients with TBI (age 18-64) and their caregivers.
Trained clinical interventionists addressed patient/family
needs; established goals; coordinated post-hospital care and
resources; and provided patient/family training on self- and
family-management coping skills. Fifteen dyads enrolled (N =
31, 15 patients, 16 caregivers). All completed baseline
data; 74.2% (n = 23; 10 patients, 13 caregivers) completed
8-week data; 83.8% (n = 26; 13 each) completed 16-week data.
Approximately 38% (n = 12, 3 patients, 9 caregivers)
completed acceptability data, showing positive experiences
(mean = 9.25, range 0-10; SD = 2.01). Overall and mental
quality of life (QOL) scores did not differ over time but
physical QOL scores did improve over time (baseline: 30.3, 8
weeks: 46.5, 16 weeks: 61.6; p = 0.0056), which was
considered to be a suitable outcome measure for a future
trial. BETTER is a promising intervention with implications
to improve TBI care standards. Research is needed to
determine efficacy in a randomized trial.},
Doi = {10.1177/01939459231189786},
Key = {fds372293}
}
@article{fds370368,
Author = {Strauman, TJ and Hariri, AR},
Title = {Revising a Self-Regulation Phenotype for Depression Through
Individual Differences in Macroscale Brain
Organization.},
Journal = {Current directions in psychological science},
Volume = {32},
Number = {4},
Pages = {267-275},
Publisher = {SAGE Publications},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1177/09637214221149742},
Abstract = {<i>Self-regulation</i> denotes the processes by which people
initiate, maintain, and control their own thoughts,
behaviors, or emotions to produce a desired outcome or avoid
an undesired outcome. Self-regulation brings the influence
of distal factors such as biology, temperament, and
socialization history onto cognition, motivation, and
behavior. Dysfunction in self-regulation represents a
contributory causal factor for psychopathology. Accordingly,
we previously proposed a risk phenotype model for depression
drawing from regulatory focus theory and traditional
task-based fMRI studies. In this article, we revise and
expand our risk phenotype model using insights from new
methodologies allowing quantification of individual
differences in task-free macroscale brain organization. We
offer a set of hypotheses as examples of how examination of
intrinsic macroscale brain organization can extend and
enrich investigations of self-regulation and depression. In
doing so, we hope to promote a useful heuristic for model
development and for identifying transdiagnostic risk
phenotypes in psychopathology.},
Doi = {10.1177/09637214221149742},
Key = {fds370368}
}
@article{fds370879,
Author = {Oyesanya, TO and Ibemere, SO and Loflin, C and McReynolds, V and Anaya,
B and Huang, M and Gonzalez-Guarda, R and Strauman, TJ and Prvu Bettger,
J},
Title = {"If you respect me, you are respecting my culture": methods
and recommendations for personalizing a TBI transitional
care intervention.},
Journal = {Brain Inj},
Volume = {37},
Number = {8},
Pages = {746-757},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1080/02699052.2023.2208881},
Abstract = {OBJECTIVE: Despite research, national legislation, and
clinical guidelines supporting transitional care, there is
minimal benefit from existing transitional care
interventions for racial/ethnic minorities with traumatic
brain injury (TBI) discharged home from acute hospital care.
Existing TBI transitional care interventions are not
tailored to address the needs/preferences of patients from
various racial/ethnic minority groups. The purpose of this
study was to describe use of personalization to tailor a TBI
transitional care intervention for various racial/ethnic
groups. DESIGN: Following preliminary intervention manual
development, a qualitative descriptive study was conducted
using eight focus groups with 40 English-and
Spanish-speaking participants (12 patients, 12 caregivers,
and 16 providers). RESULTS: Three personalization-related
themes emerged: 1) what is important to me, 2) finding
someone to deliver the intervention who can adapt to my
needs, and 3) respect over culture. Findings informed
personalization strategies within our final manual.
CONCLUSIONS: We recommend researchers who wish to use
personalization to tailor interventions to consider: 1)
allowing stakeholders to dictate what is most important and
2) implementing an iterative intervention development
process with input from diverse stakeholders. Findings have
implications for informing the development of transitional
care interventions to increase the likelihood that
interventions are inclusive of needs and preferences of
various races/ethnicities.},
Doi = {10.1080/02699052.2023.2208881},
Key = {fds370879}
}
@article{fds369949,
Author = {Davis, SW and Beynel, L and Neacsiu, AD and Luber, BM and Bernhardt, E and Lisanby, SH and Strauman, TJ},
Title = {Network-level dynamics underlying a combined rTMS and
psychotherapy treatment for major depressive disorder: An
exploratory network analysis.},
Journal = {Int J Clin Health Psychol},
Volume = {23},
Number = {4},
Pages = {100382},
Year = {2023},
url = {http://dx.doi.org/10.1016/j.ijchp.2023.100382},
Abstract = {BACKGROUND: Despite the growing use of repetitive
transcranial magnetic stimulation (rTMS) as a treatment for
depression, there is a limited understanding of the
mechanisms of action and how potential treatment-related
brain changes help to characterize treatment response. To
address this gap in understanding we investigated the
effects of an approach combining rTMS with simultaneous
psychotherapy on global functional connectivity. METHOD: We
compared task-related functional connectomes based on an
idiographic goal priming task tied to emotional regulation
acquired before and after simultaneous rTMS/psychotherapy
treatment for patients with major depressive disorders and
compared these changes to normative connectivity patterns
from a set of healthy volunteers (HV) performing the same
task. RESULTS: At baseline, compared to HVs, patients
demonstrated hyperconnectivity of the DMN, cerebellum and
limbic system, and hypoconnectivity of the fronto-parietal
dorsal-attention network and visual cortex. Simultaneous
rTMS/psychotherapy helped to normalize these differences,
which were reduced after treatment. This finding suggests
that the rTMS/therapy treatment regularizes connectivity
patterns in both hyperactive and hypoactive brain networks.
CONCLUSIONS: These results help to link treatment to a
comprehensive model of the neurocircuitry underlying
depression and pave the way for future studies using
network-guided principles to significantly improve rTMS
efficacy for depression.},
Doi = {10.1016/j.ijchp.2023.100382},
Key = {fds369949}
}
@article{fds374569,
Author = {Smith, PJ and Whitson, HE and Merwin, RM and O'Hayer, CV and Strauman,
TJ},
Title = {Engineering Virtuous health habits using Emotion and
Neurocognition: Flexibility for Lifestyle Optimization and
Weight management (EVEN FLOW).},
Journal = {Front Aging Neurosci},
Volume = {15},
Pages = {1256430},
Year = {2023},
url = {http://dx.doi.org/10.3389/fnagi.2023.1256430},
Abstract = {Interventions to preserve functional independence in older
adults are critically needed to optimize 'successful aging'
among the large and increasing population of older adults in
the United States. For most aging adults, the management of
chronic diseases is the most common and impactful risk
factor for loss of functional independence. Chronic disease
management inherently involves the learning and adaptation
of new behaviors, such as adopting or modifying physical
activity habits and managing weight. Despite the importance
of chronic disease management in older adults, vanishingly
few individuals optimally manage their health behavior in
the service of chronic disease stabilization to preserve
functional independence. Contemporary conceptual models of
chronic disease management and health habit theory suggest
that this lack of optimal management may result from an
underappreciated distinction within the health behavior
literature: the behavioral domains critical for initiation
of new behaviors (Initiation Phase) are largely distinct
from those that facilitate their maintenance (Maintenance
Phase). Psychological factors, particularly experiential
acceptance and trait levels of openness are critical to
engagement with new health behaviors, willingness to make
difficult lifestyle changes, and the ability to tolerate
aversive affective responses in the process. Cognitive
factors, particularly executive function, are critical to
learning new skills, using them effectively across different
areas of life and contextual demands, and updating of skills
to facilitate behavioral maintenance. Emerging data
therefore suggests that individuals with greater executive
function are better able to sustain behavior changes, which
in turn protects against cognitive decline. In addition,
social and structural supports of behavior change serve a
critical buffering role across phases of behavior change.
The present review attempts to address these gaps by
proposing a novel biobehavioral intervention framework that
incorporates both individual-level and social support
system-level variables for the purpose of treatment
tailoring. Our intervention framework triangulates on the
central importance of self-regulatory functioning, proposing
that both cognitive and psychological mechanisms ultimately
influence an individuals' ability to engage in different
aspects of self-management (individual level) in the service
of maintaining independence. Importantly, the proposed
linkages of cognitive and affective functioning align with
emerging individual difference frameworks, suggesting that
lower levels of cognitive and/or psychological flexibility
represent an intermediate phenotype of risk. Individuals
exhibiting self-regulatory lapses either due to the
inability to regulate their emotional responses or due to
the presence of executive functioning impairments are
therefore the most likely to require assistance to preserve
functional independence. In addition, these vulnerabilities
will be more easily observable for individuals requiring
greater complexity of self-management behavioral demands
(e.g. complexity of medication regimen) and/or with lesser
social support. Our proposed framework also intuits several
distinct intervention pathways based on the profile of
self-regulatory behaviors: we propose that individuals with
intact affect regulation and impaired executive function
will preferentially respond to 'top-down' training
approaches (e.g., strategy and process work). Individuals
with intact executive function and impaired affect
regulation will respond to 'bottom-up' approaches (e.g.,
graded exposure). And individuals with impairments in both
may require treatments targeting caregiving or structural
supports, particularly in the context of elevated behavioral
demands.},
Doi = {10.3389/fnagi.2023.1256430},
Key = {fds374569}
}
%% Suarez, Edward C
@article{fds136724,
Title = {Suarez EC, Sherwood A, Hinderliter AL: Hostility and
adrenergic receptor responsiveness in high hostile men.
Journal Psychosomatic Research (In press).},
Key = {fds136724}
}
%% Swartzwelder, Harry S.
@article{fds376052,
Author = {Vore, AS and Marsland, P and Barney, TM and Varlinskaya, EI and Landin,
JD and Healey, KL and Kibble, S and Swartzwelder, HS and Chandler, LJ and Deak, T},
Title = {Adolescent intermittent ethanol (AIE) produces lasting,
sex-specific changes in rat body fat independent of changes
in white blood cell composition.},
Journal = {Front Physiol},
Volume = {15},
Pages = {1285376},
Year = {2024},
url = {http://dx.doi.org/10.3389/fphys.2024.1285376},
Abstract = {Early initiation of alcohol use during adolescence, and
adolescent binge drinking are risk factors for the
development of alcohol use disorder later in life.
Adolescence is a time of rapid sex-dependent neural,
physiological, and behavioral changes as well as a period of
heightened vulnerability to many effects of alcohol. The
goal of the present studies was to determine age-related
changes in blood (leukocyte populations) and body
composition across adolescence and early adulthood, and to
investigate whether adolescent intermittent ethanol (AIE)
exposure would alter the trajectory of adolescent
development on these broad physiological parameters. We
observed significant ontogenetic changes in leukocyte
populations that were mirrored by an age-related increase in
cytokine expression among mixed populations of circulating
leukocytes. Despite these developmental changes, AIE did not
significantly alter overall leukocyte numbers or cytokine
gene expression. However, AIE led to sex-specific changes in
body fat mass and fat percentage, with AIE-exposed male rats
showing significantly decreased fat levels and female rats
showing significantly increased fat levels relative to
controls. These changes suggest that while AIE may not alter
overall leukocyte levels, more complex phenotypic changes in
leukocyte populations could underlie previously reported
differences in cytokine expression. Coupled with long-term
shifts in adipocyte levels, this could have long-lasting
effects on innate immunity and the capacity of individuals
to respond to later immunological and physiological
threats.},
Doi = {10.3389/fphys.2024.1285376},
Key = {fds376052}
}
@article{fds375127,
Author = {Healey, K and Waters, RC and Knight, SG and Wandling, GM and Hall, NI and Jones, BN and Shobande, MJ and Melton, JG and Pandey, SC and Scott
Swartzwelder, H and Maldonado-Devincci, AM},
Title = {Adolescent intermittent ethanol exposure alters adult
exploratory and affective behaviors, and cerebellar Grin2b
expression in C57BL/6J mice.},
Journal = {Drug Alcohol Depend},
Volume = {253},
Pages = {111026},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1016/j.drugalcdep.2023.111026},
Abstract = {Binge drinking is one of the most common patterns (more than
90%) of alcohol consumption by young people. During
adolescence, the brain undergoes maturational changes that
influence behavioral control and affective behaviors, such
as cerebellar brain volume and function in adulthood. We
investigated long-term impacts of adolescent binge ethanol
exposure on affective and exploratory behaviors and
cerebellar gene expression in adult male and female mice.
Further, the cerebellum is increasingly recognized as a
brain region integrating a multitude of behaviors that span
from the traditional primary sensory-motor to affective
functions, such as anxiety and stress reactivity. Therefore,
we investigated the persistent effects of adolescent
intermittent ethanol (AIE) on exploratory and affective
behaviors and began to elucidate the role of the cerebellum
in these behaviors through excitatory signaling gene
expression. We exposed C57BL/6J mice to AIE or air (control)
vapor inhalation from postnatal day 28-42. After prolonged
abstinence (>34 days), in young adulthood (PND 77+) we
assessed behavior in the open field, light/dark, tail
suspension, and forced swim stress tests to determine
changes in affective behaviors including anxiety-like,
depressive-like, and stress reactivity behavior. Excitatory
signaling gene mRNA levels of fragile X messenger
ribonucleoprotein (FMR1), glutamate receptors (Grin2a,
Grin2b and Grm5) and excitatory synaptic markers (PSD-95 and
Eaat1) were measured in the cerebellum of adult control and
AIE-exposed mice. AIE-exposed mice showed decreased
exploratory behaviors in the open field test (OFT) where
both sexes show reduced ambulation, however only females
exhibited a reduction in rearing. Additionally, in the OFT,
AIE-exposed females also exhibited increased anxiety-like
behavior (entries to center zone). In the forced swim stress
test, AIE-exposed male mice, but not females, spent less
time immobile compared to their same-sex controls,
indicative of sex-specific changes in stress reactivity.
Male and female AIE-exposed mice showed increased Grin2b
(Glutamate Ionotropic Receptor NMDA Type Subunit 2B) mRNA
levels in the cerebellum compared to their same-sex
controls. Together, these data show that adolescent
binge-like ethanol exposure altered both exploratory and
affective behaviors in a sex-specific manner and modified
cerebellar Grin2b expression in adult mice. This indicates
the cerebellum may serve as an important brain region that
is susceptible to long-term molecular changes after
AIE.},
Doi = {10.1016/j.drugalcdep.2023.111026},
Key = {fds375127}
}
@article{fds371282,
Author = {Nwachukwu, KN and Mohammed, HE and Mebane, DR and Barber, AW and Swartzwelder, HS and Marshall, SA},
Title = {Acute and Chronic Ethanol Effects during Adolescence on
Neuroimmune Responses: Consequences and Potential
Pharmacologic Interventions.},
Journal = {Cells},
Volume = {12},
Number = {10},
Pages = {1423},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.3390/cells12101423},
Abstract = {Heavy ethanol consumption during adolescence has been linked
to neuroimmune response dysregulation and cognitive deficits
in the developing adolescent brain. During adolescence, the
brain is particularly susceptible to the pharmacological
effects of ethanol that are induced by acute and chronic
bouts of exposure. Numerous preclinical rodent model studies
have used different ethanol administration techniques, such
as intragastric gavage, self-administration, vapor,
intraperitoneal, and free access, and while most models
indicated proinflammatory neuroimmune responses in the
adolescent brain, there are various factors that appear to
influence this observation. This review synthesizes the most
recent findings of the effects of adolescent alcohol use on
toll-like receptors, cytokines, and chemokines, as well as
the activation of astrocytes and microglia with an emphasis
on differences associated with the duration of ethanol
exposure (acute vs. chronic), the amount of exposure (e.g.,
dose or blood ethanol concentrations), sex differences, and
the timing of the neuroimmune observation (immediate vs.
persistent). Finally, this review discusses new therapeutics
and interventions that may ameliorate the dysregulation of
neuroimmune maladaptations after ethanol
exposure.},
Doi = {10.3390/cells12101423},
Key = {fds371282}
}
@article{fds369168,
Author = {Healey, KL and Kibble, S and Dubester, K and Bell, A and Swartzwelder,
HS},
Title = {Adolescent intermittent ethanol exposure enhances adult
stress effects in male rats.},
Journal = {Pharmacol Biochem Behav},
Volume = {223},
Pages = {173513},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1016/j.pbb.2022.173513},
Abstract = {Binge patterns of alcohol use, prevalent among adolescents,
are associated with a higher probability of developing
alcohol use disorders (AUD) and other psychiatric disorders,
like anxiety and depression. Additionally, adverse life
events strongly predict AUD and other psychiatric disorders.
As such, the combined fields of stress and AUD have been
well established, and animal models indicate that both
binge-like alcohol exposure and stress exposure elevate
anxiety-like behaviors. However, few have investigated the
interaction of adolescent intermittent ethanol (AIE) and
adult stressors. We hypothesized that AIE would increase
vulnerability to restraint-induced stress (RS), manifested
as increased anxiety-like behavior. After AIE exposure, in
adulthood, animals were tested on forced swim (FST) and
saccharin preference (SP) and then exposed to either RS
(90 min/5 days) or home-cage control. Twenty-four hours
after the last RS session, animals began testing on the
elevated plus maze (EPM), and were re-tested on FST and SP.
A separate group of animals were sacrificed in adulthood
after AIE and RS, and brains were harvested for immunoblot
analysis of dorsal and ventral hippocampus. Consistent with
previous reports, AIE had no significant effect on closed
arm time in the EPM (anxiety-like behavior). However, in
male rats the interaction of AIE and adult RS increased time
spent in the closed arms. No effect was observed among
female animals. AIE and RS-specific alterations were found
in glial and synaptic markers (GLT-1, FMRP and PSD-95) in
male animals. These findings indicate AIE has sex-specific
effects on both SP and the interaction of AIE and adult RS,
which induces a propensity toward anxiety-like behavior in
males. Also, AIE produces persistent hippocampal deficits
that may interact with adult RS to cause increased
anxiety-like behaviors. Understanding the mechanisms behind
this AIE-induced increase in stress vulnerability may
provide insight into treatment and prevention strategies for
alcohol use disorders.},
Doi = {10.1016/j.pbb.2022.173513},
Key = {fds369168}
}
@article{fds372992,
Author = {Healey, KL and Marshall, SA and Grillo, WH and Swartzwelder,
HS},
Title = {Duke-NC centeral alcohol research & education (D-CARE) an
undergraduate multi-institution alcohol research training
program},
Journal = {ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH},
Volume = {47},
Pages = {466-467},
Year = {2023},
Key = {fds372992}
}
@article{fds372993,
Author = {Healey, KL and Bell, A and Marshall, SA and Swartzwelder,
HS},
Title = {Adolescent intermittent ethanol-induced effects on activity,
anxiety, memory & biological markers: Sex-specificity and
prevention with dietary choline},
Journal = {ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH},
Volume = {47},
Pages = {488-489},
Year = {2023},
Key = {fds372993}
}
@article{fds372994,
Author = {Nwachukwu, K and Nelson, J and Swartzwelder, HS and Marshall,
SA},
Title = {Donepezil reversal of alcohol-induced changes in hippocampal
astrocytic and neurogenic responses after adolescent
intermittent ethanol exposure},
Journal = {ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH},
Volume = {47},
Pages = {255-255},
Year = {2023},
Key = {fds372994}
}
%% Taylor, Morgan
@article{fds369955,
Author = {Chauhan, V and Visconti di Oleggio Castello and M and Taylor, M and Gobbini, MI},
Title = {Familiarity Facilitates Detection of Angry
Expressions.},
Journal = {Brain Sciences},
Volume = {13},
Number = {3},
Pages = {509},
Publisher = {MDPI AG},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.3390/brainsci13030509},
Abstract = {Personal familiarity facilitates rapid and optimized
detection of faces. In this study, we investigated whether
familiarity associated with faces can also facilitate the
detection of facial expressions. Models of face processing
propose that face identity and face expression detection are
mediated by distinct pathways. We used a visual search
paradigm to assess if facial expressions of emotion (anger
and happiness) were detected more rapidly when produced by
familiar as compared to unfamiliar faces. We found that
participants detected an angry expression 11% more
accurately and 135 ms faster when produced by familiar as
compared to unfamiliar faces while happy expressions were
detected with equivalent accuracies and at equivalent speeds
for familiar and unfamiliar faces. These results suggest
that detectors in the visual system dedicated to processing
features of angry expressions are optimized for familiar
faces.},
Doi = {10.3390/brainsci13030509},
Key = {fds369955}
}
@article{fds369075,
Author = {Sinclair, AH and Taylor, MK and Weitz, JS and Beckett, SJ and Samanez-Larkin, GR},
Title = {Reasons for Receiving or Not Receiving Bivalent COVID-19
Booster Vaccinations Among Adults - United States, November
1-December 10, 2022.},
Journal = {Mmwr. Morbidity and Mortality Weekly Report},
Volume = {72},
Number = {3},
Pages = {73-75},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.15585/mmwr.mm7203a5},
Abstract = {Bivalent COVID-19 booster vaccines, developed to protect
against both ancestral and Omicron BA.4/BA.5 variants, are
recommended to increase protection against SARS-CoV-2
infection and severe disease* (1,2). However, relatively few
eligible U.S. adults have received a bivalent booster dose
(3), and reasons for low coverage are unclear. An opt-in
Internet survey of 1,200 COVID-19-vaccinated U.S. adults was
conducted to assess reasons for receiving or not receiving a
bivalent booster dose. Participants could select multiple
reasons from a list of suggested reasons to report why they
had or had not received a bivalent booster dose. The most
common reasons cited for not receiving the bivalent booster
dose were lack of awareness of eligibility for vaccination
(23.2%) or of vaccine availability (19.3%), and perceived
immunity against infection (18.9%). After viewing
information about eligibility and availability, 67.8% of
participants who had not received the bivalent booster dose
indicated that they planned to do so; in a follow-up survey
1 month later, 28.6% of these participants reported having
received the dose. Among those who had planned to receive
the booster dose but had not yet done so, 82.6% still
intended to do so. Participants who had still not received
the booster dose most commonly reported being too busy to
get vaccinated (35.6%). To help increase bivalent booster
dose coverage, health care and public health professionals
should use evidence-based strategies to convey information
about booster vaccination recommendations and waning
immunity (4), while also working to increase convenient
access.},
Doi = {10.15585/mmwr.mm7203a5},
Key = {fds369075}
}
%% Thompson, Robert J.
@article{fds372910,
Author = {Thompson, RJ and Schmid, L and Mburi, M and Dowd, JE and Finkenstaedt-Quinn, SA and Shultz, GV and Gere, AR and Schiff, LA and Flash, P and Reynolds, JA},
Title = {Diversity of undergraduates in STEM courses: individual and
demographic differences in changes in self-efficacy,
epistemic beliefs, and intrapersonal attribute
profiles},
Journal = {Studies in Higher Education},
Volume = {49},
Number = {4},
Pages = {690-711},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1080/03075079.2023.2250385},
Abstract = {Across undergraduate STEM learning contexts in several
countries, students’ intrapersonal attributes of epistemic
beliefs, self-efficacy beliefs, intrinsic motivation, and
sense of identity have been found to influence learning and
to change in response to educational practices. However,
research can mask individual and demographic differences in
student's attributes that may moderate or mediate the
relationship between educational practices and learning
outcomes. We employed variable-centered and person-centered
methods to examine individual and demographic differences in
changes in students’ intrapersonal attributes and patterns
of interrelationship among attributes with a study sample of
students (N = 4,500) in 14 STEM undergraduate courses (8
biology, 4 chemistry, and 2 statistics) at three research
universities in the United States. Variable-centered
analyses revealed overall increases in students’ science
self-efficacy beliefs and epistemic beliefs even though
these outcomes were not intentionally targeted as learning
objectives. However, person-centered analyses indicated that
not all students experienced these gains. For example,
self-identified Asian/Pacific Islander and Black students
were more likely to be members of groups demonstrating a
decrease in science self-efficacy, whereas Asian/Pacific
Islander students and men were less likely to be members of
the subgroup with consistently evaluativist epistemic
beliefs and higher GPAs. Using latent profile analysis
(LPA), we identified five distinct student profiles that
reflected different patterns of interrelationship of
epistemic beliefs, science and writing self-efficacy
beliefs, and science identity. We discuss the implications
of these findings for educational practices, particularly
with regard to intentionally fostering diverse students’
self-efficacy, sense of identity, and adaptive epistemic
beliefs.},
Doi = {10.1080/03075079.2023.2250385},
Key = {fds372910}
}
%% Tomasello, Michael
@article{fds374401,
Author = {Winter Née Grocke and P and Tomasello, M},
Title = {From what I want to do to what we decided to do:
5-year-olds, but not 3-year-olds, honor their agreements
with peers.},
Journal = {Journal of experimental child psychology},
Volume = {239},
Pages = {105811},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1016/j.jecp.2023.105811},
Abstract = {Sometimes we have a personal preference but we agree with
others to follow a different course of action. In this
study, 3- and 5-year-old children (N = 160) expressed a
preference for playing a game one way and were then
confronted with peers who expressed a different preference.
The experimenter then either got the participants to agree
with the peers explicitly or just shrugged her shoulders and
moved on. The children were then left alone to play the game
unobserved. Only the older children stuck to their agreement
to play the game as the peers wished. These results suggest
that by 5 years of age children's sense of commitment to
agreements is strong enough to override their personal
preferences.},
Doi = {10.1016/j.jecp.2023.105811},
Key = {fds374401}
}
@article{fds374171,
Author = {Katz, T and Kushnir, T and Tomasello, M},
Title = {Children are eager to take credit for prosocial acts, and
cost affects this tendency.},
Journal = {Journal of experimental child psychology},
Volume = {237},
Pages = {105764},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1016/j.jecp.2023.105764},
Abstract = {We report two experiments on children's tendency to enhance
their reputations through communicative acts. In the
experiments, 4-year-olds (N = 120) had the opportunity to
inform a social partner that they had helped him in his
absence. In a first experiment, we pitted a prosocial act
("Let's help clean up for Doggie!") against an instrumental
act ("Let's move these out of our way"). Children in the
prosocial condition were quicker to inform their partner of
the act and more likely to protest when another individual
was given credit for it. In a second experiment, we
replicated the prosocial condition but with a new
manipulation: high-cost versus low-cost helping. We
manipulated both the language surrounding cost (i.e., "This
will be pretty tough to clean up" vs. "It will be really
easy to clean this up") and how difficult the task itself
was. As predicted, children in the high-cost condition were
quicker to inform their partner of the act and more likely
to take back credit for it. These results suggest that even
4-year-old children make active attempts to elicit positive
reputational judgments for their prosocial acts, with cost
as a moderating factor.},
Doi = {10.1016/j.jecp.2023.105764},
Key = {fds374171}
}
@article{fds374236,
Author = {Tomasello, M},
Title = {Differences in the Social Motivations and Emotions of Humans
and Other Great Apes.},
Journal = {Human nature (Hawthorne, N.Y.)},
Volume = {34},
Number = {4},
Pages = {588-604},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1007/s12110-023-09464-0},
Abstract = {Humans share with other mammals and primates many social
motivations and emotions, but they are also much more
cooperative than even their closest primate relatives. Here
I review recent comparative experiments and analyses that
illustrate humans' species-typical social motivations and
emotions for cooperation in comparison with those of other
great apes. These may be classified most generally as (i)
'you > me' (e.g., prosocial sympathy, informative and
pedagogical motives in communication); (ii) 'you = me'
(e.g., feelings of mutual respect, fairness, resentment);
(iii) 'we > me' (e.g., feelings of obligation and guilt);
and (iv) 'WE (in the group) > me' (e.g., in-group
loyalty and conformity to norms, shame, and many in-group
biases). The existence of these species-typical and
species-universal motivations and emotions provides
compelling evidence for the importance of cooperative
activities in the human species.},
Doi = {10.1007/s12110-023-09464-0},
Key = {fds374236}
}
@article{fds374400,
Author = {Vasil, J and Price, D and Tomasello, M},
Title = {Thought and language: Effects of group-mindedness on young
children's interpretation of exclusive we.},
Journal = {Child development},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1111/cdev.14049},
Abstract = {The current study investigated whether age-related changes
in the conceptualization of social groups influences
interpretation of the pronoun we. Sixty-four 2- and
4-year-olds (N = 29 female, 50 White-identifying) viewed
scenarios in which it was ambiguous how many puppets
performed an activity together. When asked who performed the
activity, a speaker puppet responded, "We did!" In one
condition, the speaker was near one and distant from another
puppet, implying a dyadic interpretation of we. In another
condition, the speaker was distant from both, thus pulling
for a group interpretation. In the former condition, 2- and
4-year-olds favored the dyadic interpretation. In the latter
condition, only 4-year-olds favored the group
interpretation. Age-related conceptual development "expands"
the set of conceivable plural person referents.},
Doi = {10.1111/cdev.14049},
Key = {fds374400}
}
@article{fds373982,
Author = {Wolf, W and Tomasello, M},
Title = {A Shared Intentionality Account of Uniquely Human Social
Bonding.},
Journal = {Perspectives on psychological science : a journal of the
Association for Psychological Science},
Pages = {17456916231201795},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1177/17456916231201795},
Abstract = {Many mechanisms of social bonding are common to all
primates, but humans seemingly have developed some that are
unique to the species. These involve various kinds of
interactive experiences-from taking a walk together to
having a conversation-whose common feature is the triadic
sharing of experience. Current theories of social bonding
have no explanation for why humans should have these unique
bonding mechanisms. Here we propose a shared intentionality
account of uniquely human social bonding. Humans evolved to
participate with others in unique forms of cooperative and
communicative activities that both depend on and create
shared experience. Sharing experience in these activities
causes partners to feel closer because it allows them to
assess their partner's cooperative competence and motivation
toward them and because the shared representations created
during such interactions make subsequent cooperative
interactions easier and more effective.},
Doi = {10.1177/17456916231201795},
Key = {fds373982}
}
@article{fds370890,
Author = {Vasil, J and Moore, C and Tomasello, M},
Title = {Thought and language: association of groupmindedness with
young English-speaking children’s production of
pronouns},
Journal = {First Language},
Volume = {43},
Number = {5},
Pages = {516-538},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1177/01427237231169398},
Abstract = {Shared intentionality theory posits that at age 3, children
expand their conception of plural agency to include 3- or
more-person groups. We sought to determine whether this
conceptual shift is detectable in children’s pronoun use.
We report the results of a series of Bayesian hierarchical
generative models fitted to 479 English-speaking
children’s first-person plural, first-person singular,
second-person, third-person plural, and third-person
singular pronouns. As a proportion of pronouns, children
used more first-person plural pronouns, only, after 3;0
compared to before. Additionally, children used more 1pp.
pronouns when their mothers used more 1pp. pronouns. As a
proportion of total utterances, all pronoun classes were
used more often as children aged. These findings suggest
that a shift in children’s social conceptualizations at
age 3 is reflected in their use of 1pp. pronouns.},
Doi = {10.1177/01427237231169398},
Key = {fds370890}
}
@article{fds370629,
Author = {Benozio, A and House, BR and Tomasello, M},
Title = {Apes reciprocate food positively and negatively.},
Journal = {Proceedings. Biological sciences},
Volume = {290},
Number = {1998},
Pages = {20222541},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1098/rspb.2022.2541},
Abstract = {Reciprocal food exchange is widespread in human societies
but not among great apes, who may view food mainly as a
target for competition. Understanding the similarities and
differences between great apes' and humans' willingness to
exchange food is important for our models regarding the
origins of uniquely human forms of cooperation. Here, we
demonstrate in-kind food exchanges in experimental settings
with great apes for the first time. The initial sample
consisted of 13 chimpanzees and 5 bonobos in the control
phases, and the test phases included 10 chimpanzees and 2
bonobos, compared with a sample of 48 human children aged 4
years. First, we replicated prior findings showing no
spontaneous food exchanges in great apes. Second, we
discovered that when apes believe that conspecifics have
'intentionally' transferred food to them, positive
reciprocal food exchanges (food-for-food) are not only
possible but reach the same levels as in young children
(approx. 75-80%). Third, we found that great apes engage in
negative reciprocal food exchanges (no-food for no-food) but
to a lower extent than children. This provides evidence for
reciprocal food exchange in great apes in experimental
settings and suggests that while a potential mechanism of
<i>fostering</i> cooperation (via positive reciprocal
exchanges) may be shared across species, a stabilizing
mechanism (via negative reciprocity) is not.},
Doi = {10.1098/rspb.2022.2541},
Key = {fds370629}
}
@article{fds368903,
Author = {Schäfer, M and B M Haun and D and Tomasello, M},
Title = {Children's consideration of collaboration and merit when
making sharing decisions in private.},
Journal = {Journal of experimental child psychology},
Volume = {228},
Pages = {105609},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1016/j.jecp.2022.105609},
Abstract = {Young children share equally when they acquire resources
through collaboration with a partner, yet it is unclear
whether they do so because in such contexts resources are
encountered as common and distributed in front of the
recipient or because collaboration promotes a sense of
work-based fairness. In the current studies, 5- and
8-year-old children from Germany (N = 193) acquired
resources either by working individually alongside or by
collaborating with a peer. After finding out that the
partner's container was empty, they decided in private
whether they wanted to donate some resources to the peer.
When both partners had worked with equal efforts (Study 1),
children shared more after collaboration than after
individual work. When one partner had worked with much more
effort than the other (Study 2), children shared more with a
harder-working partner than with a less-working partner
independently of whether they had collaborated or worked
individually. Younger children were more generous than older
children, in particular after collaboration. These findings
support the view that collaboration promotes a genuine sense
of fairness in young children, but they also indicate that
merit-based notions of fairness in the context of work may
develop independently of collaboration, at least by the
beginning of middle childhood and in Western
societies.},
Doi = {10.1016/j.jecp.2022.105609},
Key = {fds368903}
}
@article{fds367773,
Author = {Colle, L and Grosse, G and Behne, T and Tomasello,
M},
Title = {Just teasing! - Infants' and toddlers' understanding of
teasing interactions and its effect on social
bonding.},
Journal = {Cognition},
Volume = {231},
Pages = {105314},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1016/j.cognition.2022.105314},
Abstract = {The current study investigates infants' and toddlers'
understanding of teasing interactions and its effect on
subsequent social interactions. Teasing is a special kind of
social interaction due to its dual nature: It consists of a
slightly provocative contingent action accompanied by
positive ostensive emotional cues. Teasing thus presents an
especially interesting test case to inform us about young
children's abilities to deal with complex social intentions.
In a first experiment, we looked at 9-, 12-, and
18-month-old infants' ability to understand and
differentiate a teasing intention from a trying intention
and a refuse intention. We found that by 12 months of age,
infants react differently (gaze, reach) and by 18 months
they smile more in reaction to the Tease condition. In the
second experiment, we tested 13-, 20- and 30-month-old
children in closely matched purely playful and teasing
situations. We also investigated potential social effects of
teasing interactions on a subsequent affiliation sequence.
Twenty- and 30-month-old children smile more in the Teasing
than in the Play condition. For the 30-month-old toddlers,
additionally, number of laughs is much higher in the Tease
than in the Play condition. No effect on affiliation could
be found. Thus, from very early in development, infants and
toddlers are able to differentiate teasing from
superficially similar but serious behavior and from around
18 months of age they enjoy it more. Infants and toddlers
are able to process a complex social intention like teasing.
Findings are discussed regarding infant and toddler
intention understanding abilities.},
Doi = {10.1016/j.cognition.2022.105314},
Key = {fds367773}
}
@article{fds362755,
Author = {Hepach, R and Engelmann, JM and Herrmann, E and Gerdemann, SC and Tomasello, M},
Title = {Evidence for a developmental shift in the motivation
underlying helping in early childhood.},
Journal = {Developmental science},
Volume = {26},
Number = {1},
Pages = {e13253},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1111/desc.13253},
Abstract = {We investigated children's positive emotions as an indicator
of their underlying prosocial motivation. In Study 1, 2-,
and 5-year-old children (N = 64) could either help an
individual or watch as another person provided help.
Following the helping event and using depth sensor imaging,
we measured children's positive emotions through changes in
postural elevation. For 2-year-olds, helping the individual
and watching another person help was equally rewarding;
5-year-olds showed greater postural elevation after actively
helping. In Study 2, 5-year-olds' (N = 59) positive
emotions following helping were greater when an audience was
watching. Together, these results suggest that 2-year-old
children have an intrinsic concern that individuals be
helped whereas 5-year-old children have an additional,
strategic motivation to improve their reputation by
helping.},
Doi = {10.1111/desc.13253},
Key = {fds362755}
}
@article{fds365125,
Author = {Tomasello, M},
Title = {Social cognition and metacognition in great apes: a
theory.},
Journal = {Animal cognition},
Volume = {26},
Number = {1},
Pages = {25-35},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1007/s10071-022-01662-0},
Abstract = {Twenty-five years ago, at the founding of this journal,
there existed only a few conflicting findings about great
apes' social-cognitive skills (theory of mind). In the 2 ½
decades since, we have discovered that great apes understand
the goals, intentions, perceptions, and knowledge of others,
and they use this knowledge to their advantage in
competitive interactions. Twenty-five years ago there
existed basically no studies on great apes' metacognitive
skills. In the 2 ½ decades since, we have discovered that
great apes monitor their uncertainty and base their
decisions on that, or else decide to gather more information
to make better decisions. The current paper reviews the past
25 years of research on great ape social cognition and
metacognition and proposes a theory about how the two are
evolutionarily related.},
Doi = {10.1007/s10071-022-01662-0},
Key = {fds365125}
}
@article{fds371813,
Author = {Wolf, W and Thielhelm, J and Tomasello, M},
Title = {Five-year-old children show cooperative preferences for
faces with white sclera.},
Journal = {Journal of experimental child psychology},
Volume = {225},
Pages = {105532},
Year = {2023},
Month = {January},
url = {http://dx.doi.org/10.1016/j.jecp.2022.105532},
Abstract = {The cooperative eye hypothesis posits that human eye
morphology evolved to facilitate cooperation. Although it is
known that young children prefer stimuli with eyes that
contain white sclera, it is unknown whether white sclera
influences children's perception of a partner's
cooperativeness specifically. In the current studies, we
used an online methodology to present 5-year-old children
with moving three-dimensional face models in which facial
morphology was manipulated. Children found "alien" faces
with human eyes more cooperative than faces with dark sclera
(Study 2) but not faces with enlarged irises (Study 1). For
more human-like faces (Study 3), children found human eyes
more cooperative than either enlarged irises or dark sclera
and found faces with enlarged irises cuter (but not more
cooperative) than eyes with dark sclera. Together, these
results provide strong support for the cooperative eye
hypothesis.},
Doi = {10.1016/j.jecp.2022.105532},
Key = {fds371813}
}
@misc{fds371506,
Author = {Tomasello, M},
Title = {Having Intentions, Understanding Intentions, and
Understanding Communicative Intentions},
Pages = {63-75},
Booktitle = {Developing Theories of Intention: Social Understanding and
Self-Control},
Year = {2023},
Month = {January},
ISBN = {9780805831412},
url = {http://dx.doi.org/10.4324/9781003417927-5},
Abstract = {This chapter looks at a major cause and a major consequence
of the 9-month social-cognitive revolution; and both of
these also concern infant intentionality. It argues that
young children’s understanding of other persons as
intentional agents results in large part from newly emerging
forms of intentionality in their own sensory-motor actions.
The chapter explores young children’s understanding of a
special type of intention that emerges directly on the heels
of the 9-month revolution, namely, communicative intentions.
Intentional agents have goals and make active choices among
behavioral means for attaining those goals. Important,
intentional agents also make active choices about what they
pay attention to in pursuing those goals. ntentional agents
have goals and make active choices among behavioral means
for attaining those goals. Important, intentional agents
also make active choices about what they pay attention to in
pursuing those goals.},
Doi = {10.4324/9781003417927-5},
Key = {fds371506}
}
%% Van Cappellen, Patty
@article{fds372239,
Author = {Reece, GA and Van Tongeren and DR and Van Cappellen,
P},
Title = {Eternal outgroups: Afterlife beliefs predict
prejudice},
Journal = {Personality and Individual Differences},
Volume = {214},
Pages = {112352-112352},
Publisher = {Elsevier BV},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1016/j.paid.2023.112352},
Abstract = {People express prejudice toward ideologically dissimilar
groups. However, little research has explored (a) how
specific beliefs, such as afterlife beliefs, relate to
prejudice, (b) whether such beliefs can explain the known
association between religiosity and prejudice toward
value-threatening groups, and (c) the mechanisms through
which afterlife beliefs predict prejudice. We addressed
these questions by assessing individual differences in
religious, spiritual, and secular afterlife beliefs and
attitudes toward religious and political groups. Across four
studies (N = 3996 U.S. adults), we find evidence supporting
a group exclusion hypothesis: religious and secular
afterlife beliefs predict prejudice toward value-incongruent
groups (even after controlling for religiosity). We also
find some evidence that religious afterlife beliefs explain
the association between religiosity and prejudice against
value-threatening groups. Finally, we find moderate support
for an existential anxiety buffer hypothesis, wherein some
afterlife beliefs predict increased peace of mind, reduced
death anxiety, and in turn, reduced prejudice.},
Doi = {10.1016/j.paid.2023.112352},
Key = {fds372239}
}
@article{fds365925,
Author = {Van Cappellen and P and Edwards, ME and Shiota, MN},
Title = {Shades of expansiveness: Postural expression of dominance,
high-arousal positive affect, and warmth.},
Journal = {Emotion},
Volume = {23},
Number = {4},
Pages = {973-985},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1037/emo0001146},
Abstract = {In addition to the face, bodily posture plays an important
role in communicating affective states. Postural
expansion-how much space the body takes up-has been much
studied as expressing and signaling dominance and pride. The
present research aimed to expand research on the range of
affect dimensions and affect-laden personality
characteristics that are expressed via expansiveness,
investigating specific forms of expansiveness and their
interactions with other postural elements (e.g., arm
position). Using an innovative expression-production method,
Study 1 (<i>N</i> = 146) characterized full-body expressions
of dominance, joy, hope, and awe; results indicated joy is
communicated most expansively and suggested a signature arm
position for most feelings. Studies 2 and 3 (<i>N</i>s = 352
and 183) revealed that other postural features interact with
expansiveness to signal dominance (arms akimbo, head raised,
stability), as distinct from high-arousal positive affect
(arms high up, head raised) and warmth (arms high up, head
raised, instability). Together, this research adds needed
data on full-body expressions of positive affect states and
provides systematic analysis of different affective messages
and varieties of postural expansiveness. (PsycInfo Database
Record (c) 2023 APA, all rights reserved).},
Doi = {10.1037/emo0001146},
Key = {fds365925}
}
%% Weeks, Molly
@misc{fds376036,
Author = {Cerda-Smith, J and Yust, PKS and Weeks, MS and Asher, SR and Mulvey,
KL},
Title = {A Novel Approach for Evaluating a Schoolwide Antiracist
Curriculum Intervention},
Journal = {AERA Open},
Volume = {10},
Publisher = {SAGE Publications},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1177/23328584231223476},
Abstract = {This manuscript describes our effort to apply a novel
approach to understanding student outcomes associated with a
schoolwide antiracist intervention. We report a multimethod
quantitative approach to evaluate a 10-week antiracist
intervention designed and implemented by school staff by
examining patterns of student intervention engagement and
measures of key constructs that connect to antiracism,
psychological well-being, and school connectedness. Our
novel approach combines schoolwide surveys with smaller
samples of daily diary participants, documenting variation
in intervention engagement and examining postintervention
outcomes. Our findings are limited by high attrition rates,
small sample size, and data collection during the COVID-19
pandemic; however, our methods offer a promising
transferable approach to evaluate school-based antiracist
interventions by examining patterns and predictors of
intervention engagement, as well as daily fluctuations in
student experience throughout the intervention
period.},
Doi = {10.1177/23328584231223476},
Key = {fds376036}
}
@misc{fds371265,
Author = {Yust, PKS and Weeks, MS and Williams, GA and Asher,
SR},
Title = {Social relationship provisions and loneliness in school:
Child- and classroom-level effects.},
Journal = {Journal of school psychology},
Volume = {99},
Pages = {101218},
Publisher = {Elsevier BV},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1016/j.jsp.2023.05.001},
Abstract = {Building on social needs theory (Weiss, 1974), this study
introduces the construct of classroom provision richness and
examines the association between the exchange of social
provisions among children in classrooms and children's
feelings of loneliness in school. We examined the receipt of
provisions from reciprocally nominated friends versus
unilateral (one-sided) and non-friend classmates and
examined associations between social provisions and
loneliness at the child and classroom levels. Participants
were 998 third- through fifth-grade children (468 girls, 530
boys; 88.5% White) in 38 classrooms who indicated which
classmates they played with, helped, validated, and provided
opportunities for self-disclosure. In addition to the social
provisions nomination measure, children responded to (a) a
measure of loneliness that avoided content overlapping with
social provisions, (b) a rating-scale sociometric measure of
peer acceptance, and (c) a measure that asked them to
indicate which classmates engaged in prosocial, aggressive,
or withdrawn-type behaviors. Multilevel analyses indicated
that social provisions received from reciprocal friends and
from unilateral-received friends were associated with
children's feelings of loneliness in school. Furthermore, a
measure of the provision richness of classrooms moderated
the association between child-level provisions received and
feelings of loneliness, such that children who received
fewer provisions were less lonely in classrooms that were
more provision-rich. Classroom provision richness was also
associated with the general level of prosocial behavior and
peer acceptance in the classroom. Together, findings suggest
that efforts to foster the exchange of social provisions in
classrooms could reduce loneliness and facilitate a more
caring classroom environment.},
Doi = {10.1016/j.jsp.2023.05.001},
Key = {fds371265}
}
%% Weinfurt, Kevin P.
@article{fds376698,
Author = {Arizmendi, C and Wang, S and Kaplan, S and Weinfurt,
K},
Title = {Evaluating Recall Periods for Patient-Reported Outcome
Measures: A Systematic Review of Quantitative
Methods.},
Journal = {Value Health},
Volume = {27},
Number = {4},
Pages = {518-526},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1016/j.jval.2024.01.016},
Abstract = {OBJECTIVES: The current guidance for selection of recall
periods recommends considering the design of the study,
nature of the condition, patient's burden and ability to
recall, and intent of the outcome measure. Empirical study
of the accuracy of recall periods is recommended; however,
there is not consensus on how to quantitatively evaluate the
consistency of results from patient-reported outcome
measures (PROMs) with different recall periods. We conducted
a systematic review to describe quantitative methods for
evaluating results obtained from PROMs with differing recall
periods to lay the groundwork for establishing consensus.
METHODS: We searched MEDLINE, Embase, Scopus, and American
Psychological Association PsycINFO for studies where
participants are given the same health-related measure (eg,
quality of life, well-being, functioning, and pain) with
differing recall periods. RESULTS: A total of 7174 abstracts
were screened. The 30 included studies reflected a wide
range of domains, including pain, fatigue, and sexual
behavior and function. The recall periods ranged from
momentary to 6 months. The analytic approaches varied,
including different methods for assessing relative
agreement, absolute agreement, and for assessing combined
relative and absolute agreement. CONCLUSIONS: We found
variability in how PROM recall periods were evaluated,
suggesting an opportunity for greater consensus on
methodological approach. As a starting point, we provide
recommendations for which methods are preferred for which
contexts.},
Doi = {10.1016/j.jval.2024.01.016},
Key = {fds376698}
}
@article{fds375248,
Author = {Weinfurt, KP and Flynn, K},
Title = {Some Clarifications Regarding the PROMIS© SexFS: Commentary
on Clements et al. (2023).},
Journal = {Arch Sex Behav},
Volume = {53},
Number = {3},
Pages = {869-870},
Year = {2024},
Month = {March},
url = {http://dx.doi.org/10.1007/s10508-023-02789-y},
Doi = {10.1007/s10508-023-02789-y},
Key = {fds375248}
}
@article{fds375347,
Author = {Green, T and Bosworth, HB and Coronado, GD and DeBar, L and Green, BB and Huang, SS and Jarvik, JG and Mor, V and Zatzick, D and Weinfurt, KP and Check, DK},
Title = {Factors Affecting Post-trial Sustainment or
De-implementation of Study Interventions: A Narrative
Review.},
Journal = {J Gen Intern Med},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1007/s11606-023-08593-7},
Abstract = {In contrast to traditional randomized controlled trials,
embedded pragmatic clinical trials (ePCTs) are conducted
within healthcare settings with real-world patient
populations. ePCTs are intentionally designed to align with
health system priorities leveraging existing healthcare
system infrastructure and resources to ease intervention
implementation and increase the likelihood that effective
interventions translate into routine practice following the
trial. The NIH Pragmatic Trials Collaboratory, funded by the
National Institutes of Health (NIH), supports the conduct of
large-scale ePCT Demonstration Projects that address major
public health issues within healthcare systems. The
Collaboratory has a unique opportunity to draw on the
Demonstration Project experiences to generate lessons
learned related to ePCTs and the dissemination and
implementation of interventions tested in ePCTs. In this
article, we use case studies from six completed
Demonstration Projects to summarize the Collaboratory's
experience with post-trial interpretation of results, and
implications for sustainment (or de-implementation) of
tested interventions. We highlight three key lessons
learned. First, ineffective interventions (i.e., ePCT is
null for the primary outcome) may be sustained if they have
other measured benefits (e.g., secondary outcome or
subgroup) or even perceived benefits (e.g., staff like the
intervention). Second, effective interventions-even those
solicited by the health system and/or designed with
significant health system partner buy-in-may not be
sustained if they require significant resources. Third,
alignment with policy incentives is essential for achieving
sustainment and scale-up of effective interventions. Our
experiences point to several recommendations to aid in
considering post-trial sustainment or de-implementation of
interventions tested in ePCTs: (1) include secondary outcome
measures that are salient to health system partners; (2)
collect all appropriate data to allow for post hoc analysis
of subgroups; (3) collect experience data from clinicians
and staff; (4) engage policy-makers before starting the
trial.},
Doi = {10.1007/s11606-023-08593-7},
Key = {fds375347}
}
@article{fds370913,
Author = {Morain, SR and Bollinger, J and Weinfurt, K and Sugarman,
J},
Title = {Stakeholder perspectives on data sharing from pragmatic
clinical trials: Unanticipated challenges for meeting
emerging requirements},
Journal = {Learning Health Systems},
Volume = {8},
Number = {1},
Year = {2024},
Month = {January},
url = {http://dx.doi.org/10.1002/lrh2.10366},
Abstract = {Introduction: Numerous arguments have been advanced for
broadly sharing de-identified, participant-level clinical
trial data. However, data sharing in pragmatic clinical
trials (PCTs) presents ethical challenges. While prior
scholarship has described aspects of PCTs that raise
distinct considerations for data sharing, there have been no
reports of the experiences of those at the leading edge of
data-sharing efforts for PCTs, including how these
particular challenges have been navigated. To address this
gap, we conducted interviews with key stakeholders, with a
focus on the ethical issues presented by sharing data from
PCTs. Methods: We recruited respondents using purposive
sampling to reflect the range of stakeholder groups affected
by efforts to expand PCT data sharing. Through
semi-structured interviews, we explored respondents'
experiences and perceptions about sharing de-identified,
individual-level data from PCTs. An integrated approach was
used to identify and describe key themes. Results: We
conducted 40 interviews between April and September 2022.
Five overarching themes emerged through analysis: (1)
challenges in sharing data collected under a waiver or
alteration of consent; (2) conflicting views regarding PCT
patient-subject preferences for data sharing; (3)
identification of respect-promoting practices beyond
consent; (4) concerns about elevated risks or burdens from
sharing PCT data; and (5) diverse views about the likely
benefits resulting from sharing PCT data. Conclusion: Our
data indicate unresolved tensions in how to fulfill the
expectation to broadly share de-identified, individual-level
data from PCTs, and suggest that those promulgating and
implementing data-sharing policies must be sensitive to
PCT-specific considerations. Future work could inform
efforts to tailor data-sharing policy and practice to
reflect the challenges presented by PCTs, including sharing
experiences from trials that have successfully navigated
these tensions.},
Doi = {10.1002/lrh2.10366},
Key = {fds370913}
}
@article{fds372842,
Author = {Bernstein, SM and Barks, MC and Ubel, PA and Weinfurt, K and Barlet, MH and Farley, S and Jiao, MG and Bansal, S and Fisher, K and Lemmon,
ME},
Title = {Prognostic Discordance Among Parents and Physicians Caring
for Infants with Neurologic Conditions.},
Journal = {J Pediatr},
Volume = {263},
Pages = {113677},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1016/j.jpeds.2023.113677},
Abstract = {OBJECTIVE: To determine the frequency, degree, and nature of
prognostic discordance between parents and physicians caring
for infants with neurologic conditions. STUDY DESIGN: In
this observational cohort study, we enrolled parents and
physicians caring for infants with neurologic conditions in
advance of a family conference. Parent-physician dyads
completed a postconference survey targeting expected
neurologic outcomes across 3 domains (motor, speech, and
cognition) using a 6-point scale. Prognostic discordance was
defined as a difference of ≥2 response options and was
considered moderate (difference of 2-3 response options) or
high (difference of 4-5 response options). Responses were
categorized as differences in belief and/or differences in
understanding using an existing paradigm. RESULTS: Forty
parent-physician dyads of 28 infants completed surveys.
Parent-physician discordance about prognosis occurred in
≥1 domain in the majority of dyads (n = 28/40, 70%).
Discordance was generally moderate in degree (n = 23/28,
82%) and occurred with similar frequency across all domains.
Of parent-physician dyads with discordance, the majority
contained a difference in understanding in at least 1 domain
(n = 25/28, 89%), while a minority contained a difference
of belief (n = 6/28, 21%). When discordance was present,
parents were typically more optimistic in their predictions
compared with physicians (n = 25/28, 89%). CONCLUSIONS:
Differing perceptions about the prognosis of critically ill
infants are common and due to differences in both
understanding and belief. These findings can be used to
develop targeted interventions to improve prognostic
communication.},
Doi = {10.1016/j.jpeds.2023.113677},
Key = {fds372842}
}
@article{fds374241,
Author = {Nash, AL and Bloom, DL and Chapman, BM and Wheeler, SB and McGuire, KP and Lee, CN and Weinfurt, K and Rosenstein, DL and Plichta, JK and Vann,
JCJ and Hwang, ES},
Title = {ASO Visual Abstract: Contralateral Prophylactic Mastectomy
Decision Making-The Partners' Perspective.},
Journal = {Ann Surg Oncol},
Volume = {30},
Number = {13},
Pages = {8481-8482},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1245/s10434-023-14184-x},
Doi = {10.1245/s10434-023-14184-x},
Key = {fds374241}
}
@article{fds372425,
Author = {Nash, AL and Bloom, DL and Chapman, BM and Wheeler, SB and McGuire, KP and Lee, CN and Weinfurt, K and Rosenstein, DL and Plichta, JK and Vann,
JCJ and Hwang, ES},
Title = {Contralateral Prophylactic Mastectomy Decision-Making: The
Partners' Perspective.},
Journal = {Ann Surg Oncol},
Volume = {30},
Number = {10},
Pages = {6268-6274},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1245/s10434-023-14022-0},
Abstract = {BACKGROUND: The rate of contralateral prophylactic
mastectomy (CPM) continues to rise despite no improvement in
survival, an increased risk of surgical complications, and
negative effects on quality of life. This study explored the
experiences of the partners of women who undergo CPM.
METHODS: This study was part of an investigation into the
factors motivating women with early-stage unilateral breast
cancer and low genetic risk to opt for contralateral
prophylactic mastectomy (CPM). Participating women were
asked for permission to invite their partners to take part
in interviews. In-depth interviews with partners were
conducted using a semi-structured topic guide. A thematic
analysis of the data was performed RESULTS: Of 35 partners,
all men, 15 agreed to be interviewed. Most perceived their
role to be strong and logical. Some hoped their wives would
choose a bilateral mastectomy. All felt strongly that the
final decision was up to their partners. The partners often
framed the decision for CPM as one of life or death. Thus,
any aesthetic effects were unimportant by comparison. The
male partners had difficulty grasping the physical and
emotional changes inherent in mastectomy, which made
communicating about sexuality and intimacy very challenging
for the couples. In the early recovery period, some noted
the stress of managing home life. CONCLUSIONS: The
experiences of the male partners provide insight into how
couples navigate complex treatment decision-making, both
together and separately. There may be a benefit to including
partners in pre- and post-surgical counseling to mitigate
miscommunication regarding the expected oncologic and
emotional outcomes related to CPM.},
Doi = {10.1245/s10434-023-14022-0},
Key = {fds372425}
}
@article{fds372841,
Author = {Nayak, A and Alkaitis, MS and Nayak, K and Nikolov, M and Weinfurt, KP and Schulman, K},
Title = {Comparison of History of Present Illness Summaries Generated
by a Chatbot and Senior Internal Medicine
Residents.},
Journal = {JAMA Intern Med},
Volume = {183},
Number = {9},
Pages = {1026-1027},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1001/jamainternmed.2023.2561},
Doi = {10.1001/jamainternmed.2023.2561},
Key = {fds372841}
}
@article{fds370293,
Author = {Coles, TM and Lin, L and Weinfurt, K and Reeve, BB and Spertus, JA and Mentz, RJ and Piña, IL and Bocell, FD and Tarver, ME and Saha, A and Caldwell, B},
Title = {Investigating Potential Gender-Based Differential Item
Functioning for Items in the Kansas City Cardiomyopathy
Questionnaire (KCCQ) Physical Limitations
Domain},
Journal = {Applied Research in Quality of Life},
Volume = {18},
Number = {4},
Pages = {1785-1798},
Year = {2023},
Month = {August},
url = {http://dx.doi.org/10.1007/s11482-023-10162-3},
Abstract = {Women with heart failure report worse health-related quality
of life on average, than men. This may result from actual
differences in care or differing interpretations of and
responses to survey questions. We investigated potential
gender-based differential item functioning on the Kansas
City Cardiomyopathy Questionnaire (KCCQ) Physical
Limitations domain. Using data from the HF-ACTION trial, a
multicenter, randomized controlled trial of exercise
training in patients with chronic heart failure with reduced
ejection fraction (661 women, 1670 men), we assessed
gender-based differential item functioning using a Wald test
based on item response theory and ordinal logistic
regression. Both methods evaluated how men and women
responded to each KCCQ item after adjusting for physical
limitation status. No item exhibited statistically
significant differential item functioning using the Wald
method. Two items exhibited differential item functioning
using the ordinal logistic regression method (KCCQ1e:
Climbing a flight of stairs without stopping; KCCQ1f:
Hurrying or jogging) (P < 0.01), but the magnitude of
differential item functioning was negligible. To accurately
measure patient-reported outcomes, it is important to
evaluate potential biases that may influence the ability to
compare patient subgroups. The magnitude of differential
item functioning on a 5-item KCCQ Physical Limitation domain
was negligible.},
Doi = {10.1007/s11482-023-10162-3},
Key = {fds370293}
}
@article{fds370912,
Author = {Weinfurt, KP},
Title = {Developing, Selecting, and Modifying Performance Outcome
Assessments.},
Journal = {Value Health},
Volume = {26},
Number = {7},
Pages = {957-958},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1016/j.jval.2023.04.011},
Doi = {10.1016/j.jval.2023.04.011},
Key = {fds370912}
}
@article{fds371137,
Author = {Oehrlein, EM and US Food and Drug Administration
Interviewees},
Title = {An Interview With the Food and Drug Administration About
Draft Patient-Focused Drug Development Guidance 3:
Selecting, Developing, or Modifying Fit-for-Purpose Clinical
Outcome Assessments.},
Journal = {Value Health},
Volume = {26},
Number = {6},
Pages = {791-795},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1016/j.jval.2023.04.006},
Doi = {10.1016/j.jval.2023.04.006},
Key = {fds371137}
}
@article{fds370390,
Author = {Harper, JD and Desai, AC and Maalouf, NM and Yang, H and Antonelli, JA and Tasian, GE and Lai, HH and Reese, PP and Curatolo, M and Kirkali, Z and Al-Khalidi, HR and Wessells, H and Scales, CD},
Title = {Risk Factors for Increased Stent-associated Symptoms
Following Ureteroscopy for Urinary Stones: Results From
STENTS.},
Journal = {J Urol},
Volume = {209},
Number = {5},
Pages = {971-980},
Year = {2023},
Month = {May},
url = {http://dx.doi.org/10.1097/JU.0000000000003183},
Abstract = {PURPOSE: The STudy to Enhance uNderstanding of
sTent-associated Symptoms sought to identify risk factors
for pain and urinary symptoms, as well as how these symptoms
interfere with daily activities after ureteroscopy for stone
treatment. MATERIALS AND METHODS: This prospective
observational cohort study enrolled patients aged ≥12
years undergoing ureteroscopy with ureteral stent for stone
treatment at 4 clinical centers. Participants reported
symptoms at baseline; on postoperative days 1, 3, 5; at
stent removal; and day 30 post-stent removal. Outcomes of
pain intensity, pain interference, urinary symptoms, and
bother were captured with multiple instruments.
Multivariable analyses using mixed-effects linear regression
models were identified characteristics associated with
increased stent-associated symptoms. RESULTS: A total of 424
participants were enrolled. Mean age was 49 years (SD 17);
47% were female. Participants experienced a marked increase
in stent-associated symptoms on postoperative day 1. While
pain intensity decreased ∼50% from postoperative day 1 to
postoperative day 5, interference due to pain remained
persistently elevated. In multivariable analysis, older age
was associated with lower pain intensity (P = .004). Having
chronic pain conditions (P < .001), prior severe stent pain
(P = .021), and depressive symptoms at baseline (P < .001)
were each associated with higher pain intensity. Neither
sex, stone location, ureteral access sheath use, nor stent
characteristics were drivers of stent-associated symptoms.
CONCLUSIONS: In this multicenter cohort, interference
persisted even as pain intensity decreased. Patient factors
(eg, age, depression) rather than surgical factors were
associated with symptom intensity. These findings provide a
foundation for patient-centered care and highlight potential
targets for efforts to mitigate the burden of
stent-associated symptoms.},
Doi = {10.1097/JU.0000000000003183},
Key = {fds370390}
}
@article{fds367788,
Author = {Coles, TM and Lucas, N and McFatrich, M and Henke, D and Ridgeway, JL and Behnken, EM and Weinfurt, K and Reeve, BB and Corneli, A and Dunlay, SM and Spertus, JA and Lin, L and Piña, IL and Bocell, FD and Tarver, ME and Dohse, H and Saha, A and Caldwell, B},
Title = {Investigating gender-based differential item functioning on
the Kansas City Cardiomyopathy Questionnaire (KCCQ) using
qualitative content analysis.},
Journal = {Qual Life Res},
Volume = {32},
Number = {3},
Pages = {841-852},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1007/s11136-022-03276-y},
Abstract = {PURPOSE: The purpose of this study is to evaluate potential
gender-based differences in interpreting the Kansas City
Cardiomyopathy Questionnaire (KCCQ-23) and to explore if
there are aspects of health-related quality of life (HRQOL)
not captured by the KCCQ-23 that are important to assess in
men and/or women with heart failure (HF). METHODS:
Patients ≥ 22 years of age with clinician-diagnosed
HF and left ventricular ejection fraction ≤ 40% were
recruited from two academic medical centers to participate
in semi-structured concept elicitation and cognitive
debriefing interviews. Enrollment was stratified by
patient-identified gender (half women/half men). All
interviews were conducted over the phone/web and audio
recorded. Interviews were transcribed and descriptive
qualitative content analysis was used to summarize findings
overall and by gender. RESULTS: Twenty-five adults (56%
women) diagnosed with HF participated. The average age was
67 years (range: 25-88). Women attributed a wider variety
of symptoms to HF than men. Some participants had difficulty
differentiating whether their experiences were due to HF,
side effects of their medications, or age. We found very
little evidence that participants interpreted KCCQ-23 items
differently based on gender. CONCLUSIONS: Overall, our
findings indicate that interpretation of the KCCQ-23 items
were similar in men and women. However, some modifications
to items may improve clarity of interpretation for a wide
range of patients.},
Doi = {10.1007/s11136-022-03276-y},
Key = {fds367788}
}
@article{fds369096,
Author = {Marsolo, KA and Weinfurt, KP and Staman, KL and Hammill,
BG},
Title = {Moving From Idealism to Realism With Data
Sharing.},
Journal = {Ann Intern Med},
Volume = {176},
Number = {3},
Pages = {402-403},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.7326/M22-2973},
Doi = {10.7326/M22-2973},
Key = {fds369096}
}
@article{fds369236,
Author = {Staman, KL and Check, DK and Zatzick, D and Mor, V and Fritz, JM and Sluka,
K and DeBar, LL and Jarvik, JG and Volandes, A and Coronado, GD and Chambers, DA and Weinfurt, KP and George, SZ},
Title = {Intervention delivery for embedded pragmatic clinical
trials: Development of a tool to measure
complexity.},
Journal = {Contemp Clin Trials},
Volume = {126},
Pages = {107105},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1016/j.cct.2023.107105},
Abstract = {BACKGROUND: Conducting an embedded pragmatic clinical trial
in the workflow of a healthcare system is a complex
endeavor. The complexity of the intervention delivery can
have implications for study planning, ability to maintain
fidelity to the intervention during the trial, and/or
ability to detect meaningful differences in outcomes.
METHODS: We conducted a literature review, developed a tool,
and conducted two rounds of phone calls with NIH Pragmatic
Trials Collaboratory Demonstration Project principal
investigators to develop the Intervention Delivery
Complexity Tool. After refining the tool, we piloted it with
Collaboratory demonstration projects and developed an online
version of the tool using the R Shiny application
(https://duke-som.shinyapps.io/ICT-ePCT/). RESULTS: The
6-item tool consists of internal and external factors.
Internal factors pertain to the intervention itself and
include workflow, training, and the number of intervention
components. External factors are related to intervention
delivery at the system level including differences in
healthcare systems, the dependency on setting for
implementation, and the number of steps between the
intervention and the outcome. CONCLUSION: The Intervention
Delivery Complexity Tool was developed as a standard way to
overcome communication challenges of intervention delivery
within an embedded pragmatic trial. This version of the tool
is most likely to be useful to the trial team and its health
system partners during trial planning and conduct. We expect
further evolution of the tool as more pragmatic trials are
conducted and feedback is received on its performance
outside of the NIH Pragmatic Trials Collaboratory.},
Doi = {10.1016/j.cct.2023.107105},
Key = {fds369236}
}
@article{fds363744,
Author = {Coles, TM and Lin, L and Weinfurt, K and Reeve, BB and Spertus, JA and Mentz, RJ and Piña, IL and Bocell, FD and Tarver, ME and Henke, DM and Saha, A and Caldwell, B and Spring, S},
Title = {Do PRO Measures Function the Same Way for all Individuals
With Heart Failure?},
Journal = {J Card Fail},
Volume = {29},
Number = {2},
Pages = {210-216},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1016/j.cardfail.2022.05.017},
Abstract = {Women diagnosed with heart failure report worse quality of
life than men on patient-reported outcome (PRO) measures. An
inherent assumption of PRO measures in heart failure is that
women and men interpret questions about quality of life the
same way. If this is not the case, the risk then becomes
that the PRO scores cannot be used for valid comparison or
to combine outcomes by subgroups of the population.
Inability to compare subgroups validly is a broad issue and
has implications for clinical trials, and it also has
specific and important implications for identifying and
beginning to address health inequities. We describe this
threat to validity (the psychometric term is differential
item functioning), why it is so important in heart-failure
outcomes, the research that has been conducted thus far in
this area, the gaps that remain, and what we can do to avoid
this threat to validity. PROs bring unique information to
clinical decision making, and the validity of PRO measures
is key to interpreting differences in heart failure
outcomes.},
Doi = {10.1016/j.cardfail.2022.05.017},
Key = {fds363744}
}
@article{fds370546,
Author = {Hovén, E and Flynn, KE and Weinfurt, KP and Eriksson, LE and Wettergren, L},
Title = {Psychometric evaluation of the Swedish version of the PROMIS
Sexual Function and Satisfaction Measures in clinical and
nonclinical young adult populations.},
Journal = {Sexual medicine},
Volume = {11},
Number = {1},
Pages = {qfac006},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1093/sexmed/qfac006},
Abstract = {<h4>Background</h4>The Patient-Reported Outcomes Measurement
Information System (PROMIS®) Sexual Function and
Satisfaction (SexFS) version 2.0 measurement tool was
developed to assess sexual functioning and satisfaction in
the general population regardless of health condition and
sexual orientation.<h4>Aim</h4>The study aimed to evaluate
the psychometric properties of the Swedish version of the
PROMIS SexFS measure in clinical and nonclinical populations
of young adults (aged <40 years).<h4>Methods</h4>The SexFS
was answered by a clinical population of young adult women
(<i>n</i> = 180) and men (<i>n</i> = 110) with
breast cancer and testicular cancer, respectively, and a
nonclinical population of young adult women
(<i>n</i> = 511) and men (<i>n</i> = 324) from the
general population. Psychometric properties were evaluated
by examining data quality (score distribution, floor and
ceiling effects, proportion of missing data), construct
validity (corrected item, total correlation, scaling
success), and reliability (Cronbach α).<h4>Outcomes</h4>The
following domains of the SexFS 2.0 were investigated:
Vaginal Lubrication, Vaginal Discomfort, Vulvar Discomfort-
Clitoral, Vulvar Discomfort- Labial, Erectile Function,
Interest in Sexual Activity, Satisfaction With Sex Life,
Orgasm- Ability, and Orgasm- Pleasure.<h4>Results</h4>The
Swedish version of the SexFS 2.0 generated data of
acceptable quality. Some noteworthy floor or ceiling effects
were identified across domains and respondent groups.
Corrected item totals were used to express the coherence
between an item and the other items in the domain. The
correlation coefficients were above 0.40 for all items,
except for 1 of the items within the Vaginal Discomfort
domain and for the items in the Erectile Function domain in
the nonclinical group of men. High proportions of scaling
success were noted across domains (96%-100%). Reliability
was satisfactory (α = 0.74-0.92) for all domains, expect
for Erectile Function of the nonclinical group (α = 0.53),
due to low variability in item responses, which was improved
somewhat (α = 0.65) when combined with the clinical
group.<h4>Clinical implications</h4>A flexible tool to
measure self-reported sexual function and satisfaction in
young men and women is available for researchers and
clinicians in Sweden.<h4>Strengths and limitations</h4>The
nationwide population-based sample of patients with cancer,
identified from national quality registers, minimized
selection bias. However, men in the general population had a
lower response rate (34%) compared to the other groups,
which introduced a risk of bias in estimates. The
psychometric evaluation was limited to young adults (aged
19-40 years).<h4>Conclusion</h4>The results provide
evidence for the validity and reliability of the Swedish
version of the SexFS measure for the assessment of sexual
functioning and satisfaction in young adults from both
clinical and nonclinical populations.},
Doi = {10.1093/sexmed/qfac006},
Key = {fds370546}
}
@article{fds367787,
Author = {Locklear, T and Lewis, R and Calhoun, F and Li, A and Dickerson, KC and McMillan, A and Davis, L and Dzirasa, K and Weinfurt, KP and Grambow,
SC},
Title = {Advancing workforce diversity by leveraging the Clinical and
Translational Science Awards (CTSA) program.},
Journal = {J Clin Transl Sci},
Volume = {7},
Number = {1},
Pages = {e30},
Publisher = {Cambridge University Press (CUP)},
Year = {2023},
url = {http://dx.doi.org/10.1017/cts.2022.489},
Abstract = {Clinical trials continue to disproportionately
underrepresent people of color. Increasing representation of
diverse backgrounds among clinical research personnel has
the potential to yield greater representation in clinical
trials and more efficacious medical interventions by
addressing medical mistrust. In 2019, North Carolina Central
University (NCCU), a Historically Black College and
University with a more than 80% underrepresented student
population, established the Clinical Research Sciences
Program with support from the Clinical and Translational
Science Awards (CTSA) program at neighboring Duke
University. This program was designed to increase exposure
of students from diverse educational, racial, and ethnic
backgrounds to the field of clinical research, with a
special focus on health equity education. In the first year,
the program graduated 11 students from the two-semester
certificate program, eight of whom now hold positions as
clinical research professionals. This article describes how
leveraging the CTSA program helped NCCU build a framework
for producing a highly trained, competent, and diverse
workforce in clinical research responsive to the call for
increased diversity in clinical trial participation.},
Doi = {10.1017/cts.2022.489},
Key = {fds367787}
}
%% Welsh-Bohmer, Kathleen A.
@article{fds374980,
Author = {Farrer, TJ and Bigler, ED and Tsui-Caldwell, YHW and Abildskov, TJ and Tschanz, JT and Welsh-Bohmer, KA},
Title = {Scheltens ratings, clinical white matter hyperintensities
and executive functioning in the Cache County Memory
Study.},
Journal = {Appl Neuropsychol Adult},
Pages = {1-7},
Year = {2023},
Month = {December},
url = {http://dx.doi.org/10.1080/23279095.2023.2287140},
Abstract = {OBJECTIVE: Examine the association between
neuropsychologically assessed executive function and
clinically identifiable white matter burden from magnetic
resonance imaging, using a visual rating system (Scheltens
Rating System) applied to the Cache County Memory Study
(CCMS) archival database. METHOD: We used the Scheltens
Ratings Scale to quantify white matter lesion burden in the
CCMS sample and used this metric as a predictor of executive
function. The sample included 60 individuals with dementia
and 13 healthy controls. RESULTS: Higher Scheltens ratings
were associated with poorer task performance on an Executive
Function composite score of common neuropsychological tests.
This association held true for both controls and dementing
cases. CONCLUSIONS: The current findings support extensive
prior literature demonstrating the association between brain
vascular health determined by white matter burden and
clinical outcomes based on neuropsychological assessment of
cognitive performance.},
Doi = {10.1080/23279095.2023.2287140},
Key = {fds374980}
}
@article{fds370292,
Author = {Blair, EM and Reale, BK and Zahuranec, DB and Forman, J and Langa, KM and Giordani, BJ and Plassman, BL and Welsh-Bohmer, KA and Wang, J and Kollman, CD and Levine, DA},
Title = {Influence of mild cognitive impairment on patient and care
partner decision-making for acute ischemic
stroke.},
Journal = {J Stroke Cerebrovasc Dis},
Volume = {32},
Number = {6},
Pages = {107068},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2023.107068},
Abstract = {GOALS: Evidence suggests that patients with mild cognitive
impairment (MCI) receive fewer treatments for acute ischemic
stroke and other cardiovascular diseases than patients with
normal cognition. Little is known about how patient and care
partner preferences for ischemic stroke treatment differ
between the patient population with MCI and the population
with normal cognition. This study aimed to understand how
patient MCI diagnosis influences patient and care partner
decision-making for acute ischemic stroke treatments.
METHODS: Multi-center qualitative study using in-person
semi-structured interviews with 20 MCI and normal cognition
patient-care partner dyads using a standard guide. The
present study reports results on patient and care partner
preferences for a clinical vignette patient to receive three
non-invasive treatments (intravenous tissue plasminogen
activator, inpatient rehabilitation, and secondary
preventive medications) and two invasive treatments (feeding
tube and carotid endarterectomy) after acute ischemic
stroke. We used qualitative content analysis to identify
themes. FINDINGS: We identified three major themes: (1)
Patients with MCI desired non-invasive treatments after
stroke, similar to patients with normal cognition and for
similar reasons; (2) Patients with MCI expressed different
preferences than patients with normal cognition for two
invasive treatments after stroke: carotid endarterectomy and
feeding tube placement; and (3) Patients with MCI expressed
more skepticism of the stroke treatment options and less
decisiveness in decision-making than patients with normal
cognition. CONCLUSIONS: These results suggest that patient
MCI diagnosis may contribute to differences in patient and
care partner preferences for invasive treatments after
stroke, but not for non-invasive treatments.},
Doi = {10.1016/j.jstrokecerebrovasdis.2023.107068},
Key = {fds370292}
}
@article{fds371156,
Author = {Grazia, A and Altomare, D and Preis, L and Monsch, AU and Cappa, SF and Gauthier, S and Frölich, L and Winblad, B and Welsh-Bohmer, KA and Teipel, SJ and Boccardi, M and Consortium for the Harmonization of
Neuropsychological Assessment},
Title = {Feasibility of a standard cognitive assessment in European
academic memory clinics.},
Journal = {Alzheimers Dement},
Volume = {19},
Number = {6},
Pages = {2276-2286},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1002/alz.12830},
Abstract = {INTRODUCTION: Standardized cognitive assessment would
enhance diagnostic reliability across memory clinics. An
expert consensus adapted the Uniform Dataset (UDS)-3 for
European centers, the clinician's UDS (cUDS). This study
assessed its implementation acceptability and feasibility.
METHODS: We developed a survey investigating barriers,
facilitators, and willingness to implement the cUDS. With a
mixed-methods design, we analyzed data from academic memory
clinics. RESULTS: Seventy-eight percent of responding
clinicians were experienced neuropsychologists/psychologists
and 22% were medical specialists coming from 18 European
countries. Sixty-five percent clinicians were willing to
implement cUDS. General barriers related to implementation
(43%) and clinical-methodological domains (21%). Favorable
clinicians reported finances (15%) and digitalization (9%)
as facilitating, but unavailability of local norms (23%) as
hindering. Unfavorable clinicians reported logistical (23%)
and time issues (18%). DISCUSSION: Despite challenges, data
showed moderate clinicians' acceptability and requirements
to improve feasibility. Nonetheless, these results come from
academic clinicians. The next steps will require feasibility
evaluation in non-academic contexts.},
Doi = {10.1002/alz.12830},
Key = {fds371156}
}
@article{fds371673,
Author = {Huggins, LKL and Min, SH and Kaplan, S and Wei, J and Welsh-Bohmer, K and Xu, H},
Title = {Meta-Analysis of Variations in Association between APOE ɛ4
and Alzheimer's Disease and Related Dementias Across
Hispanic Regions of Origin.},
Journal = {J Alzheimers Dis},
Volume = {93},
Number = {3},
Pages = {1095-1109},
Year = {2023},
url = {http://dx.doi.org/10.3233/JAD-221167},
Abstract = {BACKGROUND: Emerging research has shown racial and ethnic
variations in the magnitude of association between the
apolipoprotein ɛ4 (APOE ɛ4) allele and the risk of
developing Alzheimer's disease and related dementias (ADRD).
Studies researching this association among Hispanic groups
within and outside of the United States have produced
inconsistent results. OBJECTIVE: To examine the association
between the APOE ɛ4 allele and the risk of developing ADRD
in global Hispanic populations from different ethnic regions
of origin. METHODS: PubMed, Embase, Scopus, and PsycInfo
were searched for studies relating to Hispanic/Latin
American origin, APOE ɛ4, and ADRD. Odds ratios (OR) of
ADRD risk for individuals with APOE ɛ4 versus those without
APOE ɛ4 were extracted and calculated using random effects
analysis. RESULTS: 20 eligible studies represented Caribbean
Hispanic, Mexican, South American, Spanish, and Cuban
groups. Overall, APOE ɛ4 was significantly associated with
increased risk of ADRD (Odds Ratio [OR] 3.80, 95% CI:
2.38-6.07). The association was only significant in the
South American (OR: 4.61, 95% CI: 2.74-7.75) subgroup.
CONCLUSION: There was an association between APOE ɛ4 and
increased ADRD risk for the South American subgroup. The
strength of this association varied across Hispanic
subgroups. Data is limited with more studies especially
needed for adjusted analysis on Spanish, Central American,
Cuban Hispanic, and Caribbean Hispanic groups. Results
suggest additional environmental or genetic risk factors are
associated with ethnic variations.},
Doi = {10.3233/JAD-221167},
Key = {fds371673}
}
@article{fds372749,
Author = {Zou, H and Luo, S and Liu, H and Lutz, MW and Bennett, DA and Plassman, BL and Welsh-Bohmer, KA},
Title = {Genotypic Effects of the TOMM40'523 Variant and APOE on
Longitudinal Cognitive Change over 4 Years: The TOMMORROW
Study.},
Journal = {J Prev Alzheimers Dis},
Volume = {10},
Number = {4},
Pages = {886-894},
Year = {2023},
url = {http://dx.doi.org/10.14283/jpad.2023.115},
Abstract = {BACKGROUND: The 523 poly-T length polymorphism (rs10524523)
in TOMM40 has been reported to influence longitudinal
cognitive test performance within APOE ε3/3 carriers. The
results from prior studies are inconsistent. It is also
unclear whether specific APOE and TOMM40 genotypes
contribute to heterogeneity in longitudinal cognitive
performance during the preclinical stages of AD. OBJECTIVES:
To determine the effects of these genes on longitudinal
cognitive change in early preclinical stages of AD, we used
the clinical trial data from the recently concluded
TOMMORROW study to examine the effects of APOE and TOMM40
genotypes on neuropsychological test performance. DESIGN: A
phase 3, double-blind, placebo-controlled, randomized
clinical trial. SETTING: Academic affiliated and private
research clinics in Australia, Germany, Switzerland, the UK,
and the USA. PARTICIPANTS: Cognitively normal older adults
aged 65 to 83. INTERVENTION: Pioglitazone tablet.
MEASUREMENTS: Participants from the TOMMORROW trial were
stratified based on APOE genotype (APOE ε3/3, APOE ε3/4,
APOE ε4/4). APOE ε3/3 carriers were further stratified by
TOMM40'523 genotype. The final analysis dataset consists of
1,330 APOE ε3/3 carriers and 7,001 visits. Linear mixed
models were used to compare the rates of decline in
cognition across APOE groups and the APOE ε3/3 carriers
with different TOMM40'523 genotypes. RESULTS: APOE ε3/4 and
APOE ε4/4 genotypes compared with the APOE ε3/3 genotype
were associated with worse performance on measures of global
cognition, episodic memory, and expressive language.
Further, over the four years of observation, the APOE ε3/3
carriers with the TOMM40'523-S/S genotype showed better
global cognition and accelerated rates of cognitive decline
on tests of global cognition, executive function, and
attentional processing compared to APOE ε3/3 carriers with
TOMM40'523-S/VL and VL/VL genotypes and compared to the APOE
ε3/4 and APOE ε4/4 carriers. CONCLUSIONS: We suggest that
both APOE and TOMM40 genotypes may independently contribute
to cognitive heterogeneity in the pre-MCI stages of AD.
Controlling for this genetic variability will be important
in clinical trials designed to slow the rate of cognitive
decline and/or prevent symptom onset in preclinical
AD.},
Doi = {10.14283/jpad.2023.115},
Key = {fds372749}
}
@article{fds373574,
Author = {Watts, A and Haneline, S and Welsh-Bohmer, KA and Wu, J and Alexander,
R and Swerdlow, RH and Burns, DK and Saunders, AM},
Title = {TOMM40 '523 Genotype Distinguishes Patterns of Cognitive
Improvement for Executive Function in APOEɛ3
Homozygotes.},
Journal = {J Alzheimers Dis},
Volume = {95},
Number = {4},
Pages = {1697-1707},
Year = {2023},
url = {http://dx.doi.org/10.3233/JAD-230066},
Abstract = {BACKGROUND: TOMM40 '523 has been associated with cognitive
performance and risk for developing Alzheimer's disease
independent of the effect of APOE genotype. Few studies have
considered the longitudinal effect of this genotype on
change in cognition over time. OBJECTIVE: Our objective was
to evaluate the relationship between TOMM40 genotype status
and change in cognitive performance in the TOMMORROW study,
which was designed to prospectively evaluate an algorithm
that includes TOMM40 '523 for genetic risk for conversion to
mild cognitive impairment. METHODS: We used latent growth
curve models to estimate the effect of TOMM40 allele carrier
(short, very long) status on the intercept and slope of
change in cognitive performance in four broad cognitive
domains (attention, memory, executive function, and
language) and a combined overall cognitive score over 30
months. RESULTS: TOMM40 very long allele carriers had
significantly lower baseline performance for the combined
overall cognitive function score (B = -0.088,
p = 0.034) and for the executive function domain score
(B = -0.143, p = 0.013). Slopes for TOMM40 very long
carriers had significantly greater increases over time for
the executive function domain score only. In sensitivity
analyses, the results for executive function were observed
in participants who remained clinically stable, but not in
those who progressed clinically over the study duration.
CONCLUSIONS: Our results add to the growing body of evidence
that TOMM40, in the absence of APOEɛ4, may contribute to
cognitive changes with aging and dementia and support the
view that mitochondrial function is an important contributor
to Alzheimer's disease risk.},
Doi = {10.3233/JAD-230066},
Key = {fds373574}
}
@article{fds373575,
Author = {Welsh-Bohmer, KA and Kerchner, GA and Dhadda, S and Garcia, M and Miller, DS and Natanegara, F and Raket, LL and Robieson, W and Siemers,
ER and Carrillo, MC and Weber, CJ},
Title = {Decision making in clinical trials: Interim analyses,
innovative design, and biomarkers.},
Journal = {Alzheimers Dement (N Y)},
Volume = {9},
Number = {4},
Pages = {e12421},
Year = {2023},
url = {http://dx.doi.org/10.1002/trc2.12421},
Abstract = {The efficient and accurate execution of clinical trials
testing novel treatments for Alzheimer's disease (AD) is a
critical component of the field's collective efforts to
develop effective disease-modifying treatments for AD. The
lengthy and heterogeneous nature of clinical progression in
AD contributes to the challenges inherent in demonstrating a
clinically meaningful benefit of any potential new AD
therapy. The failure of many large and expensive clinical
trials to date has prompted a focus on optimizing all
aspects of decision making, to not only expedite the
development of new treatments, but also maximize the value
of the information that each clinical trial yields, so that
all future clinical trials (including those that are
negative) will contribute toward advancing the field. To
address this important topic the Alzheimer's Association
Research Roundtable convened December 1-2, 2020. The goals
focused around identifying new directions and actionable
steps to enhance clinical trial decision making in planned
future studies.},
Doi = {10.1002/trc2.12421},
Key = {fds373575}
}
@article{fds135097,
Title = {Hulette, C.M., Welsh-Bohmer, K.A., Murray, M.G., Mash, D.&
McIntyre, L.M. Neuropathological and neuropsychological
changes in "normal" aging: Evidence for preclinical
Alzheimer's disease. Journal of Neuropathology and
Experimental Neurology, 57, 1168-1174.},
Key = {fds135097}
}
%% White, Leonard E.
@article{fds372236,
Title = {Correction for Johnson et al., Merged magnetic resonance and
light sheet microscopy of the whole mouse
brain.},
Journal = {Proc Natl Acad Sci U S A},
Volume = {120},
Number = {25},
Pages = {e2308718120},
Year = {2023},
Month = {June},
url = {http://dx.doi.org/10.1073/pnas.2308718120},
Doi = {10.1073/pnas.2308718120},
Key = {fds372236}
}
@article{fds371023,
Author = {Johnson, GA and Tian, Y and Ashbrook, DG and Cofer, GP and Cook, JJ and Gee, JC and Hall, A and Hornburg, K and Kaczorowski, CC and Qi, Y and Yeh,
F-C and Wang, N and White, LE and Williams, RW},
Title = {Merged magnetic resonance and light sheet microscopy of the
whole mouse brain.},
Journal = {Proc Natl Acad Sci U S A},
Volume = {120},
Number = {17},
Pages = {e2218617120},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1073/pnas.2218617120},
Abstract = {We have developed workflows to align 3D magnetic resonance
histology (MRH) of the mouse brain with light sheet
microscopy (LSM) and 3D delineations of the same specimen.
We start with MRH of the brain in the skull with gradient
echo and diffusion tensor imaging (DTI) at 15 μm isotropic
resolution which is ~ 1,000 times higher than that of most
preclinical MRI. Connectomes are generated with
superresolution tract density images of ~5 μm. Brains are
cleared, stained for selected proteins, and imaged by LSM at
1.8 μm/pixel. LSM data are registered into the reference
MRH space with labels derived from the ABA common coordinate
framework. The result is a high-dimensional integrated volume with registration
(HiDiver) with alignment precision better than 50 µm.
Throughput is sufficiently high that HiDiver is being used
in quantitative studies of the impact of gene variants and
aging on mouse brain cytoarchitecture and
connectomics.},
Doi = {10.1073/pnas.2218617120},
Key = {fds371023}
}
@article{fds371024,
Author = {Hornburg, KJ and Slosky, LM and Cofer, G and Cook, J and Qi, Y and Porkka,
F and Clark, NB and Pires, A and Petrella, JR and White, LE and Wetsel, WC and Barak, L and Caron, MG and Johnson, GA},
Title = {Prenatal heroin exposure alters brain morphology and
connectivity in adolescent mice.},
Journal = {NMR Biomed},
Volume = {36},
Number = {2},
Pages = {e4842},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1002/nbm.4842},
Abstract = {The United States is experiencing a dramatic increase in
maternal opioid misuse and, consequently, the number of
individuals exposed to opioids in utero. Prenatal opioid
exposure has both acute and long-lasting effects on health
and wellbeing. Effects on the brain, often identified at
school age, manifest as cognitive impairment, attention
deficit, and reduced scholastic achievement. The
neurobiological basis for these effects is poorly
understood. Here, we examine how in utero exposure to heroin
affects brain development into early adolescence in a mouse
model. Pregnant C57BL/6J mice received escalating doses of
heroin twice daily on gestational days 4-18. The brains of
offspring were assessed on postnatal day 28 using 9.4 T
diffusion MRI of postmortem specimens at 36 μm
resolution. Whole-brain volumes and the volumes of 166
bilateral regions were compared between heroin-exposed and
control offspring. We identified a reduction in whole-brain
volume in heroin-exposed offspring and heroin-associated
volume changes in 29 regions after standardizing for
whole-brain volume. Regions with bilaterally reduced
standardized volumes in heroin-exposed offspring relative to
controls include the ectorhinal and insular cortices.
Regions with bilaterally increased standardized volumes in
heroin-exposed offspring relative to controls include the
periaqueductal gray, septal region, striatum, and
hypothalamus. Leveraging microscopic resolution diffusion
tensor imaging and precise regional parcellation, we
generated whole-brain structural MRI diffusion connectomes.
Using a dimension reduction approach with multivariate
analysis of variance to assess group differences in the
connectome, we found that in utero heroin exposure altered
structure-based connectivity of the left septal region and
the region that acts as a hub for limbic regulatory actions.
Consistent with clinical evidence, our findings suggest that
prenatal opioid exposure may have effects on brain
morphology, connectivity, and, consequently, function that
persist into adolescence. This work expands our
understanding of the risks associated with opioid misuse
during pregnancy and identifies biomarkers that may
facilitate diagnosis and treatment.},
Doi = {10.1002/nbm.4842},
Key = {fds371024}
}
@article{fds373579,
Author = {Tian, Y and Johnson, GA and Williams, RW and White,
LE},
Title = {A rapid workflow for neuron counting in combined light sheet
microscopy and magnetic resonance histology.},
Journal = {Front Neurosci},
Volume = {17},
Pages = {1223226},
Year = {2023},
url = {http://dx.doi.org/10.3389/fnins.2023.1223226},
Abstract = {Information on regional variation in cell numbers and
densities in the CNS provides critical insight into
structure, function, and the progression of CNS diseases.
However, variability can be real or a consequence of methods
that do not account for technical biases, including
morphologic deformations, errors in the application of cell
type labels and boundaries of regions, errors of counting
rules and sampling sites. We address these issues in a mouse
model by introducing a workflow that consists of the
following steps: 1. Magnetic resonance histology (MRH) to
establish the size, shape, and regional morphology of the
mouse brain in situ. 2. Light-sheet microscopy (LSM) to
selectively label neurons or other cells in the entire brain
without sectioning artifacts. 3. Register LSM volumes to MRH
volumes to correct for dissection errors and both global and
regional deformations. 4. Implement stereological protocols
for automated sampling and counting of cells in 3D LSM
volumes. This workflow can analyze the cell densities of one
brain region in less than 1 min and is highly replicable in
cortical and subcortical gray matter regions and structures
throughout the brain. This method demonstrates the advantage
of not requiring an extensive amount of training data,
achieving a F1 score of approximately 0.9 with just 20
training nuclei. We report deformation-corrected neuron
(NeuN) counts and neuronal density in 13 representative
regions in 5 C57BL/6J cases and 2 BXD strains. The data
represent the variability among specimens for the same brain
region and across regions within the specimen. Neuronal
densities estimated with our workflow are within the range
of values in previous classical stereological studies. We
demonstrate the application of our workflow to a mouse model
of aging. This workflow improves the accuracy of neuron
counting and the assessment of neuronal density on a
region-by-region basis, with broad applications for studies
of how genetics, environment, and development across the
lifespan impact cell numbers in the CNS.},
Doi = {10.3389/fnins.2023.1223226},
Key = {fds373579}
}
%% Whitman, Ethan
@article{fds375964,
Author = {Whitman, ET and Ryan, CP and Abraham, WC and Addae, A and Corcoran, DL and Elliott, ML and Hogan, S and Ireland, D and Keenan, R and Knodt, AR and Melzer, TR and Poulton, R and Ramrakha, S and Sugden, K and Williams,
BS and Zhou, J and Hariri, AR and Belsky, DW and Moffitt, TE and Caspi, A and Alzheimer’s Disease Neuroimaging Initiative},
Title = {A blood biomarker of the pace of aging is associated with
brain structure: replication across three
cohorts.},
Journal = {Neurobiology of aging},
Volume = {136},
Pages = {23-33},
Year = {2024},
Month = {April},
url = {http://dx.doi.org/10.1016/j.neurobiolaging.2024.01.008},
Abstract = {Biological aging is the correlated decline of multi-organ
system integrity central to the etiology of many age-related
diseases. A novel epigenetic measure of biological aging,
DunedinPACE, is associated with cognitive dysfunction,
incident dementia, and mortality. Here, we tested for
associations between DunedinPACE and structural MRI
phenotypes in three datasets spanning midlife to advanced
age: the Dunedin Study (age=45 years), the Framingham Heart
Study Offspring Cohort (mean age=63 years), and the
Alzheimer's Disease Neuroimaging Initiative (mean age=75
years). We also tested four additional epigenetic measures
of aging: the Horvath clock, the Hannum clock, PhenoAge, and
GrimAge. Across all datasets (total N observations=3380;
total N individuals=2322), faster DunedinPACE was associated
with lower total brain volume, lower hippocampal volume,
greater burden of white matter microlesions, and thinner
cortex. Across all measures, DunedinPACE and GrimAge had the
strongest and most consistent associations with brain
phenotypes. Our findings suggest that single timepoint
measures of multi-organ decline such as DunedinPACE could be
useful for gauging nervous system health.},
Doi = {10.1016/j.neurobiolaging.2024.01.008},
Key = {fds375964}
}
%% Woldorff, Marty G.
@article{fds365726,
Author = {Gjorgieva, E and Geib, BR and Cabeza, R and Woldorff,
MG},
Title = {The influence of imagery vividness and internally-directed
attention on the neural mechanisms underlying the encoding
of visual mental images into episodic memory.},
Journal = {Cerebral Cortex},
Volume = {33},
Number = {6},
Pages = {3207-3220},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1093/cercor/bhac270},
Abstract = {Attention can be directed externally toward sensory
information or internally toward self-generated information.
Using electroencephalography (EEG), we investigated the
attentional processes underlying the formation and encoding
of self-generated mental images into episodic memory.
Participants viewed flickering words referring to common
objects and were tasked with forming visual mental images of
the objects and rating their vividness. Subsequent memory
for the presented object words was assessed using an old-new
recognition task. Internally-directed attention during image
generation was indexed as a reduction in steady-state visual
evoked potentials (SSVEPs), oscillatory EEG responses at the
frequency of a flickering stimulus. The results yielded 3
main findings. First, SSVEP power driven by the flickering
word stimuli decreased as subjects directed attention
internally to form the corresponding mental image. Second,
SSVEP power returned to pre-imagery baseline more slowly for
low- than high-vividness later remembered items, suggesting
that longer internally-directed attention is required to
generate subsequently remembered low-vividness images.
Finally, the event-related-potential difference due to
memory was more sustained for subsequently remembered low-
versus high-vividness items, suggesting that additional
conceptual processing may have been needed to remember the
low-vividness visual images. Taken together, the results
clarify the neural mechanisms supporting the encoding of
self-generated information.},
Doi = {10.1093/cercor/bhac270},
Key = {fds365726}
}
@article{fds368085,
Author = {Pinhas, M and Paulsen, DJ and Woldorff, MG and Brannon,
EM},
Title = {Neurophysiological signatures of approximate number system
acuity in preschoolers.},
Journal = {Trends in Neuroscience and Education},
Volume = {30},
Pages = {100197},
Year = {2023},
Month = {March},
url = {http://dx.doi.org/10.1016/j.tine.2022.100197},
Abstract = {BACKGROUND: A hallmark of the approximate number system
(ANS) is ratio dependence. Previous work identified specific
event-related potentials (ERPs) that are modulated by
numerical ratio throughout the lifespan. In adults, ERP
ratio dependence was correlated with the precision of the
numerical judgments with individuals who make more precise
judgments showing larger ratio-dependent ERP effects. The
current study evaluated if this relationship generalizes to
preschoolers. METHOD: ERPs were recorded from 56 4.5 to
5.5-year-olds while they compared the numerosity of two
sequentially presented dot arrays. Nonverbal numerical
precision, often called ANS acuity, was assessed using a
similar behavioral task. RESULTS: Only children with high
ANS acuity exhibited a P2p ratio-dependent effect onsetting
∼250 ms after the presentation of the comparison dot
array. Furthermore, P2p amplitude positively correlated with
ANS acuity across tasks. CONCLUSION: Results demonstrate
developmental continuity between preschool years and
adulthood in the neural basis of the ANS.},
Doi = {10.1016/j.tine.2022.100197},
Key = {fds368085}
}
%% Wyly, Skyler
@article{fds374237,
Author = {Wyly, S and Jinon, N and Francis, T and Evans, H and Kao, TL and Lambert,
S and Montgomery, S and Newlove, M and Mariscal, H and Nguyen, H and Cole,
H and Aispuro, I and Robledo, D and Tenaglia, O and Weinberger, N and Nguyen, B and Waits, H and Jorian, D and Koch-Kreher, L and Myrdal, H and Antoniou, V and Warrier, M and Wunsch, L and Arce, I and Kirchner, K and Campos, E and Nguyen, A and Rodriguez, K and Cao, L and Halmekangas, A and Wilson, RC},
Title = {The psychophysiology of Mastermind: Characterizing response
times and blinking in a high-stakes television game
show.},
Journal = {Psychophysiology},
Pages = {e14485},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1111/psyp.14485},
Abstract = {Television game shows have proven to be a valuable resource
for studying human behavior under conditions of high stress
and high stakes. However, previous work has focused mostly
on choices-ignoring much of the rich visual information that
is available on screen. Here, we take a first step to
extracting more of this information by investigating the
response times and blinking of contestants in the BBC show
Mastermind. In Mastermind, contestants answer rapid-fire
quiz questions while a camera slowly zooms in on their
faces. By labeling contestants' behavior and blinks from 25
episodes, we asked how accuracy, response times, and
blinking varied over the course of the game. For accuracy
and response times, we tested whether contestants responded
more accurately and more slowly after an error-exhibiting
the "post-error increase in accuracy" and "post-error
slowing" which has been repeatedly observed in the lab. For
blinking, we tested whether blink rates varied according to
the cognitive demands of the game-decreasing during periods
of cognitive load, such as when pondering a response, and
increasing at event boundaries in the task, such as the
start of a question. In contrast to the lab, evidence for
post-error changes in accuracy and response time was weak,
with only marginal effects observed. In line with the lab,
blinking varied over the course of the game much as we
predicted. Overall, our findings demonstrate the potential
of extracting dynamic signals from game shows to study the
psychophysiology of behavior in the real
world.},
Doi = {10.1111/psyp.14485},
Key = {fds374237}
}
%% Yin, Henry
@book{fds373559,
Author = {Yin, HH},
Title = {The integrative functions of the basal ganglia},
Pages = {1-319},
Year = {2023},
Month = {November},
ISBN = {9781498768696},
url = {http://dx.doi.org/10.1201/9780429154461},
Abstract = {This volume is the first comprehensive and single-authored
book on the functions of the basal ganglia. The goal is to
provide a new synthesis of diverse areas of research on the
basal ganglia, from cellular mechanisms of synaptic
transmission and plasticity to neural circuit mechanisms
underlying behavior. A global theory of basal ganglia
function incorporating research from the last 40 years is
presented. I hope to explain for the first time how the
basal ganglia generate behavior, how they contribute to
learning and memory, and how impairments in basal ganglia
function can lead to neurological and psychiatric disorders.
Features: • The only single-authored book on the basal
ganglia with coverage of the latest literature • Spans
multiple levels of analysis, from cellular physiology to
behavior • Includes coverage of clinical symptoms,
encompassing neuropsychology, movement disorders, and
psychiatric disorders • Discusses the role of the basal
ganglia in learning and memory.},
Doi = {10.1201/9780429154461},
Key = {fds373559}
}
@article{fds374571,
Author = {Friedman, AD and Yin, HH},
Title = {Selective Activation of Subthalamic Nucleus Output
Quantitatively Scales Movements.},
Journal = {The Journal of neuroscience : the official journal of the
Society for Neuroscience},
Volume = {43},
Number = {47},
Pages = {7967-7981},
Year = {2023},
Month = {November},
url = {http://dx.doi.org/10.1523/jneurosci.0734-23.2023},
Abstract = {The subthalamic nucleus (STN) is a common target for deep
brain stimulation (DBS) treatments of Parkinsonian motor
symptoms. According to the dominant model, the STN output
can suppress movement by enhancing inhibitory basal ganglia
(BG) output via the indirect pathway, and disrupting STN
output using DBS can restore movement in Parkinson's
patients. But the mechanisms underlying STN DBS remain
poorly understood, as previous studies usually relied on
electrical stimulation, which cannot selectively target STN
output neurons. Here, we selectively stimulated STN
projection neurons using optogenetics and quantified
behavior in male and female mice using 3D motion capture.
STN stimulation resulted in movements with short latencies
(10-15 ms). A single pulse of light was sufficient to
generate movement, and there was a highly linear
relationship between stimulation frequency and kinematic
measures. Unilateral stimulation caused movement in the
ipsiversive direction (toward the side of stimulation) and
quantitatively determined head yaw and head roll, while
stimulation of either STN raises the head (pitch). Bilateral
stimulation does not cause turning but raised the head twice
as high as unilateral stimulation of either STN. Optogenetic
stimulation increased the firing rate of STN neurons in a
frequency-dependent manner, and the increased firing is
responsible for stimulation-induced movements. Finally,
stimulation of the STN's projection to the brainstem
mesencephalic locomotor region was sufficient to reproduce
the behavioral effects of STN stimulation. These results
question the common assumption that the STN suppresses
movement, and instead suggest that STN output can precisely
specify action parameters via direct projections to the
brainstem.<b>SIGNIFICANCE STATEMENT</b> Our results question
the common assumption that the subthalamic nucleus (STN)
suppresses movement, and instead suggest that STN output can
precisely specify action parameters via direct projections
to the brainstem.},
Doi = {10.1523/jneurosci.0734-23.2023},
Key = {fds374571}
}
@article{fds372780,
Author = {Ulloa Severino and FP and Lawal, OO and Sakers, K and Wang, S and Kim, N and Friedman, AD and Johnson, SA and Sriworarat, C and Hughes, RH and Soderling, SH and Kim, IH and Yin, HH and Eroglu,
C},
Title = {Training-induced circuit-specific excitatory synaptogenesis
in mice is required for effort control.},
Journal = {Nat Commun},
Volume = {14},
Number = {1},
Pages = {5522},
Year = {2023},
Month = {September},
url = {http://dx.doi.org/10.1038/s41467-023-41078-z},
Abstract = {Synaptogenesis is essential for circuit development;
however, it is unknown whether it is critical for the
establishment and performance of goal-directed voluntary
behaviors. Here, we show that operant conditioning via
lever-press for food reward training in mice induces
excitatory synapse formation onto a subset of anterior
cingulate cortex neurons projecting to the dorsomedial
striatum (ACC→DMS). Training-induced synaptogenesis is
controlled by the Gabapentin/Thrombospondin receptor
α2δ-1, which is an essential neuronal protein for proper
intracortical excitatory synaptogenesis. Using germline and
conditional knockout mice, we found that deletion of α2δ-1
in the adult ACC→DMS circuit diminishes training-induced
excitatory synaptogenesis. Surprisingly, this manipulation
does not impact learning but results in a significant
increase in effort exertion without affecting sensitivity to
reward value or changing contingencies. Bidirectional
optogenetic manipulation of ACC→DMS neurons rescues or
phenocopies the behaviors of the α2δ-1 cKO mice,
highlighting the importance of synaptogenesis within this
cortico-striatal circuit in regulating effort
exertion.},
Doi = {10.1038/s41467-023-41078-z},
Key = {fds372780}
}
@article{fds371505,
Author = {Fallon, IP and Hughes, RN and Severino, FPU and Kim, N and Lawry, CM and Watson, GDR and Roshchina, M and Yin, HH},
Title = {The role of the parafascicular thalamic nucleus in action
initiation and steering.},
Journal = {Current biology : CB},
Volume = {33},
Number = {14},
Pages = {2941-2951.e4},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1016/j.cub.2023.06.025},
Abstract = {The parafascicular (Pf) nucleus of the thalamus has been
implicated in arousal and attention, but its contributions
to behavior remain poorly characterized. Here, using
in vivo and in vitro electrophysiology, optogenetics, and
3D motion capture, we studied the role of the Pf nucleus in
behavior using a continuous reward-tracking task in freely
moving mice. We found that many Pf neurons precisely
represent vector components of velocity, with a strong
preference for ipsiversive movements. Their activity usually
leads velocity, suggesting that Pf output is critical for
self-initiated orienting behavior. To test this hypothesis,
we expressed excitatory or inhibitory opsins in VGlut2+ Pf
neurons to manipulate neural activity bidirectionally. We
found that selective optogenetic stimulation of these
neurons consistently produced ipsiversive head turning,
whereas inhibition stopped turning and produced downward
movements. Taken together, our results suggest that the Pf
nucleus can send continuous top-down commands that specify
detailed action parameters (e.g., direction and speed of the
head), thus providing guidance for orienting and steering
during behavior.},
Doi = {10.1016/j.cub.2023.06.025},
Key = {fds371505}
}
@article{fds371654,
Author = {Naffaa, MM and Khan, RR and Kuo, CT and Yin, HH},
Title = {Cortical regulation of neurogenesis and cell proliferation
in the ventral subventricular zone.},
Journal = {Cell reports},
Volume = {42},
Number = {7},
Pages = {112783},
Year = {2023},
Month = {July},
url = {http://dx.doi.org/10.1016/j.celrep.2023.112783},
Abstract = {Neurogenesis and differentiation of neural stem cells (NSCs)
are controlled by cell-intrinsic molecular pathways that
interact with extrinsic signaling cues. In this study, we
identify a circuit that regulates neurogenesis and cell
proliferation in the lateral ventricle-subventricular zone
(LV-SVZ). Our results demonstrate that direct glutamatergic
projections from the anterior cingulate cortex (ACC), as
well as inhibitory projections from calretinin<sup>+</sup>
local interneurons, modulate the activity of cholinergic
neurons in the subependymal zone (subep-ChAT<sup>+</sup>).
Furthermore, in vivo optogenetic stimulation and inhibition
of the ACC-subep-ChAT<sup>+</sup> circuit are sufficient to
control neurogenesis in the ventral SVZ. Both
subep-ChAT<sup>+</sup> and local calretinin<sup>+</sup>
neurons play critical roles in regulating ventral SVZ
neurogenesis and LV-SVZ cell proliferation.},
Doi = {10.1016/j.celrep.2023.112783},
Key = {fds371654}
}
@article{fds365542,
Author = {Zhang, J and Hughes, RN and Kim, N and Fallon, IP and Bakhurin, K and Kim,
J and Severino, FPU and Yin, HH},
Title = {A one-photon endoscope for simultaneous patterned
optogenetic stimulation and calcium imaging in freely
behaving mice.},
Journal = {Nature biomedical engineering},
Volume = {7},
Number = {4},
Pages = {499-510},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.1038/s41551-022-00920-3},
Abstract = {Optogenetics and calcium imaging can be combined to
simultaneously stimulate and record neural activity in vivo.
However, this usually requires two-photon microscopes, which
are not portable nor affordable. Here we report the design
and implementation of a miniaturized one-photon endoscope
for performing simultaneous optogenetic stimulation and
calcium imaging. By integrating digital micromirrors, the
endoscope makes it possible to activate any neuron of choice
within the field of view, and to apply arbitrary
spatiotemporal patterns of photostimulation while imaging
calcium activity. We used the endoscope to image striatal
neurons from either the direct pathway or the indirect
pathway in freely moving mice while activating any chosen
neuron in the field of view. The endoscope also allows for
the selection of neurons based on their relationship with
specific animal behaviour, and to recreate the behaviour by
mimicking the natural neural activity with photostimulation.
The miniaturized endoscope may facilitate the study of how
neural activity gives rise to behaviour in freely moving
animals.},
Doi = {10.1038/s41551-022-00920-3},
Key = {fds365542}
}
@article{fds370886,
Author = {Petter, EA and Fallon, IP and Hughes, RN and Watson, GDR and Meck, WH and Ulloa Severino and FP and Yin, HH},
Title = {Elucidating a locus coeruleus-dentate gyrus dopamine pathway
for operant reinforcement.},
Journal = {eLife},
Volume = {12},
Pages = {e83600},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.7554/elife.83600},
Abstract = {Animals can learn to repeat behaviors to earn desired
rewards, a process commonly known as reinforcement learning.
While previous work has implicated the ascending
dopaminergic projections to the basal ganglia in
reinforcement learning, little is known about the role of
the hippocampus. Here, we report that a specific population
of hippocampal neurons and their dopaminergic innervation
contribute to operant self-stimulation. These neurons are
located in the dentate gyrus, receive dopaminergic
projections from the locus coeruleus, and express D1
dopamine receptors. Activation of D1 + dentate neurons is
sufficient for self-stimulation: mice will press a lever to
earn optogenetic activation of these neurons. A similar
effect is also observed with selective activation of the
locus coeruleus projections to the dentate gyrus, and
blocked by D1 receptor antagonism. Calcium imaging of D1 +
dentate neurons revealed significant activity at the time of
action selection, but not during passive reward delivery.
These results reveal the role of dopaminergic innervation of
the dentate gyrus in supporting operant reinforcement.},
Doi = {10.7554/elife.83600},
Key = {fds370886}
}
%% Zucker, Nancy L.
@article{fds373560,
Author = {Zucker, NL and Strauss, GP and Smyth, JM and Scherf, KS and Brotman, MA and Boyd, RC and Choi, J and Davila, M and Ajilore, OA and Gunning, F and Schweitzer, JB},
Title = {Experimental Therapeutics: Opportunities and Challenges
Stemming From the National Institute of Mental Health
Workshop on Novel Target Discovery and Psychosocial
Intervention Development.},
Journal = {Perspect Psychol Sci},
Pages = {17456916231197980},
Year = {2023},
Month = {October},
url = {http://dx.doi.org/10.1177/17456916231197980},
Abstract = {There has been slow progress in the development of
interventions that prevent and/or reduce mental-health
morbidity and mortality. The National Institute of Mental
Health (NIMH) launched an experimental-therapeutics
initiative with the goal of accelerating the development of
effective interventions. The emphasis is on interventions
designed to engage a target mechanism. A target mechanism is
a process (e.g., behavioral, neurobiological) proposed to
underlie change in a defined clinical endpoint and through
change in which an intervention exerts its effect. This
article is based on discussions from an NIMH workshop
conducted in February 2020 and subsequent conversations
among researchers using this approach. We discuss the
components of an experimental-therapeutics approach such as
clinical-outcome selection, target definition and
measurement, intervention design and selection, and
implementation of a team-science strategy. We emphasize the
important contributions of different constituencies (e.g.,
patients, caregivers, providers) in deriving hypotheses
about novel target mechanisms. We highlight strategies for
target-mechanism identification using published and
hypothetical examples. We consider the decision-making
dilemmas that arise with different patterns of results in
purported mechanisms and clinical outcomes. We end with
considerations of the practical challenges of this approach
and the implications for future directions of this
initiative.},
Doi = {10.1177/17456916231197980},
Key = {fds373560}
}
@article{fds370370,
Author = {Andrade, FC and Erwin, S and Burnell, K and Jackson, J and Storch, M and Nicholas, J and Zucker, N},
Title = {Intervening on Social Comparisons on Social Media:
Electronic Daily Diary Pilot Study.},
Journal = {JMIR Ment Health},
Volume = {10},
Pages = {e42024},
Year = {2023},
Month = {April},
url = {http://dx.doi.org/10.2196/42024},
Abstract = {BACKGROUND: Literature has underscored the dark aspects of
social media use, including associations with depressive
symptoms, feelings of social isolation, and diminished
self-esteem. Social comparison, the process of evaluating
oneself relative to another person, is thought to contribute
to these negative experiences such that people with a
stronger tendency to compare themselves with others are
particularly susceptible to the detrimental effects of
social media. Social media as a form of social connection
and communication is nevertheless an inevitable-and arguably
integral-part of life, particularly for young adults.
Therefore, there is a need to investigate strategies that
could alter the manner in which people interact with social
media to minimize its detrimental effects and maximize the
feelings of affiliation and connection. OBJECTIVE: This
pilot study examined the feasibility, acceptability, and
effectiveness of a brief web-based intervention designed to
alter engagement with social media and promote psychological
well-being by encouraging social savoring as an alternative
to social comparison. Social savoring was operationalized as
experiencing joyful emotions related to the happiness of
someone else's experiences (ie, feeling happy for someone
else). METHODS: Following an intensive longitudinal design,
55 college students (mean age 19.29, SD 0.93 years; n=43,
78% women and n=23, 42% White) completed baseline measures
(individual differences, psychological well-being,
connectedness, and social media use) and then 14 days of
daily surveys on their social media activity and well-being.
On day 8, the group that was randomized to receive the
intervention watched a video instructing them on the skill
of social savoring and was asked to practice this skill
during days 8 to 14. RESULTS: Overall, participants reported
positive perceptions of the intervention. Participants who
watched the intervention video reported significantly higher
performance self-esteem (P=.02) at posttest than those in
the control condition, after controlling for baseline
levels. Participants also reported significantly higher
state self-esteem (P=.01) on days in which they engaged in
more social savoring while using social media, and the use
of social savoring increased significantly (P=.01) over
time, suggesting that participants found it helpful.
Participants in both conditions reported significantly lower
levels of social comparison (control: P=.01; intervention:
P=.002) and higher levels of connectedness (control: P<.001;
intervention: P=.001) at posttest than at baseline.
CONCLUSIONS: Initial evidence from this pilot study suggests
that a web-based social savoring intervention may help
minimize the potentially harmful consequences of social
media use, at least in some domains. Future work is needed
to examine the effectiveness and acceptance of this
intervention in different age groups and in clinical samples
that are in part characterized by higher levels of
comparison with others (eg, people with eating
disorders).},
Doi = {10.2196/42024},
Key = {fds370370}
}
@article{fds369354,
Author = {Crone, C and Fochtmann, LJ and Attia, E and Boland, R and Escobar, J and Fornari, V and Golden, N and Guarda, A and Jackson-Triche, M and Manzo,
L and Mascolo, M and Pierce, K and Riddle, M and Seritan, A and Uniacke, B and Zucker, N and Yager, J and Craig, TJ and Hong, S-H and Medicus,
J},
Title = {The American Psychiatric Association Practice Guideline for
the Treatment of Patients With Eating Disorders.},
Journal = {Am J Psychiatry},
Volume = {180},
Number = {2},
Pages = {167-171},
Year = {2023},
Month = {February},
url = {http://dx.doi.org/10.1176/appi.ajp.23180001},
Doi = {10.1176/appi.ajp.23180001},
Key = {fds369354}
}
@misc{fds373959,
Author = {Zucker, NL and Pilato, IB and Lemay-Russell, S},
Title = {Feeding difficulties: Difficulty swallowing and the fear of
aversive consequences},
Pages = {164-176},
Booktitle = {Pediatric Psychogastroenterology: A Handbook for Mental
Health Professionals},
Year = {2023},
Month = {January},
ISBN = {9781032312347},
url = {http://dx.doi.org/10.4324/9781003308683-15},
Abstract = {This chapter provides a detailed understanding of the
emergence of fears of aversive consequences broadly and more
specifically in youth with avoidant/restrictive food intake
disorder (ARFID), practice guidance on differentially
assessing ARFID from other related psychiatric disorders,
and guidance on tools to address these fears in youth. ARFID
is characterized by a pattern of restrictive or avoidant
eating resulting in malnourishment, a low body weight,
dependence on enteral feeding or supplements, and/or a
significant impact on their psychosocial functioning. The
chapter explores the role of maladaptive fear-learning in
the context of eating challenges in pediatric
gastrointestinal disorders. Assessment of fears in children
ideally should integrate data from multiple reporters
including youth and parents. Treatment of somatic fears
typically aims to create new learning experiences that
demonstrate the safety of a previously feared stimulus. For
some youth, food restriction is so severe that they must be
placed on supplemental or replacement tube
feeding.},
Doi = {10.4324/9781003308683-15},
Key = {fds373959}
}
@article{fds136119,
Title = {Zucker, N.L., Losh, M., Bulik, C.M., Labar, K.S., Piven, J.,
& Pelphrey, K.A. (in press). Anorexia Nervosa and Autism
Spectrum Disorders: Guided Investigation of Social Cognitive
Endophenotypes, Psychological Bulletin.},
Key = {fds136119}
}