Publications of John M. Mercer :chronological by type listing:
%%
@article{fds229102,
Author = {De la Mora and JF and Mercer, JM},
Title = {A modified Fokker-Planck equation for the motion of Brownian
particles in a non-uniform gas},
Journal = {Physical Review A},
Volume = {26},
Pages = {2178-2185},
Year = {1982},
Key = {fds229102}
}
@article{fds229110,
Author = {Kronauer, DJC and Bergmann, PJ and Mercer, JM and Russell,
AP},
Title = {A phylogeographically distinct and deep divergence in the
widespread Neotropical turnip-tailed gecko, Thecadactylus
rapicauda.},
Journal = {Molecular phylogenetics and evolution},
Volume = {34},
Number = {2},
Pages = {431-437},
Year = {2005},
Month = {February},
ISSN = {1055-7903},
url = {http://www.ncbi.nlm.nih.gov/pubmed/15619453},
Doi = {10.1016/j.ympev.2004.10.009},
Key = {fds229110}
}
@article{fds229107,
Author = {Laurie, CC and True, JR and Liu, J and Mercer, JM},
Title = {An introgression analysis of quantitative trait loci that
contribute to a morphological difference between Drosophila
simulans and D. mauritiana.},
Journal = {Genetics},
Volume = {145},
Number = {2},
Pages = {339-348},
Year = {1997},
Month = {February},
ISSN = {0016-6731},
url = {http://www.ncbi.nlm.nih.gov/pubmed/9071588},
Abstract = {Drosophila simulans and D. mauritiana differ markedly in
morphology of the posterior lobe, a male-specific genitalic
structure. Both size and shape of the lobe can be quantified
by a morphometric variable, PCl, derived from principal
components and Fourier analyses. The genetic architecture of
the species difference in PCl was investigated previously by
composite interval mapping, which revealed largely additive
inheritance, with a minimum of eight quantitative trait loci
(QTL) affecting the trait. This analysis was extended by
introgression of marked segments of the mauritiana third
chromosome into a simulans background by repeated
backcrossing. The two types of experiment are consistent in
suggesting that several QTL on the third chromosome may have
effects in the range of 10-15% of the parental difference
and that all or nearly all QTL have effects in the same
direction. Since the parental difference is large (30.4
environmental standard deviations), effects of this
magnitude can produce alternative homozygotes with little
overlap in phenotype. However, these estimates may not
reflect the effects of individual loci, since each interval
or introgressed segment may contain multiple QTL. The
consistent direction of allelic effects suggests a history
of directional selection on the posterior
lobe.},
Doi = {10.1093/genetics/145.2.339},
Key = {fds229107}
}
@misc{fds300296,
Author = {Mercer, JM},
Title = {Cooperativity},
Series = {2nd},
Pages = {183-187},
Booktitle = {Sydney Brenner's Encyclopedia of Genetics},
Publisher = {Elsevier},
Editor = {Maloy, S and Hughes, K},
Year = {2013},
ISBN = {9780123749840},
url = {http://dx.doi.org/10.1016/B978-0-12-374984-0.00339-9},
Abstract = {Cooperativity subsumes a diverse set of phenomena, including
ligand-protein, protein-protein, and protein-DNA
interactions, covalent modification of proteins, membrane
assembly, and protein folding. In its usual sense the
allosteric interaction promotes (positive cooperativity) or
reduces (negative cooperativity) the expected function of a
macromolecular complex. The principal manifestation of
cooperativity is a sigmoidal (S-shaped) binding or reaction
rate (response) curve that facilitates a nearly bimodal
change of state over a narrow range of a control variable
upon which a response depends. Sigmoid curves are typically
modeled by the Hill equation. Curves with Hill coefficients
greater than (positive cooperativity) or less than (negative
cooperativity) 1 are usually considered diagnostic of
cooperativity, and, with their principal response in a
narrow range, are reminiscent of switch-like behavior,
although they transition continuously and in a state of
equilibrium between their unactivated and activated form
without bistability. Cooperativity is in widespread use in
the economy of cells including metabolic control, cell cycle
control, ligand binding and transport, genetic switches
(bistability), signaling, threshold phenomena, development,
protein folding, and membrane assembly. Mathematical
expressions incorporating cooperativity are frequent
components of mathematical models of cellular processes, and
may also be translated into design elements of switches and
oscillators in synthetic biology.},
Doi = {10.1016/B978-0-12-374984-0.00339-9},
Key = {fds300296}
}
@article{fds229105,
Author = {True, JR and Mercer, JM and Laurie, CC},
Title = {Differences in crossover frequency and distribution among
three sibling species of Drosophila.},
Journal = {Genetics},
Volume = {142},
Number = {2},
Pages = {507-523},
Year = {1996},
Month = {February},
ISSN = {0016-6731},
url = {http://www.ncbi.nlm.nih.gov/pubmed/8852849},
Abstract = {Comparisons of the genetic and cytogenetic maps of three
sibling species of Drosophila reveal marked differences in
the frequency and cumulative distribution of crossovers
during meiosis. The maps for two of these species,
Drosophila melanogaster and D. simulans, have previously
been described, while this report presents new map data for
D. mauritiana, obtained using a set of P element markers. A
genetic map covering nearly the entire genome was
constructed by estimating the recombination fraction for
each pair of adjacent inserts. The P-based genetic map of
mauritiana is approximately 1.8 times longer than the
standard melanogaster map. It appears that mauritiana has
higher recombination along the entire length of each
chromosome, but the difference is greates in
centromere-proximal regions of the autosomes. The mauritiana
autosomes show little or no centromeric recombinational
suppression, a characteristic that is prominent in
melanogaster. D. simulans appears to be intermediate both in
terms of total map length and intensity of the autosomal
centromeric effect. These interspecific differences in
recombination have important evolutionary implications for
DNA sequence organization and variability. In particular,
mauritiana is expected to differ from melanogaster in
patterns and amounts of sequence variation and transposon
insertions.},
Doi = {10.1093/genetics/142.2.507},
Key = {fds229105}
}
@article{fds229097,
Author = {Louise Roth and V and Mercer, JM},
Title = {Differing rates of macroevolutionary diversification in
arboreal squirrels},
Journal = {Current Science},
Volume = {95},
Number = {7},
Pages = {857-861},
Year = {2008},
Month = {October},
ISSN = {0011-3891},
Abstract = {Current diversity is the result of macroevolutionary
processes of origination and extinction of lineages through
time. Here we make use of a fossil-calibrated
molecular-clock phylogeny of modern squirrel genera to
estimate both rates of 'birth' and 'death', and the net rate
of accumulation of lineages since the origin of the squirrel
family (Sciuridae) 36 Ma. As a family, the Sciuridae have
exhibited modest rates of diversification in comparison with
other mammalian clades. Within the Sciuridae, lineages of
squirrels have accumulated at higher rates in geographically
localized subclades in the tropics of different continents.
The rate is strikingly high in the Sciurini of South
America, which first entered and radiated within that
continent comparatively recently (less than 3 Ma). It is
noteworthy that the most rapidly diversifying groups are
also relatively young. Because extinctions lag behind
originations, the effects of extinction are not yet
detectable in relatively recent radiations. The balance of
origination and extinction is fragile, and is likely to
become more so if increases in extinction due to habitat
destruction, climate change and other human activity are not
mitigated.},
Key = {fds229097}
}
@article{fds229104,
Author = {Mercer, JM},
Title = {Effective isotrophic dipole-dipole pair potential},
Journal = {Molecular Physics},
Volume = {69},
Pages = {625-638},
Year = {1990},
Key = {fds229104}
}
@article{fds229103,
Author = {Mercer, JM and Keyes, T},
Title = {Expansion of the kinetic hierarchy for a massive particle:
the Repeated Ring and Fokker-Planck equations},
Journal = {Journal of Statistical Physics},
Volume = {32},
Pages = {35-51},
Year = {1983},
Key = {fds229103}
}
@article{fds229101,
Author = {Keyes, and T, and Morita, T and Mercer, JM},
Title = {Further developments of the approach of Peralta and Zwanzig.
1. The drag on a sphere at high density},
Journal = {Journal of Chemical Physics},
Volume = {74},
Pages = {5281-5286},
Year = {1981},
Key = {fds229101}
}
@article{fds229106,
Author = {Liu, J and Mercer, JM and Stam, LF and Gibson, GC and Zeng, ZB and Laurie,
CC},
Title = {Genetic analysis of a morphological shape difference in the
male genitalia of Drosophila simulans and D.
mauritiana.},
Journal = {Genetics},
Volume = {142},
Number = {4},
Pages = {1129-1145},
Year = {1996},
Month = {April},
ISSN = {0016-6731},
url = {http://www.ncbi.nlm.nih.gov/pubmed/8846893},
Abstract = {Two closely related species of Drosophila, D. simulans and
D. mauritiana, differ markedly in morphology of the
posterior lobe of the male genital arch. Both size and shape
aspects of lobe variation can be quantified by a
morphometric descriptor based on elliptical Fourier and
principal components analyses. The genetic architecture of
this quantitative trait (PC1) was investigated by
hybridizing inbred lines to produce two backcross
populations approximately 200 individuals each, which were
analyzed jointly by a composite interval mapping procedure
with the aid of 18 marker loci. The parental lines show a
large difference in PC1 (30.4 environmental standard
deviations), and the markers account for > 80% of the
phenotypic variation in backcross populations. Eight of 15
intervals analyzed show convincing evidence of quantitative
trait loci (QTL), and the range of estimated QTL effects is
5.7-15.9% of the parental difference (1.7-4.8 environmental
standard deviations). These estimates may represent the
joint effects of multiple QTL within a single interval
(which averaged 23 cM in length). Although there is some
evidence of partial dominance of mauritiana alleles and for
epistasis, the pattern of inheritance is largely
additive.},
Doi = {10.1093/genetics/142.4.1129},
Key = {fds229106}
}
@article{fds229111,
Author = {Zeng, ZB and Liu, J and Stam, LF and Kao, CH and Mercer, JM and Laurie,
CC},
Title = {Genetic Architecture of a Morphological Shape Difference
Between Two Drosophila Species},
Journal = {Genetics},
Volume = {154},
Number = {1},
Pages = {299-310},
Year = {2000},
Month = {January},
ISSN = {0016-6731},
Abstract = {http://www.genetics.org/cgi/content/abstract/154/1/299},
Key = {fds229111}
}
@article{fds229099,
Author = {Stanley, and WL, and Walters, GG and Mercer, JM},
Title = {Lactase and other enzymes bound to chitin with
gluteraldehyde},
Journal = {Biotech. Bio.},
Volume = {17},
Pages = {315-326},
Year = {1975},
Key = {fds229099}
}
@article{fds300298,
Author = {Turck, CJ and Frazee, E and Kram, B and Daley, MJ and Day, SA and Horner,
D and Lesch, C and Mercer, JM and Plewa, AM and Herout, P and Critical Care
Pharmacotherapy Literature Update Group},
Title = {Major publications in the critical care pharmacotherapy
literature: February 2012 through February
2013.},
Journal = {American journal of health-system pharmacy : AJHP : official
journal of the American Society of Health-System
Pharmacists},
Volume = {71},
Number = {1},
Pages = {68-77},
Year = {2014},
Month = {January},
url = {http://www.ncbi.nlm.nih.gov/pubmed/24352184},
Abstract = {<h4>Purpose</h4>Recent impactful additions to the
professional literature on the role of pharmacotherapy in
treating the critically ill are summarized.<h4>Summary</h4>An
unusually large number of updated practice guidelines and
other publications with broad critical care pharmacotherapy
ramifications appeared in the primary biomedical literature
during the designated review period (February 2012-February
2013). Hundreds of relevant articles were evaluated by the
Critical Care Pharmacotherapy Literature Update group
(CCPLU), a national group of pharmacists who routinely
monitor 25 peer-reviewed journals for emerging evidence that
pertains to rational medication use in the intensive care
unit (ICU) setting. From among those articles, 64 were
summarized for dissemination to CCPLU members; the 8
publications deemed to have the greatest utility for
critical care practitioners, as determined by CCPLU through
a voting process, were selected for inclusion in this
review, with preference given to evidence meeting high
standards of methodological quality. The summaries presented
here include (1) important new recommendations on management
of pain, agitation, and delirium in critically ill patients,
(2) a comprehensive update of a practice guideline issued in
2008 by the Surviving Sepsis Campaign, (3) novel strategies
for the prevention and/or treatment of hyperglycemia in
critical care, and (4) reports on clinical trials of
promising alternative methods of sedation for use in weaning
patients from mechanical ventilation.<h4>Conclusion</h4>This
review provides synopses of practice guidelines and other
recent additions to the professional literature pertaining
to rational medication use in the ICU practice
setting.},
Doi = {10.2146/ajhp130303},
Key = {fds300298}
}
@misc{fds30310,
Author = {V. L. Roth and S. Unsicker and J. M. Mercer},
Title = {Mandibles of rodents that have cheek pouches differ
morphometrically from those of rodents that do
not},
Journal = {Poster: 7th International conference of Vertebrate
Morphology},
Year = {2004},
Month = {August},
Key = {fds30310}
}
@article{fds229112,
Author = {Louise Roth and V and Mercer, JM},
Title = {Morphometrics in development and evolution},
Journal = {American Zoologist},
Volume = {40},
Number = {5},
Pages = {801-810},
Publisher = {Society for Integrative and Comparative Biology},
Year = {2000},
Month = {January},
ISSN = {0003-1569},
url = {http://dx.doi.org/10.1093/icb/40.5.801},
Abstract = {SYNOPSIS. Morphometric approaches facilitate the analysis of
quantitative variation in form, typically becoming most
useful for the study of organisms that have completed
morphogenesis and arc at differing stages of growth. Recent
conceptual and technical refinements in the characterization
and comparison of forms have joined methodological
innovations in molecular biology, embryology, and phytogeny
reconstruction to advance the study of the evolution of
development. Among the phenomena that have recently been
examined morphometrically are developmental integration and
heterochrony, discoveries that in turn raise deeper
questions about the connections among disciplines and among
levels of description: the relationship between morphometric
variables and characters, between phenomenology and process,
and the interplay (and evolutionary relevance) of genes and
phenotypes. Morphometrics can continue to play a vital role
in evolutionary studies of-development as its results
generate questions both for its practitioners and for other
sorts of biologists to explore.},
Doi = {10.1093/icb/40.5.801},
Key = {fds229112}
}
@article{fds229108,
Author = {Siegel, SJ and Percopo, CM and Dyer, KD and Zhao, W and Roth, VL and Mercer, JM and Rosenberg, HF},
Title = {RNase 1 genes from the family Sciuridae define a novel
rodent ribonuclease cluster.},
Journal = {Mammalian genome : official journal of the International
Mammalian Genome Society},
Volume = {20},
Number = {11-12},
Pages = {749-757},
Year = {2009},
Month = {November},
ISSN = {0938-8990},
url = {http://dx.doi.org/10.1007/s00335-009-9215-4},
Abstract = {The RNase A ribonucleases are a complex group of
functionally diverse secretory proteins with conserved
enzymatic activity. We have identified novel RNase 1 genes
from four species of squirrel (order Rodentia, family
Sciuridae). Squirrel RNase 1 genes encode typical RNase A
ribonucleases, each with eight cysteines, a conserved
CKXXNTF signature motif, and a canonical
His(12)-Lys(41)-His(119) catalytic triad. Two alleles encode
Callosciurus prevostii RNase 1, which include a
Ser(18)<-->Pro, analogous to the sequence polymorphisms
found among the RNase 1 duplications in the genome of Rattus
exulans. Interestingly, although the squirrel RNase 1 genes
are closely related to one another (77-95% amino acid
sequence identity), the cluster as a whole is distinct and
divergent from the clusters including RNase 1 genes from
other rodent species. We examined the specific sites at
which Sciuridae RNase 1s diverge from Muridae/Cricetidae
RNase 1s and determined that the divergent sites are located
on the external surface, with complete sparing of the
catalytic crevice. The full significance of these findings
awaits a more complete understanding of biological role of
mammalian RNase 1s.},
Doi = {10.1007/s00335-009-9215-4},
Key = {fds229108}
}
@article{fds152963,
Author = {J.M. Mercer},
Title = {Roth, VL & JM Mercer 2008. Differing rates of
macroevolutionary diversification in arboreal squirrels.
Current Science 95:857-86},
Year = {2008},
Month = {October},
Abstract = {Current diversity is the result of macroevolutionary
processes of origination and extinction of lineages through
time. Here we make use of a fossil-calibrated
molecular-clock phylogeny of modern squirrel genera to
estimate both rates of 'birth' and 'death', and the net rate
of accumulation of lineages since the origin of the squirrel
family (Sciuridae) 36 Ma. As a family, the Sciuridae have
exhibited modest rates of diversification in comparison with
other mammalian clades. Within the Sciuridae, lineages of
squirrels have accumulated at higher rates in geographically
localized subclades in the tropics of different continents.
The rate is strikingly high in the Sciurini of South
America, which first entered and radiated within that
continent comparatively recently (less than 3 Ma). It is
noteworthy that the most rapidly diversifying groups are
also relatively young. Because extinctions lag behind
originations, the effects of extinction are not yet
detectable in relatively recent radiations. The balance of
origination and extinction is fragile, and is likely to
become more so if increases in extinction due to habitat
destruction, climate change, and other human activity are
not mitigated.},
Key = {fds152963}
}
@misc{fds300294,
Author = {Fernandez de la Mora and J and Mercer, JM and Rosner, DE and Fenn,
JB},
Title = {Simplified kinetic treatment of heavy molecule velocity
persistence effects: Application to species
separation},
Volume = {74},
Pages = {617-626},
Booktitle = {Rarefied Gas Dynamics: Progress in Astronautics and
Aeronautics},
Editor = {Fisher, SS},
Year = {1981},
Key = {fds300294}
}
@article{fds229109,
Author = {Bennett, SM and Mercer, JM and Noor, MAF},
Title = {Slip-sliding away: serial changes and homoplasy in repeat
number in the Drosophila yakuba homolog of human cancer
susceptibility gene BRCA2.},
Journal = {PloS one},
Volume = {5},
Number = {6},
Pages = {e11006},
Year = {2010},
Month = {June},
ISSN = {1932-6203},
url = {http://www.ncbi.nlm.nih.gov/pubmed/20543987},
Abstract = {Several recent studies have examined the function and
evolution of a Drosophila homolog to the human breast cancer
susceptibility gene BRCA2, named dmbrca2. We previously
identified what appeared to be a recent expansion in the
RAD51-binding BRC-repeat array in the ancestor of Drosophila
yakuba. In this study, we examine patterns of variation and
evolution of the dmbrca2 BRC-repeat array within D. yakuba
and its close relatives. We develop a model of how unequal
crossing over may have produced the expanded form, but we
also observe short repeat forms, typical of other species in
the D. melanogaster group, segregating within D. yakuba and
D. santomea. These short forms do not appear to be
identical-by-descent, suggesting that the history of dmbrca2
in the D. melanogaster subgroup has involved repeat unit
contractions resulting in homoplasious forms. We conclude
that the evolutionary history of dmbrca2 in D. yakuba and
perhaps in other Drosophila species may be more complicated
than can be inferred from examination of the published
single genome sequences per species.},
Doi = {10.1371/journal.pone.0011006},
Key = {fds229109}
}
@article{fds229100,
Author = {Keyes, T and Mercer, JM},
Title = {Some considerations on the calculation of the velocity
correlation function in the ring approximation, with
application to the Lorentz gas},
Journal = {Physica},
Volume = {95A},
Pages = {473-486},
Year = {1979},
Key = {fds229100}
}
@article{fds229113,
Author = {Mercer, JM and Roth, VL},
Title = {The effects of Cenozoic global change on squirrel
phylogeny.},
Journal = {Science (New York, N.Y.)},
Volume = {299},
Number = {5612},
Pages = {1568-1572},
Publisher = {American Association for the Advancement of
Science},
Year = {2003},
Month = {March},
url = {http://www.ncbi.nlm.nih.gov/pubmed/12595609},
Abstract = {By modifying habitats and creating bridges and barriers
between landmasses, climate change and tectonic events are
believed to have important consequences for diversification
of terrestrial organisms. Such consequences should be most
evident in phylogenetic histories of groups that are
ancient, widespread, and diverse. The squirrel family
(Sciuridae) is one of very few mammalian families endemic to
Eurasia, Africa, and North and South America and is ideal
for examining these issues. Through phylogenetic and
molecular-clock analyses, we infer that arrival and
diversification of squirrels in Africa, on Sunda Shelf
islands, across Beringea, and across the Panamanian isthmus
coincide in timing and location with multiple
well-documented sea-level, tectonic, and paleontological
events. These precise correspondences point to an important
role for global change in the diversification of a major
group of mammals.},
Doi = {10.1126/science.1079705},
Key = {fds229113}
}
@misc{fds300297,
Author = {Roth, VL and Mercer, JM},
Title = {Themes and variation in sciurid evolution},
Series = {Cambridge studies in morphology & molecules: new paradigms
in evolutionary biology},
Pages = {221-245},
Booktitle = {Evolution of the Rodents: Advances in Phylogenetics,
Functional Morphology and Development},
Publisher = {Cambridge University Press},
Editor = {Cox, PG and Hautier, L},
Year = {2015},
ISBN = {9781107044333},
url = {http://dx.doi.org/10.1017/CBO9781107360150.009},
Abstract = {With a species diversity approaching 300 (Thorington and
Hoffmann, 2005) and nearly worldwide in their distribution,
squirrels are common and important elements of many
ecological communities. The diurnal habits of most taxa
together with their relative conformity in body plan make
them familiar and easily recognized by both scientists and
non-specialists. The squirrel family, Sciuridae, also has a
long history of recognition by taxonomists as a coherent
grouping, despite its comprising distinctive forms
associated with use of different locomotor substrates (Table
8.1). At times, burrowing or gliding forms have been
separated from the archetypal arboreal squirrels: Fischer de
Waldheim (1817), the authority credited for naming the
Sciuridae (Thorington and Hoffmann, 2005), advocated use of
limb structure in recognizing groups of mammals, and
accordingly, he removed flying squirrels (‘Petauristus’,
Fischer de Waldheim, 1817: p. 422) to another ‘Division’
apart from ‘Familia Sciuriorum’ (p. 408), even though
Linnaeus had placed flying squirrels together with tree and
some ground squirrels under SCIURUS (Linnaeus, 1758: pp.
63-64; see Table 8.1). Woodchucks and marmots have also
posed something of a problem, to Linnaeus (1758:p. 60), who
listed them under ‘MUS’, and to many subsequent authors
who also set them apart from other sciurids. However, by
late 1839 (according to Brandt, 1855: p. 106, and Alston,
1876: p. 62) all of these animals had been combined by
Waterhouse to form a version of Sciuridae that would be
congruent with the modern concept of the family. Along the
way, dormice (referred to as ‘Myoxus’) have often crept
into lists of squirrels (e.g. Fischer de Waldheim, 1817, but
not those of Linnaeus before him or Brandt subsequently),
both their exclusion and their inclusion foreshadowing
current views based on molecular evidence that dormice are
distinct from sciurids but have closer affinities with them
(plus aplodontids) than with other rodent families (e.g.
Blanga-Kanfi et al., 2009; Churakov et al., 2010; Fabre et
al., 2012).},
Doi = {10.1017/CBO9781107360150.009},
Key = {fds300297}
}
@misc{fds300295,
Author = {Mercer, JM},
Title = {Unequal crossing-over},
Series = {2nd},
Pages = {252-256},
Booktitle = {Sydney Brenner's Encyclopedia of Genetics},
Publisher = {Elsevier},
Editor = {Maloy, S and Hughes, K},
Year = {2013},
ISBN = {9780123749840},
url = {http://dx.doi.org/10.1016/B978-0-12-374984-0.01604-1},
Abstract = {Unequal crossing-over (UCO) occurs when distinct loci
similar in sequence undergo homologous recombination. UCO
was inferred from a series of experiments on the Bar locus
in Drosophila melanogaster, demonstrating that crossing-over
occurred in conjunction with Bar locus mutations. The
process may result in duplication and deletion of genetic
material, formation of chimeric genes, and the generation of
mobile extrachromosomal elements. Contemporary studies of
newly abundant genomic data show multicellular genomes to be
filled with gene families whose formation can best be
understood through UCO. Primates have been found to have
substantial copy number variation (CNV) generated through
nonallelic homologous recombination (NAHR), a type of UCO
that occurs among highly similar sequences. The genetic
variation produced is substantial, exceeding even
single-nucleotide polymorphisms (SNPs) on a per-base-pair
basis. That variation has major genetic disease-generating
capability but also provides new variation for evolutionary
processes. UCO plays a central role in chromosomal
rearrangements (inversions, translocations), gene
duplication, and tandem duplication of functional and
structural modules especially in multicellular organisms,
generation of gene families, and generation of mobile
genetic materials such as exons - all important sources of
the genetic variation necessary for evolution.},
Doi = {10.1016/B978-0-12-374984-0.01604-1},
Key = {fds300295}
}