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| Neurosciences : Publications since January 2023List all publications in the database. :chronological alphabetical combined listing:%% LaBar, Kevin S. @article{fds375524, Author = {Neacsiu, AD and Beynel, L and Gerlus, N and LaBar, KS and Bukhari-Parlakturk, N and Rosenthal, MZ}, Title = {An experimental examination of neurostimulation and cognitive restructuring as potential components for Misophonia interventions.}, Journal = {J Affect Disord}, Volume = {350}, Pages = {274-285}, Year = {2024}, Month = {April}, url = {http://dx.doi.org/10.1016/j.jad.2024.01.120}, Abstract = {Misophonia is a disorder of decreased tolerance to certain aversive, repetitive common sounds, or to stimuli associated with these sounds. Two matched groups of adults (29 participants with misophonia and 30 clinical controls with high emotion dysregulation) received inhibitory neurostimulation (1 Hz) over a personalized medial prefrontal cortex (mPFC) target functionally connected to the left insula; excitatory neurostimulation (10 Hz) over a personalized dorsolateral PFC (dlPFC) target; and sham stimulation over either target. Stimulations were applied while participants were either listening or cognitively downregulating emotions associated with personalized aversive, misophonic, or neutral sounds. Subjective units of distress (SUDS) and psychophysiological measurements (e.g., skin conductance response [SCR] and level [SCL]) were collected. Compared to controls, participants with misophonia reported higher distress (∆SUDS = 1.91-1.93, ps < 0.001) when listening to and when downregulating misophonic distress. Both types of neurostimulation reduced distress significantly more than sham, with excitatory rTMS providing the most benefit (Cohen's dSUDS = 0.53; dSCL = 0.14). Excitatory rTMS also enhanced the regulation of emotions associated with misophonic sounds in both groups when measured by SUDS (dcontrol = 1.28; dMisophonia = 0.94), and in the misophonia group alone when measured with SCL (d = 0.20). Both types of neurostimulation were well tolerated. Engaging in cognitive restructuring enhanced with high-frequency neurostimulation led to the lowest misophonic distress, highlighting the best path forward for misophonia interventions.}, Doi = {10.1016/j.jad.2024.01.120}, Key = {fds375524} } @article{fds374231, Author = {Reeck, C and LaBar, KS}, Title = {Retrieval-induced forgetting of emotional memories.}, Journal = {Cognition & emotion}, Volume = {38}, Number = {1}, Pages = {131-147}, Year = {2024}, Month = {February}, url = {http://dx.doi.org/10.1080/02699931.2023.2279156}, Abstract = {Long-term memory manages its contents to facilitate adaptive behaviour, amplifying representations of information relevant to current goals and expediting forgetting of information that competes with relevant memory traces. Both mnemonic selection and inhibition maintain congruence between the contents of long-term memory and an organism's priorities. However, the capacity of these processes to modulate affective mnemonic representations remains ambiguous. Three empirical experiments investigated the consequences of mnemonic selection and inhibition on affectively charged and neutral mnemonic representations using an adapted retrieval practice paradigm. Participants encoded neutral cue words and affectively negative or neutral associates and then selectively retrieved a subset of these associates multiple times. The consequences of selection and inhibitory processes engaged during selective retrieval were evaluated on a final memory test in which recall for all studied associates was probed. Analyses of memory recall indicated that both affectively neutral and negative mnemonic representations experienced similar levels of enhancement and impairment following selective retrieval, demonstrating the susceptibility of affectively salient memories to these mnemonic processes. These findings indicate that although affective memories may be more strongly encoded in memory, they remain amenable to inhibition and flexibly adaptable to the evolving needs of the organism.}, Doi = {10.1080/02699931.2023.2279156}, Key = {fds374231} } @article{fds367262, Author = {Faul, L and LaBar, KS}, Title = {Mood-congruent memory revisited.}, Journal = {Psychological review}, Volume = {130}, Number = {6}, Pages = {1421-1456}, Year = {2023}, Month = {November}, url = {http://dx.doi.org/10.1037/rev0000394}, Abstract = {Affective experiences are commonly represented by either transient emotional reactions to discrete events or longer term, sustained mood states that are characterized by a more diffuse and global nature. While both have considerable influence in shaping memory, their interaction can produce mood-congruent memory (MCM), a psychological phenomenon where emotional memory is biased toward content affectively congruent with a past or current mood. The study of MCM has direct implications for understanding how memory biases form in daily life, as well as debilitating negative memory schemas that contribute to mood disorders such as depression. To elucidate the factors that influence the presence and strength of MCM, here we systematically review the literature for studies that assessed MCM by inducing mood in healthy participants. We observe that MCM is often reported as enhanced accuracy for previously encoded mood-congruent content or preferential recall for mood-congruent autobiographical events, but may also manifest as false memory for mood-congruent lures. We discuss the relevant conditions that shape these effects, as well as instances of mood-incongruent recall that facilitate mood repair. Further, we provide guiding methodological and theoretical considerations, emphasizing the limited neuroimaging research in this area and the need for a renewed focus on memory consolidation. Accordingly, we propose a theoretical framework for studying the neural basis of MCM based on the neurobiological underpinnings of mood and emotion. In doing so, we review evidence for associative network models of spreading activation, while also considering alternative models informed by the cognitive neuroscience literature of emotional memory bias. (PsycInfo Database Record (c) 2024 APA, all rights reserved).}, Doi = {10.1037/rev0000394}, Key = {fds367262} } @article{fds367771, Author = {Faul, L and Baumann, MG and LaBar, KS}, Title = {The representation of emotional experience from imagined scenarios.}, Journal = {Emotion (Washington, D.C.)}, Volume = {23}, Number = {6}, Pages = {1670-1686}, Year = {2023}, Month = {September}, url = {http://dx.doi.org/10.1037/emo0001192}, Abstract = {One of the key unresolved issues in affective science is understanding how the subjective experience of emotion is structured. Semantic space theory has shed new light on this debate by applying computational methods to high-dimensional data sets containing self-report ratings of emotional responses to visual and auditory stimuli. We extend this approach here to the emotional experience induced by imagined scenarios. Participants chose at least one emotion category label among 34 options or provided ratings on 14 affective dimensions while imagining two-sentence hypothetical scenarios. A total of 883 scenarios were rated by at least 11 different raters on categorical or dimensional qualities, with a total of 796 participants contributing to the final normed stimulus set. Principal component analysis reduced the categorical data to 24 distinct varieties of reported experience, while cluster visualization indicated a blended, rather than discrete, distribution of the corresponding emotion space. Canonical correlation analysis between the categorical and dimensional data further indicated that category endorsement accounted for more variance in dimensional ratings than vice versa, with 10 canonical variates unifying change in category loadings with affective dimensions such as valence, arousal, safety, and commitment. These findings indicate that self-reported emotional responses to imaginative experiences exhibit a clustered structure, although clusters are separated by fuzzy boundaries, and variable dimensional properties associate with smooth gradients of change in categorical judgments. The resultant structure supports the tenets of semantic space theory and demonstrates some consistency with prior work using different emotional stimuli. (PsycInfo Database Record (c) 2023 APA, all rights reserved).}, Doi = {10.1037/emo0001192}, Key = {fds367771} } @article{fds370956, Author = {Faul, L and Rothrock, JM and LaBar, KS}, Title = {Self-Relevance Moderates the Relationship between Depressive Symptoms and Corrugator Activity during the Imagination of Personal Episodic Events.}, Journal = {Brain sciences}, Volume = {13}, Number = {6}, Pages = {843}, Publisher = {MDPI AG}, Year = {2023}, Month = {May}, url = {http://dx.doi.org/10.3390/brainsci13060843}, Abstract = {Accumulating evidence suggests depression is associated with blunted reactivity to positive and negative stimuli, known as emotion context insensitivity (ECI). However, ECI is not consistently observed in the literature, suggesting moderators that influence its presence. We propose self-relevance as one such moderator, with ECI most apparent when self-relevance is low. We examined this proposal by measuring self-report and facial electromyography (EMG) from the corrugator muscle while participants (n = 81) imagined hypothetical scenarios with varying self-relevance and recalled autobiographical memories. Increased depressive symptoms on the Center for Epidemiologic Studies Depression Scale were associated with less differentiated arousal and self-relevance ratings between happy, neutral, and sad scenarios. EMG analyses further revealed that individuals with high depressive symptoms exhibited blunted corrugator reactivity (reduced differentiation) for sad, neutral, and happy scenarios with low self-relevance, while corrugator reactivity remained sensitive to valence for highly self-relevant scenarios. By comparison, in individuals with low depressive symptoms, corrugator activity differentiated valence regardless of stimulus self-relevance. Supporting a role for self-relevance in shaping ECI, we observed no depression-related differences in emotional reactivity when participants recalled highly self-relevant happy or sad autobiographical memories. Our findings suggest ECI is primarily associated with blunted reactivity towards material deemed low in self-relevance.}, Doi = {10.3390/brainsci13060843}, Key = {fds370956} } @article{fds371648, Author = {LaBar, KS}, Title = {Neuroimaging of Fear Extinction.}, Journal = {Current topics in behavioral neurosciences}, Volume = {64}, Pages = {79-101}, Year = {2023}, Month = {January}, url = {http://dx.doi.org/10.1007/7854_2023_429}, Abstract = {Extinguishing fear and defensive responses to environmental threats when they are no longer warranted is a critical learning ability that can promote healthy self-regulation and, ultimately, reduce susceptibility to or maintenance of affective-, trauma-, stressor-,and anxiety-related disorders. Neuroimaging tools provide an important means to uncover the neural mechanisms of effective extinction learning that, in turn, can abate the return of fear. Here I review the promises and pitfalls of functional neuroimaging as a method to investigate fear extinction circuitry in the healthy human brain. I discuss the extent to which neuroimaging has validated the core circuits implicated in rodent models and has expanded the scope of the brain regions implicated in extinction processes. Finally, I present new advances made possible by multivariate data analysis tools that yield more refined insights into the brain-behavior relationships involved.}, Doi = {10.1007/7854_2023_429}, Key = {fds371648} } @article{fds373632, Author = {Faul, L and Baumann, MG and LaBar, KS}, Title = {The Representation of Emotional Experience from Imagined Scenarios}, Journal = {AFFECTIVE SCIENCE}, Volume = {4}, Number = {1}, Year = {2023}, Key = {fds373632} } | |
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