Publications [#52401] of Amy Bejsovec
search PubMed.Papers Published
- A. Bejsovec, Flying at the head of the pack: Wnt biology in Drosophila,
Oncogene, vol. 25
(2006),
pp. 7442-7449 .
(last updated on 2006/12/29)Abstract:
The fruitfly, Drosophila melanogaster, has been of central importance in analyzing the mechanics of cellular processes. Classic forward genetic screens in the fly have identified many of the genes that define critical cell signaling pathways, for example. Our understanding of the Wnt pathway in particular has benefitted from the many advantages that the fly offers as a model system. Here, I review the history of these discoveries and highlight the utility of the fly in dissecting the molecular workings of Wnt signal transduction.