Publications [#233220] of Andrew T. McPhail

Journal Articles

  1. Sakensa, AK; Jao, E; Murphy, B; Schumacher, D; Chan, TM; Puar, MS; Jenkins, JK; Maloney, D; Cordero, M; Pramanik, BN; Bartner, P; Dias, PR; McPhail, AT; Girijavallabhan, VM; Ganguly, AK, "Structure Elucidation of Sch 49088, a Novel Everninomicin Antibiotic Containing an Unusual Hydroxylamino-Ether Sugar, Everhydroxylaminose", Tetrahedron Letters, 1998, 39(46), 8441-8444, Elsevier BV [Gateway.cgi], [doi].
    (last updated on 2026/01/21)

    Abstract:
    Degradation of Sch 49088 (1) provided a novel, highly functionalized O- substituted hydroxylamine-containing sugar, everhydroxylaminose 11 isolated as a β-OMe glycoside. Notably the two acid sensitive orthoester moieties in the intact antibiotic 1 co-exist in the presence of three phenolic groups and a free carboxylic acid group.